Kim Nasmyth
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British biochemist
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Kim Nasmythbiology Degrees
Biology
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Biochemistry
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Biology
Kim Nasmyth's Degrees
- Bachelors Biochemistry University of Oxford
Why Is Kim Nasmyth Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kim Ashley Nasmyth is an English geneticist, the Whitley Professor of Biochemistry at the University of Oxford, a Fellow of Trinity College, Oxford, former scientific director of the Research Institute of Molecular Pathology , and former head of the Department of Biochemistry, University of Oxford. He is best known for his work on the segregation of chromosomes during cell division.
Kim Nasmyth's Published Works
Published Works
- Cohesins: Chromosomal Proteins that Prevent Premature Separation of Sister Chromatids (1997) (1542)
- Epitope tagging of yeast genes using a PCR‐based strategy: more tags and improved practical routines (1999) (1082)
- Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1 (1999) (1014)
- The B-type cyclin kinase inhibitor p40 SIC1 controls the G1 to S transition in S. cerevisiae (1994) (939)
- Cohesin: its roles and mechanisms. (2009) (921)
- Cleavage of Cohesin by the CD Clan Protease Separin Triggers Anaphase in Yeast (2000) (865)
- Evidence that the Ipl1-Sli15 (Aurora Kinase-INCENP) Complex Promotes Chromosome Bi-orientation by Altering Kinetochore-Spindle Pole Connections (2002) (802)
- Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis. (2001) (773)
- A Central Role for Cohesins in Sister Chromatid Cohesion, Formation of Axial Elements, and Recombination during Yeast Meiosis (1999) (759)
- Whose end is destruction: cell division and the anaphase-promoting complex. (1999) (754)
- Molecular architecture of SMC proteins and the yeast cohesin complex. (2002) (736)
- Un Ménage à Quatre The Molecular Biology of Chromosome Segregation in Meiosis (2003) (719)
- Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. (2000) (713)
- An ESP1/PDS1 Complex Regulates Loss of Sister Chromatid Cohesion at the Metaphase to Anaphase Transition in Yeast (1998) (686)
- The structure and function of SMC and kleisin complexes. (2005) (643)
- Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. (1999) (638)
- Ordered Recruitment of Transcription and Chromatin Remodeling Factors to a Cell Cycle– and Developmentally Regulated Promoter (1999) (627)
- BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals (2008) (619)
- Chromosomal Cohesin Forms a Ring (2003) (593)
- Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast (1995) (591)
- Segregating Sister Genomes: The Molecular Biology of Chromosome Separation (2002) (579)
- Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex. (1998) (575)
- CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. (1993) (550)
- The Polo‐like kinase Cdc5p and the WD‐repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae (1998) (548)
- Loading of an Mcm Protein onto DNA Replication Origins Is Regulated by Cdc6p and CDKs (1997) (545)
- Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements (1987) (534)
- Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. (1997) (527)
- Regulation of the yeast HO gene. (1985) (527)
- Control of the yeast cell cycle by the Cdc28 protein kinase. (1993) (515)
- The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15 (1991) (513)
- Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe (1976) (510)
- Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle (1994) (503)
- Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. (1993) (501)
- Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I (2006) (495)
- Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins (2010) (493)
- Cohesion between sister chromatids must be established during DNA replication (1998) (486)
- Splitting the chromosome: cutting the ties that bind sister chromatids. (2000) (477)
- The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae (1991) (457)
- Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin (2000) (454)
- The cohesin ring concatenates sister DNA molecules (2008) (452)
- Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer (1985) (441)
- Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae. (1995) (439)
- Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. (1999) (437)
- Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene. (1980) (409)
- Phosphorylation of the Cohesin Subunit Scc1 by Polo/Cdc5 Kinase Regulates Sister Chromatid Separation in Yeast (2001) (404)
- At the heart of the budding yeast cell cycle. (1996) (403)
- S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state (1995) (394)
- Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae (2001) (392)
- Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. (1995) (386)
- Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins (1993) (384)
- A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. (1993) (384)
- Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells (2005) (383)
- Asymmetric Accumulation of Ash1p in Postanaphase Nuclei Depends on a Myosin and Restricts Yeast Mating-Type Switching to Mother Cells (1996) (379)
- Viewpoint: Putting the Cell Cycle in Order (1996) (379)
- APCCdc20 promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5 (1999) (378)
- An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast (1996) (376)
- Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus (1982) (368)
- Roles and regulation of Cln‐Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. (1995) (365)
- Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators (1987) (364)
- Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation (2000) (358)
- The structure of transposable yeast mating type loci (1980) (358)
- Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. (1998) (344)
- The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast (1991) (337)
- Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila (1987) (330)
- Identification of Cohesin Association Sites at Centromeres and along Chromosome Arms (1999) (330)
- Mother Cell–Specific HO Expression in Budding Yeast Depends on the Unconventional Myosin Myo4p and Other Cytoplasmic Proteins (1996) (325)
- Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. (2009) (323)
- Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast. (1996) (321)
- Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. (1992) (320)
- Structure and stability of cohesin's Smc1-kleisin interaction. (2004) (318)
- Functional Genomics Identifies Monopolin A Kinetochore Protein Required for Segregation of Homologs during Meiosis I (2000) (310)
- Localization and sequence analysis of yeast origins of DNA replication. (1983) (305)
- Modes of spindle pole body inheritance and segregation of the Bfa1p–Bub2p checkpoint protein complex (2001) (301)
- ATP Hydrolysis Is Required for Cohesin's Association with Chromosomes (2003) (292)
- A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation (1987) (290)
- Cell cycle regulated transcription in yeast. (1994) (289)
- Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae (1992) (287)
- Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase. (2000) (285)
- Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. (1992) (283)
- Evidence that Loading of Cohesin Onto Chromosomes Involves Opening of Its SMC Hinge (2006) (281)
- A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. (2004) (280)
- Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons (2008) (280)
- Identification of Subunits of the Anaphase-Promoting Complex of Saccharomyces cerevisiae (1996) (275)
- Pds5 cooperates with cohesin in maintaining sister chromatid cohesion (2000) (274)
- Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability (2001) (272)
- A screen for genes required for meiosis and spore formation based on whole-genome expression (2001) (271)
- Cohesin: a catenase with separate entry and exit gates? (2011) (265)
- The sequence of the DNAs coding for the mating-type loci of saccharomyces cerevisiae (1981) (254)
- Human Scc4 Is Required for Cohesin Binding to Chromatin, Sister-Chromatid Cohesion, and Mitotic Progression (2006) (248)
- Eco1 Is a Novel Acetyltransferase that Can Acetylate Proteins Involved in Cohesion (2002) (245)
- Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation (2012) (245)
- Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. (2010) (244)
- Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners. (2003) (241)
- Role of DNA replication in the repression of silent mating type loci in yeast (1984) (241)
- A role for cohesin in T cell receptor rearrangement and thymocyte differentiation (2011) (241)
- Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. (1999) (237)
- Molecular analysis of a cell lineage (1983) (235)
- Closing the cohesin ring: Structure and function of its Smc3-kleisin interface (2014) (234)
- Yeast origin recognition complex is involved in DNA replication and transcriptional silencing (1993) (233)
- Resolution of Chiasmata in Oocytes Requires Separase-Mediated Proteolysis (2006) (228)
- Two Fission Yeast Homologs of Drosophila Mei-S332 Are Required for Chromosome Segregation during Meiosis I and II (2004) (228)
- Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I. (2003) (228)
- The regulation of yeast mating-type chromatin structure by SIR: An action at a distance affecting both transcription and transposition (1982) (224)
- Sister chromatid separation and chromosome re‐duplication are regulated by different mechanisms in response to spindle damage (1999) (223)
- Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle (2004) (221)
- Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I (2003) (220)
- The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry (1990) (216)
- A Topological Interaction between Cohesin Rings and a Circular Minichromosome (2005) (214)
- Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase (1978) (213)
- Molecular genetics of yeast mating type. (1982) (209)
- Structure and function of the PP2A-shugoshin interaction. (2009) (203)
- Regulation of APC/C Activity in Oocytes by a Bub1-Dependent Spindle Assembly Checkpoint (2009) (202)
- Positive feedback in the activation of Gl cyclins in yeast (1991) (201)
- Phosphorylation by Cyclin B-Cdk Underlies Release of Mitotic Exit Activator Cdc14 from the Nucleolus (2004) (199)
- How Do so Few Control so Many? (2005) (195)
- ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex (2011) (195)
- Yeast G1 cyclins CLN1 and CLN2 and a GAP‐like protein have a role in bud formation. (1993) (194)
- Building and breaking bridges between sister chromatids. (2003) (192)
- Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis (2010) (191)
- Monopolar Attachment of Sister Kinetochores at Meiosis I Requires Casein Kinase 1 (2006) (189)
- Maintenance of Cohesin at Centromeres after Meiosis I in Budding Yeast Requires a Kinetochore-Associated Protein Related to MEI-S332 (2004) (187)
- Characterization of two genes required for the position‐effect control of yeast mating‐type genes. (1984) (185)
- Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication (1987) (184)
- A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast (1992) (177)
- MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro (1993) (176)
- Transcriptional regulation in the yeast life cycle. (1987) (175)
- A position effect in the control of transcription at yeast mating type loci (1981) (175)
- Regulation of mating-type information in yeast. Negative control requiring sequences both 5' and 3' to the regulated region. (1984) (175)
- Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin‐ and Dbf4‐dependent kinases (1998) (174)
- Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. (1996) (174)
- Organization of Chromosomal DNA by SMC Complexes. (2019) (173)
- Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei (2010) (171)
- ASH1 mRNA localization in yeast involves multiple secondary structural elementsand Ash1 protein translation (1999) (170)
- Evolution of the cell cycle. (1995) (163)
- An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. (2010) (162)
- In vitro mutation analysis of the mating-type locus in yeast (1981) (162)
- Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast (1987) (156)
- Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression (2006) (153)
- Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF. (2001) (151)
- Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans (2001) (149)
- The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1 (1996) (148)
- Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe (2004) (147)
- The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase. (1997) (138)
- Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation (2018) (137)
- Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-α-associated protein Ctf4 is essential for chromatid disjunction during meiosis II (2004) (137)
- Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast (1985) (137)
- Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19. (2003) (128)
- Separating sister chromatids. (1999) (124)
- TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. (1996) (123)
- A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription. (1991) (121)
- Anatomy of a transcription factor important for the Start of the cell cycle in Saccharomyces cerevisiae (1992) (120)
- Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. (1988) (120)
- Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq (2015) (118)
- Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast (2000) (115)
- Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast (1980) (115)
- Pds5 promotes and protects cohesin acetylation (2013) (112)
- A Prize for Proliferation (2001) (112)
- A repetitive DNA sequence that confers cell-cycle START (CDC28)-dependent transcription of the HO gene in yeast (1985) (109)
- Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5 (2018) (109)
- At least 1400 base pairs of 5′-flanking DNA is required for the correct expression of the HO gene in yeast (1985) (107)
- A REC8-Dependent Plant Shugoshin Is Required for Maintenance of Centromeric Cohesion during Meiosis and Has No Mitotic Functions (2005) (107)
- The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms (2017) (106)
- Model scenarios for evolution of the eukaryotic cell cycle. (1998) (104)
- Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeast (1987) (102)
- Cyclin-dependent Kinase Site-regulated Signal-dependent Nuclear Localization of the SWI5 Yeast Transcription Factor in Mammalian Cells (*) (1995) (101)
- Regulating the HO endonuclease in yeast. (1993) (101)
- How might cohesin hold sister chromatids together? (2005) (101)
- A folded conformation of MukBEF and cohesin (2018) (101)
- Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I (2009) (100)
- Cell cycle-regulated transcription of the CLB2 gene is dependent on Mcm1 and a ternary complex factor (1995) (100)
- Releasing Activity Disengages Cohesin’s Smc3/Scc1 Interface in a Process Blocked by Acetylation (2016) (99)
- The Kinetochore Proteins Pcs1 and Mde4 and Heterochromatin Are Required to Prevent Merotelic Orientation (2007) (99)
- Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells (2020) (99)
- Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation. (2004) (99)
- Temperature-sensitive lethal mutants in the structural gene for dna ligase in the yeast schizosaccharomyces pombe (1977) (98)
- The effect of cell mass on the cell cycle timing and duration of S-phase in fission yeast. (1979) (98)
- Dams and sluices (1993) (97)
- Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis (2013) (96)
- Cohesin's Concatenation of Sister DNAs Maintains Their Intertwining (2011) (95)
- Condensin confers the longitudinal rigidity of chromosomes (2015) (94)
- Spo13 Facilitates Monopolin Recruitment to Kinetochores and Regulates Maintenance of Centromeric Cohesion during Yeast Meiosis (2004) (93)
- Characterization of the DOC1/APC10 Subunit of the Yeast and the Human Anaphase-promoting Complex* (1999) (91)
- Evolution of condensin and cohesin complexes driven by replacement of Kite by Hawk proteins (2017) (89)
- A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae. (1991) (87)
- Novel Genes Required for Meiotic Chromosome Segregation Are Identified by a High-Throughput Knockout Screen in Fission Yeast (2005) (86)
- EGT2 gene transcription is induced predominantly by Swi5 in early G1 (1996) (85)
- Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control. (1995) (85)
- Cohesin's ATPase Activity Is Stimulated by the C-Terminal Winged-Helix Domain of Its Kleisin Subunit (2006) (82)
- Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast. (1991) (82)
- Scc2/Nipbl hops between chromosomal cohesin rings after loading (2017) (80)
- The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6 (1996) (80)
- Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening (2016) (79)
- The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions (2004) (74)
- Zinc-finger motifs expressed in E. coli and folded in vitro direct specific binding to DNA (1988) (71)
- A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion (2010) (70)
- A physical assay for sister chromatid cohesion in vitro. (2007) (69)
- pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe. (1994) (67)
- Isolation of a gene from Drosophila by complementation in yeast (1981) (66)
- Structure and function of cohesin’s Scc3/SA regulatory subunit (2014) (66)
- Dependency of the Spindle Assembly Checkpoint on Cdk1 Renders the Anaphase Transition Irreversible (2014) (65)
- A Direct Role for Cohesin in Gene Regulation and Ecdysone Response in Drosophila Salivary Glands (2010) (64)
- The determination of mother cell‐specific mating type of switching in yeast by a specific regulator of HO transcription (1987) (64)
- SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast. (1993) (63)
- A new method for the isolation of recombinant baculovirus (1992) (62)
- Cdc 53 / cullin and the essential Hrt 1 RING – H 2 subunit of SCF define a ubiquitin ligase module that activates the E 2 enzyme Cdc 34 (1999) (61)
- Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes (2013) (61)
- The cytoskeleton in mRNA localization and cell differentiation. (1997) (60)
- Tandem affinity purification of functional TAP-tagged proteins from human cells (2007) (60)
- High-throughput knockout screen in fission yeast (2006) (59)
- Evolution of Eukaryotic Cell Cycle Regulation Stepwise Addition of Regulatory Kinases and Late Advent of the CDKs (2003) (58)
- Control of Shugoshin Function during Fission-Yeast Meiosis (2005) (58)
- A control acting over the initiation of DNA replication in the yeast Schizosaccharomyces pombe. (1979) (57)
- Finishing the cell cycle. (1999) (56)
- FAR-reaching discoveries about the regulation of START (1990) (53)
- From a single double helix to paired double helices and back. (2004) (53)
- Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex (2019) (52)
- Physical analysis of mating-type loci in Saccharomyces cerevisiae. (1981) (52)
- Cohesin Can Remain Associated with Chromosomes during DNA Replication (2017) (52)
- The cell cycle (2011) (51)
- Construction of conditional analog-sensitive kinase alleles in the fission yeast Schizosaccharomyces pombe (2007) (51)
- The anaphase promoting complex is required for memory function in mice. (2010) (51)
- Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3 (2020) (51)
- Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1 (2016) (47)
- Cohesin cleavage is insufficient for centriole disengagement in Drosophila (2013) (46)
- Getting through anaphase: splitting the sisters and beyond. (2010) (46)
- Sites required for position-effect regulation of mating-type information in yeast. (1983) (45)
- Another role rolls in (1996) (43)
- Spindle Assembly Checkpoint of Oocytes Depends on a Kinetochore Structure Determined by Cohesin in Meiosis I (2013) (41)
- Cyclin A2 is required for sister chromatid segregation, but not separase control, in mouse oocyte meiosis. (2012) (40)
- Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis. (1997) (37)
- Both Interaction Surfaces within Cohesin's Hinge Domain Are Essential for Its Stable Chromosomal Association (2010) (36)
- Analysis of Genome Architecture during SCNT Reveals a Role of Cohesin in Impeding Minor ZGA. (2020) (34)
- Centromere-Independent Accumulation of Cohesin at Ectopic Heterochromatin Sites Induces Chromosome Stretching during Anaphase (2014) (33)
- SW16 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae (1992) (33)
- GermOnline, a cross-species community knowledgebase on germ cell differentiation (2004) (28)
- Long-range interactions at the HO promoter (1997) (28)
- Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 (2019) (27)
- Structure and Stability of Cohesin ’ s Smc 1-Kleisin Interaction (2004) (27)
- Genetic and enzymatic characterization of conditional lethal mutants of the yeast Schizosaccharomyces pombe with a temperature-sensitive DNA ligase. (1979) (22)
- Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs (2020) (22)
- Is the yeast Anaphase Promoting Complex needed to prevent re‐replication during G2 and M phases? (1997) (21)
- Is chromatin remodeling required to build sister-chromatid cohesion? (2004) (20)
- Cell cycle. Dams and sluices. (1993) (20)
- Mating-type control in Saccharomyces cerevisiae: isolation and characterization of mutants defective in repression by a1-alpha 2 (1989) (19)
- Some facts and thoughts on cell cycle control in yeast. (1991) (19)
- Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast (1985) (19)
- Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes (2021) (19)
- Scc 2 Is a Potent Activator of Cohesin ’ s ATPase that Promotes Loading by Binding Scc 1 without Pds 5 Graphical Abstract Highlights (2018) (19)
- Transcription factors important for starting the cell cycle in yeast. (1993) (18)
- Control of S Phase (1996) (17)
- A meiotic mystery: How sister kinetochores avoid being pulled in opposite directions during the first division (2015) (15)
- The role of DNA replication in the repression of the yeast mating-type silent loci. (1984) (15)
- The Role of SW4 and SW16 in the Activity of Gl Cyclins in Yeast (1991) (13)
- Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8 (2020) (12)
- Cohesin disrupts polycomb-dependent chromosome interactions (2019) (12)
- The cohesin ring concatenates sister DNAs (2008) (12)
- How are DNAs woven into chromosomes? (2017) (12)
- Splitting the chromosome: cutting the ties that bind sister chromatids. (2000) (11)
- MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface (2021) (11)
- ParticleStats: open source software for the analysis of particle motility and cytoskeletal polarity (2010) (10)
- A homage to Giardia (1996) (9)
- A U-turn in the regulation of transcription? (1986) (8)
- Multiple interactions between Scc1 and Scc2 activate cohesin’s DNA dependent ATPase and replace Pds5 during loading (2017) (8)
- APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity (2017) (7)
- DNA passes through cohesin’s hinge as well as its Smc3–kleisin interface (2022) (7)
- Eukaryotic gene cloning and expression in yeast (1978) (6)
- Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 but is unnecessary during S phase for establishing cohesion (2019) (6)
- Scc2-mediated loading of cohesin onto chromosomes in G1 yeast cells is insufficient to build cohesion during S phase (2017) (6)
- Retinoblastoma protein. Another role rolls in. (1996) (5)
- High-altitude walking with YACs (1987) (5)
- DNA replication in Schizosaccharomyces pombe (1977) (5)
- Erratum: BAC TransgeneOmics: A high-throughput method for exploration of protein function in mammals (Nature Methods (2008) vol. 5 (409-415)) (2008) (5)
- Sister chromatid cohesion in budding yeast (1996) (5)
- The magic and meaning of Mendel’s miracle (2022) (4)
- unscheduled hepatocyte proliferation Loss of the anaphase-promoting complex in quiescent cells causes Material Supplemental (2004) (4)
- The cell cycle By Andrew M. Murray and Timothy Hunt. New York: Oxford University Press. (1993). 251 pp. $45.00 (1994) (4)
- MCPH 1 inhibits condensin II during interphase by regulating its SMC 2-kleisin 1 interface 2 3 (3)
- Erratum: Genes involved in sister chromatid separation are needed for B- type cyclin proteolysis in budding yeast (Cell (1995) 81 (269-278)) (1998) (3)
- No Evidence that Cse1p Is Required for Cyclin Proteolysis (1998) (3)
- Cell multiplication - Overview (1997) (3)
- The topology of DNA entrapment by cohesin rings (2018) (3)
- Splitting the nucleus: what's wrong with the tripartite ring model? (2010) (2)
- How do cells control the timing of DNA replication and mitosis? (1992) (2)
- Cell multiplication. (1997) (2)
- Structure and Function of Cohesins Scc3/Sa Regulatory Subunit (2014) (2)
- Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF. (2016) (2)
- Asymmetric localization of Ash1 mRNA in S-cerevisiae as determined by fluorescent in situ hybridization. (1996) (1)
- Splitting sister chromatids. (2003) (1)
- Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding (2022) (1)
- ASYMMETRIC ACCUMULATION OF ASH1 IN POST ANAPHASE NUCLEI DEPENDS ON A MYOSIN AND RESTRICTS YEAST MATING TYPE SWITCHING TO MOTHER CELLS (1996) (1)
- Author response: Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes (2013) (1)
- ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring (2020) (1)
- Eukaryotic expression vectors. (1985) (1)
- How does cohesin hold sister DNAs together (2009) (1)
- Author response: Transport of DNA within cohesin involves clamping on top of engaged heads by Scc2 and entrapment within the ring by Scc3 (2020) (1)
- The IMP and European Molecular Biology: Moving the Centre Eastwards (1999) (1)
- The structure and function of SMC-kleisin complexes (2009) (1)
- Explorer The kinetochore proteins Pcs 1 and Mde 4 and heterochromatin are required to prevent merotelic orientation (2017) (1)
- BIME joins the destruction team. (1997) (1)
- A Unified Nomenclature for Protein Subunits of Mediator Complexes Conserved from Fungi to Humans: Med6/pmc5/arc/ Drip33/trap32, Med7/arc/drip/trap34/crsp33, Linking Transcriptional Regulators to Rna Polymerase Ii Arc/crsp/drip150/trap170, Soh1/trap18 (note That Soh1 Has Not Been yet Identified in Pu (0)
- New players in separating sister chromatids during mitosis. Potential new drug targets (1999) (0)
- SMC hinge domain from T. maritima with coiled coil (2002) (0)
- Exciting future planned for birthplace of genetics (2001) (0)
- Author response: Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs (2020) (0)
- New Recombinant virus, their use and their production (1991) (0)
- new for the isolation of reconn (0)
- The magic and meaning of Mendel’s miracle (2022) (0)
- SMC hinge domain from T. maritima w/o coiled coil, P212121 crystal form (2002) (0)
- A process for the preparation of the Anaphase Promoting Complex (1997) (0)
- How do cells establish and maintain sister chromatid cohesion (2012) (0)
- Designing a new cross-linkable cohesin complex for studying cohesin`s interaction with DNA (2012) (0)
- Isolation of genes by complementati of a cell-cycle gene (Saccharomyces cerevisiae/ cdc28/ recombinant plasmid/transforn (2016) (0)
- Chromosome segregation one hundred and one years after Mendel's rediscovery. (2001) (0)
- The mechanism by which chromosomal DNA molecules are held together: entrapment within cohesin rings? (2015) (0)
- Folded elbow of cohesin (2021) (0)
- Author response: Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 (2019) (0)
- SMC hinge heterodimer (Mouse) (2010) (0)
- Changing places (2004) (0)
- Regulating the duplication and segregation of chromosomes in yeast (1997) (0)
- Introduction: dissection and simplification of chromosome segregation (2005) (0)
- Sc Smc1hd:Scc1-C complex, ATPgS (2004) (0)
- Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex (2020) (0)
- Abstracts of the First Biennial Symposium on Regulatory T Cells and T Helper Cells. March 30, 2012. London, United Kingdom. (2012) (0)
- Anatomy of a leech (1996) (0)
- Erratum: Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in moeisosi I (Developmental Cell (2003) vol. 4 (535-548)) (2003) (0)
- Document S1. Table S1 (2012) (0)
- Sister chromatid cohesion establishment during DNA replication termination (2022) (0)
- Scc2 and Scc3 promote distinct modes of topological association between cohesin and DNA (2020) (0)
- Formation of the clamped state by Scc2 and DNA overcomes the constraints imposed by zipping-up of the SMC coiled coils on cohesin’s ATPase (2022) (0)
- Cohesin subunit Scc3 from Z. rouxii, 88-1035 (2014) (0)
- Crystal structure of the DNA-binding domain of MBP1, a transcription factor important in progression from G1 to S phase (1996) (0)
- Cohesin subunit Pds5 in complex with Scc1 (2016) (0)
- 11 Control of S Phase (1996) (0)
- Cell multiplication. (1995) (0)
- cohesin Smc3-HD:Scc1-N complex from yeast (2014) (0)
- What AlphaFold tells us about cohesin’s retention on and release from chromosomes (2023) (0)
- Activating the HO promoter. (2001) (0)
- Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences: 354 (1389) (1999) (0)
- A folded conformation of MukBEF and cohesin (2019) (0)
- Supplemental Information Crystal Structure of the Cohesin Gatekeeper Pds 5 and in Complex with Kleisin Scc (2016) (0)
- How Far Will We See in the Future? (2010) (0)
- Pericentric heterochromatin gets sticky when misplaced at chromosome arms (2013) (0)
- A Eukaryotic Cell Cycle (1997) (0)
- Activation of S-~ hase-~ romoting : CDKs in late G , definis a " pbint of noUreturn 1 ' after whkh Cdc 6 svithesis cannot promote DNA replication in yeast (2007) (0)
- DNA-BINDING DOMAIN OF MBP1 (1999) (0)
- Cell cycle research proliferates. The Research Institute of Molecular Pathology (I.M.P.). Fourth International Conference on the Control of Proliferation in Normal and Malignant Cells, Vienna, Austria, May 3-5, 1991. (1991) (0)
- Cohesin subunit Pds5 (2016) (0)
- Closing the cohesin ring by structural biology (2016) (0)
- REGULATING THE CDC28 PROTEIN-KINASE IN THE BUDDING YEAST SACCHAROMYCES-CEREVISIAE - FROM START TO FINISH (1994) (0)
- SWITCHING GENES ON AT THE START OF THE YEAST-CELL CYCLE (1993) (0)
- Abstract PR11: APC/CCdh1 maintains primordial follicles, germinal vesicle arrest and ensures balanced segregation of chromosomes by enabling removal of Shugoshin-2 from chromosomes arms (2016) (0)
- Chromosome segregation one hundred years after Mendel's rediscovery (2001) (0)
- Crystal Structure of the C ohesin Gatekeeper Pds 5 and in Complex with Kleisin Scc 1 Graphical Abstract Highlights (2016) (0)
- Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation (2018) (0)
- Investigations into the regulation of sister chromatid cohesion (2014) (0)
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