Kensuke Miyake
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Computer Science
Kensuke Miyake's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Kensuke Miyake's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4 (1999) (2067)
- Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4 (2002) (1388)
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4 (2013) (1142)
- Essential role of MD-2 in LPS responsiveness and TLR4 distribution (2002) (1076)
- Cutting Edge: Endotoxin Tolerance in Mouse Peritoneal Macrophages Correlates with Down-Regulation of Surface Toll-Like Receptor 4 Expression1 (2000) (831)
- Role of the Toll-like Receptor 4/NF-&kgr;B Pathway in Saturated Fatty Acid–Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages (2007) (726)
- Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition (1990) (659)
- Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis (1991) (646)
- Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. (2002) (640)
- The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase (2008) (608)
- Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long- term bone marrow cultures (1990) (598)
- Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages1 (2000) (519)
- Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. (2007) (514)
- Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. (2002) (469)
- Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. (2012) (445)
- Crystal Structures of Human MD-2 and Its Complex with Antiendotoxic Lipid IVa (2007) (442)
- Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia (2003) (442)
- A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture (1991) (413)
- Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response (2006) (391)
- Mouse Toll-like Receptor 4·MD-2 Complex Mediates Lipopolysaccharide-mimetic Signal Transduction by Taxol* (2000) (376)
- The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins [published erratum appears in J Cell Biol 1991 Feb;112(3):following 513] (1990) (373)
- Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain (2012) (366)
- Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. (2004) (345)
- The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells (2000) (336)
- Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 (2003) (330)
- Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling (2001) (328)
- Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. (2002) (317)
- Cutting Edge: Lipopolysaccharide Induces Physical Proximity Between CD14 and Toll-Like Receptor 4 (TLR4) Prior to Nuclear Translocation of NF-κB1 (2000) (310)
- Saccharomyces cerevisiae‐ and Candida albicans‐Derived Mannan Induced Production of Tumor Necrosis Factor Alpha by Human Monocytes in a CD14‐ and Toll‐Like Receptor 4‐Dependent Manner (2002) (292)
- B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells (1998) (278)
- Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands (2013) (278)
- Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2 (2012) (277)
- Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 (2015) (272)
- Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody (1992) (269)
- Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice1 (2002) (265)
- Toll-Like Receptor 4, But Not Toll-Like Receptor 2, Is a Signaling Receptor for Escherichia and Salmonella Lipopolysaccharides1 (2000) (262)
- Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling. (2008) (259)
- Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA. (2016) (258)
- Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition. (2001) (254)
- Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. (2004) (252)
- Toll-like receptor 8 senses degradation products of single-stranded RNA (2015) (245)
- MD-2 Enables Toll-Like Receptor 2 (TLR2)-Mediated Responses to Lipopolysaccharide and Enhances TLR2-Mediated Responses to Gram-Positive and Gram-Negative Bacteria and Their Cell Wall Components1 (2001) (238)
- RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. (1995) (226)
- Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis. (2004) (220)
- Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog (2009) (218)
- Inhibition of homodimerization of Toll-like receptor 4 by curcumin. (2006) (217)
- TLR accessory molecules. (2008) (214)
- Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. (2000) (213)
- Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide. (2002) (191)
- Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization. (2008) (183)
- Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts1 (2000) (179)
- Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. (2011) (179)
- Regulatory Roles for MD-2 and TLR4 in Ligand-Induced Receptor Clustering1 (2006) (174)
- A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses (2007) (174)
- Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing (2009) (172)
- Double-stranded RNA of intestinal commensal but not pathogenic bacteria triggers production of protective interferon-β. (2013) (165)
- Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide from Porphyromonas gingivalis in Human Gingival Fibroblasts (2000) (164)
- Activation of Toll-Like Receptor 2 on Human Dendritic Cells Triggers Induction of IL-12, But Not IL-101 (2000) (160)
- Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea. (2006) (159)
- Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. (1998) (156)
- Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells (1994) (156)
- Roles for accessory molecules in microbial recognition by Toll-like receptors. (2006) (155)
- Cathepsins are required for Toll-like receptor 9 responses. (2008) (150)
- Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice (2002) (150)
- Involvement of very late activation antigen 4 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) in tumor necrosis factor alpha enhancement of experimental metastasis. (1994) (147)
- Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus (2012) (146)
- Requirement for VLA-4 and VLA-5 integrins in lymphoma cells binding to and migration beneath stromal cells in culture (1992) (143)
- Innate recognition of lipopolysaccharide by CD14 and toll-like receptor 4-MD-2: unique roles for MD-2. (2003) (142)
- CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. (2003) (140)
- Proteolysis of Human Monocyte CD14 by Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis Leading to Lipopolysaccharide Hyporesponsiveness1 (2000) (138)
- Monoclonal antibodies to CD44 and their influence on hyaluronan recognition (1995) (133)
- RP105 is associated with MD-1 and transmits an activation signal in human B cells. (1998) (131)
- Structural Analyses of Human Toll-like Receptor 4 Polymorphisms D299G and T399I* (2012) (131)
- The Role of IL-5 for Mature B-1 Cells in Homeostatic Proliferation, Cell Survival, and Ig Production 1 (2004) (127)
- Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway. (2002) (126)
- Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2. (2000) (122)
- Crystal structure of NOD2 and its implications in human disease (2016) (120)
- High-Density Lipoprotein Suppresses the Type I Interferon Response, a Family of Potent Antiviral Immunoregulators, in Macrophages Challenged With Lipopolysaccharide (2010) (120)
- Safflower polysaccharides activate the transcription factor NF-kappa B via Toll-like receptor 4 and induce cytokine production by macrophages. (2002) (118)
- IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate. (1990) (116)
- A Protein Associated with Toll-Like Receptor 4 (PRAT4A) Regulates Cell Surface Expression of TLR41 (2006) (115)
- Two waves of memory B-cell generation in the primary immune response. (2005) (114)
- Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. (2003) (113)
- Interaction of Soluble Form of Recombinant Extracellular TLR4 Domain with MD-2 Enables Lipopolysaccharide Binding and Attenuates TLR4-Mediated Signaling1 (2004) (110)
- Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci (2013) (110)
- Endotoxin recognition molecules, Toll-like receptor 4-MD-2. (2004) (110)
- The Molecular Mechanism of B Cell Activation by toll-like Receptor Protein RP-105 (1998) (107)
- DNase II-dependent DNA digestion is required for DNA sensing by TLR9 (2015) (101)
- Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling (2005) (100)
- The Radioprotective 105/MD-1 Complex Links TLR2 and TLR4/MD-2 in Antibody Response to Microbial Membranes1 (2005) (99)
- Innate recognition of lipopolysaccharide by Toll-like receptor 4/MD-2 and RP105/MD-1 (2000) (97)
- Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression. (2005) (97)
- Different Domains of Pseudomonas aeruginosa Exoenzyme S Activate Distinct TLRs1 (2004) (96)
- Cloning of murine and rat vascular cell adhesion molecule-1. (1992) (96)
- Nucleic acid‐sensing TLRs and autoimmunity: novel insights from structural and cell biology (2016) (94)
- Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent OK-432. (2003) (94)
- Regulatory molecules required for nucleotide‐sensing Toll‐like receptors (2009) (93)
- Cell activation by synthetic lipopeptides of the hepatitis C virus (HCV)--core protein is mediated by toll like receptors (TLRs) 2 and 4. (2002) (92)
- Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells. (2013) (92)
- Association of SIGNR1 with TLR4-MD-2 enhances signal transduction by recognition of LPS in gram-negative bacteria. (2005) (91)
- Trogocytosis of peptide–MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils (2017) (90)
- A Novel Synthetic Acyclic Lipid A-like Agonist Activates Cells via the Lipopolysaccharide/Toll-like Receptor 4 Signaling Pathway* (2001) (87)
- Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication. (2018) (84)
- Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease (2017) (84)
- CD38 ligation induces tyrosine phosphorylation of Bruton tyrosine kinase and enhanced expression of interleukin 5-receptor alpha chain: synergistic effects with interleukin 5. (1995) (84)
- An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing (2013) (83)
- Multifaceted roles of basophils in health and disease. (2017) (82)
- Role of TLR4/MD-2 and RP105/MD-1 in Innate Recognition of Lipopolysaccharide (2003) (81)
- Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll‐like receptor 4/MD‐2 complex signaling in a different manner (2012) (80)
- Toll‐like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation (2018) (78)
- A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5. (1997) (78)
- The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport (2018) (78)
- Emerging roles of basophils in allergic inflammation. (2017) (78)
- Guanosine and its modified derivatives are endogenous ligands for TLR7. (2016) (77)
- Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4. (2006) (75)
- Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. (2011) (72)
- Establishment and characterization of an immortal macrophage-like cell line inducible to differentiate to osteoclasts. (1998) (72)
- Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands. (2018) (69)
- The enzyme Cyp26b1 mediates inhibition of mast cell activation by fibroblasts to maintain skin-barrier homeostasis. (2014) (69)
- Mechanisms controlling nucleic acid-sensing Toll-like receptors (2018) (69)
- Antibody ligation of CD9 modifies production of myeloid cells in long-term cultures. (1996) (68)
- Mechanism of Anticancer Host Response Induced by OK-432, a Streptococcal Preparation, Mediated by Phagocytosis and Toll-Like Receptor 4 Signaling (2006) (67)
- Up-regulation of α4 integrin on activated langerhans cells: Analysis of adhesion molecules on langerhans cells relating to their migration from skin to draining lymph nodes (1993) (67)
- Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice (2016) (66)
- Basophils trigger emphysema development in a murine model of COPD through IL-4–mediated generation of MMP-12–producing macrophages (2018) (65)
- Lipopolysaccharide Preparation Extracted from Porphyromonas gingivalis Lipoprotein-Deficient Mutant Shows a Marked Decrease in Toll-Like Receptor 2-Mediated Signaling (2005) (62)
- Activation of CD44 induces ICAM‐1/LFA‐1‐independent, Ca2+, Mg2+, —independent adhesion pathway in lymphocyte‐endothelial cell interaction (1993) (62)
- TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells (2017) (61)
- RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins. (2009) (60)
- Serum Amyloid A3 Binds MD-2 To Activate p38 and NF-κB Pathways in a MyD88-Dependent Manner (2013) (60)
- Activation mediated by RP105 but not CD40 makes normal B cells susceptible to anti-IgM-induced apoptosis: a role for Fc receptor coligation (1996) (59)
- Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells. (1992) (58)
- Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases (2015) (57)
- UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5 (2014) (56)
- Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol (2001) (56)
- TLR4–MD-2 complex is negatively regulated by an endogenous ligand, globotetraosylceramide (2013) (55)
- The TLR4-TRIF Pathway Protects against H5N1 Influenza Virus Infection (2011) (55)
- Possible Involvement of Toll-Like Receptor 4 in Endothelial Cell Activation of Larger Vessels in Response to Lipopolysaccharide (2002) (54)
- B cells lacking RP105, a novel B cell antigen, in systemic lupus erythematosus. (1999) (54)
- Mast cell‐mediated immune responses through IgE antibody and Toll‐like receptor 4 by malarial peroxiredoxin (2008) (53)
- A monoclonal antibody against a murine CD38 homologue delivers a signal to B cells for prolongation of survival and protection against apoptosis in vitro: unresponsiveness of X-linked immunodeficient B cells. (1995) (53)
- Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses (2015) (52)
- Association of a tetraspanin CD9 with CD5 on the T cell surface: role of particular transmembrane domains in the association. (1999) (51)
- Chemical synthesis of Helicobacter pylori lipopolysaccharide partial structures and their selective proinflammatory responses. (2011) (51)
- Modulation of TCR-mediated signaling pathway by thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2). (1995) (50)
- Micrococcus luteus Teichuronic Acids Activate Human and Murine Monocytic Cells in a CD14- and Toll-Like Receptor 4-Dependent Manner (2001) (49)
- Characterization of autoantibody-secreting B cells in mice undergoing stimulatory (chronic) graft-versus-host reactions. Identification of a CD44hi population that binds specifically to hyaluronate. (1991) (48)
- Functional Association of CD9 with the Fcγ Receptors in Macrophages1 (2001) (48)
- Retinal cell type‐specific prevention of ischemia‐induced damages by LPS‐TLR4 signaling through microglia (2013) (48)
- Molecular cloning of a human RP105 homologue and chromosomal localization of the mouse and human RP105 genes (Ly64 and LY64). (1996) (48)
- Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment (2016) (48)
- Stromal cell CD9 regulates differentiation of hematopoietic stem/progenitor cells. (1999) (48)
- Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling (2004) (47)
- Combating herpesvirus encephalitis by potentiating a TLR3–mTORC2 axis (2018) (46)
- Effects of Overexpression of PTP36, a Putative Protein Tyrosine Phosphatase, on Cell Adhesion, Cell Growth, and Cytoskeletons in HeLa Cells* (1999) (46)
- Crystal structures of mouse and human RP105/MD-1 complexes reveal unique dimer organization of the toll-like receptor family. (2011) (45)
- The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation (2012) (45)
- Palmitoylation of LAT contributes to its subcellular localization and stability. (2006) (44)
- Intracellular TLR4/MD-2 in macrophages senses Gram-negative bacteria and induces a unique set of LPS-dependent genes. (2011) (44)
- Roles of the Cleaved N-Terminal TLR3 Fragment and Cell Surface TLR3 in Double-Stranded RNA Sensing (2014) (42)
- PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells. (2012) (42)
- ANALYSIS OF INFLAMMATORY ENDOTHELIAL CHANGES, INCLUDING VCAM‐1 EXPRESSION, IN MURINE CARDIAC GRAFTS1,2 (1993) (42)
- Highly restricted expression of a stromal cell determinant in mouse bone marrow in vivo (1992) (42)
- Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing. (2013) (42)
- Species-Specific Minimal Sequence Motif for Oligodeoxyribonucleotides Activating Mouse TLR9 (2015) (41)
- Toll-like receptors (TLRs) and immune disorders (2006) (41)
- Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8 (2016) (40)
- Activation-induced expression of thymic shared antigen-1 on T lymphocytes and its inhibitory role for TCR-mediated IL-2 production. (1994) (39)
- Endotoxin recognition molecules MD-2 and toll-like receptor 4 as potential targets for therapeutic intervention of endotoxin shock. (2004) (39)
- Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling (2019) (38)
- Difference in B cell activation between dermatomyositis and polymyositis: analysis of the expression of RP105 on peripheral blood B cells (2001) (38)
- Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function (2019) (37)
- The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane. (2014) (37)
- Recent advances in understanding basophil‐mediated Th2 immune responses (2017) (36)
- A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors. (2008) (36)
- RP105-lacking B cells from lupus patients are responsible for the production of immunoglobulins and autoantibodies. (2002) (35)
- CD44 and other cell interaction molecules contributing to B lymphopoiesis. (1993) (35)
- Shigella protein IpaH ( 9 . 8 ) is secreted from bacteria within mammalian cells and transported to the nucleus (2002) (35)
- Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis (2008) (34)
- A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. (2006) (34)
- Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A. (2013) (34)
- Physical and Functional Association between Thymic Shared Antigen-1/Stem Cell Antigen-2 and the T Cell Receptor Complex* (1998) (33)
- CD9 molecule expressed on stromal cells is involved in osteoclastogenesis. (1999) (32)
- A new cell adhesion mechanism involving hyaluronate and CD44. (1990) (32)
- Functional association of CD9 with the Fc gamma receptors in macrophages. (2001) (32)
- Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA (2017) (32)
- Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling (2016) (32)
- Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production. (2009) (30)
- Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α1 (2006) (29)
- The Role of Trogocytosis in the Modulation of Immune Cell Functions (2021) (28)
- How do basophils contribute to Th2 cell differentiation and allergic responses? (2018) (28)
- Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice (2018) (27)
- Emerging roles of the processing of nucleic acids and Toll‐like receptors in innate immune responses to nucleic acids (2017) (27)
- Homeostatic inflammation in innate immunity. (2014) (27)
- Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling. (2010) (27)
- Stromal-Cell and Cytokine-Dependent Lymphocyte Clones Which Span the Pre-B- to B-Cell Transition (1991) (27)
- Immunobiology of Acquired Resistance to Ticks (2020) (26)
- The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells. (2012) (26)
- Skin‐infiltrating basophils promote atopic dermatitis‐like inflammation via IL‐4 production in mice (2020) (26)
- A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells (2010) (25)
- Identification of genes expressed in tumor-associated macrophages. (2003) (25)
- Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites (2017) (25)
- Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling (2017) (25)
- Basophils and their effector molecules in allergic disorders (2020) (25)
- Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells (2013) (25)
- Toll-Like Receptor 4 Mediates the Antitumor Host Response Induced by a 55-Kilodalton Protein Isolated from Aeginetia indica L., a Parasitic Plant (2004) (24)
- Essential role of MD-2 in B-cell responses to lipopolysaccharide and Toll-like receptor 4 distribution (2002) (23)
- MD1 Expression Regulates Development of Regulatory T Cells (2006) (23)
- Mechanism regulating cell surface expression and activation of Toll-like receptor 4. (2006) (22)
- Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes. (2014) (21)
- Recognition of murine integrin beta 1 by a rat anti-stromal cell monoclonal antibody. (1994) (21)
- Involvement of CD14 in the inhibitory effects of dimethyl‐α‐cyclodextrin on lipopolysaccharide signaling in macrophages (2005) (21)
- The protective effect of the anti-Toll-like receptor 9 antibody against acute cytokine storm caused by immunostimulatory DNA (2017) (20)
- In vivo induction of IgG anti-DNA antibody by autoreactive mixed haplotype A beta z/A alpha d MHC class II molecule-specific CD4+ T-cell clones. (1994) (19)
- Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos (2017) (18)
- Endocytosis‐free DNA sensing by cell surface TLR9 in neutrophils: Rapid defense with autoimmune risks (2013) (17)
- E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates (2021) (17)
- Isolation of heptadepsin, a novel bacterial cyclic depsipeptide that inhibits lipopolysaccharide activity. (2004) (17)
- Functional role of CD44 (Pgp-1) on activated B cells (1991) (17)
- Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes. (2015) (17)
- MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN. (2004) (16)
- Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice. (2008) (16)
- Differentiation stages of eosinophils characterized by hyaluronic acid binding via CD44 and responsiveness to stimuli. (2001) (16)
- Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses (2015) (16)
- Crystal structure of human MD-2 in complex with lipid IVa (2007) (15)
- Toll-like receptors in COPD (2017) (15)
- Role of the endothelial adhesion molecule VCAM in murine cardiac allograft rejection. (1992) (15)
- Real-time imaging of mast cell degranulation in vitro and in vivo. (2016) (14)
- Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3–stimulated murine basophils (2019) (13)
- Biallelic Variants in CNPY3, Encoding an Endoplasmic Reticulum Chaperone, Cause Early-Onset Epileptic Encephalopathy. (2018) (13)
- Signal Transmission through MHC Class II Molecules in a Human B Lymphoid Progenitor Cell Line: Different Signaling Pathways Depending on the Maturational Stages of B Cells (1994) (13)
- Antiadhesive function of 130-kd glycoform of CD43 expressed in CD4 T-lymphocyte clones and transfectant cell lines. (2000) (13)
- Pre-B cells adhere to fibronectin via interactions of integrin α5/αv with RGDS as well as of integrin α4 with two distinct V region sequences at its different binding sites (1994) (13)
- Controlling systems of nucleic acid sensing-TLRs restrict homeostatic inflammation. (2012) (12)
- The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages. (2020) (12)
- Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes (2021) (11)
- Cleavage of Toll-Like Receptor 9 Ectodomain Is Required for In Vivo Responses to Single Strand DNA (2018) (11)
- Increase of RP105-lacking activated B cells in the peripheral blood and salivary glands in patients with Sjögren's syndrome. (2008) (11)
- Invited review: Roles for accessory molecules in microbial recognition by Toll-like receptors (2006) (11)
- Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line (2001) (10)
- Phospholipase A2 from Bee Venom Increases Poly(I:C)-induced Activation in Human Keratinocytes. (2020) (10)
- Up-regulation of alpha 4 integrin on activated Langerhans cells: analysis of adhesion molecules on Langerhans cells relating to their migration from skin to draining lymph nodes. (1993) (9)
- Role of a thymic stromal cell clone in inducing the stage-specific differentiation of various subpopulations of double negative thymocytes. (1991) (9)
- Structural basis for species‐specific activation of mouse Toll‐like receptor 9 (2018) (9)
- A calcium- or manganese-dependent epitope on the integrin beta 1 chain recognized by a unique mAb. (1994) (9)
- Murine Endothelial Cell Line Cells, F‐2: Interaction with Leukocytes and Cytokines Production (1993) (9)
- Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs (2018) (8)
- Association of SIGNR 1 with TLR 4 – MD2 enhances signal transduction by recognition of LPS in gram-negative bacteria (2005) (8)
- Nucleic acid-sensing Toll-like receptors: beyond ligand search. (2008) (8)
- Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase. (1998) (7)
- Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors (2021) (7)
- Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome (2019) (7)
- Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors (2019) (7)
- Inflammatory responses increase secretion of MD-1 protein. (2016) (7)
- Visualization of the Molecular Dynamics of Lipopolysaccharide on the Plasma Membrane of Murine Macrophages by Total Internal Reflection Fluorescence Microscopy* (2008) (7)
- New application of anti-TLR monoclonal antibodies: detection, inhibition and protection (2018) (7)
- Basophils, a neglected minority in the immune system, have come into the limelight at last. (2021) (6)
- Requirement of glycosylation machinery in TLR responses revealed by CRISPR/Cas9 screening (2017) (6)
- The role of basophils in acquired protective immunity to tick infestation (2020) (6)
- Nucleosides drive histiocytosis in SLC29A3 disorders by activating TLR7 (2019) (6)
- Evidence for existence of two distinct TNP-Ficoll-responsive B cell subpopulations preferentially reactive either to a T cell-replacing factor (B151-TRF) or to a signal from accessory cells. (1986) (5)
- Role of Basophils in a Broad Spectrum of Disorders (2022) (5)
- Epithelial membrane protein 3 (Emp3) downregulates induction and function of cytotoxic T lymphocytes by macrophages via TNF-α production. (2017) (5)
- STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes (2023) (5)
- Type I IFN Contributes to the Phenotype of Unc93b1D34A/D34A Mice by Regulating TLR7 Expression in B Cells and Dendritic Cells (2016) (5)
- Attenuates TLR4-Mediated Signaling Enables Lipopolysaccharide Binding and Extracellular TLR4 Domain with MD-2 Interaction of Soluble Form of Recombinant (2004) (5)
- TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes. (2020) (5)
- Pre-B cells adhere to fibronectin via interactions of integrin alpha 5/alpha V with RGDS as well as of integrin alpha 4 with two distinct V region sequences at its different binding sites. (1994) (5)
- C4b‐binding protein negatively regulates TLR4/MD‐2 response but not TLR3 response (2017) (5)
- Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus (2022) (4)
- Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting. (2020) (4)
- C4b binding protein negatively regulates TLR1/2 response (2017) (4)
- Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment (2022) (4)
- The CD9 Molecule on Stromal Cells (2000) (4)
- Gram-Negative Bacteria and Their Cell TLR 2-Mediated Responses to Gram-Positive Lipopolysaccharide and Enhances ( TLR 2 )-Mediated Responses to MD2 Enables Toll-Like Receptor 2 (2001) (4)
- N6-methylated adenine on the target sites of mamA from Mycobacterium bovis BCG enhances macrophage activation by CpG DNA in mice. (2020) (4)
- Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex (2017) (3)
- Polyclonal B cell activation by a B cell differentiation factor, B151-TRF2. II. Evidence for interaction of B151-TRF2 with glycoprotein on B cell membrane via recognition of terminal N-acetyl-D-glucosamine residue(s). (1986) (3)
- Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells (1998) (3)
- Cell Adhesion via Murine α4 Human β1 Integrin Chimera on Transfected K562 Cells to Endothelial Cells (1996) (3)
- [Toll-like receptors and their roles in defense responses against infection]. (2003) (2)
- [RP105 and B cell apoptosis]. (1996) (2)
- Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages. (2021) (2)
- Ligand-Induced Receptor Clustering Regulatory Roles for MD2 and TLR 4 in and Kensuke (2006) (2)
- PRAT 4 A-dependent expression of cell surface TLR 5 on neutrophils , classical monocytes and dendritic cells (2012) (2)
- CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development (2022) (2)
- CHAPTER 13. Nucleic Acid Innate Immune Receptors (2019) (2)
- Spontaneous and antibody directed cytotoxicity of double-negative T cells from autoimmune mice. (1993) (2)
- Its Expression Associated with RP 105 and Positively Regulates Mouse MD-1 , a Molecule That Is Physically (1998) (2)
- Participation of intercellular adhesion molecule-2 (CD102) in B lymphopoiesis. (2008) (2)
- [Functional roles of TLR4/MD-2 and RP105/MD-1 in innate recognition of LPS]. (2002) (2)
- Editorial overview: Special section: effects of endogenous immune stimulants: from a defence system against infection to a homeostatic mechanism linking metabolism with inflammation. (2014) (2)
- Rafts by Enhancing the Association of TCR with in T Cell Rafts Induce T Cell Costimulation Non-CD28 Costimulatory Molecules Present (2000) (2)
- Cell adhesion via murine alpha4 human beta1 integrin chimera on transfected K562 cells to endothelial cells. (1996) (2)
- Efficient isolation of mutant antigen presenting cell lines by functional selection using T cell clones. (1995) (2)
- Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1 (2022) (1)
- RP105 Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells (1998) (1)
- Infection in Mice tuberculosis Mycobacterium to Control Chronic Toll-Like Receptor 4 Expression Is Required (2002) (1)
- Myeloid differentiation protein‐2 has a protective role in house dust mite‐mediated asthmatic characteristics with the proinflammatory regulation of airway epithelial cells and dendritic cells (2021) (1)
- IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia (2022) (1)
- Molecular basis of regulatory effect of medicinal plant components on the innate immune response through TLR4 signaling (89.1) (2010) (1)
- Toll‐like Receptors (2009) (1)
- [Innate immune responses and inflammatory diseases via NLR-inflammasome]. (2012) (1)
- Toll-like receptor homolog RP 105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis (2015) (1)
- Dendritic Cells Triggers Induction of IL-12, Activation of Toll-Like Receptor 2 on Human (2013) (1)
- TNF-byMice from Acute Lethal Hepatitis Induced Agonistic Antibody to TLR 4 / MD2 Protects (2006) (1)
- Analysis of Vβ4 T cell receptor CDR3 repertoire in BALB/c and (NZB×NZW)F1 mice (1997) (1)
- Homeostatic Inflammation as Environmental-Adaptation Strategy (2016) (1)
- Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment. (2021) (1)
- HEMATOPOIESIS Stromal Cell CD 9 Regulates Differentiation of Hematopoietic Stem / Progenitor Cells (1999) (1)
- CORRIGENDUM: Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia (2005) (1)
- Highly efferocytic M2 macrophages are generated at the termination stage of basophil-dependent skin allergy and dampen the inflammation (2022) (0)
- Molecular mechanism for innate recognition of microbial products by toll-like receptors (2005) (0)
- TLR9-Mediated Innate Immune Responses Interacts with GRAMD4 and Regulates Endoplasmic Protein Nogo-B (RTN4-B) (2015) (0)
- Crystal structure of human TLR8 in complex with ORN06 (2015) (0)
- [Mechanisms regulating or dysregulating toll-like receptors in the steady or disease state]. (2012) (0)
- TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction (2023) (0)
- T-lymphocyte clones and transfectant cell lines Antiadhesive function of 130-kd glycoform of CD43 expressed in CD4 (2013) (0)
- [Microbial recognition mechanism in innate immune system]. (2005) (0)
- For Peer Review The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of TLR4/MD2 complex at the plasma membrane (2013) (0)
- Lipopolysaccharide Hyporesponsiveness Leading to Porphyromonas gingivalis Cysteine Proteinases ( Gingipains ) from Proteolysis of Human Monocyte CD 14 by Miyake (2000) (0)
- Expression of TLR4 4 (PRAT4A) Regulates Cell Surface A Protein Associated with Toll-Like Receptor (2013) (0)
- Unc93 homolog B1 regulates the balance of toll-like receptor 7 and toll-like receptor 9 responses reciprocally in dendritic cells (2009) (0)
- Translocation of NF-Toll-Like Receptor 4 ( TLR 4 ) Prior to Nuclear Physical Proximity Between CD 14 and Cutting Edge : Lipopolysaccharide Induces (2000) (0)
- This information is current as of Genomic DNA Motifs and Implications for the Recognition Selectivity of Human TLR 9 for Double CpG (2017) (0)
- Mouse Peritoneal Macrophages Toll-Like Receptor 4-MD2 Complex on Lipopolysaccharide Signaling Via the Cutting Edge : Cell Surface Expression and (2000) (0)
- Visualization of the molecular dynamics of LPS on the plasma membrane of murine macrophages by TIRFM (2008) (0)
- TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells (2017) (0)
- Analysis of Vbeta4 T cell receptor CDR3 repertoire in BALB/c and (NZB x NZW)F1 mice. (1997) (0)
- Chronic Obstructive Pulmonary Disease 3 Oral Presentations (2016) (0)
- Unc93 homolog B1 restricts systemic lethal inflammation by orchestrating TLR7 and TLR9 response (2012) (0)
- 6-Methyladenine may enhance immunostimulatory activity of bacterial genomic DNA (2020) (0)
- TLRs Exoenzyme S Activate Distinct aeruginosa Pseudomonas Different Domains of (2004) (0)
- [Toll-like receptors and its regulation]. (2005) (0)
- TLR7 promotes smoke-induced lung damage through the activity of mast cell tryptase (2020) (0)
- term cultures Antibody ligation of CD9 modifies production of myeloid cells in long (2011) (0)
- ANTICORPS ANTI-TLR9, COMPOSITION PHARMACEUTIQUE ET KIT (2018) (0)
- Regulatory T Cells MD1 Expression Regulates Development of (0)
- Guanosine and its analogs are endogenous ligands for TLR7 (2016) (0)
- Receptor 4 Expression Down-Regulation of Surface Toll-Like Peritoneal Macrophages Correlates with Cutting Edge: Endotoxin Tolerance in Mouse (2000) (0)
- ADP-ribosylation factor-like 8b is required for the development of mouse models of systemic lupus erythematosus (2019) (0)
- Toll-like receptors, session 2 (WS-001b) Chairpersons: Osamu Takeuchi, Myung-Shik Lee (2010) (0)
- Aggregation makes a protein allergenic at the challenge phase of basophil-mediated allergy in mice (2018) (0)
- TLRsExoenzyme S Activate Distinct Different Domains of Pseudomonas (2013) (0)
- Evidencefora RoleoftheIntegrinVLA 4 in Lympho-hemopoiesis (1991) (0)
- Effects of IL-5 on the expression of adhesion molecules on eosinophils (1994) (0)
- Combating herpesvirus encephalitis by potentiating a TLR3–mTORC2 axis (2018) (0)
- Immunity to helminth infection (PP-091) (2010) (0)
- in B lymphocytes CD19 regulates innate immunity by the toll-like receptor RP105 signaling (2013) (0)
- Human B Cells RP105 Is Associated With MD-1 and Transmits an Activation Signal in (2013) (0)
- The role of mTOR in TLR3 responses (2016) (0)
- Differential requirements of CD14 and Lipopolysaccharide Binding Protein in Monophosphoryl lipid A-mediated TLR4 activation (P1209) (2013) (0)
- Toll-like receptors (PP-001) (2010) (0)
- [Roles of Toll-like receptors and associated MD molecules in innate recognition of lipopolysaccharides]. (2001) (0)
- MyD 88-Dependent Manner B Pathways in a κ p 38 and NF-Serum Amyloid A 3 Binds MD2 To Activate (2013) (0)
- Production Homeostatic Proliferation , Cell Survival , and The Role of IL-5 for Mature B-1 Cells in Kiyoshi (2004) (0)
- TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells (135.4) (2009) (0)
- New application of anti-TLR monoclonal antibodies: detection, inhibition and protection (2018) (0)
- The anti-TLR4 monoclonal antibody Sa15-21 enhances inflammatory cytokine production in LPS-stimulated macrophages. (2023) (0)
- The Origin of Antibody‐Forming Cells Detected in the Bone Marrow after Thymus‐Independent Antigen‐Stimulation and Abnormality in Migration of B Cells of X‐Linked Immunodeficient CBA/N Mice (1987) (0)
- Response to Microbial Membranes Links TLR2 and TLR4/MD-2 in Antibody The Radioprotective 105/MD-1 Complex (2005) (0)
- TLR7/8 stress response drives histiocytosis in SLC29A3 disorders (2022) (0)
- antibody MAR-1 depletes basophils and cross-reacts with myeloid cells through its Fc portion (2021) (0)
- lymphocyte clones and transfectant cell lines Antiadhesive function of 130-kd glycoform of CD 43 expressed in CD 4 (2000) (0)
- The effect of core fucosylation on TLR4 function. (2015) (0)
- Structural studies of nucleic acid sensing Toll-like receptor (2014) (0)
- Toll-like receptor 7 promotes cigarette-smoke induced emphysema-like alveolar enlargement in chronic obstructive pulmonary disease (2016) (0)
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What Schools Are Affiliated With Kensuke Miyake?
Kensuke Miyake is affiliated with the following schools:
