Kozo Kaibuchi
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Computer Science
Kozo Kaibuchi's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Kozo Kaibuchi's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. (1982) (4275)
- Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase) (1996) (3007)
- Small GTP-binding proteins. (1992) (2476)
- Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)* (1996) (2049)
- Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase (1997) (1112)
- Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. (1996) (1089)
- Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. (1999) (1041)
- Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association (1998) (871)
- Rho-Kinase/ROCK: A Key Regulator of the Cytoskeleton and Cell Polarity (2010) (815)
- GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity (2005) (807)
- Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. (2001) (784)
- CRMP-2 binds to tubulin heterodimers to promote microtubule assembly (2002) (732)
- Neuronal polarity: from extracellular signals to intracellular mechanisms (2007) (655)
- Rac1 and Cdc42 Capture Microtubules through IQGAP1 and CLIP-170 (2002) (631)
- Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation* (1997) (613)
- Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo (1999) (594)
- Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation. (1983) (569)
- CRMP-2 induces axons in cultured hippocampal neurons (2001) (531)
- Regulation and functions of Rho-associated kinase. (2000) (520)
- Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. (1998) (513)
- Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. (2004) (496)
- Roles of Rho-family GTPases in cell polarisation and directional migration. (2003) (474)
- Synaptic dysregulation in a human iPS cell model of mental disorders (2014) (456)
- Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. (1992) (454)
- Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N (1996) (447)
- Rho-family GTPases in cadherin-mediated cell — cell adhesion (2001) (435)
- [Neuronal polarity]. (2008) (430)
- Akt/PKB regulates actin organization and cell motility via Girdin/APE. (2005) (425)
- Long-Term Treatment With a Rho-Kinase Inhibitor Improves Monocrotaline-Induced Fatal Pulmonary Hypertension in Rats (2004) (401)
- Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin (1993) (398)
- Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells (2002) (394)
- PAR-6–PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1 (2005) (391)
- Thrombin Inactivates Myosin Light Chain Phosphatase via Rho and Its Target Rho Kinase in Human Endothelial Cells* (1998) (362)
- Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G (1995) (356)
- Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. (2007) (356)
- IQGAP1: a key regulator of adhesion and migration (2005) (345)
- Regulation of microtubules in cell migration. (2005) (339)
- The Ras Target AF-6 Interacts with ZO-1 and Serves as a Peripheral Component of Tight Junctions in Epithelial Cells (1997) (327)
- Identification of IQGAP as a Putative Target for the Small GTPases, Cdc42 and Rac1* (1996) (327)
- Rho-Kinase–Mediated Contraction of Isolated Stress Fibers (2001) (325)
- Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival (2005) (324)
- Phosphorylation of Adducin by Rho-Kinase Plays a Crucial Role in Cell Motility (1999) (321)
- GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction (1987) (321)
- Rho-kinase-mediated pathway induces enhanced myosin light chain phosphorylations in a swine model of coronary artery spasm. (1999) (315)
- Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. (1993) (312)
- Cooperative roles of various membrane phospholipids in the activation of calcium-activated, phospholipid-dependent protein kinase. (1981) (311)
- Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. (2001) (302)
- Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation. (2000) (297)
- Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. (1990) (295)
- Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites. (2001) (293)
- Role of the PAR-3–KIF3 complex in the establishment of neuronal polarity (2004) (287)
- The COOH Terminus of Rho-kinase Negatively Regulates Rho-kinase Activity* (1999) (281)
- Synergistic functions of phorbol ester and calcium in serotonin release from human platelets. (1983) (280)
- Rho-associated Kinase of Chicken Gizzard Smooth Muscle* (1999) (277)
- Phosphorylation by Rho Kinase Regulates CRMP-2 Activity in Growth Cones (2005) (261)
- p140Sra-1 (Specifically Rac1-associated Protein) Is a Novel Specific Target for Rac1 Small GTPase* (1998) (253)
- Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. (2004) (252)
- CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth (2003) (251)
- Myosin II activation promotes neurite retraction during the action of Rho and Rho‐kinase (1998) (246)
- Essential Roles for GSK-3s and GSK-3-Primed Substrates in Neurotrophin-Induced and Hippocampal Axon Growth (2006) (243)
- Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm. (2000) (238)
- CRMP-2 Is Involved in Kinesin-1-Dependent Transport of the Sra-1/WAVE1 Complex and Axon Formation (2005) (238)
- Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta. (2000) (234)
- Spatial regulation of VEGF receptor endocytosis in angiogenesis (2013) (233)
- Phosphorylation of Moesin by Rho-associated Kinase (Rho-kinase) Plays a Crucial Role in the Formation of Microvilli-like Structures* (1998) (233)
- PIP3 is involved in neuronal polarization and axon formation (2004) (232)
- Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase (2000) (231)
- Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. (2001) (230)
- Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension. (2001) (230)
- Integrin Activation and Matrix Binding Mediate Cellular Responses to Mechanical Stretch* (2005) (229)
- Identification of AF-6 and Canoe as Putative Targets for Ras (*) (1996) (227)
- Phosphorylation of Vimentin by Rho-associated Kinase at a Unique Amino-terminal Site That Is Specifically Phosphorylated during Cytokinesis* (1998) (221)
- Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells. (2008) (221)
- Regulation of the Association of Adducin with Actin Filaments by Rho-associated Kinase (Rho-kinase) and Myosin Phosphatase* (1998) (219)
- Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system. (1999) (218)
- Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase (1998) (217)
- Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue* (1998) (216)
- Long-Term Inhibition of Rho-Kinase Suppresses Left Ventricular Remodeling After Myocardial Infarction in Mice (2004) (215)
- PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. (1998) (210)
- DISC1 Regulates the Transport of the NUDEL/LIS1/14-3-3ε Complex through Kinesin-1 (2007) (209)
- Cdc42 and Rac1 Regulate the Interaction of IQGAP1 with β-Catenin* (1999) (209)
- Regulation of Cross-linking of Actin Filament by IQGAP1, a Target for Cdc42* (1997) (206)
- Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases. (1999) (206)
- Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). (2006) (203)
- Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. (1988) (199)
- Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts. (2001) (199)
- Important Role of Rho-kinase in the Pathogenesis of Cardiovascular Inflammation and Remodeling Induced by Long-Term Blockade of Nitric Oxide Synthesis in Rats (2002) (196)
- Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation (2007) (195)
- Cytoskeletal Rearrangements and Transcriptional Activation of c-fos Serum Response Element by Rho-kinase* (1997) (191)
- A Mass Conserved Reaction–Diffusion System Captures Properties of Cell Polarity (2006) (191)
- Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins. (1991) (189)
- Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells. Reconstitution with Gi or Go of the plasma membranes ADP-ribosylated by pertussis toxin. (1986) (189)
- Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts. (1986) (189)
- AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation (2010) (188)
- Novel role of microtubules in thrombin‐induced endothelial barrier dysfunction (2004) (187)
- Tubulin and CRMP‐2 complex is transported via Kinesin‐1 (2005) (186)
- Establishment of a tissue-specific RNAi system in C. elegans. (2007) (185)
- Role of CRMP-2 in neuronal polarity. (2004) (181)
- Phospholipid turnover in hormone action. (1984) (180)
- Rho-Kinase Mediates Angiotensin II-Induced Monocyte Chemoattractant Protein-1 Expression in Rat Vascular Smooth Muscle Cells (2001) (179)
- Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes. (1985) (178)
- Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. (2009) (176)
- Roles of Disrupted-In-Schizophrenia 1-Interacting Protein Girdin in Postnatal Development of the Dentate Gyrus (2009) (176)
- Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: Role of Rho‐dependent mechanisms (2004) (173)
- Roles of Rho-associated Kinase in Cytokinesis; Mutations in Rho-associated Kinase Phosphorylation Sites Impair Cytokinetic Segregation of Glial Filaments (1998) (171)
- Rho-Kinase Is Involved in Macrophage-Mediated Formation of Coronary Vascular Lesions in Pigs In Vivo (2000) (170)
- Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway. (2006) (168)
- Synergistic action of protein kinase C and calcium for histamine release from rat peritoneal mast cells. (1984) (167)
- Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. (2008) (165)
- Phosphatidylinositol turnover in platelet activation; calcium mobilization and protein phosphorylation. (1982) (163)
- A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. (1991) (161)
- The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. (1999) (156)
- IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth (2007) (156)
- Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. (2004) (154)
- Myosin phosphatase-targeting subunit 1 regulates mitosis by antagonizing polo-like kinase 1. (2008) (153)
- Role of Rho-kinase in regulation of insulin action and glucose homeostasis. (2005) (151)
- DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. (2007) (149)
- Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact. (2003) (149)
- Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. (2004) (148)
- Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase. (1992) (147)
- Membrane phospholipid metabolism and signal transduction for protein phosphorylation. (1984) (144)
- Key Regulators in Neuronal Polarity (2005) (143)
- Role of Rho and Rho kinase in the activation of volume‐regulated anion channels in bovine endothelial cells (1999) (141)
- The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans. (2002) (141)
- Still life, a Protein in Synaptic Terminals of Drosophila Homologous to GDP-GTP Exchangers (1997) (140)
- Role of Rho-Associated Kinase in Neointima Formation After Vascular Injury (2001) (140)
- Phosphorylation of Glial Fibrillary Acidic Protein at the Same Sites by Cleavage Furrow Kinase and Rho-associated Kinase* (1997) (138)
- Myelin-associated Glycoprotein Inhibits Microtubule Assembly by a Rho-kinase-dependent Mechanism* (2006) (138)
- Phosphorylation of CLASP2 by GSK-3β regulates its interaction with IQGAP1, EB1 and microtubules (2009) (138)
- Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil. (2006) (137)
- Synaptic development is controlled in the periactive zones of Drosophila synapses. (2000) (137)
- Sema4D/plexin‐B1 activates GSK‐3β through R‐Ras GAP activity, inducing growth cone collapse (2006) (135)
- Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins. (1992) (134)
- Pioneering Axons Regulate Neuronal Polarization in the Developing Cerebral Cortex (2014) (133)
- Two functionally different domains of rabphilin-3A, Rab3A p25/smg p25A-binding and phospholipid- and Ca(2+)-binding domains. (1993) (133)
- Activation of protein kinase C by non-phorbol tumor promoter, mezerein. (1984) (133)
- Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. (1998) (131)
- Expression of a Constitutively Active Phosphatidylinositol 3-Kinase Induces Process Formation in Rat PC12 Cells (1997) (131)
- Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. (2011) (130)
- Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments (1999) (129)
- The Ras Target AF-6 is a Substrate of the Fam Deubiquitinating Enzyme (1998) (128)
- Ras‐dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta. (1994) (126)
- Phosphorylation of ERM proteins at filopodia induced by Cdc42 (2000) (125)
- Induction of protein kinase C activation and Ca2+ mobilization by fibroblast growth factor in Swiss 3T3 cells (1985) (124)
- Inhibitory action of guanosine 3', 5'-monophosphate on thrombin-induced phosphatidylinositol turnover and protein phosphorylation in human platelets. (1981) (124)
- Signaling Networks in Neuronal Polarization (2006) (123)
- Binding of APC and dishevelled mediates Wnt5a‐regulated focal adhesion dynamics in migrating cells (2010) (122)
- Identification of calponin as a novel substrate of Rho-kinase. (2000) (120)
- Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition (2007) (120)
- Long-Term Inhibition of Rho-kinase Ameliorates Hypoxia-Induced Pulmonary Hypertension in Mice (2006) (119)
- Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2. (2005) (117)
- Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF (2001) (115)
- A possible role of protein kinase C in signal-induced lysosomal enzyme release. (1983) (112)
- Association of Ash/Grb-2 with dynamin through the Src homology 3 domain. (1994) (112)
- Regulated CD44 Cleavage under the Control of Protein Kinase C, Calcium Influx, and the Rho Family of Small G Proteins* (1999) (111)
- Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C. (1989) (111)
- DISC1 Regulates Neurotrophin-Induced Axon Elongation via Interaction with Grb2 (2007) (110)
- Identification of the stef Gene That Encodes a Novel Guanine Nucleotide Exchange Factor Specific for Rac1* (1999) (108)
- Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases. (1997) (108)
- Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse (2011) (107)
- Stimulation of Phosphatidylinositol-4-phosphate 5-Kinase by Rho-Kinase* (2000) (107)
- Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins. (1990) (106)
- Design and synthesis of Rho kinase inhibitors (I). (2004) (105)
- Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. (2014) (104)
- IDENTIFICATION OF YWHAE, A GENE ENCODING 14-3-3EPSILON, AS A NOVEL SUSCEPTIBILITY GENE FOR SCHIZOPHRENIA (2008) (104)
- Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. (2001) (103)
- Numb controls E-cadherin endocytosis through p120 catenin with aPKC (2011) (103)
- Interaction of the Small G Protein RhoA with the C Terminus of Human Phospholipase D1* (1999) (103)
- Cell adhesion and Rho small GTPases. (1999) (101)
- Interaction between ROCK II and Nucleophosmin/B23 in the Regulation of Centrosome Duplication (2006) (99)
- Balance between Activities of Rho Kinase and Type 1 Protein Phosphatase Modulates Turnover of Phosphorylation and Dynamics of Desmin/Vimentin Filaments* (1999) (99)
- Axon specification in hippocampal neurons (2002) (98)
- Both stimulatory and inhibitory GDP/GTP exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins. (1992) (98)
- Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. (1991) (98)
- Entrapment of Rho ADP-ribosylated by Clostridium botulinum C3 Exoenzyme in the Rho-Guanine Nucleotide Dissociation Inhibitor-1 Complex* (2003) (97)
- RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. (2004) (97)
- Identification of Tau and MAP2 as novel substrates of Rho‐kinase and myosin phosphatase (2003) (97)
- Neuronal polarization (2015) (96)
- Adenovirus-Mediated Transfer of Dominant-Negative Rho-Kinase Induces a Regression of Coronary Arteriosclerosis in Pigs In Vivo (2001) (96)
- A possible target protein for smg-25A/rab3A small GTP-binding protein. (1992) (96)
- Possible involvement of RAS-encoded proteins in glucose-induced inositolphospholipid turnover in Saccharomyces cerevisiae. (1986) (95)
- Gene transfer of dominant negative Rho kinase suppresses neointimal formation after balloon injury in pigs. (2000) (94)
- AF-6 Controls Integrin-mediated Cell Adhesion by Regulating Rap1 Activation through the Specific Recruitment of Rap1GTP and SPA-1* (2003) (93)
- Genome-Wide Association Study of Schizophrenia in a Japanese Population (2011) (91)
- Involvement of IQGAP1, an Effector of Rac1 and Cdc42 GTPases, in Cell-Cell Dissociation during Cell Scattering (2001) (91)
- Cadherin-mediated intercellular adhesion and signaling cascades involving small GTPases. (2009) (90)
- Long-Term Treatment With a Specific Rho-Kinase Inhibitor Suppresses Cardiac Allograft Vasculopathy in Mice (2004) (90)
- Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase (2001) (89)
- Enhancement of the actions of smg p21 GDP/GTP exchange protein by the protein kinase A-catalyzed phosphorylation of smg p21. (1991) (89)
- Nuclear Rho Kinase, ROCK2, Targets p300 Acetyltransferase* (2006) (89)
- A protein kinase C cDNA without the regulatory domain is active after transfection in vivo in the absence of phorbol ester (1989) (89)
- A Role for Rho-kinase in Rho-controlled Phospholipase D Stimulation by the m3 Muscarinic Acetylcholine Receptor* (1999) (89)
- The deubiquitinating enzyme Fam interacts with and stabilizes β‐catenin (1999) (88)
- Counteraction of calcium-activated, phospholipid-dependent protein kinase activation by adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in platelets. (1982) (88)
- Inhibitory action of adenosine 3',5'-monophosphate on phosphatidylinositol turnover: difference in tissue response. (1982) (87)
- Involvement of Rho-Kinase in Agonists-Induced Contractions of Arteriosclerotic Human Arteries (2002) (87)
- Regulation of neuronal migration, an emerging topic in autism spectrum disorders (2016) (87)
- Survival of Developing Motor Neurons Mediated by Rho GTPase Signaling Pathway through Rho-Kinase (2004) (86)
- A role of calcium-activated, phospholipid-dependent protein kinase in platelet-activating factor-induced serotonin release from rabbit platelets. (1982) (86)
- Phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by protein kinase N. (2000) (85)
- Unc5B associates with LARG to mediate the action of repulsive guidance molecule (2009) (85)
- 14-3-3ε and ζ Regulate Neurogenesis and Differentiation of Neuronal Progenitor Cells in the Developing Brain (2014) (84)
- Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility. (2012) (84)
- Collapsin response mediator protein‐2 accelerates axon regeneration of nerve‐injured motor neurons of rat (2003) (83)
- Small GTPase RhoD suppresses cell migration and cytokinesis (1999) (83)
- Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2* (2008) (83)
- TAG-1–assisted progenitor elongation streamlines nuclear migration to optimize subapical crowding (2013) (82)
- A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping. (1998) (82)
- CaMKII phosphorylates collapsin response mediator protein 2 and modulates axonal damage during glutamate excitotoxicity (2009) (82)
- Role of protein kinase C in transmembrane signaling (1985) (81)
- A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains. (1997) (80)
- Extracellular and Intracellular Signaling for Neuronal Polarity. (2015) (79)
- IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver. (2013) (78)
- The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin. (1999) (78)
- Involvement of Rho‐kinase in hypertensive vascular disease —a novel therapeutic target in hypertension (2001) (78)
- Pasteurella multocida toxin increases endothelial permeability via Rho kinase and myosin light chain phosphatase. (1998) (77)
- The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility (2012) (76)
- Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration (2012) (75)
- RhoA and Rho Kinase Regulate the Epithelial Na+/H+ Exchanger NHE3 (2000) (74)
- Rho Kinase Promotes Alloimmune Responses by Regulating the Proliferation and Structure of T Cells1 (2003) (74)
- Rho/Rho-Kinase Pathway in Brain Stem Contributes to Blood Pressure Regulation via Sympathetic Nervous System: Possible Involvement in Neural Mechanisms of Hypertension (2003) (74)
- Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo (2016) (73)
- Ras-induced transformation and signaling pathway. (1999) (73)
- Distribution of Rho-kinase in the bovine brain. (1999) (72)
- Girdin Is an Intrinsic Regulator of Neuroblast Chain Migration in the Rostral Migratory Stream of the Postnatal Brain (2011) (72)
- Cdc42, Rac1, and their effector IQGAP1 as molecular switches for cadherin-mediated cell-cell adhesion. (1999) (71)
- Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells. (2007) (70)
- A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein (1991) (70)
- A Novel GTPase-activating Protein for R-Ras (*) (1995) (70)
- Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN. (1997) (68)
- FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development (2001) (68)
- An Open Conformation of Switch I Revealed by the Crystal Structure of a Mg2+-free Form of RHOA Complexed with GDP (2000) (67)
- Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein (1991) (67)
- IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics. (2015) (67)
- Elongation Factor-1α Is a Novel Substrate of Rho-Associated Kinase (2000) (67)
- In vivo interaction of AF-6 with activated Ras and ZO-1. (1999) (67)
- Roles of cell-autonomous mechanisms for differential expression of region-specific transcription factors in neuroepithelial cells. (1996) (66)
- Site‐Specific Phosphorylation of Neurofilament‐L Is Mediated by Calcium/Calmodulin‐Dependent Protein Kinase II in the Apical Dendrites During Long‐Term Potentiation (2000) (66)
- Rho‐kinase and myosin II activities are required for cell type and environment specific migration (2005) (65)
- Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho‐kinase (2005) (65)
- Kinase-interacting substrate screening is a novel method to identify kinase substrates (2015) (64)
- Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP* (2009) (64)
- Rho/Rho-Kinase Pathway in the Brainstem Contributes to Hypertension Caused by Chronic Nitric Oxide Synthase Inhibition (2004) (64)
- A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase. (1993) (64)
- Rab3A GTPase-activating protein-inhibiting activity of Rabphilin-3A, a putative Rab3A target protein. (1993) (63)
- Characterization of the interaction between RhoA and the amino‐terminal region of PKN (1996) (62)
- smg/rap1/Krev-1 p21s inhibit the signal pathway to the c-fos promoter/enhancer from c-Ki-ras p21 but not from c-raf-1 kinase in NIH3T3 cells. (1992) (62)
- The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase. (1993) (62)
- Regulation of myosin phosphatase through phosphorylation of the myosin-binding subunit in platelet activation. (1997) (61)
- IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A (2001) (60)
- Identification and characterization of Drosophila homolog of Rho-kinase. (1999) (60)
- CRMP‐2 directly binds to cytoplasmic dynein and interferes with its activity (2009) (60)
- Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity (2015) (59)
- Molecular Mechanisms of Axon Specification and Neuronal Disorders (2006) (59)
- Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye. (1997) (58)
- Two LIM domain proteins and UNC-96 link UNC-97/pinch to myosin thick filaments in Caenorhabditis elegans muscle. (2007) (58)
- Identification of a Novel -Catenin-Interacting Protein (2000) (57)
- Radial Glial Cell–Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site (2015) (57)
- Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation (1998) (57)
- NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted‐In‐Schizophrenia 1 (DISC1) (2011) (56)
- Involvement of Girdin in the Determination of Cell Polarity during Cell Migration (2012) (56)
- Reconstitution of dynamic microtubules with Drosophila XMAP215, EB1, and Sentin (2012) (56)
- Single-Cell Memory Regulates a Neural Circuit for Sensory Behavior. (2016) (56)
- Parallel Coiled-coil Association of the RhoA-binding Domain in Rho-kinase* (2003) (55)
- Local Application of Neurotrophins Specifies Axons Through Inositol 1,4,5-Trisphosphate, Calcium, and Ca2+/Calmodulin–Dependent Protein Kinases (2011) (54)
- Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition (2011) (54)
- Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus. (2017) (54)
- EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells (2011) (54)
- Discovery of long-range inhibitory signaling to ensure single axon formation (2017) (53)
- Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells. (2006) (52)
- Role of the Cytoskeleton in Mediating cAMP-dependent Protein Kinase Inhibition of the Epithelial Na+/H+ Exchanger NHE3* (2001) (52)
- Disruption of Rho signal transduction upon cell detachment (2004) (52)
- Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues. (2012) (52)
- Phosphorylation and activation of mitogen-activated protein kinase by kainic acid-induced seizure in rat hippocampus. (1994) (51)
- Domain- and site-specific phosphorylation of bovine NF-L by Rho-associated kinase. (1998) (51)
- Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator. (1994) (51)
- The Insert Region of RhoA Is Essential for Rho Kinase Activation and Cellular Transformation (2001) (51)
- Rho‐kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia (2007) (50)
- Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632. (2006) (50)
- Calcium and phosphatidylinositol turnover as signalling for transmembrane control of protein phosphorylation. (1981) (50)
- Elevation of cytoplasmic free calcium concentration by stable thromboxane A2 analogue in human platelets. (1983) (50)
- Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain (2005) (49)
- Activation of the serum response element and 12-O-tetradecanoylphorbol-13-acetate response element by the activated c-raf-1 protein in a manner independent of protein kinase C. (1989) (49)
- Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation. (1993) (49)
- TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases (2009) (48)
- Regulatory machinery of UNC‐33 Ce‐CRMP localization in neurites during neuronal development in Caenorhabditis elegans (2005) (48)
- Localization of the gene coding for myosin phosphatase, target subunit 1 (MYPT1) to human chromosome 12q15-q21. (1997) (48)
- Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice (2013) (48)
- Activation of the c-fos serum-response element by the activated c-Ha-ras protein in a manner independent of protein kinase C and cAMP-dependent protein kinase. (1990) (48)
- Alterations of GABAergic and dopaminergic systems in mutant mice with disruption of exons 2 and 3 of the Disc1 gene (2014) (48)
- S100P Is a Novel Interaction Partner and Regulator of IQGAP1* (2010) (47)
- Role of the C-terminal region of smg p21, a ras p21-like small GTP-binding protein, in membrane and smg p21 GDP/GTP exchange protein interactions. (1991) (47)
- LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression (2012) (47)
- Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway (2001) (46)
- Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. (2006) (45)
- Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA (2014) (45)
- The keratin-binding protein Albatross regulates polarization of epithelial cells (2008) (44)
- A Proteomic Approach for Comprehensively Screening Substrates of Protein Kinases Such as Rho-Kinase (2010) (43)
- Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation (2015) (42)
- TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation (2015) (42)
- Identification of sonic hedgehog-responsive genes using cDNA microarray. (2001) (41)
- Interaction of Sec4 with GDI proteins from bovine brain, Drosophila melanogaster and Saccharomyces cerevisiae (1993) (41)
- Membrane phospholipid turnover, receptor function and protein phosphorylation. (1982) (41)
- Chimeric MLL products with a Ras binding cytoplasmic protein AF6 involved in t(6;11) (q27;q23) leukemia localize in the nucleus (1997) (41)
- Neuronal polarization in vivo: Growing in a complex environment (2014) (41)
- Isolation of the interacting molecules with GEX-3 by a novel functional screening. (2002) (41)
- Interaction of Rho‐kinase with myosin II at stress fibres (2004) (40)
- Formation of a phorbol ester-binding fragment from protein kinase C by proteolytic digestion. (1986) (40)
- Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs (2019) (39)
- Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure. (2005) (39)
- Molecular cloning of the human cDNA for a stimulatory GDP/GTP exchange protein for c-Ki-ras p21 and smg p21. (1992) (39)
- Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi. (2010) (38)
- Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway (2016) (38)
- Elongation factor-1 alpha is a novel substrate of rho-associated kinase. (2000) (38)
- Partial purification and characterization of GDP dissociation stimulator (GDS) for the rho proteins from bovine brain cytosol. (1990) (38)
- Identification as beta-adducin of a protein interacting with rabphilin-3A in the presence of Ca2+ and phosphatidylserine. (1994) (37)
- NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1) (2011) (37)
- Neuronal Polarity: Positive and Negative Feedback Signals (2019) (37)
- The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module (2009) (37)
- The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration (2012) (36)
- Identification of a novel beta-catenin-interacting protein. (2000) (36)
- Hypoxia-induced upregulation of endothelial small G protein RhoA and Rho-kinase/ROCK2 inhibits eNOS expression (2006) (36)
- Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation (2018) (36)
- Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice: An in vivo microdialysis study (2010) (36)
- ERK2-Mediated Phosphorylation of Par3 Regulates Neuronal Polarization (2013) (36)
- Ca2+‐independent phospholipase A2‐dependent sustained Rho‐kinase activation exhibits all‐or‐none response (2006) (35)
- Activation of moesin and adducin by Rho-kinase downstream of Rho. (1999) (35)
- Role for Daple in non‐canonical Wnt signaling during gastric cancer invasion and metastasis (2015) (35)
- Phosphorylation Signals in Striatal Medium Spiny Neurons. (2016) (35)
- Phosphorylation of smg p21B/rap1B p21 by cyclic GMP‐dependent protein kinase (1992) (34)
- Rho-associated kinase phosphorylates desmin, the myogenic intermediate filament protein, at unique amino-terminal sites. (1998) (33)
- Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin (2014) (33)
- Sustained Elevation of Serum Cortisol Level Causes Sensitization of Coronary Vasoconstricting Responses in Pigs In Vivo: A Possible Link Between Stress and Coronary Vasospasm (2006) (33)
- TRIM27/MRTF-B-dependent integrin β1 expression defines leading cells in cancer cell collectives. (2014) (33)
- Activation of Ca2+/calmodulin-dependent protein kinase II within post-synaptic dendritic spines of cultured hippocampal neurons. (2000) (33)
- Neuronal Per Arnt Sim (PAS) Domain Protein 4 (NPAS4) Regulates Neurite Outgrowth and Phosphorylation of Synapsin I* (2012) (33)
- Regulation of cytoskeleton and cell adhesion by Rho targets. (1999) (33)
- Inhibition of the action of the stimulatory GDP/GTP exchange protein for smg p21 by the geranylgeranylated synthetic peptides designed from its C-terminal region. (1991) (32)
- TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases* (2009) (32)
- Transforming and c-fos promoter/enhancer-stimulating activities of a stimulatory GDP/GTP exchange protein for small GTP-binding proteins. (1992) (32)
- Co-localization of FAM and AF-6, the mammalian homologues of Drosophila faf and canoe, in mouse eye development (2000) (32)
- Proteomic screening for Rho-kinase substrates by combining kinase and phosphatase inhibitors with 14-3-3ζ affinity chromatography. (2012) (31)
- An Alu-linked Repetitive Sequence Corresponding to 280 Amino Acids Is Expressed in a Novel Bovine Protein, but Not in Its Human Homologue* (1997) (31)
- Smooth muscle contraction by small GTPase Rho. (2002) (31)
- Regulators of small GTPases. (2007) (31)
- The role of selective transport in neuronal polarization (2011) (30)
- Myosin binding subunit of smooth muscle myosin phosphatase at the cell-cell adhesion sites in MDCK cells. (1997) (30)
- Direct interaction of Dysbindin with the AP-3 complex via its μ subunit (2009) (30)
- Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics (2015) (30)
- The posttranslational processing of ras p21 is critical for its stimulation of yeast adenylate cyclase (1992) (29)
- Purification and Characterization of REKS from Xenopus Eggs (1995) (29)
- Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site (2013) (29)
- Proteomic analysis reveals novel binding partners of dysbindin, a schizophrenia‐related protein (2009) (29)
- Changes in E-cadherin associated with cytoplasmic molecules in well and poorly differentiated endometrial cancer (2000) (28)
- Spatially and temporally specific expression in mouse hippocampus of Usp9x, a ubiquitin‐specific protease involved in synaptic development (2005) (28)
- Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors. (2019) (28)
- Involvement of Ca2+ in platelet‐derived growth factor‐induced expression of c‐myc oncogene in Swiss 3T3 fibroblasts (1985) (28)
- RhoGEF12 controls cardiac remodeling by integrating G protein– and integrin-dependent signaling cascades (2013) (28)
- Prostacyclin Does Not Inhibit Rho-Kinase: An Implication for the Treatment of Pulmonary Hypertension (2005) (27)
- Combination of arachidonic acid and guanosine 5'-O-(3-thiotriphosphate) induce translocation of rac p21s to membrane and activation of NADPH oxidase in a cell-free system. (1993) (27)
- Regulation of the GTPase cycle of the neuronally expressed Ras-like GTP-binding protein Rab3A. (1993) (26)
- LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP (2019) (26)
- Stoichiometric interaction of smg p21 with its GDP/GTP exchange protein and its novel action to regulate the translocation of smg p21 between membrane and cytoplasm. (1991) (26)
- Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation. (2007) (25)
- Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters. (1984) (25)
- Identification of Rare, Single-Nucleotide Mutations in NDE1 and Their Contributions to Schizophrenia Susceptibility. (2015) (25)
- Inhibition of chemotactic peptide-induced phosphoinositide hydrolysis by phorbol esters through the activation of protein kinase C in differentiated human leukemia (HL-60) cells. (1986) (24)
- LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends (2015) (23)
- Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons (2019) (23)
- Rhoa and Rho-kinase regulate the epithelial Na+/H+ exchanger NHE3: role of myosin light chain phosphorylation (2000) (23)
- A Novel NE-dlg/SAP102-associated Protein, p51-nedasin, Related to the Amidohydrolase Superfamily, Interferes with the Association between NE-dlg/SAP102 and N-Methyl-d-aspartate Receptor* (1999) (23)
- Roles of IQGAP1 in cell polarization and migration. (2005) (23)
- ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk (2020) (22)
- Translocation of Ki-ras p21 between membrane and cytoplasm by smg GDS. (1993) (22)
- The smg GDS-induced activation of smg p21 is initiated by cyclic AMP-dependent protein kinase-catalyzed phosphorylation of smg p21. (1991) (22)
- PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions (2016) (22)
- PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a (2016) (22)
- Prognostic implication and biological roles of RhoH in acute myeloid leukaemia (2008) (22)
- Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3‐kinase (PI3‐kinase) as Par3 partners by proteomic analysis (2010) (21)
- PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity (2015) (21)
- Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of its Interaction with Actin. (2019) (20)
- Latent process genes for cell differentiation are common decoders of neurite extension length (2012) (20)
- Purification and in vitro activity of Rho-associated kinase. (2000) (20)
- Localization of the gene coding for ROCK II/Rho kinase on human chromosome 2p24. (1999) (20)
- Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells. (2002) (20)
- A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology. (2017) (20)
- Flexible Search for Single-Axon Morphology during Neuronal Spontaneous Polarization (2011) (19)
- Analysis of the VAV3 as candidate gene for schizophrenia: evidences from voxel-based morphometry and mutation screening. (2013) (19)
- Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development (2003) (19)
- Vimentin‐Ser82 as a memory phosphorylation site in astrocytes (2006) (19)
- Immunohistochemical evaluation of the GABAergic neuronal system in the prefrontal cortex of a DISC1 knockout mouse model of schizophrenia (2016) (19)
- Enhancement of collagen‐induced phosphoinositide turnover by thromboxane A2 analogue through Ca2+ mobilization in human platelets (1985) (18)
- Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes. (2011) (18)
- Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology (2018) (18)
- Mutation of ARHGAP9 in patients with coronary spastic angina (2010) (18)
- Rabphilin-3A binds to a M(r) 115,000 polypeptide in a phosphatidylserine- and Ca(2+)-dependent manner. (1995) (18)
- Rho small G protein and cytoskeletal control. (1994) (18)
- A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance (2015) (18)
- DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway. (2012) (18)
- Plk1 phosphorylates CLIP-170 and regulates its binding to microtubules for chromosome alignment. (2014) (17)
- Regulation of Vascular Endothelial Growth Factor Receptor Function in Angiogenesis by Numb and Numb-Like (2015) (16)
- Impairment of the tyrosine hydroxylase neuronal network in the orbitofrontal cortex of a genetically modified mouse model of schizophrenia (2011) (16)
- The Polymorphism of YWHAE, a Gene Encoding 14-3-3Epsilon, and Brain Morphology in Schizophrenia: A Voxel-Based Morphometric Study (2014) (16)
- Inhibition of Rho-Kinase in the Brainstem Augments Baroreflex Control of Heart Rate in Rats (2004) (16)
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- Enhancement of secretagogue-induced phosphoinositide turnover and amylase secretion by bile acids in isolated rat pancreatic acini. (1986) (16)
- The polymorphism of YWHAE, a gene encoding 14-3-3epsilon, and orbitofrontal sulcogyral pattern in patients with schizophrenia and healthy subjects (2014) (16)
- Phospholipid localization implies microglial morphology and function via Cdc42 in vitro (2017) (16)
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- Comparison of the modes of action of Ca2+ ionophore A23187 and thrombin in protein kinase C activation in human platelets (1985) (15)
- Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein. (1994) (15)
- Developing novel methods to search for substrates of protein kinases such as Rho-kinase. (2015) (14)
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- Stimulation of Synaptic Vesicle Exocytosis by the Mental Disease Gene DISC1 is Mediated by N-Type Voltage-Gated Calcium Channels (2016) (14)
- Regulation of E-Cadherin-Mediated Cell-Cell Adhesion by Rho Family GTPases (2005) (13)
- FLT3/ ITD regulates leukaemia cell adhesion through α4β1 integrin and Pyk2 signalling (2011) (13)
- Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models (2019) (13)
- Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency. (2015) (13)
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- Localization of rabphilin-3A, a putative target protein for Rab3A, at the sites of Ca(2+)-dependent exocytosis in PC12 cells. (1994) (12)
- Possible involvement of protein kinase C in interleukin-1 production by mouse peritoneal macrophages. (1986) (12)
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- Activation of protein kinase C by the action of 9,11-epithio-11,12-methano-thromboxane A2 (STA2), a stable analogue of thromboxane A2, in human platelets. (1986) (11)
- Inhibition of the Action of a Stimulatory GDP/GTP Exchange Protein for smg p21 hy Acidic Membrane Phospholipids (1991) (11)
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- A stimulatory GDP / GTP exchange protein for smg p 21 is active on the post-translationally processed form of cKi-ras p 21 and rhoA p 21 ( ras p 21 / rho p 21 / prenylation ) (8)
- Phosphorylation of Gephyrin in Zebrafish Mauthner Cells Governs Glycine Receptor Clustering and Behavioral Desensitization to Sound (2019) (8)
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- Identification of the Kinase-Substrate Recognition Interface between MYPT1 and Rho-Kinase (2022) (2)
- Corrigendum to “Design and synthesis of Rho kinase inhibitors (I)”: [Bioorg. Med. Chem. 12 (2004) 2115] (2004) (2)
- Identification of YWHAE, a gene encoding 14-3-3ɛ, as a novel susceptibility gene for schizophrenia (2007) (2)
- RhoGEF-mediated vasoconstriction in hypertension (2013) (2)
- [Roles of IQGAP1 in E-cadherin-mediated cell-cell adhesion]. (2006) (2)
- IRR is involved in glucose-induced endocytosis after insulin secretion. (2019) (2)
- [Current perspective on the pathogenesis of schizophrenia from the viewpoint of risk factors such as DISC1 (corrected)]. (2010) (2)
- Note added in proof (1984) (2)
- RhoA/C and the Actin Cytoskeleton (2005) (2)
- Neuronal polarity in 2011 (2011) (2)
- CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1 (2020) (1)
- Phosphorylation Signals Downstream of Dopamine Receptors in Emotional Behaviors: Association with Preference and Avoidance (2022) (1)
- Crystallization and preliminary crystallographic analysis of the Rho-binding domain of bovine Rho-kinase. (2000) (1)
- SOCS3-microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury. (2021) (1)
- Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein. (2017) (1)
- Crystal Structure of Human RhoA Complex with the Effector Domain of PKN (1999) (1)
- [Motility of fibroblast cells and its regulatory mechanisms]. (2006) (1)
- [Involvement of small GTPase Rho in cardiovascular diseases]. (2002) (1)
- This information is current as of T Cells Structureby Regulating the Proliferation and Rho Kinase Promotes Alloimmune Responses (2003) (1)
- 1115 Still life, a protein in synaptic terminals homologous to GDP-GTP exchangers (1997) (1)
- brain barrier in HIV-1 encephalitis ( HIVE ) Rho-mediated regulation of tight junctions during monocyte migration (2006) (1)
- Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior. (2022) (1)
- Prickle2 and Igsf9b coordinately regulate the cytoarchitecture of the axon initial segment. (2020) (1)
- GDP/GTP Exchange Proteins for Small GTP-Binding Proteins (1993) (1)
- GDP-Bound Rab27a Dissociates from the Endocytic Machinery in a Phosphorylation-Dependent Manner after Insulin Secretion. (2019) (1)
- Transforming and c-fos promoter/enhancer-stimulating activities of a GDP/GTP exchange protein for small GTP-binding proteins. (1991) (1)
- COMMENTARY Cell adhesion and Rho small GTPases (1999) (1)
- Low-resolution crystal structure of the Tiam2 PHCCEx domain (2009) (0)
- 2P021 Structural and functional studies of CLIP-170(Proteins-structure and structure-function relationship,Poster Presentations) (2007) (0)
- [Involvement of small GTPase Rho and Rho-kinase in the pathogenesis of hypertension and hypertensive target organ damage]. (2004) (0)
- 1P208 Structural analysis of native membrane cytoskeleton under cryoelectron microscope (2005) (0)
- Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology (2018) (0)
- [Neuronal polarity]. (2006) (0)
- [Molecular mechanisms regulating neuronal polarity via phosphorylation signaling]. (2007) (0)
- ERK2-mediated phosphorylation of Par3 affects axon specification by modulating its interaction with KIF3A (2010) (0)
- A Mammalian Inhibitory GDP/GTPExchange Protein (GDPDissociation Inhibitor) forsmgp25AIs Active ontheYeastSEC4Protein (1991) (0)
- Molecular Networks for the Regulation of Cell Polarization in Migrating Cells and Neurons (2012) (0)
- Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain (2019) (0)
- Expression and function of Mash-1 during transition from self-renewal to neuronal differentiation in forebrain-derived neural stem cells (1997) (0)
- Hypertension Sympathetic Nervous System : Possible Involvement in Neural Mechanisms of Rho / Rho-Kinase Pathway in Brain Stem Contributes to Blood Pressure Regulation via (2003) (0)
- FAM, a ubiquitin specific protease, is essential for early mouse development (2000) (0)
- Rho-kinase in cultured human fibroblasts Stress fiber organization regulated by MLCK and (2016) (0)
- Structural analysis of the membrane undercoat in cultured neural growth cone (2003) (0)
- Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models (2020) (0)
- Key role of Rho/Rho-kinase signaling in hindbrain motor axon patterning (2007) (0)
- ROLE OF RHO FAMILY GTPASES IN REGULATION OF CELL MIGRATION AND POLARITY (2005) (0)
- Establishment of an in vivo calcium imaging method to evaluate neuronal activity in mice carrying mutations of Arhgap10 gene (2022) (0)
- Neurotrophins regulate neuronal polarity acting through inositol 1, 4, 5-trisphosphate/Ca2+/calmodulin-dependent protein kinase kinase (2011) (0)
- Rho-kinase regulates neurite retraction downstream of the small GTPase Rho (1998) (0)
- Protein Kinase C and Transmembrane Signaling of Grouwth Factors in Swiss 3T3 Fibroblasts (1986) (0)
- [Regulation of cytoskeleton and cell adhesion by small GTPases]. (1997) (0)
- Long-range inhibitory signaling regulates robust neuronal polarization (2016) (0)
- A novel function of Ca2+ in axon specification acting through the CaMKK/CaMKI pathway (2010) (0)
- [Signal transduction pathways mediated by small GTPases and protein kinases]. (1996) (0)
- Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene. (2022) (0)
- Title Discovery of long-range inhibitory signaling to ensure singleaxon formation (2018) (0)
- Administration of NMDA receptor antagonist causes down-regulation of DISC1 expression and over migration of newly generated neurons in the adult hippocampus (2010) (0)
- Disrupted-In-Schizoprenia-1 regulates transport of neuronal mRNA (2010) (0)
- CRMP-2, Slp1 and Rab27B mediate anterograde transport of TrkB (2007) (0)
- Histological investigation in the brain of genetically modified mouse of schizophrenia (2011) (0)
- A Protein Kinase C cDNAwithout theRegulatory DomainIsActive after Transfection InVivointheAbsence ofPhorbol Ester (1989) (0)
- S1-3 Observation of the membrane-associated cytoskeleton : From light microscopy to electron microscopy(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY) (2005) (0)
- Rats Inhibition of Rho-Kinase in the Brainstem Augments Baroreflex Control of Heart Rate in (2004) (0)
- Discovery of long-range inhibitory signaling to ensure single axon formation (2017) (0)
- Npas4 regulates neurite outgrowth and phosphoryation of synapsin I (2011) (0)
- Expression of FAM, a ubiquitin specific protease in mouse embryos (1999) (0)
- Crystal structure of human RhoA complexed with a GTP analogue (1998) (0)
- KANPHOS (Kinase-Associated Neural PHOspho-Signaling), a comprehensive database for specific substrates of kinases (2018) (0)
- Role of still life - RAC cascade in the synapses (1998) (0)
- LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways (2022) (0)
- A proteomic approach for comprehensively screening substrates of protein kinases (2010) (0)
- CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP (2000) (0)
- Pathophysiological functions of DISC1 as a component of RNA granule (2009) (0)
- Proteomic analyses of novel binding partners of Atoh1 and Ptf1a, cerebellar development-related proteins (2011) (0)
- [Small GTPases and their effectors]. (2012) (0)
- The role of RHOA-mediated signaling in heart failure (2018) (0)
- Disrupted-in-Schizoprenia-1 regulates transport of neuronal mRNA for neural plasticity (2011) (0)
- LRRK1regulates the transport and maturation of autophagosomes (2016) (0)
- Coiled-coil structure of the RhoA-binding domain in Rho-kinase (2003) (0)
- RhoH Downregulates Rac Through RhoGAP Family Protein (2011) (0)
- Molecular Genetic Study of Schizophrenia Based on Neurodevelopmental Hypothesis (2007) (0)
- Proteomic analysis reveals novel binging partner of DISC1, a candidate risk gene of schizophrenia (2011) (0)
- Inositol 1,4,5-trisphosphate induced Ca2+ release is involved in neurite outgrowth and neuronal polarization (2009) (0)
- Reward signals downstream of dopamine D1 receptors. (2016) (0)
- Targeting of Tiam1 to focal adhesion through talin for Rac1 activation and cell migration (2010) (0)
- Multi-step and context-dependent functions of Meis1 in cerebellar granule cell development (2016) (0)
- Preface (2006) (0)
- The role of Npas4 in neurite outgrowth and phosphorylated synapsin I expression in Neuro2a cells and primary cultured hippocampal neurons (2010) (0)
- Synaptic dysregulation in a human iPSC model of major mental disorders (2014) (0)
- The small G protein superfamily--possible functions and modes of action. (1992) (0)
- KANPHOS (Kinase-Associated Phospho-Signaling) Platform - A comprehensive database for kinase-associated neural phosphorylation signaling (2019) (0)
- Molecular Mechanism of KCNQ Channels For Reward Behavior (2020) (0)
- ERK2 phosphorylates Par3 and controls its transport in axons (2011) (0)
- 3 Regulation of Axon Formation (2009) (0)
- Acetylcholine signaling in striatum/nucleus accumbens (2019) (0)
- Current perspective on the pathogenesis of schizophrenia from the viewpoint of risk factors such as DISC1 (Japanese Journal of Neuropsychopharmacology) (2011) (0)
- [Cell adhesion, cytoskeleton, and kidney diseases--with special reference to cytoskeleton and adhesion control by a low molecular weight GTP-binding protein Rho]. (1999) (0)
- Japanese Abstract (2020) (0)
- Identification of PI 3-kinase as an Slp1-interacting protein by proteomic analysis (2009) (0)
- DSCAM-Mediated Suppression of RapGEF2/Rap1 and N-Cadherin Regulates Neuronal Delamination and Migration (2019) (0)
- Role of small G proteins in neurotransmitter release (1992) (0)
- CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1 (1999) (0)
- Stress-impaired reward pathway promotes distinct feeding behavior patterns (2021) (0)
- A possible role of phosphatidylinositol turnover in thrombin-induced activation of human platelets (1981) (0)
- Structural basis of the Rho effector recognition (2002) (0)
- Molecular Cloning of the cDNA for Stimulatory GDP/GTP Exchange Protein for smg p2ls (ras p21-Like Small (2003) (0)
- Role of CRMP-2 in Neuronal Polarization (2007) (0)
- HUMAN RHOA COMPLEXED WITH GTP ANALOGUE (1998) (0)
- Role of Meis1 in the cerebellar development (2017) (0)
- Comprar Integrated Molecular Medicine for Neuronal and Neoplastic Disorders | Gen Sobue | 9781573316552 | Blackwell Publishing (2007) (0)
- Protein at the Same Sites by Cleavage Phosphorylation of Glial Fibrillary Acidic Communication (2013) (0)
- Molecular Cloning ofthecDNAforStimulatory GDP/GTP Exchange Protein forsmgp2ls(rasp21-Like Small GTP-Binding Proteins) andCharacterization of Stimulatory GDP/GTPExchange Protein (1991) (0)
- Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in medium spiny neurons (2018) (0)
- Analysis of CREB-binding proteins using DNA affinity beads. (2016) (0)
- Crystal structure of human RhoA^ complexed with GDP. (1999) (0)
- Phosphorylation of Shank3 by Rho-Kinase regulates surface translocation of NMDA and AMPA receptors in PSD (2018) (0)
- Scientists identify molecular mechanisms behind learning and memory (2022) (0)
- DARPP-32/protein phosphatase 1 regulates Rasgrp2 as a novel component of dopamine D1 receptor signaling in striatum (2022) (0)
- Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice (2018) (0)
- Disrupted-In-Schizoprenia-1 regulates transport of neuronal mRNA (2010) (0)
- Homeodomain-less MEIS1 suppresses CUL3-dependent ATOH1 degradation to regulate cerebellar granule cell development (2022) (0)
- Phenotypic analysis of DISC1 knockout mice (2010) (0)
- Crystal structure of the Tiam1 PHCCEx domain (2009) (0)
- Erratum: Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of rho-associated kinase in human osteoblasts (Biochemical and Biophysical Research Communications (2001) 287:2 (337-342)) (2001) (0)
- コラプシン反応媒介タンパク質‐2(CRMP‐2)による白血病関連RhoGEF(LARG)活性の抑制 (2002) (0)
- [Modes of action of protein kinase C and growth factors]. (1989) (0)
- Neuroscience 2009 Committee (2009) (0)
- Novel signal transduction in smooth muscle myosin phosphorylation (1999) (0)
- Conditional suppression of rho GTPase signaling pathway in specific neuronal types with Cre-loxP recombination driven by double lentiviral vector system (2010) (0)
- Cloning and analysis of STEF, a mouse homologue of Drosophila sif gene (1998) (0)
- Essential role of Rho signaling in cranial motor axon patterning (2009) (0)
- Poster #S66 THE POLYMORPHISM OF YWHAE, A GENE ENCODING 14-3-3EPSILON, AND ORBITOFRONTAL SULCOGYRAL PATTERN IN SCHIZOPHRENIA AND HEALTHY SUBJECTS (2014) (0)
- characterization of stimulatory GDP / GTP p 21-like small GTP-binding proteins ) and GDP / GTP exchange protein for smg p 21 s ( ras Molecular cloning of the cDNA for stimulatory (2003) (0)
- Regulation of DISC1 through phosphorylation by ERK (2007) (0)
- [Comparison of the mode of action of ras p 21 with those of protein kinase A and C in the gene expression]. (1991) (0)
- Induction of protein kinase C mobilization by fibroblast growth (1985) (0)
- Crystal structure of the Tiam2 PHCCEx domain (2009) (0)
- NMDA-induced activation of the CaMKII-RhoA-Rho-kinase pathway regulates aversive learning (2022) (0)
- LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport (2022) (0)
- MAPK-mediated phosphorylation of MKL2 regulates nuclear localization and transcriptional activity in striatal neurons (2018) (0)
- Dopamine-induced phosphorylation of NPAS4 through MAPK regulates reward-related learning and memory (2018) (0)
- PHOSPHOLIPID TURNOVER AS TRANSMEMBRANE SIGNALLING FOR PROTEIN PHOSPHORYLATION AND PLATELET ACTIVATION1 (1983) (0)
- RoleoftheC-Terminal Region ofsmgp25AinItsInteraction with Membranes andtheGDP/GTPExchange Protein (1991) (0)
- Remodeling Induced by Long-Term Blockade of Nitric Oxide Synthesis in Rats Important Role of Rho-kinase in the Pathogenesis of Cardiovascular Inflammation and (2002) (0)
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What Schools Are Affiliated With Kozo Kaibuchi?
Kozo Kaibuchi is affiliated with the following schools:
