Kevin J. Tracey

Q: What Schools Are Affiliated With Kevin J. Tracey

Kevin J. Tracey is affiliated with the following schools: University of Pittsburgh, University of California, San Francisco, Karolinska Institute, University of Utah, Boston University, Central South University, Albert Einstein College of Medicine, Boston College, University of Chicago

Kevin J. Tracey's AcademicInfluence.com Rankings

Kevin J. Tracey

Biology

#1659

World Rank

#2715

Historical Rank

#805

USA Rank

Neuroscience

#165

World Rank

#174

Historical Rank

#71

USA Rank

biology Degrees

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Biology

Kevin J. Tracey's Degrees

Doctorate Medicine Boston University
PhD Neurobiology Boston University

Why Is Kevin J. Tracey Influential?

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According to Wikipedia, Kevin J. Tracey, a neurosurgeon and inventor, is the president and CEO of the Feinstein Institute for Medical Research, professor of neurosurgery and molecular medicine at the Zucker School of Medicine, and president of the Elmezzi Graduate School of Molecular Medicine in Manhasset, New York. The Public Library of Science Magazine, PLOS Biology, recognized Tracey in 2019 as one of the most cited researchers in the world.

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Kevin J. Tracey's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin (2000) (3416)
The inflammatory reflex (2002) (3078)
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation (2002) (2847)
Shock and tissue injury induced by recombinant human cachectin. (1986) (2564)
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia (1987) (2498)
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal (2005) (2419)
High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes (2000) (1439)
Physiology and immunology of the cholinergic antiinflammatory pathway. (2007) (1357)
HMGB1 is a therapeutic target for sterile inflammation and infection. (2011) (1218)
Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. (1991) (1211)
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis (2004) (1153)
Reversing established sepsis with antagonists of endogenous high-mobility group box 1 (2003) (1142)
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion (2005) (1112)
Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit (2011) (1102)
Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. (1994) (1098)
Reflex control of immunity (2009) (1000)
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia (1993) (861)
Tumor necrosis factor, other cytokines and disease. (1993) (826)
Endogenous HMGB1 regulates autophagy (2010) (817)
HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2 (2006) (816)
Sepsis: a roadmap for future research. (2015) (775)
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release (2010) (752)
Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation (1988) (744)
Novel role of PKR in inflammasome activation and HMGB1 release (2012) (679)
Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats (2003) (658)
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia (1989) (646)
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis (2016) (640)
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation (2002) (609)
Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia (2008) (607)
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release (2012) (593)
Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis (2006) (593)
The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation (2003) (581)
The vagus nerve and the inflammatory reflex—linking immunity and metabolism (2012) (581)
Sepsis definitions: time for change (2013) (572)
Cytokine appearance in human endotoxemia and primate bacteremia. (1988) (548)
Cutting Edge: HMG-1 as a Mediator of Acute Lung Inflammation1 (2000) (543)
The cytokine activity of HMGB1 (2005) (528)
Sepsis: current dogma and new perspectives. (2014) (513)
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. (2003) (504)
The cholinergic anti-inflammatory pathway (2005) (495)
Pharmacological Stimulation of the Cholinergic Antiinflammatory Pathway (2002) (494)
The many faces of HMGB1: molecular structure‐functional activity in inflammation, apoptosis, and chemotaxis (2013) (481)
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation (2005) (481)
Activation of gene expression in human neutrophils by high mobility group box 1 protein. (2003) (452)
High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization (2004) (450)
Drug discovery: A jump-start for electroceuticals (2013) (447)
Peptide Regulatory Factors CACHECTIN/TUMOUR NECROSIS FACTOR (1989) (435)
The "cytokine profile": a code for sepsis. (2005) (431)
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock* (2005) (426)
Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia (2010) (425)
Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. (1987) (422)
HMGB1 Release and Redox Regulates Autophagy and Apoptosis in Cancer Cells (2010) (418)
Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1) (2012) (414)
Alarmins: awaiting a clinical response. (2012) (413)
High mobility group box‐1 protein induces the migration and activation of human dendritic cells and acts as an alarmin (2007) (388)
The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. (2006) (381)
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway (2009) (377)
Mechanisms and Therapeutic Relevance of Neuro-immune Communication. (2017) (377)
The HMGB1 Receptor RAGE Mediates Ischemic Brain Damage (2008) (371)
Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat (1997) (359)
Selective &agr;7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis* (2007) (354)
Macrophage inflammatory protein 1 modulates macrophage function. (1992) (339)
Reflex principles of immunological homeostasis. (2012) (335)
Structural Basis for the Proinflammatory Cytokine Activity of High Mobility Group Box 1 (2003) (335)
Targeting HMGB1 in inflammation. (2010) (333)
Rethinking inflammation: neural circuits in the regulation of immunity (2012) (329)
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice. (2002) (324)
Tumor necrosis factor: An updated review of its biology (1993) (315)
The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis. (2005) (313)
A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen (2013) (313)
HMGB1 as a DNA‐binding cytokine (2002) (312)
Neural reflexes in inflammation and immunity (2012) (309)
Neural regulation of immunity: molecular mechanisms and clinical translation (2017) (306)
IFN-γ Induces High Mobility Group Box 1 Protein Release Partly Through a TNF-Dependent Mechanism1 (2003) (306)
A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats (2001) (304)
The Endotoxin Delivery Protein HMGB1 Mediates Caspase‐11‐Dependent Lethality in Sepsis (2018) (303)
Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia. (2006) (300)
JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation (2014) (295)
Spermine Inhibits Proinflammatory Cytokine Synthesis in Human Mononuclear Cells: A Counterregulatory Mechanism that Restrains the Immune Response (1997) (295)
Modulation of TNF Release by Choline Requires α7 Subunit Nicotinic Acetylcholine Receptor-Mediated Signaling (2008) (294)
Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation (2000) (294)
Hemorrhagic Shock Induces NAD(P)H Oxidase Activation in Neutrophils: Role of HMGB1-TLR4 Signaling1 (2007) (293)
Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis (2013) (288)
ISO-1 Binding to the Tautomerase Active Site of MIF Inhibits Its Pro-inflammatory Activity and Increases Survival in Severe Sepsis* (2005) (280)
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis * (2007) (277)
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins. (1989) (277)
Expression of TNF and TNF Receptors (p55 and p75) in the Rat Brain after Focal Cerebral Ischemia (1997) (276)
Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120 (2000) (268)
MD-2 is required for disulfide HMGB1–dependent TLR4 signaling (2015) (267)
Network of Dynamic Interactions between Histone H1 and High-Mobility-Group Proteins in Chromatin (2004) (265)
RR Interval Variability Is Inversely Related to Inflammatory Markers: The CARDIA Study (2007) (259)
HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. (2013) (252)
ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO (2009) (250)
Molecular and Functional Neuroscience in Immunity. (2018) (247)
DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury (2015) (244)
Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality. (1990) (238)
Role of HMGB1 in apoptosis-mediated sepsis lethality. (2006) (236)
Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia. (1990) (234)
ELEVATED HIGH-MOBILITY GROUP BOX 1 LEVELS IN PATIENTS WITH CEREBRAL AND MYOCARDIAL ISCHEMIA (2006) (230)
The microbiota regulate neuronal function and fear extinction learning (2019) (227)
Anti-HMGB1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock (2006) (225)
Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion. (2002) (219)
The Neurology of the Immune System: Neural Reflexes Regulate Immunity (2009) (217)
Famotidine Use Is Associated With Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study (2020) (212)
Systemic inflammation and remote organ injury following trauma require HMGB1. (2007) (212)
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis* (2007) (206)
Abruptio placentae associated with cocaine use. (1983) (204)
Controlling inflammation: the cholinergic anti-inflammatory pathway. (2006) (196)
Role of HMGB1 in apoptosis-mediated sepsis lethality (2006) (195)
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14‐ and TNF‐dependent mechanisms (2004) (193)
TUMOR NECROSIS FACTOR IS A BRAIN DAMAGING CYTOKINE IN CEREBRAL ISCHEMIA (1997) (192)
Cachectin/tumour necrosis factor. (1989) (189)
IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism. (2003) (189)
Neural circuitry and immunity (2015) (188)
HMGB1 Mediates Cognitive Impairment in Sepsis Survivors (2012) (187)
The Selective α7 Agonist GTS-21 Attenuates Cytokine Production in Human Whole Blood and Human Monocytes Activated by Ligands for TLR2, TLR3, TLR4, TLR9, and RAGE (2009) (183)
Cholinergic Anti-Inflammatory Pathway Activity and High Mobility Group Box-1 (HMGB1) Serum Levels in Patients with Rheumatoid Arthritis (2007) (182)
Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome (2015) (180)
Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock (1999) (180)
Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice. (2014) (176)
HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. (2014) (172)
Cachectin: a hormone that triggers acute shock and chronic cachexia. (1988) (171)
The role of cytokine mediators in septic shock. (1990) (169)
Malaria-specific metabolite hemozoin mediates the release of several potent endogenous pyrogens (TNF, MIP-1 alpha, and MIP-1 beta) in vitro, and altered thermoregulation in vivo. (1995) (167)
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia (1995) (167)
Neural regulators of innate immune responses and inflammation (2004) (166)
Understanding immunity requires more than immunology (2010) (166)
Lymphocyte-derived ACh regulates local innate but not adaptive immunity (2013) (166)
Cachetin/TNF-α in Septic Shock and Septic Adult Respiratory Distress Syndrome (1988) (164)
Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential (1986) (164)
Central cholinergic activation of a vagus nerve - to spleen circuit alleviates experimental colitis (2013) (160)
Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19? (2020) (155)
HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion. (2002) (154)
A Cardiovascular Drug Rescues Mice from Lethal Sepsis by Selectively Attenuating a Late-Acting Proinflammatory Mediator, High Mobility Group Box 11 (2007) (152)
HMGB 1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4 (2013) (152)
α7 Nicotinic Acetylcholine Receptor Signaling Inhibits Inflammasome Activation by Preventing Mitochondrial DNA Release (2014) (151)
HMG‐1 REDISCOVERED AS A CYTOKINE (2001) (151)
Regulation of HMGB1 release by inflammasomes (2013) (149)
A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation (2011) (147)
Recombinant HMGB1 with cytokine-stimulating activity. (2004) (141)
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. (2003) (140)
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. (2011) (140)
Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone (1996) (138)
Roadmap for the Emerging Field of Cancer Neuroscience (2020) (136)
Cytokine production in a model of wound healing: the appearance of MIP-1, MIP-2, cachectin/TNF and IL-1. (1990) (136)
Cholinergic agonists attenuate renal ischemia-reperfusion injury in rats. (2008) (135)
Fetuin (α2-HS-glycoprotein) opsonizes cationic macrophagedeactivating molecules (1998) (135)
HMGB1 as a cytokine and therapeutic target (2002) (131)
Dual roles for HMGB1: DNA binding and cytokine (2001) (130)
α7 Nicotinic Acetylcholine Receptor (α7nAChR) Expression in Bone Marrow-Derived Non-T Cells Is Required for the Inflammatory Reflex (2012) (128)
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. (2005) (127)
Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review (2014) (125)
Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury. (2007) (125)
Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity (2018) (124)
High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow–derived Macrophages (2014) (124)
The Inflammatory Reflex and the Role of Complementary and Alternative Medical Therapies (2009) (124)
Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human subjects. Influence of elicited hormones and cytokines. (1989) (123)
Cutting Edge: High-Mobility Group Box 1 Preconditioning Protects against Liver Ischemia-Reperfusion Injury1 (2006) (122)
An Inhibitor of Macrophage Arginine Transport and Nitric Oxide Production (CNI-1493) Prevents Acute Inflammation and Endotoxin Lethality (1995) (121)
Immunologic Role of the Cholinergic Anti‐Inflammatory Pathway and the Nicotinic Acetylcholine α7 Receptor (2005) (114)
Metabolic Responses to Cachectin/TNF (1990) (112)
Cerebral Ischemia Enhances Polyamine Oxidation: Identification of Enzymatically Formed 3-Aminopropanal as an Endogenous Mediator of Neuronal and Glial Cell Death (1998) (111)
Famotidine use and quantitative symptom tracking for COVID-19 in non-hospitalised patients: a case series (2020) (109)
The Critical Role of p38 MAP Kinase in T Cell HIV-1 Replication (1997) (109)
Aerobic exercise attenuates inducible TNF production in humans. (2007) (106)
Cholinergic Neural Signals to the Spleen Down-Regulate Leukocyte Trafficking via CD11b1 (2009) (106)
C1q and HMGB1 reciprocally regulate human macrophage polarization. (2016) (105)
Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity. (1991) (105)
HMGB1 in Sepsis (2003) (103)
Tumor necrosis factor (cachectin) in the biology of septic shock syndrome. (1991) (101)
Endogenous HMGB 1 regulates autophagy (2010) (100)
A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins (2014) (100)
Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor. (2008) (100)
CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency. (1996) (99)
Splenectomy Protects against Sepsis Lethality and Reduces Serum HMGB1 Levels1 (2008) (96)
Galantamine Alleviates Inflammation and Other Obesity-Associated Complications in High-Fat Diet-Fed Mice (2011) (96)
Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation (2019) (95)
Inhibition of High-Mobility Group Box 1 Protein (HMGB1) Enhances Bacterial Clearance and Protects against Pseudomonas Aeruginosa Pneumonia in Cystic Fibrosis (2012) (95)
Essential Neuroscience in Immunology (2017) (94)
Tumor necrosis factor (1993) (92)
High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis. (2003) (92)
High Mobility Group Box Protein-1 Correlates with Renal Function in Chronic Kidney Disease (CKD) (2008) (92)
Immature Dendritic Cell-Derived Exosomes Rescue Septic Animals Via Milk Fat Globule Epidermal Growth Factor VIII (2009) (91)
HMGB1 is a bone‐active cytokine (2008) (91)
It takes nerve to dampen inflammation (2005) (90)
Spermine Protects Mice Against Lethal Sepsis Partly by Attenuating Surrogate Inflammatory Markers (2009) (89)
A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice (2016) (89)
Regulation of Posttranslational Modifications of HMGB1 During Immune Responses. (2016) (88)
Tumor Necrosis Factor and Regulation of Metabolism in Infection: Role of Systemic versus Tissue Levels (1992) (88)
Ethanol Blocks Leukocyte Recruitment and Endothelial Cell Activation In Vivo and In Vitro1 (2004) (88)
Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. (2009) (85)
IL-1α and IL-1β Are Endogenous Mediators Linking Cell Injury to the Adaptive Alloimmune Response1 (2007) (85)
Cytokine-specific Neurograms in the Sensory Vagus Nerve (2016) (85)
Cerebroprotective effects of aminoguanidine in a rodent model of stroke. (1996) (85)
Brain Region-Specific Alterations in the Gene Expression of Cytokines, Immune Cell Markers and Cholinergic System Components during Peripheral Endotoxin-Induced Inflammation (2014) (84)
Neural inhibition of inflammation: the cholinergic anti-inflammatory pathway (2003) (83)
Vagus nerve stimulation attenuates the systemic in ̄ ammatory response to endotoxin (82)
Fetuin protects the fetus from TNF (1997) (81)
Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. (2016) (78)
Mind over immunity (2001) (78)
Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis. (2005) (77)
High mobility group box 1 (HMGB1) (2005) (77)
Identification of Hemopexin as an Anti-Inflammatory Factor That Inhibits Synergy of Hemoglobin with HMGB1 in Sterile and Infectious Inflammation (2012) (76)
Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis (2012) (76)
Central Muscarinic Cholinergic Activation Alters Interaction between Splenic Dendritic Cell and CD4+CD25- T Cells in Experimental Colitis (2014) (74)
Loss of NF-κB Activity during Cerebral Ischemia and TNF Cytotoxicity (1999) (71)
Choline acetyltransferase–expressing T cells are required to control chronic viral infection (2019) (70)
Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent. (1998) (70)
Peripheral Administration of Fetuin-A Attenuates Early Cerebral Ischemic Injury in Rats (2010) (70)
Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation (2019) (70)
High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice. (2013) (69)
Inhibition of p38 mitogen activate kinase attenuates the severity of pancreatitis-induced adult respiratory distress syndrome (2000) (68)
From CNI‐1493 to the immunological homunculus: physiology of the inflammatory reflex (2008) (68)
Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal (2002) (68)
Recombinant growth hormone enhances muscle myosin heavy-chain mRNA accumulation and amino acid accrual in humans. (1989) (67)
Lipopolysaccharide-Induced Cytokine Cascade and Lethality in LTα/TNFα-Deficient Mice (1997) (66)
Experimental Therapeutic Strategies for Severe Sepsis (2008) (65)
Novel Strategies for Targeting Innate Immune Responses to Influenza (2016) (65)
Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury. (1999) (63)
A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis (2016) (63)
Neural Signaling in the Spleen Controls B-Cell Responses to Blood-Borne Antigen (2012) (63)
Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation (2015) (62)
High-Mobility Group Box-1 Protein (HMGB1) Is Increased in Antineutrophilic Cytoplasmatic Antibody (ANCA)-Associated Vasculitis with Renal Manifestations (2011) (61)
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. (2003) (61)
Cachectin/tumor necrosis factor and other cytokines in infectious disease. (1989) (61)
It takes guts to grow a brain (2011) (61)
Targeting high mobility group box 1 as a late-acting mediator of inflammation. (2003) (59)
Fat meets the cholinergic antiinflammatory pathway (2005) (59)
Galantamine alleviates inflammation and insulin resistance in patients with metabolic syndrome in a randomized trial. (2017) (58)
In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin (2016) (58)
Cardiopulmonary Arrest and Resuscitation Disrupts Cholinergic Anti-Inflammatory Processes: A Role for Cholinergic α7 Nicotinic Receptors (2011) (58)
IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response. (2007) (57)
Single-Pulse and Unidirectional Electrical Activation of the Cervical Vagus Nerve Reduces Tumor Necrosis Factor in Endotoxemia (2015) (57)
HMGB1 as a mediator of necrosis-induced inflammation and a therapeutic target in arthritis. (2004) (56)
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase (2016) (55)
HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4 (2015) (55)
Dendritic cell activating peptides induce distinct cytokine profiles. (2006) (55)
The Aqueous Extract of a Popular Herbal Nutrient Supplement, Angelica sinensis, Protects Mice against Lethal Endotoxemia and Sepsis (2006) (55)
HMGB1 in the immunology of sepsis (not septic shock) and arthritis. (2004) (55)
Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors (2017) (54)
The effects of CpG DNA on HMGB1 release by murine macrophage cell lines (2005) (54)
Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype (54)
The physiologic consequences of macrophage pacification during severe acute pancreatitis. (1998) (54)
HMGB1 as a potential therapeutic target. (2007) (52)
High-mobility group box 1 protein is an inflammatory mediator in necrotizing enterocolitis: protective effect of the macrophage deactivator semapimod. (2005) (52)
HMGB1–C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis (2019) (52)
Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial (2020) (51)
Differential neutrophil activation before and after endotoxin infusion in enterally versus parenterally fed volunteers. (1988) (50)
Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake. (2012) (50)
Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in rats. (2001) (49)
High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia (2013) (49)
Small molecule inhibition of tumor necrosis factor gene processing during acute pancreatitis prevents cytokine cascade progression and attenuates pancreatitis severity. (1997) (49)
Targeting neural reflex circuits in immunity to treat kidney disease (2017) (49)
Identification of a brainstem locus that inhibits tumor necrosis factor (2020) (47)
The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis. (2006) (47)
Lipid unites disparate syndromes of sepsis (2004) (47)
Reflexes in Immunity (2016) (46)
High-Mobility Group Box 1 Mediates Persistent Splenocyte Priming in Sepsis Survivors: Evidence From a Murine Model (2013) (46)
Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation (2019) (46)
Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII (The Journal of Immunology (2009) 183, (5983-5990)) (2009) (46)
Tumor necrosis factor-enhanced leukotriene B4 generation and chemotaxis in human neutrophils. (1988) (45)
A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve (2017) (45)
Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear (2019) (45)
Characterization of inflammation and insulin resistance in high‐fat diet‐induced male C57BL/6J mouse model of obesity (2019) (45)
Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats (2010) (44)
Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance (2018) (44)
Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases (2018) (44)
TNF and other cytokines in the metabolism of septic shock and cachexia. (1992) (44)
HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors (2015) (44)
Bioelectronic Medicine: From Preclinical Studies on the Inflammatory Reflex to New Approaches in Disease Diagnosis and Treatment. (2019) (43)
TNF and Mae West or: death from too much of a good thing (1995) (43)
Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity (2011) (43)
Anti-HMGB 1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock (2006) (42)
VAGUS NERVE STIMULATION REGULATES HEMOSTASIS IN SWINE (2010) (42)
Regulating innate immunity with dopamine and electroacupuncture (2014) (42)
High Mobility Group B1 Protein Suppresses the Human Plasmacytoid Dendritic Cell Response to TLR9 Agonists1 (2006) (41)
Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493. (1998) (41)
Tumor necrosis factor in the malnutrition (cachexia) of infection and cancer. (1992) (41)
Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone (CNI-1493). (1997) (40)
Protein and substrate metabolism during starvation and parenteral refeeding. (1988) (39)
Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage (2005) (39)
Macrophage pacification reduces rodent pancreatitis‐induced hepatocellular injury through down‐regulation of hepatic tumor necrosis factor α and interleukin‐1β (1998) (39)
HMGB1 activates replication of latent HIV-1 in a monocytic cell-line, but inhibits HIV-1 replication in primary macrophages. (2006) (39)
Obesity Paradox, Obesity Orthodox, and the Metabolic Syndrome: An Approach to Unity (2016) (38)
Intracellular high mobility group B1 protein (HMGB1) represses HIV-1 LTR-directed transcription in a promoter- and cell-specific manner. (2003) (37)
Immune Cells Exploit a Neural Circuit to Enter the CNS (2012) (37)
Cachectin/TNF mediates the pathophysiological effects of bacterial endotoxin/lipopolysaccharide (LPS). (1988) (37)
Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex (2018) (37)
Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria (2013) (37)
Role of interleukin (IL)-2 receptor beta-chain subdomains and Shc in p38 mitogen-activated protein (MAP) kinase and p54 MAP kinase (stress-activated protein Kinase/c-Jun N-terminal kinase) activation. IL-2-driven proliferation is independent of p38 and p54 MAP kinase activation. (1999) (37)
A novel inhibitor of inflammatory cytokine production (CNI-1493) reduces rodent post-hemorrhagic vasospasm (2006) (36)
Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome. (1988) (36)
Pleiotropic effects of TNF in infection and neoplasia: beneficial, inflammatory, catabolic, or injurious. (1992) (36)
Spinal p38 MAP kinase regulates peripheral cholinergic outflow. (2008) (36)
Identification of Pigment Epithelium-Derived Factor as an Adipocyte-Derived Inflammatory Factor (2012) (35)
Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening (2013) (35)
Globin Attenuates the Innate Immune Response to Endotoxin (2002) (34)
Bioelectronic medicine: updates, challenges and paths forward (2019) (34)
Is Severe Sepsis a Neuroendocrine Disease? (2002) (34)
High mobility group box-1 as a therapeutic target downstream of tumor necrosis factor. (2003) (34)
Standardization of methods to record Vagus nerve activity in mice (2018) (33)
An Effective Method for Acute Vagus Nerve Stimulation in Experimental Inflammation (2019) (32)
High Mobility Group B1 Protein Suppresses the Human Plasmacytoid Dendritic Cell Response to TLR9 Agonists (2006) (32)
Physiological responses to cachectin. (1987) (31)
High mobility group box‐1 induces pro‐inflammatory signaling in human nucleus pulposus cells via toll‐like receptor 4‐dependent pathway (2018) (31)
Pathogenic role of HMGB1 in SARS? (2004) (31)
From mouse to man: or what have we learned about cytokine-based anti-inflammatory therapies? (1999) (31)
Sepsis defi nitions: time for change (2013) (29)
Ethyl Pyruvate Protects against Lethal Systemic Inflammation by Preventing HMGB1 Release (2003) (29)
Tolerance to shock: an exploration of mechanism. (1999) (29)
Mapping the immunological homunculus (2011) (29)
Prevention of lethality and suppression of proinflammatory cytokines in experimental septic shock by microencapsulated CNI-1493. (1999) (28)
Subacute Paraparesis Induced by Venous Thrombosis of a Spinal Angiolipoma: A Case Report (1997) (28)
Ancient Neurons Regulate Immunity (2011) (28)
Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Nonobese Diabetic Mice (2015) (27)
Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis* (2010) (27)
THE INFLAMMATORY REFLEX AND THE BRAIN: 598 (2004) (26)
Lethal Weight Loss: The Focus Shifts to Signal Transduction (2002) (26)
Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors (2015) (26)
Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity (2018) (26)
Specific vagus nerve stimulation parameters alter serum cytokine levels in the absence of inflammation (2020) (26)
Expression of Concern: The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation (2017) (25)
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation (2020) (24)
Identification of hypoglycemia-specific neural signals by decoding murine vagus nerve activity (2019) (24)
Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis (2019) (24)
Comparison of numerical and phenotypic leukocyte changes during constant hydrocortisone infusion in normal humans with those in thermally injured patients. (1987) (23)
Auricular neural stimulation as a new non-invasive treatment for opioid detoxification (2020) (23)
The tetravalent guanylhydrazone CNI-1493 blocks the toxic effects of interleukin-2 without diminishing antitumor efficacy. (1998) (23)
A New Approach to Rheumatoid Arthritis: Treating Inflammation with Computerized Nerve Stimulation (2012) (23)
CHAPTER 35 – Tumor necrosis factor (2003) (23)
RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury (2011) (22)
Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes (2015) (22)
Identification of tetranectin-targeting monoclonal antibodies to treat potentially lethal sepsis (2020) (22)
High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA2-IIE and sPLA2-V Expression in Macrophages (2016) (22)
Signet ring carcinoma of the pancreas, a rare variant with very high CEA values (1984) (22)
Cachectin: a pluripotent hormone released during the host response to invasion. (1987) (22)
Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19? (2020) (21)
The HIV Protease Inhibitor Saquinavir Inhibits HMGBl-Driven Inflammation by Targeting the Interaction of Cathepsin V with TLR4/MyD88 (2015) (21)
HYPOPHYSECTOMY, HIGH TUMOR NECROSIS FACTOR LEVELS, AND HEMOGLOBINEMIA IN LETHAL ENDOTOXEMIC SHOCK (1998) (21)
Role of Toll-like receptors 2 and 4, and the receptor for advanced glycation end products (RAGE) in HMGB1 induced inflammation in vivo (2010) (21)
Famotidine Use is Associated with Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Cohort Study (2020) (21)
HMGB1 released from nociceptors mediates inflammation (2021) (20)
The Cholinergic Drug Galantamine Alleviates Oxidative Stress Alongside Anti-inflammatory and Cardio-Metabolic Effects in Subjects With the Metabolic Syndrome in a Randomized Trial (2020) (20)
Aerobic Exercise Training and Inducible Inflammation: Results of a Randomized Controlled Trial in Healthy, Young Adults (2018) (20)
Approaching the next revolution? Evolutionary integration of neural and immune pathogen sensing and response. (2015) (19)
Human genetics: An inflammatory issue (2004) (19)
The pathophysiologic role of cachectin/TNF in septic shock and cachexia. (1988) (19)
Extremity amino acid metabolism during starvation and intravenous refeeding in humans. (1986) (19)
Therapeutic Targeting of High-Mobility Group Box-1 in Pulmonary Arterial Hypertension. (2019) (19)
Redox modifications of cysteine residues regulate the cytokine activity of HMGB1 (2021) (18)
HMGB 1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells (2014) (18)
Macrophage pacification reduces rodent pancreatitis-induced hepatocellular injury through down-regulation of hepatic tumor necrosis factor alpha and interleukin-1beta. (1998) (18)
Sequestering HMGB1 via DNA-Conjugated Beads Ameliorates Murine Colitis (2014) (18)
the systemic inflammatory response to endotoxin (2000) (17)
Development and characterization of a chronic implant mouse model for vagus nerve stimulation (2021) (17)
Targeted peripheral focused ultrasound stimulation attenuates obesity-induced metabolic and inflammatory dysfunctions (2021) (16)
New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (16)
CNI-1493 prolongs survival and reduces myocyte loss, apoptosis, and inflammation during rat cardiac allograft rejection. (1998) (16)
Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation (2021) (15)
Influence of enterectomy on peripheral tissue glutamine efflux in critically ill patients. (1990) (15)
Influence of substrate background on peripheral tissue responses to growth hormone. (1988) (15)
Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine (2022) (14)
Studies of Cachexia in Parasitic Infection (1989) (14)
CHAPTER 3 – Cholinergic Regulation of Inflammation (2007) (14)
Exercise-mediated peripheral tissue and whole-body amino acid metabolism during intravenous feeding in normal man. (1989) (14)
Green Tea Catechins Quench the Fluorescence of Bacteria-Conjugated Alexa Fluor Dyes (2013) (14)
CNI‐1493 ATTENUATES HEMODYNAMIC AND PRO‐INFLAMMATORY RESPONSES TO LPS (1998) (14)
Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons (2018) (13)
The influence of substrate background on the acute metabolic response to epinephrine and cortisol. (1991) (13)
Chronic systemic administration of tumor necrosis factor alpha and HIV gp120: effects on adult rodent brain and blood-brain barrier. (1999) (13)
Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. (2016) (13)
HMGB1 SIGNALS THROUGH TOLL‐LIKE RECEPTOR 2.: 40 (2004) (12)
The role of cachectin/tumor necrosis factor in AIDS. (1989) (12)
Tumour necrosis factor α (TNF) in neuroimmunology (1992) (12)
The effect of starvation and total parenteral nutrition on skeletal muscle amino acid content and membrane potential difference in normal man. (1988) (12)
Suppression of Macrophage Activation with CNI-1493 Increases Survival in Infant Rats with Systemic Haemophilus influenzae Infection (2000) (12)
Peripheral tissue metabolism in man with varied disease states and similar weight loss. (1986) (12)
High-performance liquid chromatographic method for guanylhydrazone compounds. (1996) (11)
Bioelectronic medicine: Preclinical insights and clinical advances (2022) (11)
Autonomous Expression of the slo Gene of the Bicistronic nga - slo Operon of Streptococcus pyogenes (2002) (11)
Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial (2022) (11)
Neurons Are the Inflammatory Problem (2018) (11)
Fatal Sequence: The Killer Within (2005) (11)
Peripheral Focused Ultrasound Stimulation (pFUS): New Competitor in Pharmaceutical Markets? (2019) (11)
Bacteria and the neural code. (2014) (10)
Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate (2010) (10)
Manipulation of the inflammatory reflex as a therapeutic strategy (2022) (10)
The Biology of Cachectin/Tumor Necrosis Factor (1990) (10)
Specific inhibition of macrophage-derived proinflammatory cytokine synthesis with a tetravalent guanylhydrazone CNI-1493 accelerates early islet graft function posttransplant. (1998) (10)
Buprenorphine Markedly Elevates a Panel of Surrogate Markers in a Murine Model of Sepsis (2019) (10)
Hypertension: an immune disorder? (2014) (9)
Vagus Nerve Stimulation Produces an Anti-Inflammatory Monocyte Phenotype in Blood. (2010) (9)
An impedance matching algorithm for common-mode interference removal in vagus nerve recordings (2020) (9)
Peripheral nerve stimulation and immunity: the expanding opportunities for providing mechanistic insight and therapeutic intervention. (2021) (9)
Lymphocyte called home: β2-adreneric neurotransmission confines T cells to lymph nodes to suppress inflammation (2014) (8)
IL-1 and IL-1 Are Endogenous Mediators Linking Cell Injury to the Adaptive Alloimmune Response (2007) (8)
A Phase I Clinical Trial of Tiopronin, a Putative Neuroprotective Agent, in Aneurysmal Subarachnoid Hemorrhage (2010) (8)
Submaximal Exercise During Intravenous Hyperalimentation of Depleted Subjects (1988) (7)
Specific vagus nerve stimulation parameters alter serum cytokine levels in the absence of inflammation (2020) (7)
Correction to: Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance (2018) (7)
Monoclonal Antibodies Capable of Binding SARS-CoV-2 Spike Protein Receptor Binding Motif Specifically Prevent GM-CSF Induction. (2020) (7)
Intravenous refeeding blocks growth hormone (GH)-provoked rises in serum free fatty acids and blunting of somatotroph response to GH-releasing hormone in normal men. (1989) (7)
Effect of starvation and total parenteral nutrition on electrolyte homeostasis in normal man. (1988) (6)
Tumor necrosis factor in metabolism of disease: hormonal actions versus local tissue effects. (1992) (6)
THE HMG B BOX CONFERS CYTOKINE ACTIVITY AND SIGNALS VIA RAGE.: 79 (2001) (6)
Sepsis definitions – Authors'reply (2013) (6)
The Revolutionary Future of Bioelectronic Medicine (2014) (6)
The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome (2021) (6)
CHAPTER 39 – HMGB-1 (2003) (6)
The gesture life of high mobility group box 1 (2003) (6)
Monoclonal antibodies capable of binding SARS‐CoV‐2 spike protein receptor‐binding motif specifically prevent GM‐CSF induction (2021) (5)
CHOLINE SUPPRESSES INFLAMMATORY RESPONSES (2006) (5)
Cachectin/tumor necrosis factor participates in reduction of skeletal muscle membrane potential: Evidence for bioactivity in plasma during critical illness (1986) (5)
MACROPHAGE PACIFICATION DECREASES PULMONARY TNF AND NO, ATTENUATING THE SEVERITY OF PANCREATITIS-INDUCED ARDS (1998) (5)
Organ- and Function-Specific Anatomical Organization and Bioelectronic Modulation of the Vagus Nerve (2022) (5)
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension (2021) (5)
Inhibition of HMGB 1 Enhances Bacterial Clearance and Protects against P . aeruginosa Pneumonia in Cystic Fibrosis (2012) (5)
318: Fetuin Protects Mice Against Lethal Sepsis by Modulating Bacterial Endotoxin-Induced HMGB1 Release and Autophagy (2009) (5)
Effect of hormonal and substrate backgrounds on cell membrane function in normal males. (1987) (5)
Suppressor αβ T Lymphocytes Control Innate Resistance to Endotoxic Shock (2005) (5)
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine: Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.C400018-JLR200an additional mechanism for its therapeutic effects in experimental sepsis (2005) (5)
Radioimmunoassay for methotrexate using hydroxyethylmethacrylate hydrogel (2004) (4)
Gifted hands: America’s most significant contributions to surgery (2010) (4)
Role of Interleukin (IL)-2 Receptor β-Chain Subdomains and Shc in p38 Mitogen-activated Protein (MAP) Kinase and p54 MAP Kinase (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Activation (1999) (4)
Erratum to: Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1) (2012) (4)
Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm (2022) (4)
Repairing the broken heart of dilated cardiomyopathy (1996) (4)
Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock. (2005) (4)
Possible inhibition of GM-CSF production by SARS-CoV-2 spike-based vaccines (2021) (4)
Toll-like receptor 4 (TLR4) and interferon-gamma (IFN-r) are required for HMGB1-induced TNF release from macrophages. (2010) (4)
Expression of Concern to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1) (2020) (3)
Hacking the inflammatory reflex (2021) (3)
Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1) (2020) (3)
HMGB1 PROMOTES NEUTROPHIL EXTRACELLULAR TRAP FORMATION (2013) (3)
HIV protease inhibitors saquinavir and nelfinavir are potent inhibitors of cathepsin L activity: A potential treatment for COVID-19 patients (2020) (3)
REVERSING ESTABLISHED SEPSIS WITH ANTAGO‐NIST OF HMGB1.: 271 (2003) (3)
Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm (2022) (3)
The monster within (2005) (3)
Transient Receptor Potential Ankyrin 1 Mediates Afferent Signals in the Inflammatory Reflex (2019) (3)
TNF-Dependent Mechanism Protein Release Partly Through a Induces High Mobility Group Box 1 γ IFN - (2003) (3)
Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes. (2018) (3)
Faculty Opinions recommendation of Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis. (2002) (3)
HIGH MOBILITY GROUP-1 (HMG-1) PROTEIN IS A MEDIATOR OF LETHAL ENDOTOXEMIA (1999) (3)
HMGB1 Mediates Persistent Splenocyte Priming in Sepsis Survivors: Evidence From a Murine Model. (2013) (3)
Long lasting macrophage cytokine suppression by alpha 7 nAChR requires JAK/STAT (138.23) (2010) (3)
The Fourth Bioelectronic Medicine Summit “Technology Targeting Molecular Mechanisms”: current progress, challenges, and charting the future (2021) (3)
Evidence of Long-range nerve pathways connecting and coordinating activity in secondary lymph organs (2020) (3)
CHOLINERGIC SUPPRESSION OF CYTOKINE RELEASE FROM HUMAN MACROPHAGES: 64 (2003) (3)
HMGB1 Is a Key Modulator Of Stress Erythropoiesis During Sepsis (2013) (3)
Antibody responses to immunization require sensory neurons (2019) (3)
Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice (2016) (2)
Exploring the vagus nerve and the inflammatory reflex for therapeutic benefit in chronic spinal cord injury (2022) (2)
kHz-frequency electrical stimulation selectively activates small, unmyelinated vagus afferents (2022) (2)
The Biochemical Basis of Cachexia of Infection (1990) (2)
Serum cytokine levels are modulated by specific frequencies, amplitudes, and pulse widths of vagus nerve stimulation (2020) (2)
Optogenetic stimulation of brain cholinergic networks suppresses inflammation (2016) (2)
MECHANICAL STIMULATION OF THE VAGUS NERVE IS SUFFICIENT FOR ACTIVATION OF THE CHOLINERGIC ANTI‐INFLAMMATORY PATHWAY IN MICE: 92 (2004) (2)
Tumor Necrosis Factor (Cachectin) in Septic/ Endotoxic Shock (2019) (2)
Optogenetic activation of fiber-specific compound action potentials in the mouse vagus nerve (2019) (2)
GALANTAMINE IMPROVES SURVIVAL IN LETHAL ENDOTOXEMIA (2006) (2)
From human to mouse and back offers hope for patients with fibromyalgia. (2021) (2)
DEVELOPMENT OF A SELECTIVE INHIBITOR OF CYTOKINE‐INDUCIBLE L‐ARGININE TRANSPORT (CNI‐1493) THAT BLOCKS MACROPHAGE PRODUCTION OF NO AND TNF&agr;, AND PROTECTS AGAINST LPS LETHALITY.: 31 (1995) (2)
Erratum: Lymphocyte-derived ACh regulates local innate but not adaptive immunity (Proceedings of the National Academy of Sciences of the United States of America (2013) 110 (1410-1415) DOI: 10.1073/pnas.1221655110) (2013) (2)
Selective electrical stimulation of vagus nerve induces specific cytokine response. (2018) (2)
Pigment epithelium-derived factor (PEDF) is an endogenous inflammatory factor (94.6) (2010) (2)
Response to “HMGB1 Mediates Cognitive Impairment in Sepsis Survivors” (2012) (2)
Cholinergic Stimulation Improves Hemostasis in a Hemophilia Mouse Model (2015) (2)
Oxidase Activation in Neutrophils: Role of Hemorrhagic Shock Induces NAD(P)H (2013) (2)
Thermogenic and nitrogen response to submaximal exercise in parenterally repleted normal man. (1987) (2)
endotoxin infusion in human volunteers: Assessment of the early cellular membrane response (1987) (2)
Improvement of the Adipokines Profile and Insulin Resistance in Metabolic Syndrome Patients Induced by Galantamine Activation of Cholinergic Pathway (2016) (1)
Vagus Nerve Stimulation: A Potential Therapeutic Role in Childhood Nephrotic Syndrome? (2022) (1)
MACROPHAGE INHIBITION ATTENUATES PROTECTIVE EFFECTS OF SUBLETHAL HEMORRHAGE IN LPS CHALLENGED RATS: 56 (1998) (1)
Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival (2022) (1)
VAGUS NERVE STIMULATION IMPROVES SURVIVAL IN EXPERIMENTAL SEPSIS.: 118-T (2005) (1)
Intermittent KHz-frequency electrical stimulation selectively engages small unmyelinated vagal afferents (2022) (1)
Human Dermcidin Protects Mice Against Hepatic Ischemia-Reperfusion–Induced Local and Remote Inflammatory Injury (2022) (1)
VAGUS NERVE STIMULATION ATTENUATES CARDIAC TNF PRODUCTION IN ENDOTOXIC SHOCK.: 81 (2001) (1)
Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation (2019) (1)
Role of Tumor Necrosis Factor in Protein Metabolism (2006) (1)
ADMINISTRATION OF ADRENOMEDULLIN (AM) AND AM BINDING PROTEIN‐1 (AMBP‐1) IN HEMORRHAGE ATTENUATES TISSUE INJURY AND DECREASES SERUM TNF‐&agr; AND HMGB1.: 122 (2004) (1)
INTRACEREBROVENTRICULAR CNI‐1493 PREVENTS LPS‐INDUCED HYPOTENSION AND PEAK SERUM TNF AT A FOUR‐LOG LOWER DOSE THAN SYSTEMIC TREATMENT.: 86 (1998) (1)
The pro-inflammatory effect of HMGB1, a mediator of inflammation in arthritis, is dependent on the redox status of the protein (2012) (1)
HMGB1 impairs erythropoiesis during sepsis (P3163) (2013) (1)
Alarmin HMGB 1 in Endotoxemia Inflammasome-Dependent Release of the Dixit (2010) (1)
Identification of emetine as a therapeutic agent that targets pigment epithelium derived factor - mediated inflammation and improves hyperglycemia in murine models of type 1 diabetes (IRM9P.728) (2014) (1)
Removal of HMGB1 in inflammatory bowel disease using DNA-beads. (P5197) (2013) (1)
318 Central Muscarinic 1 Acetylcholine Receptor Activation Reduces the Severity of Experimental Colitis via the Splenic Nerve and the Spleen (2013) (1)
Inhibition of Human Erythropoiesis during Inflammation Is Mediated By High Mobility Group Box Protein 1 (HMGB1) through Decreased Commitment of Hematopoietic Stem Cells to the Erythroid Lineage and By Increased Apoptosis of Terminally Differentiating Erythroblasts (2016) (1)
HEMOGLOBIN ENHANCES MIF-AND INTERLEUKIN-1-MEDIATED TNF RELEASE IN MURINE MACROPHAGE-LIKE RAW 264.7 CELLS (1999) (1)
Oxytocin and Related Peptide Hormones: Candidate Anti-Inflammatory Therapy in Early Stages of Sepsis (2022) (1)
CD11b Down-Regulate Leukocyte Trafficking via Cholinergic Neural Signals to the Spleen (2009) (1)
110 Modulation of the Inflammatory Response. (2012) (1)
First-in-human demonstration of splenic ultrasound stimulation for non-invasively controlling inflammation (2020) (1)
MIF PHARMACOLOGICAL INHIBITION PROTECTS IN ENDOTOXEMIA AND SEPSIS: 226 (2004) (1)
Splenectomy improves survival in experimental polymicrobial sepsis (2006) (1)
TUMOR NECROSIS FACTOR, OTHER CYTOKINES AND (1993) (1)
Author Correction: Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation (2020) (1)
Selective alpha7 nicotinic receptor activation improves survival in murine sepsis (2006) (1)
Vagus Nerve Stimulation Produces an Anti-Inflammatory Monocyte Phenotype in Blood. (138.25) (2010) (1)
Erratum: Understanding immunity requires more than immunology (2010) (1)
High Mobility Group Box‐1 Protein (hmgb1) Is Increased in Anca‐associated Vasculitis (aav) with Renal Manifestations (1)
ETHYL PYRUVATE PREVENTS ENDOTOXIN LETHALITY.: 118 (2001) (1)
Macrophage-Deactivating Agent Autoimmune Encephalomyelitis by CNI-1493 , a Prevention and Treatment of Experimental (1998) (1)
Identification of cytokine-specific sensory neural signals in murine vagus nerve activity recordings (2018) (1)
Cholinergic signaling in the dorsal motor nucleus regulates systemic inflammatory responses via the vagus nerve (2018) (1)
HMGB-1: an inflammatory mediator in MPTP induced neuronal damage (2010) (1)
Neural control of acetylcholine release by T cells attenuates TNF production in endotoxemia (138.24) (2010) (1)
Polyamine Oxidase and 3-Aminopropanal in the Pathogenesis of Cerebral Ischemia (2002) (1)
Circulating HMGB1 is increased in myelodysplastic syndrome but not in other bone marrow failure syndromes: proof-of-concept cross-sectional study (2022) (1)
7 – Cachectin–TNF in the Biology of Disease (1991) (1)
Regulation of HMGB1 release by inflammasomes (2013) (1)
CHOLINERGIC AGONISTS INHIBIT TNF PRODUCTION BY SPLEEN MACROPHAGES IN A MOUSE MODEL OF LETHAL ENDOTOXEMIA (2006) (1)
Vagus nerve stimulation using clinically approved parameters suppresses TNF production in endotoxemic mice (2004) (1)
NICOTINE INHIBITS THE RELEASE OF HMGB1 THROUGH POST‐TRANSLATIONAL MECHANISM.: 188 (2002) (1)
49: OPTOGENETIC STIMULATION OF DMV CHOLINERGIC NEURONS INHIBITS SERUM CYTOKINES IN ENDOTOXEMIA (2019) (1)
MONOCLONAL HMGB1 ANTIBODIES PROTECT AGAINST SEPSIS LETHALITY IN MICE: 509 (2004) (1)
Endothelial Biomedicine: Brain Endothelial Cells Bridge Neural and Immune Networks (2007) (0)
Haptoglobin inhibits the pro-inflammatory activity of HMGB1. (172.19) (2012) (0)
Ethanol blocks leukocyte recruitment and endothelial cell activation: 241 (2004) (0)
Choline acetyltransferase attenuates inflammation in a murine model of DSS colitis and sepsis (2022) (0)
Symposium: The Merinoff World Congress 2013: HMGB1 (2014) (0)
Choline Acetyltransferase Administration Decrease Blood Pressure in a Murine Model of Hypertension (2021) (0)
C1q-based tolerance mechanism in HMGB1-mediated activation of human monocytes (IRM5P.649) (2015) (0)
CNI‐1493 PROTECTION FROM LPS‐INDUCED GUT INJURY.: 105 (1998) (0)
Identification of hypoglycemia-specific neural signals by decoding murine vagus nerve activity (2019) (0)
Haptoglobin inhibits the pro-inflammatory activity of HMGB1 (P4177) (2013) (0)
Transient Receptor Potential Ankyrin 1 Mediates the Afferent Arm of the Inflammatory Reflex (2018) (0)
The Role of Sensory Nerves in Modulating Antigen Specific Immune Responses (2019) (0)
Anti‐Inflammatory Effects of Famotidine (2021) (0)
Spermine inhibition of HMG1 activity (2000) (0)
Identification of hemopexin as an anti-inflammatory factor that inhibits hemoglobin synergy with HMGB1 in sterile and infectious inflammation (172.11) (2012) (0)
TRPV1+ Neurons are Required for Antigen‐Specific Immune Responses (2021) (0)
FETUIN, A UBIQUITOUS SERUM PROTEIN, INHIBITS EDEMA FORMATION AND TNF (1999) (0)
the Human Plasmacytoid Dendritic Cell High Mobility Group B1 Protein Suppresses (2013) (0)
CENTRALLY ACTING ACETYLCHOLINESTERASE INHIBITORS IMPROVE SURVIVAL IN A MURINE MODEL OF SEPSIS: 105 (2004) (0)
78 – Research Methods in Neurosurgery (2001) (0)
Introduction: Electronic Medicine in Immunology Special Issue Part 2 (2021) (0)
Galantamine Treatment as a Novel Therapeutic Approach in Alleviating Obesity and Obesity-Related Complications in High-Fat Diet-Fed Mice: 287 (2010) (0)
Vagus Nerve Stimulation and Brainstem Cholinergic Neurons Modulate Experimental Pancreatitis Severity (2021) (0)
876 Pharmacological Central Activation of the Vagus Nerve Reduces Experimental Colitis (2012) (0)
High Intensity Focus Ultrasound Stimulation of Spleen Reduces Traumatic Bleeding in Mice (2022) (0)
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension (2021) (0)
NUCLEAR HMGB1 TRANSLOCATION IS ESSENTIAL FOR ITS ACTIVE RELEASE BY ACTIVATED MACROPHAGE/MONOCYTE.: 62 (2003) (0)
HMGB1 mediates Splenomegaly, Anemia and Leukocytosis in Mice Surviving Sepsis (44.7) (2012) (0)
High Intensity Focused Ultrasound Treatment Attenuates Disease Progression in a Mouse Model of Non‐Alcoholic Steatohepatitis (2019) (0)
SUPPRESSION OF HMG‐1 RELEASE BY A MACROPHAGE‐DEACTIVATING AGENT, CNI‐1493.: 71 (2001) (0)
MONOCLONAL HMGB1 ANTIBODIES PROTECT AGAINST SEPSIS LETHALITY IN MICE.: 8 (2004) (0)
Auricular neural stimulation as a new non-invasive treatment for opioid detoxification (2020) (0)
Antagonists of HMG1 for the treatment of inflammatory conditions (2000) (0)
A dual tracer [11C]PBR28 and [18F]FDG microPET evaluation of neuroinflammation and brain energy metabolism in murine endotoxemia (2022) (0)
THE CHOLINERGIC ANTI‐INFLAMMATORY PATHWAY FROM THE BRAIN TO THE SERUM.: 46 (2004) (0)
O.46 A newly synthesized inhibitor of proinflammatorycytokines (CNI-1493), prevents increased ureagenesis and development of negative nitrogen balance in a murine model of cancer-associated wasting (1997) (0)
Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases (2018) (0)
SERUM LEVELS OF THE PRO‐INFLAMMATORY CYTOKINE HMGB1 CORRELATE WITH VAGUS NERVE ACTIVITY: 157 (2004) (0)
Activation of dorsal motor nucleus cholinergic neurons ameliorates the severity of acute pancreatitis (2022) (0)
The Acetylcholinesterase Inhibitor Galantamine Ameliorates Oxidative Stress in Subjects with the Metabolic Syndrome (2020) (0)
Standardization of methods to record Vagus nerve activity in mice (2018) (0)
Molecular Medicine Commemorates the Career and Science of Anthony Cerami (2014) (0)
Focused Ultrasound Modulation of Hepatic Neural Plexus Restores Glucose Homeostasis in Diabetes (2021) (0)
Detection of a novel cytokine in wound chambers by the polymerase chain reaction (1989) (0)
Hyperoxia Causes Cell Cycle Arrest In Macrophages (AM) And Reduces Polymorphonuclear Leukocyte (PMN) Uptake.: 258 (2003) (0)
VAGUS NERVE STIMULATION ATTENUATES BLEEDING IN A RODENT TAIL TRANSECTION MODEL.: 208 (2004) (0)
7th Key Symposium Molecular Basis of Applied Biological Therapeutics (2011) (0)
Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation (2019) (0)
Bioelectronic medicine: updates, challenges and paths forward (2019) (0)
Vagus Nerve Stimulation Accelerates Thrombosis via α7 Nicotinic Acetylcholine Receptors and Improves Clot Formation in Hemophilia A Mice (2022) (0)
Vagus Nerve Sensory Neurons Respond Distinctly to Specific Inflammatory Mediators (2022) (0)
Treatment of type 1 diabetes by {alpha}7nAChR pathway activation. (2012) (0)
A NEGATIVE ACUTE PHASE PROTEIN, FETUIN, INHIBITS HMGB1 RELEASE, AND PROTECTS MICE AGAINST LETHAL ENDOTOXEMIA.: 5 (2004) (0)
and Reduces Serum HMGB1 Levels Splenectomy Protects against Sepsis Lethality (2008) (0)
Epidermal Growth Factor VIII Rescue Septic Animals Via Milk Fat Globule Immature Dendritic Cell-Derived Exosomes (2009) (0)
Treatment of Established Lethal Peritonitis by Delayed Administration Of Ethyl Pyruvate: 155 (2002) (0)
Sa1641: NON-INVASIVE VAGAL NERVE STIMULATION TO TREAT CROHN DISEASE AND ULCERATIVE COLITIS IN CHILDREN AND YOUNG ADULTS (2022) (0)
HMGB1 is a key mediator of anemia in a murine model of sepsis survivors (CCR3P.224) (2014) (0)
High-frequency electrical stimulation attenuates neuronal release of inflammatory mediators and ameliorates neuropathic pain (2022) (0)
List of Contributors and Discussants (1981) (0)
Protective Effects of Pegylated Choline Acetyltransferase in a Murine Model of DSS Colitis (2022) (0)
Vagus Nerve Stimulation Attenuates Peripheral Hemorrhage In Rodents And Swine (2006) (0)
Calcium imaging and analysis of the jugular-nodose ganglia enables identification of distinct vagal sensory neuron subsets (2023) (0)
Sterile and Infectious Inflammation Synergy of Hemoglobin with HMGB1 in Anti-inflammatory Factor That Inhibits Identification of Hemopexin as an (2012) (0)
Optogenetic Stimulation of Cholinergic Neurons in the Brainstem Induces Splenic Nerve Activity and Attenuates Systemic Inflammation (2019) (0)
Suppression of Macrophage Activation with CNI-1493 Increases Survival in Infant Rats with Systemic Haemophilus influenzae Infection (2002) (0)
VAGOTOMY BLOCKS THE PROTECTIVE EFFECTS OF I.C.V. CNI-1493 AGAINST LPS-INDUCED SHOCK (1999) (0)
PMNS EXACERBATE HYPEROXIC LUNG INJURY VIA AUGMENTED ALVEOLAR EPITHELIAL CELL DEATH.: 78 (2004) (0)
Abstract S04-01: Famotidine use and quantitative symptom tracking for COVID-19 in nonhospitalized patients: A case series (2020) (0)
Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival (2022) (0)
Anti-HMGB1 Antibodies and Alpha-7 Agonists as Experimental Therapeutics as BW Countermeasures (2006) (0)
Toll-like Receptor 2 Modulates Left Ventricular Function Following Ischemia-Reperfusion Injury Running Head : TLR 2 and ischemia-reperfusion injury (2006) (0)
Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity (2018) (0)
Author response: Development and characterization of a chronic implant mouse model for vagus nerve stimulation (2021) (0)
Sequestering HMGB1 using DNA-conjugated beads ameliorates murine colitis (THER5P.840) (2014) (0)
New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut (2017) (0)
PKR is an essential regulator of HMGB1 release (116.38) (2011) (0)
RECOMBINANT HMG‐1 “B‐BOX” INCREASES THE PERMEABILITY OF CACO‐2 ENTEROCYTIC MONOLAYERS VIA A RAGE‐DEPENDENT MECHANISM: 103 (2001) (0)
Novel Role of Cathepsin V in TLR4 Mediated Signaling (2014) (0)
Guanylhydrazones for the treatment of inflammatory conditions. (1995) (0)
formation through interactions with Toll-like receptor 4 HMGB1 promotes neutrophil extracellular trap (2013) (0)
The Cholinergic Drug Galantamine Ameliorates Acute Respiratory Distress Syndrome in Mice (2022) (0)
In a murine model of sepsis, IL-6 increases early and remains high until week 4, when its decrease may be related to late-phase immunodeficiency. (117.27) (2011) (0)
Endotoxin and Cancer (2020) (0)
Toll-like receptor 4 (TLR4) and interferon-gamma (IFN-r) are required for HMGB1-induced TNF release from macrophages. (34.18) (2010) (0)
P072 Non-invasive Vagal Nerve Stimulation to Treat Crohn Disease and Ulcerative Colitis in Children and Young Adults: A Proof-of-Concept Clinical Trial (2021) (0)
Vagus nerve sensory neurons have distinct neural responses to inflammatory mediators (2022) (0)
Maturation and Th1 Polarization Endogenous Signal for Dendritic Cell High Mobility Group Box Protein 1: An (2004) (0)
Neuroinflammation in Murine Endotoxemia: A Dual‐Tracer MicroPET Evaluation (2020) (0)
Choline Acetyltransferase-Expressing T cells are rare in young mice (122.7) (2012) (0)
Treatment of type 1 diabetes by α7nAChR pathway activation. (51.11) (2012) (0)
Correction to: Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance (2018) (0)
Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear (2019) (0)
New Insight into the Vagus Nerve Regulation of Glucose Homeostasis: A Role for Afferent Signaling and Skeletal Muscle Glucose Uptake (2021) (0)
The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the circulation (2020) (0)
CNI-1493 prevents induction of endotoxin tolerance by LPS pretreatment in RAW264.7 macrophages (2000) (0)
HIGH MOBILITY GROUP BOX 1 (HMGBl) PROTEIN DELAYS APOPTOSIS IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES (PMN): 138 (2002) (0)
Cholinergic activation by galantamine suppresses obesity-associated inflammation in mice (54.4) (2011) (0)
Evidence of Long-range nerve pathways connecting and coordinating activity in secondary lymph organs (2020) (0)
Thiocarbazate building blocks enable the construction of azapeptides for rapid development of therapeutic candidates (2022) (0)
INSULIN ATTENUATES THE SYSTEMIC INFLAMMATORY RESPONSE DURING ENDOTOXEMIA: 520 (2004) (0)
Author Correction: Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation (2020) (0)
Pigment epithelium-derived factor as an inflammatory factor -- a new role for an old protein (2011) (0)
HMGB1 Expression in Sickle Cell Disease: A Pro-Inflammatory Cytokine and Potential Therapeutic Target. (2007) (0)
Cholinergic neuronal signals attenuate inflammasome activation through inhibiting mitochondrial stress (P1264) (2013) (0)
Microenvironment and Immunology HMGB 1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells (2014) (0)
OR.28. Macrophages Remember Neural Signals that Teach Attenuation of Responses to Bacterial Endotoxin (2008) (0)
Preservation of functional aerobic capacity with daily submaximal exercise during intravenous feeding in hospitalized normal man (1988) (0)
Serum levels of the pro-inflammatory cytokine HMGB1 correlate with vagus nerve activity in patients with abdominal aortic aneurysms (2004) (0)
Basal forebrain cholinergic signaling regulates peripheral cytokine responses (INC1P.349) (2015) (0)
LETHAL ENDOTOXEMIA FROM TNF TO HMG-1.: 171 (1999) (0)
Introduction: Electronic Medicine in Immunology Special Issue Part 1 (2021) (0)
HMG1 antagonists for the treatment of inflammatory conditions (2000) (0)
Positive allosteric modulation of M1 muscarinic acetylcholine receptors suppresses lethal peripheral inflammation (P5082) (2013) (0)
Identification of procathepsin L (pCTS-L)–neutralizing monoclonal antibodies to treat potentially lethal sepsis (2023) (0)
All-Thiol HMGB1 Is a Critical Inducer of Anemia in Sepsis Survivors through CXCR4 Signaling (2014) (0)
alpha7 nicotinic acetylcholine receptor and cAMP response element binding protein are essential for prolonged monocyte deactivation by vagus nerve signaling (116.37) (2011) (0)
HEPATIC INJURY AND SYSTEMIC INFLAMMATION AFTER TRAUMA REQUIRES TLR4 AND IS MEDIATED BY HMGB1 (2006) (0)
ACETYLCHOLINE INHIBITS ENDOTHELIAL CELL ACTIVATION IN VITRO: 237 (2003) (0)
Libraries: Steamboat Campus Library: BIO 216 - Human Pathophysiology (2012) (0)
&agr;‐CHEMOKINE RECEPTOR INHIBITOR REDUCES HMGB‐1 INDUCED ACUTE LUNG INJURY.: 270 (2003) (0)
Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria (2013) (0)
Composes anti-inflammatoires (2004) (0)
Guanylhydrazones useful in the treatment of diseases associated with the activation of T cells. (1997) (0)
WHAT'S NEW IN SHOCK, MAY 2010? (2010) (0)
Immunization elicits antigen-specific antibody sequestration in sensory neurons (2018) (0)
Suppression of Macrophage Activation with CNI-1493 Increases Survival in Infant Rats with Systemic Infection. (2002) (0)
Biologically active versus immunoreactive high-mobility group box 1 (2007) (0)
High-mobility group box 1 inhibition protects against hepatic ischemia-reperfusion injury (2004) (0)
Libraries: Steamboat Campus Library: The Library's Tower Garden (2012) (0)
Redox modifications of cysteine residues regulate the cytokine activity of HMGB1 (2021) (0)
Induction of Pro‐Inflammatory Cytokines TNF, IL‐6, and HMGB1 by SARS‐CoV‐2 Spike Proteins in Mice and in Murine Macrophage Cultures (2021) (0)
Famotidine exerts anti‐inflammatory effects via a vagus nerve‐dependent mechanism (2022) (0)
Selective Optogenetic Activation of the Inflammatory Reflex Using Multisite Surgical Approach (2018) (0)
Cholinergic Agonists Inhibit LPS Induced Whole Blood TNF Release Ex Vivo In Patients With Severe Sepsis: A Pilot Study (2007) (0)
High mobility group box-1 (HMGB1) preconditioning protects against hepatic ischemia reperfusion injury (2006) (0)
Abstract 461: Inhibition of HMGB1 delays tumor progression, reduces MDSC-mediated immune suppression, and diminishes MDSC-macrophage cross-talk interaction. (2013) (0)
Nerves and immunity: reflexes in immunological homeostasis (84.2) (2014) (0)
Inflammasome-Dependent Release of the Dixit (2010) (0)
400 The Kinetics of High Mobility Group Box-1 During Acute Coronary Syndromes (2012) (0)
Synergy of Hemoglobin with HMGB 1 in Anti-Inflammatory Factor That Inhibits Identification of Hemopexin as an Shaw (2012) (0)
Focused ultrasound neuromodulation of the spleen activates an anti-inflammatory response in humans (2023) (0)
Symposium (2009) (0)
The Fourth Bioelectronic Medicine Summit “Technology Targeting Molecular Mechanisms”: current progress, challenges, and charting the future (2021) (0)
NICOTINE ATTENUATES LPS‐INDUCED RELEASE OF HMG‐1, A LATE MEDIATOR OF ENDOTOXEMIA.: 119 (2001) (0)
Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance (2018) (0)
T Cell Subpopulations Following Thermal Injury Effect of the Acute Stress Response (1987) (0)
The HMGB1-MD-2 axis as a novel therapeutic target in inflammatory diseases (CCR5P.210) (2015) (0)
Cervical vagotomy aggravates experimental pancreatitis severity in mice (2003) (0)
ANTI‐HMGB1 ANTIBODIES PROTECT AGAINST SEPSIS LETHALITY IN MICE.: 2 (2002) (0)
Cholinergic signaling in the forebrain regulates peripheral inflammation (2017) (0)
Identification of the brain network controlling systemic inflammatory signals (2022) (0)
High frequency electrical stimulation reduces neuronal HMGB1 release (2022) (0)
Late-Acting Proinflammatory Mediator, High Lethal Sepsis by Selectively Attenuating a A Cardiovascular Drug Rescues Mice from (2007) (0)
ANTIINFLAMMATORY ROLE OF CENTRAL MUSCARINIC ACETYLCHOLINE RECEPTORS.: 190 (2003) (0)
HMGBI AS A LATE MEDIATOR AND THERAPEUTIC TARGET IN SEPSIS: 493 (2004) (0)
CHOLINERGIC ACTIVATION OF ENDOTHELIAL CELL ACTIVATION IN VITRO AND IN VIVO BY NICOTINE: 238 (2004) (0)
Guanylhydrazones useful for treatment of conditions associated with t-cell diseases (1997) (0)
Calcium imaging of the nodose ganglion reveals specific cell responses to specific cytokines (2021) (0)
ANTI-HMGB1 BUT NOT SOLUBLE RAGE AS THERAPEUTIC INTERVENTION IN EXPERIMENTAL RENAL ISCHEMIA/REPERFUSION-INDUCED INJURY: 1116 (2010) (0)
HMGB1 expression in hormonally independent breast carcinoma (2008) (0)
Libraries: Steamboat Campus Library: GEO 106 - Human Geography (2012) (0)
Optogenetic stimulation of cholinergic neuronal endings in the celiac‐superior mesenteric ganglion complex suppresses inflammation in murine endotoxemia (2022) (0)
The deleterious effects of High Mobility Group Box 1 in the MPTP model and Parkinson's disease can be attenuated by glycyrrhizin (2014) (0)
HMGB1 Causes Anemia of Inflammation By Modulating Erythropoietin Signal Transduction (2018) (0)
Neural circuitry and immunity (2015) (0)
Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1) (2020) (0)
The M1 muscarinic acetylcholine receptor agonist xanomeline suppresses lethal inflammation (2009) (0)
Inhibition of HMGB1 delays tumor progression, reduces MDSC-mediated immune suppression, and diminishes MDSC-macrophage cross-talk (P2001) (2013) (0)
Guanylhydrazone to treat inflammation (1995) (0)
Transient Receptor Potential Ankyrin 1 (TRPA1) mediates IL-1β-Induced Thermoregulation (2022) (0)
3-aminopropanal in the pathogenesis of ischemia (2000) (0)
IL‐1β‐Induced Thermoregulation and Vagus Nerve Activity is Mediated by Transient Receptor Potential Ankyrin 1 (2021) (0)
Choline acetyltransferase+ T cells represent a discrete lymphocyte subset that regulates innate immunity. (P1008) (2013) (0)
Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis (2019) (0)
PKR is required for NLRP3 inflammasome activation and HMGB1 release (114.7) (2012) (0)
ALCOHOL AND ITS METABOLITE BLOCK ENDOTHELIAL CELL ACTIVATION AND COAGULANT ACTIVITY: 5 (2003) (0)
Cachectin/TNF: A Mediator of Lethal Endotoxemia (1987) (0)
Possible inhibition of GM-CSF production by SARS-CoV-2 spike-based vaccines (2021) (0)
The Cholinergic Anti-inflammatory Pathway: Connecting the Mind and Body (2007) (0)
Optogenetic stimulation of the brainstem dorsal motor nucleus ameliorates acute pancreatitis (2023) (0)
Choline acetyltransferase+ lymphocytes regulate endothelial nitric oxide synthase (MUC2P.939) (2015) (0)
Neural Regulation of Cytokines (2009) (0)
RESULTS Galantamine Reduces Body Weight Gain , Food Intake and Abdominal Adiposity in High-Fat Diet – Fed Mice (2011) (0)
Preservation of pysiologic parameters during experimental pancreatitis by macrophage pacification (1998) (0)
Serum-Free Hemoglobin Increases Tumor Necrosis Factor Synthesis and Lipopolysaccharide Lethality (2002) (0)
for disulfide HMGB1– dependent TLR4 signaling (2015) (0)
Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII (2009) (0)
Electrical Stimulation of the Dorsal Motor Nucleus of the Vagus Attenuates Serum Pro‐Inflammatory Cytokine Levels in Murine Models of Endotoxemia and Sepsis (2022) (0)
Pigment epithelium-derived factor as an inflammatory factor — a new role for an old protein (60.4) (2011) (0)
Organ- and function-specific anatomical organization of vagal fibers supports fascicular vagus nerve stimulation (2023) (0)
Expression of Concern to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1) (2020) (0)
Organ- and function-specific anatomical organization of the vagus nerve (2022) (0)
Farewell Statement from Dr. Cerami and Dr. Tracey as Outgoing Co-Editors in Chief of Molecular Medicine (2014) (0)

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