Keith Yamamoto
#21,266
Most Influential Person Now
American biochemist
Keith Yamamoto's AcademicInfluence.com Rankings
Keith Yamamotobiology Degrees
Biology
#923
World Rank
#1613
Historical Rank
#494
USA Rank
Molecular Biology
#165
World Rank
#169
Historical Rank
#85
USA Rank
Biochemistry
#457
World Rank
#539
Historical Rank
#166
USA Rank
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Biology
Keith Yamamoto's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Keith Yamamoto Influential?
(Suggest an Edit or Addition)According to Wikipedia, Keith R. Yamamoto is vice chancellor of Science Policy and Strategy and professor of Cellular and Molecular Pharmacology at the University of California, San Francisco, . He is known for his Molecular Biology and Biochemistry research on nuclear receptors and his involvement in science policy and precision medicine.
Keith Yamamoto's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Two signals mediate hormone‐dependent nuclear localization of the glucocorticoid receptor. (1987) (920)
- Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids (2007) (788)
- Reduced levels of hsp90 compromise steroid receptor action in vivo (1990) (780)
- DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity (2009) (661)
- Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA (1986) (634)
- Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro (1985) (568)
- Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region (1983) (566)
- A prudent path forward for genomic engineering and germline gene modification (2015) (565)
- DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo (1983) (549)
- Allosteric effects of DNA on transcriptional regulators (1998) (495)
- Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells (1989) (456)
- Biological Regulation and Development (1982) (451)
- The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain (1988) (434)
- Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones (2002) (426)
- Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element (1984) (390)
- Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegans (2005) (389)
- Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement (1987) (378)
- A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor (1988) (371)
- Glucocorticoid regulation of the circadian clock modulates glucose homeostasis (2009) (354)
- Cell- and gene-specific regulation of primary target genes by the androgen receptor. (2007) (348)
- Glucocorticoid receptor control of transcription: precision and plasticity via allostery (2017) (329)
- Determinants of Cell- and Gene-Specific Transcriptional Regulation by the Glucocorticoid Receptor (2007) (327)
- Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes. (2004) (316)
- Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. (2010) (295)
- Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. (2009) (274)
- Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells (1984) (267)
- A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. (2005) (258)
- Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor (2003) (243)
- A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans. (2006) (241)
- The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression. (2005) (237)
- Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action (1975) (237)
- Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts (2002) (223)
- Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors α and β (2003) (222)
- An affective disorder in zebrafish with mutation of the glucocorticoid receptor (2012) (199)
- Integrated Biology and Undergraduate Science Education: A New Biology Education for the Twenty-First Century? (2010) (197)
- Importin 7 and Importin α/Importin β Are Nuclear Import Receptors for the Glucocorticoid Receptor (2004) (192)
- Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects (2006) (189)
- Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase‐3 response element that mediates regulation by phorbol esters and hormones (2001) (178)
- Metabolic gatekeeper function of B-lymphoid transcription factors (2016) (154)
- GLOBAL ALLIANCE FOR GENOMICS AND HEALTH (2015) (154)
- The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals (2013) (148)
- Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro. (2008) (139)
- An FK506-sensitive Transporter Selectively Decreases Intracellular Levels and Potency of Steroid Hormones* (1996) (129)
- The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites (1975) (126)
- Reciprocal intronic and exonic histone modification regions in humans (2010) (121)
- Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. (2004) (119)
- Three Amino Acid Substitutions Selectively Disrupt the Activation but Not the Repression Function of the Glucocorticoid Receptor N Terminus* (1997) (119)
- Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans (2014) (115)
- Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. (2004) (114)
- Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes (2014) (110)
- The Mediator Subunit MDT-15 Confers Metabolic Adaptation to Ingested Material (2008) (101)
- Precision medicine: Beyond the inflection point (2015) (98)
- Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network (2010) (98)
- Glucocorticoid Receptor Transcriptional Activity Determined by Spacing of Receptor and Nonreceptor DNA Sites* (1998) (96)
- Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity. (2006) (95)
- Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes (2008) (94)
- Glucocorticoid regulation of protein processing and compartmentalization (1982) (94)
- Non-competitive androgen receptor inhibition in vitro and in vivo (2009) (93)
- Mammary tumor virus DNA contains sequences required for its hormone-regulated transcription (1981) (91)
- An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors* (1999) (91)
- Nuclear hormone receptors in nematodes: Evolution and function (2011) (82)
- Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate* (2011) (82)
- The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast (1990) (81)
- A Coactivator Role of CARM1 in the Dysregulation of β-Catenin Activity in Colorectal Cancer Cell Growth and Gene Expression (2011) (79)
- Identification of C. elegans DAF-12-binding sites, response elements, and target genes. (2004) (73)
- Multiple specific binding sites for purified glucocorticoid receptors on mammary tumor virus DNA (1982) (72)
- Infection of cultured rat hepatoma cells by mouse mammary tumor virus (1977) (66)
- 13 Modulation of Steroid Receptor Signal Transduction by Heat Shock Proteins (1994) (66)
- New and improved proteomics technologies for understanding complex biological systems: Addressing a grand challenge in the life sciences (2012) (61)
- The Ligand Binding Domain Controls Glucocorticoid Receptor Dynamics Independent of Ligand Release (2007) (61)
- Leveraging Crowdsourcing to Facilitate the Discovery of New Medicines (2011) (61)
- Mouse mammary tumor virus DNA in infected rat cells: Characterization of unintegrated forms (1977) (55)
- A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms (2013) (55)
- Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner (2014) (50)
- A New Era in the Ethics of Human Embryonic Stem Cell Research (2005) (49)
- Cross Talk between Glucocorticoid and Estrogen Receptors Occurs at a Subset of Proinflammatory Genes (2011) (48)
- Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation (2016) (43)
- Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms. (2015) (43)
- Informed consent in human oocyte, embryo, and embryonic stem cell research. (2004) (42)
- Sumoylated NHR-25/NR5A Regulates Cell Fate during C. elegans Vulval Development (2013) (41)
- A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development. (1995) (38)
- Occupancy of chromatin organizers in the Epstein-Barr virus genome. (2011) (37)
- The Caenorhabditis elegans Ortholog of TRAP240, CeTRAP240/let-19, Selectively Modulates Gene Expression and Is Essential for Embryogenesis* (2004) (36)
- Internship Experiences Contribute to Confident Career Decision Making for Doctoral Students in the Life Sciences (2018) (35)
- Modular Structure of Glucocorticoid Receptor Domains Is Not Equivalent to Functional Independence (1996) (34)
- Time for NIH to lead on data sharing (2020) (33)
- The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner (2011) (33)
- Consent from Donors for Embryo and Stem Cell Research (2003) (31)
- Defects in the C. elegans acyl-CoA Synthase, acs-3, and Nuclear Hormone Receptor, nhr-25, Cause Sensitivity to Distinct, but Overlapping Stresses (2014) (29)
- Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)* (2016) (27)
- More fingers in hand (1988) (27)
- Gene Wars: Military Control over the New Genetic Technologies (1988) (26)
- Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action (2013) (25)
- Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia (2020) (20)
- 43 Combinatorial Regulation at a Mammalian Composite Response Element (1992) (17)
- Identification of the metal coordinating residues in the DNA binding domain of the glucocorticoid receptor by 113Cd‐1H heteronuclear NMR spectroscopy (1991) (15)
- A New Tool for Inducible Gene Expression in Caenorhabditis elegans (2018) (12)
- Realizing the Full Potential of Precision Medicine in Health and Health Care: A Vital Direction for Health and Health Care (2016) (10)
- Time to Play Ball (2013) (7)
- A Conceptual View of Transcriptional Regulation (1989) (7)
- Transcriptional Enhancement by Specific Regulatory Protein – DNA Complexes (1984) (7)
- Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations (2016) (7)
- Bankrolling stem-cell research with California dollars. (2004) (7)
- Commentary: Team science. (2013) (7)
- Medicine. Consent from donors for embryo and stem cell research. (2003) (6)
- 11 – Glucocorticoid Regulation of Mammary Tumor Virus Gene Expression (1978) (6)
- Overlapping but Separable Determinants of DNA Binding and Nuclear Localization Map to the C-terminal End of the Caenorhabditis elegans DAF-12 DNA Binding Domain* (2005) (5)
- CHAPTER 9 – Integrated Mammary Tumor Virus Genes: Transcriptional Regulation by Glucocorticoids and Specific Effects on Host Gene Expression (1978) (5)
- Glucocorticoid receptor collaborates with pioneer factors and AP-1 to execute genome-wide regulation (2021) (4)
- Biological Regulation and Development: Molecular Organization and Cell Function (2013) (3)
- Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes (2014) (3)
- Signaling and Regulation A Coactivator Role of CARM 1 in the Dysregulation of b-Catenin Activity in Colorectal Cancer Cell Growth and Gene Expression (2011) (3)
- Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors (2018) (2)
- Definition of alleles and altered regulatory motifs across Cas9-edited cell populations (2019) (2)
- SUMO as a nuclear hormone receptor effector (2014) (2)
- LEM 1 , an ATP-binding-cassette transporter , selectively modulates the biological potency of steroid hormones ( glucocorticoid receptor / yeast / PDR 5 / STSI ) (2005) (1)
- 1. Complementation analysis of steroid hormone action (1975) (1)
- SUMO as a nuclear hormone receptor effector New insights into combinatorial transcriptional regulation (2014) (1)
- Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression (2016) (1)
- Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements (2021) (1)
- Isolation ofHsp9Omutants byscreening fordecreased steroid receptor function (1993) (1)
- Hospital merger leaves clinical science intact (1999) (1)
- Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement (1987) (1)
- Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions (2016) (1)
- Abstracts of papers presented at the 1997 Meeting on Mechanisms of Eukaryotic Transcription, August 27-August 31/ arranged by Nouria Hernandez, Robert Kingston, Keith Yamamoto (1997) (0)
- Age-dependent Alterations ofc-fos andGrowth Regulation inHumanFibroblasts Expressing the (1996) (0)
- Abstracts of papers presented at the Cold Spring Harbor Meeting on Cancer Cells : regulation of eukaryotic mRNA transcription, September 6-September 10, 1989 (1989) (0)
- Mechanisms of Eukaryotic Transcription : abstracts of papers presented at the Cold Spring Harbor Meeting on Cancer Cells, August 30-Spetember 3, 1995 (1995) (0)
- Letter from Keith R. Yamamoto to Harold Varmus (1978) (0)
- Genetic exploration of a nuclear receptor transcriptional regulatory complex (2020) (0)
- Letter from Keith R. Yamamoto to Paul Warenski (c/o U. S. Representative Wayne Owens) (1988) (0)
- A Role for Hsp9O in Retinoid Receptor Signal Transduction (2003) (0)
- Institutions’ role in trainee success (2023) (0)
- Proinflammatory Genes Estrogen Receptors Occurs at a Subset of Cross Talk between Glucocorticoid and (2011) (0)
- androgen receptor Cell-and gene-specific regulation of primary target genes by the data (2007) (0)
- Decision letter: Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis (2021) (0)
- Induction ofCarcinoma CellMigration onVitronectin byNF-KB-dependent GeneExpression (1995) (0)
- Molecular analysis of the glucocorticoid receptor (1989) (0)
- The Motivating INformed Decisions (MINDs) Program – The University of California San Francisco BEST program for career exploration (2020) (0)
- B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling (2015) (0)
- Transgenic MicewithReduced NumbersofFunctional SpermReceptors onTheirEggsReproduce Normally (1995) (0)
- Metabolic gatekeeper function of B-lymphoid transcription factors (2017) (0)
- into a safe harbor locus in the human genome isogenic settings using zinc finger nuclease-driven transgenesis Functional genomics , proteomics , and regulatory DNA analysis in Material Supplemental (2010) (0)
- Mechanisms of Eukaryotic Transcription : Abstracts of papers presented at the Cold Spring Harbor Meeting on Cancer Cells, September 1-September 5, 1993 (1993) (0)
- Cloning ofMid-G1 SerumResponse Genesand Identification ofaSubset Regulated byConditional mycExpression (1994) (0)
- The glucocorticoid receptor ligand-binding domain confers drug-gated protein regulation in C. elegans (2018) (0)
- Altered ShapeandCellCycleCharacteristics of Fibroblasts Expressing theE2F1Transcription Factor (1994) (0)
- Protein toItsNuclear Form: Dependence onHormoneandDNA (1972) (0)
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What Schools Are Affiliated With Keith Yamamoto?
Keith Yamamoto is affiliated with the following schools:
