Kwaku Ohene-Frempong
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Ghanaian pediatric hematologist-oncologist
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Medical Philosophy
Kwaku Ohene-Frempong's Degrees
- Doctorate Medicine Kwame Nkrumah University of Science and Technology
Why Is Kwaku Ohene-Frempong Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kwaku Ohene-Frempong was a Ghanaian pediatric hematologist-oncologist and an expert in sickle cell disease . Ohene-Frempong grew up in Ghana and was a standout athlete in track-and-field, later competing for Yale University as well as Ghana at the 1970 British Commonwealth Games. He continued his medical training in the United States, where he completed medical school, pediatrics residency and a pediatric hematology-oncology fellowship. With a professional interest in SCD, Ohene-Frempong was a physician and involved in public health initiatives at Tulane University School of Medicine in New Orleans, Louisiana, and later the Children's Hospital of Philadelphia in Pennsylvania. He continued professional relationships with Komfo Anokye Teaching Hospital in Kumasi, Ghana where he later became a full-time physician after retiring from CHOP. In Ghana, he established public health initiatives for SCD screening in newborns, as well as an SCD clinic for patients with the disease.
Kwaku Ohene-Frempong's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cerebrovascular accidents in sickle cell disease: rates and risk factors. (1998) (1629)
- A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group. (1995) (523)
- Sickle cell disease (2018) (475)
- Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. (1999) (437)
- Bone marrow transplantation for sickle cell disease. (1996) (372)
- Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease. (2000) (348)
- Enabling the genomic revolution in Africa (2014) (327)
- The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease. (1996) (291)
- Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease. (2001) (285)
- Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke. (2002) (227)
- 5‐hydroxymethyl‐2‐furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells †,‡ (2005) (225)
- Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. The Cooperative Study of Sickle Cell Disease. (1999) (224)
- Home management of sickle cell-related pain in children and adolescents: natural history and impact on school attendance (1995) (213)
- Stroke in sickle cell disease: demographic, clinical, and therapeutic considerations. (1991) (177)
- Silent infarcts in young children with sickle cell disease (2009) (172)
- Barriers to bone marrow transplantation for sickle cell anemia. (1996) (171)
- Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy. (2002) (161)
- Pulmonary, gonadal, and central nervous system status after bone marrow transplantation for sickle cell disease. (2010) (161)
- A modified transfusion program for prevention of stroke in sickle cell disease. (1992) (160)
- Effect of zinc supplementation on growth and body composition in children with sickle cell disease. (2002) (140)
- SCREENING NEWBORNS FOR SICKLE CELL DISEASE IN GHANA (2008) (139)
- Total and resting energy expenditure in children with sickle cell disease. (2000) (136)
- Epidemiology of human parvovirus B19 in children with sickle cell disease. (2004) (134)
- Effects of Delayed Pubertal Development, Nutritional Status, and Disease Severity on Longitudinal Patterns of Growth Failure in Children With Sickle Cell Disease (2007) (133)
- Neurologic complications after allogeneic marrow transplantation for sickle cell anemia. (1995) (132)
- Erythrocytapheresis therapy to reduce iron overload in chronically transfused patients with sickle cell disease. (1994) (127)
- Sickle Cell Disease: New Opportunities and Challenges in Africa (2013) (123)
- Body composition in children with sickle cell disease. (2002) (112)
- Low vitamin D status in children with sickle cell disease. (2004) (95)
- Sickle cell and the brain. (2001) (94)
- Indications for red cell transfusion in sickle cell disease. (2001) (94)
- Pulse oximetry and factors associated with hemoglobin oxygen desaturation in children with sickle cell disease. (1993) (93)
- Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study. (2002) (92)
- Serum levels of substance P are elevated in patients with sickle cell disease and increase further during vaso-occlusive crisis. (1998) (89)
- Trial of low doses of aspirin as prophylaxis in sickle cell disease. (1983) (88)
- Plasma zinc status, growth, and maturation in children with sickle cell disease. (1998) (86)
- Newborn screening for sickle cell disease in Europe: recommendations from a Pan‐European Consensus Conference (2018) (80)
- High risk of vitamin D deficiency in children with sickle cell disease. (2008) (79)
- Neurologic events after partial exchange transfusion for priapism in sickle cell disease. (1992) (77)
- Obstructive Sleep Apnea Syndrome in Sickle Cell Disease (1989) (76)
- Self-hypnosis training as an adjunctive treatment in the management of pain associated with sickle cell disease. (1997) (75)
- Alloimmunization to platelets in heavily transfused patients with sickle cell disease. (1996) (71)
- ACSM and CHAMP summit on sickle cell trait: mitigating risks for warfighters and athletes. (2012) (70)
- Erythropoietin and inhibitors of in vitro erythropoiesis in the development of anemia in children with renal disease. (1985) (66)
- Adequacy of dietary intake declines with age in children with sickle cell disease. (2007) (62)
- Bone Area and Bone Mineral Content Deficits in Children With Sickle Cell Disease (2005) (60)
- Psychological adjustment of adolescents with sickle cell disease: relations with demographic, medical, and family competence variables. (1998) (58)
- Sickle Cell Disease: Management Options and Challenges in Developing Countries (2013) (55)
- Comparison of magnetic resonance angiography and conventional angiography in sickle cell disease: clinical significance and reliability (1996) (55)
- Community Health Workers as Support for Sickle Cell Care. (2016) (54)
- Upper airway lymphoid tissue size in children with sickle cell disease. (2012) (52)
- Treatment Adherence in Children with Sickle Cell Disease: Disease-Related Risk and Psychosocial Resistance Factors (2002) (50)
- Different hematological phenotypes caused by the interaction of triplicated α‐globin genes and heterozygous β‐thalassemia (1997) (47)
- Periodic limb movements and disrupted sleep in children with sickle cell disease. (2011) (44)
- Newborn Screening for Sickle Cell Disease in Liberia: A Pilot Study (2016) (43)
- Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia (2007) (41)
- Screening U.S. college athletes for their sickle cell disease carrier status. (2011) (41)
- Psychological Adjustment of Children With Sickle Cell Disease: Family Functioning and Coping. (2004) (40)
- Headache in children with sickle cell disease: prevalence and associated factors. (2007) (39)
- Is treatment adherence associated with better quality of life in children with sickle cell disease? (2005) (39)
- Healthcare provision for sickle cell disease in Ghana: challenges for the African context (2008) (36)
- Vitamin A status, hospitalizations, and other outcomes in young children with sickle cell disease. (2004) (36)
- Modulation of erythrocyte arginase activity in sickle cell disease patients during hydroxyurea therapy (2005) (33)
- Pneumococcal colonization in children with sickle cell disease [see comment]. (1996) (30)
- Bone marrow transplantation for sickle cell anemia: Progress and prospects (2005) (30)
- Erythropoietin response to anaemia in children with sickle cell disease and Fanconi's hypoproliferative anaemia. (1985) (29)
- A multiperspective investigation of social competence in children with sickle cell disease. (1994) (28)
- Non‐invasive measurements of carboxyhemoglobin and methemoglobin in children with sickle cell disease (2012) (28)
- Nocturnal Enuresis in Pediatric Sickle Cell Disease (2001) (27)
- Partially oxygenated sickled cells: sickle-shaped red cells found in circulating blood of patients with sickle cell disease. (1994) (26)
- Markers of bone turnover are associated with growth and development in young subjects with sickle cell anemia (2008) (26)
- Use of hydroxyurea in children with sickle cell disease: what comes next? (1997) (25)
- Effect of erythrocytapheresis on arterial oxygen saturation and hemoglobin oxygen affinity in patients with sickle cell disease (1998) (25)
- Different hematological phenotypes caused by the interaction of triplicated alpha-globin genes and heterozygous beta-thalassemia. (1997) (24)
- Sickle cell anemia: intracranial stenosis and silent cerebral infarcts in children with low risk of stroke. (2014) (24)
- Empowering newborn screening programs in African countries through establishment of an international collaborative effort (2020) (24)
- Impact of acute illness on nutritional status of infants and young children with sickle cell disease. (2000) (24)
- Vitamin B6 Status of Children With Sickle Cell Disease (2002) (24)
- Transcranial Doppler ultrasonography in siblings with sickle cell disease (2003) (24)
- Sickle Cell Disease and Transcranial Doppler Imaging: Inter-Hemispheric Differences in Blood Flow Doppler Parameters (2011) (23)
- Clinical features of thalassemia. (1980) (23)
- 270 Newborn Screening for Sickle Cell Disease in Ghana (2005) (21)
- Transfusion and Chelation Practices in Sickle Cell Disease: A Regional Perspective (2011) (21)
- Sickle Cell Disease: Reference Values and Interhemispheric Differences of Nonimaging Transcranial Doppler Blood Flow Parameters (2011) (21)
- Transcranial Doppler ultrasonography in siblings with sickle cell disease (2003) (20)
- Using Formative Research to Develop a Counselor Training Program for Newborn Screening in Ghana (2015) (20)
- Concerted global effort to combat sickle cell disease: the first global congress on sickle cell disease in Accra, Ghana. (2011) (20)
- Linkage of alpha G-Philadelphia to alpha-thalassemia in African-Americans . (1980) (19)
- Respiratory muscle force and lung volume changes in a population of children with sickle cell disease (2013) (18)
- Collaborative study of marrow transplantation for sickle cell disease: Aspects specific for transplantation of hemoglobin disorders (1997) (17)
- Community engagement to inform the development of a sickle cell counselor training and certification program in Ghana (2016) (17)
- Energy expenditure and intake in children with sickle cell disease during acute illness. (2001) (17)
- Percentage of reversibly and irreversibly sickled cells are altered by the method of blood drawing and storage conditions. (1996) (17)
- Proceedings of a Sickle Cell Disease Ontology workshop — Towards the first comprehensive ontology for Sickle Cell Disease (2016) (17)
- Approaches to Transfusion Therapy and Iron Overload in Patients with Sickle Cell Disease: Results of an International Survey (2011) (16)
- Image analysis studies of the degree of irreversible deformation of sickle cells in relation to cell density and Hb F level (1993) (16)
- Relation Between Religious Perspectives and Views on Sickle Cell Disease Research and Associated Public Health Interventions in Ghana (2018) (15)
- Iron status of children with sickle cell disease. (2001) (15)
- Knowledge of Stroke Risk, Signs of Stroke, and the Need for Stroke Education among Children with Sickle Cell Disease and their Caregivers (2002) (15)
- Upper airway genioglossal activity in children with sickle cell disease. (2011) (14)
- Increased blood requirements during long-term transfusion therapy for sickle cell disease. (1991) (14)
- Brief report: parent perspectives of nutritional status and mealtime behaviors in children with sickle cell disease. (2004) (14)
- Alpha-gene deletions in black newborn infants with Hb Bart's (1980) (13)
- Prolongation of the prothrombin time and activated partial thromboplastin time in children with sickle cell disease (2006) (13)
- Stroke and elevated blood flow velocity in the anterior cerebral artery in sickle cell disease. (2004) (13)
- Plasma zinc is an insensitive predictor of zinc status: use of plasma zinc in children with sickle cell disease. (2002) (12)
- Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients (2015) (11)
- Combined use of nonmyelosuppressive nitrosourea analogues with hydroxyurea in the induction of F-cell production in a human erythroleukemic cell line. (2003) (11)
- Investigation of stroke in sickle cell disease by1H nuclear magnetic resonance spectroscopy (2004) (11)
- SickleInAfrica. (2020) (11)
- Capturing PLMS and their variability in children with sickle cell disease: does ankle activity monitoring measure up to polysomnography? (2012) (10)
- Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research. (2017) (10)
- Survival of F-reticulocytes in sickle cell disease. (1995) (9)
- Exposure of blood from patients with sickle cell disease to air changes the morphological, oxygen‐binding, and sickling properties of sickled erythrocytes (2006) (9)
- Beyond National Borders: A Global Perspective on Advances in Sickle Cell Disease Research and Management, and New Challenges in the Genome Era (2007) (9)
- No improvement in suboptimal vitamin A status with a randomized, double-blind, placebo-controlled trial of vitamin A supplementation in children with sickle cell disease. (2012) (9)
- Alpha-gene deletions in black newborn infants with Hb Bart's. (1980) (8)
- Limited septoplasty as treatment for recurrent epistaxis in a child with glanzmann's thrombasthenia (1987) (7)
- Organ damage in sickle cell disease study (ORDISS): protocol for a longitudinal cohort study based in Ghana (2017) (7)
- Establishing a Sickle Cell Disease Registry in Africa: Experience From the Sickle Pan-African Research Consortium, Kumasi-Ghana (2022) (7)
- Quantitative analysis of the degree of irreversible deformation of F cells and non-F cells and its relationship to cell density in sickle cell disease. (1994) (7)
- Disorders of Hemoglobin: Clinical and Pathophysiological Aspects of Sickle Cell Anemia (2009) (6)
- Sickle Cell Disease in Children: Accuracy of Imaging Transcranial Doppler Ultrasonography in Detection of Intracranial Arterial Stenosis (2012) (6)
- Exploring the Role of Shared Decision Making in the Consent Process for Pediatric Genomics Research in Cameroon, Tanzania, and Ghana (2019) (6)
- HB Shelby [β131(H9)GLN→LYS] in Association with HB S [β6(A3)GLU→VAL]: Characterization, Stability, and Effects on HB S Polymerization (1993) (6)
- HB Osler [β145(HC2)TYRàASP] Results from Posttranslational Modification (1997) (6)
- Implementing newborn screening for sickle cell disease in Korle Bu Teaching Hospital, Accra: Results and lessons learned (2021) (6)
- Identification of F-reticulocytes by two-stage fluorescence image cytometry. (1996) (6)
- Selected testing of newborns for sickle cell disease. (1989) (6)
- The Sickle Cell Disease Ontology: enabling universal sickle cell-based knowledge representation (2019) (5)
- Association of Pulsatility Index in the Middle Cerebral Artery with Intelligence Quotient in Children with Sickle Cell Disease (2012) (5)
- Persistent lymphadenopathy associated with hypertransfusion in sickle-cell disease. (1985) (4)
- Enablers and barriers to newborn screening for sickle cell disease in Africa: results from a qualitative study involving programmes in six countries (2022) (3)
- Sickling in vitro at venous and arterial oxygen tensions of reticulocytes from patients with sickle cell disease. (1995) (3)
- Non-Invasive Measurements of Carboxyhemoglobin and Methemoglobin in Pediatric Patients with Sickle Cell Disease. (2009) (2)
- Erythroid progenitors in the peripheral blood of children with sickle cell disease. (1994) (2)
- Hb Shelby [beta 131(H9)Gln-->Lys] in association with Hb S [beta 6(A3)Glu-->Val]: characterization, stability, and effects on Hb S polymerization. (1993) (2)
- α THALASSEMIA AND THE EXPRESSION OF HEMOGLOBIN G‐PHILADELPHIA * (1980) (2)
- Prevalence of Intracranial Stenosis and Silent Cerebral Infarcts in Children with Sickle Cell Anemia and Low Risk of Stroke (2013) (2)
- Thalassemia syndromes. Recent advances. (1987) (2)
- Hb Osler [beta 145(HC2)Tyr-->Asp] results from posttranslational modification. (1997) (2)
- Periodic limb movements and disrupted sleep in children with sickle cell disease (SLEEP (2011) 34, 7, (899-908)) (2012) (2)
- Stroke in Sickle Cell Disease (2007) (2)
- The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology (2022) (1)
- disease Epidemiology of human parvovirus B19 in children with sickle cell (2013) (1)
- The Six-Minute Walk Test In Children With Sickle Cell Disease (2010) (1)
- Utilization of Pneumococcal Vaccine and Penicillin Prophylaxis in Sickle Cell Disease in Three African Countries: Assessment among Healthcare Providers in SickleInAfrica (2021) (1)
- CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Safety of Hydroxyurea in Children With Sickle Cell Anemia: Results of the HUG-KIDS Study, a Phase I/II Trial (2016) (1)
- Parameters of vitamin A (VA) status in children with sickle cell disease (SCD) (2009) (0)
- Community engagement to inform the development of a sickle cell counselor training and certification program in Ghana (2016) (0)
- Filterability of freshly-collected sickle erythrocytes under venous oxygen pressure without exposure to air. (2015) (0)
- SQUAMOUS CELL CARCINOMA OF THE TONGUE OCCURING IN A PATIENT WITH FANCONIʼS APLASTIC ANEMIA IN THE POST BONE MARROW TRANSPLANT PERIOD (1990) (0)
- A Multidisciplinary Approach To Hemophilia At A New Regional Center; How Effective Is It? (1981) (0)
- Dietary Intake of Children with Sickle Cell Disease (SCD) Compared to the National Health and Nutrition Examination Survey (NHANES III) (2007) (0)
- A Novel High-Throughput Method for Evaluating deoxy-Hb S Solubility. (2006) (0)
- Concordant transcranial doppler ultrasonography velocities in sib-pairs with sickle cell disease (2000) (0)
- PLMS AND DISRUPTED SLEEP IN CHILDREN WITH SICKLE CELL DISEASE Periodic Limb Movements and Disrupted Sleep in Children with Sickle Cell Disease and disrupted sleep in children (2011) (0)
- UPPER AIRWAY ACTIVITY IN CHILDREN WITH SICKLE CELL DISEASE (2011) (0)
- Empowering newborn screening programs in African countries through establishment of an international collaborative effort (2020) (0)
- Respiratory Muscle Force And Lung Volume Changes In Children With Sickle Cell Disease (2012) (0)
- Effect of zinc supplementation on growth and body composition in children with sickle cell disease 1–3 (2002) (0)
- Development of multi-level standards of care recommendations for sickle cell disease: Experience from SickleInAfrica (2023) (0)
- Child health in a Ghanaian community (1975) (0)
- Resting Energy Expenditure and Dietary Intake in Vaso-occlusive Crisis in Children with Sickle Cell Disease † 583 (1998) (0)
- S129: IMPLEMENTATION OF HYDROXYUREA THERAPY FOR SICKLE CELL DISEASE ON A LARGE SCALE IN GHANA (2022) (0)
- SERUM ZINC AND COPPER, AND GROWTH AND BODY COMPOSITION IN CHILDREN WITH SICKLE CELL DISEASE (SCD). 932 (1996) (0)
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