Kiyofumi Yamada

Q: What Schools Are Affiliated With Kiyofumi Yamada

Kiyofumi Yamada is affiliated with the following schools: Kanazawa University, University of Tokyo, Nagoya University, Institute of Science Tokyo, Kyoto University

Kiyofumi Yamada's AcademicInfluence.com Rankings

Kiyofumi Yamada

Computer Science

#6522

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#6875

Historical Rank

Computational Linguistics

#1143

World Rank

#1157

Historical Rank

Machine Learning

#2146

World Rank

#2174

Historical Rank

Artificial Intelligence

#2408

World Rank

#2449

Historical Rank

computer-science Degrees

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Computer Science

Kiyofumi Yamada's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Kiyofumi Yamada's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

CD38 is critical for social behaviour by regulating oxytocin secretion (2007) (609)
Brain-derived neurotrophic factor/TrkB signaling in memory processes. (2003) (535)
Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats (2000) (473)
Role for brain-derived neurotrophic factor in learning and memory. (2002) (367)
Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress (2003) (272)
Protective effects of idebenone and α‐tocopherol on β‐amyloid‐(1–42)‐induced learning and memory deficits in rats: implication of oxidative stress in β‐amyloid‐induced neurotoxicity in vivo (1999) (234)
Production and functions of IL-17 in microglia (2008) (215)
Social isolation rearing‐induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion‐related behaviors in juvenile mice (2008) (215)
CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning (2002) (208)
Behavioral abnormality and pharmacologic response in social isolation-reared mice (2009) (195)
Animal models of Alzheimer's disease and evaluation of anti-dementia drugs. (2000) (186)
Involvement of BDNF receptor TrkB in spatial memory formation. (2003) (183)
Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. (2007) (178)
Simultaneous Measurement of Nitrite and Nitrate Levels as Indices of Nitric Oxide Release in the Cerebellum of Conscious Rats (1997) (167)
Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain (1995) (167)
β-Amyloid (1–42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex (2004) (162)
Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation (2003) (161)
Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: a new model of schizophrenia (1995) (160)
Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus (2011) (156)
Role of Tumor Necrosis Factor-α in Methamphetamine-Induced Drug Dependence and Neurotoxicity (2004) (149)
Repeated Methamphetamine Treatment Impairs Recognition Memory Through a Failure of Novelty-Induced ERK1/2 Activation in the Prefrontal Cortex of Mice (2006) (149)
Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood (2010) (142)
A Role of Fos Expression in the CA3 Region of the Hippocampus in Spatial Memory Formation in Rats (2002) (137)
Stress-induced behavioral responses and multiple opioid systems in the brain (1995) (137)
Chronic restraint stress impairs neurogenesis and hippocampus‐dependent fear memory in mice: possible involvement of a brain‐specific transcription factor Npas4 (2010) (136)
Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-α gene: implications for emotional behavior (2000) (132)
Combined effects of hypoxia, hyperkalemia and acidosis on membrane action potential and excitability of guinea-pig ventricular muscle. (1984) (132)
Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. (2011) (130)
Mechanism of systemically injected interferon-alpha impeding monoamine biosynthesis in rats: role of nitric oxide as a signal crossing the blood–brain barrier (2003) (128)
Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease. (2005) (128)
Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats. (1999) (127)
Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice (2011) (122)
Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood (2009) (120)
Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats (1998) (119)
Hyperfunction of Dopaminergic and Serotonergic Neuronal Systems in Mice Lacking the NMDA Receptor ε1 Subunit (2001) (116)
FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization (2015) (116)
The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice. (1996) (114)
The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release. (2004) (112)
Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of Alzheimer’s disease (2015) (110)
Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice (1996) (107)
Regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors. (2004) (107)
Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. (2014) (104)
Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD) (2015) (104)
Peripheral-type benzodiazepine receptors are involved in the regulation of cholesterol side chain cleavage in adrenocortical mitochondria. (1989) (102)
Prostaglandin E receptor EP1 controls impulsive behavior under stress. (2005) (101)
Amyloid β‐peptide induces nitric oxide production in rat hippocampus: association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors (2001) (99)
Antiamnesic and Neuroprotective Effects of the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid β25–35-Induced Toxicity in Mice (2009) (98)
α7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in β-amyloid infused rats (2006) (95)
Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity. (2004) (94)
Effects of the novel antipsychotic agent 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro -2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland. (1996) (93)
Improvement by nefiracetam of β‐amyloid‐(1‐42)‐induced learning and memory impairments in rats (1999) (92)
Role of the mesotelencephalic dopamine system in learning and memory processes in the rat. (2003) (92)
Restraining tumor necrosis factor-alpha by thalidomide prevents the Amyloid beta-induced impairment of recognition memory in mice (2008) (88)
Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse (2013) (88)
Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivo. (1999) (87)
Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice (2008) (84)
Memory deficits and increased emotionality induced by β-amyloid (25–35) are correlated with the reduced acetylcholine release and altered phorbol dibutyrate binding in the hippocampus (2001) (84)
Immunocytochemical evidence that amyloid β (1–42) impairs endogenous antioxidant systems in vivo (2003) (83)
Dissociation of impairment between spatial memory, and motor function and emotional behavior in aged rats (1998) (82)
Lower Sensitivity to Stress and Altered Monoaminergic Neuronal Function in Mice Lacking the NMDA Receptor ε4 Subunit (2002) (81)
Disrupted Transforming Growth Factor-β Signaling in Spinal and Bulbar Muscular Atrophy (2010) (81)
Brain dysfunction associated with an induction of nitric oxide synthase following an intracerebral injection of lipopolysaccharide in rats (1999) (80)
Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid β-peptide-induced cholinergic dysfunction (2003) (78)
Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit. (2001) (78)
The Gln27Glu beta2-adrenergic receptor variant is associated with obesity due to subcutaneous fat accumulation in Japanese men. (1999) (77)
Involvement of Pallidotegmental Neurons in Methamphetamine- and MK-801-Induced Impairment of Prepulse Inhibition of the Acoustic Startle Reflex in Mice: Reversal by GABAB Receptor Agonist Baclofen (2008) (77)
Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment (2010) (76)
ROLE OF INDUCIBLE NITRIC OXIDE SYNTHASE IN (2002) (75)
Different subtypes of GABAB receptors are present at pre- and postsynaptic sites within the rat dorsolateral septal nucleus. (1999) (75)
Reduction of methamphetamine‐induced sensitization and reward in matrix metalloproteinase‐2 and ‐9‐deficient mice (2006) (75)
Matrix Metalloprotease-9 Inhibition Improves Amyloid β-Mediated Cognitive Impairment and Neurotoxicity in Mice (2009) (74)
Clozapine prevents a decrease in neurogenesis in mice repeatedly treated with phencyclidine. (2007) (74)
Decreased interleukin-6 level in the cerebrospinal fluid of patients with Alzheimer-type dementia (1995) (74)
Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo (2016) (73)
Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats (2005) (73)
Mutual regulation between the intercellular messengers nitric oxide and brain‐derived neurotrophic factor in rodent neocortical neurons (1999) (70)
Girdin Phosphorylation Is Crucial for Synaptic Plasticity and Memory: A Potential Role in the Interaction of BDNF/TrkB/Akt Signaling with NMDA Receptor (2014) (70)
MAGE-D1 Regulates Expression of Depression-Like Behavior through Serotonin Transporter Ubiquitylation (2012) (69)
Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine‐induced behavioral sensitization and reward: implications for dopamine receptor down‐regulation and dopamine release (2007) (69)
Propentofylline improves learning and memory deficits in rats induced by beta-amyloid protein-(1-40). (1998) (68)
Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats (1996) (68)
Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol (2007) (67)
Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors (2017) (66)
The Rewards of Nicotine: Regulation by Tissue Plasminogen Activator–Plasmin System through Protease Activated Receptor-1 (2006) (66)
Methamphetamine use causes cognitive impairment and altered decision-making (2019) (65)
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin. (1994) (64)
Effect of lesions in the striatum, nucleus accumbens and medial raphe on phencyclidine-induced stereotyped behaviors and hyperactivity in rats. (1983) (64)
Matrix Metalloproteinases Contribute to Neuronal Dysfunction in Animal Models of Drug Dependence, Alzheimer's Disease, and Epilepsy (2011) (63)
Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo (1997) (63)
Involvement of Nitric Oxide in Pentylenetetrazole‐Induced Kindling in Rats (2000) (62)
Sex-dependent differences in the pharmacological actions and pharmacokinetics of phencyclidine in rats. (1984) (60)
Neural Circuits Containing Pallidotegmental GABAergic Neurons are Involved in the Prepulse Inhibition of the Startle Reflex in Mice (2007) (60)
Role of nitric oxide in the effect of aging on spatial memory in rats (1997) (59)
alpha7 Nicotinic acetylcholine receptor as a target to rescue deficit in hippocampal LTP induction in beta-amyloid infused rats. (2006) (59)
Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. (2004) (59)
Neuronal mechanism of nociceptin-induced modulation of learning and memory: Involvement of N-methyl-D-aspartate receptors (2003) (58)
Effects of σ 1 receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats (2000) (57)
Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor ε1 subunit (2004) (57)
Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N‐methyl‐D‐aspartate receptors composed of an NR1/NR2B subunit assembly (2009) (57)
Enduring vulnerability to reinstatement of methamphetamine‐seeking behavior in glial cell line‐derived neurotrophic factor mutant mice (2007) (57)
Long‐term deprivation of oestrogens by ovariectomy potentiates β‐amyloid‐induced working memory deficits in rats (1999) (57)
Fustin flavonoid attenuates β‐amyloid (1–42)‐induced learning impairment (2009) (56)
Protective potential of IL-6 against trimethyltin-induced neurotoxicity in vivo. (2012) (56)
The role of tissue plasminogen activator in methamphetamine‐related reward and sensitization (2005) (55)
Lower sensitivity to stress and altered monoaminergic neuronal function in mice lacking the NMDA receptor epsilon 4 subunit. (2002) (55)
Amyloid β-peptide induces cholinergic dysfunction and cognitive deficits: a minireview (2002) (54)
Interaction of BDNF/TrkB signaling with NMDA receptor in learning and memory. (2004) (53)
Involvement of cyclic AMP systems in morphine physical dependence in mice: prevention of development of morphine dependence by rolipram, a phosphodiesterase 4 inhibitor (2001) (52)
Anti-dementia Activity of Nobiletin, a Citrus Flavonoid: A Review of Animal Studies (2014) (52)
Evaluation of emotional behaviors in young offspring of C57BL/6J mice after gestational and/or perinatal exposure to nicotine in six different time-windows (2013) (51)
Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems. (2010) (51)
GABAB receptor agonist baclofen improves methamphetamine-induced cognitive deficit in mice. (2009) (49)
Orally active NGF synthesis stimulators: potential therapeutic agents in alzheimer's disease (1997) (49)
Correlation of CYP2C19 Phenotype With Voriconazole Plasma Concentration in Children (2013) (49)
Alterations of GABAergic and dopaminergic systems in mutant mice with disruption of exons 2 and 3 of the Disc1 gene (2014) (48)
Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment (2011) (48)
Changes in NMDA receptor/ nitric oxide signaling pathway in the brain with aging (1998) (48)
Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice (2013) (48)
Involvement of nitric oxide in phencyclidine-induced hyperlocomotion in mice. (1995) (47)
New generation dihydropyridine calcium entry blockers: in search of greater selectivity for one tissue subtype. (1989) (47)
Spatial memory deficit and neurodegeneration induced by the direct injection of okadaic acid into the hippocampus in rats (2001) (47)
Evaluation of object-based attention in mice (2011) (46)
Protective effect of interleukin-6 against the death of PC12 cells caused by serum deprivation or by the addition of a calcium ionophore. (1996) (46)
Memory impairment induced by chronic intracerebroventricular infusion of beta-amyloid (1–40) involves downregulation of protein kinase C (2002) (46)
The structures of evonine and neoevonine alkaloids obtained from Euonymus Sieboldiana blume (1973) (46)
Neuropsychotoxicity of abused drugs: involvement of matrix metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioral sensitization and reward in rodents. (2008) (45)
Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels. (2002) (45)
The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (σ) receptor ligands involves both σ1 and σ2 sites (1999) (45)
Aberrant expression and mutations of TGF-beta receptor type II gene in endometrial cancer. (2005) (44)
A Novel Azaindolizinone Derivative ZSET1446 (Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one) Improves Methamphetamine-Induced Impairment of Recognition Memory in Mice by Activating Extracellular Signal-Regulated Kinase 1/2 (2007) (44)
Evaluation of cognitive behaviors in young offspring of C57BL/6J mice after gestational nicotine exposure during different time-windows (2013) (43)
Total synthesis of (±)-patchouli alcohol and (±)-seychellene via a common homoisotwistane intermediate (1979) (43)
A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress. (2007) (43)
Changes in muscarinic cholinergic, PCP, GABAA, D1, and 5-HT2A receptor binding, but not in benzodiazepine receptor binding in the brains of aged rats. (1994) (42)
The Risk Factors of Severe Acute Kidney Injury Induced by Cisplatin (2013) (42)
Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor. (2014) (42)
Phencyclidine-induced stereotyped behaviors in rats following specific neurotoxin lesions of the striatum. (1983) (42)
St. John's Wort (Hypericum perforatum) induces overexpression of multidrug resistance protein 2 (MRP2) in rats: a 30-day ingestion study. (2004) (42)
γ-aminobutyric acid and taurine antagonize the central effects of angiotensin II and renin on the intake of water and salt, and on blood pressure in rats (1988) (41)
Effects of nicotine on memory impairment induced by blockade of muscarinic, nicotinic and dopamine D2 receptors in rats. (2003) (41)
A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels in guinea pig ileum. (1994) (41)
Npas4 regulates Mdm2 and thus Dcx in experience-dependent dendritic spine development of newborn olfactory bulb interneurons. (2014) (40)
NC-1900, an active fragment analog of arginine vasopressin, improves learning and memory deficits induced by beta-amyloid protein in rats. (1998) (40)
Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis (2018) (40)
Drug dependence, synaptic plasticity, and tissue plasminogen activator. (2005) (40)
Insular neural system controls decision-making in healthy and methamphetamine-treated rats (2015) (40)
Animal model for schizophrenia that reflects gene-environment interactions. (2011) (39)
Sigma receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats. (1998) (39)
The roles of glial cell line-derived neurotrophic factor, tumor necrosis factor-alpha, and an inducer of these factors in drug dependence. (2007) (39)
Isolation and structures of a new alkaloid alatamine and an insecticidal alkaloid wilfordine from euonymus alatus forma striatus (thunb.) makino. (1978) (39)
ω-conotoxin GVIA protects against ischemia-induced neuronal death in the Mongolian gerbil but not against quinolinic acid-induced neurotoxicity in the rat (1994) (38)
Protective Potential of the Glutathione Peroxidase-1 Gene in Abnormal Behaviors Induced by Phencyclidine in Mice (2017) (37)
Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes (2018) (37)
Role of nitric oxide in the development of tolerance and sensitization to behavioural effects of phencyclidine in mice (1996) (37)
Pro‐ and Anti‐Addictive Neurotrophic Factors and Cytokines in Psychostimulant Addiction: Mini Review (2004) (36)
Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex (2016) (36)
Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice: An in vivo microdialysis study (2010) (36)
Genetic diversity of clinical Mycobacterium avium subsp. hominissuis and Mycobacterium intracellulare isolates causing pulmonary diseases recovered from different geographical regions. (2015) (36)
Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of beta-amyloid in rats. (2000) (36)
A selective phosphodiesterase IV inhibitor, rolipram blocks both withdrawal behavioral manifestations, and c-Fos protein expression in morphine dependent mice (2001) (35)
Blonanserin Ameliorates Phencyclidine-Induced Visual-Recognition Memory Deficits: the Complex Mechanism of Blonanserin Action Involving D3-5-HT2A and D1-NMDA Receptors in the mPFC (2015) (35)
Cytokine Receptor-Like Factor 1 is Highly Expressed in Damaged Human Knee Osteoarthritic Cartilage and Involved in Osteoarthritis Downstream of TGF-β (2009) (35)
Cardiovascular Effects of FR34235, a New Dihydropyridine Slow Channel Blocker, in Isolated Rabbit Myocardium and Aorta (1983) (35)
Regulation of nerve growth factor release by nitric oxide through cyclic GMP pathway in cortical glial cells. (1999) (35)
Involvement of Matrix Metalloproteinase-Mediated Proteolysis of Neural Cell Adhesion Molecule in the Development of Cerebral Ischemic Neuronal Damage (2011) (35)
Substance P suppresses GABAA receptor function via protein kinase C in primary sensory neurones of bullfrogs. (1996) (35)
Effect of Dietary Fiber on Morphine-induced Constipation in Rats (2002) (34)
Enhanced antidepressant efficacy of σ1 receptor agonists in rats after chronic intracerebroventricular infusion of β-amyloid-(1–40) protein (2004) (34)
Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunit. (2004) (34)
Relapse of methamphetamine-seeking behavior in C57BL/6J mice demonstrated by a reinstatement procedure involving intravenous self-administration (2006) (34)
Expression of estrogen receptor-β in the postischemic monkey hippocampus (2004) (33)
Transient drug-primed but persistent cue-induced reinstatement of extinguished methamphetamine-seeking behavior in mice (2007) (33)
Involvement of matrix metalloproteinase-9 in the development of morphine tolerance. (2012) (33)
Additive effects of nicorandil on coronary blood flow during continuous administration of nitroglycerin. (2001) (33)
Neuronal Per Arnt Sim (PAS) Domain Protein 4 (NPAS4) Regulates Neurite Outgrowth and Phosphorylation of Synapsin I* (2012) (33)
Absence of SHATI/Nat8l reduces social interaction in mice (2012) (33)
Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion. (2014) (33)
Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules (2013) (33)
Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. (2009) (32)
Learning and memory in two different reward tasks in a radial arm maze in rats (2002) (32)
Transcriptional suppression of the neuronal PAS domain 4 (Npas4) gene by stress via the binding of agonist‐bound glucocorticoid receptor to its promoter (2012) (32)
Transient suppression of progenitor cell proliferation through NMDA receptors in hippocampal dentate gyrus of mice with traumatic stress experience (2008) (32)
Possible involvement of nitric oxide in quinolinic acid-induced convulsion in mice (1995) (32)
Neurotoxicity induced by continuous infusion of quinolinic acid into the lateral ventricle in rats (1990) (31)
Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia (2018) (31)
Possible Involvement of Catalase in the Protective Effect of Interleukin-6 Against 6-Hydroxydopamine Toxicity in PC12 Cells (1997) (31)
AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication (2019) (31)
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice (1985) (30)
Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory (2015) (30)
Exposure to extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine D1-like receptors in mice. (2007) (30)
Alteration of gene expression and DNA methylation in drug-resistant gastric cancer. (2014) (30)
Suppression of neurocognitive damage in LP‐BM5‐infected mice with a targeted deletion of the TNF‐α gene (2000) (29)
Gene-wide association study between the methylenetetrahydrofolate reductase gene (MTHFR) and schizophrenia in the Japanese population, with an updated meta-analysis on currently available data (2010) (29)
Effects of nefiracetam on drug-induced impairment of latent learning in mice in a water finding task. (1994) (29)
Protein Kinase Cδ Gene Depletion Protects Against Methamphetamine-Induced Impairments in Recognition Memory and ERK1/2 Signaling via Upregulation of Glutathione Peroxidase-1 Gene (2017) (28)
Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. (2019) (28)
Pharmacist-managed clinics for patient education and counseling in Japan: current status and future perspectives (2015) (28)
Roles of Matrix Metalloproteinases and Their Targets in Epileptogenesis and Seizures (2013) (28)
KDIGO (Kidney Disease: Improving Global Outcomes) Criteria Could Be a Useful Outcome Predictor of Cisplatin-Induced Acute Kidney Injury (2012) (28)
Electrical and Mechanical Effects of Amrinone on Isolated Guinea Pig Ventricular Muscle (1983) (27)
Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia. (2012) (27)
Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia (2015) (26)
Parishin C attenuates phencyclidine-induced schizophrenia-like psychosis in mice: involvements of 5-HT1A receptor. (2010) (26)
Amyloid pathology and protein kinase C (PKC): possible therapeutics effects of PKC activators. (2005) (26)
Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus (2020) (26)
Modification by the tissue plasminogen activator–plasmin system of morphine‐induced dopamine release and hyperlocomotion, but not anti‐nociceptive effect in mice (2005) (26)
Role of convergent activation of glutamatergic and dopaminergic systems in the nucleus accumbens in the development of methamphetamine psychosis and dependence. (2013) (26)
Possible involvement of protease‐activated receptor‐1 in the regulation of morphine‐induced dopamine release and hyperlocomotion by the tissue plasminogen activator‐plasmin system (2007) (26)
Solubilization and Characterization of a [3H]Hemicholinium‐3 Binding Site in Rat Brain (1988) (25)
Synergistic effects of adenosine A2A antagonist and L-DOPA on rotational behaviors in 6-hydroxydopamine-induced hemi-Parkinsonian mouse model. (2007) (25)
The Extensive Nitration of Neurofilament Light Chain in the Hippocampus Is Associated with the Cognitive Impairment Induced by Amyloid β in Mice (2008) (24)
Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits (2015) (24)
Substance K, a novel tachykinin injected bilaterally into the ventral tegmental area of rats increases behavioral response. (1985) (24)
Isolation and structures of euonymine and neoeuonymine, alkaloids from Euonymus Sieboldiana blume (1977) (24)
A new nomenclature for classifying psychotropic drugs. (2017) (23)
An Environmental and Biological Study of Occupational Exposure to Cyclophosphamide in the Pharmacy of a Japanese Community Hospital Designated for the Treatment of Cancer (2009) (23)
Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence (2012) (23)
Expression of estrogen receptor-beta in the postischemic monkey hippocampus. (2004) (23)
Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons (2019) (23)
Discriminative-stimulus effects of methamphetamine and morphine in rats are attenuated by cAMP-related compounds (2006) (23)
ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk (2020) (22)
Changes in ciliary neurotrophic factor content in the rat brain after continuous intracerebroventricular infusion of β-amyloid(1–40) protein (1995) (22)
Neuropharmacological characterization of voltage-sensitive calcium channels: possible existence of neomycin-sensitive, omega-conotoxin GVIA- and dihydropyridines-resistant calcium channels in the rat brain. (1993) (22)
Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. (2011) (22)
The hydrophobic dipeptide Leu–Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF (2011) (22)
Endogenous modulators for drug dependence. (2008) (22)
Contribution of different opioid systems to footshock-induced analgesia and motor suppression. (1983) (22)
Involvement of hippocampal extracellular signal-regulated kinase 1/2 in spatial working memory in rats (2006) (22)
Involvement of Tissue Plasminogen Activator-Plasmin System in Depolarization-Evoked Dopamine Release in the Nucleus Accumbens of Mice (2006) (22)
Perspectives of pharmacotherapy in Alzheimer's disease. (1999) (21)
The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites. (1999) (21)
Overexpression of piccolo C2A domain induces depression-like behavior in mice (2010) (21)
Characterization of learning and memory deficits in C57BL/6 mice infected with LP-BM5, a murine model of AIDS (1999) (21)
Pharmacologic Treatment with GABAB Receptor Agonist of Methamphetamine-Induced Cognitive Impairment in Mice (2011) (21)
Effects of sigma receptor agonists on the impairment of spontaneous alternation behavior and decrease of cyclic GMP level induced by nitric oxide synthase inhibitors in mice (2000) (21)
The chondroprotective agent ITZ-1 inhibits interleukin-1beta-induced matrix metalloproteinase-13 production and suppresses nitric oxide-induced chondrocyte death. (2009) (21)
Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome. (2012) (21)
Risperidone prevents the development of supersensitivity, but not tolerance, to phencyclidine in rats treated with subacute phencyclidine. (1995) (21)
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Optimization of operant test for testing risky decision-making in mice (2019) (0)
[Role of cytokines in drug dependence]. (2003) (0)
Impact of perinatal immune activation on neuropsychological development (2010) (0)
The mice with exonic Reln deletion show cognitive dysfunction but not attention impairment in the touchscreen operant tasks (2021) (0)
C5a is a target to prevent peritoneal tissue damage in acute peritoneal injury in rats (2012) (0)
Tissue Plasminogen Activator (t-PA) Is Involved in Morphine-Induced Rewarding Effects (2004) (0)
[Pharmacological studies on metolazone (author's transl)]. (1977) (0)
Retraction. Effects of open-air temperature on air temperature inside biological safety cabinet. (2011) (0)
[Pro- and anti-addictive factors related to drug addiction]. (2005) (0)
PM373. Behavioral and neurochemical abnormalities in heterozygous Reelin Orleans mutant mouse model of schizophrenia (2016) (0)
The role of Npas4 in neurite outgrowth and phosphorylated synapsin I expression in Neuro2a cells and primary cultured hippocampal neurons (2010) (0)
PHARMACODYNAMIC CHARACTARISTICS OF RENAL TRANSPLANT RESIPIENTS: 944 (2008) (0)
Ovariectomy potentiates β-amyloid-induced working memory deficits in rats (1999) (0)
[A fundamental study on a bioassay for the antiphlogistic effect of topically applied antiinflammatory agents (author's transl)]. (1979) (0)
PS134. A strategy for treating in deficits of social behaviors induced by exposure to social defeat stress as juveniles (2016) (0)
Documenting the value of a pharmacist-managed anticoagulation classroom (2008) (0)
The role of prostaglandin E2 in environmental factors of psychiatric disorders (2020) (0)
[Functional analysis of stress-responsible transcription factor Npas4 in stress-induced brain dysfunction]. (2012) (0)
Ovariectomy causes hippocampal neuronal loss and cognitive dysfunction and restored by Ginkgo biloba extract EGb761 in rats (2009) (0)
Postsynaptic enhancement by motilin of muscarinic receptor cation currents in duodenal smooth muscle. (1998) (0)
P3.01-34 Short Hydration Regimen with a Modified Dose of Magnesium Supplementation for Lung Cancer Patients Receiving Cisplatin-Based Chemotherapy (2018) (0)
[Physiological centers of decision-making: manipulation of neural activity in insular cortex by AAV]. (2019) (0)
Effects of open-air temperature on air temperature inside biological safety cabinet. (2011) (0)
[Pharmacological studies on alprazolam, and its main metabolites, alpha-OH-alprazolam and HB compound (author's transl)]. (1980) (0)
Involvement of glutamate receptors in the impairment of social behaviors induced by social defeat stress exposure as juveniles (2019) (0)
Acetylsalicylic acid maltol ester attenuates methamphetamine induced neurotoxicity in mice involvement of antiperoxidative effects (2002) (0)
PM376. Mountain-cultivated ginseng attenuates phencyclidine (PCP)-induced schizophrenia-like psychosis in mice (2016) (0)
Effects of Nobiletin in Animal Models of Cognitive Impairment: Current Insights and Future Perspectives (2017) (0)
Improvement in drug compliance by medical consultation at a Pharmacist Outpatients' Clinic (Part 1) (2003) (0)
NITRIC OXIDE PRODUCTION IN VIVO IN THE BRAIN FOLLOWING A DIRECT INTRAHIPPOCAMPAL INJECTION OF LIPOPOLYSACCHARIDE IN RATS (1997) (0)
JSNP excellent presentation award for CINP2016: A strategy for treating in deficits of social behaviors induced by exposure to social defeat stress as juveniles (2017) (0)
Effects of naftopidil on dorsal root evoked excitatory synaptic transmissions in substantia gelatinosa neurons in vitro (2022) (0)
1903 Behavioral and neurochemical evidences that w-conotoxin gvia inhibits the striatal dopamine release in vivo (1993) (0)
The effect of anthocyanin-rich blackcurrant extracts on behavioral abnormalities in SAMP8 mice (2020) (0)
P-9-19: Phencyclidine-induced schizophrenia negative symptom-like behavior in mice: Comparative study of risperidone andhaloperidol (1996) (0)
S9-2 Anti-addictive and pro-addictive substances commonly involved in methamphetamine and morphine dependence(SYMPOSIUM 9: MOLECULAR MECHANISMS OF DRUG DEPENDENCE)(Proceedings of the 31st Annual Meeting) (2004) (0)
Erratum to: A retrospective study to identify risk factors for somnolence and dizziness in patients treated with pregabalin (2016) (0)
Preparation of Alzheimers Animal Model and Brain Dysfunction Induced by Continuous $\beta$-Amyloid Protein Infusion (2001) (0)
Aberrant DNA Methylation Is Associated With Poor Outcomes In Juvenile Myelomonocytic Leukemia (2013) (0)
Effect of Dietary Fiber onMorphine-inducedConstipation in Rats JSem (2017) (0)
Contents Vol. 85, 2013 (2013) (0)
The effect of polyI:C treatment on endophenotypes in dominant-negative DISC1 transgenic mice (2009) (0)
Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons (2020) (0)
Beneficial treatment of nicotine in methamphetamine (METH)-induced impairment of sensorimotor gating (2009) (0)
PKA/CREB/c-fos pathway in the hippocampus is involved in spatial memory fomation in rats (2001) (0)
Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice (2018) (0)
Neuronal mechanism of nociceptin-induced modulation of learning and memory (2000) (0)
[Preparation of standard protocol for cancer pain control and evaluation of its clinical effectiveness]. (2010) (0)
The perinatal mice administered prostaglandin E 2 develop psychobehavioral and neuronal impairments in adults (2018) (0)
[Candidate genes or compounds for therapeutic tools against methamphetamine and/or morphine-induced dependence]. (2003) (0)
Evaluation of cognitive behaviors in young offspring of C57BL/6J mice after gestational nicotine exposure during different time-windows (2013) (0)
Research on Polypharmacy in Patients with Oxycodone Introduction for Cancer Pain (2019) (0)
Participation of opiate systems in footshock-induced analgesia and motor suppression in mice (1983) (0)
Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in medium spiny neurons (2018) (0)
Acute methamphetamine administration impairs cognitive function in a mouse model of schizophrenia with both of CNV and SNV in ARHGAP10 gene that confer high risk of schizophrenia with severe clinical symptoms. (2019) (0)
Memory Impairment in Rats Induced by an Active Fragment of Nerve Growth Factor Antibody (1990) (0)
The cognitive function of the mice with an exonic deletion of RELN is impaired in touchscreen-based visual discrimination task (2020) (0)
Examination of the Use Survey and the Usefulness of Tramadol in Cancer Pain Patients (2016) (0)
Dopaminergic inhibition involved in the alpha-naphthoxyacetic acid-induced jumping behavior in mice. (1980) (0)
Association Study between Genes Related to Pharmacokinetics andPharmacodynamics of Oxycodone and Response to Drug Treatment: AGenetic Cohort Study (2019) (0)
Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia (2018) (0)
PHARMACODYNAMIC EVALUATION OF CYCLOSPORINE IN B-CELL: 906 (2010) (0)
[Behavioral pharmacology and psychopharmacology]. (2011) (0)
Transcriptional regulation of neuronal PAS domain 4 (NPAS4) by stress (2011) (0)
[Usage of gastric antisecretory drugs in palliative care of lung cancer patients]. (2012) (0)
Stress-induced brain dysfunction and functional analysis of stress-responsible transcription factor Npas4 (2012) (0)
Study on Adhesive Characteristics of Formulation Modified Esflurbiprofen Mentha Oil Formulation (SFP tape), a Transdermal Analgesic/Anti-inflammatory Tape (2020) (0)
Analysis of a mouse model of the human 22q11.2 microdeletion syndrome with 3 Mb deletion (2017) (0)
Characterization of learning and memory deficits in the mice infected with LP-BM5 (1998) (0)
Cost-effectiveness Analysis of Pegfilgrastim in Patients with Non-Hodgkin Lymphoma for the Primary Prophylaxis of Febrile Neutropenia Associated with CHOP Chemotherapy (2018) (0)
[Dynamics and functional analysis of cytokines/proteinases with drug dependence]. (2008) (0)
Generation and behavioral analysis of PCDH15-deficient model mice (2019) (0)
Roles of orexin neurons in motivated behaviors in rats (2020) (0)
Innate immune activation of astrocytes impairs neurodevelopment via upregulation of follistatin-like 1 and interferon-induced transmembrane protein 3 (2018) (0)
Low TNFAIP3 was normalized with antidepressant in patients with major depressive disorder anxiety- and depressive-like behaviours in adolescent offspring: a rodent model Transcriptomic evidence for dematuration of the mouse frontal cortex and hippocampus by chronic antidepressant treatment (2016) (0)
Comparing incidences of infusion site reactions between brand‐name and generic vinorelbine in patients with non‐small cell lung cancer (2020) (0)
Retrospective Study of Introducing Suvorexant to Long-term Users of Benzodiazepines (2021) (0)
Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells (2016) (0)
Association between the Incidence of Chemotherapy with Cisplatin and Fluorouracil-induced Vomiting and the Body's Water Balance (2015) (0)
22B-10-4 Analysis of morphine dependence mechanism using cyclic AMP responsive element binding protein binding protein (CBP) mutation mice. (1999) (0)
Pharmacist-managed clinics for patient education and counseling in Japan: current status and future perspectives (2015) (0)
[Effects of Renal Function Evaluation with or without Serum Creatinine Adjustment on Cisplatin/Fluorouracil Therapy for Cervical Cancer]. (2019) (0)
Membrane complement regulators may protect against encapsular peritoneal sclerosis (EPS) in a chronic proliferative peritoneal inflammation model of zymosan peritonitis in the rat (2010) (0)
406 Measurement of nitrite and nitrate in the cerebellum of awake rats by using in vivo brain microdialysis (1996) (0)
Phenotypic analysis of DISC1 knockout mice (2010) (0)
Non-physiological osmolarity and pH in peritoneal dialysis fluid impair complement regulation in rat peritoneal mesothelial cells (2011) (0)
Fstl1 mediates polyI:C-induced neuronal impairment. (2019) (0)
Phencyclidine increases the extracellular acetylcholine level in the rat parietal cortex partly through sigma receptors (1995) (0)
[Role of tissue plasminogen activator in the rewarding effect of morphine]. (2006) (0)
Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex (2018) (0)
A survey of antipsychotic polypharmacy in outpatients at Nagoya University Hospital (2010) (0)
Survey of chemotherapy-induced nausea and vomiting in patients with urothelial carcinoma. (2021) (0)
CBP Mutant Mice Showed A Reduced Morphine Withdrawal Syndrome And Altered Gene Expressions (1999) (0)
[Molecular basis of brain disruption in neuropsychological diseases]. (2013) (0)
An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference. (2023) (0)
Role of AUTS2 in synaptic formation during the cortical development and the cognitive brain functions. (2017) (0)
P4-227: Role of receptor for advanced glycation endproducts in neuronal amyloid β-peptide membrane transport (2008) (0)
Reward signals downstream of dopamine D1 receptors. (2016) (0)
Contents Vol. 82, 2012 (2012) (0)
Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice (2020) (0)
DOPAMINERGIC INVOLVEMENT IN PHENCYCLIDINE-INDUCED STEREOTYPED BEHAVIOR (1985) (0)
Effectiveness of Inhalation Therapy Support by Pharmacists for Symptoms and Lung Function in Chronic Obstructive Pulmonary Disease Patients (2019) (0)
Japanese Abstract (2020) (0)
Exploring biomarkers and therapeutic targets by genome copy number variation (2019) (0)
Microinjection of Reelin into the medial prefrontal cortex improves MK801-induced memory impairment (2018) (0)
[Behavioral analysis for spatial working memory in rats with a delayed spatial win-shift task in a radial arm maze]. (2007) (0)
OCCURRENCE OF YAWNING AND DECREASE OF PROLACTIN LEVELS VIA STIMULATION OF DOPAMINE D2‐RECEPTORS AFTER ADMINISTRATION OF TALIPEXOLE AND SND 919 IN RATS (1992) (0)
1654. Evaluation of a rapid detection method of clarithromycin resistance genes in Mycobacterium avium using the Amplification Refractory Mutation System-Loop-Mediated Isothermal Amplification method (2020) (0)
Prenatal nicotine exposure impairs the proliferation of neuronal progenitors, leading to fewer gluta- matergic neurons in the medial prefrontal cortex (2016) (0)
[Effect of Ca(2+)-channel antagonists on the corticoidogenesis in primary cultured bovine adrenocortical cells]. (1992) (0)
Usefulness of Peripheral Blood Circulating DNAs As an Alternative to DNA From Bone Marrow Cells to Detect CpG Global Methylation Status and Genetic Mutations in Patients with Myelodysplastic Syndromes (2012) (0)
Association between peripheral cytokine levels and cognitive abilities in children with autism spectrum disorder Resveratrol Suppresses Neuroinflammation in the Experimental Paradigm of Autism Spectrum Disorders (2016) (0)
P.3.d.006 Effects of postnatal intermittent hypoxia on prepulse inhibition and locomotor activity in rats (2009) (0)
Up-regulation of cAMP, but not voltage-sensitive calcium ion channels is involved in the inhibitory effects of nefiracetam on methamphetamine-induced discriminative responses (2003) (0)
Development of the Administration Route of Morphine Hydrochloride Tablets by Simple Suspension Method (2014) (0)
Altered emotional behavior and dopaminergic functions of reelin orleans mice (2014) (0)
Exposure to 1-bromopropane decreases neuron proliferation in adult rat dentate gyrus (2012) (0)
P1-5-4ASSOCIATION OF ABCG2 POLYMORPHISM WITH PLASMA CONCENTRATIONS OF AXITINIB IN PATIENTS WITH RENAL CELL CARCINOMA (2014) (0)
[Dopamine antagonists and their mechanism of action]. (1984) (0)
Role of IFITM3 in brain dysfunction induced by perinatal immune activation (2011) (0)
Role of IFITM3 in polyI: C-induced neuronal impairments (2018) (0)
Role of protein kinase in the substance P-induced inhibition of the GABA response in neurons of the bullfrog dorsal root ganglia. (1996) (0)

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