Keith P. Klugman
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(Suggest an Edit or Addition)Keith P. Klugman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. (2003) (1041)
- Rapid Pneumococcal Evolution in Response to Clinical Interventions (2011) (865)
- Antimicrobial resistance in developing countries. Part I: recent trends and current status. (2005) (842)
- Pneumococcal resistance to antibiotics (1990) (834)
- Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis (2011) (815)
- Access to effective antimicrobials: a worldwide challenge (2016) (800)
- Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. (2000) (644)
- Epidemiological differences among pneumococcal serotypes. (2005) (602)
- Outcome of Cephalosporin Treatment for Serious Infections Due to Apparently Susceptible Organisms Producing Extended-Spectrum β-Lactamases: Implications for the Clinical Microbiology Laboratory (2001) (596)
- Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. (2004) (581)
- Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. (1999) (549)
- A role for Streptococcus pneumoniae in virus-associated pneumonia (2004) (540)
- Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns (2002) (534)
- Nomenclature of Major Antimicrobial-Resistant Clones of Streptococcus pneumoniae Defined by the Pneumococcal Molecular Epidemiology Network (2001) (531)
- Pneumococcal Capsules and Their Types: Past, Present, and Future (2015) (493)
- An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. (2003) (460)
- Influenza vaccination of pregnant women and protection of their infants. (2014) (443)
- Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia. (2000) (432)
- Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia. (2004) (432)
- International Prospective Study of Klebsiella pneumoniae Bacteremia: Implications of Extended-Spectrum -Lactamase Production in Nosocomial Infections (2004) (415)
- Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants. (2003) (357)
- Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group. (2013) (352)
- Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. (2010) (332)
- Global epidemiology of invasive meningococcal disease (2013) (324)
- Antimicrobial resistance in developing countries. Part II: strategies for containment. (2005) (306)
- Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies. (2007) (302)
- Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence. (2002) (296)
- Virulence Characteristics of Klebsiella and Clinical Manifestations of K. pneumoniae Bloodstream Infections (2007) (288)
- PROTECTIVE ACTIVITY OF VI CAPSULAR POLYSACCHARIDE VACCINE AGAINST TYPHOID FEVER (1987) (283)
- Impact of Pneumococcal Conjugate Vaccination of Infants on Pneumonia and Influenza Hospitalization and Mortality in All Age Groups in the United States (2011) (240)
- Bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with acute bacterial meningitis (1995) (235)
- Maternal Influenza Immunization and Reduced Likelihood of Prematurity and Small for Gestational Age Births: A Retrospective Cohort Study (2011) (234)
- Impact of conjugate pneumococcal vaccines on antibiotic resistance. (2008) (233)
- Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy. (2001) (228)
- Increased Antimicrobial Resistance Among Nonvaccine Serotypes of Streptococcus pneumoniae in the Pediatric Population After the Introduction of 7-Valent Pneumococcal Vaccine in the United States (2007) (224)
- Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization. (1996) (220)
- The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and -uninfected children. (2005) (214)
- Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis. (2009) (201)
- Failure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitis (1992) (199)
- Antimicrobial resistance in Streptococcus pneumoniae: a South African perspective. (1992) (182)
- Effect of 13-valent pneumococcal conjugate vaccine on admissions to hospital 2 years after its introduction in the USA: a time series analysis. (2014) (178)
- Acquisition, carriage, and transmission of pneumococci with decreased antibiotic susceptibility in young children attending a day care facility in southern Israel. (1998) (175)
- Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines. (2002) (174)
- Effects of vaccination on invasive pneumococcal disease in South Africa. (2014) (173)
- Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance. (2009) (166)
- Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children (2000) (164)
- High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia. (2014) (162)
- Pneumococcal Capsular Switching: A Historical Perspective (2012) (159)
- Prevalence of maternal colonisation with group B streptococcus: a systematic review and meta-analysis. (2016) (156)
- Antibiotic-resistant pneumococcal disease in South African children. (1992) (155)
- Novel Mechanism of Resistance to Oxazolidinones, Macrolides, and Chloramphenicol in Ribosomal Protein L4 of the Pneumococcus (2005) (153)
- Randomized comparison of meropenem with cefotaxime for treatment of bacterial meningitis. Meropenem Meningitis Study Group (1995) (150)
- Fitness Costs of Fluoroquinolone Resistance in Streptococcus pneumoniae (2006) (148)
- Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003. (2011) (148)
- Influence of bacterial interactions on pneumococcal colonization of the nasopharynx. (2013) (145)
- Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study. (2007) (145)
- Pneumococcal pneumonia and influenza: a deadly combination. (2009) (142)
- Efficacy of pneumococcal conjugate vaccines and their effect on carriage and antimicrobial resistance. (2001) (139)
- The impact of HIV on Streptococcus pneumoniae bacteraemia in a South African population (1998) (136)
- The relationship between pneumococcal serotypes and antibiotic resistance. (2012) (134)
- Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine. (2007) (134)
- The LuxS-Dependent Quorum-Sensing System Regulates Early Biofilm Formation by Streptococcus pneumoniae Strain D39 (2011) (133)
- Drug resistance patterns and serogroups or serotypes of pneumococcal isolates from cerebrospinal fluid or blood, 1979-1986. (1988) (132)
- Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae--and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization--in HIV-Infected and HIV-uninfected children. (2007) (130)
- Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae (1997) (127)
- A framework for global surveillance of antibiotic resistance. (2011) (127)
- Association between Respiratory Syncytial Virus Activity and Pneumococcal Disease in Infants: A Time Series Analysis of US Hospitalization Data (2015) (126)
- Alterations in PBP 1A Essential for High-Level Penicillin Resistance in Streptococcus pneumoniae (1998) (126)
- Hidden Epidemic of Macrolide-resistant Pneumococci (2005) (123)
- Emergence and Spread of Streptococcus pneumoniae with erm(B) and mef(A) Resistance (2005) (122)
- Levofloxacin-Resistant Invasive Streptococcus pneumoniae in the United States: Evidence for Clonal Spread and the Impact of Conjugate Pneumococcal Vaccine (2004) (117)
- Development of the Respiratory Index of Severity in Children (RISC) Score among Young Children with Respiratory Infections in South Africa (2012) (115)
- Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes. (1997) (115)
- LACK OF UTILITY OF SEROTYPING MULTIPLE COLONIES FOR DETECTION OF SIMULTANEOUS NASOPHARYNGEAL CARRIAGE OF DIFFERENT PNEUMOCOCCAL SEROTYPES (2000) (113)
- Human Metapneumovirus–Associated Lower Respiratory Tract Infections among Hospitalized Human Immunodeficiency Virus Type 1 (HIV-1)–Infected and HIV-1–Uninfected African Infants (2003) (113)
- Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study (2019) (112)
- International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact (2019) (110)
- Impact of existing vaccines in reducing antibiotic resistance: Primary and secondary effects (2018) (109)
- Typhoid fever vaccines. (1999) (107)
- Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants. (2010) (107)
- Pneumococcal coinfection with human metapneumovirus. (2006) (105)
- Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa. (2008) (105)
- Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection (2002) (104)
- Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia. (2008) (103)
- HIV and pneumococcal disease (2007) (103)
- Quantitative and Qualitative Antibody Response to Pneumococcal Conjugate Vaccine Among African Human Immunodeficiency Virus-Infected and Uninfected Children (2005) (102)
- The successful clone: the vector of dissemination of resistance in Streptococcus pneumoniae. (2002) (99)
- Increased carriage of trimethoprim/sulfamethoxazole-resistant Streptococcus pneumoniae in Malawian children after treatment for malaria with sulfadoxine/pyrimethamine. (2000) (99)
- Guidelines for empiric antimicrobial prescribing in community-acquired pneumonia. (2004) (98)
- Emergence of Streptococcus pneumoniae with Very-High-Level Resistance to Penicillin (2004) (98)
- Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis. (2010) (97)
- Nasopharyngeal carriage and antimicrobial resistance in isolates of Streptococcus pneumoniae and Haemophilus influenzae type b in children under 5 years of age in Botswana. (1998) (97)
- Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial (2009) (97)
- Density Interactions Among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the Nasopharynx of Young Peruvian Children (2013) (96)
- Evidence for Soft Selective Sweeps in the Evolution of Pneumococcal Multidrug Resistance and Vaccine Escape (2014) (96)
- Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms (2013) (93)
- Increased risk for and mortality from invasive pneumococcal disease in HIV-exposed but uninfected infants aged <1 year in South Africa, 2009-2013. (2015) (92)
- Bacterial pathogens and death during the 1918 influenza pandemic. (2009) (92)
- Surveillance of resistance in bacteria causing community-acquired respiratory tract infections. (2002) (92)
- Role of Streptococcus pneumoniae in Hospitalization for Acute Community-acquired Pneumonia Associated With Culture-confirmed Mycobacterium tuberculosis in Children: A Pneumococcal Conjugate Vaccine Probe Study (2010) (90)
- The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies (2015) (90)
- Epidemiology of invasive pneumococcal disease among high-risk adults since the introduction of pneumococcal conjugate vaccine for children. (2013) (90)
- Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States. (2010) (90)
- Pneumococcal vaccination in developing countries (2006) (88)
- Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa (1993) (87)
- Pneumococcal vaccines: the impact of conjugate vaccine. (2008) (86)
- Alterations in MurM, a Cell Wall Muropeptide Branching Enzyme, Increase High-Level Penicillin and Cephalosporin Resistance in Streptococcus pneumoniae (2001) (85)
- The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis (2011) (85)
- The future of pneumococcal disease prevention. (2011) (84)
- Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice (2014) (84)
- Nasopharyngeal carriage of community-acquired, antibiotic-resistant Streptococcus pneumoniae in a Zambian paediatric population. (1997) (83)
- Quorum-Sensing Systems LuxS/Autoinducer 2 and Com Regulate Streptococcus pneumoniae Biofilms in a Bioreactor with Living Cultures of Human Respiratory Cells (2013) (83)
- Surveillance for Antimicrobial Drug Resistance in Under-Resourced Countries (2014) (80)
- A century of pneumococcal vaccination research in humans. (2012) (80)
- Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae (1995) (80)
- Increasing prevalence of penicillin-resistant pneumococcal infections in children in southern Israel: implications for future immunization policies. (1994) (78)
- Sequence of the structural gene (rmpM) for the class 4 outer membrane protein of Neisseria meningitidis, homology of the protein to gonococcal protein III and Escherichia coli OmpA, and construction of meningococcal strains that lack class 4 protein (1989) (78)
- Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci. (1986) (78)
- Carriage of penicillin resistant pneumococci. (1986) (77)
- Recommendations for treatment of childhood non-severe pneumonia (2009) (76)
- Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa (2010) (76)
- The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children? (2002) (75)
- Penetration of meropenem into the cerebrospinal fluid of patients with inflamed meninges. (1994) (75)
- Human Metapneumovirus Genetic Variability, South Africa (2005) (73)
- Analysis of Penicillin-Binding Protein Genes of Clinical Isolates of Streptococcus pneumoniae with Reduced Susceptibility to Amoxicillin (2002) (73)
- Serotype 19F Multiresistant Pneumococcal Clone Harboring Two Erythromycin Resistance Determinants [erm(B) and mef(A)] in South Africa (2001) (72)
- Bacteremic pneumococcal pneumonia in HIV-seropositive and HIV-seronegative adults. (1999) (71)
- Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia. (2002) (70)
- Lower respiratory tract infections associated with influenza A and B viruses in an area with a high prevalence of pediatric human immunodeficiency type 1 infection (2002) (70)
- Laboratory-based diagnosis of pneumococcal pneumonia: state of the art and unmet needs. (2011) (69)
- The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition (2014) (69)
- Increased activity of 16-membered lactone ring macrolides against erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae: characterization of South African isolates. (1998) (68)
- Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa (2002) (68)
- COVID-19 pneumonia and the appropriate use of antibiotics (2020) (68)
- Global practices of meningococcal vaccine use and impact on invasive disease (2014) (68)
- World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines. (2007) (67)
- Variable recombination dynamics during the emergence, transmission and ‘disarming’ of a multidrug-resistant pneumococcal clone (2014) (67)
- Introduction: historical perspective and development of amoxicillin/clavulanate. (2007) (67)
- Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care. (2009) (66)
- The Role of Influenza and Parainfluenza Infections in Nasopharyngeal Pneumococcal Acquisition Among Young Children (2014) (66)
- Conserved Mutations in the Pneumococcal Bacteriocin Transporter Gene, blpA, Result in a Complex Population Consisting of Producers and Cheaters (2011) (66)
- Childhood pneumonia in developing countries. (2013) (65)
- Increased prevalence of pediatric pneumococcal serotypes in elderly adults. (2005) (65)
- The role of influenza in the severity and transmission of respiratory bacterial disease. (2014) (63)
- Cost-effectiveness of pneumococcal conjugate vaccine: an update after 7 years of use in the United States. (2009) (63)
- Rapid Detection of Penicillin-Resistant Streptococcus pneumoniae in Cerebrospinal Fluid by a Seminested-PCR Strategy (1998) (62)
- Communicating trends in resistance using a drug resistance index (2011) (62)
- Identification of the tetracycline resistance gene, tet(O), in Streptococcus pneumoniae (1996) (62)
- Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin (2002) (61)
- Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children. (2005) (61)
- Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. (2007) (61)
- Consensus: management of infections in children caused by Streptococcus pneumoniae with decreased susceptibility to penicillin (1995) (59)
- In Vitro Evaluation of the Antimicrobial Activity of Ceftaroline against Cephalosporin-Resistant Isolates of Streptococcus pneumoniae (2008) (59)
- The remaining challenge of pneumonia: the leading killer of children. (2011) (59)
- Pneumococcal Vaccines and Flu Preparedness (2007) (59)
- Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study (2008) (59)
- Seasonality, Incidence, and Repeat Human Metapneumovirus Lower Respiratory Tract Infections in an Area With a High Prevalence of Human Immunodeficiency Virus Type-1 Infection (2007) (58)
- Efficacy of Maternal Influenza Vaccination Against All-Cause Lower Respiratory Tract Infection Hospitalizations in Young Infants: Results From a Randomized Controlled Trial (2017) (58)
- Temporal Changes in Pneumococcal Colonization in a Rural African Community With High HIV Prevalence Following Routine Infant Pneumococcal Immunization (2013) (56)
- Trends in antimicrobial resistance and serotype distribution of blood and cerebrospinal fluid isolates of Streptococcus pneumoniae in South Africa, 1991-1998. (2000) (55)
- Defining the Estimated Core Genome of Bacterial Populations Using a Bayesian Decision Model (2014) (54)
- Cerebrospinal fluid bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime (1997) (54)
- Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. (2010) (53)
- Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones. (2002) (53)
- Pneumococcal conjugate vaccines: proceedings from an interactive symposium at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy. (2003) (53)
- Bacteraemic pneumococcal pneumonia: impact of HIV on clinical presentation and outcome. (2007) (53)
- 25 – Pneumococcal conjugate vaccine and pneumococcal common protein vaccines (2013) (53)
- Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination. (2009) (53)
- Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008. (2013) (52)
- Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae. (2006) (52)
- Persistence of antibodies to the Salmonella typhi Vi capsular polysaccharide vaccine in South African school children ten years after immunization. (1999) (52)
- "Megaprimer" method of PCR-based mutagenesis: the concentration of megaprimer is a critical factor. (1997) (52)
- The clinical relevance of in-vitro resistance to penicillin, ampicillin, amoxycillin and alternative agents, for the treatment of community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. (1996) (51)
- Molecular Basis of Rifampin Resistance inStreptococcus pneumoniae (1999) (51)
- Aeromonas species isolated from medicinal leeches. (1999) (51)
- Persistent High Burden of Invasive Pneumococcal Disease in South African HIV-Infected Adults in the Era of an Antiretroviral Treatment Program (2011) (51)
- In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus (1996) (51)
- Five-year cohort study of hospitalization for respiratory syncytial virus associated lower respiratory tract infection in African children. (2006) (51)
- Gender as a risk factor for both antibiotic resistance and infection with pediatric serogroups/serotypes, in HIV-infected and -uninfected adults with pneumococcal bacteremia. (2004) (51)
- Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children (2003) (50)
- Streptococcus pneumoniae respiratory tract infections. (2001) (50)
- Antibiotic-resistant pneumococci in pediatric disease. (1995) (50)
- Impact of Haemophilus influenzae Type b Conjugate Vaccine in South Africa and Argentina (2004) (49)
- The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success (2012) (48)
- The role of fourth-generation cephalosporins in the treatment of infections caused by penicillin-resistant streptococci (1997) (48)
- Concentration-dependent killing of antibiotic-resistant pneumococci by the methoxyquinolone moxifloxacin. (1997) (48)
- Management of antibiotic-resistant pneumococcal infections. (1994) (47)
- Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine naïve mother-child dyads (2013) (47)
- The "Achilles heel" of global efforts to combat infectious diseases. (2006) (46)
- Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia (2014) (46)
- Effectiveness of 7-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in HIV-Infected and -Uninfected Children in South Africa: A Matched Case-Control Study (2014) (45)
- Emergence of drug resistance. Impact on bacterial meningitis. (1999) (45)
- Effectiveness of 7-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in HIV-Infected and -Uninfected Children in South Africa: A Matched Case-Control Study (2014) (45)
- New Gene Cassettes for Trimethoprim Resistance,dfr13, and Streptomycin-Spectinomycin Resistance,aadA4, Inserted on a Class 1 Integron (2000) (45)
- Invasive Pneumococcal Pneumonia and Respiratory Virus Co-infections (2012) (44)
- Clinical Epidemiology of Bocavirus, Rhinovirus, Two Polyomaviruses and Four Coronaviruses in HIV-Infected and HIV-Uninfected South African Children (2014) (44)
- Live attenuated influenza vaccine, but not pneumococcal conjugate vaccine, protects against increased density and duration of pneumococcal carriage after influenza infection in pneumococcal colonized mice. (2013) (44)
- Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009–2011 (2016) (44)
- Epidemiology of Group B Streptococcus in developing countries. (2013) (44)
- Mutations in Ribosomal Protein L16 Conferring Reduced Susceptibility to Evernimicin (SCH27899): Implications for Mechanism of Action (2000) (44)
- Impact of the Hajj on pneumococcal transmission. (2015) (43)
- Meningococcal Disease in South Africa, 1999–2002 (2007) (43)
- The role of clonality in the global spread of fluoroquinolone-resistant bacteria. (2003) (42)
- Identifying transmission routes of Streptococcus pneumoniae and sources of acquisitions in high transmission communities (2017) (42)
- Low prevalence of fluoroquinolone resistant strains and resistance precursor strains in Streptococcus pneumoniae from patients with community-acquired pneumonia despite high fluoroquinolone usage. (2011) (42)
- Amino Acid Mutations Essential to Production of an Altered PBP 2X Conferring High-Level β-Lactam Resistance in a Clinical Isolate of Streptococcus pneumoniae (2005) (41)
- Acquisition of Chloramphenicol Resistance by the Linearization and Integration of the Entire Staphylococcal Plasmid pC194 into the Chromosome of Streptococcus pneumoniae (2000) (41)
- Evernimicin (SCH27899) Inhibits a Novel Ribosome Target Site: Analysis of 23S Ribosomal DNA Mutants (2000) (41)
- Usefulness of C-Reactive Protein to Define Pneumococcal Conjugate Vaccine Efficacy in the Prevention of Pneumonia (2006) (41)
- Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study. (2017) (41)
- Use of Procalcitonin and C-Reactive Protein to Evaluate Vaccine Efficacy against Pneumonia (2005) (41)
- Systemic shigellosis in South Africa. (2012) (40)
- WORLDWIDE INCREASE IN PNEUMOCOCCAL ANTIBIOTIC RESISTANCE (1989) (40)
- Three predominant clones identified within penicillin-resistant South African isolates of Streptococcus pneumoniae. (1997) (40)
- Fluoroquinolone Resistance in Invasive Streptococcus pyogenes Isolates Due to Spontaneous Mutation and Horizontal Gene Transfer (2006) (40)
- Increased resistance to amikacin in a neonatal unit following intensive amikacin usage (1992) (39)
- Laboratory surveillance for Haemophilus influenzae type B meningococcal, and pneumococcal disease. Haemophilus Surveillance Working Group. (1999) (39)
- HIV and influenza virus infections are associated with increased blood pneumococcal load: a prospective, hospital-based observational study in South Africa, 2009-2011. (2014) (39)
- Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose. (2011) (39)
- Spread of the Spanish multi-resistant serotype 23F clone of Streptococcus pneumoniae to Seoul, Korea. (1997) (39)
- Invasive disease due to Haemophilus influenzae serotype b ten years after routine vaccination, South Africa, 2003-2009. (2012) (38)
- Increased Nasopharyngeal Density and Concurrent Carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Are Associated with Pneumonia in Febrile Children (2016) (38)
- Vaccines as tools against resistance: the example of pneumococcal conjugate vaccine. (2004) (37)
- HIV Infection and the Epidemiology of Invasive Pneumococcal Disease (IPD) in South African Adults and Older Children Prior to the Introduction of a Pneumococcal Conjugate Vaccine (PCV) (2016) (37)
- Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa (2017) (37)
- Neisseria meningitidis Intermediately Resistant to Penicillin and Causing Invasive Disease in South Africa in 2001 to 2005 (2008) (36)
- Neonatal typhoid fever. (1994) (36)
- Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae. (2000) (36)
- Clinical impact of antibiotic resistance in respiratory tract infections. (2007) (36)
- Antibiotic Susceptibility Patterns ofStreptococcus pneumoniae in China and Comparison of MICs by Agar Dilution and E-Test Methods (1998) (36)
- Long-term antibody levels and booster responses in South African children immunized with nonavalent pneumococcal conjugate vaccine. (2004) (35)
- Vaccination to reduce antimicrobial resistance. (2017) (35)
- The Relevance of a Novel Quantitative Assay to Detect up to 40 Major Streptococcus pneumoniae Serotypes Directly in Clinical Nasopharyngeal and Blood Specimens (2016) (35)
- Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents. (2003) (35)
- Impact of cotrimoxazole on non-susceptibility to antibiotics in Streptococcus pneumoniae carriage isolates among HIV-infected mineworkers in South Africa. (2008) (34)
- Community-acquired pneumonia in an adult due to a multiply-resistant pneumococcus. (1987) (33)
- Antibiotic non-susceptibility among Streptococcus pneumoniae and Haemophilus influenzae isolates identified in African cohorts: a meta-analysis of three decades of published studies. (2013) (33)
- Acquisition of Streptococcus pneumoniae in Pneumococcal Conjugate Vaccine-naïve South African Children and Their Mothers (2013) (33)
- Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa. (2008) (33)
- Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children (2013) (33)
- Contribution of vaccines to our understanding of pneumococcal disease (2011) (33)
- Clinical and Microbiological Features of Salmonella Meningitis in a South African Population, 2003-2013. (2015) (33)
- Site-Specific Mutagenesis Analysis of PBP 1A from a Penicillin-Cephalosporin-Resistant Pneumococcal Isolate (2003) (32)
- Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China. (2008) (32)
- Telithromycin Resistance in Streptococcus pneumoniae Is Conferred by a Deletion in the Leader Sequence of erm(B) That Increases rRNA Methylation (2007) (32)
- Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae (2015) (32)
- Prevalence of First-Step Mutants among Levofloxacin-Susceptible Invasive Isolates of Streptococcus pneumoniae in the United States (2006) (32)
- Herd protection induced by pneumococcal conjugate vaccine. (2014) (32)
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- Rationale for a hospital-based pneumococcal vaccine trial for HIV-seropositive South Africans. (2000) (1)
- Antibiotics for paediatric community-acquired pneumonia in resource-constrained settings (2020) (1)
- Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints (2022) (1)
- Regional considerations in the use of broad-spectrum quinolones (1998) (1)
- Advances in the management of penicillin-resistant pneumococcal meningitis. (1992) (1)
- Centres of excellence for academic medicine in South Africa. (1994) (1)
- Impact of Pneumococcal Conjugate Vaccine on Vaccine Serotype–Specific Pneumonia (2020) (1)
- The future of paediatric pneumococcal conjugate vaccines. (2017) (1)
- Antibiotic prescribing practices for common childhood illnesses in South Africa. (2003) (1)
- Antibiotic prophylaxis—Preventing severe infections and saving lives in poor countries with very high mortality risk (2018) (1)
- S48 Recent discoveries in prevention of pneumococcal disease (2007) (1)
- Efficacy and Safety of Conjugate Pneumococcal Vaccine in the Prevention of Pneumonia (2008) (1)
- A novel mosaic tetracycline resistance gene tet(S/M) detected in a multidrug-resistant pneumococcal CC230 lineage that underwent capsular switching in South Africa (2019) (1)
- A Retrospective Evaluation of Fluoroquinolone Antibacterial Selection in a U.S. Community Hospital (2004) (1)
- Spring Scrub Typhus , People ’ s Republic of China (2019) (1)
- International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease (2022) (1)
- 16th International Congress on Infectious Diseases (2013) (1)
- An evaluation of two indirect fluorescent antibody tests for the diagnosis of Legionnaire's disease in South Africa. (1990) (1)
- Bacterial enteritis of infancy and childhood in Soweto. (1986) (1)
- Serotype-specific Cardiac Involvement in Pneumococcal Pneumonia (2020) (1)
- Disk susceptibility testing of penicillin-resistant pneumococci (1988) (1)
- The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success (2012) (1)
- Pneumococcal infection and colonization in children and its impact on pneumococcal disease in adults (2010) (1)
- A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV (2022) (1)
- Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae the (2018) (1)
- Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011–2018 determined through whole-genome sequencing (2022) (1)
- The potential impact of the 13-valent conjugate pneumococcal vaccine on antibiotic resistance in pneumococci (2011) (1)
- Susceptibility of Bacillus anthracis to moxifloxacin (2005) (1)
- Vaccination to reduce antimicrobial (2018) (1)
- Impact of antimicrobial resistance and antibiotic choice on the outcome of pneumococcal meningitis. (1997) (1)
- Focus on TB. (2003) (1)
- Is Combination the Only Issue (2005) (0)
- Phylogeography and resistome of pneumococcal meningitis in West Africa before and after vaccine introduction (2021) (0)
- Epidemiology, control and treatment of multiresistant pneumococci. Discussion (1996) (0)
- Antimicrobial Susceptibility of Pneumococcal Isolates Causing Bacteremic Community-Acquired Pneumonia in Gauteng, South Africa. (2009) (0)
- The relationship between pneumococcal serotypes and antibiotic resistance (2013) (0)
- Emergence, Spread, and Extinction of Pathogenic Bacterial Clones (2008) (0)
- Conjugate Vaccines as Probes To Define the Burden of Pneumococcal and Haemophilus influenzae Type b Pneumonia as Well as the Role of Viruses in the Pathogenesis of Pneumonia (2007) (0)
- Global Infectious Diseases (2014) (0)
- Variable recombination dynamics during the emergence, transmission and ‘disarming’ of a multidrug-resistant pneumococcal clone (2014) (0)
- William of the Pneumococcus Chloramphenicol in Ribosomal Protein L 4 Oxazolidinones , Macrolides , and Novel Mechanism of Resistance to (2005) (0)
- Integrated pneumonia surveillance: pandemics and beyond (2022) (0)
- Unusual Multiply Resistant Pneumococci-Reply (1988) (0)
- Epidemiology and control of multiresistant enterococci. Discussion (1996) (0)
- Failures of beta-lactam therapy for invasive pneumococcal disease. (2004) (0)
- Correction: Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children (2014) (0)
- Increased Risk of Death in HIV-Infected Patients with Pneumococcal Meningitis, South Africa, 2003–2005 (2008) (0)
- Updates on Major ID: TB, Malaria, and Typhoid (2014) (0)
- The prevention of childhood pneumonia. (2006) (0)
- Eff ectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children : a case-control study (2017) (0)
- Pneumolysin in the Assembly of Biofilms Toxin Streptococcus pneumoniae Novel Role for the 2013 (0)
- Two cases of serotypeable and non-serotypeable variants of Streptococcus pneumoniae detected simultaneously during invasive disease (2016) (0)
- Streptococcus pneumoniae: Review of Factors Relevant to Development and Management of Fluoroquinolone Resistance in a Nursing Home Setting (2007) (0)
- Pneumonia vaccines for all who need them (2009) (0)
- CHAPTER 29 – Pneumococcal Infections (2011) (0)
- Comprar Pneumococcal Vaccines: The Impact of Conjugate Vaccine | Mary Barasi | 9781555814083 | Wiley (2008) (0)
- Pathogenesis and host ResPonse (0)
- Effects of Clarithromycin, at Sub-MIC Concentrations, on the Growth of Macrolide-Resistant Streptococcus pneumoniae (2010) (0)
- Pneumococcal carriage and sero-epidemiology studies to measure current and future pneumococcal conjugate vaccine effectiveness. (2022) (0)
- Author response: The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci (2021) (0)
- 1732 COLONY MORPHOLOGY OF PILIATED NEISSERIA MENINGITIDIS (2003) (0)
- an international DNA- based birth cohort study (2015) (0)
- SP8-1 Vaccination prevents resistance in pneumococcal infections (2013) (0)
- Carriage ofpenicillin resistant pneumococci (1986) (0)
- Neglected Tropical Disease Eradication (2015) (0)
- STRETOCOCCUS PNEUMONIAE RESPIRATORY TRACT INFECTION* (2002) (0)
- Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae. (2003) (0)
- [Complex choices in respiratory tract infections: the search for simple solutions]. (2007) (0)
- Development and Characterization of a Synthetic DNA, NUversa, to Be Used as a Standard in All Quantitative PCR Reactions for Molecular Pneumococcal Serotyping (2017) (0)
- Pneumococcal vaccination for acute otitis media. Commentary (2006) (0)
- Impact of Human Immunodeficiency Virus Tfrpe 1 Infection on the Epidemiology and Outcome of Bacterial Meningitis in South African Children (2004) (0)
- Pneumococcal diseases. (1998) (0)
- Public Health and Economic Impact of 7-valent Pneumococcal Conjugate Vaccination in an Influenza Pandemic in the US (2008) (0)
- Dynamics of Colonization and Recolonization of Streptococcus pneumoniae Strains in Healthy Peruvian Children (2016) (0)
- Fluoroquinolone treatment of pneumococcal infections (2006) (0)
- Adult pneumacoccal vaccination guideline (1999) (0)
- Erratum for Geno et al., “Pneumococcal Capsules and Their Types: Past, Present, and Future” (2020) (0)
- Long term serological response to Vi vaccine and protective immunity (1998) (0)
- Role of Antibody in Recovery from Severe Vaccinia Virus Infection (2010) (0)
- Consequences of increasing resistance to antimicrobial agents. Discussion (1998) (0)
- Impact of Conjugated Pneumococcal Vaccine on Influenza Morbidity (2009) (0)
- Detection of Pneumococcal Pneumonia in a Phase 3 Trial Comparing Oral Solithromycin Versus Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia in Adults (2015) (0)
- Lifelong antihypertensive therapy. (1980) (0)
- Respiratory Diseases: The Leading Killer (2017) (0)
- Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism (2020) (0)
- Implications of bacterial resistance for the use of beta-lactam agents in clinical practice. (1993) (0)
- Antimicrobials Resistance: Trends and Interventions (2003) (0)
- 2617. Increased Nasopharyngeal Pneumococcal Density During Asymptomatic Respiratory Virus Infection Is Associated with Subsequent Development of Acute Respiratory Illness (2019) (0)
- Trovafloxacin : A Viewpoint by Keith P. Klugman. (1997) (0)
- Chapter 30 – Pneumococcal Infections (2006) (0)
- COLONY MORPHOLOGY OF PILIATED (2003) (0)
- Factors associated with ceftriaxone non-susceptibility of Streptococcus pneumoniae: 2 (2014) (0)
- Lessons from 1918 and the current H1N1 pandemic on the role of bacterial infections during pandemic influenza (2010) (0)
- Trends in β-lactam resistance among enterobacteriaceae. Discussion (1998) (0)
- Explorer The case for launch of an international DNA-based birth cohort study (2017) (0)
- NOSOCOMIAL INVASIVE PNEUMOCOCCAL DISEASE (IPD) (2006) (0)
- Review 1: "Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics" (2020) (0)
- Genes and spectrum : The theoretical limits. Discussion (1998) (0)
- Antibiotic resistance: does it really matter? (1995) (0)
- Iconographies supplémentaires de l'article : Prevalence of maternal colonisation with group B streptococcus: a systematic review and meta-analysis (2016) (0)
- Leech Vol 61 (3) (1992) (0)
- Impact of PCV7 on Nasopharyngeal Density, Serotype Distribution and Antibiotic Resistance of Pneumococcal Strains Isolated from Peruvian Children (2017) (0)
- P9 Examination of AUICs for Streptococcus pneumoniae (SP) in patients with CAP failing to respond to outpatient β-lactams (BL) (2009) (0)
- Invasive candidiasis in the ICU--pathogenesis and management strategy. (1994) (0)
- Free Papers (2005) (0)
- Comparative Genomics of Disease and Carriage Serotype 1 Pneumococci (2022) (0)
- Impact Of Trivalent Influenza Vaccination Of Pregnant Women On Recurrent Respiratory Infections And Weight Gain In The First 6 Months Of Life (2015) (0)
- Antimicrobial Resistance—Fluoroquinolones and the Tiger's Tail (2006) (0)
- Emergence and Resurgence of Bacterial Infectious Diseases (2010) (0)
- Streptococcus pneumoniae respiratory tract infections (2001) (0)
- Pneumococcal conjugate vaccine--prospects for intervention in children. (1999) (0)
- Pneumococcal and Hib Conjugate Vaccines in the Developing World: If These are the Answers, What is the Question? (2004) (0)
- HIV and Influenza Infection Are Associated with Increased Blood Pneumococcal Load : a Prospective , Hospital-Based Observational Study in South Africa , 2009-2011 Running Title : HIV / influenza increase pneumococcal load (2013) (0)
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What Schools Are Affiliated With Keith P. Klugman?
Keith P. Klugman is affiliated with the following schools:
