Koutaro Yokote
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Computer Science
Koutaro Yokote's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Koutaro Yokote's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Once-Weekly Semaglutide in Adults with Overweight or Obesity. (2021) (630)
- Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species (2010) (563)
- Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017 (2018) (421)
- Identification of two juxtamembrane autophosphorylation sites in the PDGF beta‐receptor; involvement in the interaction with Src family tyrosine kinases. (1993) (343)
- Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. (1994) (313)
- Other types of primary hyperlipoproteinemia(hyperlipidemia). Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. (2013) (312)
- Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -2012 version. (2014) (283)
- International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium–Glucose Cotransporter (SGLT) Inhibitors (2019) (183)
- Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. (2012) (181)
- Coronary artery disease. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. (2014) (181)
- Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy. (2003) (180)
- Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders (2013) (174)
- Platelet-derived Growth Factor Activates p38 Mitogen-activated Protein Kinase through a Ras-dependent Pathway That Is Important for Actin Reorganization and Cell Migration* (1999) (170)
- [Pharmacological treatment]. (2007) (166)
- Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells (2016) (163)
- Guidelines for the management of familial hypercholesterolemia. (2012) (163)
- Direct interaction between Shc and the platelet-derived growth factor beta-receptor. (1994) (157)
- Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1. (2015) (148)
- Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes (2014) (147)
- Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)‐β signaling from tumor suppression to oncogenesis in early chronic hepatitis B (2009) (143)
- Diagnostic criteria for dyslipidemia. (2013) (137)
- Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017 (2018) (132)
- NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome (2019) (127)
- Involvement of phosphatidylinositide 3'-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis. (1997) (124)
- Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial. (2016) (123)
- Enhanced expression of osteopontin in human diabetic artery and analysis of its functional role in accelerated atherogenesis. (2000) (119)
- Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration (2015) (107)
- Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial (2018) (106)
- Diagnostic criteria for Werner syndrome based on Japanese nationwide epidemiological survey (2013) (101)
- Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor α modulator, in patients with dyslipidemia: Results from a 24-week, randomized, double blind, active-controlled, phase 3 trial. (2017) (96)
- Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). (2008) (95)
- The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential (2019) (84)
- Efficacy and safety of K-877, a novel selective peroxisome proliferator-activated receptor α modulator (SPPARMα), in combination with statin treatment: Two randomised, double-blind, placebo-controlled clinical trials in patients with dyslipidaemia. (2017) (83)
- Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized Controlled Trial. (2019) (82)
- The roles of transforming growth factor-β and Smad3 signaling in adipocyte differentiation and obesity. (2011) (81)
- Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan (2021) (81)
- Palladium and Platinum Nanoparticles Attenuate Aging-Like Skin Atrophy via Antioxidant Activity in Mice (2014) (80)
- Grb7 is a Downstream Signaling Component of Platelet-derived Growth Factor α- and β-Receptors* (1996) (80)
- Targeted Disruption of TGF-&bgr;–Smad3 Signaling Leads to Enhanced Neointimal Hyperplasia With Diminished Matrix Deposition in Response to Vascular Injury (2005) (71)
- Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial (2018) (68)
- WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects (2017) (66)
- Effects of pitavastatin (LIVALO Tablet) on high density lipoprotein cholesterol (HDL-C) in hypercholesterolemia. (2009) (65)
- Risk of cardiovascular diseases is increased even with mild diabetic retinopathy: the Japan Diabetes Complications Study. (2013) (64)
- Effects of pitavastatin (LIVALO tablet) on the estimated glomerular filtration rate (eGFR) in hypercholesterolemic patients with chronic kidney disease. Sub-analysis of the LIVALO Effectiveness and Safety (LIVES) Study. (2010) (64)
- Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis (2015) (63)
- Enhanced expression of osteopontin by high glucose in cultured rat aortic smooth muscle cells. (1999) (62)
- The obesity-related pathology and Th17 cells (2017) (61)
- Risk factors of atherosclerotic diseases. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerosis cardiovascular diseases for Japanese. (2007) (61)
- Structural Determinants in the Platelet-derived Growth Factor -Receptor Implicated in Modulation of Chemotaxis (*) (1996) (60)
- Diabetic Control and Progression of Retinopathy in Elderly Patients: Five‐Year Follow‐up Study (1994) (60)
- High Glucose-Induced Upregulation of Osteopontin Is Mediated via Rho/Rho Kinase Pathway in Cultured Rat Aortic Smooth Muscle Cells (2004) (59)
- CCN3 Inhibits Neointimal Hyperplasia Through Modulation of Smooth Muscle Cell Growth and Migration (2010) (59)
- The phospholipase-A2 reaction leads to increased monocyte adhesion of endothelial cells via the expression of adhesion molecules. (1993) (58)
- Fibroblast growth factor receptor-1 mediates chemotaxis independently of direct SH2-domain protein binding (1998) (58)
- Hyperglycemia-induced alteration of vascular smooth muscle phenotype. (2002) (57)
- Identification of Tyr-762 in the platelet-derived growth factor α-receptor as the binding site for Crk proteins (1998) (54)
- The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes: an open label pilot study. (2012) (53)
- Pitavastatin: efficacy and safety in intensive lipid lowering (2007) (53)
- Guidance for Pediatric Familial Hypercholesterolemia 2017 (2018) (52)
- Influence of statins on glucose tolerance in patients with type 2 diabetes mellitus: subanalysis of the collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). (2009) (51)
- Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture (2014) (51)
- Wernicke encephalopathy: follow-up study by CT and MR. (1991) (50)
- Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk. (2022) (48)
- Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia (2017) (48)
- New evidence on pitavastatin: efficacy and safety in clinical studies (2010) (47)
- White matter lesions as a feature of cognitive impairment, low vitality and other symptoms of geriatric syndrome in the elderly (2008) (44)
- Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan. (2012) (43)
- Comprehensive risk management for the prevention of cardiovascular disease: executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan -- 2012. (2013) (43)
- Low HDL Cholesterol Is Associated With the Risk of Stroke in Elderly Diabetic Individuals (2009) (41)
- PDGF alpha-receptor mediated cellular responses are not dependent on Src family kinases in endothelial cells. (1998) (41)
- Real-world evidence for the safety of ipragliflozin in elderly Japanese patients with type 2 diabetes mellitus (STELLA-ELDER): final results of a post-marketing surveillance study (2016) (41)
- Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment (2019) (38)
- Intensive Treat-to-Target Statin Therapy in High-Risk Japanese Patients With Hypercholesterolemia and Diabetic Retinopathy: Report of a Randomized Study (2018) (38)
- Smad3 is required for enamel biomineralization. (2003) (37)
- Superoxide Dismutase 1 Loss Disturbs Intracellular Redox Signaling, Resulting in Global Age-Related Pathological Changes (2014) (36)
- METABOLIC IMPROVEMENT AND ABDOMINAL FAT REDISTRIBUTION IN WERNER SYNDROME BY PIOGLITAZONE (2004) (36)
- Dysadipocytokinemia in werner syndrome and its recovery by treatment with pioglitazone. (2004) (36)
- p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells (2018) (35)
- Efficacy and safety of pitavastatin in Japanese patients with hypercholesterolemia: LIVES study and subanalysis (2011) (34)
- Influence of C‐peptide on early glomerular changes in diabetic mice (2006) (34)
- Enhanced Expression of Osteopontin by High Glucose: Involvement of Osteopontin in Diabetic Macroangiopathy a (2000) (33)
- Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction (2017) (32)
- Cultured retinal pericytes stimulate in vitro angiogenesis of endothelial cells through secretion of a fibroblast growth factor-like molecule. (1997) (32)
- Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension (2022) (31)
- Effects of pemafibrate (K-877) on cholesterol efflux capacity and postprandial hyperlipidemia in patients with atherogenic dyslipidemia. (2018) (31)
- Enhanced intra-abdominal visceral fat accumulation in patients with Werner's syndrome (2001) (30)
- NK‐104, a 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitor, reduces osteopontin expression by rat aortic smooth muscle cells (2001) (30)
- Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming (2015) (29)
- Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes (2014) (28)
- Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52‐week data from the PROVIDE study (2019) (28)
- Cushing Syndrome Due to ACTH-Secreting Pheochromocytoma, Aggravated by Glucocorticoid-Driven Positive-Feedback Loop. (2016) (27)
- Elevated Levels of Autoantibodies against ATP2B4 and BMP-1 in Sera of Patients with Atherosclerosis-related Diseases (2015) (27)
- Effects of a novel selective peroxisome proliferator‐activated receptor‐α modulator, pemafibrate, on hepatic and peripheral glucose uptake in patients with hypertriglyceridemia and insulin resistance (2018) (27)
- Continuous glucose monitoring reveals hypoglycemia risk in elderly patients with type 2 diabetes mellitus (2017) (27)
- Matricellular protein CCN3 mitigates abdominal aortic aneurysm. (2016) (27)
- Bone marrow-derived vascular cells in response to injury. (2003) (27)
- Identification of Cerebral Infarction-Specific Antibody Markers from Autoantibodies Detected in Patients with Systemic Lupus Erythematosus (2015) (27)
- Genetic and transcriptional landscape of plasma cells in POEMS syndrome (2019) (27)
- Safety of ipragliflozin in elderly Japanese patients with type 2 diabetes mellitus (STELLA-ELDER): Interim results of a post-marketing surveillance study (2016) (26)
- The role of the hypoxia-inducible factor 1 binding site in the induction of aquaporin-1 mRNA expression by hypoxia. (2011) (25)
- Increased atherogenesis in Otsuka Long-Evans Tokushima fatty rats before the onset of diabetes mellitus: association with overexpression of PDGF beta-receptors in aortic smooth muscle cells. (2000) (25)
- Association of Serum Antibody Levels against TUBB2C with Diabetes and Cerebral Infarction (2015) (25)
- Sod1 Loss Induces Intrinsic Superoxide Accumulation Leading to p53-Mediated Growth Arrest and Apoptosis (2013) (25)
- Urinary podocalyxin levels were associated with urinary albumin levels among patients with diabetes (2016) (24)
- Identification and characterization of high glucose and glucosamine responsive element in the rat osteopontin promoter. (2003) (24)
- Phosphatidylinositol 3-kinase activity is required for the activation process of focal adhesion kinase by platelet-derived growth factor. (1996) (24)
- Risk Factors of Atherosclerotic Diseases (2007) (24)
- Mexiletine suppresses nodal persistent sodium currents in sensory axons of patients with neuropathic pain (2010) (24)
- Goals of dyslipidemia management. (2007) (24)
- Impact of combinatorial dysfunctions of Tet2 and Ezh2 on the epigenome in the pathogenesis of myelodysplastic syndrome (2017) (23)
- PPARβ/δ activation of CD300a controls intestinal immunity (2014) (23)
- Halofuginone prevents extracellular matrix deposition in diabetic nephropathy. (2009) (23)
- Syringaresinol Reverses Age-Related Skin Atrophy by Suppressing FoxO3a-Mediated Matrix Metalloproteinase-2 Activation in Copper/Zinc Superoxide Dismutase-Deficient Mice. (2019) (22)
- Development of the Dementia Assessment Sheet for Community‐based Integrated Care System 8‐items, a short version of the Dementia Assessment Sheet for Community‐based Integrated Care System 21‐items, for the assessment of cognitive and daily functions (2018) (22)
- GERMLINE DELETION OF ARMC5 IN FAMILIAL PRIMARY MACRONODULAR ADRENAL HYPERPLASIA. (2015) (22)
- Pituitary Adenylate Cyclase-Activating Polypeptide Protects Glomerular Podocytes from Inflammatory Injuries (2015) (22)
- Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open‐label, blinded‐endpoint, randomized controlled study (PRIME‐V study) (2019) (22)
- Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus‐6–associated acute limbic encephalitis after unrelated bone marrow transplantation (2013) (22)
- Postpartum risk of diabetes and predictive factors for glucose intolerance in East Asian women with gestational diabetes. (2018) (22)
- Altered cerebral blood flow in the anterior cingulate cortex is associated with neuropathic pain (2018) (22)
- Diagnosis of atherosclerosis. Executive Summary of the Japan Atherosclerosis Society (JAS) Guidelines for the Diagnosis and Prevention of Atherosclerotic Cardiovascular Diseases in Japan―2012 Version. (2014) (22)
- KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis. (2019) (21)
- Circulating soluble LR11/SorLA levels are highly increased and ameliorated by chemotherapy in acute leukemias. (2012) (21)
- Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor α Modulator (SPPARMα): Pooled Analysis of Phase 2 and 3 Studies in Dyslipidemic Patients with or without Statin Combination (2019) (21)
- Metabolic syndrome. (2008) (21)
- Treatment - therapeutic lifestyle modification. (2008) (21)
- DOCK2 is involved in the host genetics and biology of severe COVID-19 (2022) (20)
- Serum SH3BP5-specific Antibody Level is a Biomarker of Atherosclerosis (2017) (20)
- Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes (2018) (20)
- Successful treatment with recombinant soluble thrombomodulin of two cases of sinusoidal obstructive syndrome/hepatic veno‐occlusive disease after bone marrow transplantation (2011) (20)
- Matricellular protein CCN3 mitigates abdominal aortic aneurysm. (2016) (20)
- Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients (2019) (20)
- Extramedullary blast crisis of chronic myelogenous leukemia as an initial presentation☆ (2013) (20)
- Clinical outcome and mechanism of soft tissue calcification in Werner syndrome. (2008) (20)
- Treatment A) lifestyle modification: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. (2013) (19)
- Comparison in decision-making between bulimia nervosa, anorexia nervosa, and healthy women: influence of mood status and pathological eating concerns (2015) (19)
- Diagnosis of Atherosclerosis (2014) (19)
- Direct activation of STAT5 by ETV6‐LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis (2011) (19)
- Platelet-derived Growth Factor Activates p 38 Mitogen-activated Protein Kinase through a Ras-dependent Pathway That Is Important for Actin Reorganization and Cell Migration (1999) (19)
- A Toxic Conformer of Aβ42 with a Turn at 22–23 is a Novel Therapeutic Target for Alzheimer’s Disease (2017) (18)
- Reduction of Smad3 accelerates re-epithelialization in a murine model of colitis. (2004) (18)
- Hepatocellular carcinoma development in diabetic patients: a nationwide survey in Japan (2021) (18)
- The Role of Smad3-Dependent TGF-β Signal in Vascular Response to Injury (2006) (18)
- Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3. (2002) (18)
- Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients (2011) (18)
- Ezh 2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia (2012) (17)
- N-3 polyunsaturated fatty acids improve lipoprotein particle size and concentration in Japanese patients with type 2 diabetes and hypertriglyceridemia: a pilot study (2018) (17)
- Incidence and Characteristics of Metabolic Disorders and Vascular Complications in Individuals with Werner Syndrome in Japan (2012) (17)
- EXTENSION OF THE LIFE SPAN IN PATIENTS WITH WERNER SYNDROME (2008) (17)
- PDGF-BB triggered cytoplasmic calcium responses in cells with endogenous or stably transfected PDGF beta-receptors. (1995) (17)
- Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack (2017) (16)
- Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer (2012) (16)
- Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia. (2016) (16)
- Diabetes mellitus. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. (2014) (16)
- An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice (2012) (16)
- Posterior reversible encephalopathy syndrome in an adult patient with acute lymphoblastic leukemia after remission induction chemotherapy (2012) (15)
- Inheritable abnormal lipoprotein metabolism in Werner's syndrome similar to familial hypercholesterolaemia (1990) (15)
- An Anti-Deoxyhypusine Synthase Antibody as a Marker of Atherosclerosis-Related Cerebral Infarction, Myocardial Infarction, Diabetes Mellitus, and Chronic Kidney Disease (2017) (15)
- Differential Interaction of CrkII Adaptor Protein with Platelet-Derived Growth Factor α- and β-Receptors Is Determined by Its Internal Tyrosine Phosphorylation (2000) (15)
- Glucagon‐like peptide‐1 secretion by direct stimulation of L cells with luminal sugar vs non‐nutritive sweetener (2011) (15)
- Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity (2021) (15)
- Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development. (2018) (14)
- Fibronectin stimulates transcription of the platelet-derived growth factor beta-receptor in cultured rat aortic smooth muscle cells. (1998) (14)
- Intestinal Epithelial Cells with Impaired Autophagy Lose Their Adhesive Capacity in the Presence of TNF-α (2011) (14)
- Treatment B) drug therapy: executive summary of the Japan Atherosclerosis Society(JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan--2012 version. (2013) (14)
- A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation (2016) (14)
- Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan (2020) (14)
- Elevated Adiponectin Antibody Levels in Sera of Patients with Atherosclerosis-Related Coronary Artery Disease, Cerebral Infarction and Diabetes Mellitus (2016) (14)
- Lipoprotein(a) Is a Risk Factor for Diabetic Retinopathy in the Elderly (1994) (14)
- Combination of cilostazol and probucol protected podocytes from lipopolysaccharide-induced injury by both anti-inflammatory and anti-oxidative mechanisms (2017) (14)
- LR11: a novel biomarker identified in follicular lymphoma (2013) (13)
- CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet (2019) (13)
- Metabolic predictors of ischemic heart disease and cerebrovascular attack in elderly diabetic individuals: difference in risk by age (2013) (13)
- Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation. (2000) (13)
- Aldosterone Reduction Rate After Saline Infusion Test May Be A Novel Prediction In Patients With Primary Aldosteronism. (2020) (13)
- Werner syndrome: a model for sarcopenia due to accelerated aging (2017) (13)
- Cardiovascular disease risk factors other than dyslipidemia. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan - 2012 version. (2013) (12)
- Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan (2021) (12)
- Prednisolone-responsive Postpartum IgG4-related Hypophysitis (2017) (12)
- EARLY AMELIORATION OF INSULIN RESISTANCE AND REDUCTION OF INTERLEUKIN‐6 IN WERNER SYNDROME USING PIOGLITAZONE (2008) (12)
- Achieving LDL cholesterol target levels <1.81 mmol/L may provide extra cardiovascular protection in patients at high risk: Exploratory analysis of the Standard Versus Intensive Statin Therapy for Patients with Hypercholesterolaemia and Diabetic Retinopathy study (2018) (12)
- Detection of MYD88 L265P mutation by next-generation deep sequencing in peripheral blood mononuclear cells of Waldenström’s macroglobulinemia and IgM monoclonal gammopathy of undetermined significance (2017) (11)
- Recent Trends in WRN Gene Mutation Patterns in Individuals with Werner Syndrome (2017) (11)
- Serum anti‐LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases (2020) (11)
- Importance of lipid levels in elderly diabetic individuals: baseline characteristics and 1-year survey of cardiovascular events. (2008) (11)
- [Effects of aging and hyperlipidemia on plasma osteopontin level]. (1999) (11)
- Factors associated with the efficiency of PBSC collection in POEMS syndrome patients undergoing autologous PBSC transplantation (2012) (11)
- Dose‐dependent reduction in body weight with LIK066 (licogliflozin) treatment in Japanese patients with obesity (2020) (11)
- Sodium-Glucose Cotransporter 2 Inhibitors Improve Chronic Diabetic Macular Edema (2020) (11)
- Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in InsrP1195L/+ mice fed high-fat-diet (2015) (11)
- Sitagliptin Improves Postprandial Hyperglycemia by Inhibiting Glucagon Secretion in Werner Syndrome With Diabetes (2013) (11)
- Elevated levels of autoantibodies against DNAJC2 in sera of patients with atherosclerotic diseases (2020) (11)
- Mobilization of PBSCs in poor mobilizers with POEMS syndrome using G-CSF with plerixafor (2012) (11)
- Identification of an ubiquitin-ligation system for the epidermal-growth-factor receptor--herbimycin A induces in vitro ubiquitination in rabbit-reticulocyte lysate. (1997) (10)
- DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes. (2021) (10)
- Effect of empagliflozin on cardiorenal outcomes and mortality according to body mass index: A subgroup analysis of the EMPA‐REG OUTCOME trial with a focus on Asia (2021) (10)
- Low-dose trimethoprim–sulfamethoxazole for Pneumocystis jiroveci pneumonia prophylaxis after allogeneic hematopoietic SCT (2011) (10)
- Astaxanthin Improves Nonalcoholic Fatty Liver Disease in Werner Syndrome with Diabetes Mellitus (2015) (10)
- Steroid metabolites for diagnosing and predicting clinicopathological features in cortisol-producing adrenocortical carcinoma (2020) (10)
- The role of Smad3-dependent TGF-beta signal in vascular response to injury. (2006) (10)
- The clinical characteristics of Asian patients with classical-type Hutchinson–Gilford progeria syndrome (2017) (9)
- Marked decrease in plasma apolipoprotein A-I and high density lipoprotein-cholesterol in a case with Werner syndrome. (2000) (9)
- RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting (2018) (9)
- Treatment B) Drug Therapy (2013) (9)
- Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing’s disease: a case report (2017) (9)
- Serum podocalyxin levels correlate with carotid intima media thickness, implicating its role as a novel biomarker for atherosclerosis (2018) (9)
- Sitagliptin Successfully Ameliorates Glycemic Control in Werner Syndrome With Diabetes (2012) (9)
- [Platelet derived growth factor (PDGF)]. (1996) (9)
- Identification of Serum Anti-GADD34 Antibody as a Common Marker ofDiabetes Mellitus and Parkinson Disease (2017) (9)
- Absolute risk of cardiovascular disease and lipid management targets. (2013) (9)
- Hypoglycemia due to ectopic secretion of insulin-like growth factor-I in a patient with an isolated sarcoidosis of the spleen. (2010) (9)
- Clonal immunoglobulin λ light‐chain gene rearrangements detected by next generation sequencing in POEMS syndrome (2018) (9)
- GLS2 is a tumor suppressor and a regulator of ferroptosis in hepatocellular carcinoma. (2022) (9)
- Prognostic impact of serum soluble LR11 in newly diagnosed diffuse large B-cell lymphoma: A multicenter prospective analysis. (2016) (8)
- Comparison of Visceral Fat Reduction by Ipragliflozin and Metformin in Elderly Type 2 Diabetes Patients: Sub-Analysis of a Randomized-Controlled Study (2020) (8)
- Atorvastatin ameliorates podocyte injury in patients with type 2 diabetes complicated with dyslipidemia. (2013) (8)
- Acute myeloid leukemia concurrent with spinal epidural extramedullary myeloid sarcoma accompanied by a high CD25 expression and the FLT3-ITD mutation. (2014) (8)
- Effects of ipragliflozin versus metformin in combination with sitagliptin on bone and muscle in Japanese patients with type 2 diabetes mellitus: Subanalysis of a prospective, randomized, controlled study (PRIME‐V study) (2020) (8)
- Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging Stud (2017) (8)
- Atorvastatin-induced dermatomyositis in a 47-year-old woman with Sjögren’s syndrome (2015) (8)
- A Pooled Analysis of Pemafibrate Phase II/III Clinical Trials Indicated Significant Improvement in Glycemic and Liver Function-related Parameters (2018) (8)
- Glucagonoma With Necrolytic Migratory Erythema: Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene (2018) (8)
- Association between serum anti-ASXL2 antibody levels and acute ischemic stroke, acute myocardial infarction, diabetes mellitus, chronic kidney disease and digestive organ cancer, and their possible association with atherosclerosis and hypertension (2020) (8)
- Familial hypercholesterolemia. (2014) (8)
- Altered serum level of matrix metalloproteinase‐9 and its association with decision‐making in eating disorders (2017) (8)
- Association of Serum Anti-Prolylcarboxypeptidase Antibody Marker with Atherosclerotic Diseases Accompanied by Hypertension (2017) (8)
- Role of phospholipase A2 in expression of the scavenger pathway in cultured aortic smooth muscle cells stimulated with phorbol 12-myristate 13-acetate. (1994) (8)
- Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double‐blind placebo‐controlled clinical trials (2021) (8)
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- Discussion on Update and Future Perspectives in Management of Dyslipidemia: with Emphasis on Familial Hypercholesterolemia (2017) (0)
- Metabolism and Endocrinology as Crossroads of Generalism and Specialism (2019) (0)
- The Effect of 1α (OH) D_3 and Interferon-α in a Case of Cutaneous T-cell Lymphoma (1991) (0)
- 1699-P: Mechanisms and Roles of Foxo1-Akt Negative Feedback Pathway in Adipocytes (2020) (0)
- Homozygous familial lipoprotein lipase deficiency without obvious coronary artery stenosis. (2022) (0)
- Predictive model and risk engine web application for surgical site infection risk in perioperative patients with type 2 diabetes (2022) (0)
- Itchy papules on the back and neck of a young woman. (2022) (0)
- 1P-0148 Analyses of the expression profile of genes associated with diabetic glomerulopathy in purely isolated mice glomeruli (2003) (0)
- 70 - Superoxide Dismutase 1 Deficiency Causes Age-Related Skin Pathologies Accompanied by p53 Activation (2014) (0)
- Role of Mutant p53 in Regulation of Three Dimensional Malignant Formation of Breast Cancer Via SREBP-dependent Cholesterol Synthetic Pathway (2016) (0)
- Table of Contents (1993) (0)
- A Toxic Conformer of Aβ42 with a Turn at 22–23 is a Novel Therapeutic Target for Alzheimer’s Disease (2017) (0)
- The use of phosphotyrosine-peptides for the determination of the specificity of SHC-protein binding to PDGF β-receptor (1995) (0)
- 147-OR: Glucose Intolerance of Hereditary Progeria Werner Syndrome and Cellular Senescence in Their Adipose Tissue (2022) (0)
- [Cutting-edge of medicine; dysfunction of adipose tissue and insulin resistance]. (2013) (0)
- PO012 PREDICTORS OF ISCHEMIC HEART DISEASE AND CEREBROVASCULAR ATTACK IN DIABETIC INDIVIDUALS: LESSONS FROM 9.1 YEARS STUDY OF 4014 DIABETIC PATIENTS INCLUDING 1016 LATE ELDERLY OLDER THAN 75Y.O. – DIFFERENCE OF RISK BY AGE (2014) (0)
- [Metabolic diseases and cerebral white matter lesions]. (2007) (0)
- NK-104, A 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR, REDUCES OSTEOPONTIN EXPRESSION BY RAT AORTIC SMOOTH MUSCLE CELLS (2002) (0)
- 121-OR: Activation of FoxO1 Induces Akt Phosphorylation and Mimics the Metabolic Functions of Insulin without Proliferative Effects on 3T3-L1 Adipocytes (2021) (0)
- 1153-P: Sodium-Glucose Cotransporter-2 Inhibitors Increase Food Intake via a Mechanism That Acts on the Central Nervous System Involving Phosphorylation of Adenosine Monophosphate-Activated Protein Kinase in the Lateral Hypothalamus (2021) (0)
- Guidelines for the Diagnosis and Treatment of Adult Familial Hypercholesterolemia 2022. (2023) (0)
- Anagrelide Inhibits Proliferation and Platelet Generation in Immortalized Megakaryocyte Progenitor Cell Lines Established from Human Induced Pluripotent Stem Cells (2018) (0)
- Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia. (2023) (0)
- 1962-P: Role of Transcription Factor TCF21 in Adipocyte Progenitor Cells of Visceral Fat (2020) (0)
- Case of sarcomatoid carcinoma occurring in a patient with Werner syndrome (2016) (0)
- Identification of Clonal Immunoglobulin λ Light-Chain Gene Rearrangements in AL Amyloidosis Using Next Generation Sequencing (2019) (0)
- Identification of Clonal Immunoglobulin λ Light-Chain Gene Rearrangements in AL Amyloidosis using Next Generation Sequencing. (2021) (0)
- Vitamin E and Atherosclerosis: From the Viewpoint of Arterial Wall Cell Function (1993) (0)
- CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet (2019) (0)
- Selective deprivation of the toxic conformer of Aβ ameliorated behavioral abnormalities in Alzheimer' disease model without affecting senile plaque deposition (2015) (0)
- Marked decrease in plasma apolipoprotein A-I and HDL-C in a case with Werner syndrome (2000) (0)
- The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms. (2023) (0)
- [Abdominal ultrasonography and dual energy X-ray absorptiometry for measurements of intra-abdominal adipose tissue]. (2011) (0)
- Abstract 12622: The Modeling of Werner Syndrome by Induced Pluripotent Stem Cells (2015) (0)
- 1P-0205 Functional analysis about the role of Smad3-dependent transforming growth factor-β signaling in neointimal hyperplasia (2003) (0)
- 23-OR: Loss of the Transcription Factor Tcf21 in Adult Podocytes Leads to Susceptibility in Diabetic Kidney Disease (2022) (0)
- Role of KDM2B and Non-Canonical PRC1.1 As a Tumor Suppressor in T-ALL (2018) (0)
- RELATIONSHIP BETWEEN SILENT HYPOGLYCEMIA AND TREATMENTS, OR HBA1C IN ELDERLY PATIENTS WITH DIABETES (2017) (0)
- 4. Bariatric Surgery (2015) (0)
- [Werner syndrome and metabolic syndrome]. (2006) (0)
- Exhausted T Cells Characterized By Upregulation of Specific Transcription Factors Are Increased in a Mouse Model of De Novo Mature B Cell Neoplasms (2022) (0)
- A novel homozygous frameshift mutation in the APOA1 gene associated with marked high-density lipoprotein deficiency. (2022) (0)
- American women ( aged 30 − 55 years at Women (2008) (0)
- Enhanced expression of osteopontin by high glucose: Involvement of osteopontin in diabetic vascular diseases (2000) (0)
- DEVELOPMENT OF QUALITY INDICATORS FOR CONTINUITY AND COORDINATION OF CARE IN ELDERS IN JAPAN (2017) (0)
- A method for estimating visceral fat from the elasticity of lumbar subcutaneous fat (2014) (0)
- Diagnosis and Pathogenesis of Progeroid Syndromes (2019) (0)
- Fibroblasts derived from patients of Werner syndrome exhibit cellular senescence due to WRN deficiency (2017) (0)
- Targeted Disruption of Smad3 Results in Enhanced Neointimal Hyperplasia through Alteration of Smooth Muscle Cell Response to TGF-β (2003) (0)
- Case of Werner syndrome with significant improvement of refractory skin ulcer despite fibroblast cellular senescence (2023) (0)
- Clinical Usefulness of the Growth Hormone–Releasing Peptide-2 Test for Hypothalamic-Pituitary Disorder (2022) (0)
- Comparison in decision-making between bulimia nervosa, anorexia nervosa, and healthy women: influence of mood status and pathological eating concerns (2015) (0)
- Discussion on Management of Metabolic and Endocrine Disorders for General Practitioners (2019) (0)
- [The Update of Obesity Syndrome: Molecular Mechaniam, Pathophysiology and Therapies. Topics: II. Recent Topics on Care and Treatment of the Obesity Syndrome; 4. Bariatric surgery]. (2015) (0)
- ODP301 Corticotroph Macroadenomas with Extensions to Third Ventricle: Four Case Reports (2022) (0)
- MON-188 Characterization and Categorization Based on Genotype-Biochemical Phenotype Association in Fructose-1,6-Bisphosphatase Deficiency (2019) (0)
- RNaseH2A Downregulation Drives Chromosomal DNA Fragmentation and Accumulation of RNA-DNA Hybrids in Senescent Cells (2020) (0)
- Factors Associated with Relapse of Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy in Japanese Subjects: A Subgroup Analysis of J-SMART Study (2023) (0)
- [Programs for Continuing Medical Education 2016: A Session: 5. Management of Life Style-related Disease to Prevent Atherosclerosis]. (2017) (0)
- SUN-020 Analyses Of Clock Gene Expressions In Peripheral Leukocytes In Hypercortisolism (2019) (0)
- The elderly. (2014) (0)
- Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer (2023) (0)
- Molecular mechanism of pathogenesis of the progeria. (2016) (0)
- Soluble LR11, a Novel Acute Leukemia Marker, Drastically Induces WT1 mRNA Expression Together with Synergic Activation of Gatas, and the Migration Activity (2012) (0)
- Statements. (2021) (0)
- [Blood pressure management in the very elderly]. (2007) (0)
- SOD2 deficiency in chondrocytes accelerates age-related osteoarthritis in mice (2014) (0)
- Combinatorial Epigenetic Aberration Propagates in Myelodysplastic Syndrome in the Setting of Concurrent Loss of Tet2 and Ezh2 (2015) (0)
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