Kornelia Polyak
#82,055
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Cancer researcher
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Kornelia Polyaklaw Degrees
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#1779
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Kornelia Polyakphilosophy Degrees
Philosophy
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#2371
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Kornelia Polyak's Degrees
- Doctorate Medicine Harvard University
Why Is Kornelia Polyak Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kornelia Polyak is a professor of medicine at Harvard Medical School and an internationally recognized breast cancer expert. Polyak earned her MD from Albert Szent-Gyorgyi Medical University in Szeged, Hungary, and her PhD from Weill Cornell Graduate School of Medical Sciences/Sloan-Kettering Cancer Center in New York City. She then did a fellowship in cancer genetics at Johns Hopkins Oncology Center with Bert Vogelstein and Kenneth Kinzler.
Kornelia Polyak's Published Works
Published Works
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells (2008) (8195)
- Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits (2009) (3183)
- Mesenchymal stem cells within tumour stroma promote breast cancer metastasis (2007) (3008)
- The Genomic Landscapes of Human Breast and Colorectal Cancers (2007) (2549)
- A model for p53-induced apoptosis (1997) (2531)
- Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals (1994) (2268)
- Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. (1998) (2005)
- p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. (1994) (1928)
- Intra-tumour heterogeneity: a looking glass for cancer? (2012) (1681)
- A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 Kip1 -Deficient Mice (1996) (1610)
- Molecular definition of breast tumor heterogeneity. (2007) (1415)
- Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex (1995) (1411)
- Tumor heterogeneity: causes and consequences. (2010) (1365)
- Molecular characterization of the tumor microenvironment in breast cancer. (2004) (1287)
- 14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression (1997) (1160)
- Sequence analysis of mutations and translocations across breast cancer subtypes (2012) (1133)
- Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state (2011) (1095)
- Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. (1995) (1060)
- lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin (1994) (1006)
- Somatic mutations of the mitochondrial genome in human colorectal tumours (1998) (841)
- The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. (2011) (820)
- Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27 Kip1 ) of cyclin-dependent kinase 4 activation (1994) (792)
- Analysis of human transcriptomes (1999) (783)
- Heterogeneity in breast cancer. (2011) (772)
- Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene (2007) (613)
- Co-evolution of tumor cells and their microenvironment. (2009) (597)
- Breast cancer: origins and evolution. (2007) (592)
- 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. (1997) (579)
- Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta. (1993) (565)
- Toward understanding and exploiting tumor heterogeneity (2015) (557)
- Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment. (2019) (538)
- Regulation of in situ to invasive breast carcinoma transition. (2008) (521)
- Contribution of bone marrow–derived endothelial cells to human tumor vasculature (2005) (519)
- Distinct epigenetic changes in the stromal cells of breast cancers (2005) (505)
- Genetic determinants of p53-induced apoptosis and growth arrest. (1996) (502)
- Tumorigenesis: it takes a village (2015) (457)
- A public database for gene expression in human cancers. (1999) (447)
- Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (439)
- Response and resistance to BET bromodomain inhibitors in triple negative breast cancer (2015) (437)
- Breast Tumor Heterogeneity: Cancer Stem Cells or Clonal Evolution? (2007) (429)
- Cellular heterogeneity and molecular evolution in cancer. (2013) (428)
- Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. (2013) (419)
- Ductal carcinoma in situ of the breast. (2004) (398)
- Heterogeneity for Stem Cell–Related Markers According to Tumor Subtype and Histologic Stage in Breast Cancer (2010) (388)
- Roots and stems: stem cells in cancer (2006) (386)
- Oncogene-like induction of cellular invasion from centrosome amplification (2014) (358)
- The microenvironment in breast cancer progression: biology and implications for treatment (2011) (357)
- p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. (1995) (349)
- An anatomy of normal and malignant gene expression (2002) (326)
- Microenvironmental regulation of cancer development. (2008) (325)
- Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. (2010) (324)
- The role of the microenvironment in mammary gland development and cancer. (2010) (310)
- Molecular markers in ductal carcinoma in situ of the breast. (2003) (290)
- Non-cell autonomous tumor-growth driving supports sub-clonal heterogeneity (2014) (282)
- Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance. (2020) (281)
- Classifying the evolutionary and ecological features of neoplasms (2017) (276)
- No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas (2008) (273)
- DNA methylation of RASSF1A, HIN‐1, RAR‐β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma (2003) (269)
- A SAGE (serial analysis of gene expression) view of breast tumor progression. (2001) (250)
- Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. (2014) (243)
- The cancer stem cell hypothesis: in search of definitions, markers, and relevance (2008) (239)
- Cell type-specific DNA methylation patterns in the human breast (2008) (235)
- The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020) (234)
- The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival (2017) (230)
- Moving AHEAD with an international human epigenome project (2008) (202)
- An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ (2009) (202)
- Role of COX-2 in epithelial–stromal cell interactions and progression of ductal carcinoma in situ of the breast (2009) (199)
- Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression. (2006) (197)
- Do Myoepithelial Cells Hold the Key for Breast Tumor Progression? (2005) (188)
- The Origins and Implications of Intratumor Heterogeneity (2010) (185)
- RNA sequencing of cancer reveals novel splicing alterations (2013) (179)
- Genetic and phenotypic diversity in breast tumor metastases. (2014) (175)
- Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome (2014) (169)
- Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues. (1996) (166)
- JARID1B is a luminal lineage-driving oncogene in breast cancer. (2014) (150)
- Very High Frequency of Hypermethylated Genes in Breast Cancer Metastasis to the Bone, Brain, and Lung (2004) (150)
- MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis. (2014) (149)
- Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. (2017) (145)
- Gene discovery using the serial analysis of gene expression technique: implications for cancer research. (2001) (144)
- HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells (2001) (143)
- In situ single cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2+ breast cancer (2015) (138)
- p 27 Kip 1 , a cyclin-Cdk inhibitor , links transforming growth factor-13 and contact inhibition to cell cycle arrest (2007) (138)
- PIK3CA mutations in in situ and invasive breast carcinomas. (2010) (137)
- Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. (1996) (136)
- Intratumoral Heterogeneity: More Than Just Mutations. (2019) (135)
- Molecular characterisation of the tumour microenvironment in breast cancer. (2008) (134)
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. (2018) (133)
- PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling (2011) (133)
- Mammalian antiproliferative signals and their targets. (1995) (132)
- BRCA1 haploinsufficiency for replication stress suppression in primary cells (2014) (132)
- Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase. (2009) (125)
- Targeting Akt3 signaling in triple-negative breast cancer. (2014) (125)
- A neural survival factor is a candidate oncogene in breast cancer (2003) (123)
- CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling (1999) (123)
- Cancer stem cells: a model in the making. (2009) (123)
- Evolutionary pathways in BRCA1-associated breast tumors. (2012) (120)
- Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression) (2002) (120)
- The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. (2013) (115)
- Intratumor Heterogeneity in Breast Cancer. (2016) (115)
- Identifying tumor origin using a gene expression-based classification map. (2003) (109)
- Genome-wide functional synergy between amplified and mutated genes in human breast cancer. (2008) (108)
- Psoriasin expression in mammary epithelial cells in vitro and in vivo. (2002) (106)
- Origin of carcinoma associated fibroblasts (2009) (103)
- Estrogen Receptor/Progesterone Receptor-Negative Breast Cancers of Young African-American Women Have a Higher Frequency of Methylation of Multiple Genes than Those of Caucasian Women1 (2004) (99)
- Cellular and molecular targets of estrogen in normal human breast tissue. (2002) (98)
- Epithelial and Stromal Cathepsin K and CXCL14 Expression in Breast Tumor Progression (2008) (98)
- Precancer Atlas to Drive Precision Prevention Trials. (2017) (98)
- Cancer chromosomes in crisis (2004) (97)
- Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer. (2000) (96)
- The challenges posed by cancer heterogeneity (2012) (96)
- Epigenetic Regulation of Cell Type–Specific Expression Patterns in the Human Mammary Epithelium (2011) (95)
- A putative role for psoriasin in breast tumor progression. (2005) (94)
- G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells (2017) (93)
- Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments (2019) (91)
- Negative regulation of cell growth by TGFβ (1996) (90)
- Cyclins, Cdks, and cyclin kinase inhibitors. (1994) (90)
- Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes. (2016) (88)
- p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. (2000) (88)
- Sorting out the FACS: a devil in the details. (2014) (80)
- Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. (2013) (80)
- Pregnancy and breast cancer: the other side of the coin. (2006) (80)
- Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer (2018) (78)
- On the birth of breast cancer. (2001) (78)
- Somatic mutations in the notch, NF‐KB, PIK3CA, and hedgehog pathways in human breast cancers (2012) (77)
- Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers. (2017) (76)
- PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival (2010) (75)
- Erratum: Genetic determinants of p53-induced apoptosis and growth arrest ((Genes and Development (1996) 10 (1945-1952)) (1996) (74)
- Stem cells in the human breast. (2010) (72)
- HOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance. (2015) (70)
- Clonal mutations in the cancer-associated fibroblasts: the case against genetic coevolution. (2009) (69)
- Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. (2020) (67)
- Intratumor heterogeneity defines treatment‐resistant HER2+ breast tumors (2018) (66)
- Tumor Heterogeneity Confounds and Illuminates: A case for Darwinian tumor evolution (2014) (66)
- HIN-1, an Inhibitor of Cell Growth, Invasion, and AKT Activation (2005) (66)
- Molecular markers for the diagnosis and management of ductal carcinoma in situ. (2010) (65)
- Identification of CD44v6+/CD24− breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies (2009) (63)
- The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium (2011) (62)
- Altered antisense-to-sense transcript ratios in breast cancer (2010) (61)
- Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer. (2015) (61)
- CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer. (2015) (61)
- Cancer Cell Phenotypes, in Fifty Shades of Grey (2013) (60)
- CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. (1999) (58)
- Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations (2010) (56)
- HER2 heterogeneity as a predictor of response to neoadjuvant T-DM1 plus pertuzumab: Results from a prospective clinical trial. (2019) (56)
- p27KIP1, an inhibitor of cyclin-dependent kinases. (1995) (53)
- Epigenetic patterns of embryonic and adult stem cells (2009) (53)
- Methylation‐specific digital karyotyping of HPV16E6E7‐expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis (2013) (53)
- BET Bromodomain Proteins as Cancer Therapeutic Targets. (2016) (53)
- Combining miR-10b-Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer. (2015) (52)
- Histone Demethylase Jumonji AT-rich Interactive Domain 1B (JARID1B) Controls Mammary Gland Development by Regulating Key Developmental and Lineage Specification Genes* (2014) (50)
- Immune Escape during Breast Tumor Progression (2020) (50)
- Serial Analysis of Gene Expression (SAGE) (2003) (50)
- Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. (2004) (50)
- SnapShot: breast cancer. (2012) (50)
- BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. (2016) (49)
- Is Breast Tumor Progression Really Linear? (2008) (46)
- Gene expression profiling of human breast tissue samples using SAGE-Seq. (2010) (46)
- Detection of psoriasin/S100A7 in the sera of patients with psoriasis (2009) (45)
- Impact of HER2 heterogeneity on treatment response of early-stage HER2-positive breast cancer: phase II neoadjuvant clinical trial of T-DM1 combined with pertuzumab. (2021) (45)
- Targeting the missing links for cancer therapy (2011) (45)
- S100A7-Downregulation Inhibits Epidermal Growth Factor-Induced Signaling in Breast Cancer Cells and Blocks Osteoclast Formation (2008) (44)
- Myoepithelial cell‐specific expression of stefin A as a suppressor of early breast cancer invasion (2017) (43)
- Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells (2015) (42)
- Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues (2002) (42)
- The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women. (2016) (40)
- Identifying key questions in the ecology and evolution of cancer (2021) (38)
- Tracking tumor resistance using 'liquid biopsies' (2013) (37)
- Cancer: Clonal cooperation (2014) (36)
- Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer (2016) (36)
- Metastasis as a systemic disease: molecular insights and clinical implications. (2019) (36)
- Cyclooxygenase-2 expression during immortalization and breast cancer progression. (2008) (36)
- EN1 is a transcriptional dependency in triple-negative breast cancer associated with brain metastasis. (2019) (35)
- Expression of estrogen receptor, progesterone receptor, and Ki67 in normal breast tissue in relation to subsequent risk of breast cancer (2016) (34)
- Breast Cancer Stem Cells: A Case of Mistaken Identity? (2007) (33)
- Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors. (2003) (33)
- Negative regulation of cell growth by TGF beta. (1996) (33)
- SAGE and related approaches for cancer target identification. (2006) (32)
- TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer (2018) (32)
- Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ (2019) (31)
- Dissecting the mammary gland one cell at a time (2018) (30)
- Methylation-specific digital karyotyping (2006) (29)
- Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer (2020) (29)
- Breast-cancer stromal cells with TP53 mutations. (2008) (28)
- Molecular alterations in ductal carcinoma in situ of the breast (2002) (27)
- Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9 (2008) (26)
- On using functional genetics to understand breast cancer biology. (2012) (25)
- Serial analysis of gene expression (2006) (23)
- A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. (2012) (23)
- Epidemiology, Biology, Treatment, and Prevention of Ductal Carcinoma In Situ (DCIS) (2018) (23)
- Clonal evolution in cancer: a tale of twisted twines. (2015) (23)
- Progress in breast cancer research (2012) (23)
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. (2019) (22)
- The Expression of Psoriasin (S100A7) and CD24 Is Linked and Related to the Differentiation of Mammary Epithelial Cells (2012) (22)
- MITI minimum information guidelines for highly multiplexed tissue images (2021) (22)
- Breast tumor heterogeneity: causes and consequences (2009) (21)
- Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition (2020) (20)
- The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer (2021) (20)
- Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling (2015) (18)
- Less death in the dying (1997) (17)
- Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition. (2020) (17)
- Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System (2020) (14)
- The p27Kip1 tumor suppressor gene: Still a suspect or proven guilty? (2006) (14)
- Scientific Summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) Program 10th Anniversary Conference (2017) (13)
- Tumor Neoantigens: When Too Much of a Good Thing Is Bad. (2019) (13)
- Functional synergies yet distinct modulators affected by genetic alterations in common human cancers. (2011) (13)
- Untangling the web of intratumour heterogeneity (2022) (13)
- A roadmap for the next decade in cancer research (2020) (12)
- Unraveling the complexity of basal-like breast cancer (2011) (12)
- Serial Analysis of Gene Expression (SAGE) (2003) (12)
- Cancer target discovery using SAGE (2003) (11)
- Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress (2022) (11)
- Breast cancer gene discovery (2002) (9)
- EMSY links breast cancer gene 2 to the 'Royal Family' (2004) (8)
- Phase II study of ruxolitinib , a selective JAK 1 / 2 inhibitor , in patients with metastatic triple-negative breast cancer (2018) (8)
- Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk. (2017) (8)
- Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment (2019) (8)
- Deconvoluting complex tissues for expression quantitative trait locus-based analyses (2013) (8)
- Early-Life Body Adiposity and the Breast Tumor Transcriptome. (2020) (7)
- Cyclooxygenase-2 expression during immortalization and breast cancer progression (Cancer Research (2008) 68, (467-475)) (2008) (7)
- Abstract P4-06-01: JAK2/STAT3 activity in inflammatory breast cancer supports the investigation of JAK2 therapeutic targeting (2012) (6)
- The mammary gland as an experimental model : a subject collection from Cold Spring Harbor perspectives in biology (2011) (6)
- Tumor heterogeneity: the Lernaean hydra of oncology? (2014) (6)
- Serial Analysis of Gene Expression (SAGE): Experimental Method and Data Analysis (2007) (6)
- Premenopausal Plasma Osteoprotegerin and Breast Cancer Risk: A Case–Control Analysis Nested within the Nurses' Health Study II (2020) (5)
- Is p53 a Breast Cancer Gene? (2002) (5)
- Going small is the new big (2010) (5)
- Phase II study of ruxolitinib in patients with pStat3+ breast cancer. (2013) (5)
- A confetti trail of tumour evolution (2018) (5)
- Report of the First International Symposium on NUT Carcinoma. (2022) (4)
- DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts (2021) (4)
- Voices of biotech (2016) (4)
- A Darwinian perspective on tumor immune evasion (2021) (4)
- Intra-tumor heterogeneity defines treatment-resistant HER2+ breast tumors (2018) (4)
- HIN-1, an inhibitor of cell growth, invasion, and AKT1 activation (2005) (4)
- The Expression of Psoriasin ( S 100 A 7 ) and CD 24 Is Linked and Related to the Differentiation of Mammary Epithelial Cells (2012) (3)
- Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts. (2022) (3)
- Abstract OT3-05-01: TBCRC 039: Phase II study of combination ruxolitinib (INCB018424) with preoperative chemotherapy for triple negative inflammatory breast cancer (2018) (3)
- Abstract P3-05-04: Intra-tumor heterogeneity as a predictor of therapy response in HER2 positive breast cancer (2012) (3)
- The MCF10 Model of Breast Tumor Progression (2021) (3)
- From cause to cure: Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics edited by A.M. Bowcock (1999) (2)
- Abstract B16: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer (2016) (2)
- Breast cancer prevention by short-term inhibition of TGFβ signaling (2022) (2)
- Advances in Brief A SAGE ( Serial Analysis of Gene Expression ) View of Breast Tumor Progression 1 (2001) (2)
- Expression of estrogen receptor , progesterone receptor , and Ki 67 in normal breast tissue in relation to subsequent risk of breast cancer (2017) (2)
- Gene expression profiling in breast cancer: from molecular portraits to personalized medicine (2004) (2)
- Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer (2022) (2)
- Gene Expression: MRNA Transcript Analysis (2003) (2)
- Ductal Carcinoma In situ and the Emergence of Diversity during Breast Cancer Evolution. Commentary (2008) (2)
- Gene Expression: Protein Analysis (2003) (1)
- Abstract B62: Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in DCIS (ductal carcinoma in situ) (2018) (1)
- Adaptation of the sequenom platform to the targeted determination of amplification and allele-specific imbalance in breast cancer (2008) (1)
- A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress (2020) (1)
- On chromatin remodeling in mammary gland differentiation and breast tumorigenesis. (2012) (1)
- Abstract P1-07-02: Mesenchymal stem cell regulated microRNAs converge on the speech gene FOXP2 and regulate breast cancer metastasis (2015) (1)
- [Li-Fraumeni syndrome]. (2019) (1)
- Abstract IA005: Immune escape during breast tumor progression (2021) (1)
- Serial Analysis of Gene Expression (SAGE): Experimental Method and Data Analysis (2007) (1)
- Complex interaction of yeast nuclear proteins with the enhancer/promoter region of SV40 (1991) (1)
- JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States (2022) (1)
- Overview: Gene Structure (2003) (1)
- The role of the tumor microenvironment in breast cancer progression (2005) (1)
- Expression of p 53 and p 21 proteins in various cell lines (2007) (0)
- F-052SYNCHRONOUS MULTIPLE PRIMARY LUNG TUMOURS IN A GENETIC FAMILIAR SYNDROME: HOW TO APPROACH? (2017) (0)
- Knockdown of Dermcidin (DCD) gene expression using RNAi vectors confirms its role as survival and growth factor to breast cancer cells (2007) (0)
- Abstract A023: Sensitivity/resistance mechanisms to KDM5 inhibition in basal breast cancer (2022) (0)
- Extracellular Matrix Biomarkers for Diagnosis, Prognosis, Imaging, and Targeting (2015) (0)
- Abstract PD5-08: The human tumor atlas network (HTAN) breast pre cancer atlas: A multi-omic integrative analysis of ductal carcinoma in situ (DCIS) and correlation with clinical outcomes (2021) (0)
- Breast cancer stem cells (2008) (0)
- Advances in Brief Psoriasin Expression in Mammary Epithelial Cells in Vitro and in Vivo 1 (2001) (0)
- DevelopmentMechanisms Guiding Embryonic Mammary Gland (2012) (0)
- Dissecting the mammary gland one cell at a time (2018) (0)
- Abstract PL05-01: Heterogeneity in DCIS and invasive breast cancers. (2013) (0)
- Abstract S4-02: Principles governing A-to-I RNA editing in breast cancer transcriptome (2015) (0)
- Classification Map Identifying Tumor Origin Using a Gene Expression-based Updated Version (2003) (0)
- Functional relevance of histone demethylase JARID1B (KDM5B) in breast cancer (2015) (0)
- Abstract ES1-1: Non-cell-autonomous drivers of tumor growth and progression (2017) (0)
- Title: Evolutionary pathways in BRCA1-associated breast tumors (2012) (0)
- Abstract P5-21-10: Phase 2 study and correlative analyses of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic, triple-negative breast cancer (2018) (0)
- Breast Cancer Stem Cells: Reply (2007) (0)
- A confetti trail of tumour evolution (2018) (0)
- Abstract PR02: Minor clones can drive polyclonal metastasis by affecting immune microenvironment (2018) (0)
- Pers Pe The Franz Abst Neo geneti numb betwe (2010) (0)
- Breast tumor evolution. (2009) (0)
- Abstract A020: Histone modification by Kmt2c and Kmt2d regulate metastasis in triple-negative breast cancer in vivo (2022) (0)
- Abstract C47: Inference of tumor evolution during chemotherapy by computational modeling and single cell analysis of diversity. (2013) (0)
- Abstract SY02-01: Regulators of in situ to invasive breast carcinoma progression. (2013) (0)
- Global OMICs Profiling and Functional Analysis of CD44+/CD24− Stem-Like Cells in Normal Human Breast Tissue and Breast Cancer (2012) (0)
- In situ to invasive carcinoma transition: escape or release (2003) (0)
- Does the microenvironment regulate breast tumor progression (2006) (0)
- Gene Analysis: DNA (2003) (0)
- Abstract 4248: Methylation specific digital karyotyping of human papillomavirus type 16 E6E7 expressing keratinocytes identifies novel methylation targets in cervical carcinogenesis. (2013) (0)
- In This Issue (2002) (0)
- Tumor and Stem Cell Biology Targeting Akt 3 Signaling in Triple-Negative Breast Cancer (2014) (0)
- Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling (2015) (0)
- Gene D iscovery U sing t he S erial A nalysis o f G ene Expression T echnique: I mplications f or C ancer R esearch (2001) (0)
- Cover Image (2003) (0)
- Abstract ES8-3: Epigenetic heterogeneity in cancer (2015) (0)
- S2-6: ErbB3 Expression Is Required for Maintenance of Normal and Transformed Luminal Breast Epithelial Cells. (2011) (0)
- Abstract A21: Characterization of the immune environment in the in situ to invasive breast carcinoma transition (2018) (0)
- Abstract SY17-01: Intratumor diversity in breast cancer (2012) (0)
- Abstract IA1: Metastasis and diversity in breast cancer (2013) (0)
- Is BreastTumor Progression Really Linear ? 55 Commentary on (2008) (0)
- Abstract P6-14-09: Clinical outcomes of triple negative inflammatory breast cancer treated with contemporary anthracycline and taxane preoperative therapy support further investigation of therapeutic targets (2015) (0)
- Molecular Biology, Genomics, and Proteomics (2003) (0)
- Interview: Advancing translational research in breast cancer (2013) (0)
- Erratum: Methylation-specific digital karyotyping (Nature Protocols (2006) vol. 1 (1621-1636) 10.1038/nprot.2006.278) (2006) (0)
- Abstract BS1-2: Epigenetic targets in breast cancer (2017) (0)
- Abstract GS4-07: The Breast PreCancer Atlas DCIS genomic signatures define biology and correlate with clinical outcomes: An analysis of TBCRC 038 and RAHBT cohorts (2022) (0)
- Tumor Progression and Serial Analysis of Gene Expression Analysis of Breast Combined cDNA Array Comparative Genomic Hybridization (2006) (0)
- Abstract A15: Immune-related changes in breast cancer tumor evolution (2018) (0)
- Abstract PR05: The effect of chemotherapy on HER2+ breast cancer heterogeneity measured by STAR-FISH: Detection of PIK3CA mutation and HER2 amplification at single-cell level in situ (2016) (0)
- Abstract PO-059: The genomic landscape of the in situ to invasive ductal breast carcinoma transition shaped by the immune system (2020) (0)
- Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
- Abstract S5-05: Defective stalled replication fork repair and predisposition to hereditary breast cancer (2015) (0)
- Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer (2018) (0)
- Figure 1.5, [Constructing a genomic library. Genomic...]. (2000) (0)
- Microenvironmental changes in breast tumor progression: genetic or epigenetic?. (2009) (0)
- Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples (2009) (0)
- Title : CLK 2 is an oncogenic kinase and splicing regulator in breast cancer (2014) (0)
- Abstract PL07-01: Molecular profiling of breast cancer in Mexico: Identification of novel therapeutic targets through whole genome sequencing analysis. (2012) (0)
- Abstract PL03-03: The clinical significance of intratumor diversity in breast cancer (2011) (0)
- Abstract B24: Targeting hyaluronan sensitizes breast cancer-associated fibroblasts to lapatinib and overcomes stromal resistance (2016) (0)
- Abstract IA14: Breast tumor evolution: The role of the microenvironment (2018) (0)
- Abstract IA11: Functional and clinical relevance of intratumor heterogeneity in breast cancer (2016) (0)
- Abstract C283: Non-malignant cells from tissues targeted by metastatic breast cancer induce tumor cell resistance to antiestrogens and conventional chemotherapeutic agents. (2013) (0)
- Abstract IA035: DCIS to IDC progression - a key step of immune escape (2022) (0)
- Abstract P1-15-01: Withdrawn (2019) (0)
- Characterization of IBC-1 A Novel Putative Breast Cancer Prognostic and Survival Factor (2004) (0)
- The Hairy Powers of Oncogenes: From Biological Function to Cancer Therapy (2003) (0)
- Abstract IA28: Epigenetic heterogeneity in breast cancer (2016) (0)
- Bacterial Darth Vader: May the force be with you. (2022) (0)
- The Human Tumor Atlas Network (HTAN) Breast PreCancer Atlas: A multi-omic integrative analysis of ductal carcinoma in situ with clinical outcomes (2021) (0)
- Key signaling pathways in breast cancer based on somatic mutation data Frequency of breast cancer subtypes (2012) (0)
- Parity and BRCA1/2-associated breast cancer risk linked to hormone-responsive p27 + luminal epithelial progenitors (2018) (0)
- Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer (2020) (0)
- Identification of a Receptor for Tumor Suppressor HIN-1 (2003) (0)
- Mitochondrial suitable as a tumor marker mutations that affect only one base pair (1999) (0)
- Copy Number Variation in Inflammatory Breast Cancer (2023) (0)
- Amplification and overexpresssion of IKBKE activates NF-kB pathway in breast cancers. (2007) (0)
- Challenges and opportunities for modeling aging and cancer. (2023) (0)
- Cellular and Molecular Targets of Estrogen in Normal Human Breast Tissue 1 (2002) (0)
- ISOLATED p27 PROTEIN AND NUCLEIC ENSURE CODING (1995) (0)
- SAGE-Seq Gene expression profiling of human breast tissue samples using Material (2010) (0)
- Abstract IA26: Tumor evolution: From Darwin’s finches to breast cancer (2020) (0)
- The Human Tumor Atlas Network (HTAN) Breast Precancer Atlas: A Multi-Omic Integrative Analysis of Ductal Carcinoma in situ With Clinical Outcomes (2021) (0)
- Abstract A018: KDM4C histone demethylase connects redox balance to chromatin remodeling via histone H3 tail clipping (2022) (0)
- Abstract SY38-02: Immune-related changes in breast tumor evolution (2016) (0)
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