Kazuhiko Yamamoto

Kazuhiko Yamamoto's AcademicInfluence.com Rankings

Kazuhiko Yamamoto

Medical

#2975

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#3423

Historical Rank

Rheumatology

#26

World Rank

#27

Historical Rank

medical Degrees

Kazuhiko Yamamoto

Biology

#11660

World Rank

#15072

Historical Rank

Immunology

#762

World Rank

#784

Historical Rank

Genetics

#1268

World Rank

#1370

Historical Rank

Molecular Biology

#1820

World Rank

#1849

Historical Rank

biology Degrees

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Medical
Biology

Kazuhiko Yamamoto's Degrees

PhD Genetics University of Tokyo
Doctorate Medicine University of Tokyo

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Kazuhiko Yamamoto's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetics of rheumatoid arthritis contributes to biology and drug discovery (2013) (1877)
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis (2003) (1076)
Rheumatoid arthritis (2018) (893)
Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. (2004) (761)
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab (2007) (711)
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis (2003) (618)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy (2008) (373)
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities (2005) (364)
An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor1 (2008) (314)
Inducible Expression of a Th2-Type CC Chemokine Thymus- and Activation-Regulated Chemokine by Human Bronchial Epithelial Cells1 (2000) (312)
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population (2012) (299)
Intervention of Thymus and Activation-Regulated Chemokine Attenuates the Development of Allergic Airway Inflammation and Hyperresponsiveness in Mice1 (2001) (288)
Generation of CD4+CD25+ Regulatory T Cells from Autoreactive T Cells Simultaneously with Their Negative Selection in the Thymus and from Nonautoreactive T Cells by Endogenous TCR Expression1 (2002) (285)
The Cytotoxicity of Tumor Necrosis Factor Depends on Induction of the Mitochondrial Permeability Transition* (1996) (276)
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations (2012) (264)
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility (2010) (254)
Molecular mimicry and autoimmune disease (1998) (247)
Ethnic differences in allele frequency of autoimmune-disease-associated SNPs (2005) (234)
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations (2012) (226)
A Novel Role of Hepatocyte Growth Factor as an Immune Regulator through Suppressing Dendritic Cell Function1 (2005) (226)
CD4+CD25−LAG3+ regulatory T cells controlled by the transcription factor Egr-2 (2009) (204)
Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils (2008) (201)
Expression and Function of Toll-Like Receptors in Eosinophils: Activation by Toll-Like Receptor 7 Ligand 1 (2003) (199)
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry (2016) (197)
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (2020) (191)
IL-17B and IL-17C Are Associated with TNF-α Production and Contribute to the Exacerbation of Inflammatory Arthritis1 (2007) (188)
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. (2008) (165)
Functional haplotypes of PADI 4 , encoding citrullinating enzyme peptidylarginine deiminase 4 , are associated with rheumatoid arthritis (2003) (161)
Faculty Opinions recommendation of Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance. (2010) (156)
The Family of IL-10-secreting CD4+ T cells. (2010) (150)
Expression of CXCR4 in Eosinophils: Functional Analyses and Cytokine-Mediated Regulation1 (2000) (141)
Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro (2003) (140)
Activation of transcription factor NF-κB in human synovial cells in response to tumor necrosis factor α (1996) (139)
Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases (2006) (132)
Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells. (2003) (131)
Genetics of rheumatoid arthritis: underlying evidence of ethnic differences. (2009) (127)
A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus (2007) (126)
Genetics of rheumatoid arthritis: 2018 status (2018) (125)
Multiple Loci Are Associated with White Blood Cell Phenotypes (2011) (123)
Cytokine‐mediated regulation of CXCR4 expression in human neutrophils (2002) (122)
Golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis: results of the GO-FORTH study (2011) (120)
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. (2010) (119)
Correction: Corrigendum: Regulation of histone modification and chromatin structure by the p53–PADI4 pathway (2012) (119)
Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis (2016) (118)
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population (2008) (114)
A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese (2012) (112)
Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis (2017) (112)
Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury (2018) (112)
Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese (2018) (111)
Comparison of enzymatic properties between hPADI2 and hPADI4. (2005) (110)
Citrullination by Peptidylarginine Deiminase in Rheumatoid Arthritis (2007) (106)
Molecular Mechanisms of Anti-Inflammatory Action of Erythromycin in Human Bronchial Epithelial Cells: Possible Role in the Signaling Pathway That Regulates Nuclear Factor-κB Activation (2004) (104)
Egr‐2 transcription factor is required for Blimp‐1‐mediated IL‐10 production in IL‐27‐stimulated CD4+ T cells (2013) (99)
Down-Regulation of Basophil Function by Human CD200 and Human Herpesvirus-8 CD2001 (2005) (98)
APLAR rheumatoid arthritis treatment recommendations (2015) (96)
The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population. (2010) (96)
The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression (2015) (92)
The Multicenter Study of a New Assay for Simultaneous Detection of Multiple Anti-Aminoacyl-tRNA Synthetases in Myositis and Interstitial Pneumonia (2014) (92)
Ethnogenetic heterogeneity of rheumatoid arthritis—implications for pathogenesis (2010) (91)
Roxithromycin Inhibits Cytokine Production by and Neutrophil Attachment to Human Bronchial Epithelial Cells In Vitro (1998) (91)
Chemokine receptors in human basophils: inducible expression of functional CXCR4 (2001) (91)
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. (2011) (90)
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. (2011) (90)
Functional Reconstitution of Class II MHC-Restricted T Cell Immunity Mediated by Retroviral Transfer of the αβ TCR Complex1 (2000) (89)
Longterm Safety of Tocilizumab: Results from 3 Years of Followup Postmarketing Surveillance of 5573 Patients with Rheumatoid Arthritis in Japan (2015) (89)
FCRL3, an Autoimmune Susceptibility Gene, Has Inhibitory Potential on B-Cell Receptor-Mediated Signaling1 (2009) (89)
Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study) (2016) (88)
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases (2021) (87)
TGF-β3-expressing CD4+CD25−LAG3+ regulatory T cells control humoral immune responses (2015) (87)
Influence of various hemodialysis membranes on the plasma (1→3)-β-D-glucan level (2001) (82)
Interleukin-27 in T Cell Immunity (2015) (81)
A Novel Role of Cysteinyl Leukotrienes to Promote Dendritic Cell Activation in the Antigen-Induced Immune Responses in the Lung (2004) (81)
Identification of Nine Novel Loci Associated with White Blood Cell Subtypes in a Japanese Population (2011) (80)
Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice. (2005) (80)
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences. (2004) (78)
Intracellular localization and release of eotaxin from normal eosinophils (1998) (78)
Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis. (2005) (75)
In Vivo IL-10 Gene Delivery Suppresses Airway Eosinophilia and Hyperreactivity by Down-Regulating APC Functions and Migration without Impairing the Antigen-Specific Systemic Immune Response in a Mouse Model of Allergic Airway Inflammation1 (2005) (75)
Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. (2012) (75)
Nationwide epidemiological survey of 169 patients with adult Still's disease in Japan (2015) (73)
Transcriptional Roles of CCAAT/Enhancer Binding Protein-β, Nuclear Factor-κB, and C-promoter Binding Factor 1 in Interleukin (IL)-1β-induced IL-6 Synthesis by Human Rheumatoid Fibroblast-like Synoviocytes* (1998) (71)
High Expression of IL-22 Suppresses Antigen-Induced Immune Responses and Eosinophilic Airway Inflammation via an IL-10–Associated Mechanism (2011) (70)
Chromosomal alterations among age-related haematopoietic clones in Japan (2020) (70)
Potentiation of Tumor Eradication by Adoptive Immunotherapy with T-cell Receptor Gene-Transduced T-Helper Type 1 Cells (2004) (70)
Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis (2011) (69)
Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility. (2018) (68)
Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy. (2010) (68)
Expression and Function of Toll-Like Receptors in Human Basophils (2006) (67)
Hepatocyte Growth Factor Significantly Suppresses Collagen-Induced Arthritis in Mice (2007) (66)
Roles of LAG3 and EGR2 in regulatory T cells (2012) (66)
Peptidylarginine deiminase type 4 deficiency reduced arthritis severity in a glucose-6-phosphate isomerase-induced arthritis model (2015) (66)
Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals (2018) (65)
Effects of low-dosage simvastatin on rheumatoid arthritis through reduction of Th1/Th2 and CD4/CD8 ratios (2007) (64)
Diesel exhaust particles upregulate eotaxin gene expression in human bronchial epithelial cells via nuclear factor-kappa B-dependent pathway. (2003) (64)
Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3. (2002) (64)
Anti-ribosomal P protein antibody in human systemic lupus erythematosus up-regulates the expression of proinflammatory cytokines by human peripheral blood monocytes. (2005) (63)
Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis. (2016) (63)
Humanized anti-interleukin-6-receptor antibody (tocilizumab) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomarkers, radiography, and BMI: data from the SAMURAI study (2010) (63)
Efficacy and safety of certolizumab pegol plus methotrexate in Japanese rheumatoid arthritis patients with an inadequate response to methotrexate: the J-RAPID randomized, placebo-controlled trial (2014) (60)
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. (2010) (60)
An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes. (2013) (60)
Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus (2020) (58)
Type II collagen is a target antigen of clonally expanded T cells in the synovium of patients with rheumatoid arthritis (1999) (58)
Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene. (2003) (57)
Citrullinated proteins in rheumatoid arthritis. (2005) (57)
Golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior treatment with disease-modifying antirheumatic drugs: results of the phase 2/3, multicentre, randomised, double-blind, placebo-controlled GO-MONO study through 24 weeks (2012) (57)
Pathogenesis of Sjögren's syndrome. (2003) (56)
Regulatory T-Cell-Associated Cytokines in Systemic Lupus Erythematosus (2011) (55)
Concomitant iguratimod therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: a randomized, double-blind, placebo-controlled trial (2013) (55)
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis (2010) (55)
PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population. (2013) (55)
Effect of nuclear factor-kappaB inhibition on rheumatoid fibroblast-like synoviocytes and collagen induced arthritis. (2005) (54)
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. (2011) (54)
Kidney-infiltrating CD4+ T-cell clones promote nephritis in lupus-prone mice. (2012) (54)
Genetic basis of rheumatoid arthritis: a current review. (2014) (54)
Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese (2012) (53)
Platelet activation markers overexpressed specifically in patients with aspirin-exacerbated respiratory disease. (2016) (52)
Efficacy and safety of certolizumab pegol without methotrexate co-administration in Japanese patients with active rheumatoid arthritis: The HIKARI randomized, placebo-controlled trial (2014) (51)
PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression (2013) (49)
Safety and efficacy of combination therapy of iguratimod with methotrexate for patients with active rheumatoid arthritis with an inadequate response to methotrexate: An open-label extension of a randomized, double-blind, placebo-controlled trial (2014) (49)
IFN-γ Attenuates Antigen-Induced Overall Immune Response in the Airway As a Th1-Type Immune Regulatory Cytokine1 (2009) (48)
Role of TGF-β3 in the regulation of immune responses. (2015) (47)
Antiinflammatory effect of simvastatin in patients with rheumatoid arthritis. (2002) (47)
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice (2016) (46)
Genetics of rheumatoid arthritis in Asia—present and future (2015) (46)
Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus. (2010) (46)
Gene Therapy of Arthritis with TCR Isolated from the Inflamed Paw1 (2006) (46)
Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production (2016) (45)
Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation (2014) (45)
A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs (2009) (43)
A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects (2011) (42)
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis (2017) (41)
A two-way interaction between hepatocyte growth factor and interleukin-6 in tissue invasion of lung cancer cell line. (2002) (41)
Mechanisms of Disease: genetics of rheumatoid arthritis—ethnic differences in disease-associated genes (2007) (41)
From genetics to functional insights into rheumatoid arthritis. (2015) (40)
Reconstitution of CD8+ T Cells by Retroviral Transfer of the TCR αβ-Chain Genes Isolated from a Clonally Expanded P815-Infiltrating Lymphocyte1 (2003) (40)
Tocilizumab discontinuation after attaining remission in patients with rheumatoid arthritis who were treated with tocilizumab alone or in combination with methotrexate: results from a prospective randomised controlled study (the second year of the SURPRISE study) (2018) (40)
Regulation of mouse mast cell surface FcεRI expression by dexamethasone (2001) (39)
Neuromyelitis optica spectrum disorder complicated with Sjogren syndrome successfully treated with tocilizumab: A case report (2016) (39)
Insight from genome‐wide association studies in rheumatoid arthritis and multiple sclerosis (2011) (39)
Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease1 (2004) (39)
Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis (2013) (39)
5-Lipoxygenase products regulate basophil functions: 5-Oxo-ETE elicits migration, and leukotriene B(4) induces degranulation. (2005) (39)
Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis (2018) (39)
Early Interleukin 4–Dependent Response Can Induce Airway Hyperreactivity before Development of Airway Inflammation in a Mouse Model of Asthma (2001) (38)
Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization. (2008) (37)
Quantitative and qualitative characterization of expanded CD4+ T cell clones in rheumatoid arthritis patients (2015) (37)
Accumulation of Common T Cell Clonotypes in the Salivary Glands of Patients with Human T Lymphotropic Virus Type I-Associated and Idiopathic Sjögren’s Syndrome1 (2000) (37)
Regulation of Chemokine Receptor Expression in Eosinophils (2001) (37)
Antigen-Specific T Cells Transduced with IL-10 Ameliorate Experimentally Induced Arthritis Without Impairing the Systemic Immune Response to the Antigen1 (2000) (36)
Comparative effects of basophil-directed growth factors. (2003) (36)
Flexible positive airway pressure improves treatment adherence compared with auto-adjusting PAP. (2012) (35)
A Functional Study on CysLT1 Receptors in Human Eosinophils (2002) (35)
IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors (2018) (35)
Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4+ T cells, and disease activity (2016) (35)
Peyer's Patch Dendritic Cells Capturing Oral Antigen Interact with Antigen‐Specific T Cells and Induce Gut‐Homing CD4+CD25+ Regulatory T Cells in Peyer's Patches (2004) (34)
ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese (2012) (34)
B cell epitope on the U1 snRNP‐C autoantigen contains a sequence similar to that of the herpes simplex virus protein (1993) (34)
Changing expression of IL-3 and IL-5 receptors in cultured human eosinophils. (2003) (33)
Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis. (2006) (33)
Regulatory cell subsets in the control of autoantibody production related to systemic autoimmunity (2012) (33)
Efficacy and safety of rituximab in Japanese patients with systemic lupus erythematosus and lupus nephritis who are refractory to conventional therapy (2015) (33)
Lnk/Sh2b3 Controls the Production and Function of Dendritic Cells and Regulates the Induction of IFN-γ–Producing T Cells (2014) (33)
Three cases of ortho-phthalaldehyde-induced anaphylaxis after laryngoscopy: detection of specific IgE in serum. (2007) (32)
Integration of genetics and miRNA–target gene network identified disease biology implicated in tissue specificity (2018) (32)
Noninvasive system for evaluating allergen-induced nasal hypersensitivity in murine allergic rhinitis (2006) (32)
Transendothelial Migration of Human Basophils1 (2004) (32)
Metabolism as a key regulator in the pathogenesis of systemic lupus erythematosus. (2019) (32)
Enhanced expression of CD69 and CD25 antigen on human peripheral blood mononuclear cells by prolactin. (2005) (31)
Variations in the human Th2-specific chemokine TARC gene (2003) (30)
Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis (2013) (30)
Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis (2017) (30)
Efficacy of intensive immunosuppression in exacerbated rheumatoid arthritis-associated interstitial lung disease (2017) (30)
IgE- and FcεRI-mediated migration of human basophils (2005) (30)
Regulation of Human Eotaxin Generation by Th1-/Th2-Derived Cytokines (2000) (30)
Regulatory T Cell-Mediated Control of Autoantibody-Induced Inflammation (2012) (29)
The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation. (2016) (28)
An alternatively spliced form of the human CD94 gene (1998) (28)
Sustainable Efficacy of Switching From Intravenous to Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis (2015) (28)
Splenic Dendritic Cells Induced by Oral Antigen Administration Are Important for the Transfer of Oral Tolerance in an Experimental Model of Asthma (2006) (28)
Long term persistent accumulation of CD8+ T cells in synovial fluid of rheumatoid arthritis (1997) (28)
Nationwide prospective and retrospective surveys for hepatitis B virus reactivation during immunosuppressive therapies (2016) (28)
HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis (2009) (28)
Autoantigen BiP‐Derived HLA–DR4 Epitopes Differentially Recognized by Effector and Regulatory T Cells in Rheumatoid Arthritis (2015) (27)
A tetrodotoxin-binding protein in the hemolymph of shore crab Hemigrapsus sanguineus: purification and properties. (2002) (27)
A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population (2008) (27)
Safety and effectiveness of iguratimod in patients with rheumatoid arthritis: Final report of a 52-week, multicenter postmarketing surveillance study (2019) (27)
Prolonged Allergen Challenge in Murine Nasal Allergic Rhinitis: Nasal Airway Remodeling and Adaptation of Nasal Airway Responsiveness (2007) (27)
Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians (2019) (27)
Inward rectifier K(+) current in human bronchial smooth muscle cells: inhibition with antisense oligonucleotides targeted to Kir2.1 mRNA. (2002) (26)
Interferon- γ Inhibits Hepatocyte Growth Factor-Stimulated Cell Proliferation of Human Bronchial Epithelial Cells (2002) (26)
Early Growth Response Gene 2-Expressing CD4+LAG3+ Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases (2018) (26)
Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs—a multicenter, double-blind, parallel-group trial (2011) (26)
Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation: 2-year results of the C-OPERA study, a phase III randomised trial (2017) (26)
Tocilizumab-induced leucocytoclastic vasculitis in a patient with rheumatoid arthritis. (2014) (26)
Antigen-sensitized CD4+CD62Llow memory/effector T helper 2 cells can induce airway hyperresponsiveness in an antigen free setting (2005) (26)
Genetic studies of rheumatoid arthritis (2015) (26)
Aire downregulates multiple molecules that have contradicting immune-enhancing and immune-suppressive functions. (2004) (26)
SLC22A4 and RUNX1: identification of RA susceptible genes (2004) (26)
T-cell-mediated immunity in thyroid-associated ophthalmopathy. (2002) (25)
IL-5-Induced Hypereosinophilia Suppresses the Antigen-Induced Immune Response via a TGF-β-Dependent Mechanism1 (2007) (25)
Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4+ T cells (2009) (25)
Care for patients with rheumatic diseases during COVID‐19 pandemic: A position statement from APLAR (2020) (24)
Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis (2019) (24)
Suppression of T cell responses by chondromodulin I, a cartilage-derived angiogenesis inhibitory factor: therapeutic potential in rheumatoid arthritis. (2004) (24)
Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population (2015) (24)
Immediate noninvasive ventilation may improve mortality in patients with hepatopulmonary syndrome after liver transplantation (2011) (24)
PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes (2019) (23)
Colnal prevalence of T cells infiltrating into the pancreas of prediabetic non-obese diabetic mice (1996) (23)
Dissection of the role of MHC class II A and E genes in autoimmune susceptibility in murine lupus models with intragenic recombination. (2004) (23)
Emerging roles of Egr2 and Egr3 in the control of systemic autoimmunity. (2016) (23)
A case of refractory polyarteritis nodosa successfully treated with rituximab (2017) (23)
Interferon-gamma inhibits hepatocyte growth factor-stimulated cell proliferation of human bronchial epithelial cells: upregulation of p27(kip1) cyclin-dependent kinase inhibitor. (2002) (23)
Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1. (2009) (23)
Immune responses to Mycobacterial heat shock protein 70 accompany self-reactivity to human BiP in rheumatoid arthritis (2016) (23)
IgG4‐related disease (2016) (22)
Egr2 and Egr3 are the unique regulators for systemic autoimmunity (2013) (22)
Eight novel susceptibility loci and putative causal variants in atopic dermatitis. (2021) (22)
Transcriptome analysis of peripheral blood from patients with rheumatoid arthritis: a systematic review (2018) (22)
Comparison of the Jβ gene usage among different T cell receptor Vβ families in spleens of C57BL/6 mice (1994) (22)
Downregulation of IL-12 and a novel negative feedback system mediated by CD25+CD4+ T cells. (2005) (22)
Induction of Basophil Desensitization in Physiological Medium: Enhancement after IgE-Dependent Upregulation of Surface IgE Binding on Basophils (2003) (22)
Splenic Phagocytes Promote Responses to Nucleosomes in (NZB × NZW) F1 Mice1 (2008) (22)
A case of pulmonary veno‐occlusive disease associated with systemic sclerosis (2003) (21)
Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes (2006) (21)
Ortho-phthalaldehyde-induced anaphylaxis after laryngoscopy. (2006) (20)
Reconstitution of CD8+ T cells by retroviral transfer of the TCR alpha beta-chain genes isolated from a clonally expanded P815-infiltrating lymphocyte. (2003) (20)
A gene module associated with dysregulated TCR signaling pathways in CD4+ T cell subsets in rheumatoid arthritis. (2017) (20)
Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis (2005) (20)
Anti-CD69 Autoantibodies Cross-React with Low Density Lipoprotein Receptor-Related Protein 2 in Systemic Autoimmune Diseases1 (2001) (20)
Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells. (2004) (20)
TGF-β3 Inhibits Antibody Production by Human B Cells (2017) (20)
Trans-basement membrane migration of human basophils: role of matrix metalloproteinase-9. (2006) (20)
HLA-DRB1 Shared Epitope Alleles and Disease Activity Are Correlated with Reduced T Cell Receptor Repertoire Diversity in CD4+ T Cells in Rheumatoid Arthritis (2018) (20)
Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo. (2002) (20)
Macrophage activation syndrome associated with tocilizumab treatment in adult-onset Still’s disease (2017) (19)
Transcription Factor Early Growth Response 3 Is Associated with the TGF-β1 Expression and the Regulatory Activity of CD4-Positive T Cells In Vivo (2013) (19)
Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC) (2018) (19)
SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis. (2008) (19)
Overview of LAG-3-Expressing, IL-10-Producing Regulatory T Cells. (2017) (19)
Time course analysis of α+β+ T cell clones during normal pregnancy (1996) (19)
Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population (2019) (18)
Peripheral Tolerance to a Nuclear Autoantigen: Dendritic Cells Expressing a Nuclear Autoantigen Lead to Persistent Anergic State of CD4+ Autoreactive T Cells After Proliferation1 (2002) (18)
Faculty Opinions recommendation of Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. (2009) (18)
An Association Between Amino Acid Position 74 of HLA–DRB1 and Anti–Citrullinated Protein Antibody Levels in Japanese Patients With Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis (2015) (18)
Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study (2015) (17)
Eosinophil Degranulation in the Presence of Lung Fibroblasts (1998) (17)
Lessons from a genomewide association study of rheumatoid arthritis. (2007) (17)
Wegener's granulomatosis with eosinophilia. (2005) (17)
The effects of TGF-βs on immune responses. (2016) (17)
Characteristics of granulomatosis with polyangiitis patients in Japan (2015) (17)
Clinical efficacy, radiographic progression, and safety through 156 weeks of therapy with subcutaneous golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis despite prior methotrexate therapy: final results of the randomized GO-FORTH trial (2015) (17)
Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis. (2005) (16)
T cells accumulating in the inflamed joints of a spontaneous murine model of rheumatoid arthritis become restricted to common clonotypes during disease progression. (2004) (16)
Identification of citrullinated cellular fibronectin in synovial fluid from patients with rheumatoid arthritis (2014) (16)
Regulation of Surface FcεRI Expression on Human Eosinophils by IL-4 and IgE (2001) (16)
A case of osteoarthropathy due to Erdheim-Chester disease with overlapping Langerhans' cell infiltration. (2010) (16)
Reevaluation of Pluripotent Cytokine TGF-β3 in Immunity (2018) (16)
Alendronate Attenuates Eosinophilic Airway Inflammation Associated with Suppression of Th2 Cytokines, Th17 Cytokines, and Eotaxin-2 (2013) (15)
Case report: streptomycin-induced anaphylactic shock during oocyte retrieval procedures for in vitro fertilization. (2002) (15)
Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis. (2020) (15)
Evaluation of microsatellite markers in association studies: a search for an immune-related susceptibility gene in sarcoidosis (2005) (15)
Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1+CXCR5−/dim B-helper T cell induction (2017) (15)
Human thymoproteasome variations influence CD8 T cell selection (2017) (15)
IgE- and FcεRI-Mediated Enhancement of Surface CD69 Expression in Basophils: Role of Low-Level Stimulation (2007) (15)
Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis (2019) (14)
A Case of Polymyxin b-Immobilized Fiber Column Treatment for Rapidly Progressive Interstitial Pneumonia Associated with Clinically Amyopathic Dermatomyositis (2013) (14)
Identification of tonsillar CD4+CD25-LAG3+ T cells as naturally occurring IL-10-producing regulatory T cells in human lymphoid tissue. (2017) (14)
CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity (2019) (14)
POSH promotes cell survival in Drosophila and in human RASF cells (2010) (14)
Intratracheal Delivery of Hepatocyte Growth Factor Directly Attenuates Allergic Airway Inflammation in Mice (2009) (14)
Pretreatment with Low Levels of FcεRI-Crosslinking Stimulation Enhances Basophil Mediator Release (2013) (14)
Membranous nephropathy with repeated flares in IgG4-related disease (2013) (14)
Early response to certolizumab pegol predicts long-term outcomes in patients with active rheumatoid arthritis: results from the Japanese studies (2015) (13)
The gene encoding the Ia-Associated invariant chain is located on chromosome 18 in the mouse (2004) (13)
Eldecalcitol is superior to alfacalcidol in maintaining bone mineral density in glucocorticoid-induced osteoporosis patients (e-GLORIA) (2020) (13)
Upregulation of Lung Dendritic Cell Functions in Elastase-Induced Emphysema (2009) (13)
Antigen-specific regulatory T cells are detected in Peyer's patches after the interaction between T cells and dendritic cells loaded with orally administered antigen. (2011) (12)
First external validation of sensitivity and specificity of the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) classification criteria for idiopathic inflammatory myopathies with a Japanese cohort (2019) (12)
Effect of cadmium (CdCl2) on cell proliferation and production of EDRF (endothelium-derived relaxing factor) by cultured human umbilical arterial endothelial cells (2009) (12)
Obstacles to the implementation of the treat-to-target strategy for rheumatoid arthritis in clinical practice in Japan (2015) (12)
Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling (2019) (12)
Long-term efficacy and safety of certolizumab pegol in Japanese rheumatoid arthritis patients with an inadequate response to methotrexate: 52-week results from an open-label extension of the J-RAPID study (2014) (11)
Long-term efficacy and safety of certolizumab pegol in Japanese rheumatoid arthritis patients who could not receive methotrexate: 52-week results from an open-label extension of the HIKARI study (2014) (11)
Accumulation of Common Clonal T Cells in Multiple Lesions of Sarcoidosis (2000) (11)
Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice (2020) (11)
Therapeutic potential of regulatory cytokines that target B cells. (2016) (11)
Myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis with diffuse tubulointerstitial nephritis. (2009) (10)
Effects of hachimi-jio-gan (ba-wei-di-huang-wan) on blood flow in the human central retinal artery. (2003) (10)
Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL 6 locus (2011) (10)
Tracheobronchitis with dyspnea in a patient with ulcerative colitis. (2015) (10)
Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling (2015) (10)
Clonal dynamics of tumor‐infiltrating lymphocytes (2005) (10)
Linking of genetic risk variants to disease-specific gene expression via multi-omics studies in rheumatoid arthritis. (2019) (10)
Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis (2021) (10)
Perillyl alcohol suppresses antigen-induced immune responses in the lung. (2014) (10)
Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus (2022) (10)
Expression of MHC class I molecules together with antigenic peptides on filamentous phages. (2002) (10)
T-cell clonotypes specific for Dermatophagoides pteronyssinus in the skin lesions of patients with atopic dermatitis. (2002) (10)
An efficient method to prepare T cell receptor gene‐transduced cytotoxic T lymphocytes type 1 applicable to tumor gene cell‐therapy (2003) (10)
Post-hoc analysis showing better clinical response with the loading dose of certolizumab pegol in Japanese patients with active rheumatoid arthritis (2015) (9)
Prevalence of primary Sjögren’s syndrome in patients undergoing evaluation for pulmonary arterial hypertension (2018) (9)
Cholinergic-drug induced sicca syndrome in Parkinson’s disease: a case report and a review of the literature (1999) (9)
Distinct transcriptome architectures underlying lupus establishment and exacerbation (2022) (9)
Regulatory polymorphisms in EGR 2 are associated with susceptibility to systemic lupus erythematosus (2010) (9)
Enhancement of basophil apoptosis by olopatadine and theophylline. (2008) (9)
Shared genetic factors and their causality in autoimmune diseases (2019) (9)
Blocking Antibody Is Generated in Allergic Rhinitis Patients during Specific Immunotherapy Using Standardized Japanese Cedar Pollen Extract (2008) (8)
Prevention of joint destruction by tacrolimus in patients with early rheumatoid arthritis: a post hoc analysis of a double-blind, randomized, placebo-controlled study (2012) (8)
Cardiopulmonary Arrest After Severe Anaphylactic Reaction to Second Infusion of Infliximab in a Patient with Ankylosing Spondylitis (2011) (8)
Strategic Outlook toward 2030: Japan's research for allergy and immunology - Secondary publication. (2020) (7)
Long-term therapeutic effects and safety of tacrolimus added to methotrexate in patients with rheumatoid arthritis (2013) (7)
Thrombotic thrombocytopenic purpura with severe hypertension in a patient with systemic sclerosis sine scleroderma and polymyositis. (2011) (7)
IgE- and FcepsilonRI-mediated enhancement of surface CD69 expression in basophils: role of low-level stimulation. (2007) (7)
Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells (2018) (7)
Rheumatology in East Asia (2018) (7)
Six years’ accomplishment of the Initiative on Rare and Undiagnosed Diseases: nationwide project in Japan to discover causes, mechanisms, and cures (2022) (7)
Association of EMCN with Susceptibility to Rheumatoid Arthritis in a Japanese Population (2011) (7)
Profiling of transcribed cis-regulatory elements in single cells (2021) (6)
Tuberculous pleurisy diagnosed by medical thoracoscopy in an adalimumab-treated rheumatoid arthritis patient after treatment of latent tuberculosis infection (2013) (6)
Clinical efficacy, radiographic, and safety results of golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior therapy with disease-modifying antirheumatic drugs: Final results of the GO-MONO trial through week 120 (2018) (6)
Severe airflow limitation in two patients with systemic lupus erythematosus: effect of inhalation of anticholinergics (2008) (6)
Massive calcinosis cutis associated with primary Sjögren’s syndrome (2016) (6)
Antigen-specific immunotherapy for autoimmune diseases (2007) (6)
Association of methotrexate use and lymphoproliferative disorder in patients with rheumatoid arthritis: results from a Japanese multi-institutional retrospective study. (2021) (6)
Genetics of human autoimmunity: From genetic information to functional insights. (2017) (6)
A new T‐cell activation mode for suboptimal doses of antigen under the full activation of T cells with different specificity (2015) (6)
Functional genomics of autoimmune diseases (2021) (6)
Ethnically shared and heterogeneous impacts of molecular pathways suggested by the genome-wide meta-analysis of rheumatoid arthritis. (2016) (5)
A Rapid and Simple Photometric Assay for Quantification of Eosinophil Chemotaxis (2000) (5)
[A case of eosinophilic lung disease presenting asthma-like symptoms and centrilobular shadows in both lung fields]. (2003) (5)
Identifying the most influential gene expression profile in distinguishing ANCA-associated vasculitis from healthy controls. (2021) (5)
Analysis of basophil activation in patients with aspirin-exacerbated respiratory disease. (2017) (5)
Polymorphic lymphoproliferative disorders in patients with rheumatoid arthritis are associated with a better clinical outcome (2018) (5)
Prevention of joint destruction in patients with high disease activity or high C-reactive protein levels: Post hoc analysis of the GO-FORTH study (2016) (5)
T Cell Receptor Gene Therapy for Autoimmune Diseases (2007) (5)
Predictive Factors for Reintubation following Noninvasive Ventilation in Patients with Respiratory Complications after Living Donor Liver Transplantation (2013) (5)
Synovial Mononuclear Cells Consist with T Cells Which Produce High Levels of Tumor Necrosis Factor α (1997) (4)
CD4+CD25-LAG-3+ T cells in mouse and human. (2010) (4)
Analysis of accumulating clonotypes of T cell in joints of a spontaneous murine model of rheumatoid arthritis. (2004) (4)
Sinus bradycardia after intravenous pulse methylprednisolone therapy in patients with systemic lupus erythematosus (2019) (4)
IgE- and FcepsilonRI-mediated migration of human basophils. (2005) (4)
The power Doppler twinkling artefact associated with periarticular calcification induced by intra-articular corticosteroid injection in patients with rheumatoid arthritis (2013) (4)
Clonal identities and multiple isotype transcripts in hematological diseases revealed by a single‐strand conformation polymorphism analysis of the immunoglobulin heavy chain messenger signals (1999) (4)
[STRATEGIC OUTLOOK TOWARD 2030: JAPAN'S RESEARCH FOR ALLERGY AND IMMUNOLOGY]. (2020) (4)
Acupuncture and Moxibustion Treatment for Rheumatoid Arthritis-Multi-Center Randomized Controlled Trial of Acupuncture and Moxibustion for Rheumatoid Arthritis-. (2003) (3)
T-cell receptor- and anti-inflammatory gene-modulated T cells as therapy for autoimmune disease (2007) (3)
Acupuncture Treatment for Peripheral Facial Paralysis. (2002) (3)
Faculty Opinions recommendation of Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. (2009) (3)
Two Cases of Gouty Sacroiliitis Evaluated by Dual-energy Computed Tomography (2016) (3)
Contribution of the T cell receptor BJ gene to recognition of the P91A tumor antigen in DBA/2 mice (1998) (3)
[New therapeutic strategy of rheumatoid arthritis to reach the goal of suppression of joint destruction]. (2007) (3)
Clonal accumulation of T cells in early lesions of Crohn's disease (1995) (3)
Enhanced gut homing receptor expression of unswitched memory B cells in rheumatoid arthritis. (2017) (3)
Introduction: Autoimmunity Special Issue. (2016) (3)
Decreased peripheral blood memory B cells are associated with the presence of interstitial lung disease in rheumatoid arthritis: a case-control study (2020) (3)
Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population (2017) (3)
Minodronate combined with alfacalcidol versus alfacalcidol alone for glucocorticoid-induced osteoporosis: a multicenter, randomized, comparative study (2020) (3)
[Toward therapeutic application of IL-10-producing regulatory T cells]. (2013) (3)
Predictive value of serum amyloid a levels for requirement of concomitant methotrexate in tocilizumab initiation: A post hoc analysis of the SURPRISE study (2020) (3)
I-A homologous antigen on human lymphocytes detected by a monoclonal antibody (2004) (3)
Regulatory T cells in the control of T cell homeostasis (2010) (3)
Streptomycin-induced anaphylactic shock during oocyte retrieval procedures for in vitro fertilization (2002) (2)
[Acute exacerbation of interstitial pneumonia associated with active systemic lupus erythematosus in a patient with rheumatoid arthritis]. (2002) (2)
Mice Inflammation and Hyperresponsiveness in the Development of Allergic Airway Activation-Regulated Chemokine Attenuates Intervention of Thymus and Yamamoto and Kouji (2001) (2)
The genomic landscape of clonal hematopoiesis in Japan (2019) (2)
Two cases of very elderly onset male lupus patient; the characteristics and sex differences of elderly onset systemic lupus erythematosus patients (2017) (2)
Synovial fibroblasts contribute to the genetic risk of rheumatoid arthritis through the synergistic action of cytokines (2019) (2)
Anti–Double‐Stranded DNA Antibodies Recognize DNA Presented on HLA Class II Molecules of Systemic Lupus Erythematosus Risk Alleles (2021) (2)
[Basic research overview in rheumatoid arthritis]. (2016) (2)
Mechanisms of Autoimmunity (2004) (2)
A Clinical Study of Acupuncture Therapy for Lumbar Spinal Canal Stenosis. (1999) (2)
Increased concentration of serum soluble LAG3 in systemic lupus erythematosus (2012) (2)
Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus (2021) (2)
CD4+CD25−LAG3+ regulatory T cells in humoral immunity (2019) (2)
An elderly woman with peripheral spondyloarthritis with aortitis (2012) (2)
Thoracic intradural extramedullary lesions causing progressive myelopathy as an initial manifestation of granulomatosis with polyangiitis: a case report and review of literature (2017) (2)
[Peptidylarginine deiminase type4 (PADI4) role in immune system]. (2014) (2)
[Genetic analyses of rheumatoid arthritis]. (2013) (2)
[The functions of CD4+CD25-LAG3+ regulatory T cells and Egr2 in the regulation of autoimmunity]. (2014) (2)
Efficacy of combination therapy with tacrolimus and mizoribine for cyclophosphamide‐resistant ANCA‐associated glomerulonephritis (2017) (2)
[Recent advances in the pathogenesis of rheumatoid arthritis]. (2009) (2)
P-Selectin is a Key Molecule Underlying the Pathophysiology of Aspirin- Exacerbated Respiratory Disease (2016) (2)
Reduction of CD83 Expression on B Cells and the Genetic Basis for Rheumatoid Arthritis: Comment on the Article by Thalayasingam et al (2018) (2)
Establishment of L-3,4-Dihydroxyphenilalaninde-induced pharmacological dementia model mouse (2001) (2)
Urinary phagocytic macrophages in hemophagocytic lymphohistiocytosis. (2016) (2)
Functional genetics for studying the human immune system. (2021) (2)
[Molecular pathogenesis of rheumatoid arthritis--the roles of synovial cells, immune cells, and pro-inflammatory cytokines]. (2007) (2)
Investigation of the pathogenesis of autoimmune diseases by iPS cells. (2017) (2)
Differential modulation of human basophil functions through PGD2 receptors DP and CRTH2/DP2 (2004) (2)
Meta-analysis of 208,370 East Asians identifies 113 genomic loci and yields new non-immune cell relevant biological insights for systemic lupus erythematosus (2020) (1)
Factors associated with successful discontinuation of certolizumab pegol in early rheumatoid arthritis (2020) (1)
Citrulline and anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis (2006) (1)
[Case report: a case of adult-onset Still's disease with thrombotic microangiopathy-like disorder successfully treated by plasma exchange and anti-TNF therapy]. (2011) (1)
THU0225 INTEGRATIVE PLASMA METABOLOME AND TRANSCRIPTOME ANALYSIS REVEALED THE IMPORTANCE OF HISTIDINE HOMEOSTASIS IN SLE PATHOGENESIS WITH POTENTIAL FOR IMPROVED SLE PATIENTS STRATIFICATION (2020) (1)
Unilateral proptosis in a woman with asthma (2015) (1)
Components of Hachimi-jio-gan (Ba-Wei-Di-Huang-Wan) and changes in blood flow in the human central retinal artery (2002) (1)
[Genetic factors of rheumatoid arthritis]. (2015) (1)
Association of methotrexate use and lymphoproliferative disorder in patients with rheumatoid arthritis: Results from a Japanese multi-institutional retrospective study. (2021) (1)
The genetics of systemic lupus erythematosus: differences across ethnicities (2006) (1)
The Asia-Pacific Initiative for Rheumatology Nurse Education: Current gaps, programme development and future outlook. (2020) (1)
188 Dexamethasone decreases the levels of surface FcϵRI expression in mouse mast cells (2000) (1)
Morning granulocytopenia in two patients with connective-tissue disease treated with oral corticosteroids (2011) (1)
[Analysis of the change in clonotypes of T cells accumulated in 4 feet joints of SKG mice]. (2004) (1)
A1.29 In rheumatoid arthritis, smoking is not primarily associated with anti-citrullinaged protein antibodies, but with the presence of several autoantibodies (2014) (1)
[Regulatory T cells in systemic lupus erythematosus]. (2015) (1)
Autotaxin is a Potential Link between Genetic Risk Factors and Pathogenesis of Systematic Lupus Erythematosus in Plasmacytoid Dendritic Cells (2022) (1)
Combined plasma metabolomic and transcriptomic analysis identify histidine as a biomarker and potential contributor in SLE pathogenesis. (2022) (1)
The metabolic regulation in immune cells and pathogenesis of systemic lupus erythematosus ∼toward new therapeutic applications∼. (2017) (1)
Contents, Vol. 94, 1991 (1991) (1)
Development of systemic lupus erythematosus in an elderly male hemodialysis patient with pleuritis (2013) (1)
Iguratimod-induced acute interstitial pneumonia with hypogammaglobulinemia in a rheumatoid arthritis patient (2017) (1)
Th 1-Type Immune Regulatory Cytokine Immune Response in the Airway As a Attenuates Antigen-Induced Overall (2009) (1)
Faculty Opinions recommendation of Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. (2009) (1)
Dysregulation of the gene signature of effector regulatory T cells in the early phase of systemic sclerosis. (2022) (1)
Disruptive innovation in rheumatology: new networks of global public–private partnerships are needed to take advantage of scientific progress (2020) (1)
JAK inhibition and modulation of T cell function (2013) (1)
[Discussion meeting on treatment of rheumatoid arthritis with biologics and their side effects]. (2011) (1)
Rheumatoid arthritis heritability is concentrated in regulatory elements with CD4+ T cell-state-specific transcription factor binding profiles (2018) (1)
Effect of B cell depletion using peptide tetramers in collagen-induced arthritis (2012) (1)
[Progress on diagnostic tests for rheumatoid arthritis]. (2008) (1)
Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s syndrome (2022) (1)
Two Cases of Acupuncture Treatment for Lumbar Spinal Canal Stenosis Due to Hemodialysis-related Spondyloarthropathy (2003) (1)
T CELL CLONALITY AND TRANSPLANTATION. (1995) (0)
Epitope Progression in Autoantibody Production Suggested by Epitope Mappings of SS-B/La and U 2snRNP B″Protein (1989) (0)
Critical Role Of T Follicular-helper Cells In B Cell Autoimmunity During Lymphopenia (2012) (0)
Eotaxin-2 Th 2 Cytokines , Th 17 Cytokines , and ofInflammation Associated with Suppression Alendronate Attenuates Eosinophilic Airway Yamamoto (2013) (0)
Nucleosomes in (NZB × NZW) F1 Mice Splenic Phagocytes Promote Responses to (2013) (0)
Mammalian expression of single chain variable region fragments dimerized by Fc regions (2005) (0)
[New concept on diagnosis and therapy for rheumatoid and collagen diseases (discussion)]. (2007) (0)
Subject Index Vol. 149, Suppl. 1, 2009 (2009) (0)
IL-3-Primed Basophils Secretory IgA Induces Degranulation of (2013) (0)
[111th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium; 1. Immunity and diseases in internal medicine--Frontier of pathophysiology and treatment; 1) Pathogeneses of autoimmune diseases: an overview]. (2014) (0)
ReceptorHuman Basophil Activation via Its ST2 An IL-1 Cytokine Member, IL-33, Induces (2008) (0)
Comparative effects of IL-3, IL-5, and GM-CSF on human basophils and eosinophils (2003) (0)
T Cells in Autoimmune Disorders (2002) (0)
Subject Index Vol. 122, Suppl. 1, 2000 (2000) (0)
Title Decreased severity of experimental autoimmune arthritis inpeptidylarginine deiminase type 4 knockout mice (2018) (0)
Activation markers for human basophils (2002) (0)
Comparison of toll-like receptor expression in eosinophils, basophils, and neutrophils* (2003) (0)
Faculty Opinions recommendation of Citrullination regulates pluripotency and histone H1 binding to chromatin. (2014) (0)
Epitope Mapping of the Recombinant Human U1snRNP 68 k Protein (1989) (0)
Synovial Bursa Protruding Through the Triceps Brachii Muscle (2014) (0)
Advanced on medical care of autoimmune disease and allergosis. Allergosis. Recent knowledge on the mechanism of the allergy. (1998) (0)
MSRV IN JAPANESE PATIENTS WITH MULTIPLE SCLEROSIS. (1999) (0)
After Proliferation Autoreactive T Cells + Anergic State of CD4 Nuclear Autoantigen Lead to Persistent Autoantigen: Dendritic Cells Expressing a Peripheral Tolerance to a Nuclear (2002) (0)
[Overview: application of DNA chips to clinical immunology]. (2005) (0)
Molecular Mechanisms of Autoimmune Diseases (2014) (0)
Autoreactive T cells as a therapeutic vehicle (1999) (0)
Functional Analyses and Cytokine-Mediated Expression of CXCR 4 in Eosinophils : Morita and Koichi (2000) (0)
Biographical Sketch of Dr. Alec H. Sehon (1991) (0)
Subject Index Vol. 161, Suppl. 2, 2013 (2013) (0)
The 10th International Rheumatology Symposium in Tokyo "2001 Frontier of Rheumatology" (2001) (0)
Effect of Toll-like receptor ligands on survival of human bronchial epithelial cells (2005) (0)
[Genomic approaches to bone and joint diseases. Current status of human disease genomics in rheumatoid arthritis]. (2008) (0)
[Studies on the genes related to rheumatoid arthritis and the application of the results to clinical medicine]. (2007) (0)
Faculty Opinions recommendation of Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. (2013) (0)
Eosinophils in allergy and related diseases. Proceedings of a workshop. Tokyo, Japan. June 21, 2008. (2009) (0)
A splice acceptor site mutation of the TAP1 gene in HLA class Ideficient patient (1998) (0)
[Classification and diagnosis of rheumatoid arthritis]. (2005) (0)
Mice Suppresses Collagen-Induced Arthritis in Hepatocyte Growth Factor Significantly (2007) (0)
Forefront of medicine and medical treatment.Molecular homology and autoimmunity. (1991) (0)
Suppress a Systemic Autoimmune Disease Engineered by Triple Gene Transfer Nucleosome-Specific Regulatory T Cells (2004) (0)
Refractory RA; Diagnosis and Treatment - Prospect toword the Future (1999) (0)
Faculty Opinions recommendation of Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation. (2014) (0)
0192-0561(95)00102-6 A NEW ASSAY SYSTEM DETECTING ANTIBODY PRODUCTION AND DELAYED-TYPE HYPERSENSITIVITY RESPONSES TO TR/NITROPHENYL HAPTEN IN AN INDIVIDUAL MOUSE (1996) (0)
Eosinophil Activation by Prostaglandin D2 and Its Modulation by Seratrodast (2001) (0)
An investigation of incidental hypouricemia (1991) (0)
Antigen Processing Mechanisms in Antigen Presenting Cells. (1992) (0)
Characterization of a Monoclonal Antibody Reacting with a Neutral Glycolipid That Is Associated with Human T-Cell Leukemia Virus Type I Infection and Freshly Isolated Adult T-Cell Leukemia 1 (2006) (0)
Genetics and functional genetics of autoimmune diseases (2022) (0)
448 Expression and function of CXCR4 in eosinophils (2000) (0)
[Rheumatoid arthritis and interleukin-32]. (2007) (0)
Role of DC and chemokines for the induction of gut-homing CD4^+CD25^+ regulatory T cells in Peyer's patches (2003) (0)
[Prospect for the 21st century: allergic collagen diseases]. (2002) (0)
Molecular analyses of autoepitopes on nuclear antigens (1991) (0)
[Diagnosis, physiopathology, and treatment of collagen diseases of the aged]. (2003) (0)
[Genetics of autoimmune and collagen diseases]. (2009) (0)
Subject Index Vol. 143, Suppl. 1, 2007 (2007) (0)
HIKARI trial of certolizumab pegol 557 (2018) (0)
Receptor-Mediated Signaling Has Inhibitory Potential on B-Cell FCRL3, an Autoimmune Susceptibility Gene, (2009) (0)
Advance of Biotechnology and Analysis of Immune Disorders. (1997) (0)
In Vivo and the Regulatory Activity of CD 4-Positive 1 Expression β 3 Is Associated with the TGF-Transcription Factor Early Growth Response (2013) (0)
FRI0099 PREDICTIVE FACTORS FOR REMISSION ACHIEVEMENT BY TOCILIZUMAB MONOTHERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS AFTER INADEQUATE RESPONSE TO METHOTREXATE: A POST HOC ANALYSIS OF THE SURPRISE STUDY (2019) (0)
Contents Vol. 124, 2001 (2001) (0)
Cytokine-mediated regulation of toll-like receptor expression in eosinophils (2004) (0)
The First, Multicenter, Double-Blind, Randomized, Parallel-Group Study of Certolizumab Pegol in Early Rheumatoid Arthritis Demonstrates Inhibition of Joint Damage Progression. (2014) (0)
Mini Review JAK inhibition and modulation of T cell function (2013) (0)
Medical disease and molecular biology.4.Autoimmune disease. (1992) (0)
T Cells in Rheumatic Diseases (2000) (0)
Gene-based large scale LD-mapping of rheumatoid arthritis-associated genes (2006) (0)
Inflammationin a Mouse Model of Allergic Airway Antigen-Specific Systemic Immune Response Migration without Impairing the Down-Regulating APC Functions and Airway Eosinophilia and Hyperreactivity by In Vivo IL-10 Gene Delivery Suppresses (2005) (0)
SyndromeI-Associated and Idiopathic Sjögren's Human T Lymphotropic Virus Type in the Salivary Glands of Patients with Accumulation of Common T Cell Clonotypes (2000) (0)
Man-made nucleotide ligands: Selection from a random shape library. (1995) (0)
B-dependent pathway κ factor-in human bronchial epithelial cells via nuclear Diesel exhaust particles upregulate eotaxin gene (2016) (0)
Bronchial Epithelial Cells Activation-Regulated Chemokine by Human Chemokine Thymus-and Inducible Expression of a Th 2-Type CC (2000) (0)
P 815-Infiltrating Lymphocyte Isolated from a Clonally Expanded-Chain Genes βα Transfer of the TCR T Cells by Retroviral + Reconstitution of CD 8 (2003) (0)
Protein 2 in Systemic Autoimmune Diseases Low Density Lipoprotein Receptor-Related Anti-CD69 Autoantibodies Cross-React with (2000) (0)
Mouse to man (SY5-5) Chairpersons: Kazuhiko Yamamoto, Riitta Lahesmaa (2010) (0)
Immune Response to Self Nuclear Autoantigen Determines the Fate of Altered Expression Level of a Systemic (1999) (0)
757 Regulation of surface FcϵRI expession on human eosinophils by IL-4 and IgE (2000) (0)
Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells (2018) (0)
List of Lectures by Speakers Who Have Not Submitted Their Manuscripts (2013) (0)
[Retrospective thoughts on studies of allergy and collagen disease in the 20th Century and prospects for the 21st Century (discussion)]. (2002) (0)
Recent Advances in the Study of the Genetics of Rheumatic Diseases. (2010) (0)
THU0058 Intestinal Microbiota Plays A Critical Role in the Production of Antinuclear Antibodies in Lymphopenia-Induced Autoimmunity (2014) (0)
IL-33-induced activation of human basophils and eosinophils via ST2 (2010) (0)
Novel regulatory T cells controlling antibody production and systemic autoimmunity (2012) (0)
Pravastatin attenuates allergic airway inflammation by suppressing antigen-sensitization, IL-17 production, and antigen-presentation in the lung (2008) (0)
[Case report; A case of laryngeal sarcoidosis which was differentially diagnosed from tuberculosis]. (2013) (0)
Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population (2018) (0)
Splenic Macrophages Promotes Responses to Nucleosomes in NZB/W F1 Mice (2007) (0)
Internal medicine - prospect to twenty-first century. I. Prospects to the twenty-first century on each region of internal medicine. 8. Allergy and collagen disease. (2002) (0)
Protein 2 in Systemic Autoimmune Diseases Low Density Lipoprotein Receptor-Related Anti-CD 69 Autoantibodies Cross-React with Tomohiro (2000) (0)
Studies of T cell receptors in autoimmune diseases (1997) (0)
Symposium on Medical Diseases and Molecular Biology. 4. Molecular Analyses of Autoimmune Diseases. (1992) (0)
[Rheumatoid arthritis: progress in diagnosis and treatment. Topics: I. Pathogenesis; 1. Genetic factors of rheumatoid arthritis]. (2012) (0)
Is an autoimmune response exploding like the ‘Big Bang’ of the universe? (2000) (0)
[Studies on the genes related to rheumatoid arthritis and clinical application of the results]. (2007) (0)
TCR by Retroviral Transfer of the MHC-Restricted T Cell Immunity Mediated Functional Reconstitution of Class II (2000) (0)
[Genetic studies of connective tissue diseases]. (2010) (0)
Peripheral airway epithelium in chronic airway inflammatory diseases. Expression of cytokines/chemokines and responses to growth factors. A study with an ultrathin bronchofiberscope. (2000) (0)
THU0220 PEPTIDYLARGININE DEIMINASE 4 DEFICIENCY AMELIORATED A MURINE MODEL OF LUPUS BY REDUCING NEUTROPHIL MIGRATION TO THE KIDNEY (2019) (0)
Infusion of Infliximab in a Patient with Ankylosing Spondylitis Cardiopulmonary Arrest After Severe Anaphylactic Reaction to Second (2017) (0)
SP0056 MAPPING GENES TO IMMUNE CELLS (2019) (0)
How to Improve Medical Treatment of Collagen Disease and Rheumatoid Diseases (2009) (0)
Life science and medical science (2004) (0)
Lectins and glycoimmunology (WS-027) Chairpersons: Sho Yamasaki, Takako Hirata (2010) (0)
Subject Index Vol. 146, Suppl. 1, 2008 (2008) (0)
New Procedure of Medical Accident Investigation (2017) (0)
Dendritic cells: differentiation (WS-046) Chairpersons: Kayo Inaba, Laszlo Nagy (2010) (0)
Autotaxin may play a Critical Role between the Genetic Risk Factors and Pathogenesis of SLE in Plasmacytoid Dendritic Cells (2021) (0)
Faculty Opinions recommendation of CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. (2009) (0)
Erratum: Possible involvement of human T lymphotrophic virus type I in the pathogenesis of Sjogren's syndrome (Journal of Rheumatology (1997) 24 (53-54)) (1997) (0)
Eotaxin-2Th2 Cytokines, Th17 Cytokines, and of Inflammation Associated with Suppression Alendronate Attenuates Eosinophilic Airway (2013) (0)
Activation B κ That Regulates Nuclear Factor-Possible Role in the Signaling Pathway in Human Bronchial Epithelial Cells : Anti-Inflammatory Action of Erythromycin Molecular Mechanisms of (2004) (0)
Rheumatoid arthritis and other inflammatory joint diseases (human studies) (WS-036) Chairpersons: Tsutomu Takeuchi, Nobuyuki Miyasaka (2010) (0)
1. Progress on Diagnostic Tests for Rheumatoid Arthritis (2008) (0)
Collagen disease. New diagnosis and advances of therapy. Approach of collagen disease and advances of diagnosis. New approach of immunologic abnormalities. (1997) (0)
[Rheumatoid arthritis nd citrullinated antigens]. (2005) (0)
Abstract of a Lecture at the Workshop (2009) (0)
T cells and autoimmune diseases (2001) (0)
Faculty Opinions recommendation of The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. (2011) (0)
Title Predictive Factors for Reintubation following Noninvasive Ventilation in Patients with Respiratory Complications after Living Donor Liver Transplantation (2018) (0)
1. Genetic Factors of Rheumatoid Arthritis (2012) (0)
Accumulating T cell clones commonly detected in multiple joints in the patients with rheumatoid arthritis (1995) (0)
[Autoantigen BiP and autoimmune diseases]. (2012) (0)
Chemokine receptor expression profile of eosinophils in disordered conditions (2002) (0)
from the Inflamed Paw Gene Therapy of Arthritis with TCR Isolated (2013) (0)
[Progress in the studies on genes related to collagen and rheumatoid diseases]. (2010) (0)
cDNA Cloning and Expression of U1snRNP C Protein (1989) (0)
Splicing QTL analysis focusing on coding sequences reveals pathogenicity of disease susceptibility loci (2022) (0)
Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles. (2022) (0)

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