Kiran Musunuru
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Stem cell biologist, Perelman School of Medicine at the University of Pennsylvania
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Why Is Kiran Musunuru Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kiran Musunuru is an American cardiologist who is a Professor of Medicine at the University of Pennsylvania Perelman School of Medicine. He researches the genetics and genomics of cardiovascular and metabolic diseases. Musunuru is a leading expert in the field of gene-editing.
Kiran Musunuru's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- Common variants at 30 loci contribute to polygenic dyslipidemia (2009) (1380)
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants (2009) (1100)
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus (2010) (1048)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans (2016) (790)
- Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. (2010) (630)
- Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids (2015) (531)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
- A TALEN genome-editing system for generating human stem cell-based disease models. (2013) (518)
- Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing. (2014) (501)
- Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs. (2013) (467)
- A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice (2016) (434)
- Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
- Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. (2014) (415)
- Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing (2014) (397)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9. (2014) (330)
- Sequence-Specific RNA Binding by a Nova KH Domain Implications for Paraneoplastic Disease and the Fragile X Syndrome (2000) (326)
- Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs. (2012) (303)
- ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
- Atherogenic Dyslipidemia: Cardiovascular Risk and Dietary Intervention (2010) (275)
- Two ZBP1 KH domains facilitate β-actin mRNA localization, granule formation, and cytoskeletal attachment (2003) (250)
- In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates (2021) (247)
- Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Programming human pluripotent stem cells into white and brown adipocytes (2012) (218)
- Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. (2012) (209)
- Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
- The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. (2000) (156)
- Human Germline Genome Editing. (2017) (156)
- In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing (2017) (153)
- In utero CRISPR-mediated therapeutic editing of metabolic genes (2018) (150)
- Ion Mobility Analysis of Lipoprotein Subfractions Identifies Three Independent Axes of Cardiovascular Risk (2009) (150)
- Candidate Gene Association Resource (CARe): Design, Methods, and Proof of Concept (2010) (143)
- Clinical efficacy and safety of statins in managing cardiovascular risk (2008) (141)
- Genome editing of human pluripotent stem cells to generate human cellular disease models (2013) (138)
- The use of high-sensitivity assays for C-reactive protein in clinical practice (2008) (135)
- A Mouse Model of the Human Fragile X Syndrome I304N Mutation (2009) (132)
- Genetics of Common, Complex Coronary Artery Disease (2019) (128)
- Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis. (2016) (127)
- Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (121)
- Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci. (2017) (121)
- Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association. (2018) (118)
- Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association. (2020) (118)
- Effect of patient visualization of coronary calcium by electron beam computed tomography on changes in beneficial lifestyle behaviors. (2008) (116)
- Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. (1999) (113)
- Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. (2001) (113)
- Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. (2017) (112)
- Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins (2022) (109)
- The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines. (2009) (105)
- Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3. (2018) (93)
- CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo—Brief Report (2016) (92)
- Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. (2010) (89)
- Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries (2015) (80)
- Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group. (2010) (80)
- Association of Single Nucleotide Polymorphisms on Chromosome 9p21.3 With Platelet Reactivity: A Potential Mechanism for Increased Vascular Disease (2010) (78)
- Cell-specific RNA-binding proteins in human disease. (2003) (77)
- Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. (2016) (77)
- Genome editing in cardiovascular diseases (2017) (77)
- Stem cell models of cardiac development and disease. (2010) (76)
- Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. (2016) (71)
- Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. (2018) (69)
- In utero gene editing for monogenic lung disease (2019) (67)
- Clinical and research applications of carotid intima-media thickness. (2009) (64)
- Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. (2011) (59)
- Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement From the American Heart Association (2016) (54)
- Genetics of coronary artery disease. (2010) (53)
- Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations (2012) (51)
- Defining the spectrum of alleles that contribute to blood lipid concentrations in humans (2008) (49)
- Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project (2012) (47)
- A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation (2020) (46)
- Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells (2016) (44)
- Tunable and Reversible Substrate Stiffness Reveals a Dynamic Mechanosensitivity of Cardiomyocytes. (2019) (44)
- The Hope and Hype of CRISPR-Cas9 Genome Editing: A Review (2017) (42)
- Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. (2015) (41)
- ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. (2017) (40)
- Future Translational Applications From the Contemporary Genomics Era: A Scientific Statement From the American Heart Association (2015) (39)
- Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. (2021) (38)
- NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts (2017) (37)
- Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing (2016) (36)
- Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association (2020) (36)
- Novel Genome-Editing Tools to Model and Correct Primary Immunodeficiencies (2015) (36)
- Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. (2012) (34)
- Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes. (2019) (34)
- Genome-Edited Human Pluripotent Stem Cell–Derived Macrophages as a Model of Reverse Cholesterol Transport—Brief Report (2016) (33)
- The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction A Scientific Statement From the American Heart Association (2017) (32)
- Functional Annotation of TNNT2 Variants of Uncertain Significance With Genome-Edited Cardiomyocytes. (2018) (29)
- Determination and augmentation of RNA sequence specificity of the Nova K-homology domains. (2004) (27)
- Confirmation of Causal rs9349379-PHACTR1 Expression Quantitative Trait Locus in Human-Induced Pluripotent Stem Cell Endothelial Cells (2018) (27)
- Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice (2018) (26)
- Genome engineering tools for building cellular models of disease (2016) (25)
- Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells (2018) (25)
- Biomarkers for prediction of cardiovascular events. (2007) (24)
- Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors (2022) (24)
- Genome Editing: The Recent History and Perspective in Cardiovascular Diseases. (2017) (24)
- Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression (2015) (24)
- Genome editing in human pluripotent stem cells (2014) (23)
- Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial. (2019) (23)
- Paraneoplastic opsoclonus-myoclonus ataxia associated with non-small-cell lung carcinoma (2008) (23)
- Genome Editing for the Study of Cardiovascular Diseases (2017) (22)
- Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research. (2018) (21)
- Cardiovascular Pharmacogenomics: Current Status and Future Directions—Report of a National Heart, Lung, and Blood Institute Working Group (2012) (21)
- In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease (2021) (21)
- The clinical application of gene editing: ethical and social issues. (2019) (20)
- Angiopoietin-Like 3 (2019) (19)
- HapMap and Mapping Genes for Cardiovascular Disease (2008) (18)
- Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica (2010) (17)
- Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR / Cas 9 Graphical (2014) (17)
- Supplemental Information Protein-RNA and Protein-Protein Recognition by Dual KH 1 / 2 Domains of the Neuronal Splicing Factor Nova-1 (2011) (16)
- Cardiovascular endocrinology: Is ANGPTL3 the next PCSK9? (2017) (16)
- Active learning-based STEM education for in-person and online learning (2021) (16)
- Mapping Novel Pathways in Cardiovascular Disease Using eQTL Data: The Past, Present, and Future of Gene Expression Analysis (2013) (16)
- CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia. (2018) (16)
- Low Incidence of Off-Target Mutations in Individual CRISPR-Cas 9 and TALEN Targeted Human Stem Cell Clones Detected (2015) (14)
- Moving toward genome-editing therapies for cardiovascular diseases (2022) (14)
- What do we do now?: Responding to claims of germline gene editing in humans (2019) (14)
- Insulin-stimulated phosphatidylcholine hydrolysis, diacylglycerol/protein kinase C signalling, and hexose transport in pertussis toxin-treated BC3H-1 myocytes. (1994) (14)
- Widespread central nervous system cavernous malformations associated with café-au-lait skin lesions. Case report. (2003) (13)
- Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes. (1994) (13)
- Functional evaluation of genetic variation in complex human traits. (2012) (13)
- Medical Misinformation. (2019) (12)
- Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes (2016) (12)
- Long-term management of bilateral metastases of renal cell carcinoma to the choroid plexus (2003) (12)
- From Genotype to Phenotype: A Primer on the Functional Follow-Up of Genome-Wide Association Studies in Cardiovascular Disease (2018) (12)
- Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing. (2020) (11)
- What Do We Really Think About Human Germline Genome Editing, and What Does It Mean for Medicine? (2017) (11)
- Treatment of an anterior communicating artery aneurysm through an anomalous anastomosis from the cavernous internal carotid artery. (2002) (11)
- Candidate Gene Association Resource (CARe)Clinical Perspective (2010) (10)
- ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
- Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing (2017) (10)
- Chronobiology of Natriuretic Peptides and Blood Pressure in Lean and Obese Individuals. (2021) (10)
- How genome editing could be used in the treatment of cardiovascular diseases. (2018) (10)
- Cell cycle regulators in cancer (1997) (10)
- Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition. (2020) (10)
- Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. (2017) (10)
- Cardioprotective Effects of MTSS1 Enhancer Variants. (2019) (9)
- From Hypertrophy to Heart Failure: What Is New in Genetic Cardiomyopathies (2019) (9)
- Turning up the Heat with Therapeutic Epigenome Editing. (2018) (9)
- Medical Misinformation: Vet the Message! (2019) (8)
- Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects (2021) (8)
- Enduring mystery of the chromosome 9p21.3 locus. (2013) (8)
- Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. (2018) (7)
- Personalized genomes and cardiovascular disease. (2014) (7)
- High-Throughput Screening and CRISPR-Cas9 Modeling of Causal Lipid-Associated Expression Quantitative Trait Locus Variants (2016) (7)
- Improving Genomic Literacy Among Cardiovascular Practitioners via a Flipped-Classroom Workshop at a National Meeting. (2016) (7)
- Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (6)
- (Pro)renin Receptor and LDL Clearance: An Old Player Joins A New Game. (2016) (6)
- Self‐Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene (2020) (6)
- Natriuretic Peptide Deficiency in Obese Individuals: Mechanistic Insights From Healthy Organ Donor Cohort. (2021) (6)
- CHAPTER 13 – Use of High-Sensitivity C-Reactive Protein for Risk Assessment (2009) (5)
- Regulatory elements in noncoding DNA in the chromosome 9p21 locus. (2011) (5)
- Therapeutic application of genome editing in dyslipidemia (2021) (4)
- EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression (2019) (4)
- A synergistic relationship of elevated low-density lipoprotein cholesterol levels and systolic blood pressure with coronary artery calcification. (2008) (4)
- Medical Misinformation: Vet the Message! (2019) (4)
- Lipid nanoparticles incorporating a GalNAc ligand enable in vivo liver ANGPTL3 editing in wild-type and somatic LDLR knockout non-human primates (2021) (4)
- Translating Research into Therapies (2012) (4)
- Lack of association of KIF6 genotype with vascular disease and statin response. (2011) (4)
- CRISPR and Cardiovascular Diseases. (2022) (4)
- The Implications of the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression Trial: A Return to First Principles (2008) (4)
- RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion (2018) (4)
- Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells. (2018) (3)
- Genetics and Genomics of Atherosclerotic Cardiovascular Disease (2020) (3)
- Adipocyte-specific modulation of KLF14 expression in mice leads to sex-dependent impacts in adiposity and lipid metabolism (2021) (3)
- Challenges and advances of CRISPR-Cas9 genome editing in therapeutics (2019) (3)
- Medical Misinformation: Vet the Message! (2019) (2)
- Top advances in functional genomics and translational biology for 2011. (2012) (2)
- CRISPR Hits Home in a First-in-Human Study. (2021) (2)
- Therapeutic genome editing (2021) (2)
- Medical misinformation: vet the message! (2019) (2)
- Why Human Embryo Editing Should Be Banned. (2019) (2)
- Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins (2018) (2)
- Abstract 70: KLF14 is a Novel Regulator of Human Metabolism (2014) (2)
- Evaluating the contribution of cell-type specific alternative splicing to variation in lipid levels (2019) (2)
- BRCA1/2 Mutations and Cardiovascular Function in Breast Cancer Survivors (2022) (1)
- Transforming growth factor β2 mutations and familial thoracic aortic aneurysms. (2012) (1)
- Medical misinformation: Vet the message! (2019) (1)
- Current Role of Pharmacogenomics in Cardiovascular Medicine (2011) (1)
- Randomized controlled studies comparing traditional lectures versus online modules (2021) (1)
- ANGPTL3 De fi ciency and Protection Against Coronary Artery Disease (1)
- Medical Misinformation. (2019) (1)
- Induction of cardiomyocytes from cardiac fibroblasts. (2012) (1)
- Base editing (2021) (1)
- Reply: Loss-of-Function Mutations to Estimate Pharmacological ANGPTL3 Inhibition. (2017) (1)
- Base editing: a brief review and a practical example (2020) (1)
- In This Issue: March. (2018) (1)
- Stem cell modeling of lipid genetics (2018) (1)
- Choosing a nuclease, guide RNA, and repair template (2021) (0)
- Medical Misinformation. (2019) (0)
- CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN (2000) (0)
- In utero CRISPR-mediated therapeutic editing of metabolic genes (2018) (0)
- Abstract 498: Functional Annotation of TNNT2 Variants of Uncertain Significance With Induced Pluripotent Stem Cell-derived Cardiomyocytes (2018) (0)
- Genome editing for functional experiments and screens (2021) (0)
- Reprogramming of hepatic lipoprotein metabolism by small molecule inducers of TRIB1 expression (998.1) (2014) (0)
- Abstract 240: Predictive and Experimental Modeling of Bag3-associated Cardiomyocyte Dysfunction (2018) (0)
- Top advances in functional genomics and translational biology for 2012. (2013) (0)
- Detoxifying chemotherapy with genetics-guided stem cell modeling: A personalized affair. (2021) (0)
- Safety, Health and Environment (2014) (0)
- Short title: Musunuru et al; Design of NHLBI CARe (2017) (0)
- Correcting tyrosinaemia via a point mutation (2020) (0)
- Abstract 18960: RNA-binding Protein A1CF Modulates Plasma Triglyceride Levels Through Transcriptomic Regulation of Stress-Induced VLDL Secretion (2017) (0)
- Medical Misinformation. (2019) (0)
- Abstract 97: Genotype to Phenotype: Function of Common Noncoding and Rare Coding Variants In ANGPTL3 (2017) (0)
- Abstract 013: Genotype to Phenotype: Function of Rare Coding Variants in ANGPTL3 (2018) (0)
- CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN (2000) (0)
- Adenine base editing to treat progeria syndrome and extend the lifespan (2021) (0)
- List of Contributors (2020) (0)
- Crystal structure (I) of Nova-1 KH1/KH2 domain tandem with 25 nt RNA hairpin (2006) (0)
- Abstract 157: Alternative Splicing of PLD1 and Its Role in Modulating Inflammatory Phenotypes in Primary Human Macrophages (2016) (0)
- 481. CRISPR/Cas9-Mediated In Vivo Genome Editing to Correct the OTC spfash Mutation in Newborn Mice (2016) (0)
- Leveraging CRISPR/Cas Genome Editing Technology to Identify and Characterize Causal GWAS Variants for Blood Lipids (2018) (0)
- Alternative types of editing (2021) (0)
- Protein-6 and Coronary Artery Disease in 19 Case-Control Studies Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like (2012) (0)
- Methods in Genetics and Clinical Interpretation HapMap and Mapping Genes for Cardiovascular Disease (2008) (0)
- Medical Misinformation: Vet the Message! (2019) (0)
- Abstract 15407: Humanity in a Dish: Investigating a Common Genetic Basis for Human Metabolic Disease With Induced Pluripotent Stem Cells (2016) (0)
- Kiran Musunuru Induction of Cardiomyocytes From Cardiac Fibroblasts (2012) (0)
- What do we do now?: Responding to claims of germline gene editing in humans (2019) (0)
- CRISPR/Cas9 screens implicate RARA and SPNS1 in doxorubicin cardiotoxicity (2022) (0)
- SORTI: deciphering the biological and genetic link between cholesterol and coronary heart disease (2010) (0)
- Identification of a growth factor that rejuvenates the heart. (2013) (0)
- Assessing for off-target mutagenesis (2021) (0)
- Correcting tyrosinaemia via a point mutation (2020) (0)
- Medical Misinformation. (2019) (0)
- High-throughput Screening and CRISPR-Cas 9 Modeling of Causal Lipid-associated 1 Expression Quantitative Trait Locus Variants 2 3 (2016) (0)
- A brief history and primer on genome editing (2021) (0)
- Choosing a genome editing strategy and target site (2021) (0)
- Assessing the outcomes of genome editing (2021) (0)
- Exome sequencing to identify novel genes in hypertension. (2012) (0)
- on a National Heart, Lung and Blood Institute Working Group Guided Antithrombotic Therapy: Current Status and Future Research Direction: Report (2014) (0)
- Past Successes of Genetic Findings Familial Hypercholesterolemia and Low-Density Lipoprotein Cholesterol Lowering (2015) (0)
- The Stroke Genetics Network: living up to its potential. (2013) (0)
- Cardiovascular Genetics : A News Round-Up Omics Gets Personal Integrative Profiling of Health and Disease (2012) (0)
- Medical misinformation: vet the message! (2019) (0)
- Efficient prime editing in mouse brain, liver and heart with dual AAVs. (2023) (0)
- Medical Misinformation. (2019) (0)
- Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors (2022) (0)
- Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (0)
- Genome editing for cellular disease modeling (2021) (0)
- Abstract 11154: Cardioprotective Effects of Mtss1 Reduction Iin Dilated Cardiomyopathy (2021) (0)
- Abstract 27: Therapeutic Targeting of Human Lipid Genes With in vivo CRISPR-Cas9 Genome Editing (2015) (0)
- Abstract 55: Disruption of PCSK9 Using a Targeted Base Editing Strategy (2017) (0)
- Do Evidence-Based Clinical Guidelines Do More Harm Than Good? (2011) (0)
- Leading Edge Review GeneticsofCommon , ComplexCoronaryArteryDisease (2019) (0)
- Cardiomyopathy During A Partial Molar Pregnancy (2022) (0)
- Abstract # 10083: From Genotype to Phenotype at a Novel Cholesterol and Myocardial Infarction Locus (2010) (0)
- Medical Misinformation - Vet the Message! (2019) (0)
- Figure 3, Generic TALEN amino acid sequences (to recognize 15 bp DNA sequences). (2013) (0)
- An Overview of Genome Editing in Cardiovascular and Metabolic Diseases. (2023) (0)
- Abstract 5: Sortilin Regulates Hepatic VLDL Secretion and LDL Uptake in a Lysosome-Dependent Manner (2012) (0)
- Abstract 125: Reversible Epigenome Editing Of PCSK9 As A Therapeutic Strategy (2022) (0)
- Scientists on the Spot: The future of genome editing in cardiovascular medicine (2019) (0)
- Supplementary Material (nature09270-s1) (2012) (0)
- Medical Misinformation. (2019) (0)
- ION Mobility Analysis Of Lipoprotein Subfractions Suggests Three Independent Mechanisms Of Cardiovascular Risk (2009) (0)
- A TALEN genome editing system to generate human stem cell-based disease models (2013) (0)
- Novel Genes for Dyslipidemias: Genome-Wide Association Studies (2015) (0)
- Figure 1, Overview of hPSC TALEN genome editing process. (2013) (0)
- Ongoing Promises and Public Expectations of the HGP (0)
- Deciphering Cardiovascular Genomics and How They Apply to Cardiovascular Disease Prevention (2018) (0)
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Myocardial Infarction Genetics Consortium * (2009) (0)
- Genome editing of a CArG element in the mouse genome establishes its role in gene expression. (2015) (0)
- Figure 2, Example genome editing target site showing TALEN design criteria. (2013) (0)
- Abstract 1438: Myocardial Infarction Associated SNPs on Chromosome 9p21.3 are Associated with Coronary Artery Calcification but Not Carotid Intimal Medial Thickness in the Amish (2008) (0)
- Abstract 21: Sortilin Is a Novel Mediator of Cellular Low-Density Lipoprotein Uptake (2012) (0)
- Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (2018) (0)
- ASHG POSITION STATEMENT Human Germline Genome Editing (2017) (0)
- Abstract 18593: Use of a CRISPR/Cas System for Cardiovascular Disease Modeling and Therapeutic Applications (2013) (0)
- Figure 4, Representative FACS plots illustrating isolation of TALEN expressing hESCs. (2013) (0)
- Abstract 242: Functional Characterization of a Cis-eQTL Locus for Plasma Cholesterol Using CRISPR/Cas Genome Editing in Human Pluripotent Stem Cells (2014) (0)
- Abstract 17325: Obesity, Blood Pressure, and Diurnal Variation in Natriuretic Peptides: A Clinical Trial (2020) (0)
- Genetics of Cardiovascular Disease and Its Role in Risk Prediction (2011) (0)
- Medical misinformation: vet the message! (2019) (0)
- The use of ZFNs , TALENs , and CRISPR-Cas 9 for precision genome editing in mammals (2015) (0)
- In This Issue: April. (2018) (0)
- Abstract 214: Functional Analysis of the Low Density Lipoprotein Receptor Using Saturation Mutagenesis Strategies (2018) (0)
- Figure 5, Representative images showing the expansion and screening of hESC lines during the genome editing process. (2013) (0)
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