Kazuhiko Igarashi
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Computer Science
Kazuhiko Igarashi's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Kazuhiko Igarashi's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. (1997) (3591)
- Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. (1999) (3144)
- Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2 (2004) (1881)
- A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase. (1993) (761)
- Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site (1996) (612)
- Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene (2002) (575)
- Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1 (2001) (490)
- Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins (1994) (419)
- Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins (1995) (402)
- DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics (2007) (380)
- Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRP (1991) (338)
- Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network. (2004) (335)
- Bach2 represses effector programmes to stabilize Treg-mediated immune homeostasis (2013) (325)
- Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages (2014) (318)
- The world according to Maf. (1997) (278)
- Molecular Cloning and Functional Characterization of a New Cap’n’ Collar Family Transcription Factor Nrf3* (1999) (277)
- Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds. (2009) (269)
- The transcriptional programme of antibody class switching involves the repressor Bach2 (2004) (268)
- Bach1 Functions as a Hypoxia-inducible Repressor for the Heme Oxygenase-1 Gene in Human Cells* (2003) (260)
- The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells (2005) (257)
- The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. (2006) (237)
- Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics (2004) (221)
- Heme Induces Ubiquitination and Degradation of the Transcription Factor Bach1 (2007) (220)
- Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (1995) (213)
- Heme regulates gene expression by triggering Crm1‐dependent nuclear export of Bach1 (2004) (204)
- S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1. (2017) (199)
- Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer (1998) (195)
- BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers (2016) (181)
- Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch (2010) (173)
- Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. (2011) (162)
- Cadmium Induces Nuclear Export of Bach1, a Transcriptional Repressor of Heme Oxygenase-1 Gene* (2003) (150)
- Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells* (2006) (148)
- Activation of β-major globin gene transcription is associated with recruitment of NF-E2 to the β-globin LCR and gene promoter (2001) (142)
- Mitochondrial function provides instructive signals for activation-induced B-cell fates (2015) (127)
- Functional map of the alpha subunit of Escherichia coli RNA polymerase: two modes of transcription activation by positive factors. (1991) (119)
- A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain (2000) (119)
- Ribosome modulation factor: stationary growth phase-specific inhibitor of ribosome functions from Escherichia coli. (1995) (119)
- Mapping the cAMP receptor protein contact site on the α subunit of Escherichia coli RNA polymerase (1992) (115)
- Bach2 maintains T cells in a naive state by suppressing effector memory-related genes (2013) (112)
- Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the International Conference (Uppsala, 2003) on Heme Oxygenase. (2004) (109)
- Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6. (2008) (108)
- Suppression of Rat Thromboxane Synthase Gene Transcription by Peroxisome Proliferator-activated Receptor γ in Macrophages via an Interaction with NRF2* (2000) (105)
- Oxidative Stress Abolishes Leptomycin B-sensitive Nuclear Export of Transcription Repressor Bach2 That Counteracts Activation of Maf Recognition Element* (2000) (105)
- Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif (1997) (104)
- Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells. (2004) (103)
- BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint (2013) (102)
- Bach1 Repression of Ferritin and Thioredoxin Reductase1 Is Heme-sensitive in Cells and in Vitro and Coordinates Expression with Heme Oxygenase1, β-Globin, and NADP(H) Quinone (Oxido) Reductase1* (2007) (102)
- Heme Positively Regulates the Expression of β-Globin at the Locus Control Region via the Transcriptional Factor Bach1 in Erythroid Cells* (2004) (102)
- Construction and properties of a recombinant herpes simplex virus 1 lacking both S-component origins of DNA synthesis (1993) (99)
- The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program (2014) (98)
- Long range interaction of cis‐DNA elements mediated by architectural transcription factor Bach1 (1999) (96)
- Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function (2013) (96)
- Activity and Expression of Murine Small Maf Family Protein MafK (*) (1995) (95)
- Activation of Maf/AP-1 Repressor Bach2 by Oxidative Stress Promotes Apoptosis and Its Interaction with Promyelocytic Leukemia Nuclear Bodies* (2002) (93)
- Bach1, a heme‐dependent transcription factor, reveals presence of multiple heme binding sites with distinct coordination structure (2007) (90)
- E. coli RNA polymerase, deleted in the C-terminal part of its alpha-subunit, interacts differently with the cAMP-CRP complex at the lacP1 and at the galP1 promoter. (1993) (89)
- Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice (2006) (87)
- The Tohoku Medical Megabank Project: Design and Mission. (2016) (87)
- Wearing red for signaling: the heme-bach axis in heme metabolism, oxidative stress response and iron immunology. (2014) (85)
- Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin (2008) (85)
- Regulation of NF-E2 Activity in Erythroleukemia Cell Differentiation* (1998) (82)
- A deoxythymidine kinase deficient mutant of Escherichia coli. II. Mapping and transduction studies with phage phi 80. (1967) (81)
- BACH transcription factors in innate and adaptive immunity (2017) (81)
- Identification of a subunit assembly domain in the alpha subunit of Escherichia coli RNA polymerase. (1991) (78)
- Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1 (2019) (77)
- Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2. (2011) (76)
- Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective (2019) (73)
- Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2 (2017) (71)
- Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15 (2000) (70)
- Stimulation of the phage λ pL promoter by integration host factor requires the carboxy terminus of the α-subunit of RNA polymerase (1992) (68)
- Myocardial Protection Against Pressure Overload in Mice Lacking Bach1, a Transcriptional Repressor of Heme Oxygenase-1 (2008) (68)
- Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2. (1998) (66)
- A deoxythymidine kinase-deficient mutant of Escherichia coli. I. Isolation and some properties. (1967) (65)
- Functional specialization within the α-subunit of Escherichia coli RNA polymerase (1991) (64)
- Conditional expression of the ubiquitous transcription factor MafK induces erythroleukemia cell differentiation. (1995) (62)
- Promoter selectivity of Escherichia coli RNA polymerase: omega factor is responsible for the ppGpp sensitivity. (1989) (62)
- Reconstitution of Human β-Globin Locus Control Region Hypersensitive Sites in the Absence of Chromatin Assembly (2001) (61)
- Sequence analysis of two temperature-sensitive mutations in the alpha subunit gene (rpoA) of Escherichia coli RNA polymerase. (1990) (59)
- BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-1 (2013) (59)
- Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network (2014) (59)
- Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1 (2015) (58)
- Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage (2013) (57)
- Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1. (2007) (57)
- Repression of PML Nuclear Body-Associated Transcription by Oxidative Stress-Activated Bach2 (2004) (57)
- Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury (2005) (56)
- B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs. (2003) (55)
- Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells. (2004) (55)
- Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment. (2005) (55)
- Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study (2020) (54)
- Architecture and dynamics of the transcription factor network that regulates B-to-plasma cell differentiation. (2007) (54)
- The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression (2015) (54)
- Methionine Adenosyltransferase II-dependent Histone H3K9 Methylation at the COX-2 Gene Locus* (2013) (53)
- Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation (2016) (53)
- Ablation of the Bach1 Gene Leads to the Suppression of Atherosclerosis in Bach1 and Apolipoprotein E Double Knockout Mice (2008) (51)
- Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics (2013) (51)
- Small Maf Compound Mutants Display Central Nervous System Neuronal Degeneration, Aberrant Transcription, and Bach Protein Mislocalization Coincident with Myoclonus and Abnormal Startle Response (2003) (51)
- Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3* (2016) (51)
- Transcription Factor BACH1 Is Recruited to the Nucleus by Its Novel Alternative Spliced Isoform* (2001) (51)
- Targeted gene delivery to human osteosarcoma cells with magnetic cationic liposomes under a magnetic field. (2003) (49)
- Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene* (2013) (49)
- Activation defects caused by mutations in Escherichia coli rpoA are promoter specific (1992) (46)
- BACH1 promotes pancreatic cancer metastasis by repressing epithelial genes and enhancing epithelial-mesenchymal transition. (2020) (44)
- Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells (2017) (44)
- Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: a study of the Osaka Lymphoma Study Group. (2005) (43)
- Genetic ablation of transcription repressor Bach1 reduces neural tissue damage and improves locomotor function after spinal cord injury in mice. (2009) (42)
- [Transcriptional regulation of cellular senescence]. (2009) (42)
- Sck interacts with KDR and Flt-1 via its SH2 domain. (1998) (41)
- The mouse L-histidine decarboxylase gene: structure and transcriptional regulation by CpG methylation in the promoter region. (2000) (41)
- Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP. (2005) (39)
- A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors. (2017) (38)
- beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth. (2006) (38)
- Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model (2010) (37)
- O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1 (2018) (37)
- Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair (2016) (37)
- Involvement of polyamines in B cell receptor-mediated apoptosis: spermine functions as a negative modulator. (2001) (37)
- Mesodermal‐ vs. neuronal‐specific expression of MafK is elicited by different promoters (1996) (37)
- RNA polymerase mutants of Escherichia coli. I. Mutants resistant to streptovaricin. (1968) (36)
- Interaction and Cooperation of mi Transcription Factor (MITF) and Myc-associated Zinc-finger Protein-related Factor (MAZR) for Transcription of Mouse Mast Cell Protease 6 Gene* (2002) (36)
- Bach1 deficiency protects pancreatic β-cells from oxidative stress injury. (2013) (36)
- Proline cis/trans-Isomerase Pin1 Regulates Peroxisome Proliferator-activated Receptor γ Activity through the Direct Binding to the Activation Function-1 Domain* (2009) (35)
- Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors. (2018) (35)
- Polycomb Group Gene mel-18 Regulates Early T Progenitor Expansion by Maintaining the Expression of Hes-1, a Target of the Notch Pathway1 (2005) (34)
- Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6. (2009) (33)
- Down‐regulation of heme oxygenase‐2 is associated with the increased expression of heme oxygenase‐1 in human cell lines (2006) (33)
- Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence (2019) (32)
- TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages. (2019) (32)
- The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis. (1995) (32)
- Expression of the oxidative stress-regulated transcription factor bach2 in differentiating neuronal cells. (2002) (32)
- The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization* (2015) (30)
- Collagenase H is Crucial for Isolation of Rat Pancreatic Islets (2014) (29)
- Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency (2011) (29)
- Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons (2018) (28)
- Genetic heterogeneity in 26 infants with a hypomyelinating leukodystrophy (2015) (28)
- Heme binds to an intrinsically disordered region of Bach2 and alters its conformation. (2015) (28)
- The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif. (2014) (28)
- Metabolic aspects of epigenome: coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module. (2013) (28)
- Inhibition of Bach1 ameliorates indomethacin-induced intestinal injury in mice. (2009) (27)
- Target of rapamycin‐signaling modulates starch accumulation via glycogenin phosphorylation status in the unicellular red alga Cyanidioschyzon merolae (2018) (27)
- The Ada protein is a class I transcription factor of Escherichia coli (1993) (27)
- Transcriptional suppression of BACH2 by the Bcr-Abl oncoprotein is mediated by PAX5 (2013) (26)
- To be red or white: lineage commitment and maintenance of the hematopoietic system by the “inner myeloid” (2019) (25)
- Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells (2021) (25)
- Bach1-dependent and -independent Regulation of Heme Oxygenase-1 in Keratinocytes* (2010) (25)
- Zinc finger-IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell. (2018) (25)
- Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes (2017) (24)
- Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways. (2012) (24)
- Fission yeast homologues of the B′ subunit of protein phosphatase 2A: multiple roles in mitotic cell division and functional interaction with calcineurin (2001) (23)
- Infection perturbs Bach2- and Bach1-dependent erythroid lineage ‘choice’ to cause anemia (2018) (23)
- Bach1 deficiency ameliorates hepatic injury in a mouse model. (2009) (23)
- MiR-196a regulates heme oxygenase-1 by silencing Bach1 in the neonatal mouse lung. (2016) (23)
- Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1. (2020) (23)
- Microproteomics with microfluidic‐based cell sorting: Application to 1000 and 100 immune cells (2017) (22)
- The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation (2017) (22)
- Functional specialization within the alpha-subunit of Escherichia coli RNA polymerase. (1991) (22)
- Bach1 Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice (2014) (22)
- Heme oxygenase-1 gene enhancer manifests silencing activity in a chromatin environment prior to oxidative stress. (2006) (22)
- Bach1 Modulates Heme Oxygenase-1 Expression in the Neonatal Mouse Lung (2009) (21)
- The transcription factor BACH1 at the crossroads of cancer biology: From epithelial–mesenchymal transition to ferroptosis (2021) (21)
- Identification of senescence-associated genes and their networks under oxidative stress by the analysis of Bach1. (2011) (21)
- Bach2 Promotes B Cell Receptor–Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors (2018) (21)
- Regulation of heme oxygenase-1 by transcription factor Bach1 in the mouse brain (2008) (20)
- Abundant expression of erythroid transcription factor P45 NF-E2 mRNA in human peripheral granurocytes. (1996) (19)
- Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency (2016) (19)
- Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1‐Pparg pathway in adipogenesis (2016) (19)
- Oxidative stress reaction in the meniscus of Bach 1 deficient mice: Potential prevention of meniscal degeneration (2008) (19)
- Association between BACH2 expression and clinical prognosis in diffuse large B-cell lymphoma (2014) (18)
- N 1-methyladenosine (m1A) RNA modification: the key to ribosome control? (2020) (18)
- Solution structure of clostridial collagenase H and its calcium-dependent global conformation change. (2013) (18)
- The promoter of mouse transcription repressor bach1 is regulated by Sp1 and trans-activated by Bach1. (2001) (18)
- Bach1 is critical for the transformation of mouse embryonic fibroblasts by RasV12 and maintains ERK signaling (2013) (18)
- Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes (2017) (18)
- Cloning of a coproporphyrinogen oxidase promoter regulatory element binding protein. (2000) (18)
- Genetic complementation analysis showed distinct contributions of the N‐terminal tail of H2A.Z to epigenetic regulations (2016) (17)
- Orchestration of B lymphoid cells and their inner myeloid by Bach. (2016) (17)
- Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR. (2018) (17)
- Crystal structure of the Bach1 BTB domain and its regulation of homodimerization (2009) (17)
- The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis. (2016) (17)
- Synergistic Effect of Neutral Protease and Clostripain on Rat Pancreatic Islet Isolation (2015) (17)
- SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites (2017) (16)
- Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation. (2014) (16)
- Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression. (2007) (15)
- Ferroptosis: regulation by competition between NRF2 and BACH1 and propagation of the death signal (2022) (15)
- Stimulation of the phage lambda pL promoter by integration host factor requires the carboxy terminus of the alpha-subunit of RNA polymerase. (1992) (14)
- Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease (2021) (14)
- Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics (2017) (14)
- Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation (2016) (13)
- Discovery and structure--activity relationship studies of a novel and specific peptide motif, Pro-X-X-X-Asp-X, as a platelet fibrinogen receptor antagonist. (1998) (13)
- Atomic force microscopy proposes a ‘kiss and pull’ mechanism for enhancer function (2000) (13)
- FABP7 Regulates Acetyl-CoA Metabolism Through the Interaction with ACLY in the Nucleus of Astrocytes (2020) (12)
- Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population (2014) (12)
- Transcription‐independent role of Bach1 in mitosis through a nuclear exporter Crm1‐dependent mechanism (2012) (12)
- Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes. (2006) (12)
- Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes (2016) (12)
- Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis (2017) (12)
- Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region. (2016) (11)
- A novel liver metastasis-correlated protein of pancreatic neuroendocrine neoplasm (PanNEN) discovered by proteomic analysis (2018) (11)
- Stromal expression of hemopexin is associated with lymph-node metastasis in pancreatic ductal adenocarcinoma (2020) (11)
- Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A (2019) (11)
- Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4. (2020) (10)
- Nuclear positioning of the BACH2 gene in BCR‐ABL positive leukemic cells (2007) (10)
- Bach1‐mediated suppression of p53 is inhibited by p19ARF independently of MDM2 (2012) (9)
- Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells (2017) (9)
- Bach1 Plays an Important Role in Angiogenesis Through Regulation of Oxidative Stress. (2020) (9)
- MafB as a type I interferon rheostat (2010) (9)
- Heme-Regulated Transcription Factor Bach1 (2002) (8)
- Erratum: Small Maf proteins heterodimerize with fos and may act as competitive repressors of the NF-E2 transcription factor (Molecular and Cellular Biology (1995) 15:5 (2188)) (1995) (8)
- Epitope mapping and functional characterization of monoclonal antibodies specific for the alpha subunit of Escherichia coli RNA polymerase. (1994) (8)
- The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes. (2015) (8)
- The role of RNA polymerase in genetic transcription. (1969) (8)
- Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation (2020) (8)
- Haploinsufficient tumor suppressor Tip60 negatively regulates oncogenic Aurora B kinase (2019) (7)
- High Fractional Occupancy of a Tandem Maf Recognition Element and Its Role in Long-Range β-Globin Gene Regulation (2015) (7)
- Bach1 as a regulator of mitosis, beyond its transcriptional function (2012) (7)
- Strategy towards tailored donor tissue-specific pancreatic islet isolation (2019) (5)
- Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression (2018) (5)
- Endogenous Purification of NR4A2 (Nurr1) Identified Poly(ADP-Ribose) Polymerase 1 as a Prime Coregulator in Human Adrenocortical H295R Cells (2018) (5)
- Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1 (2021) (4)
- [Regulation of cellular senescence by Bach1]. (2009) (4)
- Biophysical characterization of heme binding to the intrinsically disordered region of Bach1 (2019) (4)
- Bach2 Controls Homeostasis of Eosinophils by Restricting the Type-2 Helper Function of T Cells. (2017) (4)
- Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2 (2017) (4)
- Actin Family Proteins in the Human INO80 Chromatin Remodeling Complex Exhibit Functional Roles in the Induction of Heme Oxygenase-1 with Hemin (2017) (4)
- Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s Disease (2022) (4)
- Functional Heme Binding to the Intrinsically Disordered C-Terminal Region of Bach1, a Transcriptional Repressor. (2019) (4)
- Potent inactivator of alpha-chymotrypsin: 2,2-dimethyl-3-(N-4-cyanobenzoyl)amino-5-phenyl pentanoic anhydride. (1997) (3)
- [Function of NF-E2-related transcription factors]. (2000) (3)
- The Cys‐Pro motifs in the intrinsically disordered regions of the transcription factor BACH1 mediate distinct and overlapping functions upon heme binding (2022) (3)
- Frequent downregulation of BTB and CNC homology 2 expression in Epstein–Barr virus‐positive diffuse large B‐cell lymphoma (2017) (3)
- Transgenic Expression of Bach1 Transcription Factor Results in Down-Regulation of the p45 Target Genes in Megakaryocytic Lineage Cells. (2004) (3)
- BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. (2022) (3)
- [Regulation of synthesis of proteins and nucleic acids by polyamines]. (1988) (3)
- The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification. (2008) (3)
- [Oxidative stress protection by heme]. (2002) (2)
- Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics (2013) (2)
- Over‐expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B‐cell lymphoma (2013) (2)
- Aurora kinase A-mediated phosphorylation of mPOU at a specific site drives skeletal muscle differentiation. (2020) (2)
- Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation (2019) (2)
- [Molecular mechanisms of oxidative stress response and implications in diseases]. (2006) (2)
- , the BTB / POZ Domain and MAZR ( MAZ-Related Factor ) through Generated by Transcription Factor Bach 2 A Combinatorial Code for Gene Expression (1999) (2)
- Autocitrullination and Changes in the Activity of Peptidylarginine Deiminase 3 Induced by High Ca2+ Concentrations (2022) (1)
- Ferroptosis is programmed by the coordinated regulation of glutathione and iron metabolism by BACH1 (2019) (1)
- Corrigendum to “Transcription‐independent role of Bach1 in mitosis through a nuclear exporter Crm1‐dependent mechanism” [FEBS Letters 586 (2012) 448–454] (2012) (1)
- Atomic force microscopy proposes a 'kiss and pull' mechanism for enhancer function. off. (2000) (1)
- [BTB/POZ domain proteins in nuclear structure and DNA loop formation]. (1999) (1)
- FRS-163 Genetic ablation of Bach1, a critical transcriptional repressor of heme oxygenase-1, leads to myocardial protection against ischemia/reperfusion injury in mice(Coronary Heart Disease : Basic Science (IHD) : FRS20)(Featured Research Session (English)) (2004) (1)
- mTORC1-independent translation control in mammalian cells by methionine adenosyltransferase 2A and S-adenosylmethionine (2022) (1)
- Protocol for in vitro BCR-mediated plasma cell differentiation and purification of chromatin-associated proteins (2021) (1)
- Comparative proteomic analysis to identify the novel target gene of angiotensin II in adrenocortical H295R cells. (2020) (1)
- Genetic BACH1 deficiency alters mitochondrial function and increases NLRP3 inflammasome activation in mouse macrophages (2022) (1)
- Identification of histone H3K36 methyltransferase Whsc1 protein complex (2016) (1)
- Transcription Factor Bach1 and Bach2 Operate Erythro-Myeloid Competitive Differentiation By Responding to Environmental Changes (2016) (1)
- A novel indication of the activities of small molecule inhibitors of protein-protein interactions: application of the yeast two-hybrid system. (1998) (1)
- Distinctive nuclear zone for RAD51-mediated homologous recombinational DNA repair (2021) (1)
- [RNA polymerase mutants of bacteria]. (1972) (1)
- Erratum for Shen et al., “Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression” (2019) (1)
- [Function of LCR-binding protein Bach1 as an architectural transcription factor]. (1998) (1)
- Mechanism Governing Heme Synthesis Reveals a GATA Factor-Heme Circuit That Controls Differentiation (2015) (1)
- Transcription Factor Bach1 and Bach2 Control Common Myeloid Progenitor Cell Differentiation Under Infectious Stimuli (2015) (1)
- Heme regulates gene expression by triggering Crm1‐dependent nuclear export of Bach1 (2014) (1)
- [Regulation of transcription by locus control regions]. (2000) (1)
- Functional screening of coregulators for a glucose-responsive transcriptional factor ChREBP. (2015) (0)
- Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis (2022) (0)
- 330 Deficiency of Bach2 results in improved tumor immunity by enhancing effector function in CD8 T cells (2017) (0)
- E.coli RNApolymerase, deleted intheC-terminal part of its a-subunit, interacts differently withthecAMP-CRP complex atthelacPl andatthega/Pl promoter (1993) (0)
- of anticancer drugs specific transcription factor BACH2 modifies the cytotoxic effects - B-cell (2013) (0)
- Autophagy driven by heme during erythropoiesis (2016) (0)
- NUCLEO-CYTOPLASMIC TRANSLOCATION OF BACH1 REGULATES THE EXPRESSION OF HEME OXYGENASE-1, AN ANTI-OXIDANT DEFENSE ENZYME. (2004) (0)
- Linking heme biosynthesis with a GATA factor-regulated genetic network that controls cellular differentiation (2015) (0)
- CmNDB1 and a Specific Domain of CmMYB1 Negatively Regulate CmMYB1-Dependent Transcription of Nitrate Assimilation Genes Under Nitrogen-Repleted Condition in a Unicellular Red Alga (2022) (0)
- Heme-dependent induction of mitophagy program during murine erythroid cell differentiation (2022) (0)
- Bach1 bi-polarizes cell fates into anti-aging alive and death through senescence regulation and ferroptosis (2017) (0)
- Analysis of the metabolic property of mouse primordial germ cells through multi-omics strategy (2016) (0)
- [Identification of proteins which are preferentially synthesized in the presence of polyamines]. (1989) (0)
- 3P108 Spectoroscopic analyses of heme-acceptor region of Bach2 protein(Heme proteins,The 48th Annual Meeting of the Biophysical Society of Japan) (2010) (0)
- 2P093 Heme binding region of Bach2 as intrinsically disordered protein(02. Heme proteins,Poster) (2013) (0)
- Deficiency of BACH1 Ameliorates TNBS-Induced Colitis in Mice Thorough the Anti-Inflammatory Function of HO-1 Highly Expressed Macrophages (2011) (0)
- [Transcription on chromatin: overview]. (2006) (0)
- Chemical and biological properties of the carcinostatic protein fraction of Escherichia coli. (1978) (0)
- Bach 1 deficiency protects pancreatic β-cells from oxidative stress 1 injury 2 3 Running title : Protective effects of Bach 1 deficiency in pancreatic 4 β-cells (2013) (0)
- Relationship between HO-1 Upregulation Capacity in PBMC and Severity of Coronary Hear Disease(Angina Pectoris, Basic/Clinical 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- Correction: Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (8289-8294) DOI: 10.1073/pnas.1620915114) (2018) (0)
- Epitranscriptome regulation by RNA modifications (2016) (0)
- Sa1945 Role of BTB and CNC Homolog 1 (BACH1) in Ischemia-Reperfusion-Challenged Intestinal Inflammation in Mice (2012) (0)
- GENETIC ABLATION OF BACH1, ATRANSCRIPTIONAL REPRESSOR OF HEME OXYGENASE-1, LEADS TO MYOCARDIAL PROTECTION AGAINST ISCHEMIA/REPERFUSION INJURY IN MICE: P 284 (2004) (0)
- Bach1 deficient mice reduce severity of age-related osteoarthritis (2013) (0)
- BACH2 Mediates Early B Cell Differentiation and Oncogene-Induced Senescence in Acute Lymphoblastic Leukemia (2011) (0)
- No . 2 319-326 E . coli RNA polymerase , deleted in the C-terminal part of its a-subunit , interacts differently with the cAMP-CRP complex at the lacPl and at the ga / Pl promoter (0)
- Biophysical characterization of heme binding to the intrinsically disordered region of Bach1 (2019) (0)
- Problems and solutions in developing wearable artificial kidney. (1986) (0)
- Methyl-Metabolite Depletion Elicits Coordinated Responses to Support Heterochromatin Stability and Epigenetic Persistence (2018) (0)
- The Mediator Subunit MED 16 Transduces NRF 2-activating Signals into 1 Antioxidant Gene Expression 2 3 (2015) (0)
- Analyses of Heme-Regulated Genes during Erythoid Differentiation. (2007) (0)
- Transcription factor Bach1 as an oxidative stress-dependent tumor suppressor (2017) (0)
- [PotD protein: three-dimensional structure and function]. (1997) (0)
- Correction to: Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency (2013) (0)
- Iron in Cancer Progression: Does BACH1 Promote Metastasis by Altering Iron Homeostasis? (2022) (0)
- 032 Bach2 suppresses tumor immunity by repressing effector function-related gene in CD8+ T cells (2017) (0)
- Abstract B7: Cross‐talk between Bach1, NF‐кB and IL‐6 in epithelial‐mesenchymal transition (2009) (0)
- 958 BACH1 Deficiency Leads to the Suppression of Indomethacin-Induced Apoptosis in the Small Intestine (2010) (0)
- [Extensive analysis of protein phosphorylation: An example of transcription factor Bach2]. (2016) (0)
- Effects of S-adenosylmethionine metabolism upon methylation of RNA and histone (2016) (0)
- Construction andProperties ofa Recombinant HerpesSimplex Virus1Lacking BothS-Component Origins ofDNA Synthesis (1993) (0)
- Bach 1 Deficient Mice Reduce Severity of Age-related Osteoarthritis Through the Maintenance of Autophagy and SOD 2 (2014) (0)
- Tu1941 Adoptive Transfer of Heme Oxygenase-1 Highly Expressed Macrophage Ameliorated TNBS-Induced Colitis in Mice (2012) (0)
- Posttranscriptional regulation of US11 in cells infected with a herpes simplex virus 1 recombinant lacking both 222-bp domains containing S-component origins of DNA synthesis. (1999) (0)
- [Structure and dynamics of gene regulatory network for humoral immune response]. (2011) (0)
- Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies. (2022) (0)
- Regulatory mechanism of homologous recombinational repair by RAD51 (2016) (0)
- [Combinatorial functioning of hematopoietic transcription factors and regulation of hematopoietic cell differentiation]. (1995) (0)
- S1899 Genetic Ablation of Bach1 Followed By Upregulation of Heme Oxygenase-1 Improved Nonalcoholic Steatohepatitis in Rodent Model (2008) (0)
- PS-B04-4: A NOVEL HNF4A COREPRESSOR IRF2BP2: ITS ROLE IN THE GLUCONEOGENIC GENE REGULATION VIA BIOCHEMICALLY LABILE INTERACTION (2023) (0)
- Hematopoiesis/early commitment (WS-011) Chairpersons: Toshio Kitamura, Harinder Singh (2010) (0)
- Heme Regulates Protein Interactions and Phosphorylation of BACH2 Intrinsically Disordered Region in Humoral Response (2022) (0)
- [Hematopoietic cell differentiation orchestrated by transcription factor network and its related pathogenesis]. (2018) (0)
- Transcriptional Regulation of the Bach2 B-Cell Differentiation and Apoptotic Factor by the Bcr-Abl Oncoprotein. (2005) (0)
- Abstract 1211: Gene Ablation Bach-1 Leads to Suppression of Atherosclerosis in Apolipoprotein-E (Apo-E) and Bach1 Double Knockout Mice (ApoE / Bach1 / ) (2006) (0)
- Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells. (2022) (0)
- Abstract 4807: BACH1 proline hydroxylation regulates the hypoxia response and metastasis in triple negative breast cancer (2023) (0)
- PE-317 Bach1 Is a Key-repressor of Heme Oxygenase-1 (HO-1) and Regulates Cell Proliferation(Atherosclerosis, Basic 4 (IHD) : PE54)(Poster Session (English)) (2004) (0)
- Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia (2022) (0)
- Infection perturbs Bach2- and Bach1-dependent erythroid lineage ‘choice’ to cause anemia (2018) (0)
- Correction to Supporting Information for Hayashi et.al., Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells (2018) (0)
- 841-4 Bach1 is a key-repressor of heme oxygenase-1 and regulates cell proliferation (2004) (0)
- BACH2 promotes Lineage-Specific Fate Decisions in BCR-ABL1-Driven Leukemia (2014) (0)
- Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt (2010) (0)
- Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer (2021) (0)
- Abstract A59: Bach1 is critical for transformation induced by RasV12 (2009) (0)
- IRF2BP2 is a novel HNF4α co-repressor: Its role in gluconeogenic gene regulation via biochemically labile interaction. (2022) (0)
- Aurora kinase A mediated phosphorylation of mPOU is critical for skeletal muscle differentiation (2019) (0)
- BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance (2012) (0)
- Mecom mutation related to radioulnar synostosis with amegakaryocytic thrombocytopenia reduces HSPCs in mice. (2023) (0)
- Absence of Chromatin Assembly Control Region Hypersensitive Sites in the-Globin Locus β Reconstitution of Human (2001) (0)
- The expression of methionine adenosyltransferase MAT2A is regulated through mRNA stability mediated by methyl-6-adenosine in its 3’UTR. (2016) (0)
- Ferroptosis model system by the re-expression of BACH1. (2023) (0)
- Identification of a Novel Acetyl-CoA Binding Protein (EST1) Which Epigenetically Regulates the Expression of Erythroid-Specific Genes (2008) (0)
- BACH1 DEFCIENCY AMELIORATES DEXTRAN SULPHATE SODIUM-INDUCED COLITIS IN MICE (2010) (0)
- Heme oxygenase-1 is repressed by bach1: A novel heme-binding transcriptional repressor in smooth muscle cells and macrophages (2003) (0)
- Su1901 Heme Oxygease-1 (HO-1) Prevents Intestinal Ischemia-Reperfusion Injury (IRI) Through Its Regulation of the Inflammasome (2015) (0)
- Erratum: Duodenal follicular lymphoma lacks AID but expresses BACH2 and has memory B-cell characteristics (Modern Pathology (2013) 26 (22-31) DOI: 10.1038/modpathol.2012.127) (2013) (0)
- LBODP052 A Novel Hnf4α Corepressor Irf2bp2: Its Role In The Gluconeogenic Gene Regulation Via Biochemically Labile Interaction (2022) (0)
- A DEOXYTHYMIDINE KINASE-DEFICIENT MUTANT OF E S C H E R I C H I A COLI I. ISOLATION AND SOME PROPERTIES (2002) (0)
- Microproteomics for a limited number of cells by microfluidic cell sorting and shotgun approach (2016) (0)
- S1736 The Role of BACH1 in Dextran Sodium Sulfate (DSS)-Induced Colitis in Mice (2010) (0)
- Deficiency of Bach2 results in improved tumor immunity by enhancing effector function in CD8+ T cells (2017) (0)
- Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis (2022) (0)
- Inhibition of S-Adenosylmethionine Synthesis Promotes Erythropoiesis Via Epigenetic Modifications (2021) (0)
- BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin (2022) (0)
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What Schools Are Affiliated With Kazuhiko Igarashi?
Kazuhiko Igarashi is affiliated with the following schools:
