Kim Sung-hoon
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Most Influential Person Now
South Korean scientist
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Physics
Kim Sung-hoon 's Degrees
- Bachelors Physics Seoul National University
Why Is Kim Sung-hoon Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Kim Sunghoon is a South Korean biologist. Education 1981 B.S. Seoul National University1983 M.S. Korea Advanced Institute of Science and Technology1991 Ph.D. Brown University, U.S. Work Dr. Sunghoon Kim has been studying novel functions of human aminoacyl-tRNA synthetases and searching for their pathophysiological connections to human diseases. He has identified potent novel tumor suppressors such as AIMP2/p38, AIMP3/p18. Besides, he has also investigated novel extracellular activities of ARSs and associated factors such as lysyl-tRNA synthetase, tryptophanyl-tRNA synthetase and AIMP1/p43. He also discovered the oncogenic variant of AIMP2, designated AIMP2-DX2, as one of the critical factors that determines the survival of lung cancer patients. More recently, he found that leucyl-tRNA synthetase serves as an amino acid sensor for mTOR signal pathway.
Kim Sung-hoon 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway (2012) (695)
- PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase (2020) (674)
- The BioMart community portal: an innovative alternative to large, centralized data repositories (2015) (642)
- Aminoacyl tRNA synthetases and their connections to disease (2008) (329)
- Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers. (2005) (255)
- Noncanonical Function of Glutamyl-Prolyl-tRNA Synthetase Gene-Specific Silencing of Translation (2004) (237)
- Aminoacyl-tRNA synthetase complexes: beyond translation (2004) (231)
- Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ. (2013) (190)
- Heat Shock Protein Hsp72 Is a Negative Regulator of Apoptosis Signal-Regulating Kinase 1 (2002) (174)
- Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation (2003) (168)
- Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping (2011) (166)
- Agonist Recognition Sites in the Cytosolic Tails of Vanilloid Receptor 1* (2002) (166)
- LysRS serves as a key signaling molecule in the immune response by regulating gene expression. (2009) (147)
- Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. (2005) (142)
- A Cofactor of tRNA Synthetase, p43, Is Secreted to Up-regulate Proinflammatory Genes* (2001) (135)
- The Haploinsufficient Tumor Suppressor p18 Upregulates p53 via Interactions with ATM/ATR (2005) (134)
- Apoptosis Signal-regulating Kinase 1 Controls the Proapoptotic Function of Death-associated Protein (Daxx) in the Cytoplasm* (2001) (123)
- Structural switch of lysyl-tRNA synthetase between translation and transcription. (2013) (121)
- Aminoacyl-tRNA synthetases as therapeutic targets (2019) (119)
- Nucleolar Localization of Human Methionyl–Trna Synthetase and Its Role in Ribosomal RNA Synthesis (2000) (117)
- Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis (2012) (117)
- p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: Implications for its physiological significance (2002) (115)
- AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53 (2008) (109)
- Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (2011) (105)
- Dose-dependent Biphasic Activity of tRNA Synthetase-associating Factor, p43, in Angiogenesis* (2002) (104)
- The novel cytokine p43 stimulates dermal fibroblast proliferation and wound repair. (2005) (103)
- Tumor Suppressor miRNA-204-5p Regulates Growth, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer. (2019) (102)
- Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping (2011) (99)
- Cellular Distribution of Lysyl-tRNA Synthetase and Its Interaction with Gag during Human Immunodeficiency Virus Type 1 Assembly (2004) (91)
- Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis (2011) (86)
- Precursor of Pro-apoptotic Cytokine Modulates Aminoacylation Activity of tRNA Synthetase* (1999) (84)
- Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress (2014) (81)
- Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling. (2012) (79)
- Retrovirus-Specific Packaging of Aminoacyl-tRNA Synthetases with Cognate Primer tRNAs (2002) (79)
- Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug (2012) (76)
- AIMP2 promotes TNFα-dependent apoptosis via ubiquitin-mediated degradation of TRAF2 (2009) (76)
- Hierarchical Network between the Components of the Multi-tRNA Synthetase Complex (2006) (76)
- Aminoacyl‐tRNA synthetase–interacting multifunctional proteins (AIMPs): A triad for cellular homeostasis (2010) (74)
- Interaction of two translational components, lysyl‐tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin‐dependent cell migration (2012) (74)
- Mapping of a higher order protein-DNA complex: Two kinds of long-range interactions in λ attL (1990) (73)
- Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling. (2016) (72)
- Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation. (2002) (66)
- A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase (2004) (66)
- Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers (2016) (65)
- Signaling pathways for TNF production induced by human aminoacyl-tRNA synthetase-associating factor, p43. (2002) (65)
- CDA: Combinatorial Drug Discovery Using Transcriptional Response Modules (2012) (64)
- Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells (2017) (62)
- Pediatric solid malignancies: neuroblastoma and Wilms' tumor. (2006) (62)
- Molecular network and functional implications of macromolecular tRNA synthetase complex. (2003) (62)
- MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer (2014) (61)
- Hormonal activity of AIMP1/p43 for glucose homeostasis (2006) (61)
- Use of acetylated softwood kraft lignin as filler in synthetic polymers (2012) (61)
- Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains* (2015) (58)
- Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction (2017) (57)
- AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability. (2006) (57)
- Monocyte cell adhesion induced by a human aminoacyl‐tRNA synthetase‐associated factor, p43: identification of the related adhesion molecules and signal pathways (2002) (57)
- Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase (2015) (57)
- A Multifunctional Repeated Motif Is Present in Human Bifunctional tRNA Synthetase* (1998) (56)
- Discovery of novel indazole-linked triazoles as antifungal agents. (2007) (54)
- Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway (2018) (53)
- A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells (2014) (52)
- Splicing variant of AIMP2 as an effective target against chemoresistant ovarian cancer. (2012) (52)
- Separation of extracellular nanovesicles and apoptotic bodies from cancer cell culture broth using tunable microfluidic systems (2017) (52)
- Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection (2016) (52)
- Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex. (2002) (50)
- Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases. (2007) (50)
- miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18 (2014) (49)
- Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction. (2014) (49)
- Protein immobilization on plasma-polymerized ethylenediamine-coated glass slides. (2003) (48)
- Intraoperative cryoanalgesia for managing pain after the Nuss procedure. (2017) (48)
- Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity (2016) (47)
- Determination of Three-dimensional Structure and Residues of the Novel Tumor Suppressor AIMP3/p18 Required for the Interaction with ATM* (2008) (47)
- Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1 (2019) (45)
- Preparation and characterization of thermoplastic polyurethanes using partially acetylated kraft lignin (2013) (45)
- Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice (2010) (44)
- Structure of the ArgRS–GlnRS–AIMP1 complex and its implications for mammalian translation (2014) (44)
- Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer (2015) (43)
- NeuroWander: a BCI game in the form of interactive fairy tale (2010) (42)
- A threonyl-tRNA synthetase-mediated translation initiation machinery (2019) (41)
- MSC p43 required for axonal development in motor neurons (2009) (41)
- Evolution of the multi-tRNA synthetase complex and its role in cancer (2019) (40)
- Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice (2010) (39)
- Screening of quinoline, 1,3-benzoxazine, and 1,3-oxazine-based small molecules against isolated methionyl-tRNA synthetase and A549 and HCT116 cancer cells including an in silico binding mode analysis. (2015) (36)
- Catalytic Peptide of Human Glutaminyl-tRNA Synthetase Is Essential for Its Assembly to the Aminoacyl-tRNA Synthetase Complex* (2000) (36)
- Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases (2018) (35)
- Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis. (2009) (35)
- The Lysosomal Potassium Channel TMEM175 Adopts a Novel Tetrameric Architecture (2017) (35)
- AIMP3/p18 controls translational initiation by mediating the delivery of charged initiator tRNA to initiation complex. (2012) (34)
- Novel regulatory interactions and activities of mammalian tRNA synthetases (2002) (34)
- Inactivation of Organellar Glutamyl- and Seryl-tRNA Synthetases Leads to Developmental Arrest of Chloroplasts and Mitochondria in Higher Plants* (2005) (34)
- Direct Gallbladder Indocyanine Green Injection Fluorescence Cholangiography During Laparoscopic Cholecystectomy. (2017) (34)
- Association of aminoacyl-tRNA synthetases with cancer. (2014) (34)
- Use of transthoracic cryoanalgesia during the Nuss procedure. (2016) (32)
- Structural separation of different extracellular activities in aminoacyl-tRNA synthetase-interacting multi-functional protein, p43/AIMP1. (2006) (31)
- Cancer Association Study of Aminoacyl-tRNA Synthetase Signaling Network in Glioblastoma (2012) (31)
- Heat Shock Protein 90 Mediates Protein-protein Interactions between Human Aminoacyl-tRNA Synthetases* (2000) (31)
- Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents. (2004) (31)
- Released Tryptophanyl-tRNA Synthetase Stimulates Innate Immune Responses against Viral Infection (2018) (29)
- Preparation and Characterization of Superabsorbent Polymers Based on Starch Aldehydes and Carboxymethyl Cellulose (2018) (29)
- Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification (2017) (29)
- Chapter 1: The physiological role of lysyl tRNA synthetase in the immune system. (2009) (28)
- Determination of Structural Models of the Complex between the Cytoplasmic Domain of Erythrocyte Band 3 and Ankyrin-R Repeats 13–24* (2011) (28)
- Lysyl-tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis (2018) (28)
- Protein-protein interactions and multi-component complexes of aminoacyl-tRNA synthetases. (2014) (28)
- Antitumor activity of the novel human cytokine AIMP1 in an in vivo tumor model. (2006) (27)
- Antitumor activity and pharmacokinetic properties of ARS-interacting multi-functional protein 1 (AIMP1/p43). (2010) (26)
- The incidence of neuropathic pain after intercostal cryoablation during the Nuss procedure (2019) (26)
- Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development (2019) (26)
- A theoretical model for p53 dynamics: Identifying optimal therapeutic strategy for its activation and stabilization (2009) (25)
- Identification of CD23 as a functional receptor for the proinflammatory cytokine AIMP1/p43 (2012) (25)
- AIMP2 Controls Intestinal Stem Cell Compartments and Tumorigenesis by Modulating Wnt/β-Catenin Signaling. (2016) (24)
- O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis (2016) (24)
- Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2. (2016) (24)
- Extracellular activities of aminoacyl-tRNA synthetases: new mediators for cell-cell communication. (2014) (23)
- Smooth solution for the porous medium equation in a bounded domain (2009) (23)
- HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy (2019) (23)
- Novel Morphologic and Genetic Analysis of Cancer Cells in a 3D Microenvironment Identifies STAT3 as a Regulator of Tumor Permeability Barrier Function. (2016) (23)
- Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations (2019) (23)
- Design and synthesis of quinolinones as methionyl-tRNA synthetase inhibitors. (2006) (22)
- 2-[2-Substituted-3-(3,4-dichlorobenzylamino)propylamino]-1H-quinolin-4-ones as Staphylococcus aureus methionyl-tRNA synthetase inhibitors. (2009) (22)
- Tpl2 Kinase Impacts Tumor Growth and Metastasis of Clear Cell Renal Cell Carcinoma (2013) (22)
- AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity (2018) (21)
- Minimally invasive thoracoscopic repair of unilateral pectus carinatum. (2009) (21)
- Pharmacophore-based virtual screening: the discovery of novel methionyl-tRNA synthetase inhibitors. (2006) (21)
- AIMP1/p43 downregulates TGF-beta signaling via stabilization of smurf2. (2008) (21)
- ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation (2019) (20)
- Ciliated hepatic foregut cyst in a young child. (2005) (20)
- In vitro development of resistance to a novel fluoroquinolone, DW286, in methicillin-resistant Staphylococcus aureus clinical isolates. (2003) (20)
- Simultaneous detection of bioavailable arsenic and cadmium in contaminated soils using dual-sensing bioreporters (2016) (20)
- Aminoacyl-tRNA Synthetases and amino acid signaling. (2020) (20)
- Stabilization of Cyclin-Dependent Kinase 4 by Methionyl-tRNA Synthetase in p16INK4a-Negative Cancer. (2018) (20)
- Laparoscopically assisted antegrade percutaneous endoscopic gastrostomy. (2010) (19)
- Compressive viscoelastic properties of softwood kraft lignin-based flexible polyurethane foams (2013) (19)
- Glutamyl‐prolyl‐tRNA synthetase induces fibrotic extracellular matrix via both transcriptional and translational mechanisms (2018) (19)
- Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases. (2005) (19)
- Chemical suppression of an oncogenic splicing variant of AIMP2 induces tumour regression. (2013) (19)
- Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration (2018) (18)
- Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. (2016) (18)
- PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine (2015) (18)
- Lentiviral vector-mediated shRNA against AIMP2-DX2 suppresses lung cancer cell growth through blocking glucose uptake (2012) (18)
- Degradation of AIMP1/p43 Induced by Hepatitis C Virus E2 Leads to Upregulation of TGF-β Signaling and Increase in Surface Expression of gp96 (2014) (18)
- Toll-like receptor 4-mediated c-Jun N-terminal kinase activation induces gp96 cell surface expression via AIMP1 phosphorylation. (2010) (18)
- Anterior chest wall elevation using a T-fastener suture technique during a Nuss procedure. (2014) (17)
- Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation (2018) (17)
- Importin Beta Plays an Essential Role in the Regulation of the LysRS-Ap4A Pathway in Immunologically Activated Mast Cells (2011) (17)
- Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex (2013) (17)
- Multifunctional Proteins in Tumorigenesis: Aminoacyl-tRNA Synthetases and Translational Components (2006) (17)
- Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase (2019) (16)
- Aminoacyl-tRNA synthetase-interacting multi-functional protein 1/p43: an emerging therapeutic protein working at systems level (2008) (16)
- Endoscopic treatment of Morel-Lavallee lesion. (2016) (16)
- Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase. (2019) (16)
- Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration. (2019) (16)
- A novel in vitro permeability assay using three-dimensional cell culture system. (2015) (16)
- A novel adenoviral vector-mediated mouse model of Charcot-Marie-Tooth type 2D (CMT2D) (2014) (15)
- Ratio of Autoantibodies of Tumor Suppressor AIMP2 and Its Oncogenic Variant Is Associated with Clinical Outcome in Lung Cancer (2017) (15)
- Structure of the N-terminal extension of human aspartyl-tRNA synthetase: implications for its biological function. (2003) (14)
- Nuclear localization of aminoacyl-tRNA synthetases using single-cell capillary electrophoresis laser-induced fluorescence analysis. (2004) (14)
- Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors. (2016) (14)
- Discovery of (S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase (LRS)-targeted mTORC1 inhibitor. (2016) (14)
- Expression of stress‐induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer (2014) (14)
- Autoantibodies against aminoacyl-tRNA synthetase: novel diagnostic marker for type 1 diabetes mellitus (2010) (14)
- Tpl2 induces castration resistant prostate cancer progression and metastasis (2015) (14)
- Effect of alkyl-chain-modified lignin in the PLA matrix (2014) (14)
- Protein Adsorption on the Nickel-coated Glass Slide for Protein Chips (2002) (13)
- Radiological risk factors for progression of ossification of posterior longitudinal ligament following laminoplasty. (2017) (13)
- Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage (2019) (13)
- Leucine-induced localization of Leucyl-tRNA synthetase in lysosome membrane. (2017) (13)
- Experimental study on shear connection in unfilled composite steel grid bridge deck (2010) (13)
- Multiple reaction monitoring of multiple low-abundance transcription factors in whole lung cancer cell lysates. (2013) (12)
- Do Aminoacyl‐tRNA synthetases have biological functions other than in protein biosynthesis? (2006) (12)
- GARNET – gene set analysis with exploration of annotation relations (2011) (12)
- Characterization of the interaction between lysyl‐tRNA synthetase and laminin receptor by NMR (2014) (12)
- Entamoeba lysyl-tRNA Synthetase Contains a Cytokine-Like Domain with Chemokine Activity towards Human Endothelial Cells (2011) (12)
- Identification of a New Morpholine Scaffold as a P2Y12 Receptor Antagonist (2016) (12)
- Aminoacyl-tRNA Synthetases in Biology and Medicine (2014) (11)
- Aminoacyl‐tRNA synthetase‐interacting multi‐functional protein, p43, is imported to endothelial cells via lipid rafts (2005) (11)
- CLC anion channel regulatory phosphorylation and conserved signal transduction domains. (2012) (11)
- Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion (2020) (11)
- Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels (2015) (11)
- Function of membranous lysyl-tRNA synthetase and its implication for tumorigenesis. (2016) (11)
- Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cell‑extracellular matrix adhesion for migration. (2016) (11)
- Identification of upstream regulators for prognostic expression signature genes in colorectal cancer (2013) (11)
- Biochemical and phylogenetic analyses of methionyl‐tRNA synthetase isolated from a pathogenic microorganism, Mycobacterium tuberculosis (1998) (10)
- AIMP1 deficiency enhances airway hyperreactivity in mice via increased TH2 immune responses. (2012) (10)
- Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3. (2021) (10)
- Facile one-step synthesis of tetrachalcogenotetrairon(2+) (chalcogen = sulfur, selenium) cubane-like centers (1988) (10)
- Synthesis and Structure-Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy. (2020) (10)
- Structural Arrangement of the Intracellular Ca2+ Binding Domains of the Cardiac Na+/Ca2+ Exchanger (NCX1.1) (2012) (9)
- Chemical modulators working at pharmacological interface of target proteins. (2012) (9)
- Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis (2018) (9)
- Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. (2018) (9)
- Bayesian neural network with pretrained protein embedding enhances prediction accuracy of drug-protein interaction (2020) (9)
- A new staining method using methionyl-tRNA synthetase 1 antibody for brushing cytology of bile duct cancer. (2019) (9)
- The DRS–AIMP2–EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex (2019) (8)
- Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer (2019) (8)
- Potential of a bio-disintegrable polymer blend using alkyl-chain-modified lignin (2015) (8)
- Repair of Earthquake Damaged RC Columns with Stainless Steel Wire Mesh Composite (2010) (8)
- GCIceNet: a graph convolutional network for accurate classification of water phases. (2020) (8)
- Interaction of the C-terminal Domain of p43 and the α Subunit of ATP Synthase (2002) (8)
- Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity. (2018) (8)
- Identification of master regulator candidates in conjunction with network screening and inference (2013) (8)
- Synthesis of Substituted Imidazolidin-2-ones as Aminoacyl-tRNA Synthase Inhibitors † (2010) (8)
- Changes of Lignin Molecular Structures in a Modification of Kraft Lignin Using Acid Catalyst (2016) (7)
- Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. (2017) (7)
- Mechanics of a stuck central venous catheter removal. (2016) (7)
- Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2 (2020) (7)
- Promiscuous Methionyl-tRNA Synthetase Mediates Adaptive Mistranslation against Oxidative Stresses (2014) (6)
- Liposomal borrelidin for treatment of metastatic breast cancer (2018) (6)
- 2-Aminophenylpyrimidines as Novel Inhibitors of Aminoacyl-tRNA Synthetase Interacting Multifunctional Protein 2 (AIMP2)-DX2 for Lung Cancer Treatment. (2020) (6)
- Vertex corrections to the dc conductivity in anisotropic multiband systems (2019) (6)
- Solvatokinetic and Solvatochromic Behavior of Bis(indolinobenzospiropyranyl) Sulfide Derivatives in Various Solvents (2004) (6)
- Enhancement of Toll‐like receptor 2‐mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells (2011) (6)
- Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis. (2021) (6)
- Intrauterine gastric perforation (2006) (6)
- Laparoscopically assisted repair of inguinal hernia through a micro-incision and extra-peritoneal division and ligation of the hernia sac (2013) (6)
- Minimizing unnecessary parenteral nutrition after appendectomy in children. (2013) (6)
- Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1). (2019) (6)
- Characterization of an Escherichia coli mutant, feeA, displaying resistance to the calmodulin inhibitor 48/80 and reduced expression of the rare tRNA3Leu (1996) (6)
- Minimally invasive repair of symmetric pectus carinatum: bilateral thoracoscopic chondrotomies and suprasternal compression bar placement. (2012) (5)
- How Does Screw Migration or Fracture After Anterior Cervical Plate Fixation Affect the Radiographic and Clinical Outcomes? (2019) (5)
- Comprehensive data resources and analytical tools for pathological association of aminoacyl tRNA synthetases with cancer (2015) (5)
- Approximate Analysis of Simply Supported Composite Beams with Partial Interaction (2011) (5)
- Automated Structure Refinement for a Protein Heterodimer Complex Using Limited EPR Spectroscopic Data and a Rigid-Body Docking Algorithm: A Three-Dimensional Model for an Ankyrin-CDB3 Complex (2014) (5)
- AIMP1 negatively regulates adipogenesis by inhibiting PPAR&ggr; (2014) (5)
- Publisher Correction: Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations (2019) (5)
- Biocon's target factory (2018) (5)
- Mapping the contact surfaces in the Lamin A:AIMP3 complex by hydrogen/deuterium exchange FT-ICR mass spectrometry (2017) (5)
- TID-Tolerant Inverter Designs for Radiation-Hardened Digital Systems (2020) (5)
- Use of intraoperative lateral pelvic X-ray to localize and ensure coccyx removal during sacrococcygeal teratoma resection (2017) (5)
- Exosomal secretion of truncated cytosolic lysyl-tRNA synthetase induces inflammation during cell starvation (2018) (4)
- Fragment-based methods for the discovery of inhibitors modulating lysyl-tRNA synthetase and laminin receptor interaction. (2017) (4)
- High-Throughput Screening for Protein Synthesis Inhibitors Targeting Aminoacyl-tRNA Synthetases (2018) (4)
- Hepatic vascular malformation in a patient with Simpson–Golabi–Behmel syndrome (2007) (4)
- Vascular clamp stabilization of pylorus during laparoscopic pyloromyotomy (2007) (4)
- Use of pulse oximeter placed on a gastroschisis silo to monitor intestinal oxygen saturation (2006) (4)
- Triglyceride Up-regulates Expression of ABCG1 in PMA-induced THP-1 Macrophages Through Activation of JNK and p38 MAPK Pathways (2014) (4)
- Selecting SNPs for pharmacogenomic association study (2010) (4)
- A procedure for identifying master regulators in conjunction with network screening and inference (2010) (4)
- Abstract 24036: Inhibition Of Prolyl-tRNA Synthetase As A Novel Mediator Of Cardiac Fibrosis (2017) (4)
- Purification and biophysical characterization of the AIMP2-DX2 protein. (2017) (4)
- Assessing bioavailability and genotoxicity of heavy metals and metallic nanoparticles simultaneously using dual-sensing Escherichia coli whole-cell bioreporters (2016) (4)
- Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer (2020) (4)
- O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine (2022) (3)
- Erratum: Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels (2016) (3)
- Effect of Low-Temperature Pyrolysis on the Properties of Jute Fiber-Reinforced Acetylated Softwood Kraft Lignin-Based Thermoplastic Polyurethane (2018) (3)
- A novel sol-gel method to produce the poly-L-lysine coated plate as a platform for protein chips (2003) (3)
- Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma. (2017) (3)
- Modification of U-Stitch Laparoscopic Gastrostomy Technique to Minimize Suture Knot Abscess Formation (2015) (3)
- Images in clinical medicine. Pulmonary sequestration. (2013) (3)
- Cell‐based analysis of pairwise interactions between the components of the multi‐tRNA synthetase complex (2020) (3)
- Structural Arrangement of the Intracellular Ca 2 Binding Domains of the Cardiac Na / Ca 2 Exchanger ( NCX 1 . 1 ) EFFECTS (2013) (3)
- O-GlcNAcylation of Mef2c regulates myoblast differentiation. (2020) (3)
- Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma (2017) (3)
- Minimally invasive repair of asymmetric Pectus Excavatum: An alternative technique to treating asymmetric morphology. (2022) (2)
- Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes (2021) (2)
- Measurement of sternal curvature angle on patients with pectus excavatum (2016) (2)
- Structures and functions of multi-tRNA synthetase complexes. (2020) (2)
- Two distinct receptor-binding domains of human glycyl-tRNA synthetase 1 displayed on extracellular vesicles activate M1 polarization and phagocytic bridging of macrophages to cancer cells. (2022) (2)
- Abstract A58: Galbanic acid isolated from Ferula assafoetida exerts in vivo antitumor activity in association with antiangiogenesis and antiproliferation (2012) (2)
- Gas insufflation of stomach and laparoscope intubation of distal esophagus for measurement of gap in esophageal atresia without distal fistula (2013) (2)
- Diagnosis and treatment of the intra-abdominal gonad in the pediatric population: Testes, ovaries, dysgenetic gonads, streaks, and ovotestes. (2020) (2)
- Allosteric Inhibition of the Tumor-Promoting Interaction between AIMP2-DX2 and HSP70. (2021) (2)
- A Case of Pancreaticobiliary Duct Obstruction due to Pancreatic Tuberculosis Combined with a Colon Adenocarcinoma and Tuberculous Colitis (2007) (2)
- Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction. (2021) (2)
- A method to accurately estimate the catheter length needed for a tunneled central catheter placement (2018) (2)
- DEVELOPMENT OF A NOVEL DRUG-COATED STENT USING CURCUMIN AS ANTIPROLIFERATIVE DRUG (2004) (2)
- Laparoscopic Treatment of Slipping Rib Syndrome in Pediatric Patients. (2020) (2)
- Use of cryoanalgesia as a postoperative pain management for open pectus carinatum repair (2020) (2)
- An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody (2020) (1)
- Genetic Disruption fo p38/JTV1 in Mice Unveiled Its Pleiotropic Activity as A Novel Tumor Suppressor (2003) (1)
- Adenoviral-mediated mouse model of motor impairment in distal spinal muscular atrophy type V (2014) (1)
- Importin Beta Plays an Essential Role in the Regulation of the LysRS-Ap 4 A Pathway in Immunologically Activated Mast Cells (cid:1) (2011) (1)
- Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli (2017) (1)
- Laparoscopic Magnet-Assisted Percutaneous Endoscopic Gastrostomy Placement. (2019) (1)
- From Microcytosis to Macrodiagnosis (2021) (1)
- Role of tRNAs in Breast Cancer Regulation. (2021) (1)
- Determination of structural models of the complex between erythrocyte band 3 and ankyrin-R repeats 13-24 (2011) (1)
- Oncogenic Mutation of AIMP 2 / p 38 Inhibits Its Tumor-Suppressive Interaction with Smurf 2 (2016) (1)
- The effect of adolescents’ subjective self-awareness and sleep states on suicidal ideation (2019) (1)
- Further Research on the Efficacy of a New Navigable Percutaneous Disc Decompression Device (L'DISQ) in Patients with Lumbar Radicular Pain: 2-Year Follow-Up (2016) (1)
- Tunable quantum interference effect on magnetoconductivity in few-layer black phosphorus (2019) (0)
- ISP-18-4 Expression of stress-induced phosphoprotein-1 (STIP-1) was associated with tumor progression and poor prognosis in epithelial ovarian cancer(Group 18 Oncology 9,IS Poster,International Session) (2013) (0)
- Abstract 84: A discovery on splicing variant patterns of leucine-tRNA synthetase gene based on targeted RNA sequencing (2016) (0)
- Structure and Dynamics of the Calcium Binding Domains of the Na/Ca Exchanger (NCX1.1) Determined by Site Directed Spin Labeling (2010) (0)
- Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction (2017) (0)
- Universal Theory of Dynamic Force Microscopy for Exact and Robust Force Reconstruction Using Multiharmonic Signal Analysis. (2021) (0)
- A threonyl-tRNA synthetase-mediated translation initiation machinery (2019) (0)
- Structure of the DNA double helix. Preface. (2014) (0)
- Exon Skipping of AIMP2 and Lymphomagenesis (2018) (0)
- Diffusion-Based Separation of Extracellular Vesicles by Nanoporous Membrane Chip (2021) (0)
- Interaction between human tRNA synthetases involves repeated sequence elements (2005) (0)
- 1H, 13C and 15N resonance assignment of WHEP domains of human glutamyl-prolyl tRNA synthetase (2015) (0)
- AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice (2018) (0)
- Correction: Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma (2018) (0)
- Hormonal activity of AIMP1p43 for glucose homeostasis (2006) (0)
- Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses. (2022) (0)
- In vitro selection of macrocyclic peptides against human aminoacyl-tRNA synthetase complex-interacting protein -1 (AIMP-1) (2013) (0)
- 1H, 13C and 15N resonance assignment of WHEP domains of human glutamyl-prolyl tRNA synthetase (2013) (0)
- Glycoprotein 96 polymorphisms are associated with the risk of systemic lupus erythematosus: A case‐control study (2019) (0)
- Dermal securement of port catheters in obese patients. (2019) (0)
- Investigation of the optimal combination of external beam radiotherapy and high-dose-rate intracavitary brachytherapy in definitive radiotherapy for uterine cervical cancer patients (2008) (0)
- Characteristics of Sympathetic Response in the Patients with Chronic Low Back Pain : A Comparative Study (2011) (0)
- Images in clinical medicine. Peutz-Jeghers syndrome. (2007) (0)
- [Poster] Pancreatosplenectomy in left-sided pancreatic cancer (2011) (0)
- O-GlcNAcylation of orphan nuclear receptor ERRγ promotes hepatic gluconeogenesis (2016) (0)
- Site-Directed Spin-Labeling Studies: Structure of the AnkD34-Cdb3 Complex (2011) (0)
- Laparoscopoic Distal Pancreatosplenectomy in Recurred Gastric Cancer Following Spleen-preserving Radical Total Gastrectomy - Video (2011) (0)
- Postoperative Pancreatic Fistula and Functional Assessment following Transgastric Pancreaticogastrostomy in Managing Remnant Soft Pancreas (2010) (0)
- Magnetic resonance imaging study of orthotic balloon brace used for the treatment of pectus carinatum (2018) (0)
- Mechanism on the Formation of Bis-9,9'-thioxanthenylmethane from the Reaction of Thioxanthylium Ion With Dimethylmercury(I) (1982) (0)
- Enhancing the copper-sensing capability of Escherichia coli-based whole-cell bioreporters by genetic engineering (2017) (0)
- A Case of the Endoscopic Removal of a Duodenal Heterotopic Gastric Mucosa Presenting as a Polypoid Lesion (2007) (0)
- Simultaneous detection of bioavailable arsenic and cadmium in contaminated soils using dual-sensing bioreporters (2016) (0)
- A Case of a Bleeding Dieulafoy's Lesion in a Duodenal Diverticulum Treated by Endoscopic Hemoclipping (2007) (0)
- AIMP1 negatively regulates PPARgamma: Implication in adipogenesis (2014) (0)
- Prognostic Value of Follow-up FDG PET/CT in Stomach Cancer: 2498 (2015) (0)
- Abstract 3001: Aberrantly up-regulated synaptotagmin-like 2 (SYTL2) promotes tumorigenesis of ovarian cancer cells . (2013) (0)
- Abstract 384: The implications of splicing variant of AIMP2 lacking exon 2 among various cancer types: An analysis of the ICGC/TCGA database and clinical validation (2017) (0)
- Abduction of Arm Facilitates Correction of Kinked Peel-Away Sheath During Subclavian Central Line Placement. (2015) (0)
- HCC : Laparoscopic versus open Liver resection for hepatocelluar carcinoma; a case matched study (초) (2011) (0)
- A durable repair of a broken silastic catheter using a topical skin adhesive. (2011) (0)
- Environmental Life Cycle Assessment of a Novel Cultivated Meat Burger Patty in the United States (2022) (0)
- Structure of the CDB3 - ankD34 Complex from Site - Directed Spin - Labeling Studies (2009) (0)
- Aminoacyl-tRNA synthetases as therapeutic targets (2019) (0)
- Corrigendum: Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection (2017) (0)
- Structure of the Intracellular Ca2+-Binding Domain of NCX1.1 by Site Directed Spin Labeling (2011) (0)
- Landscaping the Framework of Bio Research Project - Generation of the 3D Atlas for Drug Target Discovery (2012) (0)
- Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification (2017) (0)
- Glutamyl-prolyl-tRNA synthetase 1 coordinates early endosomal anti-inflammatory AKT signaling (2022) (0)
- Assemblable project formulation for drug target discovery (2012) (0)
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