Leonard John Deftos
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Medical Philosophy
Leonard John Deftos's Degrees
- Masters Medicine University of California, San Diego
- PhD Pharmacology University of California, San Diego
Why Is Leonard John Deftos Influential?
(Suggest an Edit or Addition)Leonard John Deftos's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- 1,25-dihydroxyvitamin D3 receptors in human leukocytes. (1983) (1046)
- New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease. (1980) (674)
- Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups. (1980) (671)
- Secretion of chromogranin A by peptide-producing endocrine neoplasms. (1986) (463)
- The role of 1 alpha, 25-dihydroxyvitamin D in the mediation of intestinal hyperabsorption of calcium in primary hyperparathyroidism and absorptive hypercalciuria. (1977) (261)
- Chromogranin A: its role in endocrine function and as an endocrine and neuroendocrine tumor marker. (1991) (254)
- Chromogranin A: immunohistology reveals its universal occurrence in normal polypeptide hormone producing endocrine glands. (1983) (233)
- The rate of bone mineral loss in normal men and the effects of calcium and cholecalciferol supplementation. (1990) (232)
- Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas. (1988) (209)
- Influence of age and sex on plasma calcitonin in human beings. (1980) (205)
- The short-term effects of conjugated estrogen on bone turnover in older women. (1994) (203)
- Synthesis of a biologically active N-terminal tetratriacontapeptide of parathyroid hormone. (1971) (189)
- 1,25-Dihydroxyvitamin D3 stimulates the alkaline phosphatase activity of osteoblast-like cells. (1981) (179)
- UNCOUPLING OF BONE FORMATION AND RESORPTION BY COMBINED OESTROGEN AND PROGESTAGEN THERAPY IN POSTMENOPAUSAL OSTEOPOROSIS (1985) (177)
- Immunoreactive human chromogranin A in diverse polypeptide hormone producing human tumors and normal endocrine tissues. (1983) (174)
- Bone mineral density and indexes of bone metabolism in spinal cord injury. (1998) (160)
- 1 alpha,25-Dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production. (1986) (152)
- Parathyroid hormone-related protein: a potential autocrine growth regulator in human prostate cancer cell lines. (1994) (148)
- 1,25-Dihydroxyvitamin D3 receptor-like macromolecule in rat osteogenic sarcoma cell lines. (1980) (132)
- Immunohistochemical localization of parathyroid hormone-related protein in human prostate cancer. (1993) (130)
- Parathyroid hormone: sequence, synthesis, immunoassay studies. (1971) (125)
- Calcitonin secretion in normal human subjects. (1978) (122)
- Relationship of fasting urinary calcium to circulating estrogen and body weight in postmenopausal women. (1980) (121)
- Estrogen replacement therapy: indications and complications. (1983) (116)
- Changes in plasma vitellogenin, sex steroids, calcitonin, and thyroid hormones related to sexual maturation in female brown trout (Salmo trutta). (1989) (112)
- Effects of high calcium intake on blood pressure and calcium metabolism in young SHR. (1984) (112)
- Demonstration by immunoperoxidase histochemistry of calcitonin in the anterior lobe of the rat pituitary. (1978) (110)
- Isolation and characterization of the bovine parathyroid isohormones. (1971) (104)
- Elevated serum chromogranin A concentrations in small-cell lung carcinoma. (1986) (103)
- The effect of electroporation on iontophoretic transdermal delivery of calcium regulating hormones. (2000) (100)
- Immunochemical heterogeneity of calcitonin in plasma. (1975) (100)
- The parathyroid hormone-related protein associated with malignancy is secreted by neuroendocrine tumors. (1989) (97)
- Knockdown of the β1 integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis (2011) (96)
- Parathyroid hormone–related peptide is a naturally occurring, protein kinase A–dependent angiogenesis inhibitor (2002) (96)
- Hormone-negative, chromogranin A-positive endocrine tumors. (1989) (94)
- Immunoassay for human calcitonin. I. Method. (1971) (88)
- The amino acid sequence of porcine thyrocalcitonin. (1968) (87)
- The antiproliferative effect of calcitriol on human peripheral blood mononuclear cells. (1986) (87)
- Parathyroid hormone-like protein is a secretory product of atrial myocytes. (1993) (87)
- Immunoassay and immunohistology studies of chromogranin A as a neuroendocrine marker in patients with carcinoma of the prostate. (1996) (85)
- The cytoreceptor assay for 1,25-dihydroxyvitamin D and its application to clinical studies. (1983) (84)
- Immunoreactive calcitonin in the intermediate lobe of the pituitary gland. (1978) (82)
- Hyperparathyroidism: Gastric Acid Secretion and Gastrin (1972) (81)
- Effects of hypophysectomy and subsequent hormonal replacement therapy on hormonal and osmoregulatory status of coho salmon, Oncorhynchus kisutch. (1987) (81)
- Localization of parathyroid adenomas by selective venous catheterization and radioimmunoassay. (1969) (80)
- Imparied calcitonin secretion in patients with Williams syndrome. (1985) (79)
- A radioimmunoassay for thyrocalcitonin. (1968) (79)
- Parathyroid hormone-related protein is expressed by prostatic neuroendocrine cells. (1994) (77)
- 1,25-Dihydroxyvitamin D3 increases bone alkaline phosphatase isoenzyme levels in human osteogenic sarcoma cells. (1983) (77)
- All major lung cancer cell types produce parathyroid hormone-like protein: heterogeneity assessed by high performance liquid chromatography. (1991) (74)
- Parathyroid hormone-related protein in the cardiovascular system. (1994) (74)
- Multiple hamartoma syndrome (Cowden's disease) associated with renal cell carcinoma and primary neuroendocrine carcinoma of the skin (Merkel cell carcinoma). (1992) (72)
- Immunoassay for human calcitonin. II. Clinical studies. (1971) (71)
- Lithium delays biochemical circadian rhythms in rats. (1982) (71)
- Prostate cancer progression, metastasis, and gene expression in transgenic mice. (1997) (70)
- Changes in plasma calcitonin and calcium during the migration of salmon. (1975) (70)
- Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate. (1998) (70)
- Smoltification and seawater adaptation in coho salmon (Oncorhynchus kisutch): plasma calcium regulation, osmoregulation, and calcitonin. (1989) (67)
- Hypercalcemia in disseminated coccidioidomycosis. (1977) (66)
- Demineralization in tetraplegic and paraplegic man over time (1997) (65)
- Mithramycin treatment of intractable hypercalcemia due to parathyroid carcinoma. (1970) (65)
- Direct evidence that PTHrP expression promotes prostate cancer progression in bone. (2005) (65)
- Evidence for a 1,25-dihydroxyvitamin D3 receptor-like macromolecule in rat pituitary. (1980) (65)
- Plasma chromogranin A as a marker of sympathochromaffin activity in humans. (1991) (64)
- Multiple markers for lung cancer diagnosis: validation of models for localized lung cancer. (1988) (63)
- 1,25-Dihydroxyvitamin D3 promotes in vitro morphologic and enzymatic changes in normal human monocytes consistent with their differentiation into macrophages. (1986) (62)
- Potential role of parathyroid hormone as an inhibitor of erythropoiesis in the anemia of renal failure. (1984) (62)
- Acute and chronic fluctuations of immunoreactive and biologically active plasma calcitonin in the rat. (1978) (62)
- The involvement of calcitonin in the reproductive physiology of the rainbow trout. (1986) (62)
- Effects of dietary calcium and age on parathyroid hormone, calcitonin and serum and milk minerals in the periparturient dairy cow. (1987) (61)
- Densitometric patterns of spinal cord injury associated bone loss (1997) (61)
- A short calcium infusion in the diagnosis of medullary thyroid carcinoma. (1974) (60)
- Effects of the intravenous administration of calcium on nephrogenous cyclic AMP: use as a parathyroid suppression test. (1978) (60)
- Plasma parathyroid hormone and calcium are related to sleep stage cycles. (1978) (60)
- Determinants of serum 1,25(OH)2D levels in renal disease. (1983) (60)
- Bone protein and peptide assays in the diagnosis and management of skeletal disease. (1991) (60)
- Immunohistological studies of medullary thyroid carcinoma and C cell hyperplasia. (1980) (59)
- Transdermal iontophoretic delivery of salmon calcitonin. (2000) (58)
- High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects. (2001) (58)
- Calcium and Phosphate Homeostasis (2014) (58)
- Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence. (2001) (57)
- Neuroendocrine modulation of calcitonin and parathyroid hormone in man. (1978) (57)
- Glucocorticoid regulation of parathyroid hormone-related peptide gene transcription in a human neuroendocrine cell line. (1989) (56)
- Secondary hyperparathyroidism in chronic renal disease. (1969) (55)
- Age-related changes of calcitonin secretion in females. (1980) (54)
- Drugs Five Years Later: Calcitonin as a Drug (1981) (54)
- PTH/PTHrP and Vitamin D Control Antimicrobial Peptide Expression and Susceptibility to Bacterial Skin Infection (2012) (53)
- Studies of the internalization of vitamin D3 metabolites by cultured osteogenic sarcoma cells and their application to a non-chromatographic cytoreceptor assay for 1,25-dihydroxyvitamin D3. (1980) (53)
- Calcium-regulating hormones across the menstrual cycle. (1986) (52)
- Prostate carcinoma (2000) (52)
- Clinical significance of elevation in neuroendocrine factors and interleukin-6 in metastatic prostate cancer. (1995) (52)
- Tumor-induced osteomalacia and rickets: a surgically curable syndrome. Report of two cases. (1976) (51)
- The humoral hypercalcemia of benignancy. A newly appreciated syndrome. (1996) (51)
- A radioimmunoassay for salmon calcitonin. (1974) (51)
- Calcitonin secretion in primary hyperparathyroidism. (1979) (51)
- Immunoreactive calcitonin in human cerebrospinal fluid. (1980) (51)
- Radioimmunoassay for calcitonin in medullary thyroid carcinoma. (1974) (50)
- Immunohistochemical localization of parathyroid hormone-related protein in prostatic intraepithelial neoplasia. (1995) (50)
- The gene for human chromogranin A (CgA) is located on chromosome 14. (1987) (49)
- Granin‐A, parathyroid hormone‐related protein, and calcitonin gene products in neuroendocrine prostate cancer (1998) (49)
- Evaluation of urinary cyclic 3'5'-adenosine monophosphate excretion in the differential diagnosis of hypercalcemia. (1972) (48)
- Evidence for a pro-calcitonin. (1974) (48)
- Effect of the menstrual cycle on calcium-regulating hormones in the normal young woman. (1980) (47)
- Osteoclasts can be induced in fish having an acellular bony skeleton. (1986) (47)
- Bone alkaline phosphatase in Paget's disease. (1991) (47)
- Plasma calcitonin as a marker of disease activity in patients with small cell carcinoma of the lung. (1981) (46)
- PTHrP secretion is stimulated by CT and inhibited by CgA peptides. (1989) (46)
- Radioiodine as an adjunct to the surgical treatment of medullary thyroid carcinoma. (1980) (46)
- Human pituitary tumors secrete chromogranin-A. (1989) (46)
- Exercise-induced hypercalcemia and the calciotropic hormones. (1985) (45)
- Synthesis and release of calcitonin-like immunoreactivity by anterior pituitary cells: evidence for a role in paracrine regulation of prolactin secretion. (1993) (43)
- Demonstration of chromogranin a in human neuroendocrine cell lines by immunohistology and immunoassay (1988) (43)
- The vitamin D endocrine system and the hematolymphopoietic tissue. (1984) (42)
- 17β-Estradiol Increases Plasma Calcitonin Levels in Salmonid Fish (1989) (42)
- Radioimmunoassay of calcitonin in plasma, normal thyroid, and medullary thyroid carcinoma of the rat. (1976) (40)
- Characterization of the cell-specific expression of parathyroid hormone-related protein in normal and neoplastic prostate tissue. (1998) (40)
- Measures of bone loss in rheumatoid arthritis. (1986) (40)
- Calcitonin receptor mRNA expression in the human prostate. (1996) (40)
- Secretion of calcitonin in hypocalcemic states in man. (1973) (39)
- Alveolar epithelial cells express and secrete parathyroid hormone-related protein. (1994) (39)
- Expression of the nucleoside triphosphate pyrophosphohydrolase PC‐1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast‐like osteosarcoma cells (1996) (38)
- Primary hyperparathyroidism, pregnancy, and neonatal hypocalcemia. (1984) (38)
- Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression. (2005) (38)
- Liposome-entrapped calcitonin and parathyroid hormone are orally effective in rats. (1991) (38)
- Control of secretion of thyrocalcitonin in the rabbit as evaluated by radioimmunoassay. (1969) (38)
- Changes in plasma bone GLA protein during treatment of bone disease (1982) (37)
- Simultaneous ectopic production of parathyroid hormone and calcitonin. (1976) (37)
- The role of calcitonin and parathyroid hormone in the pathogenesis of post-thyroidectomy hypocalcemia. (1981) (37)
- Intraperitoneal free fatty acids induce severe hypocalcemia in rats: A model for the hypocalcemia of pancreatitis (1990) (37)
- The regulation of calcitonin in normal human plasma as assessed by immunoprecipitation and immunoextraction. (1975) (36)
- Growth in vitro and ultrastructure of cells from a medullary carcinoma of the human thyroid gland: transformation by simian virus 40 and evidenc of thyrocalcitonin and prostaglandins. (1969) (36)
- The Bisphosphonate Olpadronate Inhibits Skeletal Prostate Cancer Progression in a Green Fluorescent Protein Nude Mouse Model (2006) (35)
- Calcitonin secretion by monolayer cultures of human C-cells derived from medullary thyroid carcinoma. (1975) (35)
- Parathyroid Hormone Related-Protein Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer (2014) (35)
- ACTH-secreting medullary carcinoma of the thyroid presenting a severe idiopathic osteoporosis and senile purpura: report of a case and review of the literature. (1978) (35)
- Explanation for unusual potency of salmon calcitonin. (1971) (35)
- Glucocorticoid receptor in clonal osteosarcoma cell lines: a novel system for investigating bone active hormones. (1980) (35)
- Immunochemical heterogeneity of calcitonin in renal failure. (1977) (34)
- Secretion of parathyroid hormone in patients with medullary thyroid carcinoma. (1974) (34)
- Parathyroid hormone-like protein: alternative messenger RNA splicing pathways in human cancer cell lines. (1994) (34)
- The evolving duty to disclose the presence of genetic disease to relatives (1998) (34)
- PTHrP stimulates prostate cancer cell growth and upregulates aldo-keto reductase 1C3. (2011) (34)
- Assessment of acute and chronic changes in parathyroid hormone secretion by a radioimmunoassay with predominant specificity for the carboxy-terminal region of the molecule. (1978) (34)
- Granins and prostate cancer. (1998) (33)
- Two-site assays of bone gla protein (osteocalcin) demonstrate immunochemical heterogeneity of the intact molecule. (1992) (33)
- Expression of peptide and other markers in lung cancer cell lines. (1985) (33)
- Multiple markers for lung cancer diagnosis: validation of models for advanced lung cancer. (1986) (33)
- Medullary carcinoma of the thyroid before age 2 years. (1980) (32)
- Elimination of the carboxy-terminal sequences of parathyroid hormone-related protein 1-173 increases production and secretion of the truncated forms. (1996) (32)
- Direct measurement of in vivo secretion of pig thyrocalcitonin by radioimmunoassay. (1971) (32)
- Mechanism of action of 1,25-dihydroxyvitamin D3-induced stimulation of alkaline phosphatase in cultured osteoblast-like cells (1983) (32)
- Hypercalcemia and systemic lupus erythematosus. (1996) (32)
- Calcitonin secretion in congenital nongoitrous cretinism. (1980) (32)
- Effects of sandostatin on plasma chromogranin-A levels in neuroendocrine tumors. (1989) (31)
- Chromogranin A is present in and released by fish endocrine tissue. (1987) (31)
- Magnesium in affective disorders. (1979) (31)
- Parathyroid hormone-related protein in patients with primary breast cancer and eucalcemia. (1998) (31)
- Influence of cadmium exposure on plasma calcium, vitellogenin and calcitonin in vitellogenic rainbow trout (1988) (31)
- Parathyroid hormone-related protein expression in human gastric adenocarcinomas not associated with hypercalcemia. (1995) (31)
- Calcitonin produces hypercalcemia in leopard sharks. (1985) (30)
- Calcitonin and calcitonin gene‐related peptide in the human prostate gland (2000) (30)
- 1,25-Dihydroxyvitamin D3 receptors in a subset of mitotically active lymphocytes from rat thymus. (1984) (30)
- Suppression and stimulation of calcitonin secretion in medullary thyroid carcinoma. (1971) (29)
- Parathyroid hormone-related protein, an autocrine growth inhibitor of alveolar type II cells. (1997) (29)
- Distribution of immunoreactive calcitonin in the rat pituitary gland. (1980) (28)
- Distinct patterns of chromogranin A-related species can be demonstrated in endocrine cells. (1990) (28)
- Production of parathyroid hormone by metastatic parathyroid carcinoma. (1968) (28)
- Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells. (2007) (28)
- The parathyroid hormone-related protein (PTHrP) gene preferentially utilizes a GC-rich promoter and the PTHrP 1-139 coding pathway in normal human amnion. (1992) (27)
- GSK3 and PKB/Akt are associated with integrin‐mediated regulation of PTHrP, IL‐6 and IL‐8 expression in FG pancreatic cancer cells (2005) (27)
- Immunological stability of calcitonin in plasma. (1972) (27)
- Immunohistological studies of nonthyroidal calcitonin-producing tumors. (1980) (27)
- Receptor for 1,25-dihydroxyvitamin D3 in GH3 pituitary cells. (1982) (27)
- Calcitonin secretion in vitro. I. Preparation of monolayer C-cell cultures. (1974) (26)
- Influence of Spondylopathy on Bone Densitometry Using Dual Energy X-Ray Absorptiometry (1997) (26)
- Calcium-stimulated parathyroid hormone-like protein secretion: potentiation through a protein kinase-C pathway. (1991) (26)
- Medical management of the hypercalcemia of malignancy. (1974) (26)
- Importance of liposome complexing volume in transfection optimization. (1996) (26)
- 41Ca and accelerator mass spectrometry to monitor calcium metabolism in end stage renal disease patients. (2005) (26)
- Human pancreatic adenocarcinomas express parathyroid hormone-related protein. (2001) (26)
- Hypercalcemia in malignant and inflammatory diseases. (2002) (26)
- Expression of parathyroid hormone-related peptide and its receptor messenger ribonucleic acid in human amnion and chorion-decidua: implications for secretion and function. (1995) (26)
- Intrapulmonary Drug Delivery of Salmon Calcitonin (1997) (25)
- Parathyroid Hormone-related Protein as a Novel Tumor Marker in Pancreatic Adenocarcinoma (2002) (25)
- Hypercalcemia due to Parathyroid Hormone-Related Protein Secretion by Melanoma (1998) (25)
- Proteolysis of ProPTHrP(1-141) by "prohormone thiol protease" at multibasic residues generates PTHrP-related peptides: implications for PTHrP peptide production in lung cancer cells. (2001) (25)
- Parathyroid Hormone Production in vitro by Human Parathyroid Cells Transformed by Simian Virus 40 (1968) (25)
- Parathyroid hormone-related protein, an autocrine regulatory factor in alveolar epithelial cells. (1996) (24)
- Treatment of Paget's disease--taming the wild osteoclast. (2005) (24)
- Immunoreactive calcitonin in catecholamine storage vesicles of human pheochromocytoma. (1983) (24)
- Renal osteodystrophy: magnification radiography of target sites of absorption. (1981) (24)
- Parathyroid hormone-related protein ameliorates death receptor-mediated apoptosis in lung cancer cells. (2003) (24)
- The Extracellular Matrix Differentially Regulates the Expression of PTHrP and the PTH/PTHrP Receptor in FG Pancreatic Cancer Cells (2004) (24)
- Somatostatin does not suppress plasma parathyroid hormone. (1976) (24)
- Immunoreactive parathyroid hormone-related protein is present in human seminal plasma and is of prostate origin. (1994) (24)
- The coregulation of secretion and cytoplasmic ribonucleic acid of chromogranin-A and calcitonin by phorbol ester in cells that produce both substances. (1988) (24)
- Hypercalcemia in disseminated coccidioidomycosis: expression of parathyroid hormone-related peptide is characteristic of granulomatous inflammation. (2012) (23)
- Calcitonin secretion in vitro. II. Regulatory effects of enteric mammalian polypeptide hormones on trout C-cell cultures. (1976) (23)
- MOLECULAR ACTION OF 1,25‐DIHYDROXYVITAMIN D3: NEW CULTURED CELL MODELS * (1981) (23)
- Bone turnover in male puberty: A longitudinal study (1985) (23)
- Should serum calcitonin be routinely measured in patients with thyroid nodules--will the law answer before endocrinologists do? (2004) (22)
- Plasma calcium and calcitonin in the marine teleost, Gadus morhua. (1985) (22)
- The interaction of lithium and time-of-day on calcium, magnesium, parathyroid hormone, and calcitonin in rats (1982) (22)
- Calcium and cholecalciferol: effects of small supplements in normal men. (1988) (22)
- Presence by radioimmunoassay of a calcitonin-like substance in porcine pituitary glands. (1980) (21)
- Calcitonin as a drug. (1981) (21)
- Renal metabolism of calcitonin. (1988) (21)
- Evaluation of provocative tests in suspected medullary carcinoma of the thyroid:heterogeneity of calcitonin responses to calcium and pentagastrin. (1984) (21)
- A cloned chromogranin A (CgA) cDNA detects a 2.3Kb mRNA in diverse neuroendocrine tissues. (1986) (21)
- Salmon calcitonin-like immunoactivity in extracts of Tetrahymena pyriformis. (1985) (21)
- A carboxyl leucine-rich region of parathyroid hormone-related protein is critical for nuclear export. (2006) (20)
- Mass spectrometric immunoassay for parathyroid hormone-related protein. (2000) (20)
- Immunoreactive-β-endorphin, -adrenocorticotropin and -calcitonin in extracts of anaplastic or differentiated (rat) medullary thyroid carcinoma (1979) (20)
- Coexpression of parathyroid hormone-related protein and its receptor in breast carcinoma: a potential autocrine effector system. (1998) (20)
- Immunohistological studies of artiodactyl and teleost pituitaries with antisera to calcitonin. (1980) (20)
- Diminished prepartal plasma calcitonin concentration on cows developing parturient hypocalcemia. (1975) (20)
- Hypercalcemia in association with a Leydig cell tumor in the rat: a model for tumor-induced hypercalcemia in man. (1982) (19)
- Influence of heterotopic ossification of the hip on bone densitometry: a study in spinal cord injured patients (1998) (19)
- Chromogranin A: studies in the endocrine system. (1984) (19)
- Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells (2005) (19)
- Adenohypophyseal hormones in the CSF. (1982) (19)
- Prolactin and calcitonin responses to parathyroid hormone infusion in hypoparathyroid, pseudohypoparathyroid, and normal subjects. (1981) (18)
- Sex-Specific Survival Advantage with Parathyroid Hormone–Related Protein in Non–Small Cell Lung Carcinoma Patients (2006) (18)
- CYTORECEPTOR ASSAY FOR 1,25-DIHYDROXYVITAMIN D3: A NOVEL RADIOMETRIC METHOD BASED ON BINDING OF THE HORMONE TO INTRACELLULAR RECEPTORS IN VITRO (1980) (18)
- Parathyroid Hormone-Related Protein in Tracheal Aspirates of Newborn Infants (1998) (18)
- Liposome entrapment enhances the hypocalcemic action of parenterally administered calcitonin. (1984) (18)
- Serum bone Gla protein and other biochemical estimates of bone turnover in early postmenopausal women during prophylactic treatment for osteoporosis. (2009) (17)
- Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A. (2004) (16)
- Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro. (2005) (16)
- Proapoptotic effects of parathyroid hormone-related protein in type II pneumocytes. (2003) (16)
- Medullary thyroid carcinomas express chromogranin A and a novel neuroendocrine protein recognized by monoclonal antibody HISL-19. (1988) (16)
- Radioimmunoassay for bovine calcitonin. (1972) (16)
- Iodine deficiency produces hypercalcemia and hypercalcitonemia in rats. (1978) (15)
- Parathyroid hormone-related protein reduces alveolar epithelial cell proliferation during lung injury in rats. (2000) (15)
- Dissociation between ACTH and beta endorphin immunoreactivity in cells of the rat pituitary gland. (1980) (15)
- Ultimobranchial gland of the trout (Salmo gairdneri). I. Immunohistology and radioimmunoassay of calcitonin. (1976) (15)
- REGULATION OF CALCITONIN SECRETION IN VITRO (1976) (15)
- Calcium and skeletal metabolism. (1975) (14)
- Heat shock proteins bind calcitonin. (1990) (14)
- Impaired calcitonin secretion Williams syndrome in patients with (1985) (14)
- Stability of a Transdermal Salmon Calcitonin Formulation (2003) (14)
- Parathyroid hormone-related protein-(38-64) regulates lung cell proliferation after silica injury. (2002) (14)
- Humoral hypercalcemia caused by a rat Leydig-cell tumor is associated with suppressed parathyroid hormone secretion and increased urinary cAMP excretion. (1983) (13)
- Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression (2010) (13)
- Seasonal levels of serum parathyroid hormone, calcitonin and alkaline phosphatase in relation to antler cycles in white-tailed deer. (1984) (13)
- Parathyroid hormone-related protein, chromogranin A, and calcitonin gene products in the neuroendocrine skin carcinoma cell lines MKL1 and MKL2. (1991) (13)
- Calcitonin levels in sera of infants and children: Relations to age and periods of bone growth (1984) (13)
- Chromogranin A Peptide-Specific Antisera and High-Performance Size Exclusion Chromatography Demonstrate Amino-Terminal and Carboxy-Terminal Fragments of the Native Molecule in Human Cell Lines (1994) (13)
- Neoplastic hormone-producing cells of the placenta produce and secrete parathyroid hormone-related protein. Studies by immunohistology, immunoassay, and polymerase chain reaction. (1994) (13)
- Improved radioimmunoassay for calcitonin using 125 I-labelled calcitonin purified by gel filtration. (1972) (13)
- Identification and characterization of a neuroendocrine-specific 5'-regulatory region of the human chromogranin A gene. (1995) (13)
- Transcriptional regulation of the human chromogranin A gene by its 5′ distal regulatory element: novel effects of orientation, structure, flanking sequences, and position on expression (1996) (12)
- Causes of hypercalcemia in a population of military veterans in the United States. (2006) (12)
- Pathogenesis of osteomalacia in secondary hyperparathyroidism after gastrectomy. (1972) (12)
- Pituitary cells secrete calcitonin in the reverse hemolytic plaque assay. (1987) (11)
- Incidental finding of metastatic papillary thyroid carcinoma in a patient with primary hyperparathyroidism. (2007) (11)
- Cell cycle actions of parathyroid hormone-related protein in non-small cell lung carcinoma. (2009) (11)
- EFFECTS OF XYLAZINE IMMOBILIZATION ON BIOCHEMICAL AND ENDOCRINE VALUES IN WHITE-TAILED DEER (1984) (11)
- The calcium endocrine system of adolescent rhesus monkeys and controls before and after spaceflight. (2002) (11)
- Two-site immunoradiometric assay of intact salmon calcitonin. (1992) (11)
- Comparative tissue distribution of the processing enzymes “prohormone thiol protease”, and prohormone convertases 1 and 2, in human PTHrP-producing cell lines and mammalian neuroendocine tissues (2001) (11)
- Metachronous double parathyroid adenomas involving two different cell types: chief cell and oxyphil cell. (2003) (11)
- Prognostic implications of parathyroid hormone-related protein in males and females with non--small-cell lung cancer. (2011) (11)
- Management of primary hyperparathyroidism. (1993) (11)
- Parathyroid hormone-related protein response to hyperoxic lung injury. (2002) (11)
- Immunoassay of calcitonin in rat medullary thyroid carcinoma. (1976) (11)
- Thymic parathyroid carcinoma and postoperative hungry bone syndrome. (2003) (10)
- Hypercalcemia in rats bearing growth hormone- and prolactin-secreting transplantable pituitary tumors. (1985) (10)
- Comparison of 1,25-, 25-, and 24,25-hydroxylated vitamin D3 binding in fetal rat calvariae and osteogenic sarcoma cells (2006) (10)
- Thyroglobulin and calcitonin in patients with nontoxic goiter. (1978) (10)
- General principles, problems and interpretation in the radioimmunoassay of calcitonin. (1984) (10)
- Congenital craniopharyngioma and hypercalcemia induced by parathyroid hormone-related protein. (2007) (9)
- Preparation and immunological characteristics of biologically active radioiodinated human calcitonin. (1977) (9)
- Humoral hypercalcaemia of "benignancy" (1995) (9)
- Islet amyloid polypeptide (amylin) increases the renal excretion of calcium in the conscious dog (1994) (9)
- Hypercalcemia: mechanisms, differential diagnosis, and remedies. (1996) (9)
- Parathyroid hormone-related protein and lung injury after pulmonary thromboendarterectomy (2001) (9)
- Two-site immunofluorometric assay of intact salmon calcitonin with improved sensitivity. (1997) (9)
- Concurrent primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with multiple endocrine neoplasia type 1. (2011) (9)
- Contamination of DFP-treated leucine aminopeptidase with multiple endopeptidases. (1969) (8)
- Serum bone Gla protein variations during estrogen and calcium prophylaxis of postmenopausal women (1984) (8)
- Localization of hyperfunctioning parathyroids. The surgeons' riddle. (1970) (8)
- MULTICENTRE COMPARISON OF 1,25-DIHYDROXYCHOLECALCIFEROL MEASUREMENTS IN HUMAN SERUM (1983) (8)
- Splenic, thymic, bony and lymph node metastases from orthotopic human lung carcinomas in immunocompromised mice. (2000) (8)
- RADIOIMMUNOASSAY OF PARATHYROID HORMONE: STUDIES OF THE CONTROL OF SECRETION OF THE HORMONE AND PARATHYROID FUNCTION IN CLINICAL DISORDERS. (1969) (8)
- There's something fishy and perhaps even fowl about the mammalian calcitonin receptor and its ligand. (1997) (7)
- Unique subset of thymic epithelial cells defined by the expression of a novel neuroendocrine antigen. (1988) (7)
- Medullary Thyroid Carcinoma (1983) (7)
- Effect of different modes of dialysis on serum erythropoietin levels in pediatric patients (1988) (7)
- 1,25-DIHYDROXYVITAMIN D3 RECEPTORS IN CANCER (1980) (7)
- Metabolism of calcium and phosphorus during pregnancy and lactation in white-tailed deer. (1985) (7)
- Predicting PTH pulses and patterns in osteoporosis. (1995) (7)
- Reactivity of ACTH and synthetic ACTH peptides with antisera to human calcitonin. (1979) (7)
- Role of parathyroid hormone-related protein in lung cancer cell survival. (2004) (7)
- Growth factor control of type II cell apoptosis. (1999) (7)
- Effect of estrogens and phosphorus depletion on plasma calcitonin in the rat (1983) (6)
- [Localization of the parathyroid adenoma]. (1969) (6)
- Calcitonin in clinical medicine. (1978) (6)
- Absence of hyperparathyroidism in severe liver disease (1989) (6)
- CHAPTER 9 – Immunoassays for PTH and PTHrP: Clinical Applications (2001) (6)
- Many Courts Still Frye Scientific Evidence (2002) (6)
- Clinical Essentials of Calcium and Skeletal Disorders (1998) (5)
- Genomic torts: the law of the future -- the duty of physicians to disclose the presence of a genetic disease to the relatives of their patients with the disease. (1997) (5)
- The distribution of biologically active and inactive radioiodinated human calcitonin in the rat. (1978) (5)
- Cloning of the human chromogranin-A promoter and identification of a sequence that possesses enhancer-like activity (1994) (5)
- Immunoassays for PTH and PTHrP (2001) (5)
- Rapid, simple identification of individual osteoblastic cells and their specific products by cell blotting assay (1989) (5)
- Amino-terminal and midmolecule parathyroid hormone-related protein, phosphatidylcholine, and type II cell proliferation in silica-injured lung. (2003) (5)
- 17 beta-estradiol increases plasma calcitonin levels in salmonid fish. (1989) (5)
- Coherent Expression Chromosome Cluster Analysis Reveals Differential Regulatory Functions of Amino-Terminal and Distal Parathyroid Hormone-Related Protein Domains in Prostate Carcinoma (2005) (5)
- A high-fat diet increases calcitonin secretion in the rat. (1989) (5)
- Sensitivity of the thyroid and parathyroid glands to radiation. (1978) (5)
- Deletion of the gene encoding calcitonin and calcitonin gene-related peptide α does not affect the outcome of severe infection in mice. (2013) (5)
- Mineral metabolic effects of thyroidectomy and long-term outcomes in a family with MEN 2A. (1992) (5)
- CALBINDIN-D28K DISTRIBUTION IN CHICK ULTIMOBRANCHIAL AND RAT THYROID GLANDS (1987) (5)
- Hypercalcitoninism without hypercalcitoninemia. (1981) (4)
- Plasma Calcitonin in the Bovine Species 1 (1979) (4)
- The Short-Term Effects of Conjugated Estrogen on Bone Turnover in Older Women (1995) (4)
- Biochemical markers of bone turnover in rheumatoid arthritis. Relation to anti-inflammatory treatment, sex, and menopause. (1986) (4)
- Localization of parathyroid adenoma. (1969) (3)
- 41 Ca and Accelerator Mass Spectrometry to Monitor Calcium Metabolism in End Stage Renal Disease Patients (2005) (3)
- 4 – The Thyroid Gland in Skeletal and Calcium Metabolism (1978) (3)
- Hypercalcemia and local production of parathyroid hormone-related protein by a perisellar rhabdomyosarcoma after remote pituitary irradiation. (2005) (3)
- Calcium metabolism in Bion 11 monkeys. (2000) (3)
- Osteology: Further Debate (1999) (2)
- Endogenous parathyroid hormone response to thyrocalcitonin-induced hypocalcemia in the cow. (1971) (2)
- Games of hormones: the para-endocrinology of sport. (2006) (2)
- Medical and scientific organizations and scientific evidence in U.S. trials: lessons from European legal theory. (1999) (2)
- Genomic torts: the law of the future--the duty of physicians to disclose the presence of a genetic disease to the relatives of their patients with the disease. (1998) (2)
- Parathyroid hormone-related protein and lung injury. (2002) (2)
- Synthesis ofaBiologically Active N-Terminal Tetratriacontapeptide ofParathyroid Hormone (1971) (2)
- 891 ETIOLOGY OF FIRST DAY HYPOCALCEMIA (FDH): ROLE OF PTH AND CALCITONIN? (1978) (2)
- 8 – Calcitonin Secretion (1982) (2)
- Biochemical markers of bone turnover in rheumatoid arthritis (2009) (2)
- Glucocorticoids increase the 1,25(OH)2D3 receptor concentration in rat osteogenic sarcoma cells (1984) (2)
- The α2β1 integrin regulates the malignant phenotype on type I collagen in pancreatic cancer cell lines (2006) (1)
- Plasma calcitonin in rats with renal failure (1988) (1)
- Regulation of the expression of the gene for the parathyroid hormone-like protein (1992) (1)
- Courts complicate industry-academia ties. (2011) (1)
- NUDE MOUSE MODEL (CAC-8) OF HUMORAL HYPERCALCEMIA OF MALIGNANCY (HHM) WITH INCREASED SERUM LEVELS OF 1,25-DIHYDROXYCHOLECALCIFEROL (1,25(OH)2D): IN VIVO AND IN VITRO STUDIES (1988) (1)
- Parathyroid hormone-related protein expression in human pancreatic adenocarcinoma (2000) (1)
- Production of Other Bioactive Substances by MTC (1983) (1)
- Hormonal regulation of cyclic 3',5'-AMP in specific recetor tissues. Biological effects of a synthetic N-terminal tetratriacontapeptide of parathyroid hormone. (1971) (1)
- Calcitonin heterogeneity:in vivo andin vitro studies (1976) (1)
- Identification of DU 145 prostate cancer cell proteins that bind to the carboxy-terminal peptide of human PTHrP in vitro (2006) (1)
- Activation of the 1,25-dihydroxyvitamin D3 receptor in cultured rat osteogenic sarcoma cells. (1985) (1)
- Diagnostic applications of calcitonin immunoassay. (1974) (1)
- Harvard v. Canada: The myc Mouse That Still Squeaks in the Maze of Biopatent Law (2001) (1)
- Effect of bromocriptine on serum PTH, calcium and phosphate levels in azotemic rats. (1985) (1)
- Parathyroid Hormone-related Protein Induces Interleukin 8 Production by Prostate Cancer Cells via a Novel Intracrine Mechanism Not Mediated by its Classical Nuclear Localization Sequence 1 (2001) (1)
- Ca and Accelerator Mass Spectrometry to Monitor Calcium Metabolism in End Stage Renal Disease Patients (2005) (1)
- R 1 1 PARATHYROID HORMONE-RELATED PROTEIN AMELIORATES DEATH RECEPTOR-MEDIATED APOPTOSIS IN LUNG CANCER CELLS (2003) (0)
- Treatment of Multiple Endocrine Neoplasia (1983) (0)
- Patterns of osteoporosis in spinal cord injury (2006) (0)
- Sequence Mechanism Not Mediated by its Classical Nuclear Localization Production by Prostate Cancer Cells via a Novel Intracrine Parathyroid Hormone-related Protein Induces Interleukin 8 Updated (2001) (0)
- and Characterization of a Neuroendocrine-Specific E-Regulatory Region of the Human Chromogranin A Gene* (1995) (0)
- Calcitonin Secretion in Normal and Growth Hormone Deficient Children (1988) (0)
- Differential Diagnosis of Hypercalcitoninemia (1983) (0)
- 19 – Parathyroid Hormone (1978) (0)
- Abstract 2322: Knockdown of the beta 1 integrin subunit inhibits tumor growth and metastasis in an orthotopic mouse model of pancreatic cancer (2010) (0)
- Combination therapy for osteoporosis: a counter-regulatory conundrum (2006) (0)
- A RADIOIMMUNOASSA Y FOR THYROCALCITONIN BY L. J. DEFTOS, (0)
- Akt Regulates Parathyroid Hormone-Related Protein Expression In Lung Cancer (2010) (0)
- Parathormone and calcitonin in the pathogenesis of neonatal hypocalcemia (1979) (0)
- Parathyroid hormone-related protein, and autocrine regulatory factor in aveolar epithelial cells (1996) (0)
- OSTEOLOGY: FURTHER DEBATE. AUTHORS' REPLY (1999) (0)
- Decreased Integrin Expression And Matrix Adhesion In PTHrP-Producing Lung Cancer Cells (2010) (0)
- Immunoreactive-beta-endorphin, -adrenocorticotropin and -calcitonin in extracts of anaplastic or differentiated (rat) medullary thyroid carcinoma. (1979) (0)
- Opposing Survival Effects Of Amino And Carboxyl-Terminal Parathyroid Hormone-Related Protein In Non-Small Cell Lung Cancer (2012) (0)
- Androgen Suppression Increases PTH1R Levels and Reduces Lung Cancer Growth. (2009) (0)
- A RADIOIMMUNOASSA Y FOR THYROCALCITONIN (0)
- Parathyroid Hormone-related Protein in Patients with Primary Breast Cancer and Eucalcemia1 (2006) (0)
- 41 Ca: A New Tool for Bone Health Assessment (2008) (0)
- Plasma calcitonin measurement as a marker for cancer. (1976) (0)
- Parathyroid Hormone-Related Protein Expression in NSCLC Predicts Improved Survival. (2009) (0)
- Immunochemical analysis of human calcitonin (HCT) (1976) (0)
- Postdoc Servitude in the Academic-Industrial Alliance (1999) (0)
- No diurnal variations in calcitonin and vitamin D2. (1985) (0)
- Physician assistance in dying. (1997) (0)
- Hyperparathyroidism and hypoparathyroidism (1988) (0)
- Calcitonin secretion in renal disease (1976) (0)
- Clinical Consequences of Hypercalcitoninemia (1983) (0)
- PTHrP and Cancer (2005) (0)
- Serum 1,25-Dihydroxycholecalciferol and 25-Hydroxycholecalciferol in Epileptic Patients Taking Anticonvulsants* (1985) (0)
- PTHRP REGULATES ALDO-KETO REDUCTASE (AKR)1C3 AND GROWTH IN PROSTATE CANCER CELLS (2008) (0)
- 286 STUDIES OF PLASMA CALCITONIN IN HYPOITUITARISM AND HYPOTHYROIDISM (1978) (0)
- Parathyroid Hormone-related Protein in Patients with Primary Breast Cancer and Eucalcemia 1 (2006) (0)
- Multiple Endocrine Neoplasia (MEN) (1983) (0)
- Table 2, Distribution of Calcium, Phosphorus, and Magnesium (2014) (0)
- Secretin's effect on calcitonin (CT) secretion: evidence for multifactorial regulation of C cell function in vitro (1975) (0)
- The calcemic hormones and chromogranin a (CGA) peptides regulate each other's production (1992) (0)
- Title Page / Contents / Acknowledgements / Dedication (1983) (0)
- References / Subject Index (1983) (0)
- Extraction of a substance with calcitonin-like immunoreactivity from pituitary glands of intact and thyroidectomized rats (1983) (0)
- Ethics and genetics. (2003) (0)
- Author's response (1988) (0)
- OC1. Translating a novel urine test for early detection and accurate assessment of bone abnormalities (2008) (0)
- Abstracts of the second annual scientific meeting of the american society for bone and mineral research (2006) (0)
- Differential release of calcitonin in sheep to calcium and pentagastrin stimulation. (1978) (0)
- Multifactorial regulation of c cell function in vitro: GI hormones (1975) (0)
- Effect of gastrin on calcitonin (CT) secretion in man (1973) (0)
- PTHrP IS OVEREXPRESSED IN AIDS-RELATED LYMPHOMA.: 120 (1997) (0)
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