Konstantinos Drosatos
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Konstantinos Drosatoscomputer-science Degrees
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Computer Science
Why Is Konstantinos Drosatos Influential?
(Suggest an Edit or Addition)According to Wikipedia, Konstantinos Drosatos , born in Athens, Greece, is a Greek-American molecular biologist, who is the Ohio Eminent Scholar and Professor of Pharmacology and Systems Physiology at the University of Cincinnati College of Medicine in Cincinnati, Ohio, U.S. His parents were Georgios Drosatos and Sofia Drosatou; his family originates in Partheni, Euboea, Greece.
Konstantinos Drosatos's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism[S] (2010) (274)
- Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction (2013) (239)
- Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance, and Normalizes Cardiac Metabolism in Patients With Advanced Heart Failure (2012) (226)
- Lipid Use and Misuse by the Heart. (2016) (191)
- Cardiac Lipotoxicity: Molecular Pathways and Therapeutic Implications (2013) (155)
- Pathophysiology of Sepsis-Related Cardiac Dysfunction: Driven by Inflammation, Energy Mismanagement, or Both? (2015) (149)
- Endothelial cell CD36 optimizes tissue fatty acid uptake (2018) (122)
- Peroxisome Proliferator–Activated Receptor-&ggr; Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice (2013) (120)
- MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation (2018) (86)
- Inhibition of c-Jun-N-terminal Kinase Increases Cardiac Peroxisome Proliferator-activated Receptor α Expression and Fatty Acid Oxidation and Prevents Lipopolysaccharide-induced Heart Dysfunction* (2011) (85)
- Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function. (2016) (79)
- Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity. (2014) (74)
- Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function. (2017) (73)
- Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation. (2011) (68)
- Increased de novo ceramide synthesis and accumulation in failing myocardium. (2017) (67)
- Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid‐Induced Triglyceride Formation Prevents It (2014) (67)
- Krüppel-Like Factors (2018) (60)
- Human Aldose Reductase Expression Accelerates Atherosclerosis in Diabetic Apolipoprotein E−/− Mice (2011) (54)
- Adipose-specific Lipoprotein Lipase Deficiency More Profoundly Affects Brown than White Fat Biology* (2013) (50)
- GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels. (2015) (49)
- PPARs: Protectors or Opponents of Myocardial Function? (2015) (41)
- Increased de novo ceramide synthesis and accumulation in failing myocardium. (2017) (38)
- Lipolysis, and Not Hepatic Lipogenesis, Is the Primary Modulator of Triglyceride Levels in Streptozotocin-Induced Diabetic Mice (2015) (37)
- Hyperhomocysteinemia potentiates diabetes-impaired EDHF-induced vascular relaxation: Role of insufficient hydrogen sulfide (2018) (37)
- Dual PPARα/γ activation inhibitsSIRT1-PGC1α axis and causes cardiac dysfunction (2019) (36)
- Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation (2018) (35)
- KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy. (2020) (31)
- Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate but Does Not Change Cardiomyocyte Number in Infant Mice (2019) (29)
- Myocardial Strain and Cardiac Output are Preferable Measurements for Cardiac Dysfunction and Can Predict Mortality in Septic Mice (2019) (28)
- Discrete roles of apoA‐I and apoE in the biogenesis of HDL species: Lessons learned from gene transfer studies in different mouse models (2008) (28)
- Nutriepigenetics and cardiovascular disease (2018) (28)
- Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy. (2019) (27)
- A Dominant Negative Form of the Transcription Factor c-Jun Affects Genes That Have Opposing Effects on Lipid Homeostasis in Mice* (2007) (26)
- Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction. (2019) (21)
- Cardiomyocyte Krüppel-like Factor 5 Promotes De Novo Ceramide Biosynthesis and Contributes to Eccentric Remodeling in Ischemic Cardiomyopathy. (2021) (18)
- Alteration of myocardial GRK2 produces a global metabolic phenotype. (2014) (16)
- Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice (2009) (15)
- DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses—Inflammations and Cancers Can Have High Genomic Risks (2018) (14)
- Amyloid-Beta (1-40) Peptide and Subclinical Cardiovascular Disease. (2018) (13)
- Fatty old hearts: role of cardiac lipotoxicity in age-related cardiomyopathy (2016) (12)
- Metabolic Complications in Cardiac Aging (2021) (12)
- Fish Oil Selectively Improves Heart Function in a Mouse Model of Lipid-induced Cardiomyopathy (2013) (11)
- PKCdelta causes sepsis-induced cardiomyopathy by inducing mitochondrial dysfunction. (2020) (11)
- Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4[S] (2011) (10)
- Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21. (2019) (10)
- Krüppel-like factor (KLF)5: An emerging foe of cardiovascular health. (2021) (10)
- Residues Leu261, Trp264, and Phe265 account for apolipoprotein E-induced dyslipidemia and affect the formation of apolipoprotein E-containing high-density lipoprotein. (2007) (9)
- Cardiac Myocyte KLF 5 Regulates Ppara Expression and Cardiac Function (2015) (9)
- The Glitazars Paradox: Cardiotoxicity of the Metabolically Beneficial Dual PPARα and PPARγ Activation. (2020) (8)
- Savings precede spending: fatty acid utilization relies on triglyceride formation for cardiac energetics. (2014) (8)
- Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through MER Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction (2013) (7)
- Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging (2020) (5)
- Genomic Binding Patterns of Forkhead Box Protein O1 Reveal Its Unique Role in Cardiac Hypertrophy (2020) (5)
- Lipoproteins: A Source of Cardiac Lipids (2014) (3)
- Comprehensive mapping of local and diaspora scientists: a database and analysis of 63951 Greek scientists (2021) (2)
- Crippling and Uncrippling Metabolic Pathways (2)
- Allele-dependent thermodynamic and structural perturbations in ApoE variants associated with the correction of dyslipidemia and formation of spherical ApoE-containing HDL particles. (2013) (2)
- Regulation of ApoA-I Gene Expression and Prospects to Increase Plasma ApoA-I and HDL Levels (2010) (2)
- Dual peroxisome-proliferator-activated-receptor-a / g activation inhibits SIRT 1-PGC 1 a axis and causes cardiac dysfunction (2019) (2)
- Abstract 17347: De novo Ceramide Synthesis is Upregulated by Cardiac Ischemia and is Associated With Cardiomyocyte Apoptosis and Mitochondrial Dysfunction (2015) (1)
- Abstract 19022: Endothelial Cell Specific CD36 Deletion Reduces Uptake of Fatty Acids by the Heart (2014) (1)
- Abstract 10918: High-Throughput Sequencing Analysis of microRNA Profile Dynamics in Patients with Advanced Heart Failure Undergoing Ventricular Assist Device Placement in Comparison to Normal Adult and Fetal Cardiac Expression (2011) (1)
- Abstract 278: PGC1α Activation Corrects Cardiac Dysfunction Caused by Anti-diabetic Dual-PPARα/γ Therapy (2017) (1)
- Abstract 15928: miR-195 Regulates Myocardial Metabolism in Heart Failure via Alternations in SIRT3 Expression and Mitochondrial Protein Acetylation Profile (2017) (1)
- B-type natriuretic peptide is upregulated by c-Jun N-terminal kinase and contributes to septic hypotension (2020) (1)
- Abstract 113: Klf5 and Ppara Expression is Increased at the Early Stage and Reduced at the Late Stage of Myocardial Ischemia/Reperfusion in Mice (2015) (1)
- Greek scientists desperate for a national research foundation (2022) (0)
- Inhibition of Cardiac Glucose Transport Corrects Diabetic Cardiomyopathy Even Without Alleviation of Hyperglycemia (2022) (0)
- Cardiac Myocyte KLF5 Regulates Adiposity via Alteration of Cardiac FGF21 (2017) (0)
- Abstract 17746: Cardiomyocyte-Specific KLF5 Deletion Accelerates Diet-Induced Obesity via Cardiac FGF21 (2017) (0)
- Specificity Proteins (SP) and Krüppel-like Factors (KLF) in Liver Physiology and Pathology (2023) (0)
- Data for "Comprehensive mapping of local and diaspora scientists for evaluation, planning and policy purposes: a database and analysis of 63951 Greek scientists" (2021) (0)
- The role of glucose in cardiac physiology and pathophysiology. (2023) (0)
- Abstract O-1: Klf5 Regulates Cardiac Pparα and Med13 and affects Cardiac Fatty Acid Metabolism And Obesity (2014) (0)
- Generation LWBS: introducing life–work balance in science (2022) (0)
- Abstract 17036: Cardiomyocyte Krüppel-Like Factor 5 Regulates Ceramide Biosynthesis and Promotes Systolic Dysfunction in Ischemic Heart Failure (2020) (0)
- Heart Failure Ventricular Assist Device Implantation Corrects Myocardial Lipotoxicity, Reverses Insulin Resistance, and Normalizes Cardiac Metabolism in Patients With Advanced Heart Failure (2012) (0)
- Hyperglycemia in Mice with Early Diabetes Predisposes for Cardiac Dysfunction (2021) (0)
- Cardiometabolic Diseases (2023) (0)
- Cardiac KLF5 Is Upregulated by FOXO1 and Accounts for Cardiomyopathy in Type 1 Diabetes (2019) (0)
- Abstract GS111: Inhibition Of Cardiac Glucose Transporter 1 Suppresses Early Glucose Dependency And Klf5 Activation And Treats Cardiomyopathy In Diabetes (2022) (0)
- Abstract 548: Cardiomyocyte-KLF5 Expression is Increased by FOXO1 and Accounts for Cardiomyopathy in Type-1 Diabetes (2019) (0)
- Abstract 17827: Klf5 Mediates Glucose-driven Changes ofCcardiac Pparα in Diabetes (2014) (0)
- Abstract 13269: Activation of Ppar{gamma} Increases Energy Production and Prevents Cardiac Dysfunction in Sepsis (2011) (0)
- Abstract 17916: Klf5 is a Transcriptional Regulator of Cardiac Med13 and Affects High Fat Diet-induced Obesity (2014) (0)
- Abstract 16563: FOXO1 Induces Cardiomyocyte-KLF5, Which Drives Oxidative Stress and Diabetic Cardiomyopathy (2020) (0)
- Esrrg participates in the fibrate mediated activation of genes of lipid and lipo-protein metabolism in a human apoA-I transgenic mouse model: A pharmacogenomics approach (2009) (0)
- Schulze et al Cardiac Lipotoxicity 1737 Evidence of Lipotoxicity in the Human Heart (2016) (0)
- Abstract 834: Residues Leu261, Trp264 and Phe265 Account for Apolipoprotein E Induced Dyslipidemia and Affect the Biogenesis of Apolipoprotein E Containing High Density Lipoprotein (2006) (0)
- Abstract: P1123 MICRORNAS 122 AND 370 CONTROL GENES INVOLVED IN LIPID METABOLISM AND HEPATIC TRIGLYCERIDE ACCUMULATION (2009) (0)
- Abstract 210: PPARγ Activation Prevents Cardiac Dysfunction in Sepsis via Stimulation of Energy Production (2012) (0)
- Cardiovascular aging: from cellular and molecular changes to therapeutic interventions (2023) (0)
- Abstract: 1498 THE ROLE OF APOLIPOPROTEIN E IN TRIGLYCERIDE HOMEOSTASIS AND THE BIOGENESIS OF HDL (2009) (0)
- Cardiomyocyte Krüppel‐like Factor 5 Regulates Ceramide Biosynthesis and miR‐30 Suppression in Ischemic Cardiomyopathy and Promotes Systolic Dysfunction (2020) (0)
- Abstract 301: Initial Increase of Klf5 and Ppara Expression After Myocardial Ischemia/Reperfusion in Mice Appears to be Critical for Survival (2016) (0)
- KLF5 mediates glucose-driven changes of cardiac PPARα in diabetes (2018) (0)
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