Kim Barrett
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Research physiologist
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Biology
Kim Barrett's Degrees
- PhD Physiology University of California, San Francisco
- Doctorate Medicine University of California, San Francisco
Why Is Kim Barrett Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kim Elaine Barrett is a research physiologist, specialising in digestive disorders such as inflammatory bowel disease. She was Distinguished Professor of Medicine and Dean of the Graduate Division at University of California, San Diego before moving to her current position as Vice Dean for Research and Distinguished Professor of Physiology and Membrane Biology in the School of Medicine at University of California, Davis in 2021. She was the Editor-in-Chief of The Journal of Physiology from 2016–2022, and is a Past-President of the American Physiological Society.
Kim Barrett's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Ganong's Review of Medical Physiology (2010) (839)
- Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC) (2003) (622)
- Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects. (2000) (472)
- Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells (2003) (270)
- Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. (1997) (207)
- Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4 (1994) (191)
- Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion. (1998) (164)
- Carbachol-stimulated Transactivation of Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase in T84 Cells Is Mediated by Intracellular Ca2+, PYK-2, and p60 src * (2000) (161)
- Activation of mast cells by bile acids. (1991) (156)
- Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells. (2006) (148)
- Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides. (1986) (138)
- Positive and negative regulation of chloride secretion in T84 cells. (1993) (137)
- Inhibition of Ca2+-dependent Cl- secretion in T84 cells: membrane target(s) of inhibition is agonist specific. (1998) (133)
- Transactivation of the Epidermal Growth Factor Receptor in Colonic Epithelial Cells by Carbachol Requires Extracellular Release of Transforming Growth Factor-α* (2002) (132)
- Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells. (2005) (131)
- Leptin acts as a mitogenic and antiapoptotic factor for colonic cancer cells (2007) (125)
- Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice. (2005) (125)
- Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells. (1996) (118)
- Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2. (2002) (117)
- Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice. (2014) (115)
- Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells. (1998) (113)
- Phosphatidylinositol 3-Kinase Mediates the Inhibitory Effect of Epidermal Growth Factor on Calcium-dependent Chloride Secretion* (1996) (110)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2. (2009) (105)
- Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease. (2016) (99)
- A biologic function for an "orphan" messenger: D-myo-inositol 3,4,5,6-tetrakisphosphate selectively blocks epithelial calcium-activated chloride channels. (1996) (95)
- Pharmacological correction of a defect in PPARγ signaling ameliorates disease severity in Cftr-deficient mice (2010) (92)
- Acetoxymethyl esters of phosphates, enhancement of the permeability and potency of cAMP. (1993) (89)
- Nonmitogenic actions of growth factors: an integrated view of their role in intestinal physiology and pathophysiology. (1997) (86)
- Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea. (2017) (83)
- Differing effects of apical and basolateral adenosine on colonic epithelial cell line T84. (1989) (82)
- Immune-related intestinal Cl- secretion. I. Effect of histamine on the T84 cell line. (1988) (79)
- AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function* (2009) (77)
- The Role of Ion Transporters in the Pathophysiology of Infectious Diarrhea (2018) (74)
- Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon. (1995) (73)
- Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line. (1990) (67)
- Gs Protein-coupled Receptor Agonists Induce Transactivation of the Epidermal Growth Factor Receptor in T84 Cells (2004) (65)
- Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships. (2007) (65)
- Varied role of the gut epithelium in mucosal homeostasis (2007) (64)
- Modulation of chloride secretory responses and barrier function of intestinal epithelial cells by the Salmonella effector protein SigD. (2004) (63)
- Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells. (1995) (62)
- Effects of quercetin on epithelial chloride secretion. (1997) (62)
- Elevation of inositol tetrakisphosphate parallels inhibition of Ca(2+)-dependent Cl- secretion in T84 cells. (1993) (61)
- Epidermal growth factor partially restores colonic ion transport responses in mouse models of chronic colitis. (2005) (60)
- Role of Na/Ca 2 exchange in regulating cytosolic Ca 2 in cultured human pulmonary artery smooth muscle cells (2005) (60)
- Should We Divide Crohn's Disease Into Ileum-Dominant and Isolated Colonic Diseases? (2019) (57)
- Activation by calcium alone of chloride secretion in T84 epithelial cells (1993) (56)
- 5-HT induces duodenal mucosal bicarbonate secretion via cAMP- and Ca2+-dependent signaling pathways and 5-HT4 receptors in mice. (2004) (56)
- Bowditch lecture. Integrated regulation of intestinal epithelial transport: intercellular and intracellular pathways. (1997) (56)
- A Role for Protein Kinase Cε in the Inhibitory Effect of Epidermal Growth Factor on Calcium-stimulated Chloride Secretion in Human Colonic Epithelial Cells* (2000) (55)
- Functional characteristics of mucosal and connective tissue mast cells of man, the rat and other animals. (1985) (55)
- p38 mitogen-activated protein kinase inhibits calcium-dependent chloride secretion in T84 colonic epithelial cells. (2003) (54)
- Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells. (1985) (51)
- New ways of thinking about (and teaching about) intestinal epithelial function. (2008) (50)
- Calcium-sensing receptor modulates extracellular Ca(2+) entry via TRPC-encoded receptor-operated channels in human aortic smooth muscle cells. (2011) (50)
- Prolonged interferon-gamma exposure decreases ion transport, NKCC1, and Na+-K+-ATPase expression in human intestinal xenografts in vivo. (2004) (49)
- SDF-1/CXCL12 regulates cAMP production and ion transport in intestinal epithelial cells via CXCR4. (2004) (49)
- Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis. (2013) (49)
- Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia* (2016) (46)
- Cloning, expression, signaling mechanisms, and membrane targeting of P2Y(11) receptors in Madin Darby canine kidney cells. (2001) (46)
- ErbB2 and ErbB3 Receptors Mediate Inhibition of Calcium-dependent Chloride Secretion in Colonic Epithelial Cells* (1999) (45)
- Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol. (2001) (44)
- Modulation of Intestinal Barrier Properties by Probiotics: Role in Reversing Colitis (2009) (44)
- Immune-related intestinal chloride secretion. III. Acute and chronic effects of mast cell mediators on chloride secretion by a human colonic epithelial cell line. (1991) (43)
- Interferon-γ activates EGF receptor and increases TGF-α in T84 cells: implications for chloride secretion (2002) (41)
- Inhibition of IgE-mediated mast cell degranulation by sulphasalazine. (1985) (40)
- Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility. (1994) (38)
- Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction (2014) (38)
- Na(+)/Ca(2+) exchange regulates Ca(2+)-dependent duodenal mucosal ion transport and HCO(3)(-) secretion in mice. (2005) (37)
- Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway. (2005) (36)
- Nod‐like receptors are critical for gut–brain axis signalling in mice (2019) (36)
- The immune response to nematode parasites: modulation of mast cell numbers and function during Strongyloides stercoralis infections in nonhuman primates. (1988) (35)
- Detection of viruses and body fluids which may contain viruses in the domestic environment (1998) (35)
- Expression of acid‐sensing ion channels in intestinal epithelial cells and their role in the regulation of duodenal mucosal bicarbonate secretion (2011) (35)
- Dual effects of a phorbol ester on calcium-dependent chloride secretion by T84 epithelial cells. (1992) (35)
- Regulation of Chloride Secretion: Novel Pathways and Messengers (2000) (35)
- Salmonella Infection Induces a Hypersecretory Phenotype in Human Intestinal Xenografts by Inducing Cyclooxygenase 2 (2003) (33)
- The mucosal mast cell and its role in gastrointestinal allergic diseases (1984) (33)
- Heat‐stable enterotoxin of Escherichia coli (STa) can stimulate duodenal HCO3− secretion via a novel GC‐C‐ and CFTR‐independent pathway (2008) (32)
- Consequences of Direct Versus Indirect Activation of Epidermal Growth Factor Receptor in Intestinal Epithelial Cells Are Dictated by Protein-tyrosine Phosphatase 1B* (2007) (31)
- Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. (2001) (30)
- Studies on histamine secretion from enzymically dispersed cutaneous mast cells of the rat. (1985) (30)
- Cytokines: sources, receptors and signalling. (1996) (28)
- The histologic and functional characterization of enzymatically dispersed intestinal mast cells of nonhuman primates: effects of secretagogues and anti-allergic drugs on histamine secretion. (1985) (27)
- Inhibition of Ca(2+)-dependent Cl- secretion in T84 cells: membrane target(s) of inhibition is agonist specific. (1998) (27)
- A prebiotic fructo-oligosaccharide promotes tight junction assembly in intestinal epithelial cells via an AMPK-dependent pathway. (2020) (25)
- Upregulation of activin signaling in experimental colitis. (2009) (25)
- Histamine release from rodent and human mast cells induced by protoporphyrin and ultraviolet light: studies of the mechanism of mast‐cell activation in erythropoietic protoporphyria (1990) (25)
- CHAPTER 76 – Integrative Physiology and Pathophysiology of Intestinal Electrolyte Transport (2006) (25)
- Heterogeneity of mast cells in the tissues of the respiratory tract and other organ systems. (1987) (24)
- Interferon-γ Alters Downstream Signaling Originating from Epidermal Growth Factor Receptor in Intestinal Epithelial Cells (2011) (24)
- 5‐Hydroxytryptamine contributes significantly to a reflex pathway by which the duodenal mucosa protects itself from gastric acid injury (2006) (24)
- Growth hormone reduces chloride secretion in human colonic epithelial cells via EGF receptor and extracellular regulated kinase. (2003) (24)
- Dual role for AlF4(-)-sensitive G proteins in the function of T84 epithelial cells: transport and barrier effects. (1997) (23)
- Mast cells are not essential to inflammation in murine model of colitis (1994) (23)
- Decoding epithelial signals: critical role for the epidermal growth factor receptor in controlling intestinal transport function (2009) (23)
- Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera (2018) (23)
- Transactivation of the epidermal growth factor receptor mediates muscarinic stimulation of focal adhesion kinase in intestinal epithelial cells (2005) (22)
- New insights into the pathogenesis of intestinal dysfunction: secretory diarrhea and cystic fibrosis. (2000) (22)
- Epithelial transport and gut barrier function in colitis (2003) (21)
- The cystic fibrosis gene. (1990) (21)
- Differential effects of apical and basolateral uridine triphosphate on intestinal epithelial chloride secretion. (2001) (20)
- A role for guanylate cyclase C in acid-stimulated duodenal mucosal bicarbonate secretion. (2004) (20)
- A comparison of histamine secretion from isolated peritoneal mast cells of the mouse and rat. (1983) (19)
- Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion. (2002) (19)
- Mast cell heterogeneity: Evidence and implications (1984) (19)
- A role for protein kinase cepsilon in the inhibitory effect of epidermal growth factor on calcium-stimulated chloride secretion in human colonic epithelial cells. (2000) (19)
- Phosphatidylinositol 3-Kinase-dependent Pathways Oppose Fas-induced Apoptosis and Limit Chloride Secretion in Human Intestinal Epithelial Cells (2001) (19)
- Inhibition of rabbit duodenal bicarbonate secretion by ulcerogenic agents: histamine-dependent and -independent effects. (1998) (18)
- Utility of endoscopic biopsy samples to quantitate human duodenal ion transport. (1998) (17)
- Apical leptin induces chloride secretion by intestinal epithelial cells and in a rat model of acute chemotherapy-induced colitis. (2010) (17)
- Phosphatidic acid modulates Cl- secretion in T84 cells: varying effects depending on mode of stimulation. (1993) (17)
- Carbachol Stimulates Transactivation of Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase in T84Cells (1998) (17)
- The effects of aspartame on mast cells and basophils. (1986) (17)
- Interleukin 9 Alters Epithelial Barrier and E-cadherin in Eosinophilic Esophagitis (2019) (16)
- Hydrogen peroxide inhibits Ca2+‐dependent chloride secretion across colonic epithelial cells via distinct kinase signaling pathways and ion transport proteins (2008) (16)
- Gastrointestinal transport : molecular physiology (2001) (16)
- Potentiation of calcium‐activated chloride secretion and barrier dysfunction may underlie EGF receptor tyrosine kinase inhibitor‐induced diarrhea (2020) (16)
- Bradykinin regulates human colonic ion transport in vitro (2008) (16)
- Pharmacological aspects of therapy in inflammatory bowel diseases: antidiarrheal agents. (1988) (16)
- Hydroxylases regulate intestinal fibrosis through the suppression of ERK mediated TGF-β1 signaling. (2016) (15)
- Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea. (2013) (15)
- Dual effects of protoporphyrin and long wave ultraviolet light on histamine release from rat peritoneal and cutaneous mast cells. (1990) (15)
- Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. (2015) (14)
- Mast cells isolated from guinea-pig lung: characterization and studies on histamine secretion (1983) (14)
- Histamine inhibits prostaglandin E2-stimulated rabbit duodenal bicarbonate secretion via H2 receptors and enteric nerves. (1995) (14)
- Mast cell heterogeneity in higher animals: a comparison of the properties of autologous lung and intestinal mast cells from nonhuman primates. (1986) (14)
- Electrolyte secretion and absorption in the small intestine and colon (2009) (14)
- A comparative study of histamine secretion from rat peritoneal and pleural mast cells (1982) (13)
- Endogenous and exogenous control of gastrointestinal epithelial function: building on the legacy of Bayliss and Starling (2017) (13)
- Hydrogen peroxide scavenger, catalase, alleviates ion transport dysfunction in murine colitis (2016) (13)
- Protein kinase C potentiates cAMP-stimulated mouse duodenal mucosal bicarbonate secretion in vitro. (2004) (12)
- Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy. (2019) (12)
- Effect of Histamine and Other Mast Cell Mediators on T84 Epithelial Cells a (1992) (12)
- Bioactivatable derivatives of 8-substituted cAMP-analogues (1997) (11)
- Comprar Ganong's Physiology Examination And Board Review | Kim Barrett | 9780071832328 | MCGRAW HILL (2017) (11)
- T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling. (2021) (11)
- Protection of epithelial barrier function by the Crohn ' s disease associated gene , protein tyrosine phosphatase N 2 Short Title : Epithelial barrier protection by PTPN 2 (2010) (10)
- TGFβ1 Single Nucleotide Polymorphism C-509T Alters Mucosal Cell Function in Pediatric Eosinophilic Esophagitis (2019) (10)
- Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells. (2001) (10)
- A Role for CagA/VacA in Helicobacter pylori Inhibition of Murine Duodenal Mucosal Bicarbonate Secretion (2004) (10)
- Inhibition of human peripheral blood lymphocyte function by protoporphyrin and longwave ultraviolet light. (1994) (10)
- Effect of the diglyceride lipase inhibitor, RG80267, on epithelial chloride secretion induced by various agents. (1995) (9)
- Cross-Talk between Calcium and cAMP-dependent Intracellular Signaling Pathways (9)
- Probiotic inhibition of the entry of enteroinvasive E. coli into, human intestinal epithelial cells involves both Rho-dependent and -independent pathways (2003) (9)
- Epithelial biology in the gastrointestinal system: insights into normal physiology and disease pathogenesis (2012) (9)
- A new twist on trefoils. Focus on “TFF3 modulates NF-κB and a novel regulatory molecule of NF-κB in intestinal epithelial cells via a mechanism distinct from TNF-α” (2005) (9)
- Altered chloride secretory responses in HT29/Cl.19A cells infected with giardia lamblia (2000) (9)
- Promoting physiology as an essential element in translational research. (2012) (9)
- Na /Ca exchange regulates Ca -dependent duodenal mucosal ion transport and HCO3 secretion in mice (2005) (8)
- Protein kinase C activity does not mediate the inhibitory effect of carbachol on chloride secretion by T84 cells. (1994) (8)
- Where we're going . . . (1998) (8)
- Congenital Tufting Enteropathy-Associated Mutant of Epithelial Cell Adhesion Molecule Activates the Unfolded Protein Response in a Murine Model of the Disease (2020) (8)
- Mast cells, basophils, and immunoglobulin E. (1996) (8)
- Role of protein phosphatase 2A in calcium-dependent chloride secretion by human colonic epithelial cells. (2007) (7)
- Reports of physiology's demise have been greatly exaggerated. (2013) (7)
- Hypertonic saline reduces neutrophil-epithelial interactions in vitro and gut tissue damage in a mouse model of colitis. (2008) (7)
- Chloride Secretion by the Colonic Epithelial Cell Line T84: Mechanisms and Regulation (1993) (7)
- Building better bugs to deliver biologics in intestinal inflammation (2010) (7)
- Claudin-2 pore causes leak that breaches the dam in intestinal inflammation. (2020) (7)
- Histamine secretion induced byN-acetyl cysteine (1985) (7)
- Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected]. (2016) (7)
- Preparing your curriculum vitae. (2002) (7)
- Epithelial transport in digestive diseases - mice, monolayers and mechanisms: 2019 Hans Ussing Distinguished Lecture Article. (2020) (6)
- Report from the Information Overload and Underload Workgroup (2016) (6)
- Modulation of human cutaneous mast cell responsiveness by a single, low-dose, PUVA treatment. (1991) (6)
- A new twist on trefoils. Focus on "TFF3 modulates NF-{kappa}B and a novel regulatory molecule of NF-{kappa}B in intestinal epithelial cells via a mechanism distinct from TNF-{alpha}". (2005) (6)
- Inhibition of mast cell mediator secretion induced by protoporphyrin plus long-wave ultraviolet light: a morphometric and ultrastructural analysis. (1994) (6)
- Comparison of early signaling events and physiological consequences in Salmonella typhimurium-and typhi-infected intestinal epithelial cells (2003) (5)
- Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF- (cid:2) 1 signaling (2018) (5)
- Intestinal epithelial secretion and barrier function: from bench to bedside (2005) (5)
- Buku Ajar Fisiologi Kedokteran Ganong (2015) (5)
- Influence of the microbiota on host physiology – moving beyond the gut (2017) (5)
- Chapter 7 Integrated signaling mechanisms that regulate intestinal chloride secretion (2000) (5)
- Histamine release from the cultured mouse mast cell line PT 18 in response to immunologic and non-immunologic stimuli (1984) (5)
- An epithelial mucin may protect the epithelium from inflammatory damage. (1991) (5)
- The world within – impact of the intestinal micobiota on whole body physiology and pathophysiology (2009) (5)
- Provisional atlas of the insects of the British Isles. Part 5 Hymenoptera: Formicidae Ants. 1st ed (1977) (5)
- Neurogenic inflammation in the intestine. (1995) (4)
- Bidirectional communication between mast cells and nerves controls intestinal secretion. (1991) (4)
- Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy (2020) (4)
- Histamine secretion from mast cells treated with chlortetracycline (aureomycin): a novel calcium ionophore (1983) (4)
- Rethinking cholera pathogenesis- No longer all in the same "camp". (2016) (4)
- Protoporphyrin and long-wave ultraviolet light modulate metabolic events in rat peritoneal mast cells. (1992) (4)
- Reproducibility and data presentation (2019) (4)
- AMP and microamps: neutrophil-derived chloride secretagogue identified. (1993) (3)
- Calcium-mediated chloride secretion in the intestinal epithelium: Significance and regulation (2002) (3)
- Adhesion molecule expression in inflammatory bowel disease. (1993) (3)
- A personal perspective (1996) (3)
- How can we battle the scourge of diarrhea? 2003 McKenna Memorial Lecture. (2003) (3)
- The ability of protoporphyrin plus long-wave ultraviolet light to inhibit calcium mobilization and mediator release in mast cells is not related to changes in phospholipid signaling pathways. (1991) (3)
- Increased expression of nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) is associated with enhanced chloride secretion in cells infected with enteroinvasive bacteria (2000) (3)
- Alterations in Fc epsilon RI induced by protoporphyrin plus long-wavelength ultraviolet light in mouse bone marrow-derived mast cells. (1993) (3)
- Information Overload and Underload (2016) (3)
- Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells. (1998) (3)
- EPITHELIUM: Molecular Basis and Regulatory Aspects (2000) (3)
- Mechanisms of mast cell signaling (1993) (3)
- Ganong's medical physiology examination and board review (2018) (3)
- Carbachol transactivation of the EGF receptor in T34 cells requires TGF-α release (2001) (3)
- SDF-1 / CXCL 12 regulates cAMP production and ion transport in intestinal epithelial cells via CXCR 4 (2004) (3)
- IgE and adenosine 5' triphosphate receptors on immature murine mast cells are functionally linked to signal transduction mechanisms. (1992) (3)
- Differential effects of uridine triphosphate on intestinal chloride secretion depending on side of addition: Implications for cystic fibrosis therapy (1998) (3)
- Towards gender equality in scientific careers: Are we there yet? … Are we there yet? … Are we there yet? (2019) (3)
- Binding of human IgE to rodent mast cells and basophils (1985) (2)
- HIV protein gp 120 and chemokines receptor for liver fibrosis (2010) (2)
- Bactericidal activity of mast cells. (1994) (2)
- T1065 Expression and Function of Acid-Sensing Ion Channels in Intestinal Epithelial Cells (2008) (2)
- Mechanisms of inflammatory diarrhea. (1992) (2)
- The effect of a fennel seed extract on the STAT signaling and intestinal barrier function (2022) (2)
- Mast cells and duodenal bicarbonate secretion (1998) (2)
- An enteric pathogen subverts epithelial signal transduction mechanisms for invasion. (1993) (2)
- Intestinal secretory mechanisms and diarrhea. (2022) (2)
- Modulation of tight junction (TJ) structure by enteroinvasive E. coli (EIEC) is prevented by H2O2 scavengers and protein kinase C(PKC) inhibitors (2001) (2)
- Diarrhoeal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signalling (2022) (2)
- Natural history of colitis and associated epithelial dysfunction in conventionally housed Mdrla-/-mice (2003) (2)
- Colonic epithelial ErbB2 receptors: A possible role in diversification of inhibitory signaling via the EGF receptor (1998) (2)
- Differential effects of anti-allergic compounds on peritoneal mast cells of the rat, mouse and hamster (1984) (2)
- Success as a PhD in Gastroenterology. (2012) (2)
- Neuroimmune regulation of human intestinal transport. (1993) (2)
- Fostering Sustainable Biomedical Research Training in Mozambique: A Spin-Off of the Medical Education Partnership Initiative (2022) (2)
- New frontiers in gastrointestinal physiology and pathophysiology (2018) (2)
- Acute Treatment of Isolated Colon with The Hydrogen Peroxide Scavenger, Catalase, Alleviates Ion Transport Dysfunction in Murine DSS Colitis (2008) (1)
- Fibroblast growth promoted by a mast cell protease. (1992) (1)
- Promotion & Tenure Reform Workgroup Report (2017) (1)
- P-188 Nod Receptors Modulate the Microbiota-Gut-Brain Axis (2016) (1)
- Role of Salmonella effector proteins SipB and SipC in altered barrier and transport properties of human intestinal epithelium (2003) (1)
- Mitogens control Na+/H+ antiporter activity by phosphorylation. (1990) (1)
- Mapping the Duodenal Crypt-Villus Transport Axis (2018) (1)
- Allergic reactions alter gastric function. (1990) (1)
- Microcirculation in the perfused limb: 348 (1997) (1)
- Carbachol activates p38 MAP kinase in T84 cells: Implications for carbachol-stimulated chloride secretion (2000) (1)
- The yin and yang of intestinal differentiation: key roles for lipid signaling. (2001) (1)
- Martin F. Kagnoff, MD: 1941–2014 (2015) (1)
- Complex cellular recognition events in acute inflammation. (1992) (1)
- Fr587 SALMONELLA BIASES INTESTINAL EPITHELIAL DIFFERENTIATION THROUGH WNT AND NOTCH SIGNALING, THUS POSSIBLY CONTRIBUTING TO ITS DIARRHEAL PATHOGENESIS (2021) (1)
- Something old, something new. (1999) (1)
- Acute activation of Gq protein-coupled receptors elicits chronic inhibition of colonic epithelial Cl− secretion (2003) (1)
- Salmonella dublin infection inhibits chloride secretion in T84 cells (2000) (1)
- Rotavirus infection induces increased chloride secretion, altered barrier function and epidermal growth factor receptor (EGF-R) polyubiquitination in intestinal epithelial cells (IEC) (2001) (1)
- Central regulation of duodenal bicarbonate secretion. (1990) (1)
- Reporting of studies using animal and human subjects in APS journals: how the society protects authors from ethical minefields. (2012) (1)
- Enhanced tissue responsiveness in colonic ion transport of cow's milk-sensitized guinea pigs (1994) (1)
- Potentially probiotic Limosilactobacillus reuteri from human milk strengthens the gut barrier in T84 cells and a murine enteroid model. (2022) (1)
- Human intestinal xenografts as a new model for ion transport studies (2000) (1)
- DRAwing Conclusions About the Basis of Diarrhea in Inflammatory Bowel Disease (2020) (1)
- Nod-like receptors are critical for gut-brain axis signaling (2019) (1)
- The host engulfment pathway in enteroids is linked to intestinal inflammation following bacterial infection (2017) (1)
- Nod1/Nod2 Receptors Modulate the Microbiota‐Gut‐Brain Axis (2015) (1)
- 353 Comparison of the effects of anti-allergic drugs on monkey lung and intestinal mast cells (1985) (1)
- Congratulations, APS! 125 and counting … (2012) (1)
- Antibiotics versus probiotic treatments in the mdr1a −/− mouse model of colitis (2006) (1)
- Hydroxylase inhibition reduces transforming growth factor‐β1 induced fibrosis associated with colitis (2016) (1)
- Mechanisms for amplified mediator release from colonic mast cells: implications for intestinal inflammatory diseases. (2004) (1)
- Cytokine Interactions with Epithelium (1996) (1)
- Heregulin inhibits calcium-dependent chloride secretion: A role for ErbB2 and ErbB3 (1998) (1)
- Guanylate cyclase C (GC-C) mediates acid-stimulated duodenal mucosal bicarbonate secretion (DMBS) (2001) (1)
- Posthumous presentation of the Julius M. Friedenwald medal to Jon I. Isenberg, M.D. (2004) (1)
- In Memoriam: Alan F. Hofmann, MD, PhD, May 17, 1931, to September 7, 2021. (2022) (1)
- Tu1979 Probiotics Can Normalize the Gut-Brain Axis in Immunodeficient Mice (2013) (1)
- Thank you to reviewers (2019) (0)
- Report on the Women in Physiology Symposium in IUPS 2009 (2010) (0)
- Tu1693 – Potentiation of Calcium-Activated Chloride Secretion and Barrier Dysfunction May Underlie the Ability of Epidermal Growth Factor-Directed Tyrosine Kinase Inhibitors to Induce Diarrhea (2019) (0)
- Protein phosphatase 2A participates in effect of epidermal growth factor on phosphatidylinositol 3-kinase: Role in ion transport (2001) (0)
- O-027 PTPN2 Deficiency Exacerbates Epithelial Barrier Dysfunction in vivo and in vitro via Redistribution of Occludin and ZO-1 (2013) (0)
- Translational Research Promoting Physiology as an Essential Element in (2015) (0)
- Increased ion transport is due to upregulated cyclooxygenase activity in Salmonella infected human intestinal xenografts (2001) (0)
- triphosphate on intestinal epithelial chloride secretion Differential effects of apical and basolateral uridine (2016) (0)
- Epidermal growth factor, transforming growth factor-α, and carbachol display differences in specific epidermal growth factor receptor tyrosine residue phosphorylation, and dependence on PI3-kinase to inhibit chloride secretion (2003) (0)
- Mo1758 Knock-Down of the Congenital Tufting Enteropathy Gene, Epcam, Results in Barrier and Ion Transport Dysfunction in Intestinal Epithelial Cells (2014) (0)
- Hypertonic saline inhibits mucosal inflammatory events in vitro and in vivo (2005) (0)
- A new target to treat diarrhea in cholera? (2019) (0)
- 129 The Crohn's Disease Candidate Gene Protein Tyrosine Phosphatase N2 (PTPN2) Is Activated By Gamma Interferon (IFNγ) in Intestinal Epithelial Cells (IECs) in An Adenosine-Monophosphate Kinase (Ampk) Dependent Manner (2008) (0)
- A Role for Protein Kinase Ce in the Inhibitory Effect of Epidermal Growth Factor on Calcium-stimulated Chloride Secretion in Human Colonic Epithelial Cells* (2000) (0)
- Modulation and function of mucosal mast cells in parasitic infections of monkeys (1985) (0)
- Faculty Opinions recommendation of Multidrug resistance gene deficient (mdr1a-/-) mice have an altered caecal microbiota that precedes the onset of intestinal inflammation. (2009) (0)
- cAMP stimulates protein typosine phosphorylation in T84 epithelial cells: Implications for CAMP-dependent chloride secretion (1998) (0)
- M1699 Protein Tyrosine Phosphatase N2 (PTPN2) Knock-Down Aggravates Interferon Gamma (IFNγ) -Induced Intestinal Epithelial Barrier Dysfunction via Upregulation of Claudin-2 (2009) (0)
- Synergism between vasoactive intestinal polypeptide and carbachol-mediated responses in a human mucus-secreting colonic epithelial cell line. (1989) (0)
- Leonard R.JohnsonPhysiology of the Gastrointestinal Tract, 5th edition2012Academic PressNew York, New York97801238202662312 pp. $500.00. Web address for ordering: www.elsevier.com (2013) (0)
- How enterocytes stick and what they stick to. (1991) (0)
- Acknowledgment of 2008 Reviewers (2009) (0)
- Gastrointestinal jabberwocky to bioengineering design: using function diagrams to teach physiology. (2021) (0)
- Chlorpromazine derivatives: agents that modify signal transduction mechanisms in intestinal secretion. (1989) (0)
- Faculty Opinions recommendation of Attaching and effacing pathogen-induced tight junction disruption in vivo. (2006) (0)
- intestinal inflammation Building better bugs to deliver biologics in (2010) (0)
- Interferon-γ regulates epithelial chloride secretion: Role of EGF receptor-dependent pathways (1998) (0)
- Direct and indirect signaling through the epidermal growth factor receptor (EGFr) exerts distinct effects on surface expression of Na+, K+, 2 Cl− cotransporter‐1 (NKCC1) in colonic epithelial cells (2009) (0)
- 86th President of APS. (2013) (0)
- Faculty Opinions recommendation of Intestinal mucosal alterations in rats with carbon tetrachloride-induced cirrhosis: changes in glycosylation and luminal bacteria. (2006) (0)
- Muscarinic stimulation of focal adhesion kinase is mediated by epidermal growth factor receptor transactivation in T34 epithelial cells (2001) (0)
- Sa1775 Salmonella Typhimurium Infection Alters Cell Fate During Differentiation of Intestinal Epithelium (2015) (0)
- 745 Hydrogen Peroxide Inhibits CA2+-Stimulated Colonic Epithelial Ion Transport Via Activation of Adenosine Monophosphate-Activated Protein Kinase and Inhibition of NKCC1 (2008) (0)
- intestinal epithelial function New ways of thinking about (and teaching about) (2015) (0)
- The future of pediatric research looks bright. (2001) (0)
- Getting your first paper published – shedding light on unwritten rules (2018) (0)
- Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by the Nuclear Bile Acid Receptor, Farnesoid X Receptor (2022) (0)
- Faculty Opinions recommendation of Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. (2006) (0)
- How Diversity is Becoming a Reality in the American Physiological Society. (2015) (0)
- Autonomic Regulation of Cardiovascular Function in Health and Disease MEETING PROGRAM (2011) (0)
- Loosening the ties that bind--novel strategy to enhance oral bioavailability. (2003) (0)
- The Effect of Fennel (Foeniculum vulgare) on the JAK/STAT Pathway and Intestinal Barrier Function (2018) (0)
- Intestinal Epithelial Barrier Function-induced Decrease in γ the Interferon-AMP-activated Protein Kinase Mediates Mechanisms of Signal Transduction : (2009) (0)
- M1203 Synbiotics Modulate Intestinal Epithelial-Dendritic Cell Interactions in the Mdr1a-/- Mouse Model of Colitis: Role in Prevention of Disease (2008) (0)
- Na /Ca 2 exchange regulates Ca 2 (cid:1) -dependent duodenal mucosal ion transport and HCO 3 (cid:2) secretion in mice (2005) (0)
- W1163 Activin Signaling in Experimental Colitis (2008) (0)
- PGE2-Stimulated human duodenal epithelial bicarbonate secretion involves MAPK (ERK) Activation (2001) (0)
- Stress and the gut – it’s not all in your mind: How interactions between the brain, the gastrointestinal system, and the microbial residents of the gut influence both gastrointestinal and cognitive function (2017) (0)
- Role of the microbiota-gut-brain axis in postacute COVID syndrome (2023) (0)
- Reflecting on a year of change and the year ahead (2017) (0)
- Reddit ‘Ask me Anything’ (AMA) with Kim Barrett (2017) (0)
- Faculty Opinions recommendation of Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. (2013) (0)
- Counter‐regulation of the HIF‐dependent adaptive response to hypoxia by hypercapnia (2016) (0)
- A Pathobiont Fragments Mitochondrial Networks in Epithelial Cells: Implications for Crohn’s Disease (2020) (0)
- Mucus and metastasis. (1992) (0)
- Hydrogen peroxide inhibits colonic epithelial ion transport by MAP kinase and PI3‐kinase (PI3K) independently of activated epidermal growth factor receptor (EGFr) (2006) (0)
- 754 Altered Expression and Localization of Colonic Ion Transporters in a Mouse Model of Salmonella-Induced Diarrhea (2012) (0)
- p 38 mitogen-activated protein kinase inhibits calcium-dependent chloride secretion in T 84 colonic epithelial cells (2002) (0)
- Specific regulation of a mucosal addressin. (1994) (0)
- Faculty Opinions recommendation of Production of a Functional Factor, p40, by Lactobacillus rhamnosus GG Is Promoted by Intestinal Epithelial Cell-Secreted Extracellular Vesicles. (2019) (0)
- Mast cell and basophil responses (1993) (0)
- Faculty Opinions recommendation of Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability. (2006) (0)
- Inhibition of Adenosine Monophosphate‐activated Protein Kinase (AMPK) ameliorates the effects of Interferon gamma (IFN gamma) on epithelial barrier function in T84 cells (2008) (0)
- Faculty Opinions recommendation of Antisecretory effects of neuropeptide Y in the mouse colon are region-specific and are lost in DSS-induced colitis. (2010) (0)
- Faculty Opinions recommendation of Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis. (2014) (0)
- W1653 Protein Tyrosine Phosphatase N2 (PTPN2) Knock-Down Suppresses Epithelial Ion Transport By Promoting Epidermal Growth Factor (EGF) -Induced EGF-Receptor (EGFR) and Phosphatidylinositol 3'-Kinase (PI3-K) Activation (2009) (0)
- More news on the cystic fibrosis gene. (1991) (0)
- Interferon‐gamma (IFN γ) induced epithelial barrier dysfunction in T84 human intestinal epithelial cells (IECs) occurs via phosphatidylinositol 3‐kinase (PI3‐K) mediated activation of adenosine monophosphate‐activated protein kinase (AMPK) (2009) (0)
- Acknowledgment of 2009 Reviewers (2010) (0)
- Journal Editor Stakeholders Report (2017) (0)
- Meeting notes: Epithelia and Membrane Transport Symposium (2019) (0)
- Faculty of 1000 evaluation for A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? (2012) (0)
- Thank you to reviewers (2005) (0)
- Thank you to reviewers (2018) (0)
- Thank you to reviewers (2009) (0)
- BOOK REVIEWS (2006) (0)
- Faculty of 1000 evaluation for Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. (2018) (0)
- Reduced Expression of Down‐Regulated in Adenoma (DRA) in Murine Enteroid‐Derived Monolayers Following Infection with Salmonella (2017) (0)
- Research Agenda for Pediatric Gastroenterology, Hepatology and Nutrition: Secretion and Diarrhea: Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition Foundation (2002) (0)
- Subtraction gives 13: novel cytokine identified. (1993) (0)
- APS leadership meets with NIGMS. (2014) (0)
- Physiological Regulation of Gastrointestinal Ion Transport (2003) (0)
- Looking to and nurturing the future of physiology (2017) (0)
- Impact of Probiotics on Communication between the Brain-Gut: Implications for the Treatment of the Psychological Effects of Digestive Disease States (2018) (0)
- New messenger for calcium entry. (1993) (0)
- Hydrogen peroxide inhibits carbachol‐stimulated colonic epithelial ion transport by adenosine monophosphate‐activated protein kinase activation, without abolishing carbachol‐stimulated Ca2+ signal (2007) (0)
- Faculty Opinions recommendation of Glucocorticoids regulate barrier function and claudin expression in intestinal epithelial cells via MKP-1. (2013) (0)
- Microcompetition with Foreign DNA and the Origin of Chronic Disease (reivew) (2005) (0)
- Administration of Probiotics Normalizes Deficits in the Microbiota‐Gut‐Brain Axis Induced by DSS‐Colitis (2015) (0)
- Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation (2022) (0)
- Faculty Opinions recommendation of Manganese blocks intracellular trafficking of Shiga toxin and protects against Shiga toxicosis. (2012) (0)
- 736 MUTANT EPCAM MODEL OF CONGENITAL TUFTING ENTEROPATHY SHOWS ABERRANT INTESTINAL EPITHELIAL CELL DIFFERENTIATION (2020) (0)
- The Effect of a Fennel Extract on the STAT Signaling and Intestinal Barrier Function (2021) (0)
- Guest Editorial (2014) (0)
- Faculty Opinions recommendation of P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis. (2011) (0)
- Presentation of the Julius M. Friedenwald Medal to Gail A. Hecht. (2020) (0)
- Nutraceutical targeting of the bile acid receptor, farnesoid X receptor, for intestinal disease (2022) (0)
- Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function (2022) (0)
- Something old, something new. (1999) (0)
- Faculty Opinions recommendation of The role of rectal chloride secretion in childhood constipation. (2012) (0)
- The end of an era (2022) (0)
- T1081 Effect of Lubiprostone On Duodenal Mucosal Bicarbonate Secretion (2008) (0)
- Changing of the Guard (2016) (0)
- 570 In Vivo PTPN2-Deficiency and a Dominant-Negative PTPN2 Mutation Cause Increased Intestinal Permeability and Alter Tight Junction Composition (2014) (0)
- Intestinal Transport Defects in a Mouse Model of Salmonella-Induced Diarrhea (2011) (0)
- Thank You to Reviewers (1996) (0)
- Faculty Opinions recommendation of Age-associated remodeling of the intestinal epithelial barrier. (2013) (0)
- Review of Medical Physiology (1964) (0)
- The precipitation of behavioral defects due to inflammation in the DSS mouse model of colitis (LB748) (2014) (0)
- Protein kinase C subspecies. (1989) (0)
- JAK2 mediates the negative regulation of calcium-dependent chloride secretion by growth hormone in human colonic epithelial cells (2003) (0)
- Exploratory Testing of a New Well-Logging Technique (1966) (0)
- Chronobiology Q&A with our journals’ Editors-in-Chief (2019) (0)
- Susceptibility antibiotic screening reveals high rates of multidrug resistance of Salmonella, Shigella and Campylobacter in HIV infected and uninfected patients from Mozambique (2023) (0)
- Mast cell heterogeneity in non-human primates (1986) (0)
- Gastrointestinal (GI) Physiology (2014) (0)
- Faculty Opinions recommendation of VSL#3 probiotic treatment reduces chemotherapy-induced diarrhea and weight loss. (2007) (0)
- FUNCTIONAL-HETEROGENEITY OF MAST-CELLS, WITH SPECIAL REFERENCE TO THE GASTROINTESTINAL-TRACT (1984) (0)
- Su1592: EFFECT OF PEDIATRIC IBD-ASSOCIATED COMMENSAL BACTERIA ON EPITHELIAL BARRIER FUNCTION (2022) (0)
- Faculty Opinions recommendation of Intestinal epithelial autophagy is essential for host defense against invasive bacteria. (2013) (0)
- Protein kinase CE mediates the inhmitory effect of epidermal growth factor on carbachol-induced chloride secretion in T84 epithelial cells (2000) (0)
- A joy for (the science of) life! (2014) (0)
- Decreased ion transport and NKCC-1 levels in interferon-gamma treated human intestinal xenografts (2001) (0)
- Salmonella biases epithelial differentiation in murine enteroids through Wnt and Notch signaling, which may contribute to diarrheal pathogenesis (2020) (0)
- Faculty Opinions recommendation of Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress. (2006) (0)
- S1779 Inflammation Modulates the Recruitment of Signaling Pathways Downstream of the EGF Receptor in Colonic Epithelial Cells (2008) (0)
- PI3'-kinase- and fas-dependent pathways regulate apoplosis, barrier function and chloride secretion in intestinal epithelial cells (IEC): Implications for inflammatory diarrheal states (2001) (0)
- Faculty Opinions recommendation of Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. (2010) (0)
- Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction (2014) (0)
- W1572 Involvement of Nodal and Lefty Signaling in Intestinal Crypt Cell Growth (2009) (0)
- Su1246 SPECIFIC BACTERIA ISOLATED FROM HUMAN BREAST MILK BOLSTER INTESTINAL EPITHELIAL BARRIER FUNCTION, AND AMELIORATE DYSFUNCTION INDUCED BY SALMONELLA ENTERICA INFECTION (2020) (0)
- Faculty Opinions recommendation of Requirement of cellular prion protein for intestinal barrier function and mislocalization in patients with inflammatory bowel disease. (2012) (0)
- Faculty Opinions recommendation of Colonic microbiota encroachment correlates with dysglycemia in humans. (2017) (0)
- Faculty Opinions recommendation of Vasoactive intestinal peptide ameliorates intestinal barrier disruption associated with Citrobacter rodentium-induced colitis. (2009) (0)
- Exaggeratedof Physiology's Demise Have Been Greatly (2016) (0)
- Martin F. Kagnoff, MD, January 19, 1941--November 16, 2014. (2015) (0)
- Acute and Chronic Control of Colonic Chloride Secretion by Mast Cell Mediators (1993) (0)
- New Insights into Gastrointestinal and Liver Diseases Based on Molecular Aspects of Transport Physiology (2002) (0)
- S1771 Interferon-γ Selectively Modulates the Ability of EGF to Activate EGFR Signaling and Reverses Its Inhibitory Effects On K+ Channel Activity in T84 Colonic Epithelial Cells (2009) (0)
- Faculty Opinions recommendation of Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. (2008) (0)
- Faculty Opinions recommendation of Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity. (2013) (0)
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