Kenneth W. Kinzler

Kenneth W. Kinzler's AcademicInfluence.com Rankings

Kenneth W. Kinzler

Philosophy

#1650

World Rank

#2957

Historical Rank

Logic

#267

World Rank

#553

Historical Rank

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Philosophy

Why Is Kenneth W. Kinzler Influential?

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According to Wikipedia, Kenneth Wayne Kinzler is a professor of oncology, and director of the Ludwig Center at Johns Hopkins University at the Sidney Kimmel Comprehensive Cancer Center. Kinzler received his PhD from Johns Hopkins University in 1988. He is of German descent.

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Kenneth W. Kinzler's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

WAF1, a potential mediator of p53 tumor suppression (1993) (8623)
Cancer Genome Landscapes (2013) (6203)
Lessons from Hereditary Colorectal Cancer (1996) (5073)
Identification of c-MYC as a target of the APC pathway. (1998) (4868)
An Integrated Genomic Analysis of Human Glioblastoma Multiforme (2008) (4366)
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade (2017) (4313)
Cancer genes and the pathways they control (2004) (4247)
Genetic instabilities in human cancers (1998) (4217)
Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses (2008) (3758)
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. (2015) (3718)
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies (2014) (3526)
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma (1997) (3456)
High Frequency of Mutations of the PIK3CA Gene in Human Cancers (2004) (3428)
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC (1997) (3376)
Requirement for p53 and p21 to sustain G2 arrest after DNA damage. (1998) (2974)
The Consensus Coding Sequences of Human Breast and Colorectal Cancers (2006) (2878)
A simplified system for generating recombinant adenoviruses. (1998) (2702)
The Genomic Landscapes of Human Breast and Colorectal Cancers (2007) (2549)
A model for p53-induced apoptosis (1997) (2531)
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. (1995) (2466)
Identification of FAP locus genes from chromosome 5q21. (1991) (2379)
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer (1993) (2347)
Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer (2010) (2299)
Serial Analysis of Gene Expression (1995) (2145)
Amplification of a gene encoding a p53-associated protein in human sarcomas (1992) (2074)
Definition of a consensus binding site for p53 (1992) (2053)
APC mutations occur early during colorectal tumorigenesis (1992) (2025)
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. (1998) (2005)
Genetic instability in colorectal cancers (1997) (1997)
p53 function and dysfunction (1992) (1955)
The multistep nature of cancer. (1993) (1925)
Genes expressed in human tumor endothelium. (2000) (1839)
Identification of a chromosome 18q gene that is altered in colorectal cancers. (1990) (1771)
Circulating mutant DNA to assess tumor dynamics (2008) (1754)
Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 (2011) (1652)
Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer (1994) (1620)
Mutations of mitotic checkpoint genes in human cancers (1998) (1562)
Detection and localization of surgically resectable cancers with a multi-analyte blood test (2018) (1556)
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers (2012) (1550)
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 (1993) (1530)
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors (2011) (1474)
Digital PCR. (1999) (1441)
PUMA induces the rapid apoptosis of colorectal cancer cells. (2001) (1328)
Association of the APC tumor suppressor protein with catenins. (1993) (1299)
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status (2002) (1288)
p21 is necessary for the p53-mediated G1 arrest in human cancer cells. (1995) (1278)
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells (2002) (1259)
Erratum: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene (1992) (1255)
14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression (1997) (1160)
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal (2013) (1148)
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. (1995) (1140)
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma (2010) (1123)
The Genetic Basis of Human Cancer (1997) (1106)
Disruption of p53 in human cancer cells alters the responses to therapeutic agents. (1999) (1103)
Detection and quantification of mutations in the plasma of patients with colorectal tumors. (2005) (1076)
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. (2015) (1068)
Hypermutability and mismatch repair deficiency in RER+ tumor cells (1993) (1060)
Identification of p53 as a sequence-specific DNA-binding protein (1991) (1055)
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs (1999) (1044)
The colorectal microRNAome. (2006) (999)
Detection and quantification of rare mutations with massively parallel sequencing (2011) (992)
Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients (1996) (975)
Mutational Analysis of the APC/β-Catenin/Tcf Pathway in Colorectal Cancer (1998) (944)
Role of BAX in the apoptotic response to anticancer agents. (2000) (924)
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer (2016) (922)
Gene expression profiles in normal and cancer cells. (1997) (901)
Altered Telomeres in Tumors with ATRX and DAXX Mutations (2011) (894)
14-3-3σ is required to prevent mitotic catastrophe after DNA damage (1999) (878)
Mutant PIK3CA promotes cell growth and invasion of human cancer cells. (2005) (867)
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. (1987) (862)
Gatekeepers and caretakers (1997) (853)
Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells (2009) (848)
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability (1995) (845)
Somatic mutations of the mitochondrial genome in human colorectal tumours (1998) (841)
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 (1996) (817)
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system (2007) (803)
Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations (2003) (798)
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. (1995) (794)
Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene (2009) (788)
Genetic instability and darwinian selection in tumours. (1999) (785)
Analysis of human transcriptomes (1999) (783)
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. (1991) (772)
Comparative lesion sequencing provides insights into tumor evolution (2008) (771)
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. (1992) (741)
Accumulation of driver and passenger mutations during tumor progression (2009) (734)
Allelic loss of chromosome 18q and prognosis in colorectal cancer. (1994) (729)
The Genetic Landscape of the Childhood Cancer Medulloblastoma (2011) (711)
Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development (2011) (711)
Identification of an amplified, highly expressed gene in a human glioma. (1987) (703)
Cancer risk associated with germline DNA mismatch repair gene mutations. (1997) (702)
Characterization of the Yeast Transcriptome (1997) (699)
Human Smad3 and Smad4 are sequence-specific transcription activators. (1998) (687)
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC (1997) (686)
A Phosphatase Associated with Metastasis of Colorectal Cancer (2001) (656)
Using the transcriptome to annotate the genome (2002) (645)
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers (1996) (632)
Scrambled exons (1991) (622)
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. (1998) (619)
Cancer-susceptibility genes. Gatekeepers and caretakers. (1997) (609)
PUMA mediates the apoptotic response to p53 in colorectal cancer cells (2003) (598)
Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. (2012) (592)
Allelic Variation in Human Gene Expression (2002) (591)
14-3-3sigma is a p53-regulated inhibitor of G2/M progression. (1997) (579)
Colorectal cancer: Mutations in a signalling pathway (2005) (578)
Inactivation of hCDC4 can cause chromosomal instability (2004) (568)
Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing (2012) (568)
p53 Mutation and MDM2 amplification in human soft tissue sarcomas. (1993) (563)
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas (2013) (555)
Molecular determinants of dysplasia in colorectal lesions. (1994) (554)
Landscaping the Cancer Terrain (1998) (553)
Apoptosis and APC in colorectal tumorigenesis. (1996) (544)
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways (2011) (535)
Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers (2004) (533)
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas (2012) (532)
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. (1992) (529)
The Antisense Transcriptomes of Human Cells (2008) (526)
Contribution of bone marrow–derived endothelial cells to human tumor vasculature (2005) (519)
Combinatorial chemoprevention of intestinal neoplasia (2000) (518)
APC binds to the novel protein EB1. (1995) (516)
The GLI gene encodes a nuclear protein which binds specific sequences in the human genome (1990) (509)
Mutations of GTBP in genetically unstable cells. (1995) (508)
Oncogenic forms of p53 inhibit p53-regulated gene expression (1992) (505)
Genetic determinants of p53-induced apoptosis and growth arrest. (1996) (502)
Heteroplasmic mitochondrial DNA mutations in normal and tumor cells (2010) (501)
Microbiota organization is a distinct feature of proximal colorectal cancers (2014) (496)
Identification of CDK4 as a target of c-MYC. (2000) (495)
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway (2012) (492)
Combination bacteriolytic therapy for the treatment of experimental tumors (2001) (490)
A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. (1995) (489)
Identification and classification of p53-regulated genes. (1999) (484)
CpG methylation is maintained in human cancer cells lacking DNMT1 (2000) (484)
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. (1998) (479)
Oncogenic forms of p53 inhibit p53-regulated gene expression. (1992) (477)
Deletion of p16 and p15 genes in brain tumors. (1994) (464)
Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells (2014) (461)
Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer. (2015) (461)
A public database for gene expression in human cancers. (1999) (447)
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers. (1999) (446)
The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations (2007) (442)
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. (2003) (436)
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. (2001) (431)
BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions (2006) (429)
ATM mutations in patients with hereditary pancreatic cancer. (2012) (427)
Cell surface tumor endothelial markers are conserved in mice and humans. (2001) (426)
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome (2011) (425)
Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. (2009) (425)
Sequence-specific transcriptional activation is essential for growth suppression by p53. (1994) (423)
DNA methylation and genetic instability in colorectal cancer cells. (1997) (423)
Cell-cycle arrest versus cell death in cancer therapy (1997) (420)
Addressing overdiagnosis and overtreatment in cancer: a prescription for change. (2014) (414)
Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing (2010) (410)
Genetic Progression and the Waiting Time to Cancer (2007) (408)
Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma (2011) (405)
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers (2008) (403)
Corrections and Clarifications: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene (1992) (403)
The GLI gene is a member of the Kruppel family of zinc finger proteins (1988) (401)
Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma (2011) (400)
Epitope landscape in breast and colorectal cancer. (2008) (396)
Molecular diagnosis of familial adenomatous polyposis. (1993) (396)
Top-down morphogenesis of colorectal tumors (2001) (393)
Securin Is Required for Chromosomal Stability in Human Cells (2001) (389)
Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers (2017) (387)
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma (2012) (379)
Cancer‐Associated Mutations in Endometriosis without Cancer (2017) (375)
APC mutations in colorectal tumors with mismatch repair deficiency. (1996) (364)
Tumour suppression: Disruption of HAUSP gene stabilizes p53 (2004) (364)
Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer (2014) (361)
Wild-type but not mutant APC associates with the microtubule cytoskeleton. (1994) (360)
Detecting colorectal cancer in stool with the use of multiple genetic targets. (2001) (347)
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. (1999) (345)
Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. (2012) (344)
Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas (2015) (343)
Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells (2001) (340)
A combination of molecular markers and clinical features improve the classification of pancreatic cysts. (2015) (339)
Detection of APC mutations in fecal DNA from patients with colorectal tumors. (2002) (337)
Founding mutations and Alu-mediated recombination in hereditary colon cancer (1995) (334)
Mutational analysis of the tyrosine kinome in colorectal cancers. (2003) (330)
SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer (2009) (329)
Frequency of Smad gene mutations in human cancers. (1997) (326)
Mismatch repair deficiency in phenotypically normal human cells (1995) (322)
Sensitive digital quantification of DNA methylation in clinical samples (2009) (319)
The GLI-Kruppel family of human genes (1988) (319)
Somatic mutations of EGFR in colorectal cancers and glioblastomas. (2004) (315)
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53 (2009) (304)
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers (2008) (300)
Inactivation of both APC alleles in human and mouse tumors. (1994) (299)
Prediction of germline mutations and cancer risk in the Lynch syndrome. (2006) (293)
Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord (2015) (290)
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. (1999) (290)
Small changes in expression affect predisposition to tumorigenesis (2002) (288)
Evaluating the evaluation of cancer driver genes (2016) (285)
Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. (2012) (283)
Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer. (2019) (282)
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer (2017) (281)
Cooperative effects of genes controlling the G(2)/M checkpoint. (2000) (280)
Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types (2011) (278)
Conversion of diploidy to haploidy (2000) (274)
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses (2014) (270)
Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers (2013) (269)
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer. (2016) (261)
The Path to Cancer --Three Strikes and You're Out. (2015) (261)
Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers (2004) (260)
Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer (1992) (259)
Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention (2020) (257)
A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane (2009) (255)
BEAMing up for detection and quantification of rare sequence variants (2006) (251)
Bacteriolytic therapy can generate a potent immune response against experimental tumors. (2004) (250)
Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells (2001) (250)
MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. (2003) (249)
Expression of the APC tumor suppressor protein in oligodendroglia (1996) (241)
Mechanisms underlying losses of heterozygosity in human colorectal cancers (2001) (231)
The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. (2007) (229)
Allelotype of pancreatic adenocarcinoma. (1994) (228)
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. (1995) (225)
Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing (2013) (224)
Characterization of MAD2B and other mitotic spindle checkpoint genes. (1999) (224)
Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics. (2007) (224)
Association between wild type and mutant APC gene products. (1993) (219)
Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors (2014) (218)
Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients. (2008) (217)
Characterization of human FAST-1, a TGFβ and activin signal transducer (1998) (216)
Amplification of cyclin genes in colorectal carcinomas. (1993) (215)
Mad-related genes in the human (1996) (214)
The Predictive Capacity of Personal Genome Sequencing (2012) (213)
Analysing uncharted transcriptomes with SAGE. (2000) (212)
TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine. (2013) (212)
Life (and death) in a malignant tumour (1996) (210)
Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome. (1998) (209)
PRL-3 expression in metastatic cancers. (2003) (209)
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. (2004) (208)
Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study (2018) (207)
Three classes of genes mutated in colorectal cancers with chromosomal instability. (2004) (207)
Paradoxical inhibition of solid tumor cell growth by bcl2. (1994) (207)
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS. (2013) (204)
The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia? (2014) (201)
GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity (1990) (201)
Targeted inactivation of p53 in human cells does not result in aneuploidy. (2002) (200)
Minimal functional driver gene heterogeneity among untreated metastases (2018) (198)
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients. (2004) (198)
The DCC gene product in cellular differentiation and colorectal tumorigenesis. (1994) (197)
Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T (2007) (192)
Low‐grade serous carcinomas of the ovary contain very few point mutations (2012) (191)
Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers (2003) (188)
p53 tagged sites from human genomic DNA. (1994) (186)
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers. (2016) (186)
Sulindac suppresses tumorigenesis in the Min mouse. (1996) (185)
Prevalence of somatic alterations in the colorectal cancer cell genome (2002) (185)
Carcinogen-specific induction of genetic instability (2001) (184)
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses. (2004) (183)
Carcinogens leave fingerprints (1992) (181)
Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma. (1986) (173)
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. (1998) (173)
Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome (2018) (173)
Secreted and cell surface genes expressed in benign and malignant colorectal tumors. (2001) (172)
Molecular genetic profiles of colitis-associated neoplasms. (1994) (171)
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer (2016) (166)
Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues. (1996) (166)
Counting alleles to predict recurrence of early-stage colorectal cancers (2002) (165)
Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins. (1989) (162)
Use of isogenic human cancer cells for high-throughput screening and drug discovery (2001) (160)
Detection of proximal colorectal cancers through analysis of faecal DNA (2002) (156)
Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas (2013) (156)
Serial assessment of human tumor burdens in mice by the analysis of circulating DNA. (2007) (155)
Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing (2016) (154)
TEM8 Interacts with the Cleaved C5 Domain of Collagen α3(VI) (2004) (154)
Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers (2018) (154)
Mutant p53 proteins bind DNA abnormally in vitro. (1991) (153)
Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria (2003) (150)
A multidimensional analysis of genes mutated in breast and colorectal cancers. (2007) (148)
A Bacterial Protein Enhances the Release and Efficacy of Liposomal Cancer Drugs (2006) (144)
Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors. (2006) (144)
The role of companion diagnostics in the development and use of mutation-targeted cancer therapies (2006) (141)
Common occurrence of APC and K-ras gene mutations in the spectrum of colitis-associated neoplasias. (1995) (139)
Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers (2021) (138)
Whole‐exome sequencing of pancreatic neoplasms with acinar differentiation (2014) (138)
Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. (1996) (136)
The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. (2000) (136)
The role of hPMS1 and hPMS2 in predisposing to colorectal cancer. (2001) (135)
Targeting a neoantigen derived from a common TP53 mutation (2021) (134)
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers (2009) (130)
Polymerase δ variants in RER colorectal tumours (1995) (130)
Relationship between gene amplification and chromosomal deviations in malignant human gliomas. (1987) (130)
In vivo cloning of PCR products in E. coli. (1993) (127)
Genetic mutations associated with cigarette smoking in pancreatic cancer. (2009) (126)
Genomic organization of the human PMS2 gene family. (1995) (125)
Analysis of masked mutations in familial adenomatous polyposis. (1999) (125)
Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation (2002) (125)
Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation (2010) (125)
Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. (2005) (125)
Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer. (2019) (123)
CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling (1999) (123)
Evaluation of the FHIT gene in colorectal cancers. (1996) (123)
The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT (2006) (123)
The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A (1991) (121)
Mutant proteins as cancer-specific biomarkers (2011) (117)
Applications of liquid biopsies for cancer (2019) (116)
APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis. (1997) (115)
Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer. (2022) (114)
A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype (1998) (114)
Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy (2018) (114)
TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI). (2004) (113)
Identifying markers for pancreatic cancer by gene expression analysis. (1998) (112)
NORF5/HUG1 Is a Component of theMEC1-Mediated Checkpoint Response to DNA Damage and Replication Arrest in Saccharomyces cerevisiae (1999) (109)
Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy. (2015) (108)
An analysis of genetic heterogeneity in untreated cancers (2019) (107)
Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution (2015) (105)
Mutant PIK 3 CA promotes cell growth and invasion of human cancer cells (2005) (102)
Remote loading of preencapsulated drugs into stealth liposomes (2014) (99)
PPAR d Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs (1999) (97)
Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells (2001) (97)
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. (2001) (95)
APC gene mutations in the mutation cluster region are rare in esophageal cancers. (1994) (95)
A multimodality test to guide the management of patients with a pancreatic cyst (2019) (94)
Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue. (2019) (94)
Targeting Vascular and Avascular Compartments of Tumors with C. novyi-NT and Anti-microtubule Agents (2004) (92)
Has the breast cancer gene been found? (1994) (92)
Characterization of human FAST-1, a TGF beta and activin signal transducer. (1998) (92)
Suppression of carcinogenesis in the intestines of min mice by the soybean-derived Bowman-Birk inhibitor. (1996) (92)
DEC1 is a downstream target of TGF-β with sequence-specific transcriptional repressor activities (2002) (89)
p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. (2000) (88)
Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas (2014) (88)
Design and analysis issues in genome-wide somatic mutation studies of cancer. (2009) (87)
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers (2006) (87)
Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists. (2020) (86)
Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma (2001) (85)
Imaging of Musculoskeletal Bacterial Infections by [124I]FIAU-PET/CT (2007) (83)
Mutations of the adenomatous polyposis coli gene in familial polyposis coli patients and sporadic colorectal tumors. (1991) (82)
Cancer therapy meets p53. (1994) (82)
Pharmacologic and toxicologic evaluation of C. novyi-NT spores. (2005) (80)
Patient-oriented gene set analysis for cancer mutation data (2010) (79)
Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction? (2016) (78)
Absence of secretory phospholipase A2 gene alterations in human colorectal cancer. (1995) (77)
Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line. (2001) (76)
Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis (2015) (75)
Precancerous neoplastic cells can move through the pancreatic ductal system (2018) (75)
Erratum: Genetic determinants of p53-induced apoptosis and growth arrest ((Genes and Development (1996) 10 (1945-1952)) (1996) (74)
Achilles' heel of cancer? (2001) (73)
Bispecific antibodies targeting mutant RAS neoantigens (2021) (73)
Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer. (2019) (72)
SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells. (2004) (71)
Counting alleles reveals a connection between chromosome 18q loss and vascular invasion (2001) (70)
Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke (2015) (70)
Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study (2015) (70)
IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients (2011) (69)
Amplification units containing human N-myc and c-myc genes. (1986) (68)
Asef , a Link Between the Tumor Suppressor APC and G-Protein Signaling (67)
Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia. (2011) (65)
Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma (2016) (65)
Exomic Sequencing of Four Rare Central Nervous System Tumor Types (2013) (65)
Genomic landscape and evolutionary trajectories of ovarian cancer precursor lesions (2019) (62)
Genetically Defined Subsets of Human Pancreatic Cancer Show Unique In Vitro Chemosensitivity (2012) (62)
Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells (2014) (61)
Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers. (2001) (60)
Clostridium novyi-NT can cause regression of orthotopically implanted glioblastomas in rats (2015) (59)
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. (2002) (59)
FAST-SeqS: A Simple and Efficient Method for the Detection of Aneuploidy by Massively Parallel Sequencing (2012) (59)
Aristolochic Acid in the Etiology of Renal Cell Carcinoma (2016) (59)
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. (1999) (58)
Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. (1993) (58)
Differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma with CT radiomics features. (2020) (57)
Genotyping by mass spectrometric analysis of short DNA fragments (1998) (57)
Identification of a Binding Partner for the Endothelial Cell Surface Proteins TEM7 and TEM7R (2004) (55)
Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study (2021) (55)
Lessons from Hereditary Review Colorectal Cancer (1996) (54)
A diaCEST MRI approach for monitoring liposomal accumulation in tumors. (2014) (53)
Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies (2020) (53)
A nanoparticle formulation that selectively transfects metastatic tumors in mice (2013) (51)
A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. (1992) (50)
Perceiving distance accurately by a directional process of integrating ground information (50)
Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. (1995) (50)
Hyper-recombination and genetic instability in BLM-deficient epithelial cells. (2003) (50)
Application of Deep Learning to Pancreatic Cancer Detection: Lessons Learned From Our Initial Experience. (2019) (50)
p 53-Dependent and independent expression of p 21 during cell growth , differentiation , and DNA damage (2007) (49)
Exome sequencing identifies frequent inactivating mutations in BAP 1 , ARID 1 A and PBRM 1 in intrahepatic cholangiocarcinomas (2014) (49)
X-rays strike p53 again (1994) (48)
Evaluation of Clostridium novyi-NT spores in dogs with naturally occurring tumors. (2012) (48)
Converting cancer genes into killer genes. (1996) (48)
Structural basis of nSH2 regulation and lipid binding in PI3Kα (2014) (48)
Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localised pancreatic cancer. (2019) (47)
Detection of Tumor DNA at the Margins of Colorectal Cancer Liver Metastasis (2011) (45)
Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket. (2008) (45)
GNAS Sequencing Identifies IPMN-specific Mutations in a Subgroup of Diminutive Pancreatic Cysts Referred to as “Incipient IPMNs” (2014) (45)
Polymerase delta variants in RER colorectal tumours. (1995) (45)
Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors. (1992) (44)
Spore Coat Architecture of Clostridium novyi NT Spores (2007) (42)
Annotated normal CT data of the abdomen for deep learning: Challenges and strategies for implementation. (2019) (42)
Revisiting the tumorigenesis timeline with a data-driven generative model (2019) (42)
Phosphorylation of β-Catenin at S33, S37, or T41 Can Occur in the Absence of Phosphorylation at T45 in Colon Cancer Cells (2003) (41)
Genetic Testing-- Present and Future (2000) (40)
Going mad with Smads. (1999) (39)
GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct. (2012) (39)
Familial and sporadic pancreatic cancer share the same molecular pathogenesis (2015) (39)
Monoallelic mutation analysis (MAMA) for identifying germline mutations (1995) (38)
Molecular cloning of the N-terminus of GTBP. (1996) (38)
Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin (2000) (38)
Identification and classification of p 53-regulated genes (1999) (37)
Assessing aneuploidy with repetitive element sequencing (2019) (37)
A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles (2011) (36)
Gene expression analysis goes digital (2007) (36)
Targeting public neoantigens for cancer immunotherapy (2021) (36)
High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma (2016) (35)
Diagnostic potential of tumor DNA from ovarian cyst fluid (2016) (35)
Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells. (2003) (35)
Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes (2015) (35)
High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder (2016) (34)
Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs) (2018) (34)
A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts (2017) (34)
The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies. (1995) (33)
Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (2019) (33)
Colorectal cancer and the intersection between basic and clinical research. (1994) (33)
Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements. (2002) (33)
Noninvasive imaging of infection after treatment with tumor‐homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI (2013) (32)
Discodermolide analogues as the chemical component of combination bacteriolytic therapy. (2005) (32)
Identification of microbial DNA in human cancer (2009) (32)
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints (2015) (31)
Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer (2014) (31)
PI3Kα Inhibitors That Inhibit Metastasis (2010) (30)
Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder. (2016) (30)
Incidence and Distribution of UroSEEK Gene Panel in a Multi-institutional Cohort of Bladder Urothelial Carcinoma (2019) (30)
Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia (2011) (30)
PAK1, a gene that can regulate p53 activity in yeast. (1995) (28)
Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations. (2019) (28)
Conversion of diploidy to haploidy - Individuals susceptible to multigene disorders may now be spotted more easily. (2000) (27)
Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder (2017) (26)
β-Catenin Mutations: Insights into the APC Pathway and the Power of Genetics. (2016) (26)
Deep lessons learned: Radiology, oncology, pathology, and computer science experts unite around artificial intelligence to strive for earlier pancreatic cancer diagnosis. (2020) (25)
Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology (2019) (25)
Selected reaction monitoring approach for validating peptide biomarkers (2017) (24)
Direct Detection and Quantification of Neoantigens (2019) (24)
Targeting loss of heterozygosity for cancer-specific immunotherapy (2021) (24)
Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis. (2012) (23)
Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model. (2016) (23)
Gene amplification in cancer: a molecular cytogenetic approach. (1986) (22)
Myxoid liposarcoma with t(12;16) (q13;p11) contains site-specific differences in methylation patterns surrounding a zinc-finger gene mapped to the breakpoint region on chromosome 12. (1990) (22)
The Structure of a Human p 110 a / p 85 a Complex Elucidates the Effects of Oncogenic PI 3 K a Mutations (2007) (22)
A gene for neurofibromatosis 2 (1993) (22)
Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes (2012) (22)
Cancer, crash sites, and the new genetics of neoplasia. (1999) (22)
Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma (2018) (22)
Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands (2021) (21)
In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3–14.1 (1989) (20)
Thiazolidinedione-Based PI3Kα Inhibitors: An Analysis of Biochemical and Virtual Screening Methods (2011) (19)
The colorectal cancer gene hunt: current findings. (1992) (19)
The Structure of a Human p110a/p85a Complex Elucidates the Effects of Oncogenic PI3Ka Mutations (2007) (18)
Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design. (2017) (18)
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection (2020) (18)
Serial circulating tumor DNA (ctDNA) analysis as a prognostic marker and a real-time indicator of adjuvant chemotherapy (CT) efficacy in stage III colon cancer (CC). (2018) (18)
Circulating tumor DNA (ctDNA) as a marker of recurrence risk in stage II colon cancer (CC). (2014) (18)
Alpha-1 adrenergic receptor antagonists for preventing acute respiratory distress syndrome and death from cytokine storm syndrome. (2020) (18)
Less death in the dying (1997) (17)
Large-scale identification of novel transcripts in the human genome. (2007) (17)
Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers (2021) (17)
The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality from COVID-19 (2020) (17)
Targeting the catecholamine-cytokine axis to prevent SARS-CoV-2 cytokine storm syndrome (2020) (17)
Effective expression of small interfering RNA in human cells (15)
Winning the War: Science Parkour (2012) (15)
The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations (2019) (15)
TCR β chain–directed bispecific antibodies for the treatment of T cell cancers (2021) (15)
Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations (2017) (15)
Presymptomatic direct detection of adenomatous polyposis coli (APC) gene mutations in familial adenomatous polyposis (1993) (14)
Potential role of circulating tumor DNA (ctDNA) in the early diagnosis and post-operative management of localised pancreatic cancer. (2017) (14)
Response to Comments on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers" (2007) (13)
Targeted deletion of Smad 4 shows it is required for transforming growth factor b and activin signaling in colorectal cancer cells (1998) (13)
Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM). (2016) (13)
Multicolor in vitro translation (2003) (13)
What's mice got to do with it? (1996) (12)
Advances in Brief p 53 Mutation and MDM 2 Amplification in Human Soft Tissue Sarcomas 1 (2006) (12)
Tumour-suppressor genes. X-rays strike p53 again. (1994) (12)
The potential of circulating tumor DNA (ctDNA) to guide adjuvant chemotherapy decision making in locally advanced rectal cancer (LARC). (2017) (12)
The Xist RNA Gene Evolved in Eutherians by Pseudogenization of a Protein-Coding Gene (2006) (11)
Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase. (2004) (11)
The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19 (2021) (11)
STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA (2007) (11)
Knudson's hypothesis and the TP53 revolution (2003) (11)
Design, synthesis and evaluation of new RDP inhibitors (2003) (10)
Erratum: Counting alleles reveals a connection between chromosome 18q loss and vascular invasion (Nature. Biotechnol. (2001) 19 (78-81)) (2001) (10)
An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation (2019) (10)
Circulating tumor DNA (ctDNA) in nonmetastatic colorectal cancer (CRC): Potential role as a screening tool. (2015) (10)
SAM 1.1 and JOSH 4.4: two RFLPs within the human DCC gene. (1992) (10)
Mammalian cells resistant to tumor suppressor genes. (1996) (10)
Three dinucleotide repeat polymorphisms proximal to the D2S123 locus. (1994) (10)
Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine–resistant cancer cells (2005) (9)
Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy (2018) (9)
EcoRI polymorphism within the GLI gene (chromosome 12q13.3-14.1). (1990) (9)
Synthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 Kinase. (2012) (8)
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens (2021) (8)
Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett's Esophagus. (2021) (8)
The potential of circulating tumor DNA (ctDNA) to reshape the design of clinical trials testing adjuvant therapy in patients with early stage cancers. (2016) (8)
Genetic landscape of extreme responders with anaplastic oligodendroglioma (2017) (8)
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer (2021) (7)
Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints (2015) (6)
The Role of hPMS 1 and hPMS 2 in Predisposing to Colorectal Cancer 1 (2001) (6)
GNAS Codon 201 mutations are uncommon in Intraductal Papillary Neoplasms of the Bile Duct (2012) (6)
Breast and Colorectal Cancers The Consensus Coding Sequences of Human (2007) (6)
Intraductal papillary mucinous neoplasm in a neonate with congenital hyperinsulinism and a de novo germline SKIL gene mutation. (2015) (5)
Circulating tumor DNA as a prognostic biomarker in early stage pancreatic cancer. (2018) (5)
318MO Circulating tumour DNA (ctDNA) dynamics, CEA and sites of recurrence for the randomised DYNAMIC study: Adjuvant chemotherapy (ACT) guided by ctDNA analysis in stage II colon cancer (CC) (2022) (5)
Non-invasive detection of bladder cancer through the analysis of driver gene mutations and aneuploidy (2017) (5)
Glioblastoma Multiforme An Integrated Genomic Analysis of Human (2010) (5)
Classification of pancreatic cystic neoplasms using radiomic feature analysis is equivalent to an experienced academic radiologist: a step toward computer-augmented diagnostics for radiologists (2022) (4)
Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma (2013) (4)
Tech.sight. Genetic testing--present and future. (2000) (4)
Tumor DNA as a Cancer Biomarker through the Lens of Colorectal Neoplasia (2020) (3)
Circulating tumor DNA as a cancer biomarker (2008) (3)
The FELIX Project: Deep Networks To Detect Pancreatic Neoplasms (2022) (3)
“Abstracts of the 77th Annual Meeting of the Japanese Cancer Association; 2018 Sept 27‐29; Osaka, Japan” as Cancer Science, Supplement 2, Vol 109 (2018) (2018) (3)
Through the Glass Lightly (1995) (3)
Targeted Inactivation of p 53 in Human Cells Does Not Result in Aneuploidy 1 (2002) (3)
Response to Comments on “The Predictive Capacity of Personal Genome Sequencing” (2012) (3)
Cancer. A gene for neurofibromatosis 2. (1993) (3)
Abstract 20: Whole exome sequencing of aristolochic acid induced upper urothelial carcinomas. (2012) (2)
PAK 1 , a gene that can regulate p 53 activity in yeast ( tumor suppressor / transactivation / posttranslational modification / phosphorylation ) (2005) (2)
The treatment of tumors (2004) (2)
Structural basis of nSH 2 regulation and lipid binding in PI 3 Kα (2014) (2)
A pooled analysis of multicenter cohort studies of post-surgery circulating tumor DNA (ctDNA) in early stage colorectal cancer (CRC). (2019) (2)
Erratum to "Annotated normal CT data of the abdomen for deep learning: Challenges and strategies for implementation" [Diagn. Interv. Imaging. 101 (2020) 35-44]. (2020) (2)
Massively parallel sequencing (MPS) of circulating DNA in patients with metastatic colorectal cancer (mCRC): Prognostic significance and early changes during chemotherapy (CT). (2013) (2)
Abstract 4137: Clonal evolution defines the natural history of metastatic pancreatic cancer (2015) (2)
Material for The Antisense Transcriptomes of Human Cells (2008) (2)
Nuclear reprogramming and the cancer genome (2013) (2)
PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity (2015) (2)
Necessity Is the Mother of Invention: The Development of Digital Genomics. (2016) (2)
Insertion/Deletion Polymorphism and Other Restriction Fragment Length Polymorphisms in the MCC Gene (1992) (2)
Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs ( NSAIDs ) in colon cancer cells (2004) (2)
Author response: Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection (2021) (2)
The Genetic Evolution of Melanoma. (2016) (2)
Abstracts of the 32nd Annual American Cytogenetics Conference (1995) (2)
An analysis of genetic heterogeneity in untreated cancers (2019) (1)
Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (2019) (1)
TCR-mimic bispecific antibodies to target the HIV-1 reservoir (2022) (1)
An interview with Bert Vogelstein and Kenneth Kinzler. (2015) (1)
Abstract IA17: Non-invasive detection of somatic mutations in the management of CRC (2017) (1)
Non-invasive detection of upper tract urothelial carcinomas through the analysis of driver gene mutations and aneuploidy in urine (2017) (1)
Author Correction: Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers (2021) (1)
Advances in Brief Cell Surface Tumor Endothelial Markers Are Conserved in Mice and Humans 1 (2001) (1)
Correction to: Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology (2022) (1)
Targeting MHC-linked wild type p53 with TCR mimic single chain diabody for cancer immunotherapy. (2019) (1)
ET-58THE GENETICALLY ENGINEERED CLOSTRIDIUM NOVYI-NT IS EFFICACIOUS IN THE TREATMENT OF INTRACRANIAL GLIOBLASTOMAS. (2014) (1)
13 Chromosomes and gene amplification in malignant human gliomas (MHG) (1987) (1)
Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma (2018) (1)
Abstract 2225: The molecular architecture of p85α as determined by SAXS and chemical cross-linking. (2013) (1)
p2! Is Necessary for the p53-mediated G, Arrest in Human Cancer Cells' (2006) (1)
Alpha-1 adrenergic receptor antagonists prevent acute respiratory distress syndrome and death: implications for Coronavirus disease 2019 (2020) (1)
Abstract 2628: Genome-wide sequencing identifiesATMas a pancreatic cancer susceptibility gene (2012) (1)
Advances in Brief X-Linked Inhibitor of Apoptosis Protein ( XIAP ) Is a Nonredundant Modulator of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand ( TRAIL )-Mediated Apoptosis in Human Cancer Cells (2004) (1)
Mononucleotide Repeat Sequence Variability in Mismatch Repair-deficient Cancers 1 (2001) (1)
Software for Assessing aneuploidy with repetitive element sequencing (2020) (1)
Supplement to: cancer associated mutations in non-cancer associated endometriosis (2017) (0)
Ewing et al. Suppl. Fig. 3 (2015) (0)
The Big Data cancer results are reported in Bert (0)
Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules. (2023) (0)
Mutation-based detection of molecular tumor margins in colorectal liver metastasis. (2010) (0)
PIK3CA gene mutations in human cancers (2005) (0)
Abstract LB095: Hybrid TCR-CAR design surpasses conventional CARs and patient-derived TCRs in targeting an ultra-low-density neoantigen (2023) (0)
Author Correction: Targeting public neoantigens for cancer immunotherapy (2021) (0)
Abstract IA03: Lessons from colorectal cancer (2017) (0)
Abstract NG06: The Trojan Horse Strategy: Packaging chemotherapeutics can help alleviate toxicity (2015) (0)
Identification of Somatically Acquired Gene Mutations In the Kineome and Exome In CLL (2010) (0)
TheGLIGeneEncodes a Nuclear Protein WhichBindsSpecific Sequences intheHumanGenome (1990) (0)
Mountains and hills: A survey of the tumour landscape (2009) (0)
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY (2023) (0)
Advances in Brief HMSH 2 Mutations in Hereditary Nonpolyposis Colorectal Cancer Kindreds 1 (2006) (0)
Analysis of Circulating DNA Serial Assessment of Human Tumor Burdens in Mice by the (2007) (0)
with Phosphoserine Escherichia coli Expanding the Genetic Code of (2011) (0)
Waf1 anti-tumoral (1994) (0)
1197 Optimizing a T cell-engaging bispecific antibody targeting the highly recurrent p53 R175H neoantigen via affinity maturation (2022) (0)
Author response: Diagnostic potential of tumor DNA from ovarian cyst fluid (2016) (0)
Expression of p 53 and p 21 proteins in various cell lines (2007) (0)
UroSEEK signature in invasive bladder cancer (2018) (0)
Families Evaluable by Linkage (2007) (0)
Microsatellite Instability and Mutations of the Transforming Growth Factor @3 Type II Receptor Gene in Colorectal Cancer1 (2006) (0)
UROSEEK: A NOVEL NON‐INVASIVE MOLECULAR METHOD FOR EARLY DETECTION OF BLADDER CANCER: MP65‐13 (2018) (0)
Abstract IA05: ctDNA and MRD in colorectal cancer: Time to reinvent adjuvant clinical trials (2020) (0)
Huang Mutations α Effects of Oncogenic PI 3 K Complex Elucidates the α / p 85 α The Structure of a Human p 110 (2013) (0)
College News: AMERICAN COLLEGE OF MEDICAL GENETICS (2000) (0)
Precancerous neoplastic cells can move through the pancreatic ductal system (2018) (0)
Human Cancer Biology Detection of Tumor DNA at the Margins of Colorectal Cancer Liver Metastasis (2011) (0)
Abstract PR02: Targeting PI3K: The PIP2 binding site (2015) (0)
1213 Hydrophobic interactions underlie recognition of a KRAS G12V neoantigen by a TCR-mimic antibody (2022) (0)
UROSEEK: A NOVEL NON‐INVASIVE MOLECULAR ASSAY FOR SURVEILLANCE OF BLADDER CANCER: MP65‐14 (2018) (0)
Genetic landscape of extreme responders with anaplastic oligodendroglioma: NRG Oncology/RTOG 9402. (2016) (0)
Series analysis method of gene expression (1996) (0)
Abstracts of the 33rd Annual American Cytogenetics Conference (1995) (0)
Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1 (Journal for Immuno Therapy of Cancer (2019) 7 (40) DOI: 10.1186/s40425-018-0492-x) (2019) (0)
Abstract 127: The genomic landscapes of inflammatory bowel disease-associated colorectal cancers (2016) (0)
Author response: Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer (2020) (0)
Jihye Yun Pathway Mutations in Tumor Cells KRAS Glucose Deprivation Contributes to the Development of (2013) (0)
A apc mutation, which is associated with familial colon cancer at ashkenazi jews (1998) (0)
Inherited and somatic mutations of the APC gene in human colorectal cancer (1992) (0)
Direct Detection and Quantification of Neo-antigens (2019) (0)
597 Molecular Markers Help Define Cyst Type in the Pancreas: An International, Multicenter Study of Over 300 Cysts (2016) (0)
14 Renaturation gel analysis of amplified DNA sequences (1987) (0)
Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome (2018) (0)
Abstract PR3: Exome sequencing of head and neck squamous cell carcinoma reveals a higher frequency of mutations in TP53 among African Americans (2011) (0)
An isogenic cell line panel for sequence-based screening of targeted anticancer drugs (2021) (0)
Yac clones comprising 55 mb of dna at the fap locus 5q21 in six contigs allow localisation of polymorphic markers and candidate tumour suppressor genes (1991) (0)
Advances in Brief p 2 ! Is Necessary for the p 53-mediated G , Arrest in Human Cancer Cells ' (2006) (0)
Detection of rare mutations, copy number variation, and DNA methylation in the same template DNA molecules (2022) (0)
Familial and sporadic pancreatic cancer share the same molecular pathogenesis (2014) (0)
Abstract DL01-01: Cancer Genomes and their Implications for Early Detection (2013) (0)
Dna sequence amplification in a colon carcinoma cell line resistant to mitoxantrone (1986) (0)
Circulating tumor DNA reflects therapy response in colorectal cancer (2008) (0)
Epigenetic Profiling and Epigenetic Therapy in Cancer (2008) (0)
Progression ofColorectal CancerIsAssociated withMultiple Tumor Suppressor GeneDefects butInhibition ofTumorigenicity IsAccomplished byCorrection ofAnySingle Defect viaChromosome Transfer (1992) (0)
Book Listings (2001) (0)
Leary Patients with Whole-Genome Sequencing Detection of Chromosomal Alterations in the Circulation of Cancer (2012) (0)
catastrophe after DNA damage (1999) (0)
UvA-DARE ( Digital Academic Repository ) APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis (1998) (0)
Subject Index, Vol. 71 1995 (1995) (0)
Book Listings (2001) (0)
Consensus sequences coding for human breast and colorectal cancers (2007) (0)
Ewing et al. Suppl. Data 1 (2015) (0)
Abstract B004: sCD-3BP: An MCT-1-“gated” therapeutic for pancreatic adenocarcinoma (2022) (0)
Improved methods of beaming (2006) (0)
A retrospective clinical study supporting the rationale for trials of Alpha-1 Adrenoreceptor Antagonists to prevent cytokine storm and severe COVID-19 (2020) (0)
GLI3Encodes a 190-Kilodalton Protein withMultiple Regions ofGLISimilarity (1990) (0)
identifying cancer patients from GC-patterned fragment ends of cell-free DNA (2022) (0)
Converting cancer genes into killer genes (gene therapyyoncogeneytumor suppressor geneyp53) (1996) (0)
Bacteriolytic combination therapy for the treatment of tumors (2002) (0)
IL-2 AUGMENTS IMMTAC-DEPENDENT T CELL ACTIVATION AND TUMOUR CELL KILLING TARGETING A SHARED TP53 NEOANTIGEN WITH BISPECIFIC T CELL RETARGETING ANTIBODY (2020) (0)
Non-invasive detection of bladder cancer through the analysis of driver gene 1 mutations and aneuploidy 2 3 (2017) (0)
Limits to the Human Cancer Genome Project ? (0)
Assignment of the Human p27Kipl Gene to 12pl3 and Its Analysis in Leukemias1 (1995) (0)
Correction: Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma (2017) (0)
44 MASSIVELY PARALLEL SEQUENCING OF ESOPHAGEAL BRUSHINGS ENABLES AN ANEUPLOIDY-BASED CLASSIFICATION OF PATIENTS WITH BARRETT'S ESOPHAGUS (0)
Abstract LB-257: Profiling the effects of IDH1 and IDH2 mutants on the glioma cell metabolome (2011) (0)
629 Targeting a shared TP53 neoantigen with bispecific T cell retargeting antibody (2020) (0)
Analysis of masked mutations in (2016) (0)
Seq-ing the SINEs of Central Nervous System Tumors in Cerebrospinal Fluid DNA (2022) (0)
University of Southern Denmark Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers (2018) (0)
Whole-Genome Analyses and Circulating Tumor DNA Approaches in Cancer (2013) (0)
A simplified system for herstelliung of recombinant adenoviruses (1999) (0)
Dissecting the specificity of a TCR-mimic antibody targeting TP53 R175H mutation-derived neoantigen (2020) (0)
Abstract LB-326: Structural basis of lipid-binding and regulation in PI3Kα (2014) (0)
2777 Lavage of the uterine cavity for early and differential diagnosis of serous ovarian cancer (2015) (0)
Exomic sequencing of pancreatic neuroendocrine tumors: Detection of alterations in chromatin remodeling and mTOR pathway genes. (2011) (0)
Cancer in Predisposing to Colorectal hPMS 2 and hPMS 1 The Role of Updated Version (2001) (0)
Abstract NG01: Accumulation of somatic mutations in normal and cancerous tissues with age (2016) (0)

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