Lee Chao
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Engineering Biology
Lee Chao's Degrees
- PhD Biomedical Engineering Stanford University
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(Suggest an Edit or Addition)Lee Chao's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Local Delivery of Human Tissue Kallikrein Gene Accelerates Spontaneous Angiogenesis in Mouse Model of Hindlimb Ischemia (2001) (202)
- Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland. (1994) (167)
- Transcription Factor Nuclear Factor κB Regulates the Inducible Expression of the Human B1 Receptor Gene in Inflammation* (1998) (156)
- Kallistatin is a new inhibitor of angiogenesis and tumor growth. (2002) (155)
- Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats. (1995) (146)
- Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence. (1992) (145)
- Human tissue kallikrein induces hypotension in transgenic mice. (1994) (137)
- Molecular Cloning, Tissue-specific Expression, and Cellular Localization of Human Prostasin mRNA (*) (1995) (136)
- Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. (1997) (134)
- Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. (2003) (130)
- Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease. (1996) (128)
- Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats. (1990) (124)
- Adrenomedullin Protects Against Myocardial Apoptosis After Ischemia/Reperfusion Through Activation of Akt-GSK Signaling (2004) (121)
- Adrenomedullin Gene Delivery Attenuates Hypertension, Cardiac Remodeling, and Renal Injury in Deoxycorticosterone Acetate-Salt Hypertensive Rats (2000) (117)
- Identification of tissue kallikrein in brain and in the cell-free translation product encoded by brain mRNA. (1983) (116)
- Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. (2006) (114)
- Prostasin Is a Glycosylphosphatidylinositol-anchored Active Serine Protease* (2001) (113)
- Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis. (2006) (112)
- Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene (2000) (111)
- Kallikrein/Kinin Protects against Myocardial Apoptosis after Ischemia/Reperfusion via Akt-Glycogen Synthase Kinase-3 and Akt-Bad·14-3-3 Signaling Pathways* (2005) (110)
- Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats. (1998) (106)
- Kallikrein Gene Transfer Protects Against Ischemic Stroke by Promoting Glial Cell Migration and Inhibiting Apoptosis (2004) (106)
- Kallikrein–kinin in stroke, cardiovascular and renal disease (2005) (106)
- Kallikrein-modified mesenchymal stem cell implantation provides enhanced protection against acute ischemic kidney injury by inhibiting apoptosis and inflammation. (2008) (106)
- Identification of a new tissue-kallikrein-binding protein. (1986) (104)
- Tissue kallikrein in rat brain and pituitary: regional distribution and estrogen induction in the anterior pituitary. (1987) (103)
- Human Endothelial Nitric Oxide Synthase Gene Delivery Promotes Angiogenesis in a Rat Model of Hindlimb Ischemia (2002) (102)
- Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats. (1998) (96)
- Kallikrein Gene Delivery Improves Cardiac Reserve and Attenuates Remodeling After Myocardial Infarction (2002) (94)
- Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion. (2000) (94)
- Postischemic Brain Injury Is Exacerbated in Mice Lacking the Kinin B2 Receptor (2006) (93)
- Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation. (2005) (92)
- Hypotension in transgenic mice overexpressing human bradykinin B2 receptor. (1997) (92)
- Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor. (1994) (91)
- Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing (2010) (91)
- Human atrial natriuretic peptide gene delivery reduces blood pressure in hypertensive rats. (1995) (90)
- Expression and cellular localization of the kallikrein-kinin system in human ocular tissues. (1996) (88)
- Kallistatin is a potent new vasodilator. (1997) (88)
- Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction. (2005) (87)
- Salutary Effect of Kallistatin in Salt-Induced Renal Injury, Inflammation, and Fibrosis via Antioxidative Stress (2008) (87)
- Prevention of Diabetes-Induced Microangiopathy by Human Tissue Kallikrein Gene Transfer (2002) (85)
- Rescue of Impaired Angiogenesis in Spontaneously Hypertensive Rats by Intramuscular Human Tissue Kallikrein Gene Transfer (2001) (84)
- Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure. (2000) (83)
- Localization and Expression of Tissue Kallikrein and Kallistatin in Human Blood Vessels (1999) (80)
- Adenovirus-Mediated Human Tissue Kallikrein Gene Delivery Induces Angiogenesis in Normoperfused Skeletal Muscle (2000) (79)
- Overexpression of Kinin B1 Receptors Induces Hypertensive Response to Des-Arg9-bradykinin and Susceptibility to Inflammation* (2003) (78)
- Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli. (1993) (77)
- Muscle delivery of human kallikrein gene reduces blood pressure in hypertensive rats. (1995) (76)
- The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction (2006) (75)
- Novel role of kallistatin in protection against myocardial ischemia-reperfusion injury by preventing apoptosis and inflammation. (2006) (74)
- Tissue distribution and kininogen gene expression after acute-phase inflammation. (1988) (74)
- Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats. (2005) (73)
- Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats. (2000) (72)
- Kallistatin reduces vascular senescence and aging by regulating microRNA‐34a‐SIRT1 pathway (2017) (72)
- Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis (2015) (72)
- Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling. (2010) (71)
- Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. (2001) (69)
- Kruppel-like Factor 4 Is a Novel Mediator of Kallistatin in Inhibiting Endothelial Inflammation via Increased Endothelial Nitric-oxide Synthase Expression* (2009) (69)
- Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats. (1997) (68)
- Kallistatin Inhibits Vascular Inflammation by Antagonizing Tumor Necrosis Factor-&agr;-Induced Nuclear Factor &kgr;B Activation (2010) (68)
- Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats. (1998) (68)
- A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. (2001) (67)
- Adrenomedullin gene delivery protects against cerebral ischemic injury by promoting astrocyte migration and survival. (2004) (67)
- Kinin Infusion Prevents Renal Inflammation, Apoptosis, and Fibrosis via Inhibition of Oxidative Stress and Mitogen-Activated Protein Kinase Activity (2007) (66)
- Kallistatin inhibits TGF-β-induced endothelial-mesenchymal transition by differential regulation of microRNA-21 and eNOS expression. (2015) (66)
- Kallikrein Multigene Families and the Regulation of Their Expression (1990) (66)
- Molecular cloning and expression of rat bradykinin B1 receptor. (1998) (65)
- A common nomenclature for members of the tissue (glandular) kallikrein gene families. (1992) (65)
- Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress. (2004) (65)
- Biochemistry, regulation and potential function of kallistatin. (1995) (64)
- Tissue Kallikrein Elicits Cardioprotection by Direct Kinin B2 Receptor Activation Independent of Kinin Formation (2008) (62)
- Adrenomedullin improves cardiac function and prevents renal damage in streptozotocin-induced diabetic rats. (2002) (62)
- A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor. (2010) (60)
- Effects of diabetes and insulin on expression of kallikrein and renin genes in the kidney. (1992) (59)
- Novel Roles of Kallistatin, a Specific Tissue Kallikrein Inhibitor, in Vascular Remodeling (2001) (59)
- Cellular localization of tissue kallikrein and kallistatin mRNAs in human kidney. (1995) (59)
- Structural elements of kallistatin required for inhibition of angiogenesis. (2003) (58)
- Identification of a Major Heparin-binding Site in Kallistatin* (2001) (58)
- Reversal of renal fibrosis, inflammation, and glomerular hypertrophy by kallikrein gene delivery. (2006) (58)
- Structure and chromosomal localization of the human prostasin (PRSS8) gene. (1996) (58)
- Gene Therapy With Human Tissue Kallikrein Reduces Hypertension and Hyperinsulinemia in Fructose-Induced Hypertensive Rats (2003) (57)
- Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarction (2008) (57)
- Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty. (1999) (57)
- Intermedin is a new angiogenic growth factor. (2009) (55)
- Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway. (2008) (55)
- Immunological identification of rat tissue kallikrein cDNA and characterization of the kallikrein gene family. (1986) (53)
- Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis (2006) (53)
- Restriction fragment length polymorphisms mapped in spontaneously hypertensive rats using kallikrein probes. (1989) (52)
- Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation. (2007) (51)
- Intramuscular Delivery of Rat Kallikrein-binding Protein Gene Reverses Hypotension in Transgenic Mice Expressing Human Tissue Kallikrein (*) (1995) (51)
- Adenovirus-mediated delivery of human kallistatin gene reduces blood pressure of spontaneously hypertensive rats. (1997) (51)
- Tissue kallikrein infusion prevents cardiomyocyte apoptosis, inflammation and ventricular remodeling after myocardial infarction (2007) (50)
- Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury. (2008) (50)
- Bradykinin B(1) receptor mediates inhibition of neointima formation in rat artery after balloon angioplasty. (2000) (50)
- Adenovirus-mediated kallikrein gene delivery reverses salt-induced renal injury in Dahl salt-sensitive rats. (1998) (50)
- Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury (2001) (49)
- Association of the tissue kallikrein gene promoter with ESRD and hypertension. (2002) (49)
- Protective Role of Kallistatin in Vascular and Organ Injury (2016) (48)
- Differential regulation of kininogen gene expression by estrogen and progesterone in vivo. (1992) (48)
- Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection. (2008) (47)
- Genomic DNA sequence, expression, and chromosomal localization of the human B1 bradykinin receptor gene BDKRB1. (1996) (47)
- Molecular cloning and analysis of the rat kallikrein-binding protein gene. (1991) (46)
- Recombinant adeno-associated virus-mediated kallikrein gene therapy reduces hypertension and attenuates its cardiovascular injuries (2004) (46)
- Kallikrein gene delivery attenuates cardiac remodeling and promotes neovascularization in spontaneously hypertensive rats. (2003) (46)
- Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic rats. (1997) (45)
- Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats. (1998) (45)
- Immunocytochemical localization of tissue kallikrein in brain ventricular epithelium and hypothalamic cell bodies. (1985) (45)
- Cloning, sequence analysis and expression of the gene encoding the mouse bradykinin B2 receptor. (1994) (45)
- Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis. (2016) (45)
- Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways. (2007) (45)
- Systemic and portal vein delivery of human kallikrein gene reduces blood pressure in hypertensive rats. (1996) (44)
- Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis (2014) (44)
- Atrial natriuretic peptide gene delivery reduces stroke-induced mortality rate in Dahl salt-sensitive rats. (1999) (44)
- Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling (2007) (42)
- Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6 (2013) (42)
- Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. (2008) (42)
- Pivotal role of JNK-dependent FOXO1 activation in downregulation of kallistatin expression by oxidative stress. (2010) (42)
- Kallistatin in human ocular tissues: reduced levels in vitreous fluids from patients with diabetic retinopathy. (1996) (42)
- Roles of the P1, P2, and P3 Residues in Determining Inhibitory Specificity of Kallistatin toward Human Tissue Kallikrein* (2000) (42)
- Intermedin ameliorates vascular and renal injury by inhibition of oxidative stress. (2008) (41)
- Gene therapy in hypertension: adenovirus-mediated kallikrein gene delivery in hypertensive rats. (1997) (41)
- Enhanced renal function in bradykinin B(2) receptor transgenic mice. (2000) (41)
- Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats. (1999) (41)
- In vivo catabolism of human kallikrein-binding protein and its complex with tissue kallikrein. (1992) (41)
- A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats. (1988) (40)
- Special antigens on sperm from autoimmune infertile men. (1988) (40)
- Molecular cloning, purification and in situ localization of human colon kallikrein. (1995) (40)
- The bradykinin B1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats (1999) (40)
- Renal kallikrein mRNA localization by in situ hybridization. (1989) (40)
- Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling. (2012) (39)
- Adenovirus-mediated kallikrein gene delivery attenuates hypertension and protects against renal injury in deoxycorticosterone-salt rats. (1999) (38)
- Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shock. (1997) (37)
- Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation (2018) (37)
- Molecular cloning and characterization of two rat renal kallikrein genes. (1988) (37)
- Kallistatin Modulates Immune Cells and Confers Anti-Inflammatory Response To Protect Mice from Group A Streptococcal Infection (2013) (37)
- Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation. (2006) (37)
- Plasma kallistatin levels in patients with severe community-acquired pneumonia (2013) (36)
- Experimental therapy with tissue kallikrein against cerebral ischemia. (2006) (36)
- Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway (2010) (36)
- Sex dimorphism and hormonal regulation of rat tissue kallikrein mRNA. (1986) (35)
- Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR. (1999) (34)
- Reactive-site specificity of human kallistatin toward tissue kallikrein probed by site-directed mutagenesis. (2000) (34)
- DNA polymorphisms in the 5′-flanking region of the human tissue kallikrein gene (1997) (34)
- Inhibition of experimental lung metastasis by systemic lentiviral delivery of kallistatin (2010) (34)
- Molecular cloning and primary structure of rat alpha 1-antitrypsin. (1990) (33)
- Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction. (2007) (33)
- Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis (2015) (32)
- Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats. (2003) (32)
- Adenovirus-mediated human tissue kallikrein gene delivery inhibits neointima formation induced by interruption of blood flow in mice. (2000) (32)
- Reversal of Angiogenic Growth Factor Upregulation by Revascularization of Lower Limb Ischemia (2002) (31)
- Functional analysis of human tissue kallikrein in transgenic mouse models. (1996) (31)
- Tissue Kallikrein-binding Protein Reduces Blood Pressure in Transgenic Mice* (1996) (31)
- An unusual interaction between the target of nalidixic acid and novobiocin (1978) (30)
- Identification and characterization of a tissue kallikrein in rat skeletal muscles. (1987) (30)
- Kallistatin stimulates vascular smooth muscle cell proliferation and migration in vitro and neointima formation in balloon-injured rat artery. (2000) (30)
- Role of the bradykinin B2 receptor in the maturation of blood pressure phenotype: lesson from transgenic and knockout mice. (1999) (30)
- Novel Role of Kallistatin in Vascular Repair by Promoting Mobility, Viability, and Function of Endothelial Progenitor Cells (2014) (30)
- Kallikrein-kinin system in inflammatory bowel diseases: Intestinal involvement and correlation with the degree of tissue inflammation. (2005) (30)
- High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. (1996) (30)
- Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats. (2005) (29)
- Molecular cloning, sequence analysis, and chromosomal localization of the human protease inhibitor 4 (kallistatin) gene (PI4). (1994) (29)
- Differential interactions of human kallikrein-binding protein and alpha 1-antitrypsin with human tissue kallikrein. (1990) (29)
- Cellular localization of low-molecular-weight kininogen and bradykinin B2 receptor mRNAs in human kidney. (1996) (29)
- Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation. (2009) (28)
- Ribonucleotides Covalently Linked to Deoxyribonucleic Acid in T4 Bacteriophage (1972) (27)
- High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats. (1996) (27)
- Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands (1998) (27)
- Tissue kallikrein promotes cardiac neovascularization by enhancing endothelial progenitor cell functional capacity. (2012) (26)
- Isolation of tissue kallikrein in rat spleen by monoclonal antibody-affinity chromatography. (1984) (26)
- Experimental kallikrein gene therapy in hypertension, cardiovascular and renal diseases. (1997) (26)
- Tissue kallikrein and kinin infusion promotes neovascularization in limb ischemia (2008) (25)
- Relationship between the regulatory region polymorphism of human tissue kallikrein gene and essential hypertension (2005) (24)
- Identification and expression of kallikrein gene family in rat submandibular and prostate glands using monoclonal antibodies as specific probes. (1987) (24)
- Plasma kallistatin is associated with adiposity and cardiometabolic risk in apparently healthy African American adolescents. (2013) (23)
- A Positively Charged Loop on the Surface of Kallistatin Functions to Enhance Tissue Kallikrein Inhibition by Acting as a Secondary Binding Site for Kallikrein* (2000) (23)
- Circulating Tissue Kallikrein Levels Correlate With Severity of Carotid Atherosclerosis (2004) (22)
- Molecular cloning and sequence analysis of rat bradykinin B2 receptor gene. (1994) (22)
- Specificity of human tissue kallikrein towards substrates containing Phe-Phe pair of amino acids. (1999) (22)
- Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation. (2010) (22)
- Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension. (1992) (21)
- Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues. (1994) (21)
- Tissue Kallikrein-Modified Human Endothelial Progenitor Cell Implantation Improves Cardiac Function via Enhanced Activation of Akt and Increased Angiogenesis (2013) (21)
- Age and hormonal dependence of tonin levels in rat submandibular gland as determined by a new direct radioimmunoassay. (1986) (21)
- Differential regulation of kallikrein, kininogen, and kallikrein-binding protein in arterial hypertensive rats. (1996) (21)
- Bradykinin B1 Receptor Mediates Inhibition of Neointima Formation in Rat Artery After Balloon Angioplasty (2000) (20)
- Methods in Nucleic Acids Research (1990) (20)
- Upregulation of kallistatin expression in rheumatoid joints. (2007) (20)
- Characterization of genes encoding rat tonin and a kallikrein-like serine protease. (1989) (20)
- Adrenomedullin gene delivery inhibits neointima formation in rat artery after balloon angioplasty (2003) (20)
- Kallistatin attenuates endothelial senescence by modulating Let‐7g‐mediated miR‐34a‐SIRT1‐eNOS pathway (2018) (20)
- Participation of kinins in the captopril‐induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse (2000) (19)
- Human tissue kallikrein attenuates hypertension and secretes into circulation and urine after intramuscular gene delivery in hypertensive rats. (1999) (19)
- Atrial natriuretic peptide gene delivery attenuates gentamycin-induced nephrotoxicity in rats. (1999) (18)
- Characterization of monoclonal and polyclonal antibodies to human tissue kallikrein. (1985) (18)
- Expression of human tissue kallikrein in rat salivary glands and its secretion into circulation following adenovirus-mediated gene transfer. (1997) (18)
- The Role of Adrenomedullin in Cardiovascular and Renal Function. (2002) (18)
- Kallistatin Ameliorates Influenza Virus Pathogenesis by Inhibition of Kallikrein-Related Peptidase 1-Mediated Cleavage of Viral Hemagglutinin (2015) (18)
- Specific identification of tissue kallikrein in exocrine tissues and in cell-free translation products with monoclonal antibodies. (1985) (18)
- Adenovirus-mediated kallikrein gene transfer inhibits neointima formation via increased production of nitric oxide in rat artery. (1999) (18)
- Antisense inhibition of the brain kallikrein-kinin system. (1996) (18)
- Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression (2017) (17)
- Central delivery of human tissue kallikrein gene reduces blood pressure in hypertensive rats. (1998) (17)
- Tissue kallikrein-modified mesenchymal stem cells provide enhanced protection against ischemic cardiac injury after myocardial infarction. (2013) (17)
- Expression and cellular localization of tissue kallikrein-kinin system in human adrenal gland. (1996) (17)
- Molecular cloning and sequence analysis of the monkey and human tissue kallikrein genes. (1993) (16)
- Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene. (1991) (16)
- Kallistatin suppresses cancer development by multi-factorial actions. (2017) (16)
- Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice (2018) (15)
- Sex dimorphism and inflammatory regulation of T-kininogen and T-kininogenase. (1989) (15)
- Purification and characterization of recombinant tissue kallikrein from Escherichia coli and yeast. (1991) (15)
- The bradykinin B 1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats (1999) (15)
- Kallistatin: double-edged role in angiogenesis, apoptosis and oxidative stress (2017) (15)
- Biochemical characterization and substrate specificity of rat prostate kallikrein (S3): comparison with tissue kallikrein, tonin and T-kininogenase. (1992) (15)
- Tissue kallikrein inhibitors in mammals. (1996) (15)
- Plasma kallistatin in critically ill patients with severe sepsis and septic shock (2017) (15)
- Kallikrein gene therapy: a new strategy for hypertensive diseases. (1997) (14)
- Identification of latent tissue kallikrein, prolactin and growth hormone secretion in GH3 pituitary cells using modified radioimmunoassays (1988) (14)
- Distribution of tissue kallikreins in lower vertebrates: potential physiological roles for fish kallikreins. (1997) (14)
- Co-localization of a kallikrein-like serine protease (arginine esterase A) and atrial natriuretic peptide in rat atrium. (1989) (13)
- High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice. (1996) (13)
- Kallikrein gene therapy in hypertension , cardiovascular and renal diseases (2001) (13)
- Sperm and seminal plasma antigens from autoimmune men induce immunological infertility. (1987) (13)
- Regulation of Kininogen Gene Expression and Localization in the Lung after Monocrotaline-Induced Pulmonary Hypertension in Rats (1993) (13)
- Kallikrein gene therapy in newborn and adult hypertensive rats. (1997) (12)
- Molecular cloning and characterization of rKlk10, a cDNA encoding T-kininogenase from rat submandibular gland and kidney. (1992) (12)
- Bacteriophage T4 head morphogenesis: host DNA enzymes affect frequency of petite forms. (1974) (12)
- Opposing Effects of Oxygen Regulation on Kallistatin Expression: Kallistatin as a Novel Mediator of Oxygen-Induced HIF-1-eNOS-NO Pathway (2017) (12)
- Identification of a kallikrein-like latent serine protease in human erythrocyte membranes. (1984) (12)
- Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat. (1997) (11)
- Purification and characterization of tissue kallikrein-like proteinases from the black sea bass (Centropristis striata) and the southern frog (Rana berlandieri). (1995) (10)
- The purification of human urinary kallikrein with ion-exchange radial flow membrane chromatography. (1996) (10)
- An improved method for the measurement of rat tissue kallikrein using a monoclonal antibody which recognizes only active enzyme. (1986) (10)
- Kallistatin in blood pressure regulation transgenic and somatic gene delivery studies. (1997) (9)
- Human kallistatin, a new tissue kallikrein-binding protein: purification and characterization. (1989) (9)
- Purification, characterization and activation of fish muscle prokallikrein. (1997) (9)
- Identification of tonin in brain and exocrine tissues and in the cell-free translation products encoded by the mRNA of these tissues. (1987) (8)
- Immunocytochemical localization of a kallikrein‐like serin protease (Esterase A) in rat salivary glands (1988) (8)
- Expression and characterization of rat kallikrein-binding protein in Escherichia coli. (1993) (8)
- Molecular cloning and expression of rat kallistatin gene. (1997) (8)
- Tissue kallikrein-kinin therapy in hypertension and organ damage. (2014) (8)
- Purification and characterization of salivary kallikrein from an insectivore (Scalopus aquaticus): substrate specificities, immunoreactivity, and kinetic analyses. (1996) (7)
- Enhanced specificity in immunoscreening of expression cDNA clones using radiolabeled antigen overlay. (1989) (7)
- Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats. (1995) (7)
- Histopathology of lymphatic tissues in transgenic mice expressing human tissue kallikrein gene. (1994) (7)
- Specificity determinants of rat tissue kallikrein probed by site-directed mutagenesis. (1992) (7)
- Cellular localization of bradykinin B1 receptor mRNA in the human kidney. (1996) (7)
- Localization of kallikrein gene family proteases in rat tissues. (1992) (6)
- Expression and localization of human kallistatin in rat submandibular gland after intracapsular gene injection. (1997) (6)
- New experimental evidence for a role of tissue kallikrein in hypertension. (1997) (6)
- Kallikrein-kinin in stem cell therapy. (2014) (6)
- Identification and characterization of two promoters of rat kallikrein-binding protein gene. (1996) (6)
- Tissue kallikrein is related to the severity of coronary artery disease. (2013) (6)
- The inhibition of f2 RNA directed E. coli protein synthesis by poly rI-rC in vitro. (1971) (6)
- Urinary Levels of Kallikrein and Kallistatin in Pregnancy-Induced Hypertension (1995) (5)
- Immunological analysis of rat pancreatic prokallikrein activation. (1985) (5)
- Evolution of the kallikrein gene family. (1992) (4)
- Active kallikrein, preprokallikrein, and kallikrein-inhibitor complex. (1986) (4)
- Comparison of the distribution of tissue kallikrein and esterase A, a kallikrein-like enzyme, in rat kidney using specific monoclonal antibodies. (1988) (4)
- A simple procedure for high efficiency counting of labeled protein bands in polyacrylamide slab gels (1981) (4)
- Kallikrein‐binding protein is induced by growth hormone in the dwarf rat (1999) (4)
- Tissue-specific expression and promoter analyses of the human tissue kallikrein gene in transgenic mice. (1997) (4)
- [12] Rat urinary kallikrein (1988) (3)
- Characterization of rat kallikrein-like multigene family and its expression in the submandibular gland. (1986) (3)
- Tissue kallikreins in evolutionarily diverse vertebrates. (1996) (3)
- Circulating Autoantibodies to Mammalian Tissue Kallikreins 1 (1988) (3)
- Tissue Kallikrein Reverses Insulin Resistance and Attenuates Nephropathy in Diabetic Rats by Activation of PI3 kinase/Akt and AMPK Signaling Pathways (2013) (3)
- Structural analysis of a rat renal kallikrein gene. (1989) (3)
- A monoclonal antibody to rat tissue kallikrein: use in biochemical and immunohistochemical studies. (1986) (3)
- Altered stability and integration frequency of a F′ factor in RNA polymerase mutants of Escherichia coli (2004) (3)
- Expression of the Thy-1 gene in human T lymphoid cell lines. (1988) (3)
- Austin Biomarkers & Diagnosis Kallistatin: A Novel Biomarker for Hypertension, Organ Injury and Cancer (2015) (3)
- Response to Deficiency of Bradykinin Receptor B2 Is not Detrimental in Experimental Stroke (2008) (3)
- Sex dimorphism and estrogen regulation of kininogens in rat serum, adrenal gland and kidney. (1989) (2)
- Encapsulated transgene cells attenuate hypertension, cardiac hypertrophy and enhance renal function in Goldblatt hypertensive rats (2004) (2)
- Comparative studies on P2 specificity of wild-type rat tissue kallikrein, Y99H:W215G mutant and tonin. (1992) (2)
- Rat urinary kallikrein. (1988) (2)
- G11 – Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats (1995) (1)
- Kallikrein localization in rat brain by immunohistochemistry. (1986) (1)
- Role of the brain kallikrein-kinin system in the pathogenesis of genetic hypertension (1995) (1)
- Adenovirus-Mediated Delivery of Human Tissue Kallikrein Gene Reduces Blood Pressure in Goldblatt-Hypertensive Rats (1998) (1)
- Gene therapy for hypertension: a review of potential targets. (1999) (1)
- Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6 (2013) (1)
- Kallikrein Gene Transfer in Hypertension, Cardiovascular and Renal Disease, and Stroke (2005) (1)
- Gene Therapy for Hypertension (2012) (1)
- Adenovirus-mediated gene transfer for cardiovascular and renal diseases. (2002) (1)
- The Kallikrein-Kinin System and Hypertension (2007) (1)
- 果糖诱导大鼠胰岛素抵抗和高血压的机制及人组织型激肽释放酶基因的治疗作用 (2003) (0)
- the bradykinin B1-receptor partecipates in the central regulation of blood pressure in spontaneously hypertensive rats (1998) (0)
- Activation of Akt-GSK Signaling Adrenomedullin Protects Against Myocardial Apoptosis After Ischemia / Reperfusion (2003) (0)
- Human Tissue Kallikrein Gene Transfer Accelerates Spontaneous Angiogenesis Response to Ischemia (2000) (0)
- Tissue kallikrein gene therapy reduces blood pressure in spontaneously hypertensive rats (1994) (0)
- Kallistatinin Blood Pressure Regulation Transgenicand Somatic Gene DeliveryStudies (1997) (0)
- Differential interactions of human kallikrein-binding protein and ;,-antitrypsin with human tissue kallikrein (2005) (0)
- Corrigendum (2000) (0)
- Basic Science and Experimental Studies Tissue Kallikrein and Kinin Infusion Rescues Failing Myocardium After Myocardial Infarction (2007) (0)
- Kallistatin in Sepsis: Protective Actions and Potential Therapeutic Applications (2017) (0)
- Experimental Approaches Using Kallikrein Gene Therapy for Hypertension (1997) (0)
- Alterations in blood pressure control and cardiac pathophysiology in human tissue kallikrein transgenic fats (1998) (0)
- Human Tissue Kallikrein Gene Delivery Attenuates Cardiac Glycogen Accumulation in Streptozotocin-Induced Diabetic Rats (2000) (0)
- Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat. (1997) (0)
- Human Tissue Kallikrein Gene Transfer Rescue of Impaired Angiogenesis in Spontaneously Hypertensive Rats by Intramuscular (2001) (0)
- Rapid Publication Kallistatin Is a Potent New Vasodilator (2013) (0)
- Adrenomedullin Gene Delivery Reduces in Spontaneously Hypertensive Blood Rats Pressure (2006) (0)
- Central delivery of genes encoding for human tissue kallikrein or atrial natriuretic peptide reduces blood pressure in spontaneously hypertensive rats. (1998) (0)
- Role of the kallikrein kinin system in gestational hypertension. (1994) (0)
- hypertensive rats and promotes neovascularization in spontaneously Kallikrein gene delivery attenuates cardiac remodeling (2016) (0)
- Human Tissue Kallikrein Gene Transfer Induces Angiogenesis (2000) (0)
- Results Effects of Tissue Kallikrein and B 1 and B 2 Receptor Antagonists on the Proliferation of Primary Cultured VSMCs (2000) (0)
- SPERM AND SEMINAL PLASMA ANTIGENS IMMUNOLOGICAL INFERTILITY FROM AUTOIMMUNE MEN rmum (1987) (0)
- Lentivirus-mediated kallistatin gene transfer for the treatment of metastatic lung cancer (2008) (0)
- Erratum: Adenovirus-mediated human tissue kallikrein gene delivery inhibits neontima formation induced by interruption of blood flow in mice (Arteriosclerosis, Thrombosis, and Vascular Biology (June 2000) (1459-1466)) (2000) (0)
- [25] – Screening of Complementary DNA Library Using Radiolabeled Antigen (1995) (0)
- is a new inhibitor of angiogenesis and tumor growth (2002) (0)
- Pleiotropic Effects of Kallikrein-Kinin on Apoptosis, Inflammation and Angiogenesis in Cardiovascular Disease and Stroke (2003) (0)
- Screening of complementary DNA library using radiolabeled antigen. (1993) (0)
- Adenovirus-Mediated Human Kallikrein Gene Delivery Increases Endogenous Rat Tissue Kallikrein in Hypertensive Rat Models (2000) (0)
- Kallistatin Inhibits Endothelial Cell Proliferation, Migration and Adhesion in Vitro and Angiogenesis in the Ischemic Hindlimb of Rats (2000) (0)
- Kallikrein Gene Delivery Attenuates Cardiac Remodeling after Myocardial Infarction through the Inhibition of Cardiac Apoptosis (2002) (0)
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