Klaas de Groot
Dutch bioengineer
Klaas de Groot's AcademicInfluence.com Rankings

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Engineering
Klaas de Groot's Degrees
- Bachelors Biomedical Engineering Delft University of Technology
- Masters Bioengineering Eindhoven University of Technology
- PhD Biomedical Engineering University of Twente
Why Is Klaas de Groot Influential?
(Suggest an Edit or Addition)According to Wikipedia, Klaas de Groot is Emeritus Professor at the Tissue Engineering Group at the University of Twente. In the past he also worked as a visiting scientist at the UCLA bone research laboratory. His work has focused on the research and development of bioceramics that resemble the composition of bone. He has developed two types of bioceramic, namely bulk ceramics for mechanically unloaded bone fillers, and coatings for improving the bone bonding of strong, but less biocompatible, metallic orthopedic and dental implants. His group also studied the incorporation of drugs and growth factors such as Bone Morphogenetic Proteins into such ceramics and coatings, as well as the use of calciumphosphate particles for plastic surgery, i.e. filling and augmenting soft and hard tissues for cosmetic reasons
Klaas de Groot's Published Works
Published Works
- Biomimetic Hydroxyapatite Coating on Metal Implants (2004) (475)
- Bioceramics of Calcium Phosphate (2017) (399)
- Bonelike Hydroxyapatite Induction by a Gel‐Derived Titania on a Titanium Substrate (1994) (325)
- Influence of ionic strength and carbonate on the Ca-P coating formation from SBF×5 solution (2002) (259)
- Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions (2008) (254)
- Thin Calcium Phosphate Coatings for Medical Implants (2009) (225)
- High temperature characteristics of synthetic hydroxyapatite (1993) (213)
- Tissue Engineering of Bone (1997) (206)
- Evaluation of biomaterials (1980) (190)
- Long-term in vivo study of plasma-sprayed coatings on titanium alloys of tetracalcium phosphate, hydroxyapatite and α-tricalcium phosphate (1994) (154)
- Clinical applications of calcium phosphate biomaterials: A review (1993) (113)
- Morphology and composition of nanograde calcium phosphate needle-like crystals formed by simple hydrothermal treatment (1994) (111)
- Preparation and characterization of nanograde osteoapatite-like rod crystals (1994) (104)
- Calcium phosphate cement: in vitro and in vivo studies of the α-tricalcium phosphate-dicalcium phosphate dibasic-tetracalcium phosphate monoxide system (1995) (96)
- Evaluation of hydroxylapatite/poly(l-lactide) composites: physico-chemical properties (1993) (92)
- Studies on the thermal spraying of apatite bioceramics (1992) (89)
- Effect of Porosity and Physicochemical Properties on the Stability, Resorption, and Strength of Calcium Phosphate Ceramics (1988) (84)
- Preparation and properties of sintered hydroxylapatite (1978) (77)
- Shape change and phase transition of needle-like non-stoichiometric apatite crystals (1994) (76)
- Bioactive Ca10(PO4)6(OH)2−TiO2 composite coating prepared by sol-gel process (1996) (76)
- Hydrolysis and phase transition of alpha-tricalcium phosphate (1997) (73)
- Osteoinductive Implants: The Mise-en-scène for Drug-Bearing Biomimetic Coatings (2004) (68)
- Novel Method to Manufacture Porous Hydroxyapatite by Dual‐Phase Mixing (2003) (64)
- Medical applications of calciumphosphate bioceramics (1991) (55)
- In vitro biocompatibility testing of polylactides Part I Proliferation of different cell types (1992) (54)
- Apatite crystallization from metastable calcium phosphate solution on sol-gel-prepared silica (1994) (53)
- Better bioactive ceramics through sol-gel process (1994) (51)
- Bone healing in porous implants: a histological and histometrical comparative study on sheep (2000) (45)
- Critical factors in the design of growth factor releasing scaffolds for cartilage tissue engineering (2008) (45)
- Evaluation of polylactide monomers in an in vitro biocompatibility assay (1994) (40)
- Carriers that concentrate native bone morphogenetic protein in vivo. (1998) (37)
- STABILITY OF CALCIUM PHOSPHATE CERAMICS AND PLASMA SPRAYED COATINGS (1993) (37)
- Porous Ti6Al4V scaffolds directly fabricated by 3D fibre deposition technique: Effect of nozzle diameter (2005) (37)
- Transmucosal implants of dense hydroxylapatite (1983) (36)
- The stability of hydroxyapatite in an optimized bioactive glass matrix at sintering temperatures (1991) (36)
- Cancellous bone from porous T{i}6Al4V by multiple coating technique (2006) (33)
- Calcium phosphate coatings (2008) (33)
- Calcium Phosphate Bioceramics (1984) (32)
- Significance of the Porosity and Physical Chemistry of Calcium Phosphate Ceramics (1988) (27)
- Thermal Bulk Polymerization of Cholesteryl Acrylate (1971) (27)
- Biomimetic Calcium Phosphate Coatings on Ti6Al4V: A Crystal Growth Study of Octacalcium Phosphate and (1999) (26)
- Development of injectable antitumor microspheres based on polyphosphazene (1991) (26)
- Bimolecular Ionization of the Triplet State of Aromatic Hydrocarbons in Solution (1968) (26)
- Crystal growth of calcium phosphate on chemically treated titanium (1998) (25)
- In vitro calcification of orthopaedic implant materials (1995) (24)
- Analysis of the Bony Interface with Various Types of Hydroxyapatite In Vitro (1993) (24)
- Calcium Phosphate Biomaterials: An Overview (2004) (23)
- Preparation and characterization of crosslinked PMMA latex particles stabilized by grafted copolymer (1997) (23)
- Influence of Crystal Structure on the Establishment of the Bone-Calcium Phosphate Interface In Vitro (1993) (23)
- Fast Formation of Biomimetic Ca-P Coatings on Ti6Al4V (1999) (22)
- In vitro biocompatibility testing of polylactides (1993) (20)
- Wound-healing phenomena around percutaneous devices implanted in rabbits (1990) (19)
- Development of implantable antitumor devices based on polyphosphazenes (1988) (18)
- Bulk polymerization of cholesteryl acrylate (1970) (18)
- Biomimetic mineral coatings in dental and orthopaedic implantology (2009) (18)
- Bioceramics for Maxillofacial Applications (1992) (17)
- Development of implantable antitumor devices based on polyphosphazenes, II (1991) (16)
- Reformed bamboo/glass fabric/aluminium composite as an ecomaterial (1998) (15)
- Osteoinductive biomimetic calcium-phosphate coatings and their potential use as tissue-engineering scaffolds (2000) (15)
- Fluorapatite-coated implants in experimental arthritis: the response of rabbit trabecular bone (1994) (14)
- Physical and chemical characteristics of Plasma-Sprayed and Biomimetic Apatite Coating (1999) (13)
- Biomimetic coating of bioactives ceramic on bamboo for biomedical applications (1996) (13)
- Biomimetic Coatings on Orthopedic Implants: a Review (1999) (13)
- Degradation of bioceramics (2008) (12)
- Isolation of α-crystallin by means of continuous flow electrophoresis in a liquid film (1970) (11)
- Ultrastructure of the Mineralized Tissue/Calcium Phosphate Interface in Vitro (1991) (10)
- Ceramics of Calcium Phosphates: Preparation and Properties (2018) (10)
- Bonelike Hydroxyapatite Induction by a Gel-Derived Titania on a Titanium Substrate. (2010) (9)
- Hydroxylapatite as coating for implants (1987) (9)
- Application of Porous Bioceramics in Surgery (1993) (7)
- The molecular weight of the subunits of α-crystallin (1970) (7)
- Synthesis and viscosity behavior of poly(γ‐p‐biphenylmethyl‐L‐glutamate) in benzene/dichloroacetic acid mixtures, a comparison with poly(γ‐benzyl‐L‐glutamate) (1974) (7)
- Local residual ridge augmentation with solid hydroxyapatite blocks: Part II—Correction of local resorption defects in 50 patients (1993) (6)
- Liquid crystalline acrylates and their polymers (1972) (6)
- Preparation of High‐Strength Calcium Phosphate Glass‐Ceramics by Unidirectional Crystallization (2006) (5)
- Patent literature as a source of information for research and development: an investigation on calcium phosphate-containing biomaterials, Part I. (1989) (5)
- Study of the Bone-Biomaterial Interface Reactions in an in Vitro Bone Forming System: A Preliminary Report (1991) (5)
- Preliminary ageing study of bioactive glass in a cell culture model (1995) (5)
- Element-induced thermal decomposition of apatite in plasma sprayed coatings on Ti6Al4V substrates (1996) (5)
- A Calibrated Method for Crystallinity Determination of Hydroxylapatite Coatings (1994) (4)
- Local residual ridge augmentation with solid hydroxyapatite blocks: Part I--An animal experiment. (1993) (4)
- Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic (2008) (3)
- Preferential absorption of (binary) solvents by p‐hydroxyethyl methacrylate gels (1978) (3)
- Bone Apposition on Apatite Coatings Inhibited by Large Gaps (1994) (3)
- BIODEGRADATION OF CALCIUMPHOSPHATE CERAMICS-ULTRASTRUCTURAL GEOMETRY AND DISSOLUBILITY OF DIFFERENT CALCIUMPHOSPHATE CERAMICS. (1984) (3)
- Helix to coil transition in poly(γ-benzyl-L-glutamate) (1971) (3)
- Biomimetic Hydroxyapatite Coatings (2004) (2)
- DETERMINATION OF LONG RANGE ORDER IN Ni3Fe USING THE MOSSBAUER EFFECT TECHNIQUE (1974) (2)
- Medical use of calcium phosphate ceramics (2018) (2)
- New Biomimetic Coating Technologies and Incorporation of Bioactive Agents and Proteins (2004) (2)
- Yield of Free Carriers from Triplet–Triplet Collisions in Fluid Media (1968) (2)
- The molecular weight of the polypeptide chains of α-crystallin (1970) (2)
- Surface Chemistry of Sintered Hydroxyapatite: On Possible Relations with Biodegradation and Slow Crack Propagation (1984) (1)
- Hydroxyapatite/Collagen Scaffolds (2005) (1)
- Calciumphosphate Ceramics: Biomaterials for Middle Ear Implants (1984) (1)
- New Biomimetic HA coatings (1996) (1)
- Canine implantation of HA coated implants (1995) (1)
- Cost-effectiveness of fondaparinux (Arixtra®) compared with enoxaparin as prophylaxis against venous thromboembolism following major orthopedic surgery (2003) (1)
- Mucosal Survival on Porous Titanium (2009) (0)
- 486 Stability of cyclically loaded calcium phosphate coatings : (2018) (0)
- Better growth and differentiation of isolated rat osteoblasts cultured upon Bioglass compared with several other glass substrates (1992) (0)
- Controlled proteins and Ca2 release from biomimietic calcium phosphate coatings on Ti6A14V implants (2001) (0)
- The future in bioactive coatings (1995) (0)
- In vitro study of MC3T3-E1 cells on porous Ti6Al4V scaffolds fabricated using a 3D fiber deposition technique (2005) (0)
- Abstracts of papers Biopharmaceutical meeting (2005) (0)
- Manipulating Bone Formation in Calcium Phosphates with Macrostructures (2008) (0)
- Implant stiffness-dependent bone and Interface reactions : P (2017) (0)
- Inflammatory activity of calcium phosphates (1989) (0)
- Effect of in vitro conditions on the release kinetics and stability of calcitonin-containing poly(ether ester) matrices (2003) (0)
- Immunological Aspects of Contact Hypersensitivity to Nickel and Chromium in Dental Alloys (1988) (0)
- Ceramic foam body (2000) (0)
- Scaffolds, Hydroxyapatite–Collagen (2015) (0)
- The link between morphology and ecology in the Long Term Vision for the Schelde Estuary A conceptual framework and preliminary results (2000) (0)
- Photoionization of aromatic hydrocarbons in liquid solutions (1968) (0)
- Function and composition of pancreatic islet cell implants in omentum of type 1 diabetes patients (2022) (0)
- New biomimetic ceramics for bone replacement (1999) (0)
- Quantitative evaluation/comparison of the osteoinductivity of BMP-2 by 4 different delivery modes in a rat ectopic model (2005) (0)
- The in vitro formation of a calcified extracellular matrix on biomaterials by rat bone marrow cells (1992) (0)
- Differences in Behaviour of Cultured Fetal Rat Osteoblasts Upon Bioglass & Nonreactive Glasses (1992) (0)
- Procede de formation d'un revetement en matiere bioactive sur des implants (1994) (0)
- A way to improve understanding of the physiological response of tissue to implant bioceramics: the thermodynamics of irreversible processes (1991) (0)
- Foraiation and characteristics of the apatite layer on plasma-sprayed hydroxyapatite coatings in simulated body fluid (2017) (0)
- Ceramic material for osteoinduction containing micropores on the Öberfläche of macropores (1999) (0)
- CONTROLLED PROTEINS AND Ca RELEASE FROM BIOMIMETIC CALCIUM PHOSPHATE COATINGS ON Ti 6 Al 4 V IMPLANTS (2016) (0)
- Abstracts of papers biopharmaceutical meeting (2005) (0)
- Implantant of ceramic material (1982) (0)
- UvA-DARE ( Digital Academic Repository ) A review paper on biomimetic calcium phosphate coatings (2015) (0)
- Improve Bone Forming Ability of Calcium Phosphates with Zinc Chloride (ZnCl2) (2008) (0)
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