Laurence J. Marton
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(Suggest an Edit or Addition)Laurence J. Marton's Published Works
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Published Works
- Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases (2007) (667)
- Polyamines as targets for therapeutic intervention. (1995) (664)
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia (2012) (560)
- Subtype and pathway specific responses to anticancer compounds in breast cancer (2011) (439)
- Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats. (1980) (354)
- Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue. (1986) (236)
- Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes (2009) (196)
- Implications and concepts of polyamine‐nucleic acid interactions (1991) (162)
- Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones. (1997) (158)
- Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding. (1990) (151)
- Spermine-DNA interactions: a theoretical study. (1986) (137)
- Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography. (1980) (129)
- Polyamines are necessary for the survival of human small-cell lung carcinoma in culture. (1981) (129)
- 4 – Molecular and Cellular Functions of the Polyamines (1987) (125)
- Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. (1990) (122)
- More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde. (1975) (122)
- Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography. (1977) (117)
- Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer. (1973) (115)
- Polyamines in biology and medicine (1981) (104)
- Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition. (1981) (102)
- Stabilization of erythrocyte membranes by polyamines. (1983) (98)
- Changes in L-ornithine decarboxylase activity during the cell cycle. (1976) (93)
- Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells (2012) (88)
- The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors. (1976) (87)
- The Polyamine Binding Site in Inward Rectifier K+ Channels (2006) (85)
- Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor. (1981) (85)
- Conformationally restricted analogues of 1N,12N-bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines. (1998) (83)
- Polyamine metabolism in a rat brain tumor cell line: Its relationship to the growth rate (1975) (81)
- Polyamine content of AKR leukemic cells in relation to the cell cycle. (1973) (80)
- Predictive value of cerebrospinal fluid polyamines in medulloblastoma. (1979) (76)
- Somatic mutational mechanisms involved in intestinal tumor formation in Min mice. (1997) (72)
- A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells. (2003) (72)
- Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor. (1981) (71)
- The interaction of spermine and pentamines with DNA. (1987) (70)
- Self‐immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy (2017) (69)
- Polyamine depletion influences drug-induced chromosomal damage. (1982) (69)
- Inhibition of the LSD 1 ( KDM 1 A ) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia (2013) (68)
- Conformationally restricted analogues of 1N,14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells. (2001) (67)
- Correlation between the effects of polyamine analogues on DNA conformation and cell growth. (1989) (67)
- Csf polyamines: A new and important means of monitoring patients with medulloblastoma (1981) (64)
- Prediction of human tumor cell chemosensitivity using the sister chromatid exchange assay. (1986) (64)
- Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells. (1983) (64)
- Changes in polyamine metabolism in WI38 cells stimulated to proliferate. (1975) (62)
- Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro. (1982) (60)
- Antizyme induction by polyamine analogues as a factor of cell growth inhibition. (2002) (58)
- Determination of acetaminophen and phenacetin in plasma by high-pressure liquid chromatography. (1977) (58)
- Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells (2003) (58)
- Novel Synthetic Polyamines Are Effective in the Treatment of Experimental Microsporidiosis, an Opportunistic AIDS-Associated Infection (2002) (57)
- Polyamines: A high correlation with cell replication (1975) (57)
- alpha-Difluoromethylornithine-induced polyamine depletion of 9L tumor cells modifies drug-induced DNA cross-link formation. (1983) (56)
- Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. (1993) (54)
- High-pressure liquid chromatographic analysis of diazepam, oxazepam and N-desmethyldiazepam in human blood. (1978) (52)
- Polyamine analogues targeting epigenetic gene regulation. (2009) (52)
- Improved liquid-chromatographic method for determination of serum cortisol. (1979) (52)
- Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents. (1998) (49)
- Simultaneous liquid-chromatographic determination of 12 common sedatives and hypnotics in serum. (1978) (48)
- Biochemical markers of central nervous system tumors measured in cerebrospinal fluid and their potential use in diagnosis and patient management: a review. (1979) (48)
- Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum. (1983) (48)
- Further evidence for the use of polyamines as biochemical markers for malignant tumors. (1982) (48)
- Molecular dynamics of spermine-DNA interactions: sequence specificity and DNA bending for a simple ligand. (1989) (46)
- An automated micromethod for the quantitative analysis of di‐ and polyamines utilizing a sensitive high pressure liquid chromatographic procedure (1974) (46)
- Long-chain polyamines (oligoamines) exhibit strong cytotoxicities against human prostate cancer cells. (2003) (43)
- Polyamine depletion of the MTW9 mammary tumor and subsequent elevation of spermidine in the sera of tumor-bearing rats as a biochemical marker of tumor regression. (1974) (43)
- Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells. (1992) (41)
- Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse. (1977) (41)
- Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin. (1981) (41)
- Phase I-II clinical trial with alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis. (1987) (40)
- A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice (2003) (40)
- Polyamine depletion of tumor tissue and subsequent elevation of spermidine in the sera of rats with 3924A hepatomas after 5-fluorouracil administration. (1974) (39)
- Simultaneous measurement of phenobarbital, diphenylhydantoin, and primidone in blood by high-pressure liquid chromatography. (1976) (38)
- A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interactions. (1987) (38)
- Cerebrospinal fluid polyamines in patients with Glioblastoma multiforme and anaplastic astrocytoma. (1980) (37)
- Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors (1974) (37)
- Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells. (2004) (36)
- Polyamine Analogues Down-regulate Estrogen Receptor α Expression in Human Breast Cancer Cells* (2006) (36)
- Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro. (1983) (36)
- In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells (2008) (35)
- Biphasic stimulation of polyamine biosynthesis in primary mouse kidney cells by infection with polyoma virus:uncoupling from DNA and rRNA synthesis. (1976) (35)
- Decreased cytotoxicity of aziridinylbenzoquinone caused by polyamine depletion in 9L rat brain tumor cells in vitro. (1984) (35)
- Simultaneous determination of phosphatidylglycerol and the lecithin/sphingomyelin ratio in amniotic fluid. (1978) (35)
- Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells. (2004) (34)
- A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047 (2009) (34)
- Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs (2007) (34)
- Comparison and characterization of growth inhibition in L1210 cells by alpha-difluoromethylornithine, an inhibitor of ornithine decarboxylase, and N1,N8-bis(ethyl)spermidine, an apparent regulator of the enzyme. (1986) (33)
- A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus. (1995) (33)
- A Simultaneous High-Performance Liquid Chromatographic Analysis of the Most Common Anticonvulsants and Their Metabolites in the Serum (1978) (33)
- Calcium channels in PDGF-stimulated A172 cells open after intracellular calcium release and are not voltage-dependent. (1991) (32)
- cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines. (2001) (32)
- A method for the determination of polyamines in cerebrospinal fluid (1974) (32)
- Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy (1993) (32)
- Radiation brain injury is reduced by the polyamine inhibitor alpha-difluoromethylornithine. (1994) (31)
- Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes (2011) (31)
- Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo (1998) (31)
- Antizyme induction mediates feedback limitation of the incorporation of specific polyamine analogues in tissue culture. (2004) (31)
- Fluorometric liquid-chromatographic determination of serum cortisol. (1981) (31)
- Simultaneous liquid-chromatographic determination of zinc protoporphyrin IX, protoporphyrin IX, and coproporphyrin in whole blood. (1980) (31)
- The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib. (2008) (29)
- Reaction of beta-lapachone and related naphthoquinones with 2-mercaptoethanol: a biomimetic model of topoisomerase II poisoning by quinones. (1998) (28)
- [1N,12N]Bis(Ethyl)-cis-6,7-Dehydrospermine: a New Drug for Treatment and Prevention of Cryptosporidium parvum Infection of Mice Deficient in T-Cell Receptor Alpha (2000) (28)
- Determination of organic acids in biological fluids by ion chromatography: plasma lactate and pyruvate and urinary vanillylmandelic acid. (1980) (28)
- Effect of difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the topoisomerase II-mediated DNA scission produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide in L1210 murine leukemia cells. (1985) (28)
- Liquid-chromatographic analysis for serum theophylline in less than 70 seconds. (1982) (27)
- Rapid method for screening toxic drugs in serum with liquid chromatography. (1981) (27)
- Differential polyamine analogue effects in four human breast cancer cell lines. (2006) (26)
- Polyamines in malignant melanoma. Urinary excretion and disease progress (1976) (26)
- The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer (2009) (25)
- Treatment with a polyamine analog alters DNA-matrix association in HeLa cell nuclei: a nucleoid halo assay. (1993) (25)
- Suppression and regression of choroidal neovascularization by polyamine analogues. (2005) (25)
- Attachment of A172 human glioblastoma cells affects calcium signalling: a comparison of image cytometry, flow cytometry, and spectrofluorometry. (1991) (25)
- Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs. (1992) (25)
- Liquid-chromatographic determination of tobramycin in serum with spectrophotometric detection. (1983) (24)
- Liquid‐Chromatographic Determination of Antidysrhythmic Drugs: Procainamide, Lidocaine, Quinidine, Disopyramide, and Propranolol (1981) (24)
- Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice. (2003) (24)
- Reduction of the putative CD44+CD24− breast cancer stem cell population by targeting the polyamine metabolic pathway with PG11047 (2010) (24)
- Molecular Basis of Inward Rectification: Structural Features of the Blocker Defined by Extended Polyamine Analogs (2005) (24)
- Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells. (1979) (24)
- New DNA polymorphism: evidence for a low salt, left-handed form of poly(dG-m5dC). (1985) (24)
- Decreased Cytotoxicity of 1-β-d-Arabinofuranosylcytosine in 9L Rat Brain Tumor Cells Pretreated with α-Difluoromethylornithine in Vitro (1983) (24)
- Induction of cardiac L-ornithine decarboxylase by nicotinamide and its regulation by putrescine. (1978) (24)
- Cell cycle age response of 9L cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and modification by alpha-difluoromethylornithine. (1983) (23)
- Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts. (1994) (23)
- Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation. (1980) (23)
- Recognition of Z-RNA and Z-DNA determinants by polyamines in solution: experimental and theoretical studies. (1988) (22)
- Relationship of urinary polyamines to tumor activity and tumor volume in patients. (1984) (22)
- Effects of alpha-difluoromethylornithine on the growth of 9L rat brain tumor multicellular spheroids and their response to 1,3-bis(2-chloroethyl)-1-nitrosourea. (1984) (22)
- Scanning the Topography of Polyamine Blocker Binding in an Inwardly Rectifying Potassium Channel* (2013) (21)
- Possible factors in the potentiation of 1-(2-chloroethyl)-3-trans-4-methylcyclohexyl-1-nitrosourea cytotoxicity by alpha-difluoromethylornithine in 9L rat brain tumor cells. (1984) (21)
- Blocker protection by short spermine analogs: refined mapping of the spermine binding site in a Kir channel. (2008) (21)
- Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs (2007) (21)
- Polyamine metabolism in tumor, spleen and liver of tumor‐bearing rats (1974) (20)
- Differential potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine in chloroethylnitrosourea-sensitive and -resistant 9L rat brain tumor cells in vitro. (1983) (20)
- Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells. (1980) (20)
- Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide. (1993) (20)
- Histone Deacetylase Inhibition Overcomes Drug Resistance through a miRNA-Dependent Mechanism (2013) (19)
- Design and testing of novel cytotoxic polyamine analogues. (1994) (19)
- Effects of treatment with DNA-directed cancer chemotherapeutic agents after polyamine depletion. (1987) (19)
- Theoretical and experimental characterization of polyamine/DNA interactions. (1988) (19)
- Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells. (1990) (19)
- Differential drug sensitivity conferred by growth status detected in a mixed population of cycling and noncycling cells. (1990) (19)
- Effects of the polyamine analogues BE-4-4-4-4, BE-3-7-3, and BE-3-3-3 on the proliferation of three prostate cancer cell lines (1997) (18)
- Cryptosporidium parvum spermidine/spermine N1-acetyltransferase exhibits different characteristics from the host enzyme. (2007) (18)
- Trans-scleral delivery of polyamine analogs for ocular neovascularization. (2006) (18)
- Renal ornithine decarboxylase activity, polyamines, and compensatory renal hypertrophy in the rat. (1988) (18)
- Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047 (2017) (17)
- Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells (2005) (17)
- Time dependence of the potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity caused by alpha-difluoromethylornithine-induced polyamine depletion in 9L rat brain tumor cells. (1984) (17)
- Determination of carbamazepine in blood or plasma by high-pressure liquid chromatography. (1976) (17)
- Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues. (2004) (16)
- Differential response to 1,3‐bis (2‐chloroethyl)‐1‐nitrosourea in drug‐resistant and ‐sensitive 9L rat brain tumor cells pretreated with α‐difluoromethylornithine and 6‐thioguanine (1989) (16)
- Modification of Radiation-Induced Brain Injury by α-Difluoromethylornithine (1991) (16)
- Gene expression analysis of HCT116 colon tumor-derived cells treated with the polyamine analog PG-11047. (2009) (16)
- Effect of N1,N14‐bis‐(ethyl)‐homospermine (BE‐4–4‐4) on the growth of U‐251 MG and SF‐188 human brain tumor cells (1991) (16)
- Polyamines in clinical disorders. (1985) (16)
- Effect of α-Difluoromethylornithine on 1,3-Bis(2-chloroethyl)-1-nitrosourea and cis-Diamminedichloroplatinum(II) Cytotoxicity, DNA Interstrand Cross-Linking, and Growth in Human Brain Tumor Cell Lines in Vitro (1990) (15)
- Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells (1983) (15)
- Decreased cell kill of vincristine and methotrexate against 9L rat brain tumor cells in vitro caused by alpha-difluoromethylornithine-induced polyamine depletion. (1984) (14)
- α-Difluoromethylornithine Alters Calcium Signaling in Platelet-derived Growth Factor-stimulated A172 Brain Tumor Cells in Culture (1992) (14)
- Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase. (1984) (14)
- Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate. (1986) (13)
- Polyamines decrease Ca(2+) sensitivity of tension and increase rates of activation in skinned cardiac myocytes. (2000) (13)
- Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells. (1987) (13)
- Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. (2006) (13)
- Effects of dicyclohexylamine sulfate, a spermidine synthase inhibitor, in 9L rat brain tumor cells. (1985) (12)
- Liquid Chromatography in Clinical Analysis (1981) (12)
- Putrescine diffusion in cat brain and capillary permeability in rat brain: relation to CSF putrescine levels in brain tumor patients. (1981) (11)
- The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis-diaminedichloroplatinum (II) (CDDP) in human brain tumor cell lines. (1996) (11)
- Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival. (1993) (11)
- Determination of placental estriol in urine by gas-liquid chromatography, with equilenin as internal standard. (1977) (11)
- CSF polyamines. Potential as brain tumor markers. (1981) (11)
- Modification of uptake and antiproliferative effect of methylglyoxal bis(guanylhydrazone) by treatment with alpha-difluoromethylornithine in rodent cell lines with different sensitivities to methylglyoxal bis(guanylhydrazone). (1985) (10)
- Uremic polyamine dysmetabolism. (1978) (10)
- Role of p53/p21(Waf1/Cip1) in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells. (2005) (10)
- Improved liquid chromatographic determination of placental estriol in urine. (1978) (10)
- Therapeutic Evaluation of Polyamine Analogue Drug Candidates against Enterocytozoon bieneusi in a SCID Mouse Model (2009) (10)
- POL Y AMINES AS TARGETS FOR THERAPEUTIC INTERVENTION (1995) (10)
- Production of stable phenotypes from 9L rat brain tumor multicellular spheroids treated with 1,3‐bis(2‐chloroethyl)‐1‐nitrosourea (1992) (9)
- Liquid chromatography with fluorometric detection of unconjugated estriol in serum of pregnant women. (1983) (9)
- Changes in mitochondrial structure and function in 9l rat brain tumor cells treated in vitro with alpha-difluoromethylornithine, a polyamine biosynthesis inhibitor. (1983) (9)
- High-pressure liquid-chromatographic determination of 5-(4-hydroxyphenyl)-5-phenylhydantoin in humanurine. (1976) (9)
- Polyamine accumulation and vasogenic oedema in the genesis of late delayed radiation injury of the central nervous system (CNS). (1990) (9)
- Age-Related Abnormalities of Circulating Polyamines and Diamine Oxidase Activity in Cystic Fibrosis Heterozygotes and Homozygotes (1980) (9)
- Progressive Increase In Polyamine Levels In 9l Cells in vitro During the Cell Cycle: Comparison Between Cells Isolated By Centrifugal Elutriation and Cells Grown In Synchrony (2008) (9)
- Polyamine levels in CSF from patients with pituitary tumors or nonneoplastic pituitary disease. (1982) (9)
- Effects of fractionated radiation therapy on human brain tumor multicellular spheroids. (1993) (9)
- Failure to Demonstrate Desmosterol in Spinal Fluid of Brain Tumor Patients (1973) (9)
- The effects ofO6-benzylguanine and hypoxia on the cytotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea in nitrosourea-resistant SF-763 cells (2004) (9)
- Polyamine analogues: potent inducers of nucleosomal array oligomerization and inhibitors of yeast cell growth. (2007) (9)
- Polyamine–DNA Interactions: Possible Site of New Cancer Chemotherapeutic Intervention (1986) (8)
- Polyamine metabolism in synchronously growing mammalian cells (1976) (8)
- Some comments on anticonvulsant-drug monitoring by liquid chromatography. (1980) (8)
- Polyamines. The elusive cancer markers. (1982) (8)
- Role of detrapped electrons in the radiolysis of crystalline choline chloride (1971) (8)
- Filter elution analysis of the effect of alpha-difluoromethylornithine on X-ray-induced DNA damage in 9L cells. (1987) (8)
- Activities of dl-α-Difluoromethylarginine and Polyamine Analogues against Cryptosporidium parvum Infection in a T-Cell Receptor Alpha-Deficient Mouse Model (2007) (8)
- Relationship between heat sensitivity and polyamine levels after treatment with alpha-difluoromethylornithine (DFMO). (1986) (7)
- Biochemical markers of central nervous system tumors in cerebrospinal fluid. (1978) (7)
- Pharmacogenomics of the Polyamine Analog 3,8,13,18-tetraaza-10,11-[(E)-1,2-cyclopropyl] eicosane Tetrahydrochloride, CGC-11093, in the Colon Adenocarcinoma Cell Line HCT1161 (2006) (7)
- Survival, and Polyamine Levels in Seven Human Brain Tumor Cell Lines1 (1993) (7)
- Cholesterol in cerebrospinal fluid of brain tumor patients. (1973) (7)
- Reduction in cis-diamminedichloroplatinum(II)-induced cytotoxicity, sister chromatid exchange, and DNA interstrand cross-links in 9L cells treated with the polyamine biosynthesis inhibitor (2R,5R)-6-heptyne-2,5-diamine. (1989) (7)
- Potential uses of polyamine biosynthesis inhibitors in tumor therapy. (1984) (6)
- Cell proliferation and polyamine metabolism in 9L cells treated with (2R,5R)‐6‐heptyne‐2,5‐diamine or α‐difluoromethylornithine (1989) (6)
- K+ binding in the G-loop and water cavity facilitates Ba2+ movement in the Kir2.1 channel. (2009) (6)
- Clinical Correlations of Cerebrospinal Fluid Polyamine Levels (1983) (6)
- Modification of radiation-induced brain injury by alpha-difluoromethylornithine. (1991) (5)
- A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma (2020) (5)
- Effect of hypoxia on 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L cells. (1990) (5)
- Slowing proliferation in head and neck tumors: in vitro growth inhibitory effects of the polyamine analog BE-4-4-4-4 in human squamous cell carcinomas. (1995) (5)
- Polyamines and brain tumors. (1977) (5)
- Effect of alpha-difluoromethylornithine on 1,3-bis(2-chloroethyl)-1-nitrosourea and cis-diamminedichloroplatinum(II) cytotoxicity, DNA interstrand cross-linking, and growth in human brain tumor cell lines in vitro. (1990) (5)
- A phase I dose-escalation study of the polyamine analog PG-11047 in patients with advanced solid tumors (2020) (5)
- Source of error in cerebrospinal fluid protein determination with the Du Pont Automatic Clinical Analyzer. (1978) (5)
- Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines (2004) (5)
- Directions for polyamine research (1991) (5)
- Changes in the glutathione content of rat 9L cells induced by treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine. (1987) (4)
- Reduced transglutaminase-catalyzed cross-linking of exogenous amines to membrane proteins in sickle erythrocytes. (1985) (4)
- Spermine induces haemoglobin synthesis in murine erythroleukaemia cells. (1995) (4)
- Cell-cycle, phase-specific cell killing by carmustine in sensitive and resistant cells. (1988) (4)
- Measurementof Putrescine,Spermidine,and Sperminein Physiological Fluidsby Use of an AminoAcid Analyzer (1973) (4)
- CSF polyamines in childhood. (1983) (4)
- Radiopotentiation of human brain tumor cells by the spermine analog N1,N14-bis(ethyl)homospermine. (1994) (3)
- Theoretical Models of Spermine/DNA Interactions a (1986) (3)
- An approach to the use of polyamine inhibitors for cancer therapy. (1981) (3)
- Kinetics and distribution of tritiated putrescine in the domestic cat. (1979) (3)
- Effect of polyamines on hemoglobin and globin chain synthesis. (1985) (3)
- The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells. (1995) (3)
- SL‐11158, a Synthetic Oligoamine, Inhibits Polyamine Metabolism of Encephalitozoon cuniculi (2001) (3)
- Polyamine depletion and drug-induced chromosomal damage: new results. (1992) (3)
- Hypnotics and Sedatives (1981) (2)
- alpha-Difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture. (1992) (2)
- Effect of spermine on sperm capacitation of guinea pig in vitro. (1992) (2)
- Cell proliferation and polyamine metabolism in 9L cells treated with (2R,5R)-6-heptyne-2,5-diamine or alpha-difluoromethylornithine. (1989) (2)
- Urinary polyamine levels in cancer patients treated with D,L‐α‐Difluoromethylornithine, an inhibitor of polyamine biosynthesis (1989) (1)
- Organic Acids by Ion Chromatography (1981) (1)
- Abstract 4877: Polyamine analogues modulate gene expression by inhibiting KDM1/LSD1 and altering chromatin structure in human breast cancer cells (2010) (1)
- Chapter 10:The Design and Development of Polyamine-Based Analogs with Epigenetic Targets (2011) (1)
- CSF putrescine levels. The enzymatic-isotopic method vs liquid chromatography. (1981) (1)
- Measurement of mono conjugated di conjugated and unconjugated bilirubin ix alpha in normal and hyper bilirubinemic serum (1979) (1)
- The correlation of PHA induced polyamine changes in human lymphocytes with tritiated thymidine incorporation. (1974) (1)
- Specificity and Binding in Polyamine/Nucleic Acid Interactions (2021) (1)
- Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells. (1994) (1)
- 12 – Modification of the Cytotoxicity of DNA-Directed Chemotherapeutic Agents by Polyamine Depletion (1988) (1)
- Mechanisms of heat protection by cycloheximide or puromycin: Involvement of polyamines? (1991) (1)
- Polyamines: relation to brain tumor therapy and monitoring. (1981) (1)
- Clinical liquid chromatography (1984) (1)
- K + binding in the G-loop and water cavity facilitates Ba 2+ movement in the (2009) (1)
- Measurement of lactate extraction ratio by centrifugal analyzer to assess myocardial ischemia. (1977) (1)
- Determinationof OrganicAcidsin BiologicalFluidsby IonChromatography : PlasmaLactateand Pyruvateand UrinaryVanillylmandelicAcid (2004) (0)
- Correction (2000) (0)
- [Polyamines as biomechanical markers in cancer and polyamine inhibitors efficacy in the treatment of malignant tumors]. (1983) (0)
- Activities of DL - (cid:2) -Difluoromethylarginine and Polyamine Analogues against Cryptosporidium parvum Infection in a T-Cell Receptor Alpha-Deficient Mouse Model (cid:1) (2007) (0)
- Abstract 4884: Polyamine analogues in combination with DFMO inhibits lysine-specific demethylase 1 and induces re-expression of aberrantly silenced genes (2010) (0)
- SimultaneousLiquid-ChromatographicDeterminationof Zinc Protoporphyrin IX , ProtoporphyrinIX , and Coproporphyrinin Whole Blood (2004) (0)
- Growth Regulatory Effects of Depletion Are Dissociable in Cells Cyclic AMP and Cultured Mouse Polyamine Lymphoma (2003) (0)
- Abstract #LB-205: PG11047, A Polyamine Analog, Induces Potent Antitumor Activity in a Preclinical Model of Non-Small Cell Lung Cancer in Combination with Cisplatin. (2009) (0)
- Faliure to demonstrate desmosterol in spinal fluid of brain tumor patients. (1973) (0)
- Abstracts for the Tenth International Conference on Brain Tumour Research and Therapy (2005) (0)
- Compositions et méthodes de combinaisons d'oligoamines avec la 2-difluorométhylornithine (dfmo) (2011) (0)
- SimultaneousDeterminationof Phosphatidyiglycerolandthe Lecithin / SphingomyelinRatioin AmnioticFluid (2004) (0)
- Potentially nephrotoxic conjugated amines in the urine of patients with hepatic failure (1978) (0)
- Estrogenic regulation of polyamine analogue cytotoxicity in human breast cancer cells (2005) (0)
- Modulation of Histone H3K4 and H3K27 Methylation Levels Via Pharmacological Inhibition of LSD1 and Degradation of the EZH2-Containing Polycomb Repressive Complex 2 Stimulates ATRA-Mediated Differentiation of AML Cells. (2009) (0)
- Cell Cycle Polyamine Content of AKR Leukemic Cells in Relation to the Updated (2006) (0)
- ImprovedLiquidChromatographicDeterminationof PlacentalEstriol in Urine (2004) (0)
- AIDS-Associated Infection Microsporidiosis, an Opportunistic the Treatment of Experimental Novel Synthetic Polyamines Are Effective in (2014) (0)
- Reduction in m-I)iaininiiicd Cytotoxicity, Sister Chromatid Exchange, and DNA Interstrand Cross-Links in 9L Cells Treated with the Polyamine Biosynthesis Inhibitor (2/?,5/?)-6-Heptyne-2,5-diamine' (2006) (0)
- Decreased cytotoxicity of 1-beta-D-arabinofuranosylcytosine in 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine in vitro. (1983) (0)
- Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells (2011) (0)
- Abstract LB-97: Combination of a conformationally restricted polyamine analogue with DNA methyltransferase or histone deacetylase inhibition induces synergistic reexpression of aberrantly silenced tumor suppressor genes (2010) (0)
- 4132 POSTER NMYC-Amplified Neuroblastoma Succumb to Treatment With a Polyamine Analogue (2011) (0)
- Determinationof Acetaminophenand Phenacetinin Plasmaby High-PressureLiquidChromatography (2004) (0)
- Fluorometric Liquid-ChromatographicDeterminationof Serum Cortisol (1981) (0)
- Separation of polyamines by polyacrylamide gel exchange chromatography. (1979) (0)
- L1210 Murine Leukemia Cells -(9-Acridinylamino)methanesulfon-m-anisidide in ' Produced by 4 Biosynthesis, on the Topoisomerase II-mediated DNA Scission Effect of Difluoromethylornithine, an Inhibitor of Polyamine (2013) (0)
- Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia (2011) (0)
- Correction: Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047 (2017) (0)
- Chromatography, withEquilenin as InternalStandard (1977) (0)
- Nucleic Acids Research New DNA polymorphism: evidence for a low salt, left-handed form of poly(dG-m'dC) (2005) (0)
- 911 GROWTH PROCESSES DURING EARLY MAMMALIAN DEVELOPMENT: FLUCTUATING POLYAMTNE CONCENTRATIONS IN THE PREIMFLANTATION MOUSE EMBRYO (1978) (0)
- Common Sethtives and Hypnotics in Serum (1978) (0)
- SimultaneousMeasurementof Phenobarbital, Diphenyihydantoin, and Primidonein Bloodby High-PressureLiquidChromatography (1976) (0)
- Specialty Conference Polyamines in Clinical Disorders (2005) (0)
- Polyamine Analogs Suppress Choroidal Neovascularization(CNV) (2004) (0)
- Biological Markers of the Tumors of the Central Nervous System (1981) (0)
- EXA/LEAP 2008 : proceedings of the international conference on exotic atoms (EXA 2008) and the 9th international conference on low energy antiproton physics (LEAP 2008) held in Vienna, Austria, 15-19 September 2008 (2010) (0)
- Effect of Hypoxia on l , 3-Bis ( 2-chloroethyl )-l-nitrosourea Cytotoxicity in 9 L Cells 1 (2006) (0)
- Interactions of Polyamine Analogs With Chromatin and the Relationship of Polyamine Analog Growth Inhibitory Activity to Extracellular Matrix Control of the Uveal Melanoma Cell Phenotype (2007) (0)
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