Keith Poole
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Political Science
Keith Poole's Degrees
- PhD Political Science University of California, San Diego
- Masters Political Science University of California, San Diego
- Bachelors Political Science University of California, San Diego
Why Is Keith Poole Influential?
(Suggest an Edit or Addition)Keith Poole's Published Works
Published Works
- Efflux-mediated antimicrobial resistance. (2005) (1002)
- Pseudomonas Aeruginosa: Resistance to the Max (2011) (772)
- Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon (1993) (729)
- Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa (1995) (647)
- Efflux-mediated multiresistance in Gram-negative bacteria. (2004) (623)
- Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms. (2001) (477)
- Efflux pumps as antimicrobial resistance mechanisms (2007) (471)
- Overexpression of the mexC–mexD–oprJ efflux operon in nfxB‐type multidrug‐resistant strains of Pseudomonas aeruginosa (1996) (459)
- Bacterial stress responses as determinants of antimicrobial resistance. (2012) (434)
- Aminoglycoside Resistance in Pseudomonas aeruginosa (2005) (427)
- Mechanisms of bacterial biocide and antibiotic resistance (2002) (394)
- Efflux-Mediated Resistance to Fluoroquinolones in Gram-Negative Bacteria (2000) (341)
- Resistance to β-lactam antibiotics (2004) (333)
- Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression (1996) (325)
- Multidrug Efflux Pumps: Expression Patterns and Contribution to Antibiotic Resistance in Pseudomonas aeruginosa Biofilms (2001) (288)
- Multidrug resistance in Gram-negative bacteria. (2001) (276)
- Influence of the MexAB-OprM Multidrug Efflux System on Quorum Sensing in Pseudomonas aeruginosa (1998) (268)
- Multidrug Efflux Systems Play an Important Role in the Invasiveness of Pseudomonas aeruginosa (2002) (253)
- Multidrug efflux in Pseudomonas aeruginosa: components, mechanisms and clinical significance. (2001) (253)
- Iron acquisition and its control in Pseudomonas aeruginosa: many roads lead to Rome. (2003) (223)
- Cloning and sequence analysis of an EnvCD homologue in Pseudomonas aeruginosa: regulation by iron and possible involvement in the secretion of the siderophore pyoverdine (1993) (223)
- Role of the Multidrug Efflux Systems ofPseudomonas aeruginosa in Organic Solvent Tolerance (1998) (205)
- Quorum-sensing and siderophore biosynthesis in Pseudomonas aeruginosa: lasR/lasI mutants exhibit reduced pyoverdine biosynthesis. (1998) (196)
- Cloning and nucleotide sequence analysis of the ferripyoverdine receptor gene fpvA of Pseudomonas aeruginosa (1993) (183)
- Influence of Quorum Sensing and Iron on Twitching Motility and Biofilm Formation in Pseudomonas aeruginosa (2007) (182)
- Outer membranes and efflux: the path to multidrug resistance in Gram-negative bacteria. (2002) (181)
- Influence of Mutations in the mexR Repressor Gene on Expression of the MexA-MexB-OprM Multidrug Efflux System ofPseudomonas aeruginosa (2000) (180)
- Expression of Pseudomonas aeruginosa Multidrug Efflux Pumps MexA-MexB-OprM and MexC-MexD-OprJ in a Multidrug-Sensitive Escherichia coli Strain (1998) (180)
- Interplay between the MexA-MexB-OprM multidrug efflux system and the outer membrane barrier in the multiple antibiotic resistance of Pseudomonas aeruginosa. (2000) (179)
- Stress responses as determinants of antimicrobial resistance in Gram-negative bacteria. (2012) (178)
- At the Nexus of Antibiotics and Metals: The Impact of Cu and Zn on Antibiotic Activity and Resistance. (2017) (178)
- Contribution of the MexXY Multidrug Transporter to Aminoglycoside Resistance in Pseudomonas aeruginosa Clinical Isolates (2003) (175)
- Multiple Antibiotic Resistance inStenotrophomonas maltophilia: Involvement of a Multidrug Efflux System (2000) (174)
- Optimization of Meropenem Minimum Concentration/MIC Ratio To Suppress In Vitro Resistance of Pseudomonas aeruginosa (2005) (174)
- MexR Repressor of the mexAB-oprMMultidrug Efflux Operon of Pseudomonas aeruginosa: Identification of MexR Binding Sites in the mexA-mexRIntergenic Region (2001) (158)
- Interaction of aminoglycosides with the outer membranes and purified lipopolysaccharide and OmpF porin of Escherichia coli (1991) (155)
- MexAB‐OprM hyperexpression in NalC‐type multidrug‐resistant Pseudomonas aeruginosa: identification and characterization of the nalC gene encoding a repressor of PA3720‐PA3719 (2004) (155)
- Overcoming antimicrobial resistance by targeting resistance mechanisms (2001) (153)
- Mutations in PA2491 (mexS) Promote MexT-Dependent mexEF-oprN Expression and Multidrug Resistance in a Clinical Strain of Pseudomonas aeruginosa (2005) (152)
- Induction of the MexXY Efflux Pump in Pseudomonas aeruginosa Is Dependent on Drug-Ribosome Interaction (2005) (150)
- Outer membrane protein P of Pseudomonas aeruginosa: regulation by phosphate deficiency and formation of small anion-specific channels in lipid bilayer membranes (1982) (150)
- Antibiotic Inducibility of the MexXY Multidrug Efflux System of Pseudomonas aeruginosa: Involvement of the Antibiotic-Inducible PA5471 Gene Product (2006) (146)
- Inner membrane efflux components are responsible for beta-lactam specificity of multidrug efflux pumps in Pseudomonas aeruginosa (1997) (146)
- Contributions of MexAB-OprM and an EmrE Homolog to Intrinsic Resistance of Pseudomonas aeruginosa to Aminoglycosides and Dyes (2003) (145)
- Increase in Rhamnolipid Synthesis under Iron-Limiting Conditions Influences Surface Motility and Biofilm Formation in Pseudomonas aeruginosa (2010) (141)
- Molecular characterization of the hemolysin determinant of Serratia marcescens (1988) (137)
- Mutations in PA3574 (nalD) Lead to Increased MexAB-OprM Expression and Multidrug Resistance in Laboratory and Clinical Isolates of Pseudomonas aeruginosa (2005) (137)
- MexCD-OprJ Multidrug Efflux System of Pseudomonas aeruginosa: Involvement in Chlorhexidine Resistance and Induction by Membrane-Damaging Agents Dependent upon the AlgU Stress Response Sigma Factor (2008) (135)
- Crystal Structure of the MexR Repressor of themexRAB-oprM Multidrug Efflux Operon of Pseudomonas aeruginosa * (2002) (135)
- SmeC, an Outer Membrane Multidrug Efflux Protein of Stenotrophomonas maltophilia (2002) (134)
- SmeDEF Multidrug Efflux Pump Contributes to Intrinsic Multidrug Resistance in Stenotrophomonas maltophilia (2001) (126)
- Influence of the MexA-MexB-oprM multidrug efflux system on expression of the MexC-MexD-oprJ and MexE-MexF-oprN multidrug efflux systems in Pseudomonas aeruginosa. (2000) (125)
- Resistance to beta-lactam antibiotics. (2004) (124)
- β-Lactamase Inhibitors Are Substrates for the Multidrug Efflux Pumps of Pseudomonas aeruginosa (1998) (123)
- Enterobactin-mediated iron transport in Pseudomonas aeruginosa (1990) (123)
- PchR, a regulator of ferripyochelin receptor gene (fptA) expression in Pseudomonas aeruginosa, functions both as an activator and as a repressor (1996) (121)
- Oxidative Stress Induction of the MexXY Multidrug Efflux Genes and Promotion of Aminoglycoside Resistance Development in Pseudomonas aeruginosa (2010) (116)
- Cloning and sequence analysis of a gene (pchR) encoding an AraC family activator of pyochelin and ferripyochelin receptor synthesis in Pseudomonas aeruginosa (1993) (115)
- Cloning and characterization of the ferric enterobactin receptor gene (pfeA) of Pseudomonas aeruginosa (1993) (110)
- mexEF-oprN Multidrug Efflux Operon of Pseudomonas aeruginosa: Regulation by the MexT Activator in Response to Nitrosative Stress and Chloramphenicol (2010) (108)
- The outer membrane protein OprM of Pseudomonas aeruginosa is encoded by oprK of the mexA-mexB-oprK multidrug resistance operon (1995) (105)
- Efflux-Mediated Resistance to Fluoroquinolones in Gram-Positive Bacteria and the Mycobacteria (2000) (105)
- Iron‐free pyoverdin binds to its outer membrane receptor FpvA in Pseudomonas aeruginosa: a new mechanism for membrane iron transport (2001) (103)
- The pvc Gene Cluster ofPseudomonas aeruginosa: Role in Synthesis of the Pyoverdine Chromophore and Regulation by PtxR and PvdS (1999) (94)
- Differential Impact of MexB Mutations on Substrate Selectivity of the MexAB-OprM Multidrug Efflux Pump of Pseudomonas aeruginosa (2004) (94)
- Mechanisms of bacterial biocide and antibiotic resistance. (2002) (94)
- Contribution of Outer Membrane Efflux Protein OprM to Antibiotic Resistance in Pseudomonas aeruginosa Independent of MexAB (1998) (94)
- Bacterial Multidrug Efflux Pumps Serve Other Functions (2008) (93)
- Expression of the ferric enterobactin receptor (PfeA) of Pseudomonas aeruginosa: involvement of a two‐component regulatory system (1993) (92)
- Citrate-mediated iron uptake in Pseudomonas aeruginosa: involvement of the citrate-inducible FecA receptor and the FeoB ferrous iron transporter. (2009) (88)
- The MexR Repressor of the mexAB-oprM Multidrug Efflux Operon in Pseudomonas aeruginosa: Characterization of Mutations Compromising Activity (2002) (88)
- Monoclonal antibodies against Pseudomonas aeruginosa outer membrane antigens: isolation and characterization (1982) (86)
- nalD Encodes a Second Repressor of the mexAB-oprM Multidrug Efflux Operon of Pseudomonas aeruginosa (2006) (84)
- A second tonB gene in Pseudomonas aeruginosa is linked to the exbB and exbD genes. (2000) (83)
- Copurification of the FpvA ferric pyoverdin receptor of Pseudomonas aeruginosa with its iron-free ligand: implications for siderophore-mediated iron transport. (1999) (81)
- The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR (2008) (80)
- Iron regulation of Serratia marcescens hemolysin gene expression (1988) (80)
- Influence of the TonB Energy-Coupling Protein on Efflux-Mediated Multidrug Resistance in Pseudomonas aeruginosa (1998) (78)
- Pyoverdine-Mediated Regulation of FpvA Synthesis in Pseudomonas aeruginosa: Involvement of a Probable Extracytoplasmic-Function Sigma Factor, FpvI (2003) (78)
- Bacterial multidrug resistance--emphasis on efflux mechanisms and Pseudomonas aeruginosa. (1994) (73)
- PfeR, an enterobactin-responsive activator of ferric enterobactin receptor gene expression in Pseudomonas aeruginosa (1996) (73)
- Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia. (2003) (72)
- Assembly of the MexAB-OprM Multidrug Efflux System of Pseudomonas aeruginosa: Identification and Characterization of Mutations in mexA Compromising MexA Multimerization and Interaction with MexB (2004) (72)
- Novel pyoverdine biosynthesis gene(s) of Pseudomonas aeruginosa PAO. (1996) (72)
- Iron release from transferrin by pyoverdin and elastase from Pseudomonas aeruginosa (1994) (69)
- The Pseudomonas aeruginosa tonB gene encodes a novel TonB protein. (1996) (69)
- Pyochelin-mediated iron transport in Pseudomonas aeruginosa: involvement of a high-molecular-mass outer membrane protein (1991) (69)
- Phosphate transport in Pseudomonas aeruginosa. Involvement of a periplasmic phosphate-binding protein. (1984) (68)
- Pyoverdine-mediated iron transport in Pseudomonas aeruginosa: involvement of a high-molecular-mass outer membrane protein. (1991) (67)
- Fluoroquinolone susceptibilities of efflux-mediated multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Burkholderia cepacia. (2001) (65)
- Protein Modulator of Multidrug Efflux Gene Expression in Pseudomonas aeruginosa (2007) (64)
- FpvIR Control of fpvA Ferric Pyoverdine Receptor Gene Expression in Pseudomonas aeruginosa: Demonstration of an Interaction between FpvI and FpvR and Identification of Mutations in Each Compromising This Interaction (2005) (63)
- FpvA Receptor Involvement in Pyoverdine Biosynthesis in Pseudomonas aeruginosa (2002) (61)
- Organic solvent-tolerant mutants of Pseudomonas aeruginosa display multiple antibiotic resistance. (1999) (58)
- The MexA-MexB-OprM multidrug efflux system of Pseudomonas aeruginosa is growth-phase regulated. (1999) (57)
- Overcoming multidrug resistance in gram-negative bacteria. (2003) (56)
- Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ (2013) (55)
- Binding properties of pyochelin and structurally related molecules to FptA of Pseudomonas aeruginosa. (2006) (55)
- Stress responses as determinants of antimicrobial resistance in Pseudomonas aeruginosa: multidrug efflux and more. (2014) (54)
- Role of Phosphoglucomutase of Stenotrophomonasmaltophilia in Lipopolysaccharide Biosynthesis, Virulence, and Antibiotic Resistance (2003) (53)
- The ferripyoverdine receptor FpvA of Pseudomonas aeruginosa PAO1 recognizes the ferripyoverdines of P. aeruginosa PAO1 and P. fluorescens ATCC 13525. (1999) (51)
- Effect of multidrug resistance-conferring mutations on the fitness and virulence of Pseudomonas aeruginosa. (2011) (51)
- Mutational Analysis of the OprM Outer Membrane Component of the MexA-MexB-OprM Multidrug Efflux System ofPseudomonas aeruginosa (2001) (51)
- Influence of growth temperature and lipopolysaccharide on hemolytic activity of Serratia marcescens (1988) (51)
- Secretion of alkaline phosphatase and phsopholipase C in Pseudomonas aeruginosa is specific and does not involve an increase in outer membrane permeability (1983) (50)
- Functional characterization of the NfxB repressor of the mexCD-oprJ multidrug efflux operon of Pseudomonas aeruginosa. (2013) (50)
- Prevalence, mechanisms, and risk factors of carbapenem resistance in bloodstream isolates of Pseudomonas aeruginosa. (2007) (50)
- MexY-Promoted Aminoglycoside Resistance in Pseudomonas aeruginosa: Involvement of a Putative Proximal Binding Pocket in Aminoglycoside Recognition (2014) (49)
- Translational Control of the Antibiotic Inducibility of the PA5471 Gene Required for mexXY Multidrug Efflux Gene Expression in Pseudomonas aeruginosa (2009) (48)
- Determinants of Intrinsic Aminoglycoside Resistance in Pseudomonas aeruginosa (2012) (48)
- Assembly of the MexAB-OprM Multidrug Pump of Pseudomonas aeruginosa: Component Interactions Defined by the Study of Pump Mutant Suppressors (2007) (47)
- Phosphate-starvation-induced outer membrane proteins of members of the families Enterobacteriaceae and Pseudomonodaceae: demonstration of immunological cross-reactivity with an antiserum specific for porin protein P of Pseudomonas aeruginosa (1986) (46)
- Can efflux inhibitors really counter resistance (2006) (43)
- Lipopolysaccharide-free Escherichia coli OmpF and Pseudomonas aeruginosa protein P porins are functionally active in lipid bilayer membranes (1986) (40)
- Pentachlorophenol Induction of the Pseudomonas aeruginosa mexAB-oprM Efflux Operon: Involvement of Repressors NalC and MexR and the Antirepressor ArmR (2012) (39)
- Formation of the chromophore of the pyoverdine siderophores by an oxidative cascade. (2003) (37)
- Mutational Activation of the AmgRS Two-Component System in Aminoglycoside-Resistant Pseudomonas aeruginosa (2013) (36)
- AmgRS-mediated envelope stress-inducible expression of the mexXY multidrug efflux operon of Pseudomonas aeruginosa (2014) (35)
- Contribution of the MexAB-OprM multidrug efflux system to the beta-lactam resistance of penicillin-binding protein and beta-lactamase-derepressed mutants of Pseudomonas aeruginosa. (1999) (35)
- Reduced Expression of the rplU-rpmA Ribosomal Protein Operon in mexXY-Expressing Pan-Aminoglycoside-Resistant Mutants of Pseudomonas aeruginosa (2012) (34)
- An anion-selective channel from the Pseudomonas aeruginosa outer membrane (1983) (34)
- Mathematical modelling response of Pseudomonas aeruginosa to meropenem. (2007) (32)
- Interaction of the MexA and MexB Components of the MexAB-OprM Multidrug Efflux System of Pseudomonas aeruginosa: Identification of MexA Extragenic Suppressors of a T578I Mutation in MexB (2005) (29)
- EsrC, an envelope stress-regulated repressor of the mexCD-oprJ multidrug efflux operon in Pseudomonas aeruginosa. (2015) (26)
- Modification of the conductance, selectivity and concentration-dependent saturation of Pseudomonas aeruginosa protein P channels by chemical acetylation. (1983) (26)
- Conservation of the multidrug resistance efflux gene oprM in Pseudomonas aeruginosa (1997) (25)
- Editorial: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria (2016) (24)
- Mutational Analysis of the TonB1 Energy Coupler of Pseudomonas aeruginosa (2002) (22)
- Influence of OprM expression on multiple antibiotic resistance in Pseudomonas aeruginosa (1997) (21)
- FpvA-Mediated Ferric Pyoverdine Uptake in Pseudomonas aeruginosa: Identification of Aromatic Residues in FpvA Implicated in Ferric Pyoverdine Binding and Transport (2005) (20)
- Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System (2016) (17)
- OuterMembraneProtein PofPseudomonas aeruginosa: Regulation byPhosphate Deficiency andFormation ofSmall Anion-Specific Channels inLipid Bilayer Membranes (1982) (17)
- Mechanisms of antimicrobial resistance: opportunities for new targeted therapies (2005) (16)
- Differential Effects of Mutations in tonB1 on Intrinsic Multidrug Resistance and Iron Acquisition in Pseudomonas aeruginosa (2002) (15)
- Mutations in PA 3574 ( nalD ) Lead to Increased MexAB-OprM Expression and Multidrug Resistance in Laboratory and Clinical Isolates of Pseudomonas aeruginosa (2005) (13)
- Polymyxin Susceptibility in Pseudomonas aeruginosa Linked to the MexXY-OprM Multidrug Efflux System (2015) (12)
- Aminoglycoside-inducible expression of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: Involvement of the envelope stress-responsive AmgRS two-component system (2018) (12)
- Phosphate-selective porins from the outer membranes of fluorescent Pseudomonas sp. (1987) (11)
- Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa (2018) (11)
- Uninhibited antibiotic target discovery via chemical genetics (2004) (11)
- Meropenem potentiation of aminoglycoside activity against Pseudomonas aeruginosa: involvement of the MexXY-OprM multidrug efflux system (2018) (10)
- Characterization and Chemical Modification of Small Anion Specific Channels formed in Lipid Bilayer Membranes by Outer Membrane Protein P or Pseudomonas aeruginosa. (1984) (9)
- Insertion Mutagenesis of the Ferric Pyoverdine Receptor FpvA ofPseudomonas aeruginosa: Identification of Permissive Sites and a Region Important for Ligand Binding (1998) (8)
- The aminoglycoside resistance-promoting AmgRS envelope stress-responsive two-component system in Pseudomonas aeruginosa is zinc-activated and protects cells from zinc-promoted membrane damage. (2019) (7)
- Antimicrobial Drug Efflux Systems as Components of Bacterial Stress Responses (2016) (5)
- 2.9. Bacterial Stress Responses as Determinants of Antimicrobial Resistance (2016) (5)
- Influence of Mutations in the mexR Repressor Gene on Expression of the MexA-MexB-OprM Multidrug Efflux System of Pseudomonas aeruginosa (2000) (3)
- Antimicrobial and Stress Resistance (2007) (3)
- Isolation of a Tn501 insertion mutant lacking porin protein P of Pseudomonas aeruginosa (1986) (3)
- Rifampicin potentiation of aminoglycoside activity against cystic fibrosis isolates of Pseudomonas aeruginosa (2017) (3)
- Assessing the activity of bacterial multidrug efflux pumps. (2001) (2)
- Mechanotransduction pathways and relevance to human OA (2019) (1)
- P CHANNELS BY CHEMICAL ACETYLATION (2002) (0)
- Cloning and Sequence Analysis of a Gene (pchR) Encoding an AraC Family Activator of Pyochelin and Ferripyochelin Receptor Synthesis in Pseudomonas aerugmnosa (2003) (0)
- Nitrosylation Responses and Protein Nitration and K 12 Elicits Expression of Oxidative Stress Escherichia coli Peroxynitrite Toxicity in Microbiology : (2010) (0)
- Structure-guided disruption of the pseudopilus tip complex inhibits Type II secretion in Pseudomonas aeruginosa (2018) (0)
- IronTransport inPseudomonas aeruginosa (1990) (0)
- Involvement of a Multidrug Efflux System : Stenotrophomonas maltophilia Multiple Antibiotic Resistance in (2000) (0)
- AN ANION-SELECTIVE CHANNEL FROM THE PSEUDOMONAS AER UGINOSA (2002) (0)
- MINIREVIEW Efflux-Mediated Resistance to Fluoroquinolones in Gram-Negative Bacteria (2000) (0)
- The crystal structure of minor pseudopilin binary complex of XcpV and XcpW from the Type 2 secretion system of Pseudomonas aeruginosa (2016) (0)
- MINIREVIEW Aminoglycoside Resistance in Pseudomonas aeruginosa (2005) (0)
- NOTES nalD Encodes a Second Repressor of the mexAB-oprM Multidrug Efflux Operon of Pseudomonas aeruginosa (cid:1) (2006) (0)
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