Kenneth Roux
American scientist
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Chemistry
Kenneth Roux's Degrees
- PhD Chemistry University of California, Berkeley
- Masters Chemical Engineering Stanford University
Why Is Kenneth Roux Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kenneth Roux is an American academic biologist whose research addresses structural analysis of the AIDS viruses HIV-1 and SIV, and the antibodies that neutralize them, as well as food-allergen characterization and immunoassay development. He is the Kurt G. Hofer Professor of Biological Science at Florida State University , where he is affiliated with the Institute of Molecular Biophysics. He has been a member of FSU's biological science faculty since 1978. Roux received his B.S. degree from Delaware Valley College in 1970 and then attended Tulane University, from which he received his M.S. in 1972 and his Ph.D. in 1974.
Kenneth Roux's Published Works
Published Works
- Distribution and three-dimensional structure of AIDS virus envelope spikes (2006) (763)
- Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition (2003) (745)
- An improved smaller biotin ligase for BioID proximity labeling (2016) (482)
- High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR. (1996) (417)
- Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions (2003) (393)
- Nature of Nonfunctional Envelope Proteins on the Surface of Human Immunodeficiency Virus Type 1 (2006) (349)
- Flexibility of human IgG subclasses. (1997) (226)
- Optimization and troubleshooting in PCR. (1995) (217)
- Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular convergence of NAR and unusual mammalian immunoglobulins. (1998) (214)
- Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip. (2014) (209)
- Effects of food processing on the stability of food allergens. (2005) (194)
- Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under six years of age (2008) (165)
- Oligomeric and Conformational Properties of a Proteolytically Mature, Disulfide-Stabilized Human Immunodeficiency Virus Type 1 gp140 Envelope Glycoprotein (2002) (161)
- Ana o 1, a cashew (Anacardium occidental) allergen of the vicilin seed storage protein family. (2002) (160)
- Purification, Characterization, and Immunogenicity of a Soluble Trimeric Envelope Protein Containing a Partial Deletion of the V2 Loop Derived from SF162, an R5-Tropic Human Immunodeficiency Virus Type 1 Isolate (2003) (156)
- Structure and specificity of lamprey monoclonal antibodies (2008) (142)
- Optimization and troubleshooting in PCR. (2009) (141)
- A view of the human idiotypic repertoire. Electron microscopic and immunologic analyses of spontaneous idiotype-anti-idiotype dimers in pooled human IgG. (1990) (137)
- Tree Nut Allergens (2003) (132)
- A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120. (2007) (131)
- Ana o 3, an important cashew nut (Anacardium occidentale L.) allergen of the 2S albumin family. (2005) (121)
- Biochemical characterization of amandin, the major storage protein in almond (Prunus dulcis L.). (2002) (121)
- Tomographic subvolume alignment and subvolume classification applied to myosin V and SIV envelope spikes. (2009) (120)
- Ana o 2, a Major Cashew (Anacardium occidentale L.) Nut Allergen of the Legumin Family (2003) (116)
- AIDS virus envelope spike structure. (2007) (112)
- Epitope mapping of a 95 kDa antigen in complex with antibody by solution-phase amide backbone hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron resonance mass spectrometry. (2011) (110)
- Detection and stability of the major almond allergen in foods. (2001) (107)
- On the structure of polymeric IgM (1988) (106)
- Impact of γ‐irradiation and thermal processing on the antigenicity of almond, cashew nut and walnut proteins (2004) (105)
- Identification and Characterization of an Arginine Kinase as a Major Allergen from Silkworm (Bombyx mori) Larvae (2009) (102)
- Cryoelectron Tomography of HIV-1 Envelope Spikes: Further Evidence for Tripod-Like Legs (2008) (95)
- Linear IgE epitope mapping of the English walnut (Juglans regia) major food allergen, Jug r 1. (2002) (92)
- Effects of roasting, blanching, autoclaving, and microwave heating on antigenicity of almond (Prunus dulcis L.) proteins. (2002) (92)
- Comparisons of the ability of human IgG3 hinge mutants, IgM, IgE, and IgA2, to form small immune complexes: a role for flexibility and geometry. (1998) (91)
- Pistachio vicilin, Pis v 3, is immunoglobulin E‐reactive and cross‐reacts with the homologous cashew allergen, Ana o 1 (2008) (87)
- Soluble Mimetics of Human Immunodeficiency Virus Type 1 Viral Spikes Produced by Replacement of the Native Trimerization Domain with aHeterologous Trimerization Motif: Characterization and Ligand Binding Analysis (2005) (78)
- Characterization of the soluble allergenic proteins of cashew nut (Anacardium occidentale L.). (2002) (77)
- Effect of high pressure processing on the immunoreactivity of almond milk (2014) (77)
- Immunoglobulin Structure and Function as Revealed by Electron Microscopy (1999) (75)
- Using mismatched primer-template pairs in touchdown PCR. (1994) (68)
- Cloning and characterization of profilin (Pru du 4), a cross-reactive almond (Prunus dulcis) allergen. (2006) (66)
- Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1. (2009) (66)
- Solubilization and electrophoretic characterization of select edible nut seed proteins. (2009) (65)
- Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop (2010) (63)
- Conformational epitope mapping of Pru du 6, a major allergen from almond nut. (2013) (61)
- Production and characterization of rabbit polyclonal antibodies to almond (Prunus dulcis L.) major storage protein. (1999) (59)
- Probing functional sites on complement protein B with monoclonal antibodies. Evidence for C3b-binding sites on Ba. (1987) (56)
- Effects of processing on immunoreactivity of cashew nut (Anacardium occidentale L.) seed flour proteins. (2008) (55)
- Electrophoretic and immunological analyses of almond (Prunusdulcis l.) genotypes and hybrids. (2001) (52)
- Effects of processing and storage on walnut (Juglans regia L) tannins (2001) (50)
- Functional properties of select edible oilseed proteins. (2010) (50)
- Tree nut allergy (2003) (48)
- DNA Vaccine that Targets Hemagglutinin to MHC Class II Molecules Rapidly Induces Antibody-Mediated Protection against Influenza (2013) (48)
- Linear IgE-epitope mapping and comparative structural homology modeling of hazelnut and English walnut 11S globulins. (2009) (48)
- Differential Segmental Flexibility and Reach Dictate the Antigen Binding Mode of Chimeric IgD and IgM: Implications for the Function of the B Cell Receptor1 (2004) (48)
- Localization of the phosphocholine-binding sites on C-reactive protein by immunoelectron microscopy. (1983) (47)
- Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. (2008) (47)
- A sensitive sandwich ELISA for the detection of trace amounts of cashew (Anacardium occidentale L.) nut in foods. (2003) (47)
- Biochemical composition and immunological comparison of select pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars. (2007) (46)
- Advances in Seed Protein Research: A Perspective on Seed Allergens (2006) (46)
- Anti-IgM-mediated B cell signaling. Molecular analysis of ligand binding requisites for human B cell clonal expansion and tolerance (1988) (44)
- A strategy for single site PCR amplification of dsDNA: priming digested cloned or genomic DNA from an anchor-modified restriction site and a short internal sequence. (1990) (42)
- Antigenic stability of pecan [Carya illinoinensis (Wangenh.) K. Koch] proteins: effects of thermal treatments and in vitro digestion. (2006) (42)
- Immunoelectron microscopic localization of idiotypes and allotypes on immunoglobulin molecules. (1982) (41)
- Cloning, Expression and Patient IgE Reactivity of Recombinant Pru du 6, an 11S Globulin from Almond (2011) (40)
- Structural Flexibility and Functional Valence of CD4-IgG2 (PRO 542): Potential for Cross-Linking Human Immunodeficiency Virus Type 1 Envelope Spikes (2001) (39)
- A sensitive and robust competitive enzyme-linked immunosorbent assay for Brazil nut ( Bertholletia excelsa L.) detection. (2009) (37)
- Cloning and characterization of an 11S legumin, Car i 4, a major allergen in pecan. (2011) (37)
- IgE epitope proximity determines immune complex shape and effector cell activation capacity (2015) (37)
- Effect of food matrix on amandin, almond (Prunus dulcis L.) major protein, immunorecognition and recovery (2010) (36)
- One-step optimization using touchdown and stepdown PCR. (1997) (35)
- Origin of octameric creatine kinases (1998) (35)
- Production and analysis of recombinant tree nut allergens. (2014) (34)
- Idiotypic–anti‐idiotypic complexes and their in vivo metabolism (2002) (34)
- Effect of food matrix and processing on release of almond protein during simulated digestion (2014) (34)
- Latent a1 VH germline genes in an a2a2 rabbit. Evidence for gene conversion at both the germline and somatic levels. (1991) (33)
- Cloning and characterization of 2S albumin, Car i 1, a major allergen in pecan. (2011) (33)
- Characterization of a cashew allergen, 11S globulin (Ana o 2), conformational epitope. (2010) (31)
- Immunoelectron microscopy of idiotype-anti-idiotype complexes. (1989) (28)
- Purified, proteolytically mature HIV type 1 SOSIP gp140 envelope trimers. (2007) (26)
- Construction of an extended three-dimensional idiotope map by electron microscopic analysis of idiotope-anti-idiotope complexes. (1987) (26)
- Do anemonefishes use molecular mimicry to avoid being stung by host anemones (1994) (26)
- A molecular model of type I allergy: identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcepsilonRI interaction and reacts with receptor-bound IgE. (2001) (26)
- cDNA Cloning, expression and characterization of an allergenic 60s ribosomal protein of almond (prunus dulcis). (2009) (25)
- Mapping of a conformational epitope on the cashew allergen Ana o 2: a discontinuous large subunit epitope dependent upon homologous or heterologous small subunit association. (2010) (25)
- Direct demonstration of multiple VH allotopes on rabbit Ig molecules: allotope characteristics and Fab arm rotational flexibility revealed by immunoelectron microscopy (1984) (24)
- Binding of Anti-Membrane-Proximal gp41 Monoclonal Antibodies to CD4-Liganded and -Unliganded Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Virions (2011) (23)
- Critical and direct involvement of the CD23 stalk region in IgE binding (2016) (23)
- Purification and biochemical characterization of Brazil nut (Bertholletia excelsa L.) seed storage proteins. (2010) (22)
- Recombination activating genes-1 and -2 of the rabbit: cloning and characterization of germline and expressed genes. (1993) (22)
- Biochemical characterization of soluble proteins in pecan [Carya illinoinensis (Wangenh.) K. Koch]. (2008) (22)
- A 50 kDa Maize γ-Zein Has Marked Cross-Reactivity with the Almond Major Protein (2005) (21)
- Rapid Screening for Potential Epitopes Reactive with a Polycolonal Antibody by Solution-Phase H/D Exchange Monitored by FT-ICR Mass Spectrometry (2013) (21)
- A fourth heavy chain variable region subgroup, w, with 2 variants defined by an induced auto-antiserum in the rabbit. (1981) (20)
- Biochemical and spectroscopic characterization of almond and cashew nut seed 11S legumins, amandin and anacardein. (2011) (20)
- Dynamic gene interactions in the evolution of rabbit VH genes: a four codon duplication and block homologies provide evidence for intergenic exchange. (1985) (20)
- A murine monoclonal antibody based enzyme-linked immunosorbent assay for almond (Prunus dulcis L.) detection. (2013) (19)
- Monitoring the formation of soluble immune complexes composed of idiotype and anti-idiotype antibodies by electron microscopy. (1994) (18)
- Electron microscopic and immunochemical analysis of the broadly neutralizing HIV-1-specific, anti-carbohydrate antibody, 2G12. (2004) (18)
- Epitope mapping of 7S cashew antigen in complex with antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry. (2015) (17)
- Trimolecular Complex Formation of IgE, FcεRI, and a Recombinant Nonanaphylactic Single-Chain Antibody Fragment with High Affinity for IgE 1 (2009) (16)
- Variation in the ordered structure of complexes between CD154 and anti-CD154 monoclonal antibodies. (2002) (16)
- Heteroduplex cleavage analysis using S1 nuclease. (1999) (15)
- Effects of processing and storage on almond (Prunus dulcis L.) amandin immunoreactivity. (2017) (15)
- Effects of the Maillard Reaction on the Immunoreactivity of Amandin in Food Matrices. (2017) (14)
- A predominant idiotype on rabbit anti-VH a1 allotype antibodies: sharing by both major and minor VH subgroups. (1982) (13)
- Identification and cloning of Jug r 4, a major food allergen from english walnut belonging to the legumin group* (2003) (12)
- Cross-reactivity of human IgG anti-F(ab')2 antibody with DNA and other nuclear antigens. (1997) (12)
- Parameters influencing measurement of the Gag antigen-specific T-proliferative response to HIV type 1 infection. (2000) (11)
- 424 Cross-reactivity of walnut and other tree nuts by IgE immunoblot inhibition (2000) (11)
- Enzyme-linked immunosorbent assay (ELISA) for detection of sulfur-rich protein (SRP) in soybeans (Glycine max L.) and certain other edible plant seeds. (2008) (11)
- Single-step PCR optimization using touchdown and stepdown PCR programming. (2002) (11)
- Cross-reactivity of walnut, cashew, and hazelnut legumin proteins in tree nut allergic patients (2004) (10)
- Cross-reactive idiotypes on heterologous anti-allotype antibody. (1984) (9)
- Murine IgE and IgG antibody responses to allergenic and non-allergenic foods: Potential model for allergenicity assessment of foods in man (2004) (9)
- Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5 (2017) (9)
- Auto-antibody to an Ig VH region allotype: induction of anti-a1 antibody in an a1-suppressed a1a2 heterozygous rabbit. (1977) (9)
- Application of mouse monoclonal antibody (mAb) 4C10-based enzyme-linked immunosorbent assay (ELISA) for amandin detection in almond (Prunus dulcis L.) genotypes and hybrids (2015) (8)
- Visualization of Retroviral Envelope Spikes in Complex with the V3 Loop Antibody 447-52D on Intact Viruses by Cryo-Electron Tomography (2014) (8)
- Suppression and enhancement of the rabbit primary in vitro antibody response with anti-allotype antibody: concurrent effects on thymidine incorporation, blastogenesis, and cell surface Ig. (1979) (8)
- Comparison of Laboratory-Developed and Commercial Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assays for Almond (Prunus dulcis) Detection and Quantification. (2017) (7)
- The identification of a VH subgroup allotypic specificity, y30, which differentiates the y33 allele into two variants. Implications for rabbit VH gene organization and evolution. (1981) (7)
- Rabbit latent allotypes: Current status and future directions (1983) (7)
- Identification of a common Ara h 3 epitope recognized by both the capture and the detection monoclonal antibodies in an ELISA detection kit (2017) (6)
- Immunoglobulin E-reactive proteins in cashew (Anacardium occidentale) apple juice concentrate. (2008) (6)
- Expression of histocompatibility loci in the leopard frog. (1974) (6)
- A Cherry Seed-Derived Spice, Mahleb, is Recognized by Anti-Almond Antibodies Including Almond-Allergic Patient IgE. (2017) (5)
- Effects of long-term frozen storage on electrophoretic patterns, immunoreactivity, and pepsin in vitro digestibility of soybean (Glycine max L.) proteins. (2009) (5)
- Comparison of latent and nominal rabbit Ig VHa1 allotype cDNA sequences. (1988) (5)
- IgE-reactive 60S Ribosomal Protein P2 in Almond (Prunus Dulcis) and Walnut (Juglans Regia), a New Class of Food Allergen Cross-reactive with Fungal Aeroallergens (2007) (5)
- Characterization of biosynthetic IgG oligomers resulting from light chain variable domain duplication. (1994) (5)
- A 50 kDa maize gamma-zein has marked cross-reactivity with the almond major protein. (2005) (5)
- Induced latent allotypes within rabbit anti‐crossreactive idiotype reagents. Direct immunoelectron microscopic evidence (1984) (5)
- Evidence for a major histocompatibility complex in the leopard frog (1975) (5)
- Ana o 2, a major cashew nut allergen of the legumin family (2003) (4)
- IgE-Reactive Proteins in Cashew Apple Juice Concentrate are Removed by Filtration (2006) (3)
- Idiotypic specificities which arise naturally in rabbits following allotype suppression of the major VH subgroup (1980) (3)
- Effect of phenolics on amandin immunoreactivity (2018) (3)
- Monoclonal antibodies specific for the b5 allotype of rabbit kappa light chains. (1983) (3)
- High and Low Annealing Temperatures Increase Both Specificity and Yield in Touchdown and (2009) (3)
- Ana o 3, an important cashew nut allergen of the 2S albumin family (2004) (3)
- Pecan (Carya illinoinensis) detection using a monoclonal antibody-based direct sandwich enzyme-linked immunosorbent assay (2019) (3)
- A reevaluation of rabbit anti-allotype antibody for the presence of cross-reactive idiotypes. I. A species-specific idiotype on rabbit anti-a1 antibody is recognized by guinea pig anti-IdX antibody. (1985) (2)
- Ana o 1, a major cashew nut allergen of the vicilin family (2002) (2)
- Identification of allergenic cross-reactive proteins in cashew and pistachio nut (2005) (2)
- An increase in the number of recombinant molecules and other effects of the simultaneous allotype suppression of trans-chromosomal a VH and n Cmu Ig gene products. (1982) (2)
- A reevaluation of rabbit anti-allotype antibody for the presence of cross-reactive idiotypes. II. Expression of rabbit a1-like images on goat antibody after immunization with anti-a1 antibody. (1985) (2)
- A sensitive sandwich ELISA for the detection of trace amount of cashew nut in foods (2002) (2)
- Characterization of additional rabbit IgM allotypes and the effect of suppression of a VH locus allotypes on the expression of n C mu locus allotypes. (1982) (2)
- Sa.18Pistachio Vicilin, Pis v 1, is Allergenic and Cross-reactive with the Homologous Cashew Allergen, Ana o 1 (2007) (2)
- 437 An immunoassay for the detection of almond in foods (2000) (2)
- The glutelin fraction of walnut kernels (juglans regia) contains unique allergens not visible in the salt soluble fraction (2002) (1)
- Rabbit RAG-2 UTRs: characterization of an unusually large 3′ untranslated region (1997) (1)
- Comparative Tryptic Peptide Analysis Of Rabbit Heavy Chain Allotypes By Hplc (1985) (1)
- Mouse monoclonal antibody bearing a VH framework region determinant similar to a rabbit VHa1 allotope. (1987) (1)
- Response of the rabbit VH subgroups a and y following antigenic stimulation. (1983) (1)
- IGE AND IGG ANTIBODY RESPONSES TO WALNUT AND CASHEW ALLERGENS IN ORALLY IMMUNIZED MICE. - FP10 (2004) (1)
- Structured object representation of biomolecular images for two-dimensional shape discrimination via feedforward networks (1994) (1)
- Identification of profilin as an almond nut allergen (2005) (1)
- Serologic and biochemical analysis of latent a1 IgG. (1986) (0)
- Idiotypic-antiidiotypic interaction patterns and in vivo metabolism of immune complexes at immunotargeting (2000) (0)
- InfluenzaAntibody-Mediated Protection against MHC Class II Molecules Rapidly Induces DNA Vaccine that Targets Hemagglutinin to (2013) (0)
- ELECTRON TOMOGRAPHY OF MACROMOLECULAR ASSEMBLIES (2007) (0)
- Function of the B Cell Receptor Chimeric IgD and IgM: Implications for the Dictate the Antigen Binding Mode of Differential Segmental Flexibility and Reach (2004) (0)
- An Electron Microscopic View of the Geometry and Dynamics of Idiotype–Anti-Idiotype Interactions (1997) (0)
- Tomographic Subvolume Averaging and Subvolume Classification of SIV Envelope Spike Motifs (2008) (0)
- Tomographyon Intact Viruses by Cryo-Electron in Complex with the V3 Loop Antibody Visualization of Retroviral Envelope Spikes (2014) (0)
- One-Step Optimization Using Touchdown and Stepdown Polymerase Chain Reaction (2000) (0)
- Cryoelectron Tomography Shows 3D Structure of Surface Spikes (2006) (0)
- BIOCHEMICAL AND IMMUNOCHEMICAL PROPERTIES OF AMANDIN (2002) (0)
- Cell Receptor Implications for the Function of the B Mode of Chimeric IgD and IgM: Reach Dictate the Antigen Binding Differential Segmental Flexibility and (2010) (0)
- High Affinity for IgE with Single-Chain Antibody Fragment Recombinant Nonanaphylactic IgE, Fc{epsilon}RI, and a Trimolecular Complex Formation of (2010) (0)
- Subject Index Vol. 131, 2003 (2003) (0)
- Affinity for IgE Single-Chain Antibody Fragment with High RI, and a Recombinant Nonanaphylactic e Trimolecular Complex Formation of IgE, Fc (0)
- Domestic rabbits and wild Australian rabbits display similar variable heavy-chain haplotypes. (1982) (0)
- IMMUNOELECTRON MICROSCOPIC ANALYSIS OF THE IMMUNOGLOBULIN MOLECULE FOR IDIOTYPES AND ALLOTYPES (1982) (0)
- Contents Vol. 131, 2003 (2003) (0)
- Characterisation of recombinant CD23 in the trimeric complex with IgE and allergen (2015) (0)
- Segmentation by Classification: A Novel and Reliable Approach for Semi-Automatic Selection of HIV/SIV Envelope Spikes. (2019) (0)
- Flexibility and Geometry Small Immune Complexes: A Role for Hinge Mutants, IgM, IgE, and IgA2, to Form Comparisons of the Ability of Human IgG3 (1998) (0)
- Nucleic Acids Research Dynamic gene interactions in the evolution of rabbit VH genes: a four codon duplication and block bomologles provide evidence for intergenk exchange (2005) (0)
- Regulation of rabbit immunoglobulins. Introductory remarks (1983) (0)
- An accurate and reliable method for automatic picking of HIV/SIV spikes (2011) (0)
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