Lawrence Hadley Thompson

Lawrence Hadley Thompson's AcademicInfluence.com Rankings

Biology

#10433

World Rank

#13763

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Genetics

#1101

World Rank

#1200

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Molecular Biology

#1515

World Rank

#1542

Historical Rank

Biochemistry

#1643

World Rank

#1778

Historical Rank

biology Degrees

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Biology

Lawrence Hadley Thompson's Degrees

PhD Molecular Biology University of California, Berkeley
Masters Biochemistry Stanford University

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Lawrence Hadley Thompson's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. (1999) (1308)
Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle (2003) (1221)
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. (1998) (580)
An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III (1994) (508)
XRCC1 keeps DNA from getting stranded. (2000) (486)
Recombinational DNA repair and human disease. (2002) (460)
Homologous recombinational repair of DNA ensures mammalian chromosome stability. (2001) (454)
Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange (1990) (408)
Ouabain-resistant mutants of mouse and hamster cells in culture (1974) (385)
Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. (1999) (350)
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography. (2012) (345)
A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange. (1982) (340)
Human xeroderma pigmentosum group D gene encodes a DMA helicase (1993) (314)
Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells. (1995) (304)
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. (1995) (280)
Molecular mechanisms of sister-chromatid exchange. (2007) (258)
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3. (1990) (250)
Life without DNA repair. (1997) (234)
Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents. (1985) (229)
Chapter 7: Isolation of Mutants of Cultured Mammalian Cells (1973) (184)
Reconstitution of Human Excision Nuclease with Recombinant XPF-ERCC1 Complex* (1997) (183)
Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells (1988) (178)
Proliferation kinetics of x-irradiated mouse L cells studied WITH TIME-lapse photography. II. (1969) (178)
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. (2003) (170)
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights. (2009) (167)
Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells. (1981) (156)
Fanconi Anemia Protein FANCD2 Promotes Immunoglobulin Gene Conversion and DNA Repair through a Mechanism Related to Homologous Recombination (2005) (147)
A mammalian cell mutant with a temperature-sensitive leucyl-transfer RNA synthetase. (1973) (145)
Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells (2001) (145)
Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair. (1998) (144)
The contribution of homologous recombination in preserving genome integrity in mammalian cells. (1999) (141)
Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells. (1980) (141)
Identification of a novel human RAD51 homolog, RAD51B. (1997) (139)
Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. (2002) (139)
DNA crosslinking, sister-chromatid exchange and specific-locus mutations. (1979) (138)
Fanconi Anemia FANCG Protein in Mitigating Radiation- and Enzyme-Induced DNA Double-Strand Breaks by Homologous Recombination in Vertebrate Cells (2003) (132)
Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. (2002) (127)
ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs (1996) (125)
Genomic sequence comparison of the human and mouse XRCC1 DNA repair gene regions. (1995) (121)
Defects in the DNA repair and transcription gene ERCC2 in the cancer-prone disorder xeroderma pigmentosum group D. (1995) (113)
Defects in the DNA repair and transcription gene ERCC2(XPD) in trichothiodystrophy. (1996) (111)
Molecular cloning of the human DNA excision repair gene ERCC-6 (1990) (110)
Evidence that mammalian cells possess homologous recombinational repair pathways. (1996) (108)
Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells. (2005) (107)
How Fanconi anemia proteins promote the four Rs: Replication, recombination, repair, and recovery (2005) (107)
Isolation of temperature-sensitive mutants of L-cells. (1970) (104)
A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges. (1992) (103)
Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster cells. (1982) (103)
Refined mapping of the three DNA repair genes, ERCC1, ERCC2, and XRCC1, on human chromosome 19. (1989) (102)
FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 (2008) (97)
Rare microsatellite polymorphisms in the DNA repair genesXRCC1, XRCC3 andXRCC5 associated with cancer in patients of varying radiosensitivity (1997) (92)
Repression of mutagenesis by Rad51D-mediated homologous recombination (2006) (90)
The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells. (1997) (87)
Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening. (1989) (86)
CHO mutant UV61 removes (6-4) photoproducts but not cyclobutane dimers. (1989) (83)
Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells. (1990) (80)
Unraveling the Fanconi anemia–DNA repair connection (2005) (79)
Human creatine kinase genes on chromosomes 15 and 19, and proximity of the gene for the muscle form to the genes for apolipoprotein C2 and excision repair. (1988) (78)
Nomenclature of human genes involved in ionizing radiation sensitivity. (1995) (78)
Recent Progress with the DNA Repair Mutants of Chinese Hamster Ovary Cells (1986) (76)
Correction of a nucleotide-excision-repair mutation by human chromosome 19 in hamster-human hybrid cells (1985) (75)
Complementation of repair gene mutations on the hemizygous chromosome 9 in CHO: a third repair gene on human chromosome 19. (1989) (74)
Measurement of sister chromatid exchanges at very low bromodeoxyuridine substitution levels using a monoclonal antibody in Chinese hamster ovary cells. (1985) (74)
Assignment of a human DNA-repair gene associated with sister-chromatid exchange to chromosome 19. (1986) (71)
Excision repair in man and the molecular basis of xeroderma pigmentosum syndrome. (1993) (68)
Rescue of Xrcc1 knockout mouse embryo lethality by transgene-complementation. (2003) (68)
CHO cell mutants for arginyl-, asparagyl-, glutaminyl-, histidyl- and methionyl-transfer RNA synthetases: Identification and initial characterization (1977) (67)
The relationship between sister-chromatid exchange and perturbations in DNA replication in mutant EM9 and normal CHO cells. (1983) (64)
Selection by [3H] amino acids of CHO-cell mutants with altered leucyl- and asparagyl-transfer RNA synthetases (1975) (63)
Rapid detection of DNA-damaging agents using repair-deficient CHO cells. (1984) (63)
Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A (2009) (62)
New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant. (2005) (61)
An eighth complementation group of rodent cells hypersensitive to ultraviolet radiation (1988) (57)
Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination (2006) (56)
Somatic cell genetics approach to dissecting mammalian DNA repair (1989) (56)
Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. (2006) (55)
The Fanconi anemia pathway limits the severity of mutagenesis. (2006) (55)
Isolation of mutants of cultured mammalian cells. (1973) (55)
Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells. (1980) (54)
Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis. (2009) (54)
Identification of nucleotide-excision-repair genes on human chromosomes 2 and 13 by functional complementation in hamster-human hybrids (1987) (53)
DNA-strand breaks associated with halogenated pyrimidine incorporation. (1984) (53)
Testis and somaticXrcc-1 DNA repair gene expression (1994) (50)
Recombination and ligation of transfected DNA in CHO mutant EM9, which has high levels of sister chromatid exchange (1987) (50)
Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line. (1986) (49)
Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation. (2010) (49)
Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1. (1991) (48)
Analysis of mammalian-cell mutagenesis and DNA repair using in-vitro selected CHO cell mutants (1983) (47)
Proliferation kinetics of x-irradiated mouse L cells studied with time-lapse photography. I. Experimental methods and data analysis. (1967) (45)
Repair of (6-4)photoproducts correlates with split-dose recovery in UV-irradiated normal and hypersensitive rodent cells. (1988) (44)
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives. (1989) (44)
Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in culture (1982) (44)
Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9. (1992) (44)
DNA-mediated transfer of a human DNA repair gene that controls sister chromatid exchange (1985) (44)
Genetic complementation between UV-sensitive CHO mutants and xeroderma pigmentosum fibroblasts. (1985) (43)
The localization of the human myeloperoxidase gene is in close proximity to the translocation breakpoint in acute promyelocytic leukemia. (1987) (43)
Molecular cloning of the human nucleotide-excision-repair gene ERCC4. (1994) (43)
FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ (2011) (42)
Properties and applications of human DNA repair genes. (1991) (42)
Alterations in expression and structure of the DNA repair gene XRCC1. (1992) (41)
Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity. (1997) (38)
Conserved domains in the chicken homologue of BRCA2 (2002) (37)
Nomenclature of human DNA repair genes. (1994) (36)
Nucleotide Excision Repair (1998) (36)
DNA-ligase activities appear normal in the CHO mutant EM9. (1984) (36)
Role of DNA repair in mutagenesis of Chinese hamster ovary cells by 7-bromomethylbenz[a]anthracene. (1982) (36)
Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2. (1991) (34)
A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity. (1996) (34)
Hypersensitivity to cell killing and mutation induction by chemical carcinogens in an excision repair-deficient mutant of CHO cells. (1983) (34)
Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants. (1988) (34)
DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135 (1984) (33)
Low doses of alpha particles do not induce sister chromatid exchanges in bystander Chinese hamster cells defective in homologous recombination. (2007) (32)
XRCC3 ATPase Activity Is Required for Normal XRCC3-Rad51C Complex Dynamics and Homologous Recombination* (2004) (32)
Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4. (1997) (31)
Assignment of the XRCC2 human DNA repair gene to chromosome 7q36 by complementation analysis. (1995) (31)
Repair pathways independent of the Fanconi anemia nuclear core complex play a predominant role in mitigating formaldehyde-induced DNA damage. (2011) (31)
A CHO-cell mutant with a defect in cytokinesis (1976) (30)
Poly(ADP-ribose) metabolism appears normal in EM9, a mutagen-sensitive mutant of CHO cells. (1984) (29)
Proliferation kinetics of mouse L-P59 cells irradiated with ultraviolet light: a time-lapse photographic study. (1970) (28)
Clonal variation in colony morphology and growth of CHO cells cultured on agar (1977) (27)
Homologous recombination repair protects against particulate chromate-induced chromosome instability in Chinese hamster cells. (2007) (26)
A yeast DNA repair gene partially complements defective excision repair in mammalian cells. (1988) (25)
Cyclobutane-pyrimidine dimer excision in UV-sensitive CHO mutants and the effect of the human ERCC2 repair gene. (1990) (24)
UV mutagenesis, cytotoxicity and split-dose recovery in a human-CHO cell hybrid having intermediate (6-4) photoproduct repair. (1989) (24)
Regional mapping of human DNA excision repair gene ERCC4 to chromosome 16p13.13-p13.2. (1993) (24)
Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis (2007) (24)
Sister chromatid exchange and gene mutation. (1982) (23)
Characterization of revertants of the CHO EM9 mutant arising during DNA transfection. (1991) (22)
Comparative mutagenic efficiencies of the DNA adducts from the cooked-food-related mutagens Trp-P-2 and IQ in CHO cells. (1985) (22)
Influence of homologous recombinational repair on cell survival and chromosomal aberration induction during the cell cycle in gamma-irradiated CHO cells. (2010) (22)
Nucleotide Excision Repair: Its Relation to Human Disease (1998) (22)
Complementation group assignments of moderately UV-sensitive CHO mutants isolated by large-scale screening (FAECB). (1994) (22)
The nature of conditionally lethal temperature‐sensitive mutations in somatic cells (1978) (21)
Chinese hamster cells meet DNA repair: an entirely acceptable affair. (1998) (21)
Apurinic/apyrimidinic endonuclease activities appear normal in the CHO-cell ethyl methanesulfonate-sensitive mutant, EM9. (1984) (21)
Isolation and characterization of mouse Xrcc-1, a DNA repair gene affecting ligation. (1994) (21)
[3H]Amino acid selection of aminoacyl-tRNA synthetase mutants of CHO cells: Evidence of homo- vs. hemizygosity at specific loci (1979) (20)
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines. (1992) (20)
Sequence Conversion by Single Strand Oligonucleotide Donors via Non-homologous End Joining in Mammalian Cells* (2010) (19)
Myogenin is in an evolutionarily conserved linkage group on human chromosome 1q31-q41 and unlinked to other mapped muscle regulatory factor genes. (1990) (17)
Genetic regulation of membrane function in mammalian cells in culture. (1973) (16)
Origin, Recognition, Signaling and Repair of DNA Double-Strand Breaks in Mammalian Cells (2013) (15)
Response of mouse L-P59 cells to x-irradiation in the G2 phase. (1969) (15)
Interactions involving the Rad 51 paralogs Rad 51 C and XRCC 3 in human cells (2002) (13)
Poly (ADP-ribosylation) and DNA topoisomerase I in different cell lines. (1984) (11)
Erratum: Identification of a novel human RAD51 homolog, RAD51B (Genomics (1997) 46:3 (476-479)) (1998) (11)
The human XRCC 9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV 40 cells (1997) (11)
Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3. (2004) (11)
Strategies for cloning mammalian DNA repair genes. (1999) (11)
An informative panel of somatic cell hybrids for physical mapping on human chromosome 19q. (1993) (10)
Efficient repair of 8-oxo-7,8-dihydrodeoxyguanosine in human and hamster xeroderma pigmentosum D cells. (2000) (10)
[26] Mutant isolation (1979) (10)
Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response. (2010) (9)
Mutant isolation. (1979) (9)
Role of the Fancg gene in protecting cells from particulate chromate-induced chromosome instability. (2007) (8)
Restoration of Nucleotide Excision Repair in a Helicase-DeficientXPD Mutant from Intragenic Suppression by a Trichothiodystrophy Mutation (2001) (8)
Isolating human DNA repair genes using rodent-cell mutants (1987) (8)
Newly identified CHO ERCC3/XPB mutations and phenotype characterization. (2010) (7)
Nuclear localization of Rad51B is independent of Rad51C and BRCA2. (2005) (7)
Sister chromatid exchange, DNA repair, and single-gene mutation (1981) (7)
DNA repair genes of mammalian cells. (1986) (7)
Partial Correction of the Single‐Strand Break Repair Defect in the CHO Mutant EM9 by Electroporated Recombinant XRCC1 Protein a (1994) (6)
Human DNA Repair and Recombination Genes (1989) (5)
Using repair-deficient Chinese hamster ovary cells to study mutagenesis (1986) (5)
Codominance associated with overexpression of certain XPD mutations. (2001) (4)
Recent developments with the human repair genes ERCC2, ERCC4, and XRCC1 (1992) (3)
RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells. (2009) (2)
Identifying genes and proteins involved in human DNA repair processes using somatic cell and molecular genetics. (1996) (2)
Correction: FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ (2011) (2)
Molecular Cloning of the Human DNA Excision Repair (2)
Construction of human XRCC 1 minigenes that fully correct the CHO DNA repair mutant EM 9 (2005) (2)
Isolation ofTemperature-Sensitive MutantsofL-Cells* (1970) (1)
Cytogenetic characterization of the CHO mutant EM9 (1983) (1)
Recombination in Vertebrate Cells Double-Strand Breaks by Homologous Radiation-and Enzyme-Induced DNA Fanconi Anemia FANCG Protein in Mitigating (2003) (1)
Recent progress in characterizing human DNA repair genes cloned using rodent cell lines (1991) (1)
Cytogenetic characterization of the Chinese hamster ovary mutant EM9. (1984) (0)
Life without DNA repair ( DNA damage y base excision repair y knockout mutations y transgenic mice ) (1997) (0)
The use of DNA-repair-deficient mutants of Chinese hamster ovary cells in studying mutagenesis mechanisms and testing for environmental mutagens. (1983) (0)
Molecular Cloning and Biological Characterization of a Human Gene, ERCC2, That Corrects the Nucleotide Excision (2003) (0)
Repair Machinery for Radiation-Induced DNA Damage (2002) (0)
Sequence analysis of the APRT gene in PhIP-induced CHO UV5P3 mutants (1994) (0)
P V.2 Comparative sequence analysis of human and rodent DNA repair genes (1997) (0)
Role of Fanconi Anemia FANCG in Preventing Double-Strand Breakage and Chromosomal Rearrangement during DNA Replication (2003) (0)
Dissecting human DNA repair. (1987) (0)
Unraveling the Fanconi anaemia-DNA repair connection through DNA helicase and translocase activities (2005) (0)
Homologous Recombinational Repair The Rad 51 Paralog Rad 51 B Promotes (2000) (0)
S21 05 WA – ANALYSIS OF GENES INVOLVED IN SENSITIVITY TO IONIZING RADIATION (1991) (0)
A somatic cell and molecular genetics approach to DNA repair and mutagenesis. (1986) (0)
PROLIFERATION KINETICS AND CELL SURVIVAL OF X-IRRADIATED MAMMALIAN CELLS IN VITRO (1969) (0)
A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation sensitivity group of mitomycin C (1996) (0)
Are sister chromatid exchanges a measure of single gene mutations (1978) (0)
P25 14 WP – MOLECULAR ANALYSIS OF THE MAMMALIAN XRCC1 DNA REPAIR GENE (1991) (0)
Examination of APRT in presumptive CHO heterozygotes (1981) (0)
Double Strand Break Repair (2004) (0)
Molecular cloning of the human nucleotide-excision-repair gene ERCC 4 ( DNA repi / cl Ne UV 41 / excdnuclease / genefic compemenaon / UV rance ) (0)
Four human FANCG polymorphic variants show normal biological function in hamster CHO cells. (2006) (0)
Cell survival determined by colony formation assay after acute or chronic exposure to MMC (2011) (0)
NOTES DNA-Mediated Transfer ofaHumanDNA Repair GeneThat Controls Sister Chromatid Exchange (1985) (0)
Nuclear localization of Rad 51 B is independent of Rad 51 C and BRCA 2 (2005) (0)
uv excision-repair gene transfer in Chinese hamster ovary (CHO) cells (1983) (0)
Role of DNA repair in mutagenesis by 7-bromomethylbenz(a)anthracer (mutagen sensitivity/mutation induction/sister chromatid exchange/t (2016) (0)
Defective Removal of DMA Cross-Links in a Repair-deficient Mutant of Chinese Hamster Cells1 (2006) (0)
Losing and finding myself in DNA repair. (2012) (0)
Defective DMA Cross-Link Removal in Chinese Hamster Cell Mutants Hypersensitive to Bifunctional Alkylating Agents1 (2006) (0)

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What Schools Are Affiliated With Lawrence Hadley Thompson?

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