Khalid Iqbal

Khalid Iqbal's AcademicInfluence.com Rankings

Khalid Iqbal

Biology

#4260

World Rank

#6379

Historical Rank

Neuroscience

#438

World Rank

#457

Historical Rank

biology Degrees

Download Badge

Biology

Khalid Iqbal's Degrees

PhD Neuroscience Stanford University
Masters Biology University of California, Berkeley

Similar Degrees You Can Earn

Best Online Master's in Biology

Why Is Khalid Iqbal Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Khalid Iqbal's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. (1986) (3176)
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. (1986) (1628)
Defeating Alzheimer's disease and other dementias: a priority for European science and society (2016) (1172)
Tau pathology in Alzheimer disease and other tauopathies. (2005) (937)
Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments (2001) (870)
Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease (1989) (787)
Tau in Alzheimer disease and related tauopathies. (2010) (783)
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules (1996) (772)
Improved discrimination of AD patients using β-amyloid(1-42) and tau levels in CSF (1999) (716)
Abnormal phosphorylation of the microtubule-associated protein? (tau) in Alzheimer cytoskeletal pathology (1987) (705)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation (2005) (692)
Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. (1994) (671)
Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. (1993) (650)
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. (2004) (642)
Mechanisms of tau-induced neurodegeneration (2009) (591)
Tau and neurodegenerative disease: the story so far (2016) (547)
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration (2007) (504)
Phosphoprotein Phosphatase Activities in Alzheimer Disease Brain (1993) (503)
Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. (2008) (468)
Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. (1993) (460)
Phosphatase Activity Toward Abnormally Phosphorylated τ: Decrease in Alzheimer Disease Brain (1995) (446)
Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes (2011) (428)
Distribution of Active Glycogen Synthase Kinase 3β (GSK-3β) in Brains Staged for Alzheimer Disease Neurofibrillary Changes (1999) (428)
Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques (1986) (423)
Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. (2012) (420)
Post-translational modifications of tau protein in Alzheimer’s disease (2005) (417)
Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau. (1997) (414)
Phosphorylation of Microtubule-associated Protein Tau Is Regulated by Protein Phosphatase 2A in Mammalian Brain (2000) (407)
DEFECTIVE BRAIN MICROTUBULE ASSEMBLY IN ALZHEIMER'S DISEASE (1986) (393)
The Alzheimer’s Association external quality control program for cerebrospinal fluid biomarkers (2011) (385)
Distribution, Levels, and Activity of Glycogen Synthase Kinase‐3 in the Alzheimer Disease Brain (1997) (344)
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. (2009) (326)
Brain Levels of Microtubule‐Associated Protein τ Are Elevated in Alzheimer's Disease: A Radioimmuno‐Slot‐Blot Assay for Nanograms of the Protein (1992) (310)
Glycosylation of microtubule–associated protein tau: An abnormal posttranslational modification in Alzheimer's disease (1996) (309)
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease (2008) (305)
Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. (1998) (298)
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. (2003) (279)
Promotion of Hyperphosphorylation by Frontotemporal Dementia Tau Mutations* (2004) (277)
Brain aluminum in aging and Alzheimer disease (1979) (273)
Dephosphorylation of Alzheimer Paired Helical Filaments by Protein Phosphatase-2A and −2B (*) (1995) (266)
Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease. (1989) (246)
Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention (2007) (233)
Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus (2008) (231)
Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration (1998) (223)
Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. (2009) (219)
Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. (2002) (218)
Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes. (1999) (217)
A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse) (2013) (213)
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. (2005) (210)
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome (2008) (203)
Down syndrome and Alzheimer's disease: Common pathways, common goals (2015) (195)
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce β-amyloid fibrils (2004) (188)
Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease (1991) (186)
Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity. (2006) (185)
Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay. (2002) (181)
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK‐3β (2002) (179)
Role of protein phosphatase‐2A and ‐1 in the regulation of GSK‐3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain (2000) (179)
Alzheimer's disease, a multifactorial disorder seeking multitherapies (2010) (178)
Site‐specific effects of tau phosphorylation on its microtubule assembly activity and self‐aggregation (2007) (177)
Alzheimer's disease : biology, diagnosis, and therapeutics (1996) (174)
Phosphorylation of Tau at Thr212, Thr231, and Ser262 Combined Causes Neurodegeneration* (2010) (172)
Abnormal fibrils from scrapie-infected brain (2004) (171)
Truncation and Activation of Calcineurin A by Calpain I in Alzheimer Disease Brain* (2005) (169)
Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia (2004) (169)
Tau Becomes a More Favorable Substrate for GSK-3 When It Is Prephosphorylated by PKA in Rat Brain* (2004) (167)
Alzheimer paired helical filaments Restoration of the biological activity by dephosphorylation (1994) (167)
Brain glucose transporters, O‐GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease (2009) (166)
Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains (1994) (164)
Role of protein kinase B in Alzheimer's neurofibrillary pathology (2003) (164)
Histopathological criteria for progressive dementia disorders: clinical-pathological correlation and classification by multivariate data analysis (2004) (164)
Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers (2005) (163)
Alzheimer's disease : basic mechanisms, diagnosis and therapeutic strategies (1991) (160)
Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1. (1996) (159)
Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. (2001) (159)
Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein. (2001) (158)
Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A (1994) (157)
PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta. (2010) (155)
Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau (2007) (155)
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration (2004) (154)
Research advances in Alzheimer's disease and related disorders (1995) (151)
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases (2009) (148)
An Antigenic Profile of Lewy Bodies: Immunocytochemical Indication for Protein Phosphorylation and Ubiquitination (1989) (148)
Alzheimer's Disease Abnormally Phosphorylated τ Is Dephosphorylated by Protein Phosphatase‐2B (Calcineurin) (1994) (146)
Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome*♦ (2008) (146)
Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease. (1989) (143)
Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. (2003) (141)
Detection of point mutations in codon 331 of mitochondrial NADH dehydrogenase subunit 2 in Alzheimer's brains. (1992) (139)
Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease (2002) (137)
Dephosphorylation of Tau by Protein Phosphatase 5 (2005) (133)
Alzheimer's disease and related disorders. (1986) (132)
STALOSYLGALACTOSYL CERAMTDE AS A SPECIFIC MARKER FOR HUMAN MYELIN AND OLIGODENDROGLIAL PERIKARYA: GANGLIOSIDES OF HUMAN MYELIN, OLIGODENDROGLIA AND NEURONS (1979) (130)
Lewy Bodies Contain Epitopes Both Shared and Distinct from Alzheimer Neurofibrillary Tangles (1988) (130)
Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles. (1998) (129)
Microtubule-associated polypeptides tau are altered in Alzheimer paired helical filaments. (1988) (129)
Dephosphorylation of microtubule‐associated protein tau by protein phosphatase‐1 and ‐2C and its implication in Alzheimer disease (1994) (128)
Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5 (1997) (127)
Hyperphosphorylation and accumulation of neurofilament proteins in Alzheimer disease brain and in okadaic acid‐treated SY5Y cells (2001) (127)
Consensus Paper of the WFSBP Task Force on Biological Markers of Dementia: The role of CSF and blood analysis in the early and differential diagnosis of dementia (2005) (125)
The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease (2003) (123)
EVIDENCE THAT ALZHEIMER NEUROFIBRILLARY TANGLES ORIGINATE FROM NEUROTUBULES (1979) (122)
Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies. (2008) (121)
Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. (2006) (121)
Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis (2007) (120)
Ultrastructure of Paired Helical Filaments of Alzheimer's Neurofibrillary Tangle (1984) (120)
Down‐regulation of cAMP‐dependent protein kinase by over‐activated calpain in Alzheimer disease brain (2007) (117)
Protein changes in senile dementia. (1974) (115)
PKA modulates GSK‐3β‐ and cdk5‐catalyzed phosphorylation of tau in site‐ and kinase‐specific manners (2006) (113)
Anesthesia induces phosphorylation of tau. (2009) (112)
Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients (2002) (107)
Involvement of in the abnormal hyperphosphorylation of tau and its reversal by Memantine (2006) (107)
Dynamic Regulation of Expression and Phosphorylation of Tau by Fibroblast Growth Factor-2 In Neural Progenitor Cells from Adult Rat Hippocampus (1999) (105)
Tau passive immunization inhibits not only tau but also Aβ pathology (2017) (104)
ALUMINIUM AND ALZHEIMER'S DISEASE (1977) (101)
Discoveries of tau, abnormally hyperphosphorylated tau and others of neurofibrillary degeneration: a personal historical perspective. (2006) (101)
Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2 PP2A/SET (2011) (100)
Metabolic/signal transduction hypothesis of Alzheimer’s disease and other tauopathies (2005) (99)
Alzheimer disease therapeutics: focus on the disease and not just plaques and tangles. (2014) (97)
Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5 (2002) (97)
Role of tau phosphorylation by glycogen synthase kinase-3β in the regulation of organelle transport (2004) (96)
Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice (2014) (95)
Alzheimer's disease : advances in etiology, pathogenesis, and therapeutics (2001) (93)
Purification and characterization of two forms of Ca2+-activated neutral protease from calf brain. (1983) (93)
Alzheimer paired helical filaments: Bulk isolation, solubility, and protein composition (2004) (93)
Brain ubiquitin is markedly elevated in Alzheimer disease (1991) (91)
Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation (2015) (91)
Activation of Asparaginyl Endopeptidase Leads to Tau Hyperphosphorylation in Alzheimer Disease* (2013) (91)
Hyperphosphorylation determines both the spread and the morphology of tau pathology (2016) (88)
τ and ubiquitin in the human hypothalamus in aging and Alzheimer's disease (1992) (88)
Multifactorial Hypothesis and Multi-Targets for Alzheimer's Disease. (2018) (87)
Differential Effects of an O-GlcNAcase Inhibitor on Tau Phosphorylation (2012) (87)
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A (2011) (86)
Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice (2010) (85)
Targeting Tau Protein in Alzheimer’s Disease (2010) (84)
Defective brain microtubule assembly in Alzheimer??s disease (1987) (81)
Hyperphosphorylation-Induced Tau Oligomers (2013) (81)
Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) Modulates Serine/Arginine-rich Protein 55 (SRp55)-promoted Tau Exon 10 Inclusion* (2012) (81)
Inactivation of glycogen synthase kinase‐3 by protein kinase C δ: implications for regulation of τ phosphorylation (2000) (81)
Isolation of neurons and glial cells from normal and pathological human brains. (1972) (80)
Tau pathology involves protein phosphatase 2A in Parkinsonism-dementia of Guam (2014) (80)
Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain (2000) (80)
Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals (1994) (79)
Inhibitors of protein phosphatase‐2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau (2005) (78)
Developmental Regulation of Protein O-GlcNAcylation, O-GlcNAc Transferase, and O-GlcNAcase in Mammalian Brain (2011) (78)
Cytosolic abnormally hyperphosphorylated tau but not paired helical filaments sequester normal MAPs and inhibit microtubule assembly. (2008) (77)
Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice (2014) (77)
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques (2004) (77)
Regulation between O‐GlcNAcylation and phosphorylation of neurofilament‐M and their dysregulation in Alzheimer disease (2008) (76)
Chronic cerebral hypoperfusion causes decrease of O-GlcNAcylation, hyperphosphorylation of tau and behavioral deficits in mice (2014) (76)
Dephosphorylation of microtubule‐associated protein tau by protein phosphatase 5 (2003) (75)
Alzheimer disease: correlation of cerebro-spinal fluid and brain ubiquitin levels (1994) (75)
An experimental rat model of sporadic Alzheimer’s disease and rescue of cognitive impairment with a neurotrophic peptide (2011) (75)
Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease. (2011) (75)
The carboxy‐terminal fragment of inhibitor‐2 of protein phosphatase‐2A induces Alzheimer disease pathology and cognitive impairment (2010) (74)
Dysregulation of Protein Phosphorylation/Dephosphorylation in Alzheimer's Disease: A Therapeutic Target (2006) (74)
Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies (2015) (74)
Link Between DYRK1A Overexpression and Several-Fold Enhancement of Neurofibrillary Degeneration With 3-Repeat Tau Protein in Down Syndrome (2011) (73)
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine. (2006) (73)
Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease (2014) (71)
Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease (2015) (70)
Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease (2014) (70)
Regulation of phosphorylation of tau by cyclin‐dependent kinase 5 and glycogen synthase kinase‐3 at substrate level (2006) (70)
Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo (2019) (69)
I PP2A 1 Affects Tau Phosphorylation via Association with the Catalytic Subunit of Protein Phosphatase 2A* (2008) (69)
Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences (1987) (69)
Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease (1989) (69)
Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer’s disease (2016) (69)
Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer’s Disease (2018) (68)
Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices (2003) (68)
Juvenile Huntington chorea (1978) (67)
Ubiquitination and abnormal phosphorylation of paired helical filaments in Alzheimer's disease (2008) (67)
Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice (2018) (66)
O-GlcNAcylation: A regulator of tau pathology and neurodegeneration (2016) (65)
Enhancement of dentate gyrus neurogenesis, dendritic and synaptic plasticity and memory by a neurotrophic peptide (2011) (65)
Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach. (2000) (65)
Brain Gene Expression of a Sporadic (icv-STZ Mouse) and a Familial Mouse Model (3xTg-AD Mouse) of Alzheimer’s Disease (2012) (64)
Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer’s Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade (2017) (64)
Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage. (2009) (63)
From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. (2006) (62)
Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial. (2010) (61)
Immunoreactivity of neuronal lipofuscin with monoclonal antibodies to the amyloid β-protein (1989) (61)
Neurogenic and Neurotrophic Effects of BDNF Peptides in Mouse Hippocampal Primary Neuronal Cell Cultures (2013) (60)
Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain (2004) (60)
The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer. (1991) (60)
Subcellular distribution of protein phosphatases and abnormally phosphorylated τ in the temporal cortex from Alzheimer's disease and control brains (1998) (60)
Microtubule associated protein tau binds to double-stranded but not single-stranded DNA (2003) (58)
Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration (2002) (57)
Cytoplasmic Retention of Protein Phosphatase 2A Inhibitor 2 (I2PP2A) Induces Alzheimer-like Abnormal Hyperphosphorylation of Tau* (2014) (57)
Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation (2015) (57)
Assessments of the accumulation severities of amyloid β-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains (2006) (56)
Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice (2017) (55)
Abnormally phosphorylated tau in SY5Y human neuroblastoma cells (1995) (55)
A silver impregnation method for labeling both Alzheimer paired helical filaments and their polypeptides separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (1991) (55)
Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease (2014) (54)
Silver Labeling of Alzheimer Neurofibrillary Changes and Brain β-Amyloid (1993) (54)
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer’s disease (2013) (53)
Chemical pathology of neurofibrils. Neurofibrillary tangles of Alzheimer's presenile-senile dementia. (1975) (53)
Post-translational modifications of tau protein. (2006) (53)
Cyclic AMP-dependent Protein Kinase Regulates the Alternative Splicing of Tau Exon 10 (2011) (53)
Significance and mechanism of alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion (2002) (52)
Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A (2012) (52)
TAU AND UBIQUITIN IMMUNOREACTIVITY AT DIFFERENT STAGES OF FORMATION OF ALZHEIMER NEUROFIBRILLARY TANGLES (1989) (50)
Inhibition of Protein Synthesis Alters Protein Degradation through Activation of Protein Kinase B (AKT)* (2013) (49)
Intranasal Insulin Prevents Anesthesia-Induced Spatial Learning and Memory Deficit in Mice (2016) (49)
Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies (2017) (49)
Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated τ by neuroleptics (1996) (49)
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice (2015) (48)
OLIGODENDROGLIA FROM HUMAN AUTOPSIED BRAIN: BULK ISOLATION AND SOME CHEMICAL PROPERTIES 1 (1977) (47)
Neurofibrillary and Synaptic Pathology in the Aged Brain (1981) (46)
ALZHEIMER'S DISEASE AND RELATED CONDITIONS (1987) (46)
Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I (2015) (46)
Alzheimer paired helical filaments: Immunochemical identification of polypeptides (2004) (45)
Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease. (2009) (45)
Chemical relationship of the paired helical filaments of Alzheimer's dementia to normal human neurofilaments and neurotubules (1978) (45)
Opportunities and challenges in developing Alzheimer disease therapeutics (2011) (45)
Folding of Alzheimer's core PHF subunit revealed by monoclonal antibody 423 (2004) (45)
Bilateral injection of isoproterenol into hippocampus induces Alzheimer‐like hyperphosphorylation of tau and spatial memory deficit in rat (2005) (44)
Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice (2014) (44)
Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound (2014) (43)
Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice (2010) (43)
Corrigendum: Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation (2016) (43)
Ageing of the brain and dementia (1980) (42)
Neurofibrillary pathology leads to synaptic loss and not the other way around in Alzheimer disease. (2002) (42)
TDP-43 suppresses tau expression via promoting its mRNA instability (2016) (41)
Alzheimer's disease and related disorders. Etiology, pathogenesis and therapeutics (1999) (41)
Phosphothreonine-212 of Alzheimer Abnormally Hyperphosphorylated Tau is a Preferred Substrate of Protein Phosphatase-1 (2005) (40)
The loss of neuron-specific proteins during the course of Wallerian degeneration of optic and sciatic nerve (1981) (40)
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. (2008) (40)
Beneficial effect of a CNTF tetrapeptide on adult hippocampal neurogenesis, neuronal plasticity, and spatial memory in mice. (2010) (39)
Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain. (2001) (39)
Mechanism of neurofibrillary degeneration in Alzheimer's disease (1994) (39)
Alzheimer neurofibrillary tangles: Monoclonal antibodies to inherent antigen(s) (2004) (38)
Developing pharmacological therapies for Alzheimer disease (2007) (38)
Paired helical filaments associated with Alzheimer disease are readily soluble structures (1986) (38)
Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease. (2011) (37)
PP2B isolated from human brain preferentially dephosphorylates Ser-262 and Ser-396 of the Alzheimer disease abnormally hyperphosphorylated tau (2006) (37)
Calcium activated proteolysis of fibrous proteins in central nervous system. (1981) (37)
Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation. (2000) (37)
Comparison of the phosphorylation of microtubule-associated protein tau by non-proline dependent protein kinases (1994) (37)
Expression of Tau Pathology-Related Proteins in Different Brain Regions: A Molecular Basis of Tau Pathogenesis (2017) (36)
Regulation of Phosphorylation of tau by Protein Kinases in Rat Brain (2000) (36)
Regulation of expression, phosphorylation and biological activity of tau during differentiation in SY5Y cells (1999) (36)
Diverse regulation of AKT and GSK‐3β by O‐GlcNAcylation in various types of cells (2012) (36)
Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity: A biomarker of blood–cerebrospinal fluid barrier permeability (2010) (36)
Inhibition of neurofibrillary degeneration: a promising approach to Alzheimer's disease and other tauopathies. (2004) (36)
ON NEUROFILAMENT and NEUROTUBULE PROTEINS FROM HUMAN AUTOPSY TISSUE (1977) (35)
Ultracytochemical distribution of myelin basic protein after injection into the cerebrospinal fluid Evidence for transport through the blood-brain barrier and binding to the luminal surface of cerebral veins (1984) (35)
Alzheimer neurofibrillary tangles contain 2.1 nm filaments structurally identical to the microtubule-associated protein τ: a high-resolution transmission electron microscope study of tangles and senile plaque core amyloid (1992) (35)
Tau and ubiquitin in the human hypothalamus in aging and Alzheimer's disease. (1992) (35)
Non-proline-dependent protein kinases phosphorylate several sites found in tau from Alzheimer disease brain (1996) (35)
Molecular Mechanism of Alzheimer's Neurofibrillary Degeneration and Therapeutic Intervention a (1996) (34)
Elevated Levels of τ and Ubiquitin in Brain and Cerebrospinal Fluid in Alzheimer's Disease (1997) (34)
Pharmacological approaches of neurofibrillary degeneration. (2005) (33)
The organization of the microtubule associated protein tau in Alzheimer paired helical filaments (1993) (33)
Neurofibrillary Pathology: An Update (1977) (32)
Differential phosphorylation of human tau isoforms containing three repeats by several protein kinases. (1996) (32)
Truncation of Tau selectively facilitates its pathological activities (2020) (32)
Recent developments with tau-based drug discovery (2018) (31)
Hyperphosphorylation-induced self assembly of murine tau: a comparison with human tau (2005) (31)
Alzheimer abnormally phosphorylated tau is more hyperphosphorylated than the fetal tau and causes the disruption of microtubules (1995) (30)
Mechanism of Tau Hyperphosphorylation Involving Lysosomal Enzyme Asparagine Endopeptidase in a Mouse Model of Brain Ischemia. (2018) (30)
Rescue of Synaptic Failure and Alleviation of Learning and Memory Impairments in a Trisomic Mouse Model of Down Syndrome (2011) (29)
No evidence for aluminum in etiology and pathogenesis of alzheimer's disease (1986) (29)
Effect of Melatonin and Melatonylvalpromide on β-amyloid and Neurofilaments in N2a Cells (2008) (28)
A Novel Therapeutic Approach to Treat Alzheimer’s Disease by Neurotrophic Support During the Period of Synaptic Compensation (2018) (27)
O-GlcNAc cycling modulates neurodegeneration (2012) (27)
PAIRED HELICAL FILAMENT ANTIGEN IN CSF (1985) (27)
Alzheimer neurofibrillary degeneration (2007) (26)
Guanosine Triphosphate Binding to β‐Subunit of Tubulin in Alzheimer's Disease Brain: Role of Microtubule‐Associated Protein τ (1995) (26)
Protein abnormalities in Huntington's chorea. (1974) (26)
Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection (2014) (26)
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) enhances tau expression. (2013) (26)
A pool of β‐tubulin is hyperphosphorylated at serine residues in Alzheimer disease brain (2001) (25)
Novel therapeutic strategies for neurodegenerative disease (2009) (25)
Are Alzheimer neurofibrillary tangles insoluble polymers? (1986) (25)
Pathological Alterations of Tau in Alzheimer’s Disease and 3xTg-AD Mouse Brains (2019) (25)
Enhancement of neurogenesis and memory by a neurotrophic peptide in mild to moderate traumatic brain injury. (2015) (25)
O-GlcNAcylation Reduces Ischemia-Reperfusion–Induced Brain Injury (2017) (24)
NF-κB precursor, p105, and NF-κB inhibitor, IκBγ, are both elevated in Alzheimer disease brain (2005) (24)
Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: Negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation (2005) (24)
Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats. (2015) (24)
Intranasal Insulin Prevents Anesthesia-Induced Cognitive Impairment and Chronic Neurobehavioral Changes (2017) (24)
Encephalitogenic properties of purified preparations of bovine oligodendrocytes tested in guinea pigs (1978) (23)
Relapsing experimental allergic encephalomyelitis induced with isolated myelin and with myelin basic protein plus myelin lipids (1981) (23)
X‐ray structure of the PHF core C‐terminus: Insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease (2007) (23)
Synaptic Compensation as a Probable Cause of Prolonged Mild Cognitive Impairment in Alzheimer's Disease: Implications from a Transgenic Mouse Model of the Disease. (2017) (23)
Clinical symptoms and symptom signatures of Alzheimer's disease subgroups. (2013) (22)
GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner. (2015) (22)
Sera from Children with Autism Induce Autistic Features Which Can Be Rescued with a CNTF Small Peptide Mimetic in Rats (2015) (22)
Alzheimer's disease and related disorders : research advances (2003) (22)
Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer’s-like memory deficits in the Ts65Dn mouse model of Down syndrome (2017) (22)
Molecular pathology of Alzheimer neurofibrillary degeneration. (1993) (21)
Mechanism of Alzheimer neurofibrillary degeneration and the formation of tangles (1997) (21)
Alzheimer’s disease brain contains tau fractions with differential prion-like activities (2021) (21)
What is aging? What is its role in Alzheimer's disease? What can we do about it? (2005) (21)
Alzheimer's disease: paired helical filament immunoreactivity in cerebrospinal fluid (2004) (21)
Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound (2017) (20)
Inhibitors of protein phosphatase-2A: topography and subcellular localization. (2004) (20)
Alzheimer disease is multifactorial and heterogeneous (2000) (20)
Splicing factor SC35 promotes tau expression through stabilization of its mRNA (2011) (19)
Alzheimer paired helical filaments, untreated and pronase digested, studied by vertical platinum-carbon replication and high resolution transmission electron microscopy (1995) (19)
Studies on the encephalitogenic effects of purified preparations of human and bovine oligodendrocytes (1977) (19)
Up-regulation of casein kinase 1ε is involved in tau pathogenesis in Alzheimer’s disease (2017) (19)
Protein kinase C and calcium/calmodulin-dependent protein kinase II phosphorylate three-repeat and four-repeat tau isoforms at different rates (1997) (19)
Animal models of the sporadic form of Alzheimer's disease: focus on the disease and not just the lesions. (2013) (19)
Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain. (2018) (18)
Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice. (2011) (18)
Intranasal Administration of Insulin Reduces Chronic Behavioral Abnormality and Neuronal Apoptosis Induced by General Anesthesia in Neonatal Mice (2019) (18)
Memantine Attenuates Alzheimer’s Disease-Like Pathology and Cognitive Impairment (2015) (18)
RELATIONSHIPS AMONG THE CEREBRAL AMYLOID PEPTIDES AND THEIR PRECURSORS (1989) (18)
Hyperphosphorylated tau in SY5Y cells: similarities and dissimilarities to abnormally hyperphosphorylated tau from Alzheimer disease brain (1999) (17)
Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration. (2002) (17)
CSF phospho-tau correlates with behavioural decline and brain insoluble phospho-tau levels in a rat model of tauopathy (2010) (16)
Role of ciliary neurotrophic factor in the proliferation and differentiation of neural stem cells. (2013) (16)
Alzheimer paired helical filaments: Identification of polypeptides with monoclonal antibodies (2004) (16)
Shifting balance from neurodegeneration to regeneration of the brain: a novel therapeutic approach to Alzheimer's disease and related neurodegenerative conditions (2014) (16)
Cyclic AMP‐dependent protein kinase regulates 9G8‐mediated alternative splicing of tau exon 10 (2012) (16)
ALZHEIMER'S DISEASE, MICROTUBULE AND NEUROFILAMENT PROTEINS, AND AXOPLASMIC FLOW (1987) (16)
Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury (2018) (16)
Tau pathology generated by overexpression of tau. (1999) (16)
Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice (2020) (16)
From tangles to tau protein. (2006) (15)
Prevention of Amyloid-β and Tau Pathologies, Associated Neurodegeneration, and Cognitive Deficit by Early Treatment with a Neurotrophic Compound. (2017) (15)
Cytoskeletal protein pathology and the formation of beta-amyloid fibers in Alzheimer's disease (1989) (15)
NF-kappaB precursor, p105, and NF-kappaB inhibitor, IkappaBgamma, are both elevated in Alzheimer disease brain. (2005) (15)
Tau in cerebrospinal fluid: A sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification (2007) (15)
Bovine and human tau, highly homologous but less crossreactive: implications for Alzheimer disease. (1995) (15)
THE ENCEPHALITOGENIC ACTIVITY AND MYELIN BASIC PROTEIN CONTENT OF ISOLATED OLIGODENDROGLIA (1977) (14)
Biological markers in Alzheimer's disease. (2006) (14)
Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Nonbinding Phosphatase Activities (2001) (14)
MICROTUBULE ASSOCIATED PROTEIN, TAU IS A MAJOR CONSTITUENT OF ALZHEIMER PAIRED HELICAL FILAMENTS (1986) (14)
Neuronal O-GlcNAc transferase regulates appetite, body weight, and peripheral insulin resistance (2018) (14)
Elevated protein levels of protein phosphatases PP-2A and PP-2B in astrocytes of Alzheimer's disease temporal cortex (2005) (13)
IMMUNOREACTIVITY OF NEURONAL LIPOFUSCIN WITH MONOCLONAL ANTIBODIES TO THE AMYLOID BETA PROTEIN (1988) (13)
Elevated Tau Level in Aged Rat Cerebrospinal Fluid Reduced by Treatment with a Neurotrophic Compound. (2015) (13)
40 ISOLATION AND PROPERTIES OF ALZHEIMER NEUROFIBRILLARY TANGLES (1981) (13)
Protein Phosphatase 1 dephosphorylates TDP‐43 and suppresses its function in tau exon 10 inclusion (2018) (13)
Microanalysis of Alzheimer disease NFT and plaques (1990) (12)
Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice (2020) (12)
A novel monoclonal antibody DC63 reveals that inhibitor 1 of protein phosphatase 2A is preferentially nuclearly localised in human brain (2007) (12)
In vitro analysis of tau phosphorylation sites and its biological activity. (2002) (11)
Immune electron microscopic characterization of monoclonal antibodies to Alzheimer neurofibrillary tangles. (1992) (11)
Cyclic AMP-Dependent Protein Kinase Enhances SC35-Promoted Tau Exon 10 Inclusion (2014) (11)
Elevation of casein kinase 1ε associated with TDP‐43 and tau pathologies in Alzheimer's disease (2020) (11)
Alzheimer Neurofibrillary tangle: morphology and biochemistry. (1982) (10)
Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer’s Disease (2022) (10)
Multiple Forms of Phosphatase from Human Brain: Isolation and Partial Characterization of Affi-Gel Blue Binding Phosphatases (2004) (10)
I 1 PP 2 A Affects Tau Phosphorylation via Association with the Catalytic Subunit of Protein Phosphatase 2 A * (2008) (10)
Guanosine triphosphate binding to beta-subunit of tubulin in Alzheimer's disease brain: role of microtubule-associated protein tau. (1995) (10)
Alzheimer paired helical filaments: Cross-reacting polypeptide/s normally present in brain (2004) (10)
Regulation of microtubule-associated proteins, protein kinases and protein phosphatases during differentiation of SY5Y cells. (2004) (10)
In vitro assembly and isolation of neurofilaments and microtubules from mammalian CNS. (1987) (10)
Neuronal cytoskeleton in aging and dementia. (1986) (9)
Aluminum and the central nervous system. (1985) (9)
C‐terminal truncation of GSK‐3β enhances its dephosphorylation by PP2A (2017) (9)
Anesthesia with sevoflurane or isoflurane induces severe hypoglycemia in neonatal mice (2020) (9)
Tau phosphatase activity as a therapeutic target for AD. (1998) (9)
A SILVER IMPREGNATION METHOD SPECIFIC FOR ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) STAINS MICROTUBULE ASSOCIATED PROTEIN TAU.: 4 (1987) (8)
HYPERPHOSPHORYLATION DETERMINES BOTH THE SPREAD AND THE MORPHOLOGY OF TAU PATHOLOGY (2016) (8)
Alterations of the Neuronal Cytoskeleton in Alzheimer’s Disease and Related Conditions (1987) (8)
Intranasal Insulin Increases Synaptic Protein Expression and Prevents Anesthesia-Induced Cognitive Deficits Through mTOR-eEF2 Pathway. (2019) (8)
49 STUDIES ON MAMMALIAN NEUROFILAMENTS ISOLATED BY IN VITRO ASSEMBLY-DISASSEMBLY (1981) (8)
Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice (2019) (8)
CENTRAL CHOLINERGIC ACTIVITY IN ALZHEIMER DEMENTIA (1980) (7)
Alzheimer paired helical filaments (PHFs) studied by high‐resolution TEM: What can vertical Pt‐C replication tell us about the organization of the pronase‐digested PHF core? (2005) (7)
Laboratory diagnostic tests for Alzheimer's disease. (1989) (7)
Stratification of patients is the way to go to develop neuroprotective/disease-modifying drugs for Alzheimer's disease. (2008) (7)
Inhibition of AMD-Like Pathology With a Neurotrophic Compound in Aged Rats and 3xTg-AD Mice (2019) (7)
Reduction of neuronal specific protein and some neurotransmitters in the infantile neuroaxonal dystrophy (INAD). (1982) (7)
P.4.018 Memantine restores okadaic acid-induced changes in the activities of protein phosphatase-2A, CaMKII and hyperphosphorylation of tau in rat hippocampal slices in culture (2003) (6)
Alzheimer's disease research in Ibero America (2016) (6)
COEXISTENCE OF TWO TYPES OF PAIRED HELICAL FILAMENTS IN ALZHEIMERʼS DISEASED BRAINS (1986) (6)
Paired helical filaments associated with Alzheimer??s disease are readily soluble structures (1987) (6)
Brain glutamate decarboxylase and cholinergic enzyme activities in scrapie (1985) (6)
Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin (2019) (6)
Immunocytochemical studies on neurofibrillary changes. (1982) (6)
Paired Helical Filaments (PHF): Update 1988 (1988) (5)
Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer's disease (2011) (5)
Alzheimer Neurofibrillary Degeneration: A Feasible and Key Target for Therapeutics (1997) (5)
Huntington disease (1978) (5)
IMMUNE ELECTRON MICROSCOPY OF PAIRED HELICAL FILAMENTS (PHF) WITH TAU ANTIBODIES: 132 (1987) (5)
Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice (2020) (5)
Morphological and chemical characterization of a starch granule-like polyglucosan deposit isolated from human brain (2004) (4)
P3-329 I1 PP2A and I2 PP2A affect tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A (2006) (4)
MICROTUBLE ASSOCIATED PROTEIN, TAU IS ABNORMALLY PHOSPHORYLATED IN ALZHEIMER BRAIN (1986) (4)
Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction (2021) (4)
79 STUDIES ON ALZHEIMER NEUROFIBRILLARY TANGLE CROSS-REACTING ANTIGEN/S (1980) (4)
The solubility controversy of paired helical filaments: A commentary (2004) (4)
Alzheimer's disease: Scientific progress for future trends (1993) (4)
Cerebrospinal Fluid Secretory Ca 2 -Dependent Phospholipase A 2 Activity Is Increased in (2009) (4)
CHARACTERIZATION OF THE CEREBRAL AMYLOID PEPTIDES AND THEIR PRECURSORS: 18 (1990) (3)
MICROTUBULE ASSOCIATED PROTEIN TAU IN ALZHEIMER PAIRED HELICAL FILAMENTS (PHF): HOW MUCH? (1987) (3)
Glycosylation of tau protein occurs earlier than its hyperphosphorylation in Alzheimer's disease (2000) (3)
159 IDENTIFICATION OF ALZHEIMER PAIRED HELICAL FILAMENT POLYPEPTIDES WITH MONOCLONAL ANTIBODIES (1984) (3)
Tau-induced neurodegeneration: a clue to its mechanism. (2005) (3)
IMMUNE ELECTRON MICROSCOPY OF ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) (1986) (3)
AD/SDAT, plaques, tangles and BBB changes (1986) (3)
Histopathological classification of dementias by multivariate data analysis. (1989) (3)
The peptidergic antidementia drug cerebrolysin increases neurogenesis in the adult rat dentate gyrus and improves spatial learning and memory (2000) (3)
Cytoskeletal alterations in the hypothalamus during aging and in Alzheimer's disease are not necessarily a marker for impending cell death (1991) (3)
108 SEARCH FOR SECONDARY ANTIGENS IN THE PATHOGENESIS OF RELAPSING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (1980) (3)
Ubiquitin in cerebrospinal fluid: a rapid competitive enzyme‐linked immunoflow assay (1994) (3)
Second international conference on Alzheimer's disease and related disorders, Toronto 1990: Review of current research (1991) (2)
168 Differential phosphorylation of three-repeat human tau isoforms by several protein kinases (1996) (2)
Bulk isolation of neurofibrillary tangles and discoveries of tau and its abnormal hyperphosphorylation (2006) (2)
Expression of Microtubule Associated Protein Tau in Mouse Pancreatic Islets Is Restricted to Autonomic Nerve Fibers. (2020) (2)
Sevoflurane-induced neuronal apoptosis in neonatal mice is prevented with intranasal administration of insulin. (2020) (2)
ARE NEUROTUBULE PROTEINS INVOLVED IN THE FORMATION OF ALZHEIMER NEUROFIBRILLARY TANGLES?: 65 (1979) (2)
P-044 Accurate and early detection of Alzheimer’s disease using a gene expression signature in blood (2007) (2)
S5-02-05 Involvement of aberrant regulation of PI3K and MAPK cascades in AD TAU phosphorylation (2004) (2)
Intranasal insulin prevents anesthesia-induced spatial memory deficit in mice (2015) (2)
A molecular mechanism by which acidosis of the brain can lead to Alzheimer's disease (2013) (2)
Rbfox3/NeuN Regulates Alternative Splicing of Tau Exon 10. (2018) (2)
534 Tau-pathology in brain of rats after chronic treatment with okadaic acid (1996) (2)
Transgenic mice harbouring glycogen synthase kinase-3beta transgenes as a route for manipulating tau phosphorylation in vivo. (1995) (2)
Pivotal Role of Neurofibrillary Degeneration in Alzheimer Disease and Therapeutic Targets (2004) (2)
Neurogenesis: A Promising Therapeutic Target for Alzheimer Disease and Related Disorders (2004) (2)
Seeding-Competent Tau in Gray Matter Versus White Matter of Alzheimer's Disease Brain. (2021) (2)
Regional distribution of choline acetyltransferase and acetylcholinesterase in rabbit brain (1980) (2)
Biology of Alzheimer's disease through biochemistry of tangles and plaques (1986) (2)
Thiamme2-G, A Novel O-GlcNAcase Inhibitor, Reduces Tau Hyperphosphorylation and Rescues Cognitive Impairment in Mice. (2021) (2)
Regulation of tau phosphorylation in normal and diseased cells. (1999) (1)
CREB regulates the expression of neuronal glucose transporter 3: A mechanism leading to impaired brain glucose uptake in Alzheimer's disease (2012) (1)
ABNORMALLY PHOSPHORYLATED TAU IN ALZHEIMER DISEASE BRAIN: ROLE OF PHOSPHOPROTEIN PHOSPHATASES (1993) (1)
TRACE METAL ANALYSIS OF PLAQUES AND TANGLES IN ALZHEIMER'S DISEASE (1988) (1)
Proteolytic activity in brains of rabbits treated with aluminum (1985) (1)
P4-425 High throughput screen assays of inhibition of PP-2A catalyzed dephosphorylation of abnormally hyperphosphorylated tau by I1PP2A and I2PP2A (2004) (1)
C-TERMINAL TRUNCATION OF GSK-3β ENHANCES ITS DEPHOSPHORYLATION BY PP2A (2017) (1)
PATHOLOGICAL TAU FROM ALZHEIMER'S BRAIN INDUCES SITE-SPECIFIC HYPERPHOSPHORYLATION AND SDS- AND REDUCING AGENT-RESISTANT HIGH MOLECULAR WEIGHT AGGREGATION OF TAU IN VIVO (2019) (1)
A novel etiopathogenic mechanism and a disease-relevant non-transgenic rat model of Alzheimer's disease (2010) (1)
163 Enhancement of Adult Hippocampal Neurogenesis by a Neurotrophic Peptide in Traumatic Brain Injury (2013) (1)
O2-01-02 Treat abnormal hyperphosphorylation and not aggregation of tau (2006) (1)
TAU- PATHOLOGY IN HIPPOCAMP AL FORMATION OF AGED DOGS AND RATS CHRONICALLY TREATED WITH OKADAIC ACID (1997) (1)
Tau Pathology as a Target in Alzheimer's Therapeutics (2007) (1)
Abnormal hyperphosphorylation of non-tau proteins in Alzheimer's disease brain (2000) (1)
IN VITRO ASSEMBLY OF MICROTUBULES AND NEUROFILAMENTS FROM ALZHEIMER BRAIN: 71 (1982) (1)
Seizure susceptibility and hippocampal network hypersynchrony at a young age in a triple transgenic mouse model of Alzheimer’s disease (2015) (1)
Alzheimer??s disease, microtubule and neurofilament proteins, and axoplasmic flow (1987) (1)
Overexpression of inhibitor-1 or -2 of protein phosphatase-2A causes abnormal hyperphosphorylation of tau and cognitive impairment in the rat (2009) (1)
PAIRED HELICAL FILAMENT (PHF) IMMUNOREACTIVITY IN CSF (1988) (1)
Chronic treatment with a CNTF peptide enhances neuronal plasticity and alleviates cognitive impairment in 3xTgAD mice (2010) (1)
Preclinical basis for the efficacy of memantine in Alzheimer’s disease (2005) (1)
MICROTUBULE ASSOCIATED PROTEIN TAU: IDENTIFICATION AND LOCALIZATION OF A NOVEL PEPTIDE TO ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) (1989) (1)
Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase 2A and 2B J.Z. Wang, C.-X. Gong, I. Grundke-Iqbal and K. Iqbal. NYS Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314 USA (1994) (1)
A NOVEL PHARMACOLOGIC THERAPEUTIC APPROACH TO ALZHEIMER DISEASE AND COGNITIVE AGING (2014) (1)
P3-063: CSF phospholipase A2 activity is a biomarker of blood brain barrier permeability but not Alzheimer's disease (2008) (1)
Tau seeding activity in various regions of down syndrome brain assessed by two novel assays (2022) (1)
Chapter 13:A Non-transgenic Rat Model of Sporadic Alzheimer's Disease (2011) (1)
109 RELATIONSHIP OF ALZHEIMER PAIRED HELICAL FILAMENTS WITH MICROTUBULES AND NEUROFILAMENTS (1983) (1)
Neural Regeneration as a Disease-Modifying Therapeutic Strategy for Alzheimer’s Disease (2017) (1)
INTRANASAL ADMINISTRATION OF INSULIN PREVENTS ANESTHESIA-INDUCED COGNITIVE IMPAIRMENT AND CHRONIC NEUROBEHAVIORAL CHANGES (2017) (1)
Subgroups of Alzheimer disease based on levels of CSF tau, ubiquitin and Aβ1−42 (2000) (1)
P2-128 Regulation of microtubule-associated proteins, protein kinases, and protein phosphatases during differentiation of SY5Y cells (2004) (1)
P3-251 Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain (2004) (1)
P2-445: Enhancement of dentate gyrus neurogenesis and associated memory by a neurotrophic peptide (2008) (0)
Reversal Of Cognitive Impairment By Pharmacologic Neuroregeneration: A Novel Therapeutic Approach (2010) (0)
O2-05-08: Protein O-Glcnacylation: A novel mechanism involved in Alzheimer's disease (2008) (0)
P2-155: Phosphorylation of SC35 by Dyrk1A inhibits its promotion of tau exon 10 inclusion (2008) (0)
Overexpression of tau associates with differentiation of neuronal cells in culture (2000) (0)
110 SOLUBILITY AND PROTEIN COMPOSITION OF ALZHEIMER NEUROFIBRILLARY TANGLES (1983) (0)
Total-tau, Aβ1–42 and Ubiquitin in CSF in the diagnosis of Alzheimer disease (2002) (0)
P4-108 First indentified case of familial Alzheimer's disease in Europe associated with mutation (VAL717PHE) in the APP gene (2004) (0)
RESCUE OF NEUROTROPHIC DEFICIT DURING PRENATAL TO EARLY POSTNATAL DEVELOPMENT CAN PREVENT ALZHEIMER-LIKE COGNITIVE IMPAIRMENT LATER IN LIFE (2018) (0)
The Merits of Activation of Protein Phosphatase-2A as a Therapeutic Approach to Alzheimer Disease and Related Tauopathies (2014) (0)
Alzheimer Neurofibrillary Tangle and Its Relationship with Plaque Core Amyloid (1986) (0)
620 Interaction between Alzheimer disease abnormally phosphorylated Tau and microtubule associated proteins (1996) (0)
ISOLATION AND CHARACTERIZATION OF VESSELS AND AMYLOID STARS FROM CEREBRUM OF PATIENTS WITH SENILE DEMENTIA OF ALZHEIMER TYPE: 144 (1979) (0)
S2-04-02 Treatment of Alzheimer and other tauopathies by inhibition of neurofibrillary degeneration (2004) (0)
Rescue of cognitive impairment and neuronal plasticity with a neurotrophic peptide in a rat model of sporadic Alzheimer's disease (2012) (0)
7 Tau and Ubiquitin as diagnostic markers of Alzheimer disease (1996) (0)
Erratum: CSF biomarker variability in the Alzheimer's Association quality control program (Alzheimer's and Dementia (2013) 9 (251-261)) (2015) (0)
Neurogenic and neuroprotective effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures (2011) (0)
P3-240 I1 PP2A and I2 PP2A interact with the catalytic subunit of protein phosphatase 2A (2004) (0)
Histopathological criteria for progressive dementia disorders. Clinical to pathological correlation (1988) (0)
Development of neurotrophic peptides for enhancement of neurogenesis and associated behavioral improvement (2009) (0)
536 Tau in Alzheimer disease brain is phosphorylated to different degrees at different sites (1996) (0)
TEMPLATION AND PROPAGATION OF TAU PATHOLOGY BY ALZHEIMER TAU IN C57BL/6 MICE (2018) (0)
MOLECULAR MECHANISM OF TAU SPREAD AND TAU SITES TO TARGET FOR IMMUNOTHERAPY (2016) (0)
Subgroups of Alzheimer disease based on cerebrospinal fluid levels of molecular markers (2005) (0)
518 Secondary structure of Alzheimer disease abnormally hyperphosphorylated tau (AD P-Tau) before and after phosphate removal using hydroflouric acid: Correlation with high resolution TEM imaging (1996) (0)
O3-13-02 CHRONIC TREATMENT WITH A CNTF-DERIVED PEPTIDE REVERSES DENDRITIC AND SYNAPTIC PLASTICITY DEFICITS, COGNITIVE IMPAIRMENTAND TAU PATHOLOGY IN AN ALZHEIMER’S DISEASE MOUSE MODEL (2013) (0)
516 Expression of protein kinase GSK-3 and protein phosphatases PP-1, PP 2A, and PP-2B in the brain of patients with Alzheimer's disease (1996) (0)
[Association of microtubule promoting and binding activity of tau with its phosphorylation sites]. (2000) (0)
P1-358 Enhancement of neurogenesis by neurotrophic factors: a therapeutic approach to Alzheimer disease (2004) (0)
Truncation of GSK-3β by activated calpain I in Alzheimer brain enhances its biological activity (2010) (0)
Chronic treatment with an 11-mer CNTF peptide rescues synaptic deficit and cognitive impairment in a rat model of sporadic Alzheimer's disease (2011) (0)
MICROTUBULE ASSOCIATED PROTEIN TAU: IMMUNOCHEMICAL EVIDENCE FOR ITS PHOSPHORYLATION IN ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) (1989) (0)
Abnormal ) PP 2 A 2 Phosphatase 2 A Inhibitor 2 ( I Cytoplasmic Retention of Protein Neurobiology : (2014) (0)
Research Article Microtubule associated protein tau binds to double-stranded but not single-stranded DNA (2003) (0)
Chronic treatment with a CNTF-derived peptide reverses dendritic and synaptic plasticity deficits, cognitive impairment and tau pathology in an Alzheimer's disease mouse model (2013) (0)
TAU IMMUNOTHERAPY PREVENTS THE SPREAD AND PROMOTES THE CLEARANCE OF PATHOLOGY IN MICE (2017) (0)
Rescue of pathology and cognitive impairment by tau immunotherapy at a moderate to severe stage of the disease in 3xTg-alzheimer's disease mice (2015) (0)
P2-166: Atomic structure of the PHF core C-terminus (2008) (0)
Development of neuropeptides that promote neurogenesis in models of Alzheimer's and Parkinson's disease (2009) (0)
Molecular pathology of Alzheimer neurofibrillary (2009) (0)
IMMUNE ELECTRON MICROSCOPY OF MONOCLONAL ANTIBODIES TO ALZHEIMER NEUROFIBRILLARY TANGLES: 5 (1987) (0)
Dephosphorylation both diminishes and alters the spread of Alzheimer tau-induced pathology in mice (2015) (0)
P3-246 Association of P70 S6 kinase with neurofibrillary degeneration in Alzheimer's disease (2004) (0)
P4-339 Improvement of neurogenesis by cerebrolysin and its neurotrophic factors in adult rat hippocampal progenitors (2006) (0)
QUANTITATION OF MICROTOBULE ASSOCIATED PROTEIN TAU IN PAIRED HELICAL FILAMENTS BY IMMUNOASSAY (1988) (0)
AN ULTRASTRUCTURAL INVESTIGATION OF THE ROLE OF TAURINE IN VISUAL CORTEX ONTOGENY (1986) (0)
Fast Atom Bombardment, Tandem, and Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry in the Structure Determination of Amyloid Proteins Isolated from the Brain of Alzheimer's Disease Patients, (1992) (0)
1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France (2008) (0)
37 Promise and feasibility of inhibition of Tau's abnormal hyperphosphorylation (2012) (0)
Protein Kinase B (AKT) Protein Degradation through Activation of Inhibition of Protein Synthesis Alters (2014) (0)
515 Isolation of glycogen synthase kinase-3 (GSK-3) and cyclin-dependent kinase-S (cdk-S) from Alzheimer disease and control brains (1996) (0)
O4-05-04 Regeneration of the brain: a promising approach to neurodegeneration and disorders of learning and memory (2004) (0)
166 GUAM PARKINSONISM DEMENTIA: ACTIVITIES OF CHOLINERGIC AND GABAERGIC ENZYMES IN BRAIN (1984) (0)
Prevention of propagation of tau pathology with antibodies to its amino terminal domain (2016) (0)
Related articles (2014) (0)
621 The regulation of phosphorylation of Tau in SYSY neuroblastoma cells (1996) (0)
Upregulation of casein kinase 1 epsilon may be involved in tau pathology in Alzheimer's disease brain (2013) (0)
Overexpression of Dyrk1A dysregulates the alternative splicing of tau exon 10 (2010) (0)
182 INFANTILE NEUROAXONAL DYSTROPHY: MORPHOLOGICAL AND BIOCHEMICAL STUDIES (1980) (0)
Asparagine Endopeptidase (AEP) is activated in Alzheimer's disease brain and induces I2PP2A cleavage (2011) (0)
O-GLCNACYLATION AMELIORATES ISCHEMIA-INDUCED CEREBRAL INJURY (2016) (0)
Chapter 7:Alzheimer Neurofibrillary Degeneration: Pivotal Role and Therapeutic Targets (2010) (0)
Truncation and activation of Dyrk1A in Alzheimer's disease brain by activated calpain I (2009) (0)
P2-450: Cerebrolysin stimulates neurogenesis in the dentate gyrus: A basis for neuronal replacement therapy in Alzheimer's disease? (2008) (0)
O-GlcNAcylated tau: A link between impaired glucose metabolism and neurodegeneration in Alzheimer's disease (2012) (0)
TDP-43 REGULATES ALTERNATIVE SPLICING OF TAU EXON 10: IMPLICATION IN THE PATHOGENESIS OF TAUOPATHIES (2017) (0)
Kinase–Kinase and Site–Site Interactions in the Phosphorylation of Tau by GSK‐3 (2006) (0)
MICROTUBULE ASSOCIATED PROTEIN TAU: STRUCTURAL FEATURES AND ITS RELATIONSHIP TO ALZHEIMER'S NEUROFIBRILLARY TANGLES (1988) (0)
Truncation of GSK-3beta by calpain I contributes to the hyperphosphorylation of tau in the Alzheimer's brain (2012) (0)
DISSOCIATION OF GLOBULAR SUBUNITS FROM ISOLATED PAIRED HELICAL FILAMENTS (1986) (0)
Hyperphosphorylation and accumulation of neurofilament protein subunits in Alzheimer disease brain (2000) (0)
Rabbit IgG cross-reacts with Alzheimer neurofibrillary tangles (1994) (0)
β-N-Methylamino-L-alanine could be involved in Alzheimer's neurofibrillary pathology in amyotrophic lateral sclerosis–Parkinsonism dementia complex (2013) (0)
O2-01-06 Inhibition of more than one tau kinase might be required for prevention of Alzheimer disease (2007) (0)
P3-300 Increased tyrosine 307 phosphorylation of protein phosphatase-2A correlates with tau associated pathologies in Alzheimer’s disease (2006) (0)
P3-248 Activation of calpain I in Alzheimer disease brain negatively regulates CREB (2006) (0)
P3-264 A novel phosphoseryl/phosphothreonyl protein phosphatase activity that might be involved in the abnormal hyperphosphorylation of tau (2004) (0)
319 Alterations of presenilin I in fibroblasts from familial Alzheimer disease patients (1996) (0)
Excitotoxic damage deregulates tau phosphorylation: Implication to Alzheimer's disease (2009) (0)
572 Role of abnormal phosphorylation and glycosylation of tau in the formation of tangles and neurofibrillary degeneration (1996) (0)
MICROTUBULE ASSOCIATED PROTEIN TAU IN ALZHEIMER PAIRED HELICAL FILAMENTS (PHF): HOW MUCH? 134 (1987) (0)
IMMUNOTHERAPY-TARGETING TAU BLOCKS TAU PATHOLOGY INDUCED BY ALZHEIMER’S HYPERPHOSPHORYLATED TAU IN TRIPLE-TRANSGENIC AD MICE (2018) (0)
Cerebral ischemia-induced elevation of O-GlcNAcylation causes AKT inhibition and apoptosis (2012) (0)
Molecular basis of cognitive improvement of pioglitazone and rosiglitazone (2010) (0)
EVALUATION OF GTP BINDING SITE OF β‐SUBUNIT OF BRAIN TUBULIN IN ALZHEIMER DISEASE (1988) (0)
Exchangeable GTP binding site of the beta-subunit of brain tubulin in Alzheimer disease. (1989) (0)
P2-129 Tau and a cell culture model of microtubule stability (2004) (0)
Development of an ultrasensitive elisa-double enzyme amplification assay and quantitation of total and abnormally hyperphosphorylated taus in cerebrospinal fluid (2000) (0)
Role of protein kinases, protein phosphatases and extracellular signals in the abnormal hyperphosphorylation of tau (2000) (0)
Dyrk 1 A regulate the alternative splicing of tau exon 10 1 Dual-specificity tyrosine-phosphorylated and regulated kinase 1 A ( Dyrk 1 A ) modulates serine-arginine rich protein 55 ( SRp 55 )-promoted tau exon (2012) (0)
Chronic treatment with a CNTF peptide restores neurogenesis and alleviates memory deficit in Ts65Dn mice (2010) (0)
Alzheimer Neurofibrillary Tangles: Immunochemical Cross-Reactivity with Normal Brain Antigens (1985) (0)
Role of Abnormal Phosphorylation of Tau in Neurofibrillary Degeneration: Implications for Alzheimer Therapy (1994) (0)
P2-142: Decreased protein phosphatase 2A in Down syndrome brain: A cause of neurofibrillary degeneration (2008) (0)
Special Report from the Challenging Views of Alzheimer ’ s Disease What is aging ? What is its role in Alzheimer ’ s disease ? What can we do about it ? (2005) (0)
Tau immunotherapy rescues cognitive impairment by clearing extracellular tau (2020) (0)
532 Differentiation of SYSY cells: Effect on phosphorylation and biological activity of tau (1996) (0)
S4-01-01 Identification of subgroups of Alzheimer disease (2006) (0)
O2-05-06 Impaired glucose uptake/metabolism contributes to hyperphosphorylation of tau via reduction of O-GLCnacylation: a novel mechanism involved in Alzheimer disease (2004) (0)
First international conference on Alzheimer's disease and related disorders (1989) (0)
A protein phosphatase-2A-based etiopathogenic mechanism of Alzheimer's disease (2010) (0)
Technical Advance Levels of Nonphosphorylated and Phosphorylated Tau in Cerebrospinal Fluid of Alzheimer’s Disease Patients An Ultrasensitive Bienzyme-Substrate-Recycle Enzyme-Linked Immunosorbent Assay (2002) (0)
Regulation of Akt by O-GlcNAcylation in various cell types: implication in Alzheimer's Disease (2010) (0)
A NOVEL THERAPEUTIC APPROACH TO TREAT ALZHEIMER’S DISEASE DURING THE BRAIN’S SELF REPAIR ATTEMPT PERIOD (2017) (0)
Preventive effects of a neurotrophic compound on cognition and pathology in 3xTg-AD transgenic mouse model of Alzheimer’s disease (2015) (0)
Neurofibrillary degeneration: a promising target for the treatment of Alzheimer’s disease and other tauopathies (2005) (0)
Dendritic Alterations in a Tauopathy Rat Model of Alzheimer’s Disease Using PP2A Inhibition (2011) (0)
O4-04-08: Improvement of cognition with a neurogenic/neurotrophic peptide (2008) (0)
A 31 kilodalton beta-protein immunoreactive polypeptide in neuronal lipofuscin. (1989) (0)
P3-224 Inhibitors of protein phosphatase-2A colocalize with the abnormally hyperphosphorylated tau in Alzheimer disease (2004) (0)
P3-337 Enhancement of neurogenesis by peptides: A promising therapeutic approach (2006) (0)
P2-150 Detection of phosphorylated tau in cerebrospinal fluid of Alzheimer’s disease patients: An ultrasensitive bienzyme-substrate-recycle ELISA (2006) (0)
P1-267 Alterations of glycoproteins in Alzheimer disease brain (2004) (0)
Rats Display Sexual Dimorphism in Phosphorylation of Brain Tau with Age. (2021) (0)
In vitro self assembly of abnormally hyperphosphorylated tau into PHF-like structures (2000) (0)
P3-254 Hyperphosphorylation induced self-assembly of murine tau: a comparison with human tau (2004) (0)
Biochemical Markers for Alzheimer Disease as Reflection of the Neuropathology in Cerebrospinal Fluid: (2020) (0)
Metabolically active rat brain slices as a model for studying neurofibrillary degeneration of Alzheimer's disease (2000) (0)
Why delay in effective treatment for Alzheimer's disease and related conditions. (2019) (0)
Central Role of Tau Protein in Alzheimer»S Disease and Related Tauopathies (2009) (0)
533 Isolation of protein phosphatase 2B calcineurin from Alzheimer disease and control autopsied brains (1996) (0)
P3-222 Truncated tau is intimately involved in formation of PHF (2004) (0)
P2-148: Involvement of 9G8 in alternative splicing of tau exon 10 (2008) (0)
Chapter 15:Regeneration of Degenerated Brain: A Promising Therapeutic Target (2010) (0)
Gut Microbiota and Immunotherapy for Alzheimer’s Disease (2022) (0)
Improvement of cognition by enhancing neurogenesis and neuronal plasticity with a CNTF peptidergic compound (2011) (0)
P3-263 Phosphorylation of tau is regulated by O-Glcnacylation (2004) (0)
P2-145: Regulation of ASF-mediated alternative splicing of tau exon 10 by PKA (2008) (0)
Tau isoforms: Interaction with Alzheimer disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease like protein (2001) (0)
Effect of Peripheral Insulin Administration on Phosphorylation of Tau in the Brain. (2020) (0)
Alzheimer's disease and related disorders : proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988 (1989) (0)
531 Glycosylation of microtubule associated ρ: An abnormal posttranslational modification in Alzheimer disease (1996) (0)
Dysregulation of brain insulin signaling: A mechanistic link between diabetes and Alzheimer's disease (2010) (0)
The human hypothalamus and Alzheimer symptoms (1992) (0)
299 Abnormal hyperphosphorylation of tau: An early and most significant deleterious event in neurofibrillary degeneration (1996) (0)
O4-02-05: Molecular mechanism by which type 2 diabetes mellitus increases the risk for Alzheimer's disease (2008) (0)
S3-03-01 O-glycosylation regulates phosphorylation of tau:A novel mechanism leading to neurofibrillarydegeneration in Alzheimer disease (2006) (0)
SUBACUTE TO CHRONIC ALZHEIMER-LIKE ALTERATIONS AFTER CONTROLLED CORTICAL IMPACT IN TG/HTAU MICE (2019) (0)
Abnormal hyperphosphorylation of tau: Participation of β-amyloid/peptide out and proline-directed protein kinases (PDPKs) and non-PDPKs in (1995) (0)
INVOLVEMENT OF ACTIVATION OF ASPARAGINYL ENDOPEPTIDASE IN TAU HYPERPHOSPHORYLATION IN TRAUMATIC BRAIN INJURY (2018) (0)
163 ARE ALZHEIMER PAIRED HELICAL FILAMENT POLYPEPTIDES PRESENT NORMALLY IN BRAIN (1984) (0)
S1-04-04 Mutations in tau gene lead to neurodegeneration by making tau a more favorable substrate for abnormal hyperphosphorylation (2004) (0)
A FRAGMENT OF THE AMYLOID PRECURSOR PROTEIN IN NEURONAL LIPOFUSCIN?: 94 (1989) (0)
CLONING AND CHARACTERIZATION OF A cDNA ENCODING THE ALZHEIMER'S DISEASE AND DOWN'S SYNDROME AMYLOID PEPTIDE: 193 (1987) (0)
Quantitative neurofilament protein assay in Alzheimer disease cerebrospinal fluid (2000) (0)
Does proteopathic tau propagate trans-synaptically in the brain? (2022) (0)
Does proteopathic tau propagate trans-synaptically in the brain? (2022) (0)
P3-292 High throughput screen assay to develop drugs for inhibition of abnormal hyperphosphorylation of tau (2006) (0)
535 Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5 (1996) (0)
P2-147: Modulation of SRp55-regulated alternative splicing of tau exon 10 by Dyrk1A (2008) (0)
Role of Neurofibrillary Degeneration in Alzheimer’s Disease (1998) (0)
Alzheimer subgroups: towards effective drug development (2007) (0)
CYCLIC AMP-DEPENDENT PROTEIN KINASE PHOSPHORYLATES TDP-43 AND MODULATES ITS FUNCTION IN TAU MRNA PROCESSING (2019) (0)
ALZHEIMER’S DISEASE IN DOWN SYNDROME CAN BE PREVENTED BY PHARMACOLOGIC TREATMENT DURING PRENATAL TO EARLY POSTNATAL DEVELOPMENT (2017) (0)
P3-304 Mnb/Dyrk1A primes phosphorylation of tau at several phosphorylation sites by GSK-3β (2006) (0)
Alzheimer Neurofibrillary Tangles: Biochemical Properties (1985) (0)
ALUMINIUM AND ALZHEIMER'S DISEASE (1989) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Khalid Iqbal?

Khalid Iqbal is affiliated with the following schools:

Nantong University

Khalid Iqbal's Academic­Influence.com Rankings