Kazutoshi Mori
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Molecular biologist
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Kazutoshi Moribiology Degrees
Biology
#584
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#1035
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Molecular Biology
#92
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#95
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Biology
Kazutoshi Mori's Degrees
- PhD Molecular Biology University of Tokyo
- Bachelors Agricultural Chemistry University of Tokyo
Why Is Kazutoshi Mori Influential?
(Suggest an Edit or Addition)According to Wikipedia, is a Japanese molecular biologist known for research on unfolded protein response. He is a professor of Biophysics at the Graduate School of Science, Kyoto University, and shared the 2014 Albert Lasker Basic Medical Research Award with Peter Walter for discoveries concerning the unfolded protein response — an intracellular quality control system that detects harmful misfolded proteins in the endoplasmic reticulum and signals the nucleus to carry out corrective measures.
Kazutoshi Mori's Published Works
Published Works
- XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor (2001) (3614)
- IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. (2002) (991)
- Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins (1998) (969)
- Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. (2007) (964)
- ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis-Acting Element Responsible for the Mammalian Unfolded Protein Response (2000) (933)
- Tripartite Management of Unfolded Proteins in the Endoplasmic Reticulum (2000) (913)
- AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. (1997) (856)
- Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins (2006) (773)
- Complementary Signaling Pathways Regulate the Unfolded Protein Response and Are Required for C. elegans Development (2001) (694)
- A time-dependent phase shift in the mammalian unfolded protein response. (2003) (691)
- Characterization of oligonucleotide transport into living cells. (1989) (681)
- Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb. (1995) (624)
- Distinct Roles of Thioredoxin in the Cytoplasm and in the Nucleus (1999) (614)
- XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. (2004) (559)
- Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. (2002) (522)
- Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis. (2003) (479)
- Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. (2004) (422)
- ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum. (2008) (420)
- pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response (2006) (412)
- cDNA cloning and regional distribution of a novel member of the opioid receptor family (1994) (405)
- Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic‐leucine zipper motif is required for the unfolded protein‐response pathway (1996) (382)
- Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation (2006) (370)
- Signalling pathways in the unfolded protein response: development from yeast to mammals. (2009) (353)
- Tumor Necrosis Factor α (TNFα) Induces the Unfolded Protein Response (UPR) in a Reactive Oxygen Species (ROS)-dependent Fashion, and the UPR Counteracts ROS Accumulation by TNFα* (2005) (339)
- XBP1 Is Essential for Survival under Hypoxic Conditions and Is Required for Tumor Growth (2004) (320)
- OCAM: A New Member of the Neural Cell Adhesion Molecule Family Related to Zone-to-Zone Projection of Olfactory and Vomeronasal Axons (1997) (311)
- Distribution of dendrites of mitral, displaced mitral, tufted, and granule cells in the rabbit olfactory bulb (1983) (300)
- ER stress activates the NLRP3 inflammasome via an UPR-independent pathway (2012) (294)
- XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. (2004) (281)
- Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress (2010) (268)
- Hepatitis C Virus Subgenomic Replicons Induce Endoplasmic Reticulum Stress Activating an Intracellular Signaling Pathway (2002) (267)
- Endoplasmic Reticulum Stress-Induced Formation of Transcription Factor Complex ERSF Including NF-Y (CBF) and Activating Transcription Factors 6α and 6β That Activates the Mammalian Unfolded Protein Response (2001) (264)
- Role of Disulfide Bridges Formed in the Luminal Domain of ATF6 in Sensing Endoplasmic Reticulum Stress (2006) (258)
- Nitric Oxide-induced Apoptosis in RAW 264.7 Macrophages Is Mediated by Endoplasmic Reticulum Stress Pathway Involving ATF6 and CHOP* (2002) (249)
- Hepatitis C Virus Suppresses the IRE1-XBP1 Pathway of the Unfolded Protein Response* (2004) (219)
- Distribution of the mRNA for a pituitary adenylate cyclase‐activating polypeptide receptor in the rat brain: An in situ hybridization study (1996) (212)
- Generation of Dopaminergic Neurons in the Adult Brain from Mesencephalic Precursor Cells Labeled with a nestin-GFP Transgene (2001) (209)
- RhoA Inhibits the Nerve Growth Factor-induced Rac1 Activation through Rho-associated Kinase-dependent Pathway* (2001) (205)
- A Serine Protease Inhibitor Prevents Endoplasmic Reticulum Stress-induced Cleavage but Not Transport of the Membrane-bound Transcription Factor ATF6* (2003) (205)
- Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow (2009) (203)
- Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha. (2005) (193)
- ATF6 modulates SREBP2‐mediated lipogenesis (2004) (186)
- Disturbed Activation of Endoplasmic Reticulum Stress Transducers by Familial Alzheimer's Disease-linked Presenilin-1 Mutations* (2001) (184)
- mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response. (2000) (182)
- A Thrombospondin-Dependent Pathway for a Protective ER Stress Response (2012) (175)
- Palindrome with Spacer of One Nucleotide Is Characteristic of thecis-Acting Unfolded Protein Response Element inSaccharomyces cerevisiae * (1998) (159)
- Small GTPase RhoG Is a Key Regulator for Neurite Outgrowth in PC12 Cells (2000) (151)
- Sli2 (Ypk1), a Homologue of Mammalian Protein Kinase SGK, Is a Downstream Kinase in the Sphingolipid-Mediated Signaling Pathway of Yeast (2000) (144)
- Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response (2009) (143)
- The trajectory of mitral cell axons in the rabbit olfactory cortex revealed by intracellular HRP injection (1984) (139)
- Immunohistochemical study of subclasses of olfactory nerve fibers and their projections to the olfactory bulb in the rabbit (1985) (138)
- Dysfunction of the Unfolded Protein Response during Global Brain Ischemia and Reperfusion (2003) (129)
- Functional Characterization of a Mammalian Sac1 and Mutants Exhibiting Substrate-specific Defects in Phosphoinositide Phosphatase Activity* (2000) (127)
- EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step (2014) (125)
- The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death* (2010) (123)
- Phosphorothioate and normal oligodeoxyribonucleotides with 5'-linked acridine: characterization and preliminary kinetics of cellular uptake. (1988) (120)
- Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. (2012) (115)
- Purification, Characterization, Molecular Cloning, and Subcellular Distribution of Neutral Ceramidase of Rat Kidney* (2001) (111)
- The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic β cells (2004) (110)
- Molecular Cloning of the Full-length cDNA Encoding Mouse Neutral Ceramidase (2000) (108)
- Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response (2001) (107)
- cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for κ‐subtype‐selective ligands (1993) (101)
- Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum. (2004) (100)
- Gα12 and Gα13 Interact with Ser/Thr Protein Phosphatase Type 5 and Stimulate Its Phosphatase Activity (2002) (100)
- An IFN-γ–stimulated ATF6–C/EBP-β–signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy (2012) (99)
- MM-1, a Novel c-Myc-associating Protein That Represses Transcriptional Activity of c-Myc* (1998) (97)
- pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. (2009) (96)
- Unconventional Splicing of HAC1/ERN4 mRNA Required for the Unfolded Protein Response (1998) (94)
- Rapostlin Is a Novel Effector of Rnd2 GTPase Inducing Neurite Branching* (2002) (91)
- ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease (2012) (91)
- Frame Switch Splicing and Regulated Intramembrane Proteolysis: Key Words to Understand the Unfolded Protein Response (2003) (89)
- cDNA Cloning and Chromosomal Localization of the Human Telencephalin and Its Distinctive Interaction with Lymphocyte Function-associated Antigen-1* (1997) (86)
- Primary structure of non-histone protein HMG1 revealed by the nucleotide sequence. (1988) (85)
- Socius Is a Novel Rnd GTPase-Interacting Protein Involved in Disassembly of Actin Stress Fibers (2002) (81)
- Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds. (2008) (80)
- Vascular Endothelial Cell Growth–Activated XBP1 Splicing in Endothelial Cells Is Crucial for Angiogenesis (2013) (73)
- Binding of T lymphocytes to hippocampal neurons through ICAM‐5 (telencephalin) and characterization of its interaction with the leukocyte integrin CD11a / CD18 (2000) (73)
- Nucleobindin 1 Controls the Unfolded Protein Response by Inhibiting ATF6 Activation* (2007) (72)
- Differential Responses to Nerve Growth Factor and Epidermal Growth Factor in Neurite Outgrowth of PC12 Cells Are Determined by Rac1 Activation Systems* (2001) (71)
- Deficiency of ATP2C1, a Golgi Ion Pump, Induces Secretory Pathway Defects in Endoplasmic Reticulum (ER)-associated Degradation and Sensitivity to ER Stress* (2005) (68)
- Immunological identification of the major disulfide-linked light component of silk fibroin. (1993) (68)
- XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells. (2006) (67)
- Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent proteins regulated by stage‐specific neural promoters (2001) (66)
- Electron microscopic and functional studies on platelets in gray platelet syndrome. (1984) (65)
- XBP1 (2004) (64)
- Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes. (1993) (62)
- Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury* (2015) (62)
- The Unfolded Protein Response Transducer ATF6 Represents a Novel Transmembrane-type Endoplasmic Reticulum-associated Degradation Substrate Requiring Both Mannose Trimming and SEL1L Protein* (2013) (62)
- ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis. (2019) (62)
- The unfolded protein response: the dawn of a new field (2015) (59)
- The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells. (2004) (58)
- OCAM reveals segregated mitral/tufted cell pathways in developing accessory olfactory bulb (1997) (58)
- Autoregulation of the HAC1 gene is required for sustained activation of the yeast unfolded protein response (2004) (58)
- The Fusion Oncoprotein PML-RARα Induces Endoplasmic Reticulum (ER)-associated Degradation of N-CoR and ER Stress* (2004) (57)
- The Sterol-sensing Endoplasmic Reticulum (ER) Membrane Protein TRC8 Hampers ER to Golgi Transport of Sterol Regulatory Element-binding Protein-2 (SREBP-2)/SREBP Cleavage-activated Protein and Reduces SREBP-2 Cleavage* (2009) (55)
- Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice (2015) (54)
- A role for the unfolded protein response in optimizing antibody secretion. (2004) (54)
- The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. (2012) (53)
- Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation. (2006) (53)
- Developmentally and spatially regulated expression of HNK-1 carbohydrate antigen on a novel phosphatidylinositol-anchored glycoprotein in rat brain (1991) (51)
- Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene (1999) (49)
- Inactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1-PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDX. (1999) (48)
- Transformation‐associated gene regulation by ATF6α during hepatocarcinogenesis (2006) (47)
- Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. (2002) (47)
- ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish (2013) (46)
- A Cellular UDP-glucose Deficiency Causes Overexpression of Glucose/Oxygen-regulated Proteins Independent of the Endoplasmic Reticulum Stress Elements* (2004) (46)
- Polarized distribution and cell type‐specific localization of telencephalin, an intercellular adhesion molecule (1998) (44)
- UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage–specific manner (2017) (42)
- The exercise-inducible bile acid receptor Tgr5 improves skeletal muscle function in mice (2018) (41)
- Luminal domain of ATF6 alone is sufficient for sensing endoplasmic reticulum stress and subsequent transport to the Golgi apparatus. (2011) (40)
- The cargo receptor ERGIC-53 is a target of the unfolded protein response. (2003) (39)
- Prostaglandin E2 Activates Ca2+ Channels in Bovine Adrenal Chromaffin Cells (1991) (38)
- Vertebrate unfolded protein response: mammalian signaling pathways are conserved in Medaka fish. (2011) (38)
- Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesis. (2006) (38)
- Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2. (2002) (36)
- XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling (2015) (35)
- Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway (2015) (35)
- Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4) (1998) (33)
- Subtilisin-like proprotein convertases, PACE4 and PC8, as well as furin, are endogenous proalbumin convertases in HepG2 cells. (1999) (33)
- Molecular and cellular properties of mammalian primary olfactory axons (1993) (33)
- Analysis of ATF6 activation in Site-2 protease-deficient Chinese hamster ovary cells. (2006) (33)
- The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation. (2013) (32)
- Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X (2018) (32)
- p31 Deficiency Influences Endoplasmic Reticulum Tubular Morphology and Cell Survival (2009) (31)
- Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells. (2010) (31)
- Activation of Hepatitis B Virus S Promoter by a Cell Type-Restricted IRE1-Dependent Pathway Induced by Endoplasmic Reticulum Stress (2005) (31)
- Molecular Diversity in Zebrafish NCAM Family: Three Members with Different VASE Usage and Distinct Localization (2001) (29)
- Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis (2016) (28)
- Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins. (2020) (28)
- A novel human PACE4 isoform, PACE4E is an active processing protease containing a hydrophobic cluster at the carboxy terminus. (1997) (28)
- Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish (2017) (28)
- Cellular immunoregulatory mechanisms in the central nervous system: Characterization of noninflammatory and inflammatory cerebrospinal fluid lymphocytes (1990) (25)
- Endoplasmic Reticulum Stress-induced mRNA Splicing Permits Synthesis of Transcription Factor Hac 1 p / Ern 4 p That Activates the Unfolded Protein Response (1997) (25)
- 5 Structure, Function, and Regulation of the Endoplasmic Reticulum Chaperone, BiP (1994) (24)
- Admission Values of D-dimer and C-reactive Protein (CRP) Predict the Long-term Outcomes in Acute Aortic Dissection. (2016) (23)
- SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line. (2011) (22)
- Schnurri-2 mutant mice are hypersensitive to stress and hyperactive (2006) (22)
- Human subtilisin-like proprotein convertase, PACE4 (SPC4) gene expression is highly regulated through E-box elements in HepG2 and GH4C1 cells. (1999) (22)
- The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells. (2009) (22)
- EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD (2020) (22)
- Identification of the G 13 ( cAMP-response-element-binding protein-related protein ) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response (21)
- Promoters of epithelialization induce expression of vascular endothelial growth factor in human gastric epithelial cells in primary culture (1997) (20)
- Congenital factor X deficiency in Japan. (1981) (20)
- A mitochondrial plasmid that promotes mitochondrial fusion inPhysarum polycephalum (1991) (19)
- Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy (2018) (19)
- Expression of the pS2 gene in human gastric cancer cells derived from poorly differentiated adenocarcinoma (1990) (18)
- Developmental changes in expression of small GTPase RhoG mRNA in the rat brain. (2002) (18)
- Synthesis of Network Polymers by Means of Addition Reactions of Multifunctional-Amine and Poly(ethylene glycol) Diglycidyl Ether or Diacrylate Compounds (2020) (18)
- Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in Hereditary GNE Inclusion-Body Myopathy (2015) (18)
- Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice. (2014) (17)
- Endotoxemia in liver diseases: detection by a quantitative assay using chromogenic substrate with perchloric acid pretreatment. (1985) (17)
- Developing germ cells in mouse testis express pheromone receptors (2001) (16)
- Induction of Bcl‐2 gene expression by intercellular information from hemopoietic supportive stromal cells to DA‐1 cells (1994) (16)
- Divest Yourself of a Preconceived Idea: Transcription Factor ATF6 Is Not a Soluble Protein! (2010) (15)
- Mammalian Unfolded Protein Response-Acting Element Responsible for the cis Presence of NF-Y ( CBF ) Directly to the ATF 6 Activated by Proteolysis Binds in the (2000) (15)
- SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation. (2017) (13)
- Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis (2019) (13)
- XBP 1 is Critical to Protect Cells from Endoplasmic Reticulum Stress : Evidence from Site-2 Protease-deficient Chinese Hamster Ovary Cells (2006) (12)
- Saccharomyces cerevisiae KAR2 (BiP) gene expression is induced by loss of cytosolic HSP70/Ssa1p through a heat shock element-mediated pathway. (1997) (12)
- Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice (2016) (10)
- A Procedure for In Situ Hybridization Combined with Retrograde Labeling of Neurons: Application to the Study of Cell Adhesion Molecule Expression in DiI-labeled Rat Pyramidal Neurons (1997) (9)
- Reinvestigation of disulfide-bonded oligomeric forms of the unfolded protein response transducer ATF6. (2019) (9)
- Murine Endothelial Cell Line Cells, F‐2: Interaction with Leukocytes and Cytokines Production (1993) (9)
- Gray platelet syndrome: relationship between morphological abnormality of the dense tubular system (DTS) and intracellular Ca++ mobilization in the platelet. (1989) (9)
- Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice (2010) (9)
- [A case of severe defibrination syndrome due to snake (Rhabdophis tigrinus) bite]. (1983) (9)
- Deletion of Atf6α enhances kainate-induced neuronal death in mice (2016) (9)
- Endoplasmic Reticulum-Associated Degradation Controls Virus Protein Homeostasis, Which Is Required for Flavivirus Propagation (2021) (8)
- A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models (2016) (8)
- Mu opioid receptor: expression and vagotomy-induced depletion of the mRNA in medullary preganglionic neurons. (1994) (8)
- Morphological changes of platelets during the process of platelet aggregation in gray platelet syndrome. (1986) (8)
- [Studies on blood coagulation in ulcerative colitis and Crohn's disease]. (1982) (7)
- Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes (2020) (7)
- [Cellular response to endoplasmic reticulum stress mediated by unfolded protein response pathway]. (1999) (7)
- Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD (2021) (6)
- [An autopsy case of AIDS with hemophilia A who died of DIC and gastrointestinal bleeding associated with gastric carcinoma (signet ring cell carcinoma)]. (1994) (6)
- Vps 4-A ( vacuolar protein sorting 4-A ) is a binding partner for a novel Rho family GTPase , Rnd 2 (5)
- [Unfolded protein response as a quality control mechanism of proteins]. (2004) (4)
- Platelet aggregation and plasma levels of beta-thromboglobulin in diabetes mellitus. (1981) (4)
- Effects of Leukocytic Pyrogen (Interleukin-1) on Local Cerebral Glucose Utilization in Rats with and without Premedication with Indomethacin or Dexamethasone (1988) (4)
- The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B (2021) (4)
- MULTIPLE OVERLAPPING CIRCUITS WITHIN OLFACTORY AND BASAL FOREBRAIN SYSTEMS (1981) (4)
- Processing of Odor Information During the Respiratory Cycle in Mice (2022) (3)
- Aberrant Synthesis and Secretion of a Human Epidermal Growth Factor-Like Immunoreactive Factor by Human Breast Cancer Cells (1988) (3)
- [Coagulation studies of Weber-Christian disease (author's transl)]. (1973) (3)
- [A case of acute myelogenous leukemia and brain tumor formation in complete remission (author's transl)]. (1977) (2)
- Vitronectin binds telencephalin and regulates dendritic spine morphogenesis (2011) (2)
- The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity (2021) (2)
- Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response using Medaka Fish. (2019) (2)
- The density and distribution of intramembrane particles in erythrocytes from persons with muscular dystrophies. (1982) (2)
- A Collection of Transgenic Medaka Strains for Efficient Site-Directed Transgenesis Mediated by phiC31 Integrase (2018) (2)
- Hemorrhagic diathesis in Weber-Christian disease. (1976) (2)
- Chemotherapy is superior to checkpoint inhibitors after radical surgery for urothelial carcinoma: A systematic review and network meta-analysis of oncologic and toxicity outcomes (2022) (2)
- Na+-K+-Activated Adenosine Triphosphatase Activity and Lipoperoxide Metabolites in Microvessels and Parenchymas of the Ischemic Brain (1985) (2)
- [A family of congenital combined deficiency of factor V and von Willebrand factor]. (1990) (1)
- High dose intact-immunoglobulin treatment for an HIV-infected asymptomatic carrier with hemophilia. (1990) (1)
- Trypsin Sensitivity Assay to Study the Folding Status of Proteins (2016) (1)
- A case of liver cirrhosis complicated with endotoxemia and disseminated intravascular coagulation: a case report. (1987) (1)
- Imaging findings and pathological correlations of subacute encephalopathy with neuronal intranuclear inclusion disease–Case report (2022) (1)
- INTRACELLULAR CA++ MOBILIZATION IN GRAY PLATELET SYNDROME. ELECTRONMICROSCOPIC STUDIES ON AEQUORIN LOADED PLATELETS (1987) (1)
- ATF6 modulates SREBP2‐mediated lipogenesis (2013) (1)
- Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models (2016) (1)
- [Mannose trimming mechanism in endoplasmic reticulum-associated degradation of glycoproteins]. (2016) (1)
- [Intracellular traffic of membrane-bound transcription factors]. (2003) (1)
- Evolutionary Aspects of the Unfolded Protein Response. (2022) (1)
- [Clinical and coagulation studies in 3 cases of congenital factor X deficiency and review of reported cases in Japan (author's transl)]. (1980) (1)
- [Platelet function and intracellular Ca2+ mobilization, especially with regard to morphological abnormalities]. (1989) (0)
- Visualization of functional neural pathways using WGA transgene-2: Olfactory pathway (1998) (0)
- Manabu Negishi and (2001) (0)
- Fibroblast growth factor receptor: A systematic review and meta-analysis of prognostic value and therapeutic options in patients with urothelial bladder carcinoma (2021) (0)
- Purified EDEM 3 or EDEM 1 Alone Produces 2 Determinant Oligosaccharide Structures from M 8 B 3 in Mammalian Glycoprotein ERAD 4 5 (0)
- Cloning and characterization of mitochondrial DNA from the Japanesse oyster, Crassostrea gigas (1989) (0)
- Supplementary material from "Sex pheromone of a coccoid insect with sexual and asexual lineages: fate of an ancestrally essential sexual signal in parthenogenetic females" (2017) (0)
- Dietary supplement of mushrooms promotes SCFA production and moderately associates with IgA production: A pilot clinical study (2023) (0)
- Discrepancy between clinical and nephroureterectomy tumors stage as well as grade in upper tract urothelial carcinoma (2021) (0)
- XBP1(S) and the mechanism of phospholipid biosynthesis (2006) (0)
- Meeting details (2005) (0)
- P-95 Bevacizumab, irinotecan and biweekly trifluridine/tipiracil for pretreated metastatic colorectal cancer: MODURATE, a phase Ib study (2022) (0)
- Impact of performance status on survival outcomes in prostate cancer patients treated with systemic therapy: A systematic review and meta-analysis of randomized controlled trials (2023) (0)
- [Analysis of the unfolded protein response: an intracellular signaling pathway from the endoplasmic reticulum to the nucleus]. (1998) (0)
- Demystifying the elusive claustrum and how it orchestrates slow-wave activity in the brain (2021) (0)
- The efficacy and safety of relugolix compared to degarelix in advanced prostate cancer patients: A network meta-analysis of randomized trials (2021) (0)
- Adverse events of different chemotherapy regimens in the first-line treatment of patients with advanced or metastatic urothelial cancer: A systematic review and network meta-analysis of randomized controlled trials (2021) (0)
- Synchronized top-down inputs from the olfactory cortex participate in the cell death of adult-born neurons in the olfactory bulb (2011) (0)
- Neurodegenerative mutant of ER membrane protein Seipin causes pathological ER stress. (2017) (0)
- MP32-16 FUNCTIONAL OUTCOMES IN FEMALE PATIENTS AFTER TRADITIONAL, ORGAN- AND NERVE-SPARING RADICAL CYSTECTOMY AND URINARY DIVERSION FOR BLADDER CANCER: A SYSTEMATIC REVIEW AND POOLED ANALYSES (2023) (0)
- Impact of gender on the efficacy of immune checkpoint inhibitors for urological cancers: A systematic review and meta-analysis (2023) (0)
- Olfactory bulb preferentially incorporates eliminated subset of newborn granule cells (2010) (0)
- AN INTEGRIN DOES NOT INVOLVE IN APOPTOTIC CELL DEATH IN HEMOCYTES OF CRASSOSTREA GIGAS INDUCED BY FIBRONECTIN PEPTIDES(Cell Biology and Morphology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan) (2001) (0)
- Electroantennographic responses and field attraction of an emerging invader, the red-necked longicorn beetle Aromia bungii (Coleoptera: Cerambycidae), to the chiral and racemic forms of its male-produced aggregation-sex pheromone (2018) (0)
- ChemInform Abstract: Synthetic Microbial Chemistry. Part 20. Synthesis of Trichostatin A, a Potent Differentiation Inducer of Friend Leukemic Cells, and Its Antipode. (1989) (0)
- [Mechanism of induction of BiP]. (1994) (0)
- Can ablation therapy be an alternative treatment to partial nephrectomy for clinical T1b renal tumors?: A systematic review and meta-analysis (2022) (0)
- Identification of neuromedin U precursor-related peptide and its possible role in the regulation of prolactin release (2017) (0)
- Author response: Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD (2021) (0)
- Author response: The neuropeptide tachykinin is essential for pheromone detection in a gustatory neural circuit (2015) (0)
- [Induction of stress proteins in the endoplasmic reticulum of Saccharomyces cerevisiae]. (1994) (0)
- First-line immunotherapy-based combinations for metastatic renal cell carcinoma: Systematic review and network meta-analysis (2022) (0)
- [Bleeding tendency in multiple myeloma--with special reference to platelet dysfunction (author's transl)]. (1979) (0)
- [Marked improvement in Evans' syndrome with pulse therapy of methylprednisolone]. (1986) (0)
- SUCCESSFUL PRESERVATION OF BLADDER CAPACITY IN A CASE OF INFLAMMATORY MYOFIBROBLASTIC TUMOR OF THE BLADDER MANAGED WITH LAPAROENDOSCOPIC SINGLE-SITE PARTIAL CYSTECTOMY (2020) (0)
- and exchanges during the editing process, as well as to Prof. Jean-Marie Lehn for agreeing to write a foreword to this book. As all the chapters were peer (2012) (0)
- Author response: Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes (2020) (0)
- The unfolded protein response (2012) (0)
- PD09-04 PREDICTION OF 90-DAY MORTALITY AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER IN LARGE-SCALE MULTICENTER COLLABORATION STUDY (2022) (0)
- Examination of day-surgery minimally invasive treatment for the otolaryngological region.Endermic solidified silicon cordoinjection for unilateral cordoparalysis. (1995) (0)
- Suppression of leukotriene B4 production is involved in the anti-pruritic action of Grifola frondosa in pollen allergy-induced ocular itching in mice (2021) (0)
- [Gray platelet syndrome--platelet function abnormality and alpha granule deficiency]. (1987) (0)
- Reduction of ligand-binding affinity of platelet thromboxane A2 receptor by halothane (1992) (0)
- Visualization of functional neural pathways using WGA transgene-3: Adenoviral vector system (1998) (0)
- Dendritic filopodia formation is mediated by the interaction between telencephalin and ERM proteins (2007) (0)
- Neural Circuitry for Stress Information of Environmental and Internal Odor Worlds (2022) (0)
- Oncological and safety profiles in patients undergoing simultaneous transurethral resection of bladder tumor and prostate: Results from a large multicenter international collaboration (2022) (0)
- Lasker Award Winner Kazutoshi Mori (2014) (0)
- The unfolded protein response : the dawn of a new fi eld (2015) (0)
- [Pulse methylprednisolone therapy in children with idiopathic thrombocytopenic purpura]. (1988) (0)
- 86 : IFN-γ, ER-stress, autophagy and antimicrobial defense: A novel ATF6/C/EBP-β centric signaling pathway (2013) (0)
- Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice (2023) (0)
- Perioperative and oncological outcomes of simultaneous transurethral resection of bladder tumour and prostate: Systematic review and meta-analysis (2023) (0)
- ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions. (2023) (0)
- A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b (2022) (0)
- Analysis of physiological function of IRE1 pathway redundant with PERK or ATF6 pathway (2019) (0)
- Non-glycosylated Seipin to Cause a Motor Neuron Disease Induces ER stress and Apoptosis by Inactivating the ER Calcium Pump SERCA2b (2021) (0)
- [Relationship between coagulation studies and histological findings in liver diseases (author's transl)]. (1975) (0)
- VEGF-Activated XBP1 Splicing in Endothelial Cells is Crucial for Angiogenesis (2013) (0)
- Dissection of the molecular mechanism of N-glycan dependent/independent endoplasmic reticulum-associated degradation pathways (2019) (0)
- Functional development of olfactory tubercle domains during weaning period in mice (2018) (0)
- The claustrum coordinates cortical slow-wave activity (2020) (0)
- The antipsychotic olanzapine targets proinsulin for endoplasmic reticulum-associated degradation in a pancreatic beta cell line (2017) (0)
- Author response: EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD (2020) (0)
- Placebo and nocebo response in the medical treatment of adults with nocturia: A systematic review and meta-analysis (2022) (0)
- A phase II study of nedaplatin and nab-paclitaxel for patients with previously untreated advanced squamous cell lung cancer (KRSG1302). (2018) (0)
- [Submucosal hemorrhages of the jejunum in a patient with hemophilia B]. (1985) (0)
- Impact of response to preoperative chemotherapy on the outcome of pulmonary metastasectomy for colorectal cancer: Results of a retrospective multicenter study. (2018) (0)
- A NEW DISORDER CHARACTERIZED BY FACTOR V DEFICIENCY AND MOLECULAR ABNORMALITY OF VON willEBRAND FACTOR ANTIGEN (1987) (0)
- Involvement of NF-κB in Ca2+ reperfusion-induced delayed apoptosis of cultured rat astrocytes (2000) (0)
- EPA-1718 - Neuropathological Alterations in FTD Cases with C9ORF72 Mutation - New Insights (2014) (0)
- Efficacy of systemic treatment in prostate cancer patients with visceral metastasis: A systematic review, meta-analysis, and network meta-analysis (2023) (0)
- A Study on the Development of Analytical Method for Trimethyl (octadecyl) Ammonium and it’s Salts in Sediment by LC-MS/MS, and the Change of its Concentrations Over the Years (2023) (0)
- Survival analysis of patients with T1LG bladder cancer treated with BCG immunotherapy (2023) (0)
- Radical prostatectomy versus high-dose-rate brachytherapy and hypo-fractionated external beam radiation combined with long-term androgen deprivation for high-risk prostate cancer (2022) (0)
- Diterpenoid Total Synthesis. Part 27. Synthesis and Structure Revision of Bifurcarenone, a Unique Monocyclic Diterpene in Combination with a Hydroquinone C7 Unit as an Inhibitor of Mitotic Cell Division. (1989) (0)
- 5th Japanese Association of Hepato‐Biliary‐Pancreatic Surgery (1993) (0)
- II. Dynamics of Function and Regulation of the Endoplasmic Reticulum. (2020) (0)
- Pembrolizumab outperforms tyrosine kinase inhibitors in the adjuvant therapy of patients with high-risk renal cell carcinoma: A systematic review and network meta-analysis (2022) (0)
- Nationwide Laboratory Surveillance of Progressive Multifocal Leukoencephalopathy in Japan: Fiscal Years 2011–2020 (2023) (0)
- [Alloalbuminemia and analbuminemia]. (1998) (0)
- The endoplasmic reticulum stress sensor, ATF6α, protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced dopaminergic neuronal death in a p38 Mitogen-Activated Protein Kinase dependent manner (2010) (0)
- Desmopressin is twice effective in females: A systematic review and meta-analysis on medical treatment of nocturia (2022) (0)
- The role of cytoreductive nephrectomy in the era of immune-combination therapies: A meta-analysis (2022) (0)
- [Sequential separation of factor VIII on aminohexyl (AH) sepharose 4 B and affinity chromatography]. (1982) (0)
- Chemokine/Interleukin Imbalance Aggravates the Pathology of Respiratory Syncytial Virus Infection (2022) (0)
- Analysis of ER stress-mediated Apoptosis in Medaka Fish (2017) (0)
- Oncofetal protein 5T4 regulates the dendrite arborization of olfactory bulb interneurons in an odor-evoked activity-dependent process (2011) (0)
- Derlin2/3 and Herp1/2 are required for endoplasmic reticulum-associated degradation of SEL1L-dependent substrates. (2015) (0)
- CLONING OF AN INTEGRIN β SUBUNIT FROM HEMOCYTES OF THE PACIFIC OYSTER, Crassastrea gigas(Cell Biology and Morphology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan) (2001) (0)
- Efficacy of Combination Therapy with Prednisolone and Calcineurin Inhibitor in Patients with Myositis-Associated Interstitial Lung Disease (2020) (0)
- The role of ER stress sensor ATF6α in the pathogenesis of Parkinson's disease (2009) (0)
- [Two cases of systemic lupus erythematosus accompanied by thrombocytopenic purpura (author's transl)]. (1979) (0)
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