Kazutoshi Takahashi

Kazutoshi Takahashi's AcademicInfluence.com Rankings

Kazutoshi Takahashi

Philosophy

#5540

World Rank

#8370

Historical Rank

Logic

#2802

World Rank

#3846

Historical Rank

philosophy Degrees

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Philosophy

Kazutoshi Takahashi's Degrees

PhD Biological Sciences Kyoto University
Doctorate Medicine Kyoto University

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Kazutoshi Takahashi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors (2006) (23456)
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors (2007) (16003)
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells (2003) (3297)
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts (2008) (2844)
Suppression of induced pluripotent stem cell generation by the p53–p21 pathway (2009) (1304)
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells (2008) (1069)
Induction of pluripotent stem cells from fibroblast cultures (2007) (1020)
Variation in the safety of induced pluripotent stem cell lines (2009) (875)
Hypoxia enhances the generation of induced pluripotent stem cells. (2009) (747)
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013) (661)
A decade of transcription factor-mediated reprogramming to pluripotency (2016) (598)
Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells (2012) (504)
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (2011) (489)
Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. (2015) (366)
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells (2003) (360)
Induced Pluripotent Stem Cells (2011) (343)
Generation of retinal cells from mouse and human induced pluripotent stem cells (2009) (322)
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells (2010) (298)
Fbx15 Is a Novel Target of Oct3/4 but Is Dispensable for Embryonic Stem Cell Self-Renewal and Mouse Development (2003) (281)
Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells (2013) (272)
Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy (2009) (248)
Generation of mouse-induced pluripotent stem cells with plasmid vectors (2010) (241)
Induced pluripotent stem cells in medicine and biology (2013) (241)
The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. (2014) (202)
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential (2014) (200)
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells (2013) (195)
[Induction of pluripotent stem cells from mouse fibroblast cultures]. (2006) (167)
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development. (2019) (162)
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease (2011) (161)
Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells (2009) (154)
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts (2009) (141)
Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A (2011) (135)
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts (2013) (118)
Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells—Brief Report (2009) (118)
Cell Therapy Using Human Induced Pluripotent Stem Cell‐Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice (2015) (118)
Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm (2014) (116)
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. (2012) (112)
Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells (2009) (106)
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway* (2005) (101)
Present and future challenges of induced pluripotent stem cells (2015) (100)
Human Induced Pluripotent Stem Cells on Autologous Feeders (2009) (99)
A developmental framework for induced pluripotency (2015) (95)
Induction of pluripotency by defined factors (2011) (95)
Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes (2014) (83)
Generation and characterization of human induced pluripotent stem cells. (2009) (67)
Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. (2012) (64)
Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells (2016) (58)
Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2). (2005) (55)
Cellular reprogramming – lowering gravity on Waddington's epigenetic landscape (2012) (54)
Orderly hematopoietic development of induced pluripotent stem cells via Flk‐1+ hemoangiogenic progenitors (2009) (50)
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells (2018) (50)
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. (2010) (49)
Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells (2013) (44)
Reversal of Hypopigmentation in Phenylketonuria Mice by Adenovirus-Mediated Gene Transfer (1999) (40)
Identification of genes involved in tumor-like properties of embryonic stem cells. (2006) (35)
Mutation and polymorphic marker analyses of 65K- and 67K-glutamate decarboxylase genes in two families with pyridoxine-dependent epilepsy (1998) (28)
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models (2016) (28)
Impaired adipogenic capacity in induced pluripotent stem cells from lipodystrophic patients with BSCL2 mutations. (2016) (27)
The homeobox gene DLX4 promotes generation of human induced pluripotent stem cells (2014) (24)
Direct reprogramming 101 (2010) (22)
Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells (2021) (21)
Preparation of 1,8-di-O-alkylaloe-emodins and 15-amino-, 15-thiocyano-, and 15-selenocyanochrysophanol derivatives from aloe-emodin and studying their cytotoxic effects. (2008) (20)
Crystal structure of Bifidobacterium Longum phosphoketolase; key enzyme for glucose metabolism in Bifidobacterium (2010) (20)
ECAT11/L1td1 Is Enriched in ESCs and Rapidly Activated During iPSCGeneration, but It Is Dispensable for the Maintenance and Induction of Pluripotency (2011) (19)
Relation between tRNase activity and the structure of colicin D according to X-ray crystallography. (2004) (19)
MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. (2018) (18)
ERas is Expressed in Primate Embryonic Stem Cells but not Related to Tumorigenesis (2009) (18)
Interaction Analysis of FABP4 Inhibitors by X-ray Crystallography and Fragment Molecular Orbital Analysis. (2016) (18)
Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells. (2020) (16)
Novel phenylketonuria mutation detected by analysis of ectopically transcribed phenylalanine hydroxylase mRNA from lymphoblast (1992) (15)
Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes (2015) (14)
Cellular reprogramming. (2014) (12)
Chromatographic analysis of site-specific antibody-drug conjugates produced by AJICAP first-generation technology using a recombinant FcγIIIa receptor-ligand affinity column. (2021) (12)
One-step construction of ferritin encapsulation drugs for cancer chemotherapy. (2021) (11)
Self-Renewal and Mouse Development Dispensable for Embryonic Stem Cell Fbx 15 Is a Novel Target of Oct 3 / 4 but Is (2003) (10)
Crystal Structure of Bifidobacterium Longum Phosphoketolase (2010) (10)
The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency (2020) (9)
Protein engineering for improving the thermostability of tryptophan oxidase and insights from structural analysis (2018) (9)
Anti-A b Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer ’ s Disease (2011) (7)
Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates. (2021) (7)
Lipoate-acid Ligase A modification of Native Antibody: Synthesis and Conjugation Site Analysis. (2021) (6)
Response to Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells” (2013) (6)
Substrate recognition mechanism of tRNA-targeting ribonuclease, colicin D, and an insight into tRNA cleavage-mediated translation impairment (2020) (6)
Transfer-messenger RNA and SmpB mediate bacteriostasis in Escherichia coli cells against tRNA cleavage. (2015) (6)
Generation of high quality iPS cells (2007) (5)
Mitochondrial tRNA cleavage by tRNA-targeting ribonuclease causes mitochondrial dysfunction observed in mitochondrial disease. (2014) (5)
Faculty of 1000 evaluation for CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency. (2018) (4)
" Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells " ( 2007 ) , by Junying Yu (2017) (4)
Faculty Opinions recommendation of Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency. (2019) (3)
Faculty Opinions recommendation of CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. (2018) (3)
Improved Sendai viral system for reprogramming to naive pluripotency (2022) (3)
Evidence for DNA Cleavage Caused Directly by a transfer RNA-Targeting Toxin (2013) (2)
Purification, crystallization and preliminary X-ray analysis of the catalytic domain of the Escherichia coli tRNase colicin D. (2006) (2)
Naohiro Egawa Cells Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem (2012) (2)
Single-chain tandem macrocyclic peptides as a scaffold for growth factor and cytokine mimetics (2022) (2)
Development of a rapid and simple glycine analysis method using a stable glycine oxidase mutant. (2019) (2)
Generation of Retinal Progenitor Cells From Human Induced Pluripotent Stem Cells (2009) (2)
Generation of disease-specific induced pluripotent stem cells from Alzheimer's disease patients (2010) (2)
Faculty Opinions recommendation of Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity. (2016) (1)
The Past, Present and Future of Induced Pluripotent Stem Cells (2011) (1)
Exocyst complex component 2 is a potential host factor for SARS-CoV-2 infection (2022) (1)
Generation of disease-specific induced pluripotent stem cells from sporadic Parkinson's disease patients (2011) (1)
Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo. (2009) (1)
Faculty Opinions recommendation of An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. (2018) (1)
Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells (2022) (1)
Title ECAT 11 / L 1 td 1 is enriched in ESCs and rapidly activated during iPSC generation , but it is dispensable for the maintenance and induction of pluripotency (2017) (1)
"Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (2007), by Junying Yu et al. [1] (2018) (0)
Crystal Structure of FABP4 in complex with 3-(5-cyclopropyl-2,3-diphenyl-1H-indol-1-yl)propanoic acid (2016) (0)
A Cell-ebration of Induced Pluripotency (2016) (0)
Differentiation of induced pluripotent stem cells from ALS patients generates motor neurons (2010) (0)
Faculty Opinions recommendation of Generation of human oogonia from induced pluripotent stem cells in vitro. (2018) (0)
Faculty of 1000 evaluation for Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency. (2018) (0)
Faculty Opinions recommendation of Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts. (2019) (0)
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007 (2018) (0)
Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts " ( 2007 ) , by Masato (2019) (0)
model for dissecting somatic mosaicism and drug discovery Induced pluripotent stem cells from CINCA syndrome patients as a (2013) (0)
Faculty Opinions recommendation of Discovery and validation of human genomic safe harbor sites for gene and cell therapies. (2022) (0)
A Cell-ebration of Induced Pluripotency. (2016) (0)
"Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins" (2009), by Hongyan Zhou et al (2018) (0)
" Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins " ( 2009 ) , by Hongyan Zhou (2018) (0)
Embryonic stem cells express a transforming oncogene (2005) (0)
"Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts" (2007), by Masato Nakagawa et al (2017) (0)
The iPS Breakthrough Paper (2014) (0)
Faculty Opinions recommendation of Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation. (2020) (0)
Post-transcriptionally regulated genes are essential for pluripotent stem cell survival (2021) (0)
Crystal Structure of FABP4 in complex with 3-[5-cyclopropyl-3-(3-methoxypyridin-4-yl)-2-phenyl-1H-indol-1-yl] propanoic acid (2016) (0)
" Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts " ( 2007 ) (2018) (0)
Faculty Opinions recommendation of yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs. (2019) (0)
Faculty Opinions recommendation of Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. (2021) (0)
Aoi Stomach Cells Generation of Pluripotent Stem Cells from Adult Mouse Liver and (2012) (0)
Mouse Molecular Genetics Symposium : Upstream and downstream regulators of Nanog and ERas, two important molecules in ES cell biology (2004) (0)
Faculty Opinions recommendation of Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4. (2019) (0)
Title Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice (2019) (0)
"Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (2007), by Junying Yu et al. (2022) (0)
Faculty of 1000 evaluation for Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. (2018) (0)
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007 [ 1 ] (2019) (0)
Faculty Opinions recommendation of Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. (2020) (0)
Faculty Opinions recommendation of Xist nucleates local protein gradients to propagate silencing across the X chromosome. (2021) (0)
Faculty Opinions recommendation of Human naive epiblast cells possess unrestricted lineage potential. (2021) (0)
Faculty Opinions recommendation of Mapping Gene Circuits Essential for Germ Layer Differentiation via Loss-of-Function Screens in Haploid Human Embryonic Stem Cells. (2020) (0)
Derivation of Human Induced Pluripotent Stem Cells on Autologous Feeders (2011) (0)
Faculty Opinions recommendation of A widespread alternate form of cap-dependent mRNA translation initiation. (2018) (0)
Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid (2016) (0)
Cooperative Study Combining X-ray Crystal Structure Analysis and FMO Calculation: Interaction Analysis of FABP4 Inhibitors (2021) (0)
Establishment of iPS cells from amyotrophic lateral sclerosis model mice and motor neuronal differentiation (2011) (0)
[Simple test for the evaluation of the safety of human induced pluripotent stem cells]. (2010) (0)
Neurodegenerative disease-specific induced pluripotent Stem cells research (2009) (0)
"Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (2007), by Junying Yu et al. [1] (2022) (0)
Methode de reprogrammation nucleaire (2008) (0)
Generation of disease-specific induced pluripotent stem cells from hereditary Parkinson’s disease (2010) (0)
Faculty Opinions recommendation of Distinct molecular trajectories converge to induce naive pluripotency. (2019) (0)
In-vivo Imaging of Neuronal Differentiation and Function of Intracranially Implanted Induced Pluripotent Stem Cells (iPSCs) Using A Designer Receptor Exclusively Activated by A Designer Drug (DREADD) (2014) (0)
Generation of Retinal Progenitor Cells From Induced Pluripotent Stem (iPS) Cells (2008) (0)
Faculty Opinions recommendation of Metabolic Control over mTOR-Dependent Diapause-like State. (2020) (0)
A stress-reduced passaging technique improves the viability of human pluripotent cells (2021) (0)
Induction of astrocyte differentiation from human induced pluripotent stem cells carrying mutant SOD1 (2011) (0)
Ribonuclease from Escherichia coli complexed with its inhibitor protein (2005) (0)
Establishment of iPS cells from amyotrophic lateral sclerosis model mice (2010) (0)
Crystal Structure of FABP4 in complex with 3-(2-phenyl-1H-indol-1-yl)propanoic acid (2016) (0)
Faculty Opinions recommendation of Mailing viable mouse freeze-dried spermatozoa on postcards. (2021) (0)
18 The Past , Present and Future of Induced Pluripotent Stem Cells (2012) (0)
Faculty Opinions recommendation of Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs. (2020) (0)

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What Schools Are Affiliated With Kazutoshi Takahashi?

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