Kenneth Offit
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American cancer geneticist and oncologist
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Medical Biology
Why Is Kenneth Offit Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kenneth Offit is an American cancer geneticist and oncologist. He is currently Chief of the Clinical Genetics Service and the Robert and Kate Niehaus Chair in Inherited Cancer Genomics at Memorial Sloan Kettering Cancer Center. Offit is also a member of the Program in Cancer Biology and Genetics at the Sloan-Kettering Institute, Professor of Medicine and Healthcare Policy and Research at Weill Cornell Medical College, and a member of both the Board of Scientific Counselors of the National Cancer Institute and the Evaluation of Genomic Applications in Practice and Prevention working group of the U.S. Centers for Disease Control.
Kenneth Offit's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. (2016) (1060)
- Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation. (2002) (1035)
- Recommendations for follow-up care of individuals with an inherited predisposition to Cancer. II. BRCA1 and BRCA2 (1997) (939)
- The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds (1996) (866)
- Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. (1993) (690)
- Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC (1997) (686)
- Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. (1997) (656)
- Genetic/familial high-risk assessment: breast and ovarian. (2010) (648)
- Germline mutations in BAP1 predispose to melanocytic tumors (2011) (635)
- Network modeling links breast cancer susceptibility and centrosome dysfunction. (2007) (628)
- Recommendations for Follow-up Care of Individuals With an Inherited Predisposition to Cancer: I. Hereditary Nonpolyposis Colon Cancer (1997) (613)
- BCL-6 protein is expressed in germinal-center B cells. (1995) (585)
- Integrative Clinical Genomics of Metastatic Cancer (2017) (574)
- Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes (2018) (559)
- Hereditary cancer predisposition syndromes. (2005) (555)
- NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017. (2017) (554)
- Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer (2013) (534)
- Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study. (2008) (527)
- Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants (2015) (471)
- Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. (1998) (468)
- Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study. (2005) (456)
- Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) (2011) (447)
- Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers. (2002) (435)
- Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. Cancer Genetics Studies Consortium. (1997) (419)
- BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing. (1997) (410)
- Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk (2013) (405)
- Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. (2015) (390)
- p53 mutations are associated with histologic transformation of follicular lymphoma. (1993) (389)
- The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1% (1996) (383)
- Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma. (1994) (378)
- Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. (2002) (369)
- Genetic/familial high-risk assessment: breast and ovarian. (2010) (366)
- Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma. (1995) (365)
- A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population (2010) (357)
- Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. (2021) (346)
- Chromosomal and gene amplification in diffuse large B-cell lymphoma. (1998) (335)
- A germline JAK2 SNP is associated with predisposition to the development of JAK2V617F-positive myeloproliferative neoplasms (2009) (331)
- BRCA-associated breast cancer in young women. (1998) (323)
- Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing (2017) (321)
- MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner. (2006) (320)
- Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. (1998) (316)
- A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment (2003) (315)
- Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer (1996) (315)
- Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families (1996) (313)
- Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making. (2017) (309)
- Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015. (2016) (306)
- Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33 (2008) (304)
- Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma. (1994) (303)
- Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. (2006) (301)
- Two Decades After BRCA: Setting Paradigms in Personalized Cancer Care and Prevention (2014) (296)
- Prediction of germline mutations and cancer risk in the Lynch syndrome. (2006) (293)
- Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer. (2019) (289)
- NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020. (2020) (281)
- Discovery of common and rare genetic risk variants for colorectal cancer (2018) (279)
- RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. (2007) (276)
- Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: An update (2006) (270)
- Germline BRCA Mutations Denote a Clinicopathologic Subset of Prostate Cancer (2010) (269)
- The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers (2016) (267)
- Counselling framework for moderate-penetrance cancer-susceptibility mutations (2016) (264)
- A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia (2013) (253)
- The "duty to warn" a patient's family members about hereditary disease risks. (2004) (251)
- Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. (2016) (250)
- Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer (2017) (244)
- Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study. (2007) (243)
- Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation (2002) (235)
- Tumour lineage shapes BRCA-mediated phenotypes (2019) (235)
- The lifetime risks of breast cancer in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations. (2001) (234)
- Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: clinical correlations. (1991) (230)
- Genetics, genomics, and cancer risk assessment (2011) (229)
- Cancer therapy shapes the fitness landscape of clonal hematopoiesis (2020) (218)
- American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility. (2010) (214)
- Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers (2017) (211)
- Value of Histopathology in Predicting Microsatellite Instability in Hereditary Nonpolyposis Colorectal Cancer and Sporadic Colorectal Cancer (2003) (209)
- Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma. (1992) (209)
- Multiplex genetic testing for cancer susceptibility: out on the high wire without a net? (2013) (209)
- BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma. (2009) (208)
- Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations (2018) (206)
- BLM Heterozygosity and the Risk of Colorectal Cancer (2002) (199)
- Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations. (2003) (199)
- 6q deletions define distinct clinico-pathologic subsets of non-Hodgkin's lymphoma. (1993) (198)
- The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health–Centers for Disease Control and Prevention Multidisciplinary Workshop (2009) (196)
- Clinical practice. Management of an inherited predisposition to breast cancer. (2007) (196)
- Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families. (2019) (196)
- Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. (2010) (196)
- Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels. (2016) (190)
- Genome-wide Association Study Identifies Multiple Risk Loci for Chronic Lymphocytic Leukemia (2013) (190)
- Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia. (2003) (189)
- BRCA Mutations and Risk of Prostate Cancer in Ashkenazi Jews (2004) (189)
- Cytogenetic analysis of 434 consecutively ascertained specimens of non‐Hodgkin's lymphoma: Correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment (1991) (186)
- Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers (2005) (183)
- Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations. (2002) (180)
- Low incidence of BRCA2 mutations in breast carcinoma and other cancers (1996) (179)
- Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study. (1996) (177)
- Identification of six new susceptibility loci for invasive epithelial ovarian cancer (2014) (176)
- Prevention and management of hereditary breast cancer. (2005) (174)
- Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer (2011) (174)
- Personalized medicine: new genomics, old lessons (2011) (172)
- Breast conservation therapy for invasive breast cancer in Ashkenazi women with BRCA gene founder mutations. (1999) (172)
- ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes (2006) (171)
- Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations. (2016) (168)
- A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers. (2001) (167)
- Identification of germline genetic mutations in patients with pancreatic cancer (2015) (166)
- Psychosocial predictors of BRCA counseling and testing decisions among urban African-American women. (2002) (166)
- Referral for cancer genetics consultation: a review and compilation of risk assessment criteria (2004) (160)
- Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors (2013) (159)
- Decision-Making About Genetic Testing Among Women at Familial Risk for Breast Cancer (1997) (158)
- Genetic/familial high-risk assessment: breast and ovarian, version 1.2014. (2014) (158)
- TβR-I(6A) Is a Candidate Tumor Susceptibility Allele (1999) (158)
- Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma (2011) (156)
- Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (154)
- Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. (2016) (154)
- Immunohistochemistry as First-line Screening for Detecting Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome: A 2-antibody Panel May be as Predictive as a 4-antibody Panel (2009) (154)
- Value of Immunohistochemical Detection of DNA Mismatch Repair Proteins in Predicting Germline Mutation in Hereditary Colorectal Neoplasms (2005) (153)
- Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms (2018) (151)
- Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. (2008) (147)
- Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins (2014) (146)
- p53 overexpression as a marker of poor prognosis in mantle cell lymphomas with t(11;14)(q13;q32). (1995) (143)
- Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores (2017) (142)
- Germline BRCA1 185delAG mutations in Jewish women with breast cancer (1996) (142)
- Frequency of CHEK2*1100delC in New York breast cancer cases and controls (2003) (141)
- Genome-wide association study identifies multiple susceptibility loci for diffuse large B-cell lymphoma (2014) (140)
- Quality of life in women at risk for ovarian cancer who have undergone risk-reducing oophorectomy. (2003) (139)
- Two‐Stage Designs for Gene–Disease Association Studies (2002) (136)
- Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing (2016) (134)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. (2015) (133)
- MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas. (1991) (132)
- BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2 (2018) (131)
- REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. (1996) (131)
- Appropriateness of breast‐conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2 (2005) (130)
- The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. (2002) (129)
- Risk of endometrial carcinoma associated with BRCA mutation. (2001) (126)
- Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia (2015) (125)
- Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. (2009) (124)
- Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population. (2005) (123)
- Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 (2016) (122)
- t(9;14)(p13;q32) denotes a subset of low-grade non-Hodgkin's lymphoma with plasmacytoid differentiation. (1992) (120)
- Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk (2013) (120)
- Quantitating familial cancer risk: a resource for clinical oncologists. (1994) (119)
- Leukemic differentiation of a mediastinal germ cell tumor (1989) (118)
- A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome (2013) (117)
- Cancer genomics and inherited risk. (2014) (117)
- Estrogen Receptor Genotypes and Haplotypes Associated with Breast Cancer Risk (2004) (117)
- A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants (2010) (113)
- Genomic profiles for disease risk: predictive or premature? (2008) (113)
- ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes. (2006) (112)
- Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk. (2008) (112)
- DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2014) (112)
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2019) (110)
- TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies. (2003) (110)
- Absence of premalignant histologic, molecular, or cell biologic alterations in prophylactic oophorectomy specimens from BRCA1 heterozygotes (2000) (110)
- Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma (2010) (109)
- Cancer genetic testing and assisted reproduction. (2006) (108)
- Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia (2016) (107)
- Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. (2016) (107)
- REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma (1996) (106)
- Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium (2002) (106)
- Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer (2012) (105)
- Molecular genetic characterization of BRCA1- and BRCA2-linked hereditary ovarian cancers. (1998) (104)
- Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract. (1998) (104)
- Pleomorphic Characteristics of a Germ-Line KIT Mutation in a Large Kindred with Gastrointestinal Stromal Tumors, Hyperpigmentation, and Dysphagia (2004) (103)
- The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk (2017) (103)
- 18q21 rearrangement in diffuse large cell lymphoma: incidence and clinical significance (1989) (102)
- Novel Common Genetic Susceptibility Loci for Colorectal Cancer (2018) (102)
- Cytogenetic analysis of chimerism and leukemia relapse in chronic myelogenous leukemia patients after T cell-depleted bone marrow transplantation. (1990) (101)
- Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (2011) (101)
- Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. (2014) (101)
- Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma (2018) (101)
- Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing (2017) (100)
- Relative contributions of BRCA1 and BRCA2 mutations to “triple-negative” breast cancer in Ashkenazi Women (2011) (97)
- Heterogenic Loss of the Wild-Type BRCA Allele in Human Breast Tumorigenesis (2007) (97)
- BRCA-associated breast cancer: absence of a characteristic immunophenotype. (1998) (96)
- The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group. (2000) (96)
- TGFBR1*6A and cancer: a meta-analysis of 12 case-control studies. (2004) (96)
- Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (95)
- Intermediate- to high-grade histology of lymphomas carrying t(14;18) is associated with additional nonrandom chromosome changes. (1987) (95)
- t(3;22)(q27;q11): a novel translocation associated with diffuse non- Hodgkin's lymphoma [see comments] (1989) (94)
- Survival in epithelial ovarian cancer: a multivariate analysis incorporating BRCA mutation status and platinum sensitivity. (2011) (93)
- Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers (2012) (92)
- Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. (2011) (90)
- Genome-wide association studies of cancer. (2010) (90)
- Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations (2003) (89)
- Incidence of non-founder BRCA1 and BRCA2 mutations in high risk Ashkenazi breast and ovarian cancer families (2002) (88)
- Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 (2016) (84)
- TbetaR-I(6A) is a candidate tumor susceptibility allele. (1999) (82)
- Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk. (2005) (82)
- Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. (2011) (82)
- FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor. (2015) (82)
- Preimplantation genetic diagnosis for cancer syndromes: a new challenge for preventive medicine. (2006) (81)
- Improved survival for BRCA2‐associated serous ovarian cancer compared with both BRCA‐negative and BRCA1‐associated serous ovarian cancer (2012) (80)
- Risk of ovarian cancer in BRCA1 and BRCA2 mutation-negative hereditary breast cancer families. (2005) (78)
- Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer. (2019) (78)
- Clinical and morphologic features of B-cell small lymphocytic lymphoma with del(6)(q21q23). (1994) (77)
- Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia (2017) (77)
- BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. (2016) (76)
- Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis (2020) (76)
- Similar patterns of genomic alterations characterize primary mediastinal large‐B‐cell lymphoma and diffuse large‐B‐cell lymphoma (2002) (75)
- Chromosomal aberrations in non-Hodgkin's lymphoma. Biologic and clinical correlations. (1991) (74)
- Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk. (2020) (74)
- Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer. (2004) (74)
- Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2019) (74)
- Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene (2009) (73)
- Effect of Mammography on Breast Cancer Risk in Women with Mutations in BRCA1 or BRCA2 (2006) (73)
- Clinical Cancer Genetics: Risk Counseling and Management (1998) (72)
- Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer (2017) (70)
- Identification of genetic lesions associated with diffuse large-cell lymphoma. (1994) (68)
- Shared heritability and functional enrichment across six solid cancers (2018) (67)
- Blood Biomarker Levels to Aid Discovery of Cancer-Related Single-Nucleotide Polymorphisms: Kallikreins and Prostate Cancer (2010) (66)
- Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses (2019) (66)
- Translating genomics in cancer care. (2013) (66)
- Colorectal cancer risk in individuals with biallelic or monoallelic mutations of MYH (2005) (64)
- Familial Kidney Cancer: Implications of New Syndromes and Molecular Insights. (2019) (64)
- Recommendations from the EGAPP Working Group: can testing of tumor tissue for mutations in EGFR pathway downstream effector genes in patients with metastatic colorectal cancer improve health outcomes by guiding decisions regarding anti-EGFR therapy? (2013) (64)
- Polymorphisms of ADIPOQ and ADIPOR1 and prostate cancer risk. (2011) (63)
- Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium (2014) (62)
- Revealing the incidentalome when targeting the tumor genome. (2013) (62)
- Susceptibility Loci Associated with Prostate Cancer Progression and Mortality (2010) (61)
- Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants (2020) (60)
- Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2012) (60)
- Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (60)
- MSH6 germline mutations are rare in colorectal cancer families (2003) (58)
- Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus (2016) (58)
- Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers (2014) (58)
- Breast MRI for women with hereditary cancer risk. (2004) (58)
- Involvement of BCL6 in chromosomal aberrations affecting band 3q27 in B‐cell non‐Hodgkin lymphoma (1998) (57)
- Breast cancer risks in individuals testing negative for a known family mutation in BRCA1 or BRCA2 (2009) (57)
- Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells (2009) (56)
- Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. (2011) (55)
- A genome-wide association study of marginal zone lymphoma shows association to the HLA region (2015) (55)
- Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers (2006) (54)
- POSSIBLE RISK OF STEROID ADMINISTRATION IN PATIENTS AT RISK FOR AIDS (1985) (54)
- Prevalence of recurring BRCA mutations among Ashkenazi Jewish women with breast cancer. (1997) (54)
- BRCA mutation frequency and penetrance: new data, old debate. (2006) (54)
- Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (53)
- Molecular analysis of breaks in BCL-1 proto-oncogene in B-cell lymphomas with abnormalities of 11q13. (1989) (52)
- The signatures of autozygosity among patients with colorectal cancer. (2008) (51)
- Clusters of chromosome 9 aberrations are associated with clinico‐pathologic subsets of non‐Hodgkin's lymphoma (1993) (51)
- Risk of metachronous breast cancer after BRCA mutation–associated ovarian cancer (2013) (51)
- Cancer Susceptibility Mutations in Patients With Urothelial Malignancies. (2019) (51)
- Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers (2007) (50)
- Susceptibility Loci Associated with Specific and Shared Subtypes of Lymphoid Malignancies (2013) (49)
- Increased Progesterone Receptor Expression in Benign Epithelium of BRCA1-Related Breast Cancers (2004) (49)
- Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study (2020) (49)
- Immunohistochemical, molecular, and cytogenetic analysis of a consecutive series of 20 peripheral t‐cell lymphomas and lymphomas of uncertain lineage, including 12 Ki‐I positive lymphomas (1990) (48)
- Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. (2018) (48)
- Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors (2021) (47)
- Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers (2012) (47)
- Gene patents and personalized cancer care: impact of the Myriad case on clinical oncology. (2013) (47)
- Increased frequency of disease-causing MYH mutations in colon cancer families. (2006) (47)
- Oral Contraceptives and the Risk of Breast Cancer in BRCA 1 and BRCA 2 Mutation Carriers (2002) (47)
- Del (7)(q32) is associated with a subset of small lymphocytic lymphoma with plasmacytoid features. (1995) (47)
- t(3;22)(q27;q11): a novel translocation associated with diffuse non-Hodgkin's lymphoma. (1989) (46)
- Ki-1 antigen expression defines a favorable clinical subset of non-B cell non-Hodgkin's lymphoma. (1990) (46)
- Rare variants in XRCC2 as breast cancer susceptibility alleles (2012) (46)
- The role of prevention in oncology practice: results from a 2004 survey of American Society of Clinical Oncology members. (2006) (46)
- Description and pilot results from a novel method for evaluating return of incidental findings from next-generation sequencing technologies (2013) (46)
- Clinical validity assessment of genes frequently tested on hereditary breast and ovarian cancer susceptibility sequencing panels (2018) (45)
- A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. (2018) (45)
- Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci. (2015) (45)
- Time to check CHEK2 in families with breast cancer? (2008) (44)
- Rare variants of ATM and risk for Hodgkin's disease and radiation-associated breast cancers. (2002) (42)
- Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. (2016) (42)
- Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening (2020) (42)
- COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration (2013) (41)
- Reducing the risk of gynecologic cancer in the Lynch syndrome. (2006) (41)
- Genome-wide association studies of cancer predisposition. (2010) (41)
- The APC I1307K allele and breast cancer risk (1998) (41)
- Hereditary ovarian cancer in Ashkenazi Jews (2004) (41)
- Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). (2020) (40)
- Therapeutic Implications of Germline Testing in Patients With Advanced Cancers (2021) (40)
- Twenty‐one–gene recurrence score assay in BRCA‐associated versus sporadic breast cancers: Differences based on germline mutation status (2016) (40)
- Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women (2016) (39)
- A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. (2016) (39)
- Germline BRCA mutation does not prevent response to taxane‐based therapy for the treatment of castration‐resistant prostate cancer (2012) (39)
- The Genomics ADvISER: development and usability testing of a decision aid for the selection of incidental sequencing results (2018) (39)
- Genetic prognostic markers for colorectal cancer. (2000) (38)
- Genomic Biomarkers for Breast Cancer Risk. (2016) (38)
- The EGAPP initiative: lessons learned (2013) (37)
- Variants at IRX4 as prostate cancer expression quantitative trait loci (2013) (37)
- Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers (2015) (37)
- AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Consortium of Investigators of Modifiers of BRCA1/2 Study (2007) (37)
- Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping (2008) (36)
- Increased CpG methylation of the estrogen receptor gene in BRCA1-linked estrogen receptor-negative breast cancers (2002) (36)
- Rearrangements of the BCL 6 Gene in Diffuse Large Cell Non-Hodgkin ’ s Lymphoma (2000) (36)
- Prospective Feasibility Trial of a Novel Strategy of Facilitated Cascade Genetic Testing Using Telephone Counseling. (2019) (36)
- Evaluation of germline PTEN mutations in endometrial cancer patients. (2005) (36)
- A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers. (2021) (35)
- Ethical and legal aspects of cancer genetic testing. (2007) (35)
- Integrating somatic variant data and biomarkers for germline variant classification in cancer predisposition genes (2018) (35)
- The TP53 mutational spectrum and frequency of CHEK2*1100delC in Li–Fraumeni-like kindreds (2005) (35)
- Systematic immunohistochemistry screening for Lynch syndrome in early age-of-onset colorectal cancer patients undergoing surgical resection. (2012) (34)
- Small Non-Cleaved-Cell Lymphoma (Undifferentiated Lymphoma, Burkitt's Type) in American Adults: Results with Treatment Designed for Acute Lymphoblastic Leukemia (1991) (34)
- Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry. (2016) (33)
- Should all BRCA1 mutation carriers with stage I breast cancer receive chemotherapy? (2013) (33)
- Assessment of SLX4 Mutations in Hereditary Breast Cancers (2013) (33)
- Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. (2019) (33)
- Germline PALB2 mutation analysis in breast–pancreas cancer families (2011) (33)
- Clonal cytogenetic abnormalities in Hodgkin's disease (1991) (33)
- Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (32)
- Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk (2017) (32)
- Clonal hematopoiesis is associated with risk of severe Covid-19 (2020) (32)
- Ovarian carcinoma screening in women at intermediate risk (2005) (31)
- Recommendations from the EGAPP Working Group: does PCA3 testing for the diagnosis and management of prostate cancer improve patient health outcomes? (2013) (31)
- Risk of Endometrial Carcinoma Associated With BRCA Mutation (2001) (31)
- BCL6 gene rearrangement and other cytogenetic abnormalities in diffuse large cell lymphoma. (1995) (30)
- BRCA Mutations in Women with Ductal Carcinoma In situ (2007) (30)
- Incorporating information regarding preimplantation genetic diagnosis into discussions concerning testing and risk management for BRCA1/2 mutations (2012) (30)
- HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. (2018) (30)
- Candidate Genetic Modifiers for Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2014) (29)
- Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant (2009) (29)
- A636P is associated with early-onset colon cancer in Ashkenazi Jews. (2003) (29)
- Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA) (2009) (28)
- Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (28)
- Association of a HOXB13 variant with breast cancer. (2012) (27)
- The context-specific role of germline pathogenicity in tumorigenesis (2021) (27)
- The 6q22.33 Locus and Breast Cancer Susceptibility (2009) (27)
- Germline SDHA mutations in children and adults with cancer (2018) (26)
- The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study (2016) (26)
- Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses (2020) (26)
- Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. (2008) (26)
- Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers (2017) (25)
- Clonal hematopoiesis is associated with risk of severe Covid-19 (2021) (25)
- An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers (2015) (25)
- A counseling framework for moderate-penetrance colorectal cancer susceptibility genes (2018) (25)
- Genetic overlap between autoimmune diseases and non‐Hodgkin lymphoma subtypes (2019) (24)
- Analysis of Mismatch Repair Defects in the Familial Occurrence of Lymphoma and Colorectal Cancer (2002) (24)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types (2015) (24)
- Cytogenetic and molecular genetic analysis of abnormal cells in Hodgkin's disease. (1989) (24)
- Interest and Attitudes of Patients With Advanced Cancer With Regard to Secondary Germline Findings From Tumor Genomic Profiling. (2017) (24)
- Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects. (2020) (24)
- Clinical features and management of BRCA1 and BRCA2-associated prostate cancer. (2014) (23)
- BCL-6 in diffuse large-cell lymphomas. (1996) (23)
- Towards Automation of Germline Variant Curation in Clinical Cancer Genetics (2018) (23)
- Identification of germline genetic mutations in patients with pancreatic adenocarcinoma. (2013) (22)
- BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry (2019) (22)
- Genetic Variation in DNA Repair Pathways and Risk of Non-Hodgkin's Lymphoma (2014) (22)
- Oncologic therapy shapes the fitness landscape of clonal hematopoiesis (2019) (22)
- Breast cancer risk variants at 6 q 25 display different phenotype associations and regulate ESR 1 , RMND 1 and CCDC 170 (2016) (22)
- The future of clinical cancer genomics. (2016) (22)
- A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers (2012) (22)
- Genome-wide association studies of cancer: principles and potential utility. (2010) (22)
- The APCI1307K allele and breast cancer risk. (1998) (22)
- Evaluation of a decision aid for incidental genomic results, the Genomics ADvISER: protocol for a mixed methods randomised controlled trial (2018) (22)
- Determining the clinical validity of hereditary colorectal cancer and polyposis susceptibility genes using the Clinical Genome Resource Clinical Validity Framework (2018) (22)
- Unique de novo mutation of BRCA2 in a woman with early onset breast cancer (2002) (22)
- Genetic architectures of proximal and distal colorectal cancer are partly distinct (2020) (21)
- Uptake and acceptability of a mainstreaming model of hereditary cancer multigene panel testing among patients with ovarian, pancreatic, and prostate cancer (2021) (21)
- Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma (2020) (21)
- Rare de novo germline copy-number variation in testicular cancer. (2012) (21)
- Effectiveness of the Genomics ADvISER decision aid for the selection of secondary findings from genomic sequencing: a randomized clinical trial (2019) (21)
- Follicular lymphoma with t(8;14)(q24;q32): a distinct clinical and molecular subset of t(8;14)-bearing lymphomas. (1992) (21)
- The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (20)
- Ethical and legal implications of cancer genetic testing: do physicians have a duty to warn patients' relatives about possible genetic risks? (2008) (20)
- Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3 (2016) (20)
- Risks to Relatives in Genomic Research: A Duty to Warn? (2012) (20)
- Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma (2017) (19)
- Insurance reimbursement for risk-reducing mastectomy and oophorectomy in women with BRCA1 or BRCA2 mutations (2001) (19)
- Localization of breast cancer susceptibility loci by genome‐wide SNP linkage disequilibrium mapping (2006) (19)
- Decade in review—genomics: A decade of discovery in cancer genomics (2014) (19)
- Chromosome analysis in the management of patients with non-Hodgkin's lymphoma. (1992) (19)
- Differential recruitment of caspase 8 to cFlip confers sensitivity or resistance to Fas-mediated apoptosis in a subset of familial lymphoma patients. (2003) (19)
- EGFR mutant lung adenocarcinomas in patients with germline BRCA mutations. (2008) (19)
- Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers (2011) (19)
- Nonrandom chromosomal aberrations are associated with sites of tissue involvement in non-Hodgkin's lymphoma. (1989) (19)
- Heterozygous Mutations in DNA Repair Genes and Hereditary Breast Cancer: A Question of Power (2012) (19)
- Achieving universal genetic assessment for women with ovarian cancer: Are we there yet? A systematic review and meta-analysis. (2021) (19)
- Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma (2016) (18)
- Recommendations from the EGAPP Working Group: does genomic profiling to assess type 2 diabetes risk improve health outcomes? (2013) (18)
- Germline deletion of ETV6 in familial acute lymphoblastic leukemia. (2019) (18)
- No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. (2016) (18)
- A rapid and reliable test for BRCA1 and BRCA2 founder mutation analysis in paraffin tissue using pyrosequencing. (2009) (18)
- Patients' Medical and Psychosocial Experiences After Detection of a CDH1 Variant With Multigene Panel Testing. (2019) (18)
- Mendelian Randomization of Circulating Polyunsaturated Fatty Acids and Colorectal Cancer Risk (2020) (18)
- Absence of genomic BRCA1 and BRCA2 rearrangements in Ashkenazi breast and ovarian cancer families (2010) (18)
- Protein-altering germline mutations implicate novel genes related to lung cancer development (2020) (17)
- Inherited TP53 Variants and Risk of Prostate Cancer. (2021) (17)
- Germline mutations of AXIN2 are not associated with nonsyndromic colorectal cancer (2005) (17)
- Susceptibility loci associated with prostate cancer progression and mortality. (2010) (17)
- Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. (2018) (17)
- Inherited variants at 3q13.33 and 3p24.1 are associated with risk of diffuse large B-cell lymphoma and implicate immune pathways. (2019) (17)
- Small non-cleaved-cell lymphoma (undifferentiated lymphoma, Burkitt's type) in American adults: results with treatment designed for acute lymphoblastic leukemia. (1991) (17)
- Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (17)
- No major association between TGFBR1*6A and prostate cancer (2004) (17)
- Germline BRCA2 mutations detected in pediatric sequencing studies impact parents’ evaluation and care (2017) (17)
- Familial Adenomatous Polyposis and Mental Retardation Caused by a de novo Chromosomal Deletion at 5q15-q22: Report of a Case (2005) (17)
- Molecular structure of double reciprocal translocations: significance in B-cell lymphomagenesis. (1991) (16)
- Overexpression as a Marker of Poor Prognosis in Mantle Cell Lymphomas With t ( l 1 ; 14 ) ( q 13 ; q 32 ) (2002) (16)
- Development of Clinical Domain Working Groups for the Clinical Genome Resource (ClinGen): Lessons Learned and Plans for the Future (2018) (16)
- New BRCA2 mutation in an Ashkenazi Jewish family with breast and ovarian cancer (1997) (16)
- Tobacco control: reducing cancer incidence and saving lives. American Society of Clinical Oncology. (1996) (16)
- Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women (2011) (16)
- 11p15.5 epimutations in children with Wilms tumor and hepatoblastoma detected in peripheral blood (2020) (16)
- Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2mutation carriers (2012) (16)
- Transcriptome-wide association study of breast cancer risk by estrogen-receptor status (2020) (16)
- High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation (2018) (16)
- Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma (2020) (16)
- A family with three germline mutations in BRCAl and BRCA2 (1998) (16)
- Alterations of the BCL-6 gene in diffuse large-cell lymphoma. (1995) (15)
- Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome (2014) (15)
- A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (15)
- Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers (2019) (15)
- Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry (2012) (15)
- Localization of Cancer Susceptibility Genes by Genome-wide Single-Nucleotide Polymorphism Linkage-Disequilibrium Mapping (2004) (15)
- Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes. (2016) (15)
- BRCA1 R71K missense mutation contributes to cancer predisposition by increasing alternative transcript levels (2011) (15)
- An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality (2015) (15)
- Accuracy of BRCA1 and BRCA2 Founder Mutation Analysis in Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue (2006) (14)
- Breast Cancer Risk and 6q22.33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 (2012) (14)
- A case for expert curation: an overview of cancer curation in the Clinical Genome Resource (ClinGen) (2019) (14)
- Common Genetic Variants and Modification of Penetrance of BRCA 2-Associated Breast Cancer (2010) (14)
- Diagnosing hereditary colorectal cancer. (2010) (14)
- Cancer predisposing germline mutations in patients (pts) with urothelial cancer (UC) of the renal pelvis (R-P), ureter (U) and bladder (B). (2017) (13)
- Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes. (2021) (13)
- Psychosocial factors associated with the uptake of contralateral prophylactic mastectomy among BRCA1/2 mutation noncarriers with newly diagnosed breast cancer (2017) (13)
- Germline single nucleotide polymorphisms associated with response of urothelial carcinoma to platinum-based therapy: the role of the host. (2013) (13)
- Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer (2018) (13)
- Genome-wide analysis of the role of copy-number variation in pancreatic cancer risk (2013) (13)
- New pharmacogenomic paradigm in breast cancer treatment. (2010) (13)
- Breast cancer single-nucleotide polymorphisms: statistical significance and clinical utility. (2009) (13)
- Pan-cancer microsatellite instability to predict for presence of Lynch syndrome. (2018) (13)
- Familial Hodgkin's and non-Hodgkin's lymphoma: different patterns in first-degree relatives. (1997) (13)
- Characterization of a novel germline PALB2 duplication in a hereditary breast and ovarian cancer family (2016) (13)
- MSH6 mutations in hereditary nonpolyposis colon cancer: another slice of the pie. (2004) (12)
- Including Additional Controls from Public Databases Improves the Power of a Genome-Wide Association Study (2011) (12)
- Genetic architecture of prostate cancer in the Ashkenazi Jewish population (2011) (12)
- Participation in the cooperative family registry for breast cancer studies: issues of informed consent. (2000) (12)
- Educational and Psychosocial Support Needs in Lynch Syndrome: Implementation and Assessment of an Educational Workshop and Support Group (2017) (12)
- Utility of prospective pathologic evaluation to inform clinical genetic testing for hereditary leiomyomatosis and renal cell carcinoma (2017) (12)
- BRCA1 and BRCA2 Germline Mutations in Lymphoma Patients (2003) (11)
- Quality of life drives patients’ preferences for secondary findings from genomic sequencing (2020) (11)
- Prevalence of HOXB13 mutation in a population of Ashkenazi Jewish men treated for prostate cancer (2013) (11)
- The role of digital tools in the delivery of genomic medicine: enhancing patient-centered care (2021) (11)
- Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia (2018) (11)
- Inherited rare, deleterious variants in ATM increase lung adenocarcinoma risk (2020) (11)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (11)
- Multi-center prospective analysis of risk-reducing salpingo-oophorectomy to prevent BRCA-associated breast and ovarian cancer. (2006) (11)
- Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia (2020) (11)
- Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements (2015) (11)
- Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer (2020) (10)
- Genetic variants in germline TP53 and MDM2 SNP309 are not associated with early onset colorectal cancer (2008) (10)
- The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers (2012) (10)
- cDNA analysis demonstrates that the BRCA2 intronic variant IVS4-12del5 is a deleterious mutation. (2009) (10)
- Assessment of individuals with BRCA1 and BRCA2 large rearrangements in high-risk breast and ovarian cancer families (2014) (10)
- AURKA F 31 I Polymorphism and Breast Cancer Risk in BRCA 1 and BRCA 2 Mutation Carriers : A Consortium of Investigators of Modifiers of BRCA 1 / 2 Study (2007) (10)
- Familial acute myeloid leukemia and DiGuglielmo syndrome. (1995) (10)
- The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant (2021) (10)
- Four-year follow-up of outcomes following risk-reducing salpingo-oophorectomy in BRCA mutation carriers (2005) (10)
- The genetics of familial lymphomas (2004) (10)
- Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study. (2021) (10)
- Modeling genetic risk of breast cancer. (2007) (10)
- Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians (2019) (10)
- Assessment of the prevalence of de novo mutations in the BRCA1 and BRCA2 genes (2011) (9)
- Ethicolegal aspects of cancer genetics. (2010) (9)
- Ophira M. GinsburgCharmaine Kim-SingWilliam D. Foulkes • Parviz GhadirianHenry T. LynchPing SunSteven A. Narod • Hereditary Breast Cancer Clinical Study Group (2010) (9)
- Inherited predisposition to cancer: introduction and overview. (2010) (9)
- What Women with Breast Cancer Discuss with Clinicians About Risk for Their Adolescent Daughters (2012) (9)
- Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers (2016) (9)
- Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores (2021) (9)
- Cancer Causative Mutations Occurring in Early Embryogenesis. (2021) (9)
- The American society of clinical oncology position on genetic testing (1997) (9)
- Germline Variants Identified in Patients with Early-onset Renal Cell Carcinoma Referred for Germline Genetic Testing. (2021) (9)
- Benefits and Risks of Screening Mammography in Women With BRCA1 and BRCA2 Mutations-Reply (1997) (9)
- A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers (2020) (9)
- Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes (2019) (9)
- The BRCA1 Ashkenazi founder mutations occur on common haplotypes and are not highly correlated with anonymous single nucleotide polymorphisms likely to be used in genome-wide case-control association studies (2007) (9)
- Juvenile polyposis syndrome presenting with familial gastric cancer and massive gastric polyposis. (2012) (8)
- Genetic/familial high-risk assessment (2010) (8)
- Genetic Testing for Susceptibility to Cancer (1998) (8)
- Decision-Making Preferences About Secondary Germline Findings That Arise From Tumor Genomic Profiling Among Patients With Advanced Cancers. (2017) (8)
- Health outcomes, utility and costs of returning incidental results from genomic sequencing in a Canadian cancer population: protocol for a mixed-methods randomised controlled trial (2019) (8)
- Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer (2021) (8)
- Uptake of oophorectomy in women with findings on multigene panel testing: Results from the Prospective Registry of Multiplex Testing (PROMPT). (2020) (8)
- Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses (2021) (8)
- Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population (2021) (8)
- Genetic Factors: Hereditary Cancer Predisposition Syndromes (2014) (8)
- Prophylactic mastectomy in carriers of BRCA mutations. (2001) (8)
- Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (2022) (8)
- Prevalence of BRCA1 and BRCA2 mutations in Jewish women with triple negative breast cancer (2008) (7)
- Multigene Testing for Hereditary Cancer: When, Why, and How. (2017) (7)
- Illustrating Cancer Risk: Patient Risk Communication Preferences and Interest regarding a Novel BRCA1/2 Genetic Risk Modifier Test (2020) (7)
- Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant. (2016) (7)
- Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer. (2019) (7)
- Oophorectomy in carriers of BRCA mutations [3] (2002) (7)
- DNA-Repair Gene Mutations in Metastatic Prostate Cancer. (2016) (7)
- Single-amplicon MSH2 A636P Mutation Testing in Ashkenazi Jewish Patients With Colorectal Cancer: Role in Presurgical Management (2007) (7)
- Tumor relevant germline findings in targeted tumor sequencing using matched normal DNA of 1,570 unselected cases. (2015) (7)
- Outcome of Pancreatic Cancer Surveillance Among High-Risk Individuals Tested for Germline Mutations in BRCA1 and BRCA2 (2019) (6)
- A Single Nucleotide Polymorphism in the 5 Untranslated Region of RAD 51 and Risk of Cancer among BRCA 1 / 2 Mutation Carriers 1 (2001) (6)
- Discovery of common and rare genetic risk variants for colorectal cancer (2018) (6)
- Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (6)
- Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element (2021) (6)
- Monoclonal hypergammaglobulinemia without malignant transformation in angioimmunoblastic lymphadenopathy with dysproteinemia. (1986) (6)
- Consecutive lymphoma with monoclonal gammopathy in a married couple (1986) (6)
- Germline single-nucleotide polymorphisms (SNPs) associated with response of urothelial carcinoma (UC) to platinum-based therapy: The role of the host. (2011) (6)
- Genetic testing in gastrointestinal cancers: a case-based approach. (2012) (6)
- Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers (2012) (6)
- Common breast cancer risk loci predispose to distinct tumor subtypes (2019) (6)
- Cascade Testing for Hereditary Cancer Syndromes: Should We Move Toward Direct Relative Contact? A Systematic Review and Meta-Analysis (2022) (6)
- Comprehensive assessment of germline pathogenic variant detection in tumor-only sequencing (2022) (6)
- Factors Influencing Patient Preferences for Telehealth Cancer Genetic Counseling During the COVID-19 Pandemic (2021) (5)
- Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers. (2020) (5)
- Author Correction: Tumour lineage shapes BRCA-mediated phenotypes (2019) (5)
- Clinical Evaluation of Cisplatin Sensitivity of Germline Polymorphisms in Neoadjuvant Chemotherapy for Urothelial Cancer. (2016) (5)
- Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer (2010) (5)
- Prevalence of germline genetic alterations in colorectal cancer patients. (2018) (5)
- Benefits and risks of screening mammography in women with BRCA1 and BRCA2 mutations [4] (multiple letters) (1997) (5)
- Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk (2017) (4)
- Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (4)
- Funding for clinical (patient-oriented) oncology research: current status and recommendations for improvement. American Society of Clinical Oncology. (1996) (4)
- The 6 q 22 . 33 Locus and Breast Cancer Susceptibility (2009) (4)
- Incorporating progesterone receptor expression into the PREDICT breast prognostic model. (2022) (4)
- Toward automation of germline variant curation in clinical cancer genetics (2019) (4)
- DNA damage repair (DDR) germline mutations in patients (Pts) with urothelial carcinoma (UC). (2018) (4)
- 995 ANALYSIS OF STATIN MEDICATION, GENETIC VARIATION AND PROSTATE CANCER OUTCOMES (2011) (4)
- Paired Tumor-Normal Sequencing Provides Insights into TP53-Related Cancer Spectrum in Li-Fraumeni Patients. (2021) (4)
- Publisher Correction: Shared heritability and functional enrichment across six solid cancers (2019) (4)
- Genetic counseling issues (1997) (4)
- Comparison of up-front cash cards and checks as incentives for participation in a clinician survey: a study within a trial (2020) (4)
- Early results from the BRCA Founder Outreach (BFOR) Study: Population genetic screening using a medical model. (2019) (4)
- Facilitated cascade testing (FaCT): a randomized controlled trial (2020) (4)
- Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier (2013) (4)
- Collaborative science in the next-generation sequencing era: a viewpoint on how to combine exome sequencing data across sites to identify novel disease susceptibility genes (2016) (4)
- Prospective assessment for pathogenic germline alterations (PGA) in pancreas cancer (PAC). (2017) (4)
- Genetically Determined Height and Risk of Non-hodgkin Lymphoma (2020) (4)
- Multiple Primary Cancers in Patients Undergoing Tumor-Normal Sequencing Define Novel Associations (2021) (4)
- Variant t(8;14) translocations in non-Burkitt's non-Hodgkin's lymphomas. (1992) (4)
- 5Risk of developing uterine corpus cancer (Ut Ca) following risk-reducing salpingo-oophorectomy (RRSO) in women with BRCA mutations (2014) (3)
- PD10-05 OUTCOME OF GENETIC EVALUATION OF KIDNEY CANCER PATIENTS REFERRED FOR SUSPECTED HEREDITARY CANCER SYNDROMES (2014) (3)
- Abstract 3258: Preclinical evaluation of enhanced irofulven antitumor activity in an ERCC3 mutant background by in vitro and in vivo tumor models (2018) (3)
- Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients (2022) (3)
- Advances in Brief T b RI ( 6 A ) Is a Candidate Tumor Susceptibility Allele 1 (1999) (3)
- Adherence to mammogram (MMG) screening guidelines in BRCA1/2 mutation carriers (2005) (3)
- Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer (2022) (3)
- Altered tumor formation and evolutionary Altered tumor formation and evolutionnary selection of genetic variants in the human MDM4 oncogene (2009) (3)
- Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk (2020) (3)
- Mendelian randomisation study of smoking exposure in relation to breast cancer risk (2021) (3)
- Abstract LB-125: Germline mutations in BAP1 predispose to melanocytic nevi and melanoma (2011) (3)
- Gene-based Confirmatory Germline Testing Following Tumor-only Sequencing of Prostate Cancer. (2022) (3)
- Targeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study. (2021) (3)
- BRCA1: A new marker in the management of patients with breast cancer? (1996) (3)
- Are BRCA1- and BRCA2-associated breast cancers different? (2000) (3)
- Feasibility and yield of offering genetic counseling to all patients with newly diagnosed high-grade epithelial ovarian cancer. (2011) (3)
- Correction for Deco et al., Key role of coupling, delay, and noise in resting brain fluctuations (2009) (3)
- Case–control analysis identifies shared properties of rare germline variation in cancer predisposing genes (2019) (3)
- Disparities in cancer genetics care by race/ethnicity among pan‐cancer patients with pathogenic germline variants (2022) (3)
- Abstract 2598: Predicting breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers using polygenic risk scores (2016) (3)
- Molecular analysis of structural chromosome changes affecting chromosome band 11q23. (1989) (3)
- Association of germ-line variation with platinum-based chemotherapy response in patients (pts) with urothelial carcinoma (UC). (2011) (3)
- Prospective Registry of Multiplex Testing (PROMPT): Feasible and sustainable. (2018) (3)
- Erratum: Combined genetic assessment of transforming growth factor-β signaling pathway variants may predict breast cancer risk (Cancer Research (April 15, 2005) 65 (3454-3461)) (2006) (3)
- Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination (2021) (3)
- Targeted therapy based on germline analysis of tumor-normal sequencing (MSK-IMPACT) in a pan-cancer population. (2020) (3)
- Evaluating the association of multiple single nucleotide polymorphisms with response to gemcitabine and platinum combination chemotherapy in urothelial carcinoma of the bladder . (2017) (2)
- Feasibility of breast conserving treatment for breast cancer in women with germline BRCA mutations: A clinic-based series. (2004) (2)
- A prospective analysis of germline alterations (GA) in biliary tract cancer (BTC). (2017) (2)
- Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort. (2022) (2)
- Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis (2019) (2)
- Early age of onset and broad cancer spectrum persist in MSH6- and PMS2-associated Lynch syndrome. (2022) (2)
- Two truncating variants in FANCC and breast cancer risk (2019) (2)
- Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes (2022) (2)
- Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer. (2022) (2)
- Pathogenic Loss-of-Function Germline TERT Mutations in Patients With Solid Tumors (2019) (2)
- ARSENIC-ASSOCIATED ANGIOIMMUNOBLASTIC LYMPHADENOPATHY (1985) (2)
- Utility of ovarian cancer screening in women with BRCA mutations (2008) (2)
- MP30-12 RENAL CELL CARCINOMA AND NON-HODGKIN’S LYMPHOMA: GENOMIC APPROACHES TO IDENTIFICATION OF SHARED SUSCEPTIBILITY (2014) (2)
- Abstract 5071: A genome-wide association study suggests evidence of variants at 6p21.32 associated with marginal zone lymphoma (2014) (2)
- Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis (2020) (2)
- Pathogenicity of mutation analyzer (PathoMAN): A fast automation of germline genomic variant curation in clinical sequencing. (2017) (2)
- Case–control analysis identifies shared properties of rare germline variation in cancer predisposing genes (2018) (2)
- Response to Li and Hopper. (2021) (2)
- Breast cancer and BRCA1 mutations. (1996) (2)
- Frequency of actionable cancer predisposing germline mutations in patients with lung cancers. (2018) (2)
- Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study (2022) (2)
- Challenges and Opportunities in Engaging Primary Care Providers in BRCA Testing: Results from the BFOR Study (2021) (2)
- Disparities in pan-cancer patients undergoing germline cancer risk assessment by self-reported race/ethnicity and ancestry. (2021) (2)
- Expanded genetic testing of GIST patients identifies high proportion of non-syndromic patients with germline alterations (2023) (2)
- Detection of germline homologous recombination deficiency (HRD) in patients with metastatic esophagogastric (EG) cancer using clinical next generation sequencing (NGS). (2018) (2)
- Prevalence and clinical characterization of MMR-D/MSI extra-colonic cancers among germline PMS2 mutation carriers. (2020) (1)
- A Strategy for Large-Scale Systematic Pan-Cancer Germline Rare Variation Analysis (2017) (1)
- Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition (2022) (1)
- Characterization of patients with multiple primary tumors. (2020) (1)
- A case report of concurrent embryonal rhabdomyosarcoma and diffuse large B-cell lymphoma in an adult without identifiable cancer predisposition (2017) (1)
- The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk (2017) (1)
- Development of a novel measure of advanced cancer patients’ perceived utility of secondary germline findings from tumor genomic profiling (2023) (1)
- Selected abstracts submitted to the Third International Symposium on Hereditary Breast and Ovarian Cancer (2009) (1)
- Structural alterations of the BCL-6 gene in B cell lymphoma (1995) (1)
- Breast Cancer Risk Single Nucleotide Polymorphism (SNP) Genotypes Do Not Correlate with Risk Estimates from Existing Prediction Models. (2009) (1)
- The heritability of retinoblastoma: An institutional review. (2016) (1)
- Barriers to completion of cascade genetic testing: how can we improve the uptake of testing for hereditary breast and ovarian cancer syndrome? (2022) (1)
- Characterization of a germline splice site variant MLH1 c.678-3T>A in a Lynch syndrome family (2020) (1)
- Reply to R.L. Nussbaum et al and J.S. Dolinsky et al. (2017) (1)
- Characterization of findings on prostate cancer tumor sequencing that should prompt consideration for germline testing. (2021) (1)
- Prospective registry of multiplex testing (PROMPT): A web-based platform to assess cancer risk of genetic variants. (2016) (1)
- Uterine cancer (Ut Ca) following risk-reducing salpingo-oophorectomy (RRSO) in women with BRCA mutations (BRCA+): A multicenter, prospective study. (2015) (1)
- Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk (2020) (1)
- Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis (2020) (1)
- Prediction of pathologic complete response to neoadjuvant chemotherapy in urothelial cancer by genetic determinants of platinum sensitivity. (2013) (1)
- Prospective Registry of Multiplex Testing (PROMPT): Follow-up. (2019) (1)
- Impact of risk-reducing oophorectomy on quality of life in women at risk for ovarian cancer (2007) (1)
- Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 25 (10236-10241) DOI: 10.1073/pnas. 0901298106) (2009) (1)
- Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in $\small \textit{BRCA1}$ and $\small \textit{BRCA2}$ Mutation Carriers (2016) (1)
- Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer (2018) (1)
- University of Groningen Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA 1 and BRCA 2 Mutation Carriers (2017) (1)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (1)
- Abstract 1291: High and moderate penetrance germline mutations in a number of genes are responsible for a small proportion of familial breast cancer risk in BRCAx families (2014) (1)
- Characterization of rectal cancer in patients with Lynch syndrome. (2013) (1)
- Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (1)
- CHEK2 Alleles Predispose to Renal Cancer in Poland-In Reply. (2019) (1)
- Discovery and prevalence of cancer-susceptibility germline mutations (Mts) in patients (Pts) with advanced renal cell carcinoma (aRCC). (2017) (1)
- Early age of onset and broad cancer spectrum persist in MSH6 and PMS2-associated Lynch syndrome. (2021) (1)
- Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women (2016) (1)
- The BRCA founder outreach study: Initial results of a digital health model. (2020) (1)
- Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers (2022) (1)
- SNPs at SMG7 associated with time from biochemical recurrence to prostate cancer death. (2022) (1)
- COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration (2013) (1)
- Clinical evaluation of cisplatin sensitivity germ line polymorphisms in neoadjuvant chemotherapy (NAC) for urothelial cancer (UC). (2014) (1)
- Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (1)
- A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos (2022) (1)
- Regulation of Laboratory-Developed Tests in Preventive Oncology: Emerging Needs and Opportunities. (2022) (1)
- High-depth whole genome sequencing of a large population-specific reference panel: Enhancing sensitivity, accuracy, and imputation (2017) (1)
- Association of single-nucleotide polymorphisms in BCL2L1 and TACC3 with response to bacillus Calmette-Guérin intravesical therapy in non-muscle-invasive bladder cancer. (2012) (1)
- Reversion mutations in germline BRCA1/2-mutant tumors reveal a BRCA-mediated phenotype in non-canonical histologies (2022) (1)
- Cancer Risks in BRCA1 and BRCA2 Mutation Carriers (2007) (1)
- Genetic Predictors for Fecal Propionate and Butyrate-Producing Microbiome Pathway are Not Associated with Colorectal Cancer Risk: A Mendelian Randomization Analysis. (2022) (1)
- A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis (2016) (1)
- Does postmenopausal risk-reducing salpingo-oophorectomy reduce the risk of BRCA-associated breast cancer? (2013) (1)
- Breast Cancer Risk and 6 q 22 . 33 : Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA 1 / 2 (2012) (1)
- Germline alterations in cancer susceptibility genes in women with high-risk bladder cancer: Implications for germline testing and clinical management. (2021) (1)
- Cancer susceptibility mutations in individuals with breast and ovarian cancer using next-generation sequencing. (2016) (1)
- Abstract 1122: Germline mutation prevalence in young adults with cancer (2020) (1)
- Genetic testing for susceptibility to cancer. Task Force on Cancer Genetics Education. (1998) (1)
- Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (1)
- MP61-05 PILOT INVESTIGATION OF VARIANTS IN DNA REPAIR PATHWAYS AND ASSOCIATION WITH RESPONSE TO PLATINUM-BASED CHEMOTHERAPY IN BLADDER CANCER. (2014) (0)
- Abstract 5214: Expanding the spectrum of germline-driven cancers by leveraging population-scale targeted tumor and normal sequencing (2023) (0)
- Determining the clinical validity of hereditary colorectal cancer and polyposis susceptibility genes using the Clinical Genome Resource Clinical Validity Framework (2018) (0)
- Male breast cancer in BRCA1 and BRCA2 mutation carriers (2018) (0)
- Examining patients’ medical and psychosocial experiences following detection of a CDH1 variant with multiplex genetic testing. (2018) (0)
- Identification of the nonsense SLX4 variant and evaluation of pathogenicity of the SLX4 variants by complementation assay. (2013) (0)
- Colorectal Cancer The Signatures of Autozygosity among Patients with Updated (2008) (0)
- large cell lymphoma REL proto-oncogene is frequently amplified in extranodal diffuse (2013) (0)
- Large-Scale Linkage Analysis of Multiple Myeloma (MM) and Monoclonal Gammopathy of Undetermined Significance (MGUS) Families (2018) (0)
- Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (0)
- Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia (2018) (0)
- Genetic Factors (2020) (0)
- Breast cancer risks in individuals testing negative for known family mutations in BRCA1 or BRCA2. (2016) (0)
- Somatic tumor profiling of DNA mismatch repair deficient (MMR-D) colorectal cancers (CRC). (2016) (0)
- Genomic Profiles for Disease Risk (2017) (0)
- Genetic Risks for Breast Cancer in African American Women: Analysis of Candidate Single Nucleotide Polymorphisms from Association Studies. (2009) (0)
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2020) (0)
- Needs assessment and utilization of an educational workshop and support group for Lynch syndrome patients. (2013) (0)
- Abstract LB-304: Oncologic therapy for solid tumors alters the risk of clonal hematopoiesis (2019) (0)
- The association between Polygenic Risk Scores and contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: Analyses in the CIMBA consortium (2018) (0)
- A counseling framework for moderate-penetrance colorectal cancer susceptibility genes (2018) (0)
- NCCN Genetic/Familial High-Risk Assessment: Breast Panel Members Genetic/Familial High-Risk Assessment: Breast (2002) (0)
- Germline drivers of gynecologic carcinosarcomas (2023) (0)
- Abstract 2600:SLX4mutation in hereditary breast cancer (2012) (0)
- Abstract 1752: BRCA-mediated tumorigenesis is origin and cell-type dependent (2019) (0)
- Abstract 796: ERCC3 R109X is a moderate risk breast cancer risk variant in Ashkenazi Jews (2016) (0)
- Tumour lineage shapes BRCA-mediated phenotypes (2019) (0)
- Characterization of a germline splice site variant MLH1 c.678-3T>A in a Lynch syndrome family (2020) (0)
- Germline Mutations of the Ataxia-Telangiectasia Gene, ATM, as a Risk Factor for Radiation-Associated Breast Cancer (1999) (0)
- Abstract 4280: FH (rs367543046, chr1:241661227 A/ATTT) heterozygous carrier status does not confer risk to hereditary leiomyomatosis and renal cell cancer (HLRCC) and prostate cancer (2017) (0)
- Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients (2022) (0)
- KLHDC8B Is a Novel, Mitotically-Regulated Classical Hodgkin’s Lymphoma Candidate Susceptibility Gene. (2006) (0)
- Genome-Wide Association Study for Waldenström Macroglobulinemia Identifies Novel Susceptibility Loci (2017) (0)
- Clinical validity assessment of genes frequently tested on hereditary breast and ovarian cancer susceptibility sequencing panels (2018) (0)
- Clinical characterization of DNA mismatch repair deficiency (MMR-D) in endometrial cancer (EC). (2016) (0)
- Abstract 3282: Determination of cancer susceptibility in probands with breast and ovarian cancer (2014) (0)
- O017/#479 Germline pathogenic variants in DNA repair genes and endometrial cancer risk (2022) (0)
- Genetic testing experiences and emotional reactions among individuals with variant of uncertain significance results from cancer multiplex genetic testing. (2020) (0)
- Abstract SS01-01: Using genomic technologies to improve cancer risk assessment (2011) (0)
- Abstract 5220: Evaluation of ACMG guideline classified variants in 180 cancer and incidental non-cancer genes in families with breast/ovarian cancer (2016) (0)
- Variable penetrance of CDH1 mutation diffuse gastric cancer: A genomic analysis. (2013) (0)
- Abstract P2-11-21: Integration of an ancestrally unbiased polygenic risk score with the Tyrer-Cuzick breast cancer risk model (2022) (0)
- Utilization of clinical genetic counseling among childhood and young adult cancer survivors in a registry trial (2020) (0)
- Protein-altering germline mutations implicate novel genes related to lung cancer development (2020) (0)
- Fallopian T ube a nd P rimary P eritoneal C arcinomas A ssociated With BRCA Mutations (2003) (0)
- 566 IDENTIFICATION OF GENETIC MARKERS ASSOCIATED WITH RESPONSE TO BACILLUS CALMETTE-GUÉRIN INTRAVESICAL THERAPY IN NON-MUSCLE-INVASIVE BLADDER CANCER (2012) (0)
- Association of personal and family history with decision to undergo risk-reducing salpingo-oophorectomy in BRCA mutation carriers (2005) (0)
- Abstract 826: Large-scale genome-wide association study identifies multiple novel germline susceptibility variants associated with bladder cancer risk (2021) (0)
- Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier (2012) (0)
- Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions. (2023) (0)
- Book Review: Genetic Predisposition to Cancer (2004) (0)
- Association of breast cancer risk in BRCA 1 and BRCA 2 mutation carriers with genetic variants showing differential allelic expression (2016) (0)
- TITLE: Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk (2020) (0)
- Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriers (2022) (0)
- Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome (2014) (0)
- Book Review Hereditary Gynecologic Cancer: Risk, Prevention and Management Edited by Karen H. Lu. 285 pp., illustrated. New York, Informa Healthcare, 2008. $199.95. 978-1-4200-5287-9 (2009) (0)
- Variant t(8;14) translocations in non-Burkitt9s non-Hodgkin9s lymphomas [letter; comment] (1992) (0)
- Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 (2016) (0)
- Effectiveness of the Genomics ADvISER decision aid for the selection of secondary findings from genomic sequencing: a randomized clinical trial (2019) (0)
- Ductal carcinoma in situ and BRCA mutations: Association and risk factors. (2006) (0)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- TP53 and CHEK2 *1100delC gene mutation in North American families suggestive Li-Fraumeni syndrome: Memorial Sloan-Kettering experience. (2004) (0)
- Abstract 729: Zygosity, lineage, and penetrance dictate the role of germline pathogenicity in tumorigenesis (2019) (0)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- PD12-09 INHERITED CANCER PREDISPOSITION GENE VARIANTS IN PATIENTS WITH NON-MUSCLE INVASIVE BLADDER CANCER (2020) (0)
- Identification of genetic test results with conflicting interpretations in prospective registry of multiplex testing (PROMPT). (2016) (0)
- Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers (2014) (0)
- Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination (2021) (0)
- Single nucleotide polymorphisms as markers of bacillus Calmette-Guérin intravesical therapy response in non-muscle invasive bladder cancer. (2012) (0)
- Evaluation of germline genetic testing criteria in early-onset kidney cancer. (2021) (0)
- Use of genome-wide scan in women with breast cancer to identify common germline variants that may be associated with recurrence. (2009) (0)
- Tumor testing in men with prostate cancer to predict for germline DNA-damage repair mutations. (2019) (0)
- Quality of life drives patients’ preferences for secondary findings from genomic sequencing (2020) (0)
- Apoptosis defects in familial lymphoma patients (2000) (0)
- Prevalence of HOXB13 mutation in a population of Ashkenazi Jewish men treated for prostate cancer (2013) (0)
- Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2020) (0)
- Couch Care and Prevention Setting Paradigms in Personalized Cancer BRCA : Two Decades After (2014) (0)
- What happens in the long term: Uptake of cancer surveillance and prevention strategies among at‐risk relatives with pathogenic variants detected via cascade testing (2022) (0)
- Multi gene panel testing in unselected patients (pts) with endometrial cancer (EC). (2017) (0)
- Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (0)
- Risk of breast cancer (BC) after BRCA-mutation associated ovarian cancer (BRCA-OC): Memorial Sloan-Kettering Cancer Center (MSKCC) experience. (2011) (0)
- P-060: Pathogenic germline mutations in a large cohort of multiple myeloma (2022) (0)
- Association of germ-line single nucleotide polymorphisms (SNPs) with pathologic response to neoadjuvant cisplatin-based chemotherapy in patients with resectable non-small cell lung cancers. (2013) (0)
- PD43-07 CLINICAL CHARACTERISTICS ASSOCIATED WITH HIGH-RISK CANCER-PREDISPOSITION GERMLINE MUTATIONS IN PATIENTS WITH UROTHELIAL CARCINOMA: IMPLICATIONS FOR GENETIC TESTING (2021) (0)
- Abstract 2685: Identification of circulating protein biomarkers for colorectal cancer risk: A genetic instrument analysis (2019) (0)
- Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2. (2023) (0)
- Polymorphisms of the TGF-β pathway and breast cancer risk: A case control study. (2004) (0)
- BIOLOGY Correction for ‘ ‘ Dissection of the high rate constant for the binding of a ribotoxin to the ribosome (2009) (0)
- Characterization of colorectal cancer (CRC) in Lynch syndrome (LS) patients with MSH6 or PMS2 mutations. (2013) (0)
- Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (0)
- Comprehensive Analysis of Germline Drivers in Endometrial Cancer. (2023) (0)
- 43. Association between Clonal Hematopoiesis and Inherited Cancer Susceptibility Genes (2022) (0)
- Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes (2021) (0)
- Feasibility and long-term utility of a psychosocial support group for patients with Lynch syndrome. (2016) (0)
- Counseling and Testing for Inherited Predisposition to Cancer (2017) (0)
- Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing (2017) (0)
- Evaluation of the potential clinical utility of risk models incorporating genomic risk information. (2010) (0)
- Decision Making about Contralateral Prophylactic Mastectomy Among BRCA1/2 Noncarriers with Newly-diagnosed Breast Cancer: Examining Cognitive, Emotional, and Sociodemographic Influences (2015) (0)
- BRCA haploinsufficiency in human breast tumorigenesis (2005) (0)
- Presence of additional cytogenetic aberrations predict a worse outcome in diffuse large B-cell lymphoma with bcl-6 rearrangement (1996) (0)
- Correction: Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers (2018) (0)
- Commentary (Offit): Genetics of Colorectal Cancer (2006) (0)
- Abstract LB-070: Next generation sequencing of prostate cancer reveals germline and somatic alterations detected at diagnosis and at metastasis that may impact clinical decision making (2016) (0)
- Abstract PD14-05: PD14-05 Prospective longitudinal validation of a breast cancer risk prediction model in a cohort of 130,058 women (2023) (0)
- Abstract 1281: Germline mutations inNBNconferring DNA damage response defects are found in patients with multiple cancer types (2017) (0)
- Determination of cancer susceptibility in probands with breast and ovarian cancer (2014) (0)
- Abstract 2742: Potential burden of germline findings in targeted tumor sequencing using matched normal DNA (2015) (0)
- Saliva samples for genomic testing for preventive oncology: Improving the yield. (2013) (0)
- UICC International Union Against Cancer Familial Cancer and Prevention (2000) (0)
- Abstract 2182: Ancestry inference and population-specific disparities in a real-world clinical sequencing cohort (2022) (0)
- Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (2023) (0)
- 915 EXOME SEQUENCING OF EXTREME PHENOTYPES TO IDENTIFY VARIANTS PREDICTIVE OF RESPONSE TO CHEMOTHERAPY IN BLADDER CANCER (2013) (0)
- TGFBR1 *6A a nd C ancer R isk: A M eta-Analysis o f S even C ase-Control S tudies (2003) (0)
- BRCA Mutations in Womenwith Ductal Carcinoma In situ (2007) (0)
- Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry (2012) (0)
- Comprar Genetic Predisposition To Cancer, An Issue Of Hematology/Oncology Clinics Of North America, Vol. 24-5 | Kenneth Offit | 9781437722048 | Saunders (2010) (0)
- Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes (2021) (0)
- Somatic tumor profiling of DNA mismatch repair (MMR) deficient endometrial cancers (EC). (2017) (0)
- Adherence to hereditary non-polyposis colorectal cancer (HNPCC) screening guidelines (2008) (0)
- A validation of models for prediction of pathogenic variants in mismatch repair genes. (2022) (0)
- Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival (2023) (0)
- Association of single-nucleotide polymorphisms in BCL2L1 and TACC3 with response to bacillus Calmette-Guérin intravesical therapy in non-muscle-invasive bladder cancer. (2012) (0)
- High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation (2018) (0)
- Correction for Atwal et al., Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene (2009) (0)
- The Genomics ADvISER: development and usability testing of a decision aid for the selection of incidental sequencing results (2018) (0)
- SNP rs2180341 per-allele hazard ratios (HRs) and 95% confidence intervals (CIs) among Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) in A. BRCA1 mutation carriers B. BRCA2 mutation carriers. (2012) (0)
- MP36-06 UTILITY OF PROSPECTIVE PATHOLOGIC EVALUATION TO INFORM CLINICAL GENETIC TESTING FOR HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CARCINOMA (2014) (0)
- Topic: AS07-Singular Entities/Subtypes/AS07a-ARCH, CCUS, ICUS: RARE GENETIC DETERMINANTS OF CLONAL HEMATOPOIESIS AND PROGRESSION TO HEMATOLOGIC MALIGNANCIES (2023) (0)
- P063: Prospective longitudinal validation of a breast cancer risk prediction model in a cohort of 130,058 individuals* (2023) (0)
- Abstract A45: Novel SUFU splice mutation in a child with multiple tumors (2016) (0)
- Great expectations: patients’ preferences for clinically significant results from genomic sequencing (2023) (0)
- Germline alterations in cancer susceptibility genes in women with high-risk bladder cancer: implications for germline testing and clinical management (2021) (0)
- Book Review Multiple Primary Cancers Edited by Alfred I. Neugut, Anna T. Meadows, and Eliezer Robinson. 484 pp., illustrated. Baltimore, Lippincott Williams & Wilkins, 1999. $110. 0-683-30124-1 (2000) (0)
- An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers (2015) (0)
- Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (2019) (0)
- Development of patient “profiles” to tailor counseling for incidental genomic sequencing results (2019) (0)
- Shared heritability and functional enrichment across six solid cancers (2019) (0)
- Development of Clinical Domain Working Groups for the Clinical Genome Resource (ClinGen): lessons learned and plans for the future (2018) (0)
- A randomized study of cash cards versus checks as clinician survey incentives (2020) (0)
- Author Correction: Tumour lineage shapes BRCA-mediated phenotypes (2019) (0)
- Exome sequencing of extreme phenotypes to identify variants predictive of response to chemotherapy in bladder cancer. (2013) (0)
- Oncotype DX in BRCA-associated vs. sporadic breast cancers: Differences based on germline mutation status and potential implications for adjuvant systemic therapy (AST). (2015) (0)
- A case report of concurrent embryonal rhabdomyosarcoma and diffuse large B-cell lymphoma in an adult without identifiable cancer predisposition (2017) (0)
- Mendelian randomization study of age at menarche and age at 1 menopause and the risk of colorectal cancer (2018) (0)
- PD44-01 WHEN SHOULD PROSTATE CANCER TUMOR SEQUENCING PROMPT CONSIDERATION FOR GERMLINE TESTING? (2021) (0)
- Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry (2023) (0)
- Cancer risks in women from BRCA-negative hereditary breast and ovarian cancer families (2013) (0)
- Impact of bilateral oophorectomy on contralateral breast cancer risk in BRCA negative women from site-specific hereditary breast cancer kindreds. (2013) (0)
- q 31 . 2 and in ZNF 365 are associated with breast cancer risk for BRCA 1 and / or BRCA 2 mutation carriers (2012) (0)
- Breast cancer risk prediction using the novel germ-line signatures in epigenome regulatory pathways. (2013) (0)
- Abstract 2033: Germline mutations inETV6confer risk of thrombocytopenia and acute lymphocytic leukemia (2015) (0)
- MP6-16 GERMLINE VARIANTS WITHIN THE PTEN/PI3K AXIS AND ASSOCIATION WITH CASTRATE RESISTANT PROSTATE CANCER AND PROSTATE CANCER SPECIFIC MORTALITY (2015) (0)
- Abstract 5092: Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma (2011) (0)
- Prevalence of BRCA1 and BRCA2 founder mutations in Ashkenazi Jewish (AJ) families with breast cancer (BC) and pancreatic cancer (PC) (2005) (0)
- Abstract 5703: Oncologic therapy shapes the fitness landscape of clonal hematopoiesis (2020) (0)
- Genomics and Cancer Prevention (2013) (0)
- Genome sequencing of multiple primary tumors to reveal underlying germline cancer susceptibility. (2013) (0)
- University of Groningen DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers Osorio, (2014) (0)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk (2017) (0)
- Abstract P6-09-01: RAD51B loss-of-function variants confer susceptibility to hereditary breast and ovarian cancers and result in tumors with genomic features of homologous recombination repair defects (2020) (0)
- Abstract 2378: Harmonization of next generation sequencing data within consortia for gene discovery in familial breast cancer (2014) (0)
- Genitourinary Cancers Other than Prostate Cancer in a BRCA-tested Cohort from a Single Institution. (2015) (0)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Survival benefit for BRCA-associated epithelial ovarian cancer (OC) is not explained by primary platinum sensitivity alone (2008) (0)
- Abstract LB-A07: Targeting nucleotide excision repair defects in cancer (2019) (0)
- Microsatellite Instability Testing in Genetically Heterogeneous Populations (2006) (0)
- Breast cancer risk with hormone replacement after risk-reducing salpingo-oophorectomy in BRCA mutation carriers: Does it abrogate the benefit? (2014) (0)
- Prospective agnostic germline testing in pediatric cancer patients. (2020) (0)
- Abstract 4265: Risks of familial breast cancer associated with known and proposed breast cancer susceptibility genes (2017) (0)
- Abstract P2-09-24: Information preferences and short-term psychological responses to multiplex genetic testing among individuals at risk for hereditary breast cancer (2016) (0)
- Incidence of ovarian cancer in BRCA-negative hereditary breast cancer families. (2004) (0)
- Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers (2017) (0)
- 453 THE ASSOCIATION OF GENITOURINARY CANCERS WITH BRCA CARRIER STATUS IN A CLINICALLY TESTED COHORT FROM A SINGLE INSTITUTION (2013) (0)
- Defining hereditary upper tract urothelial carcinoma: Implications for genetic testing and clinical management. (2022) (0)
- Abstract LB-383: Towards automation of germline variant curation in cancer genetics (2018) (0)
- Protection from late-occurring anthracycline-related cardiotoxicity among childhood cancer survivors with a RARG coding variant. (2017) (0)
- Abstract 5367: Ngago: no evidence of targeted endonuclease activity (2017) (0)
- Transcriptional regulation and prostate cancer risk loci. (2013) (0)
- Risk of new breast and ovarian cancers and utility of incremental genetic testing in a high-risk BRCA negative cohort (2018) (0)
- Breast Cancer Genetics: Impact on the Jewish Woman and Her Family (2004) (0)
- Pilot investigation of variants in DNA repair pathways and association with response to platinum-based chemotherapy in bladder cancer. (2014) (0)
- A breast cancer (BC) risk model incorporating Tyrer-Cuzick version 8 (TCv8) and a polygenic risk score (PRS) for diverse ancestries. (2022) (0)
- The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (0)
- Abstract 4158: Dissecting the role of zygosity and lineage in Lynch Syndrome-associated microsatellite Instability (2019) (0)
- Genetic predisposition to cancer. Preface. (2010) (0)
- Association of rs12662670 with breast cancer in Asian ER (2012) (0)
- Targeted next-generation sequencing (NGS) of germline DNA to identify genetic predisposition to gastric cancer (GC) in patients with CDH1-mutation negative early-onset (EO) or familial GC (FGC). (2018) (0)
- Overlap of lymphoma risk SNPs with regulatory regions in GM12878. (2015) (0)
- Papillary mucinous adenomaarising in adenomyomatous hyperplasia ofthegall bladder (1995) (0)
- Adherence to extracolonic cancer screening in Lynch syndrome kindreds. (2009) (0)
- NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects (2022) (0)
- Identification of a new breast cacner risk locus in a genome-wide association study of Ashkenazi Jews (2008) (0)
- Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma (2023) (0)
- Characterization of Rectal Cancer in Patients With Lynch Syndrome (2015) (0)
- Molecular Oncology: Genome-wide association studies of cancer predisposition (2013) (0)
- Commentary (Offit): Evaluation and Management of Women With BRCA1/2 Mutations (2005) (0)
- Title Interplay between BRCA 1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer (2012) (0)
- Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (0)
- Correction: Toward automation of germline variant curation in clinical cancer genetics (2019) (0)
- Considerations in genetic counseling for inherited breast cancer predisposition. (2002) (0)
- Early-onset renal cell carcinoma: assessment of germline genetic testing criteria (2021) (0)
- Inherited mutations in breast cancer patients with and without multiple primary cancers. (2018) (0)
- Higher Than Expected Carrier Frequency Of The Dyskeratosis Congenita RTEL1 p.Arg1264His recessive Founder In Individuals Of Ashkenazi Jewish Ancestry (2013) (0)
- Correction: Toward automation of germline variant curation in clinical cancer genetics (2019) (0)
- Clonal Hematopoiesis and COVID-19 Severity in Cancer Patients (2020) (0)
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Other Resources About Kenneth Offit
What Schools Are Affiliated With Kenneth Offit?
Kenneth Offit is affiliated with the following schools:
- Institute of Cancer Research
- Autonomous University of Barcelona
- Icahn School of Medicine at Mount Sinai
- Princeton University
- Cornell University
- Lund University
- University of Toronto
- Pomeranian Medical University in Szczecin
- Columbia University
- University of Cambridge
- Leiden University
- Seoul National University
