King–wai Yau

King–wai Yau's AcademicInfluence.com Rankings

King–wai Yau

Biology

#8412

World Rank

#11483

Historical Rank

Neuroscience

#1162

World Rank

#1204

Historical Rank

biology Degrees

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Biology

King–wai Yau's Degrees

PhD Neuroscience University of California, Berkeley
Bachelors Biochemistry University of British Columbia

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King–wai Yau's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity (2002) (2305)
Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN (2005) (1175)
Melanopsin and rod–cone photoreceptive systems account for all major accessory visual functions in mice (2003) (1121)
Responses of retinal rods to single photons. (1979) (844)
Central projections of melanopsin‐expressing retinal ganglion cells in the mouse (2006) (839)
Diminished Pupillary Light Reflex at High Irradiances in Melanopsin-Knockout Mice (2003) (785)
Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision (2008) (743)
Generation of three dimensional retinal tissue with functional photoreceptors from human iPSCs (2014) (676)
Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons (1990) (641)
The membrane current of single rod outer segments (1979) (590)
Cyclic GMP-activated conductance of retinal photoreceptor cells. (1989) (578)
Identification of Ligands for Olfactory Receptors by Functional Expression of a Receptor Library (1998) (564)
Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells (2007) (505)
The vitelliform macular dystrophy protein defines a new family of chloride channels (2002) (480)
Intrinsically photosensitive retinal ganglion cells. (2010) (470)
Restoration of vision after transplantation of photoreceptors (2012) (448)
Two components of electrical dark noise in toad retinal rod outer segments. (1980) (444)
Phototransduction Motifs and Variations (2009) (384)
A new subunit of the cyclic nucleotide-gated cation channel in retinal rods (1993) (358)
Phototransduction mechanism in retinal rods and cones. The Friedenwald Lecture. (1994) (352)
Calcium and light adaptation in retinal rods and cones (1988) (352)
Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment (1985) (345)
Cyclic nucleotide-gated ion channels: an extended family with diverse functions. (1996) (325)
Direct modulation by Ca2+–calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons (1994) (321)
Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells (1993) (312)
Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane (1986) (311)
Electrogenic Na–Ca exchange in retinal rod outer segment (1984) (310)
Calcium-Calmodulin Modulation of the Olfactory Cyclic Nucleotide-Gated Cation Channel (1994) (307)
Spatial spread of activation and background desensitization in toad rod outer segments (1981) (291)
Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa. (1995) (273)
Phototransduction in mouse rods and cones (2007) (266)
Photon capture and signalling by melanopsin retinal ganglion cells (2008) (263)
Light-suppressible, cyclic GMP-sensitive conductance in the plasma membrane of a truncated rod outer segment (1985) (260)
Cyclic GMP-sensitive conductance in outer segment membrane of catfish cones (1985) (243)
Melanopsin Signaling in Mammalian Iris and Retina (2011) (235)
Regulation of sensitivity in vertebrate rod photoreceptors by calcium (1996) (233)
The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry (2002) (228)
Structure-Function Analysis of the Bestrophin Family of Anion Channels* (2003) (228)
Distribution of glutamate receptor subtypes in the vertebrate retina (1995) (200)
Disruption of a Retinal Guanylyl Cyclase Gene Leads to Cone-Specific Dystrophy and Paradoxical Rod Behavior (1999) (193)
Cation selectivity of light-sensitive conductance in retinal rods (1984) (192)
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death (2013) (188)
Melanopsin-Dependent Photoreception Provides Earliest Light Detection in the Mammalian Retina (2005) (187)
Light adaptation in retinal rods of the rabbit and two other nonprimate mammals (1991) (182)
Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation. (1994) (175)
The Ca-activated Cl Channel and its Control in Rat Olfactory Receptor Neurons (2003) (166)
How vision begins: An odyssey (2008) (165)
Calcium and magnesium fluxes across the plasma membrane of the toad rod outer segment. (1988) (165)
Mechanism of the Excitatory Cl− Response in Mouse Olfactory Receptor Neurons (2005) (164)
Effect of ions on the light-sensitive current in retinal rods (1981) (163)
The Function of Guanylate Cyclase 1 and Guanylate Cyclase 2 in Rod and Cone Photoreceptors* (2007) (152)
Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1 (2005) (151)
Direct modulation by Ca(2+)-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. (1994) (149)
Elementary Response of Olfactory Receptor Neurons to Odorants (2005) (147)
Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. (2005) (140)
Retinal rods and cones have distinct G protein beta and gamma subunits. (1992) (138)
Calcium feedback and sensitivity regulation in primate rods (1991) (134)
Role of visual pigment properties in rod and cone phototransduction (2003) (133)
Receptive fields, geometry and conduction block of sensory neurones in the central nervous system of the leech. (1976) (132)
Central Role of the CNGA4 Channel Subunit in Ca2+-Calmodulin-Dependent Odor Adaptation (2001) (130)
On and Off Retinal Circuit Assembly by Divergent Molecular Mechanisms (2013) (129)
Calmodulin permanently associates with rat olfactory CNG channels under native conditions (2004) (121)
Melanopsin‐expressing ganglion cells on macaque and human retinas form two morphologically distinct populations (2016) (119)
Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications (2006) (117)
Guanosine 3',5'‐cyclic monophosphate‐activated conductance studied in a truncated rod outer segment of the toad. (1988) (116)
Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea (2015) (110)
Activation of Visual Pigments by Light and Heat (2011) (108)
Non-image-forming ocular photoreception in vertebrates (2005) (105)
Cyclic nucleotide-gated channels: an expanding new family of ion channels. (1994) (105)
Localization of the inositol 1,4,5-trisphosphate receptor in synaptic terminals in the vertebrate retina (1991) (104)
Identification of a Domain on the β-Subunit of the Rod cGMP-gated Cation Channel That Mediates Inhibition by Calcium-Calmodulin* (1998) (102)
The cGMP-phosphodiesterase and its contribution to sensitivity regulation in retinal rods (1995) (102)
Effect of ions on retinal rods from Bufo marinus. (1984) (101)
Breaking the Covalent Bond— A Pigment Property that Contributes to Desensitization in Cones (2005) (100)
Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants. (2013) (96)
Light adaptation in cat retinal rods. (1989) (94)
Light-induced fluctuations in membrane current of single toad rod outer segments (1977) (91)
Characterization of guanylate cyclase activity in single retinal rod outer segments (1995) (88)
Tracer coupling of intrinsically photosensitive retinal ganglion cells to amacrine cells in the mouse retina (2010) (86)
Olfactory marker protein modulates the cAMP kinetics of the odour‐induced response in cilia of mouse olfactory receptor neurons (2007) (80)
Loss of CNGB1 Protein Leads to Olfactory Dysfunction and Subciliary Cyclic Nucleotide-gated Channel Trapping* (2006) (79)
A rich complexity emerges in phototransduction (1993) (78)
Sodium‐dependent calcium extrusion and sensitivity regulation in retinal cones of the salamander. (1989) (75)
Cyclic GMP diffusion coefficient in rod photoreceptor outer segments. (1995) (75)
Quantal noise from human red cone pigment (2008) (72)
Signaling Properties of a Short-Wave Cone Visual Pigment and Its Role in Phototransduction (2007) (70)
Molecular Properties of Rhodopsin and Rod Function* (2007) (69)
Single‐channel measurement from the cyclic GMP‐activated conductance of catfish retinal cones. (1990) (69)
Olfactory Transduction: Tale of an unusual chloride current (1994) (69)
Guidance-Cue Control of Horizontal Cell Morphology, Lamination, and Synapse Formation in the Mammalian Outer Retina (2012) (69)
Physiological properties and receptive fields of mechanosensory neurones in the head ganglion of the leech: comparison with homologous cells in segmental ganglia. (1976) (69)
Extrasynaptic receptors on cell bodies of neurons in central nervous system of the leech. (1977) (66)
Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments. (1997) (65)
Nomenclature for Ion Channel Subunits (2001) (65)
Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide‐gated ion channel of retinal cone photoreceptors (1996) (62)
Thermal activation of the visual transduction mechanism in retinal rods (1979) (57)
Ca2+-activated Cl− Current from Human Bestrophin-4 in Excised Membrane Patches (2006) (56)
Introducing Trevor D. Lamb and Edward N. Pugh, Jr, the 2006 Recipients of the Proctor Medal (2006) (53)
Adaptation to steady light by intrinsically photosensitive retinal ganglion cells (2013) (52)
Farnesylation of Retinal Transducin Underlies Its Translocation during Light Adaptation (2005) (51)
Zinc modulation of a transient potassium current and histochemical localization of the metal in neurons of the suprachiasmatic nucleus. (1993) (50)
Intrinsic Light Response of Retinal Horizontal Cells of Teleosts (2009) (49)
Selective heteromeric assembly of cyclic nucleotide-gated channels (2003) (47)
A cGMP-gated cation channel in depolarizing photoreceptors of the lizard parietal eye (1997) (44)
In vivo gene delivery in the retina using polyethylenimine. (2007) (41)
Light responses of primate and other mammalian cones (2014) (40)
Temperature effects on the membrane current of retinal rods of the toad. (1983) (40)
Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells (2018) (39)
Phototransduction in Rods and Cones (2008) (39)
Signaling by olfactory receptor neurons near threshold (2010) (38)
Calcium and phototransduction. (2002) (36)
An unusual cGMP pathway underlying depolarizing light response of the vertebrate parietal-eye photoreceptor (1998) (35)
Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin. (1999) (35)
Functional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human. (1998) (33)
Normal Light Response, Photoreceptor Integrity, and Rhodopsin Dephosphorylation in Mice Lacking Both Protein Phosphatases with EF Hands (PPEF-1 and PPEF-2) (2001) (32)
Calcium and light adaptation in retinal photoreceptors (1991) (32)
Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes (2020) (29)
Rod Sensitivity of Neonatal Mouse and Rat (2005) (29)
Dimerization of visual pigments in vivo (2016) (27)
Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle (2017) (26)
Phototransduction Mechanism in Retinal Rods and Cones The Friedenwald Lecture (2005) (24)
Unitary response of mouse olfactory receptor neurons (2010) (24)
Spread of activation and desensitisation in rod outer segments (1980) (23)
Isolation and In Vitro Differentiation of Conditionally Immortalized Murine Olfactory Receptor Neurons (2000) (22)
Elementary response triggered by transducin in retinal rods (2019) (22)
Diffusion coefficient of the cyclic GMP analog 8-(fluoresceinyl)thioguanosine 3',5' cyclic monophosphate in the salamander rod outer segment. (1995) (20)
Mechanism of the Excitatory ClResponse in Mouse Olfactory Receptor Neurons (2005) (20)
Hattar Projections , and Intrinsic Photosensitivity Melanopsin-Containing Retinal Ganglion Cells : Architecture (2012) (20)
Deletion of GRK1 Causes Retina Degeneration through a Transducin-Independent Mechanism (2010) (19)
PHR1, a PH Domain-Containing Protein Expressed in Primary Sensory Neurons (2004) (19)
Melanopsin-expressing ganglion cells in primate retina project to the LGN and signal both color and irradiance (2004) (18)
Cyclic-nucleotide–gated cation current and Ca2+-activated Cl current elicited by odorant in vertebrate olfactory receptor neurons (2016) (18)
Study of the roles of calcium and cyclic GMP in visual transduction. (1987) (18)
Photochemical nature of parietopsin. (2012) (16)
Protein Kinase C Activity and Light Sensitivity of Single Amphibian Rods (1997) (16)
Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket (2017) (15)
PHOTOTRANSDUCTION IN RETINAL RODS AND CONES (2001) (11)
Rod Sensitivity During Xenopus Development (2002) (11)
A cGMP-gated cation channel and phototransduction in depolarizing photoreceptors of the lizard parietal eye (1998) (8)
Functional Architecture of the Photoreceptive Ganglion Cell in Primate Retina: Morphology, Mosaic Organization and Central Targets of Melanopsin Immunostained Cells (2003) (8)
Origins of direction selectivity in the primate retina (2021) (7)
Ca2+-activated Cl current predominates in threshold response of mouse olfactory receptor neurons (2018) (7)
The membrane current of single rod outer segments (1979) (7)
Two Types of Melanopsin–Containing Ganglion Cells in the Primate Retina: Links to Dopaminergic Amacrine and DB6 Cone Bipolar Cells (2006) (6)
Properties of the membrane current of rod outer segments. (1978) (6)
Study of the ionic basis of visual transduction in vertebrate retinal rods. (1985) (5)
Functional Architecture of the Photoreceptive Ganglion Cell in Primate Retina: Intrinsic Photosensitivity, S-cone Spectral Opponency and Irradiance Coding (2003) (5)
Light-dependent photoreceptor orientation in mouse retina (2020) (5)
Current fluctuations across single rod outer segments (1979) (4)
Higher Rate of Thermal Activation of Red Cone Pigments With 11–Cis A2 Compared to 11–Cis A1 Retinal as Chromophore (2005) (4)
Dark noise and retinal degeneration from D190N-rhodopsin (2020) (3)
The Ca 2 + -activated Cl − Current from Human Bestrophin-4 in Excised Membrane Patches (2006) (3)
Study of Cone Pigment Function With a Transgenic Mouse Model (2002) (3)
Sodium‐Calcium Exchange and Phototransduction in Retinal Photoreceptors a (1991) (3)
Modulation of rod cGMP-gated cation channel by calmodulin. (2000) (3)
Apo-Opsin and Its Dark Constitutive Activity across Retinal Cone Subtypes (2020) (3)
Diverse Brain Targets of Melanopsin–Expressing Retinal Ganglion Cells (2004) (2)
The cGMP-Gated Channels of Rod and Cone Photoreceptors (1990) (2)
Chapter 2 Spread of Excitation and Background Adaptation in the Rod Outer Segment (1981) (1)
Author response: Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket (2017) (1)
Novel Phototransduction Pathway in Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) (2017) (1)
Unusual phototransduction via cross-motif signaling from Gq to adenylyl cyclase in intrinsically photosensitive retinalganglion cells. (2022) (1)
Characterization of guanylyl cyclase and phosphodiesterase activities in single rod outer segments. (2000) (1)
Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells (2021) (1)
Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway (2022) (1)
On presentation of the Proctor Medal of the Association for Research in Vision and Ophthalmology to Dr. Denis A. Baylor. (1987) (1)
Functional genomic screening identifies dual leucine zipper- bearing kinase as a therapeutic target in glaucoma (2013) (1)
Role of Rod, Cone and Melanopsin–Containing Retinal Ganglion Cells in Light Detection for Non–Image–Forming Visual Functions (2005) (0)
Kinetics of the cGMP-activated channel of catfish cones. (1990) (0)
Zincmodulation ofatransient potassium current andhistochemical localization ofthemetalinneurons ofthesuprachiasmatic nucleus (1993) (0)
Opsin Phosphorylation in Rpe65–/– Mice Reduces Retinal Degeneration (2005) (0)
Sun Mechanisms On and Off Retinal Circuit Assembly by Divergent Molecular (2014) (0)
Phototransduction mechanism in depolarizing photoreceptors of lizard parietal eye (1997) (0)
Erratum: Deletion of GRK1 Causes Retina Degeneration through a Transducin-Independent Mechanism (J. Neurosci. (2010) 30:14 (2496-2503)) (2010) (0)
Introducing Marie E. Burns, the 2009 Recipient of the Cogan Award. (2010) (0)
Possible Role for Melanopsin in Photoentrainment of the Circadian Clock in Rodents (2002) (0)
Functional Expression of Human Red Cone Opsin in Xenopus Laevis Rods (2002) (0)
Title Spontaneous activation of visual pigments in relation toopenness / closedness of chromophore-binding pocket (2018) (0)
Cyclic AMP-Gated Channels and Ca-Activated Cl − Channels in Vertebrate Olfactory Receptor Cells (1994) (0)
Functional Expression of Human Rod and Cone Na/Ca–K Exchangers in Xenopus laevis Rods (2004) (0)
SunL_pages 1..9 (2013) (0)
1P-272 Photoreaction of parietopsin(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
Internal Messengers: Group Report (1986) (0)
Retinal rodsandconeshavedistinct G protein f8andysubunits (1992) (0)
Reply to Heck et al.: Signal amplification at the rhodopsin-to-transducin·phosphodiesterase step in rod phototransduction (2019) (0)
Gbeta.gama Subunits Are Required for the Normal Termination of Rod Photoresponse (2007) (0)
Kinetic Analysis of the Intermediate States of Rhodopsin and Photoresponse of Rod cells Revealed by Rhodopsin Knock-in Mouse (2003) (0)
Introducing Vadim Y. Arshavsky and Theodore G. Wensel, the 2013 recipients of the proctor medal. (2013) (0)
Deletion of Guanylate Cyclase 1 (GC1/GC–E) and Guanylate Cyclase 2 (GC2/GC–F) Eliminates Photoreceptor Function (2006) (0)
Melanopsin Signalling: Low Pigment Density, Large Single-Photon Response, and High-Efficiency Transmission (2009) (0)
Sir Alan Lloyd Hodgkin 1914–1998 (1999) (0)
Protein kinase C activity and light sensitivity of dissociated salamander rods (1997) (0)
Essential Role of Isoprenylation of Transducin in Regulation of Phototransduction in Rod Cells (2006) (0)
PHOTOTRANSDUCTION IN A DEPOLARIZING PHOTORECEPTOR OF VERTEBRATES (2001) (0)
CALCIUM AND PHOTOTRANSDUCTION 1 (2007) (0)
1Q1436 Exploring the molecular function of Parietopsin(Photobiology: Vision & Photoreception 1,The 49th Annual Meeting of the Biophysical Society of Japan) (2009) (0)
Sensory systems (2003) (0)
Constitutive Apo-Opsin Activity Across Retinal Cone Subtypes (2020) (0)
Cellular and Molecular Mechanisms of Olfaction (2001) (0)
34.1. Photoreception in the lizard parietal eye: Implications about ciliary–photoreceptor evolution (2007) (0)
1TP2-06 Exploring Molecular Functions of Parietopsin(The 47th Annual Meeting of the Biophysical Society of Japan) (2009) (0)
Gating Kinetics of the cGMP-Activated Conductance of Retinal Cones (1992) (0)
A New Cl Channel Family Defined by Vitelliform Macular Dystrophy (2003) (0)
Cyclic Nucleotide-Gated Channels: Classification, Structure and Function, Activators and Inhibitors (2000) (0)
Melanopsin Signaling: Large Single-Photon Response and Sparse Pigment (2008) (0)
Erratum: In the article Deletion of GRK1 Causes Retina Degeneration through a Transducin-Independent Mechanism by Jie Fan, Keisuke Sakurai, Ching-Kang (2010) (0)
Intrinsically Photosensitive Retinal Ganglion Cells Detect Light With a Vitamin A–Based Photopigment That is Most Likely Melanopsin (2005) (0)

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What Schools Are Affiliated With King–wai Yau?

King–wai Yau is affiliated with the following schools:

Johns Hopkins University