Lelio Orci

Q: What Schools Are Affiliated With Lelio Orci

Lelio Orci is affiliated with the following schools: McGill University, Tohoku University, Massachusetts Institute of Technology, University of Copenhagen, University of Geneva, University of Texas Southwestern Medical Center, University of Pennsylvania, Heidelberg University

Lelio Orci's AcademicInfluence.com Rankings

Lelio Orci

Biology

#2009

World Rank

#3248

Historical Rank

Cell Biology

#36

World Rank

#40

Historical Rank

biology Degrees

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Biology

Lelio Orci's Degrees

PhD Cell Biology University of Geneva

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Lelio Orci's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum (1994) (1310)
Lipotoxic heart disease in obese rats: implications for human obesity. (2000) (1287)
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor (1991) (1159)
Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. (1978) (1005)
Coat Proteins and Vesicle Budding (1996) (967)
Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis (2001) (961)
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. (1992) (904)
Molecular dissection of the secretory pathway (1992) (902)
Bi-directional protein transport between the ER and Golgi. (2004) (887)
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic (1991) (835)
Basic fibroblast growth factor induces angiogenesis in vitro. (1986) (823)
Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. (1986) (671)
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. (1991) (647)
In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices (1983) (637)
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes (1998) (628)
The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). (1982) (605)
Studies of the Diabetogenic Action of Streptozotocin.∗ (1967) (597)
Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts: implications for wound healing. (1988) (557)
THE ESSENTIAL ROLE OF GLUCAGON IN THE PATHOGENESIS OF DIABETES MELLITUS (1975) (542)
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein (1991) (538)
New Perspectives on the Microvasculature of the Islets of Langerhans in the Rat (1982) (538)
Lipid homeostasis, lipotoxicity and the metabolic syndrome. (2010) (535)
Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors (1991) (501)
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles (2003) (495)
The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes (1990) (483)
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle (2005) (481)
Tumor-promoting phorbol esters induce angiogenesis in vitro (1985) (465)
A new type of coated vesicular carrier that appears not to contain clathrin: Its possible role in protein transport within the Golgi stack (1986) (464)
Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene (1990) (449)
Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro (1990) (448)
Involvement of GTP-binding “G” proteins in transport through the Golgi stack (1987) (446)
Diseases of liporegulation: new perspective on obesity and related disorders (2001) (442)
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins (1982) (439)
Regulation of fatty acid homeostasis in cells: novel role of leptin. (1999) (439)
FUNCTIONAL SUBDIVISION OF ISLETS OF LANGERHANS AND POSSIBLE ROLE OF D CELLS (1975) (436)
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles (1997) (436)
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack (1989) (432)
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. (1997) (427)
Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes. (1989) (381)
Lipoapoptosis: its mechanism and its diseases. (2002) (367)
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack (1988) (366)
Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion (1972) (357)
Somatostatinoma syndrome. Biochemical, morphologic and clinical features. (1979) (355)
A view of acidic intracellular compartments (1988) (350)
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. (1993) (337)
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. (2000) (325)
Biphasic Effect of Transforming Growth Factor-β1 on in Vitro Angiogenesis (1993) (324)
Insulin within islets is a physiologic glucagon release inhibitor. (1984) (320)
Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles (1986) (319)
Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles (1987) (319)
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments (1994) (312)
Quantitative immunocytochemical localization of pancreatic secretory proteins in subcellular compartments of the rat acinar cell. (1980) (310)
Dynamics of the COPII coat with GTP and stable analogues (2001) (304)
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. (1978) (302)
Stepwise assembly of functionally active transport vesicles (1993) (299)
Macro- and Micro-Domains in the Endocrine Pancreas (1982) (296)
Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans (1982) (293)
Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells (1987) (291)
Upregulation of urokinase receptor expression on migrating endothelial cells (1993) (291)
Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking (2006) (276)
Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes. (1976) (271)
Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system (1984) (271)
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi- derived COP-coated vesicles (1993) (271)
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast (1995) (269)
Diabetes and apoptosis: lipotoxicity (2009) (269)
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. (1991) (266)
Direct identification of prohormone conversion site in insulin-secreting cells (1985) (263)
Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. (1987) (263)
Endocrine pancreas: three-dimensional reconstruction shows two types of islets of langerhans. (1979) (261)
Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. (2007) (260)
THE ENDOCRINE CELLS IN THE EPITHELIUM OF THE GASTROINTESTINAL MUCOSA OF THE RAT (1969) (257)
The trans-most cisternae of the Golgi complex: A compartment for sorting of secretory and plasma membrane proteins (1987) (256)
Glucagon and the A cell: physiology and pathophysiology (second of two parts). (1981) (251)
Dissection of a single round of vesicular transport: Sequential intermediates for intercisternal movement in the Golgi stack (1989) (242)
Physiology and pathophysiology of glucagon. (1976) (240)
Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats. (1999) (239)
Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. (1995) (238)
Paracrinology of islets and the paracrinopathy of diabetes (2010) (238)
Rapid transformation of white adipocytes into fat-oxidizing machines (2004) (236)
A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding (1996) (233)
Angiogenesis: a paradigm for balanced extracellular proteolysis during cell migration and morphogenesis. (1996) (226)
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. (1992) (224)
Glucagon: role in the hyperglycemia of diabetes mellitus. (1975) (224)
TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro. (1994) (220)
Lipotoxic diseases of nonadipose tissues in obesity (2000) (216)
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol (1993) (215)
Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells. (1992) (214)
Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. (1981) (213)
Insulin, glucagon, and somatostatin secretion in the regulation of metabolism. (1978) (212)
Embryogenesis of the Human Pancreatic Islets: A Light and Electron Microscopic Study (1972) (208)
Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains. (1989) (205)
Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study (2012) (204)
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes. (1998) (201)
Intracellular translocation of iodine-125-labeled insulin: direct demonstration in isolated hepatocytes. (1978) (201)
A role for the microtubular system in the release of very low density lipoproteins by perfused mouse livers. (1973) (199)
Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetes (1990) (198)
Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. (1991) (196)
STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum (2009) (195)
Pancreatic polypeptide and glucagon : non-random distribution in pancreatic islets. (1976) (191)
In vivo assembly of tight junctions in fetal rat liver (1975) (190)
Membrane particle changes attending the acrosome reaction in guinea pig spermatozoa (1977) (189)
Collagen matrix promotes reorganization of pancreatic endocrine cell monolayers into islet-like organoids (1983) (189)
Endothelial fenestral diaphragms: a quick-freeze, deep-etch study (1985) (189)
Differential expression of gap junction connexins in endocrine and exocrine glands. (1993) (188)
Fatty acyl-coenzyme a is required for budding of transport vesicles from Golgi cisternae (1989) (185)
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3 (2002) (185)
The genetic basis of a craniofacial disease provides insight into COPII coat assembly. (2007) (183)
Incomplete Processing of Proinsulin to Insulin Accompanied by Elevation of Des-31,32 Proinsulin Intermediates in Islets of Mice Lacking Active PC2* (1998) (178)
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins (1993) (175)
Evidence for the D-cell of the pancreas secreting somatostatin. (1975) (169)
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes (2004) (169)
Homologous but not heterologous contact increases the insulin secretion of individual pancreatic B-cells. (1989) (165)
Identification of glucagon in the gastrointestinal tract. (1975) (165)
Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivo. (1987) (163)
Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion (1979) (162)
Glucagon and the A cell: physiology and pathophysiology (first two parts). (1981) (162)
Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts (1982) (160)
Severe Defect in Proglucagon Processing in Islet A-cells of Prohormone Convertase 2 Null Mice* (2001) (159)
Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia. (1990) (156)
Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes. (1994) (156)
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes (1992) (156)
Alteration of Islet Cell Populations in Spontaneously Diabetic Mice (1978) (154)
Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity. (2005) (151)
Lst1p and Sec24p Cooperate in Sorting of the Plasma Membrane Atpase into Copii Vesicles in Saccharomyces cerevisiae (2000) (148)
Glucagon release induced by pancreatic nerve stimulation in the dog. (1973) (146)
Synergistic effect of hyaluronan oligosaccharides and vascular endothelial growth factor on angiogenesis in vitro. (1996) (145)
Paracrine induction of angiogenesis in vitro by Swiss 3T3 fibroblasts. (1993) (142)
Sec16p potentiates the action of COPII proteins to bud transport vesicles (2002) (142)
Role of Microtubules in Lipoprotein Secretion by the Liver (1973) (142)
Movement of proteins through the Golgi stack: a molecular dissection of vesicular transport 1 (1990) (141)
En bloc incorporation of coatomer subunits during the assembly of COP- coated vesicles [published erratum appears in J Cell Biol 1994 Jul;126(2):589] (1994) (139)
Morphological changes of the 3T3-L1 fibroblast plasma membrane upon differentiation to the adipocyte form. (1983) (139)
A clathrin-coated, golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin (1984) (138)
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome (2008) (135)
Coordination of COPII vesicle trafficking by Sec23. (2008) (134)
Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. (1994) (134)
Sec24 Proteins and Sorting at the Endoplasmic Reticulum* (1999) (134)
A Quantitative Immunofluorescent Study of the Endocrine Cell Populations in the Developing Human Pancreas (1983) (133)
Freeze-fracture of membrane fusions during exocytosis in pancreatic B- cells (1977) (133)
Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast (2006) (132)
Vesicles on strings: morphological evidence for processive transport within the Golgi stack. (1998) (131)
Human endothelial cell cultures: Phenotypic modulation by leukocyte interleukins (1985) (130)
ROLE OF MICROTUBULES IN THE PHASIC PATTERN OF INSULIN RELEASE * (1975) (129)
Phorbol ester induces cultured endothelial cells to invade a fibrin matrix in the presence of fibrinolytic inhibitors (1987) (129)
125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. (1978) (128)
Monolayer cell culture of neonatal rat pancreas: light microscopy and evidence for immunoreactive insulin synthesis and release. (1972) (128)
Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. (1990) (128)
A morphological basis for intercellular communication between alpha- and beta-cells in the endocrine pancreas. (1975) (128)
Quantitative electron microscopic autoradiography of insulin, glucagon, and somatostatin binding sites on islets. (1982) (128)
Development of insulin and glucagon binding and the adenylate cyclase response in liver membranes of the prenatal, postnatal, and adult rat: evidence of glucagon "resistance". (1976) (127)
Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell (1984) (127)
Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography. (1979) (126)
TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes. (1995) (126)
Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes. (1975) (124)
Localization of the vitamin D-dependent calcium-binding protein in mammalian kidney. (1982) (124)
Plasminogen activator inhibitor‐1 is induced in migrating endothelial cells (1992) (123)
Possible Roles of the Pancreatic D-cell in the Normal and Diabetic States (1977) (123)
The condensing vacuole of exocrine cells is more acidic than the mature secretory vesicle (1987) (122)
Anterograde flow of cargo across the golgi stack potentially mediated via bidirectional "percolating" COPI vesicles. (2000) (122)
Adequate connexin-mediated coupling is required for proper insulin production (1995) (119)
Cloning and functional characterization of mammalian homologues of the COPII component Sec23. (1996) (118)
In vitro angiogenic and proteolytic properties of bovine lymphatic endothelial cells. (1994) (117)
Junctional communication is induced in migrating capillary endothelial cells (1989) (116)
Surface structure of the COPII-coated vesicle (2001) (116)
Megavesicles Implicated in the Rapid Transport of Intracisternal Aggregates across the Golgi Stack (2000) (115)
Monolayer cell culture of neonatal rat pancreas: an ultrastructural and biochemical study of functioning endocrine cells. (1973) (114)
Pancreatic immunoreactive somatostatin release. (1977) (113)
beta′‐COP, a novel subunit of coatomer. (1993) (112)
Absence of filipin-sterol complexes from large coated pits on the surface of culture cells. (1979) (112)
Occurrence of low density lipoprotein receptors within large pits on the surface of human fibroblasts as demonstrated by freeze-etching. (1978) (109)
Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis. (1993) (108)
A v-SNARE implicated in intra-Golgi transport (1996) (108)
Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum (1995) (106)
Phorbol esters induce angiogenesis in vitro from large‐vessel endothelial cells (1987) (106)
Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. (1992) (106)
Glucagon and glicentin immunoreactivity are topologically segregated in the α granule of the human pancreatic A cell (1980) (106)
Exocrine pancreas: evidence for topographic partition of secretory function (1975) (106)
ADP-ribosylation factor and coatomer couple fusion to vesicle budding (1994) (105)
Immunocytochemistry of vitamin D-dependent calcium binding protein in chick pancreas: exclusive localization. (1982) (103)
Specific plasma membrane differentiations in the cells of the kidney collecting tubule. (1975) (103)
A freeze-etch study of the tight junctions of the rat kidney tubules. (1974) (102)
Generation and characterization of telomerase-transfected human lymphatic endothelial cells with an extended life span. (2004) (101)
Glicentin immunoreactive cells: their relationship to glucagon-producing cells. (1979) (100)
Exocytosis-Endocytosis Coupling in the Pancreatic Beta Cell (1973) (100)
The topography of electrical synchrony among beta-cells in the mouse islet of Langerhans. (1984) (100)
Internalized insulin receptors are recycled to the cell surface in rat hepatocytes. (1982) (99)
Leukemia inhibitory factor (LIF) inhibits angiogenesis in vitro. (1995) (99)
Vasopressin stimulates formation of coated pits in rat kidney collecting ducts (1983) (98)
Vitamin D--dependent calcium binding protein: immunocytochemical localization in chick kidney. (1981) (97)
Angiogenesis-regulating cytokines: activities and interactions. (1996) (97)
Leukocyte interleukins induce cultured endothelial cells to produce a highly organized, glycosaminoglycan-rich pericellular matrix (1984) (97)
PANCREATIC-POLYPEPTIDE-RICH REGIONS IN HUMAN PANCREAS (1978) (97)
Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles* (2005) (97)
Increase in membrane cholesterol: A possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells (1984) (97)
Pronase Effect on Pancreatic Beta Cell Secretion and Morphology (1973) (96)
Clathrin-immunoreactive sites in the Golgi apparatus are concentrated at the trans pole in polypeptide hormone-secreting cells. (1985) (95)
In Vivo Modulation of Gap Junctions and Dye Coupling Between B-Cells of the Intact Pancreatic Islet (1983) (95)
Dynamics of insulin release and microtubular-microfilamentous system. I. Effect of cytochalasin B. (1973) (94)
Ultrastructural analysis of crystalloid endoplasmic reticulum in UT-1 cells and its disappearance in response to cholesterol. (1983) (93)
Pancreatic steatosis: harbinger of type 2 diabetes in obese rodents (2010) (92)
Changes in somatostatin concentration in pancreas and other tissues of streptozotocin diabetic rats. (1978) (92)
Modulation of bovine microvascular endothelial cell proteolytic properties by inhibitors of angiogenesis (1994) (90)
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack. (2004) (90)
Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex (1996) (90)
Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin. (2007) (89)
Reduced beta-cell glucose transporter in new onset diabetic BB rats. (1990) (89)
Traffic COPs and the formation of vesicle coats. (1996) (88)
Circulating somatostatin acts on the islets of Langerhans by way of a somatostatin-poor compartment. (1982) (86)
p24 and p23, the major transmembrane proteins of COPI‐coated transport vesicles, form hetero‐oligomeric complexes and cycle between the organelles of the early secretory pathway (1999) (86)
Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles. (1982) (85)
GRANULOLYSIS IN A CELLS OF ENDOCRINE PANCREAS IN SPONTANEOUS AND EXPERIMENTAL DIABETES IN ANIMALS (1968) (85)
Exclusion of Golgi Residents from Transport Vesicles Budding from Golgi Cisternae in Intact Cells (2000) (85)
Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes (1982) (84)
Glucagon-like Polypeptides in Canine Brain (1979) (84)
In vivo induction of tight junction proliferation in rat liver (1976) (84)
Direct communication of homologous and heterologous endocrine islet cells in culture (1982) (84)
Immunohistochemical localization of carbonic anhydrase in postnatal and adult rat kidney. (1983) (84)
The insulin factory: a tour of the plant surroundings and a visit to the assembly line (1985) (83)
Insulin Release by Emiocytosis: Demonstration with Freeze-Etching Technique (1973) (83)
Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins. (2005) (83)
Identification of glucagon-producing cells (A cells) in dog gastric mucosa (1976) (83)
Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells (1987) (82)
The microanatomy of the islets of Langerhans. (1976) (82)
FITC-protein A-gold complex for light and electron microscopic immunocytochemistry. (1980) (82)
Selective localization of calcium-binding protein in human brainstem, cerebellum and spinal cord (1986) (82)
Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide (1979) (82)
Regional distribution of N-acetyl-D-galactosamine residues in the glycocalyx of glomerular podocytes (1983) (82)
Potassium depletion and hypertonic medium reduce “non‐coated” and clathrin‐coated pit formation, as well as endocytosis through these two gates (1989) (81)
Application of the protein A-gold technique for electron microscopic demonstration of polypeptide hormones. (1981) (80)
Blockage of cell-to-cell communication within pancreatic acini is associated with increased basal release of amylase (1986) (80)
Pancreatic polypeptide: A possible role in the regulation of food intake in the mouse. Hypothesis (1977) (79)
Gap junction development is correlated with insulin content in the pancreatic B cell. (1980) (79)
Vascular endothelial growth factor is increased in devascularized rat islets of Langerhans in vitro. (1997) (79)
Morphology and metabolism of an aortic intima-media preparation in which an intact endothelium is preserved. (1976) (77)
Immunocytochemical localization of the vitamin D-dependent calcium binding protein in chick duodenum (1982) (77)
pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle (1994) (77)
Morphological changes in tight junctions of Necturus maculosus proximal tubules undergoing saline diuresis (1976) (76)
Chondrocytes inhibit endothelial sprout formation in vitro: Evidence for involvement of a transforming growth factor‐beta (1991) (76)
Intracellular membrane fusion. (1991) (76)
GLUT2 Expression and Function in β-cells of GK rats with NIDDM: Dissociation Between Reductions in Glucose Transport and Glucose-Stimulated Insulin Secretion (1993) (75)
Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases (1988) (73)
zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly (1993) (73)
Membrane-Associated Particles: Increase at Sites of Pinocytosis Demonstrated by Freeze-Etching (1973) (73)
Patterns of calcium localization in pancreatic endocrine cells. (1976) (71)
Glucagon and the A cells. (2010) (71)
The Stimulus-Secretion Coupling of Glucose-Induced Insulin Release: IX. The Participation of the Beta Cell Web (1972) (70)
Parathyroid hormone biosynthesis. Correlation of conversion of biosynthetic precursors with intracellular protein migration as determined by electron microscope autoradiography (1979) (70)
A resident Golgi protein is excluded from peri-Golgi vesicles in NRK cells (2002) (69)
Gastric A-cell function in insulin-deprived depancreatized dogs. (1976) (68)
Somatostatin: widespread abnormality in tissues of spontaneously diabetic mice. (1977) (68)
Insulin and Glucagon Release from Monolayer Cell Cultures of Pancreas from Newborn Rats (1973) (67)
Motile events in pancreatic endocrine cells. (1979) (67)
Nonrandom distribution of gap junctions between pancreatic beta-cells. (1980) (66)
Secretion-dependent uptake of extracellular fluid by the rat neurohypophysis (1974) (66)
Hepatic Autophagy in Uncontrolled Experimental Diabetes and Its Relationships to Insulin and Glucagon (1974) (66)
Dynamics of insulin release and microtubular-microfilamentous system (1974) (65)
Cell contacts in human islets of Langerhans. (1975) (65)
Surface redistribution of 125I-insulin in cultured human lymphocytes (1981) (64)
Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation. (1992) (64)
Secretion-related uptake of horseradish peroxidase in neurohypophysial axons (1976) (64)
Hypothesis: physiologic role of pancreatic somatostatin and the contribution of D-cell disorders to diabetes mellitus. (1977) (64)
Vascular outgrowths from tissue explants embedded in fibrin or collagen gels: a simple in vitro model of angiogenesis. (1985) (64)
Membrane infrastructure in Urinary Tubules (1981) (63)
Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump. (1987) (63)
A comparative study of freeze-etch replicas and thin sections of rat liver. (1971) (63)
Gap junctional coupling modulates secretion of exocrine pancreas. (1987) (62)
Binding, internalization, and lysosomal association of 125I-human growth hormone in cultured human lymphocytes: a quantitative morphological and biochemical study (1980) (62)
Intracellular localization of 125I-labeled insulin in hepatocytes from intact rat liver. (1979) (61)
Two steps of insulin receptor internalization depend on different domains of the beta-subunit [published erratum appears in J Cell Biol 1993 Nov;123(4):1047] (1993) (61)
Spontaneous hyperglycemia and-or obesity in laboratory rodents: an example of the possible usefulness of animal disease models with both genetic and environmental components. (1971) (61)
Roles of Hepatocyte Growth Factor/Scatter Factor and Transforming Growth Factor-β1 in Mammary Gland Ductal Morphogenesis (1998) (61)
Vasopressin stimulates endocytosis in kidney collecting duct principal cells. (1988) (60)
Ultrastructure and secretory cycle of the gastrin-producing cell (2004) (60)
Metabolic coupling between cultured pancreatic b-cells. (1981) (60)
Polypeptide hormone degradation and receptor regulation are coupled to ligand internalization. A direct biochemical and morphologic demonstration. (1981) (59)
Self‐assembly of minimal COPII cages (2003) (59)
Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth. (1995) (58)
Decreased pancreatic somatostatin (SRIF) concentration in spontaneously diabetic mice. (1976) (58)
Hypothesis: Single and Chain Release of Insulin Secretory Granules Is Related to Anionic Transport at Exocytotic Sites (1980) (58)
Role of microtubules in the synthesis, conversion, and release of (pro)insulin. A biochemical and radioautographic study in rat islets. (1979) (57)
Effects of calcium ionophores on the synthesis and release of parathyroid hormone. (1977) (57)
A freeze-fracture study of membrane events during neurohypophysial secretion (1978) (57)
Efficient targeting to storage granules of human proinsulins with altered propeptide domain (1988) (56)
Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution. (1995) (56)
"BFA bodies": a subcompartment of the endoplasmic reticulum. (1993) (56)
Functional and Morphologic Characterization of Human Insulinomas (1983) (55)
Junctions in developing human and rat kidney: a freeze-fracture study. (1976) (55)
Nonconverted, amino acid analog-modified proinsulin stays in a Golgi- derived clathrin-coated membrane compartment (1984) (55)
INSTABILITY OF PANCREATIC ENDOCRINE CELL POPULATIONS THROUGHOUT LIFE (1979) (55)
Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study. (1980) (54)
Lectin-gold cytochemistry reveals intercalated cell heterogeneity along rat kidney collecting ducts. (1985) (54)
RABBIT SCIATIC NERVE FASCICLE AND‘ENDONEURIAL’PREPARATIONS FOR IN VITRO STUDIES OF PERIPHERAL NERVE GLUCOSE METABOLISM (1979) (53)
Lectin-gold labeling of glycoconjugates in normal and Brattleboro rat papilla: effect of vasopressin. (1988) (53)
Colchicine-binding protein of the liver. Its characterization and relation to microtubules (1975) (52)
Two transgenic approaches to define the cell lineages in endocrine pancreas development (1998) (51)
Intracellular transport and sorting of mutant human proinsulins that fail to form hexamers (1991) (50)
The role of glucagon in the endogenous hyperglycemia of diabetes mellitus. (1977) (50)
Coatomer-rich endoplasmic reticulum. (1994) (49)
STIM1L traps and gates Orai1 channels without remodeling the cortical ER (2015) (49)
Morphological changes of the adipose cell plasma membrane during lipolysis (1977) (48)
The "coat" of kidney intercalated cell tubulovesicles does not contain clathrin. (1986) (48)
Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas. (1985) (48)
Immunolocalization of betagranin: a chromogranin A-related protein of the pancreatic B-cell. (1988) (48)
Human islet cell tumor storing pancreatic polypeptide: a light and electron microscopic study. (1978) (48)
ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi (1997) (48)
Stimulation of pancreatic immunoreactive somatostatin (IRS) release by glucagon [proceedings]. (1976) (48)
Localization of pancreastatin immunoreactivity in porcine endocrine cells. (1988) (48)
Response of pancreatic immunoreactive somatostatin to arginine. (1976) (47)
Nonclathrin‐coated vesicles are involved in endocytosis in kidney collecting duct intercalated cells (1987) (47)
Structural evidence for glucagon producing cells in the intestinal mucosa of the rat (2005) (47)
Role of intracellular calcium and protein kinase C in the endocytosis of transferrin and insulin by HL60 cells (1986) (46)
Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited. (1996) (44)
Budding vesicles in living cells. (1996) (44)
Selective binding of somatostatin-14 and somatostatin-28 to islet cells revealed by quantitative electron microscopic autoradiography. (1987) (44)
Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes (2010) (44)
The insulin factory. (1988) (44)
Structural coupling between pancreatic islet cells (1973) (43)
Binding and internalization of somatostatin, insulin, and glucagon by cultured rat islet cells. (1989) (43)
A study on the permeability barriers between Disse's space and the bile canaliculus. (1969) (43)
Molecular heterogeneity and cellular localization of carboxypeptidase H in the islets of Langerhans. (1991) (43)
A portrait of the pancreatic B-Cell (1974) (43)
Insulin receptors and bioresponses in a human liver cell line (Hep G-2). (1985) (43)
FENESTRAE IN THE ROUGH ENDOPLASMIC RETICULUM OF THE EXOCRINE PANCREATIC CELLS (1972) (43)
Insulin-induced receptor loss in the cultured human lymphocyte: quantitative morphological perturbations in the cell and plasma membrane. (1979) (42)
Gap junctions and cell-to-cell coupling in endocrine glands (1984) (42)
[Ultrastructural events associated with the action of tolbutamide and glybenclamide on pancreatic B-cells in vivo and in vitro]. (1969) (42)
Monolayer Cultures of Adult Pancreatic Islet Cells on Osmotically Disrupted Fibroblasts (1980) (41)
Elevated Portal and Peripheral Blood Concentration of Immunoreactive Somatostatin in Spontaneously Diabetic (BBL) Wistar Rats: Suppression With Insulin (1980) (41)
Somatostatin secretion from monolayer cultures of neonatal rat pancreas. (1979) (41)
Isolation of EpH4 mammary epithelial cell subpopulations which differ in their morphogenetic properties (1998) (41)
Down-regulation and recycling of insulin receptors. Effect of monensin on IM-9 lymphocytes and U-937 monocyte-like cells. (1984) (41)
The insulin receptor of a human monocyte-like cell line: characterization and function. (1984) (41)
SEC23-SEC31 the Interface Plays Critical Role for Export of Procollagen from the Endoplasmic Reticulum (2012) (40)
Rod‐shaped particles in the plasma membrane of the mitochondria‐rich cell of amphibian epidermis (1978) (40)
The role of glucagon in diabetes. (1977) (40)
Dispersed adult rat pancreatic islet cells in culture: A, B, and D cell function. (1984) (40)
Effect of chlorpromazine (CPZ) on insulin release in vivo and in vitro in the rat. (1973) (40)
The stereological analysis of the fine structure of the “micropinocytosis vermiformis” in Kupffer cells of the rat (1968) (39)
Internalization of polypeptide hormones (1980) (39)
MitoNEET-dependent formation of intermitochondrial junctions (2017) (39)
Immunocytochemical localization of prosomatostatin fragments in maturing and mature secretory granules of pancreatic and gastrointestinal D cells. (1983) (39)
Evidence for polarization of plasma membrane domains in pancreatic endocrine cells (1985) (39)
Ultrastructural studies of the hyperplastic islets of langerhans of spiny mice (acomys cahirinus) before and during the development of hyperglycemia (1967) (38)
Actin in pancreatic islet cells. (1974) (38)
Intercellular junctions in podocytes of the nephrotic glomerulus as seen with freeze-fracture. (1975) (38)
Use of a synthetic peptide antigen to generate antisera reactive with a proteolytic processing site in native human proinsulin: demonstration of cleavage within clathrin-coated (pro)secretory vesicles. (1987) (37)
Membrane ultrastructure in urinary tubules. (1981) (37)
i-SNAREs (2004) (37)
TGF-beta1 induces morphogenesis of branching cords by cloned mammary epithelial cells at subpicomolar concentrations. (1996) (37)
Microheterogeneity of protein and sterol content in kidney podocyte membrane (1981) (36)
A Specialized Membrane Junction between Nerve Endings and B‐Cells in Islets of Langerhans (1973) (36)
ON THE ROLE OF CYCLIC AMP IN INSULIN RELEASE: I. OVERALL EFFECTS IN CULTURED FETAL RAT PANCREAS * (1971) (36)
Studies of the physiology and pathophysiology of the pancreatic D cell. (1978) (36)
Heterogeneity of toad bladder granular cell luminal membranes. Distribution of filipin-sterol complexes in freeze-fracture. (1980) (36)
1 – THE STRUCTURE OF THE JUXTAGLOMERULAR COMPLEX* (1971) (35)
Redistribution of 125I-Insulin on the Surface of Rat Hepatocytes as a Function of Dissociation Time (1985) (35)
Effects of Intraportal Islet Transplantation on the Transplanted Tissue and the Recipient Pancreas: I. Functional Studies (1980) (35)
LLC‐PK1 cysts: A model for the study of epithelial polarity (1985) (35)
Islet cell membrane alteration by diabetogenic drugs. (1976) (34)
(Pro)insulin associates with Golgi membranes of pancreatic B cells. (1984) (34)
The insulin cell: its cellular environment and how it processes (pro)insulin. (1986) (34)
The effects of anoxia on the morphology and composite metabolism of the intact aortic intima-media preparation. (1977) (34)
MORPHOLOGICAL AND BIOCHEMICAL STUDIES OF B CELLS OF FETAL RAT ENDOCRINE PANCREAS IN ORGAN CULTURE (1971) (34)
Endothelial diaphragmed fenestrae: in vitro modulation by phorbol myristate acetate (1986) (34)
Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study. (1979) (34)
Short and reversible uncoupling evokes little change in the gap junctions of pancreatic acinar cells. (1983) (34)
Dynamics of Insulin Release and Microtubular-microfilamentous System: VII. Do Microfilaments Provide the Motive Force for the Translocation and Extrusion of Beta Granules? (1974) (34)
Effects of insulin, glucagon, and epinephrine on the plasma membrane of the white adipose cell: a freeze-fracture study. (1976) (33)
Transport of horseradish peroxidase from the cell surface to the Golgi in insulin‐secreting cells: preferential labelling of cisternae located in an intermediate position in the stack. (1986) (33)
Transformation of Glicentin-containing L-Cells into Glucagon-containing Cells by Enzymatic Digestion (1980) (33)
Secretory processes, carbohydrate and lipid metabolism in isolated mouse hepatocytes. Aspects of regulation by glucagon and insulin. (1976) (32)
The fate of [125I]iodoepidermal growth factor in isolated hepatocytes: a quantitative electron microscopic autoradiographic study. (1981) (32)
PARATHYROID SECRETORY PROTEIN: IMMUNOCYTOCHEMICAL LOCALISATION WITHIN CELLS THAT CONTAIN PARATHYROID HORMONE (1978) (32)
Patterns of filipin-sterol complex distribution in intact erythrocytes and intramembrane particle-aggregated ghost membranes. (1982) (32)
Acid Phosphatase Activity in Secretory Granules of Pancreatic Beta Cells of Normal Rats (1971) (32)
Microvascular alterations in chronically streptozotocin-diabetic rats. (1973) (31)
Structural heterogeneity of endocytic membranes in macrophages as revealed by the cholesterol probe, filipin. (1981) (31)
Freeze-Etch Histology (1975) (31)
Resistance of the insulin crystal to lysosomal proteases: implications for pancreatic B-cell crinophagy (1987) (31)
LLC-PK1 cells: cloning of phenotypically stable subpopulations. (1986) (31)
Topology of morphologically detectable protein and cholesterol in membranes of polypeptide-secreting cells. (1981) (31)
Direct Demonstration of Insulin Receptor Internalization: A Quantitative Electron Microscopic Study of Covalently Bound 125I-photoreactive Insulin Incubated with Isolated Hepatocytes (1982) (30)
Morphology of Membrane Systems in Pancreatic Islets (1977) (30)
Appearance of Helix pomatia lectin-binding sites on podocyte plasma membrane during glomerular differentiation. A quantitative analysis using the lectin-gold technique. (1984) (30)
The Beta Cell and Its Responses: Summarizing Remarks and Some Contributions from Geneva (1972) (30)
Evidence for the presence of A-cells in the endocrine fetal pancreas of the rat. (1969) (29)
Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits (2010) (29)
Freeze-fracture differences between plasma membranes of descending and ascending branches of the rat Henle's thin loop. (1975) (29)
Freeze-etch histology: A comparison between thin sections and freeze-etch replicas (1975) (29)
Modulation of angiogenesis in vitro. (1992) (29)
Effects of cysteamine and antibody to somatostatin on islet cell function in vitro. Evidence that intracellular somatostatin deficiency augments insulin and glucagon secretion. (1985) (29)
Subcellular distribution of the external and internal domains of the EGF receptor in A-431 cells. (1986) (29)
Dynamic transport of SNARE proteins in the Golgi apparatus. (2005) (29)
Combined Leptin Actions on Adipose Tissue and Hypothalamus Are Required to Deplete Adipocyte Fat in Lean Rats (2006) (29)
On the "tightness" of the rabbit descending limb of the loop of Henle--physiological and morphological evidence. (1980) (29)
Opposite polarity of filipin-induced deformations in the membrane of condensing vacuoles and zymogen granules. (1980) (28)
The role of the cytoskeleton in pancreatic B-cell function. (1979) (28)
Ultrastructural immunocytochemical localization of carbonic anhydrase (1982) (28)
A Morphological Basis for Intercellular Communication between a- and d-Cells in the Endocrine Pancreas (28)
The interaction of 125I-insulin with cultured 3T3-L1 adipocytes: quantitative analysis by the hypothetical grain method. (1983) (28)
Plasminogen activator inhibitor-1 is induced in microvascular endothelial cells by a chondrocyte-derived transforming growth factor-beta. (1991) (28)
Immunochemical characterization and distribution of calcitonin in the lizard. (1981) (28)
A peculiar substructure in the postsynaptic membrane of Torpedo electroplax. (1974) (27)
The pancreatic polypeptide-rich lobe of the human pancreas: Definitive identification of its derivation from the ventral pancreatic primordium (1982) (27)
Anatomic and hormonal markers for the ventral primordium in the human pancreas? (1979) (27)
Specialization of the macrophage plasma membrane at sites of interaction with opsonized erythrocytes (1983) (27)
Glucagon : physiology, pathophysiology, and morphology of the pancreatic A-cells (1981) (26)
Carbonic anhydrase is associated with taste buds in rat tongue (1984) (26)
Extent and modulation of junctional communication between pancreatic acinar cells in vivo. (1991) (26)
Intracellular pathway followed by the insulin receptor covalently coupled to 125I-photoreactive insulin during internalization and recycling (1986) (26)
Mammalian Erv46 localizes to the endoplasmic reticulum–Golgi intermediate compartment and to cis-Golgi cisternae (2003) (25)
Studies on the mechanism of insulin release. (1975) (25)
In vitro modulation of endothelial fenestrae: opposing effects of retinoic acid and transforming growth factor beta. (1988) (25)
Glycogenosomes in renal tubular cells of diabetic animals. (1971) (25)
The Sir Henry Dale Lecture for 1983 (1984) (24)
Down-regulation of insulin receptors is related to insulin internalization. (1989) (24)
Junctional complexes and cell polarity in the urinary tubule. (1988) (24)
High somatostatin uptake by the isolated perfused dog pancreas consistent with "insulo-acinar" axis. (1982) (24)
Insulin receptor internalization and recycling: mechanism and significance. (1985) (24)
Alterations in somatostatin and other islet cell functions in the spontaneously diabetic BB Wistar rat: biochemical and morphological characterization. (1983) (23)
Polar redistribution of 125I-labelled insulin on the plasma membrane of cultured human lymphocytes (1980) (23)
Somatostatin Analog‐Induced Remission of Necrolytic Migratory Erythema Without Changes in Plasma Glucagon Concentration (1986) (23)
Kinetics of immunoreactive insulin release in obese hyperglycemic laboratory rodents. (1973) (23)
Less-understood aspects of the morphology of insulin secretion and binding. (1978) (23)
Processing of prosomatostatin. (1990) (23)
Freeze-fracture cytochemistry of neuronal membranes: inhomogeneous distribution of filipin-sterol complexes in perikarya, dendrites and axons (1982) (22)
Primitive Islets Contain Two Populations of Cells with Differing Glucagon Immunoreactivity (1981) (22)
Internalization of polypeptide hormones and receptor recycling. (1986) (22)
Distribution of intramembrane particles and filipin-sterol complexes in plasma membranes of kidney. I. Corpuscle of Malpighi. (1982) (22)
Distribution of filipin-cholesterol complexes at sites of exocytosis - a freeze-fracture study of degranulating mast cells. (1980) (21)
Detection of surface-bound ligands by freeze-fracture autoradiography (1985) (21)
Histochemical and ultrastructural identification of neurotensin cells in the dog ileum (1977) (21)
Particle aggregates in plasma and intracellular membranes of toad bladder (granular cell) (1977) (21)
Orientation of rat-liver plasma membrane vesicles. A biochemical and ultrastructural study. (1982) (21)
Angiogenesis InVitro: Morphogenetic and Invasive Properties of Endothelial Cells (1990) (20)
Polarization of gelsolin and actin binding protein in kidney epithelial cells. (1990) (20)
Freeze-fracture of membrane fusions in phagocytosing polymorphonuclear leukocytes. (1978) (20)
The lung is the major organ source of calcitonin in the lizard. (1981) (19)
Glicentin precedes glucagon in the developing human pancreas. (1982) (19)
Carbonic anhydrase is present in olfactory receptor cells (2004) (19)
An electron microscope study of the perfusion-fixed spleen (2004) (19)
Quantitative evaluation of gap junctions during development of the brown adipose tissue. (1980) (18)
[Insulin release from fetal and newborn rat pancreas in vitro: role of the adenyl cyclase system]. (1970) (18)
Two classes of microvesicles in the neurohypophysis (1977) (18)
Organ culture of fetal-rat pancreas. 3. Ultrastructural changes occurring in B cells during stimulation of insulin release. (1970) (18)
Heterogeneity of Gut Glucagon-Like Immunoreactivity (GLI) (1977) (18)
Glicentin: a precursor of glucagon? (1979) (18)
[The autonomous nervous system and the B-cell: metabolic and morphological observations made in spiny mice (Acomys cahirinus) and in cultured fetal rat pancreas]. (1970) (18)
Localisation by immunofluorescence of thyrotropin-releasing hormone in the cutaneous glands of the frog, Rana ridibunda. (1979) (18)
Polarized plasma membrane domains in cultured endothelial cells. (1985) (18)
Colchicine Administration to Mice: A Metabolic and Ultrastructural Study (1975) (18)
Somatostatin inhibition of rat growth hormone release in vitro in the presence of BaCl2 or 3‐isobutyl‐1‐methylxanthine (1974) (18)
Morphologic and Functional Changes in Sympathetic Nerve Relationships With Pancreatic α-Cells After Destruction of β-Cells in Rats (1987) (17)
Phorbol ester induces diaphragmed fenestrae in large vessel endothelium in vitro. (1987) (17)
An electron microscope study of the perfusion-fixed spleen (2004) (17)
Ultrastructural localization of glycocalyx domains in human kidney podocytes using the lectin-gold technique. (1985) (17)
Insulin immunoreactive sites demonstrated in the Golgi apparatus of pancreatic B cells. (1981) (17)
Organ culture of fetal rat pancreas. IV. Effects of metabolic inhibitors on insulin release. (1971) (17)
Receptor mediated endocytosis of polypeptide hormones: mechanism and significance. (1984) (17)
Co-culture of nerve cells and pancreatic islets. (1981) (17)
Symposium III: Hormones and hormone receptors. A morphological approach to surface receptors in islet and liver cells. (1975) (17)
Exocytosis-endocytosis as seen with morphological probes of membrane organization. (1981) (17)
Binding, membrane redistribution, internalization and lysosomal association of [125I]anti-insulin receptor antibody in IM-9-cultured human lymphocyte. A comparison with [125I]insulin. (1981) (17)
Metabolic state, pancreatic insulin content and B-cell morphology of normoglycemic spiny mice (acomys cahirinus): Indications for an impairment of insulin secretion (1970) (16)
Interleaflet clear space is reduced in the membrane of COP I and COP II-coated buds/vesicles. (1996) (16)
Ultrastructural changes in A-cells exposed to diabetic hyperglycaemia. Observations made on pancreas of chinese hamsters (1970) (16)
Glucagon in Diabetes Mellitus (1983) (15)
Hepatic autography in uncontrolled experimental diabetes and its relationships to insulin and glucagon. (1974) (15)
Pore-like structures in biological membranes. (1977) (15)
Proteolytic balance and capillary morphogenesis in vitro. (1992) (15)
Tight junctions in fetal rat liver explants grown in vitro. (1978) (15)
Patterns of cellular and subcellular organization in the endocrine pancreas. The Sir Henry Dale lecture for 1983. (1984) (15)
A Simple Method for Quick-Freezing. (1986) (14)
Endocrine-metabolic anomalies in rodents with hyperglycemic syndromes of hereditary and-or environmental origin. (1972) (14)
Prosomatostatin-derived antrin is present in gastric D cells and in portal blood. (1989) (14)
Immunocytochemical characterization of secretory granule maturation in pancreatic A-cells. (1984) (14)
Effect of a verapamil derivative (D 600) on calcium uptake and insulin release by isolated islets (1973) (14)
Receptor-mediated endocytosis of polypeptide hormones is a regulated process: inhibition of [125I]iodoinsulin internalization in hypoinsulinemic diabetes of rat and man. (1986) (14)
Beckwith-Wiedemann syndrome: a quantitative, immunohistochemical study of pancreatic islet cell populations (1985) (14)
A pancreatic polypeptide (PP)-like immunoreactant is present in the glicentin-containing cell of the cat intestine (2004) (14)
The role of the microtubular-microfilamentous system in insulin and glucagon release by the endocrine pancreas (1975) (14)
The endosomal compartment of rat hepatocytes. Its characterization in the course of [125I]insulin internalization. (1985) (14)
Microscopy: an art? (2002) (14)
Distribution of filipin-sterol complexes in plasma membranes of the kidney. II. The thin limbs of Henle's loop. (1983) (14)
Some aspects of the morphology of insulin-secreting cells. (1976) (13)
Lack of intramembranous particle clusters in collecting ducts of mice with nephrogenic diabetes insipidus. (1985) (13)
Regional heterogeneity of glycoconjugate distribution in the glomerulus revealed by lectin-gold cytochemistry and SDS-PAGE. (1986) (13)
The effect of anoxia on the ultrastructure of the superior cervical ganglion of the ratin Vitro (1971) (13)
[Phase contrast optical and ultrastuctural studies of the forms of degeneration of skeletal muscle fibers in laboratory ainimals and man]. (1967) (13)
Stretch induces granule exocytosis in toad urinary bladder. (1981) (13)
Endocrine cells in oxyntic mucosa of a dog 5 years after pancreatectomy. (1977) (13)
Glucagon- and Glicentin-Producing Cells (1983) (13)
Studies of the Effects of an Elevated Glucose Concentration on the Ultrastructure and Composite Metabolism of the Intact Rabbit Aortic Intima-Media Preparation (1979) (13)
Effect of pH and lysosomotropic agents on membrane-associated and internalized 125I-iodinated human growth hormone in cultured human lymphocytes: a quantitative biochemical and electron microscopic study. (1982) (13)
Stimulation of Insulin Release in Vitro by Non-metabolized Amino Acid Analogues 1 (1971) (13)
Chromogranin A alters ductal morphogenesis and increases deposition of basement membrane components by mammary epithelial cells in vitro. (1999) (12)
Interactions of lectins with specific cell types in toad urinary bladder. Surface distribution revealed by colloidal gold probes and label fracture. (1986) (12)
Human circulating monocytes internalize 125I-insulin in a similar fashion to rat hepatocytes: relevance to receptor regulation in target and nontarget tissues. (1985) (12)
Patterns of membrane organization in toad bladder epithelium: A freeze-fracture study (1975) (12)
Chlorpromazine in malignant insulinoma. (1972) (12)
Coat proteins and selective protein packaging into transport vesicles. (1995) (12)
Receptor-linked degradation of 125I-insulin is mediated by internalization in isolated rat hepatocytes. (1982) (12)
CONTROL OF ENDOCRINE FUNCTION IN ORGAN CULTURES OF FETAL RAT PANCREAS (1970) (12)
Modifications in the Release of Rat Growth Hormone in vitro and the Morphology of Rat Anterior Pituitaries Incubated in Various Ionophores (1976) (12)
An apparent abnormality of the B-cell microtubular system in spiny mice (Acomys cahirinus) (2004) (11)
EVIDENCE FOR GRANULOLYSIS IN THE RETINULA CELLS OF A STOMATOPOD CRUSTACEAN, SQUILLA MANTIS (1971) (11)
Horseradish peroxidase uptake and crinophagy in insulin-secreting cells. (1986) (11)
The alpha cell response to glucose change during perfusion of anti-insulin serum in pancreas isolated from normal rats (1985) (11)
Angiogenesis in Vitro: Cytokine Interactions and Balanced Extracellular Proteolysis (1994) (11)
Differential filipin labeling of the luminal membranes lining the pancreatic acinus. (1983) (11)
The kidney of spiny mice (Acomys cahirinus): Electron microscopy of glomerular changes associated with ageing and tubular glycogen accumulation during hyperglycemia (1970) (11)
Immunohistochemically Detectable Vitamin D-Dependent Calcium-Binding Protein Is Reduced in Cerebellum of Diabetic Subjects (1984) (10)
The role of microtubules and microfilaments in secretion (1976) (10)
VITAMIN-D-DEPENDENT CALCIUM BINDING PROTEIN CONTENT IS REDUCED IN KIDNEYS OF JUVENILE-ONSET DIABETICS (1982) (10)
PRESENT STATE OF THE EVIDENCE FOR MIXED ENDOCRINE AND EXOCRINE PANCREATIC CELLS IN SPINY MICE (1970) (10)
Intracellular diaphragmed fenestrae in cultured capillary endothelial cells. (1988) (10)
Direct cell-to-cell transmission of vesicular stomatitis virus. (1986) (10)
Perturbation of podocyte plasma membrane domains in experimental nephrosis. A lectin-binding and freeze-fracture study. (1984) (9)
INTRACELLULAR “α-GRANULOLYSIS” IN α-CELLS OF DIABETIC ANIMALS (1970) (9)
Morphologic probes of polypeptide hormone receptor interactions. (1980) (9)
Sequential events in the process of glucose-induced insulin release (1977) (9)
Lysosomal Association of Internalized (1979) (9)
Compensatory capabilities of islets of BB/Wor rats exposed to sustained hyperglycemia. (1990) (9)
Internalization and recycling of 125I-photoreactive insulin-receptor complexes in hepatocytes in primary culture (1986) (9)
Morphologic and functional changes in sympathetic nerve relationships with pancreatic alpha-cells after destruction of beta-cells in rats. (1987) (9)
Somatostatin-14-like antigenic sites in fixed islet D-cells are unaltered by cysteamine: a quantitative electron microscopic immunocytochemical evaluation. (1987) (9)
Gap junctions and B-cell function. (1980) (9)
12 – Biogenesis of Secretory Vesicles (1988) (9)
Virus-induced diabetes in mice: A quantitative evaluation of islet cell population by immunofluorescence technique (1978) (8)
Some factors controlling differentiation and-or modulation of rat pancreatic islet cells. (1970) (8)
A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice (1994) (8)
STIM 1 L traps and gates Orai 1 channels without remodeling the cortical (2015) (8)
Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells. (1984) (8)
Perturbation of the adipose cell plasma membrane in obese (ob/ob) mice. (1977) (8)
The morphology of proinsulin processing. (1986) (7)
Surface interactions and intracellular localization of cationic ferritin: similarity to 125I-insulin in 3T3-L1 adipocytes. (1983) (7)
REMARKS ON PANCREATIC β-CELLS IN SPONTANEOUS AND EXPERIMENTAL DIABETES IN SMALL LABORATORY RODENTS (1970) (7)
An ultrastructural study of the islet cell tumor of the golden hamster. (1971) (7)
125I-anti-insulin receptor Fab is internalized by cultured human lymphocytes. (1983) (7)
Hydrolases content in peri-insular and tele-insular exocrine pancreas (1976) (7)
[Biosynthesis and release of insulin in organ cultures of fetal rat pancreas]. (1969) (7)
Two Steps of Insulin Receptor Internalization Depend on Different Domains of the/3-Subunit (2002) (7)
Pancreatic fat. (1979) (7)
[Pancreatic polypeptide islets and glucagon islets : distinct topographic distribution in rat pancreas]. (1976) (7)
Chapter 5 Biosynthesis of Pre-proparathyroid Hormone (1981) (6)
The Morphology of Proinsulin Processing a (1986) (6)
Evidence for topographic partition of secretory function in the exocrine pancreas (1975) (6)
Relationship of binding to internalization of125I-insulin in isolated rat hepatocytes (1979) (6)
Cell motility and insulin release in monolayer cultures of endocrine pancreas (1974) (6)
The ultrastructural aspect of A-cells of non-ketotic and ketotic diabetic animals: indications for stimulation and inhibition of glucagon production. (1970) (6)
The ciliary junction: a unique membrane specialization in the ciliate, Glaucoma ferox. (1981) (6)
Clarification of the osmiophilic granules of the rat pinealocytes byp-chlorophenylalanin (1968) (6)
Islet cell population in ob/ob and db/db mice. Abstr. (1976) (6)
An alteration in internodal myelin membrane structure in large sciatic nerve fibres in rats with acute streptozotocin diabetes and impaired nerve conduction velocity (1978) (5)
Role of microtubules in hormone biosynthesis (1977) (5)
Role of glucagon in diabetes. (1977) (5)
Feasibility of freeze-fracturing single isolated renal tubules. (1977) (5)
Protein A-gold complex for postembedding staining of intracellular antigens. (1980) (5)
Enzyme‐Induced Modifications of Beta Cell Function (1974) (5)
Membrane cycling in secretion: a morphological approach. (1981) (5)
Internalization of polypeptide hormones and receptor recycling (2005) (5)
The effect of hyperoxia on the ultrastructure of the superior cervical ganglion of the ratin vitro (1971) (5)
Filipin labelling of lipid droplets in lactating rat mammary gland. (1983) (4)
Ultrastructural detection of granulated cells in the autonomic ganglia of the rat pancreas (1985) (4)
PROPERTIES OF ISOLATED β-GRANULES IN SUSPENSION* (1970) (4)
Loss of polarization of plasma membrane domains in transformed pancreatic endocrine cell lines. (1986) (4)
Tris(hydroxymethyl)aminomethane Inhibits the Synthesis and Processing of Proinsulin in Isolated Rat Pancreatic Islets Without Affecting Release of Insulin Stores (1986) (4)
Hepatocyte Growth Factor Increases Urokinase-type Plasminogen Activator ( uPA ) and uPA Receptor Expression in Madin-Darby Canine Kidney Epithelial Cells (2001) (4)
Receptor binding and internalization of biosynthetic human insulin in isolated rat hepatocytes (1982) (4)
A role for GTP-binding proteins in vesicular transport through the Golgi complex. (1989) (4)
Morphometric and functional studies of islets in diabetes-prone BB/W rats that are discordant for overt diabetes (1989) (4)
Subcellular organelles involved in the conversion of biosynthetic precursors of parathyroid hormone. (1977) (4)
Glucagon degradation in isolated rat hepatocytes: Effect of ammonium chloride and chloroquine (1981) (4)
125I-Insulin is preferentially internalized in regions of the hepatocytes rich in lysosomal and Golgi structures (1979) (3)
Enzyme‐Induced Modifications of Beta Cell Function (1974) (3)
Dual effect of colchicine upon the dynamics of insulin release by the isolated perfused rat pancreas (1973) (3)
[Lamellar cytoplasmic inclusions in the collecting tubules of the kidney in the course of osmotic nephrosis. Electron microscopical study]. (1967) (3)
Morphological characterization of membrane systems in A- and B-cells of the Chinese hamster (1974) (3)
Insulin action at the cellular level: anatomical considerations. (1985) (3)
Erratum: Underexpression of β cell high K(m) glucose transporters in noninsulin-dependent diabetes (Science (26 Oct. 1990) (546)) (1990) (3)
‘Obligatory’ association between A and D cells demonstrated by bipolar islets in neonatal pancreas (1981) (3)
Morphological studies of a new transplantable salivary gland tumor in C3H mice (1969) (3)
Biochemical and electronmicroscopic studies on perfused livers from normal and obob mice. Abstr. (1971) (3)
Cytochalasin-induced potentiation of insulin release : dependency on calcium and hormonal compartmentation in the ß-cell (1973) (3)
Release of growth hormone from ox pituitary slices after pronase treatment (1975) (2)
Rapid in vitro formation of smooth endoplasmic reticulum aggregates within peptide‐producing islet cells (1987) (2)
The microtubular-microfilamentous system of the pancreatic B-cell (1973) (2)
Liver perfusion of normal and obob mice, preliminary results. Abstr. (1972) (2)
The SEC23-SEC31 interface plays critical role for export of procollagen from the endoplasmic reticulum. (2012) (2)
[Heterocellular coupling in cultures of endocrine pancreatic cells]. (1981) (2)
Intracellular localization of 125 I-labeled insulin in hepatocytes from intact rat liver ( insulin receptor / autoradiography / ultrastructure ) (2)
Hereditary Hyperglycemic Syndromes in Laboratory Rodents (1976) (2)
[Spontaneous diabetes in animals. Considerations of the pathogenesis of acute syndrome and on the morphology of lesions of chronic syndrome]. (1970) (2)
[Preparation for electron microscopy of adipose tissue cells, isolated as well as in situ]. (1968) (1)
Motion analysis in pancreatic endocrine cells: saltatory movements of secretory granules along oriented pathways (1976) (1)
Kinetics of immunoreactive insulin in obese hyperglycemic laboratory rodents. (1973) (1)
Inhomogeneity of surface labelling of B-cells at prospective sites of exocytosis (1979) (1)
[Immunocytochemical anatomy of alpha granules in the human endocrine pancreas]. (1979) (1)
Biochemical and morphological events associated with the development of fetal rat pancreas "in vivo" and "in vitro": effect of glucagon and of other agents. (1970) (1)
Seventh Annual Meeting of the European Association for the Study Of Diabetes Southampton, England, September 15–17, 1971 Abstacts, Part 1 (1971) (1)
Change in islet cell populations of ob/ob and db/db mice. Abstr. (1976) (1)
Membrane topology as revealed by the binding of macromolecules. (1976) (1)
Albert E. Renold: July 10, 1923–March 21, 1988 (1988) (1)
Relationship of binding to internatlization of 125I-insulin in isolated rat hepatocytes. (1979) (1)
Effect of deuterium oxide and cytochalasin B on the dynamics of insulin release by the isolated perfused rat pancreas (1973) (1)
The effect of cytochalasin B on the B-cell biphasic response and apparent sensitivity to glucose in the isolated perfused rat pancreas (1973) (1)
[Membrane binding of insulin antigenic sites in the Golgi apparatus of pancreatic B cells]. (1983) (1)
Humans: New Insights from Magnetic Resonance Spectroscopy Unraveling the Cellular Mechanism of Insulin Resistance in (2015) (1)
[Interaction of epidermal growth factor with human fibroblasts in culture: an autoradiographic study at the ultrastructural level]. (1978) (1)
Participation of the microfilamentous cell web in the initial secretory response of the beta cell (1973) (1)
Microtubular-microfilamentous system, motile events and insulin release in the pancreatic B-cell (1978) (0)
[Ultrastructure of endocrine cells in the gastrointestinal epithelium]. (1969) (0)
Differentiations of the Cell Surface in Freeze-Etching (1975) (0)
[Morphological and functional studies of the rat superior cervical ganglion during hyperoxia]. (1970) (0)
Eighth annual meeting of the European Association for the Study of Diabetes (1973) (0)
[Ultrastructural changes in the organization of plasma membranes in adipocytes of obese mice (ob/ob)]. (1976) (0)
[PHASE-CONTRAST MICROSCOPY OF ULTRA-THIN TISSUE SECTIONS AND ITS USES IN BIOLOGY]. (1964) (0)
GAP J UNCTIONS I N M ESANGIAL A ND L ACIS C ELLS (1974) (0)
ARY tocyte growth factor stimulates e-like structures by cloned (0)
Transports of delight (1996) (0)
[Ultrastructural detection of the heterogeneity of glycocalyx in convoluted and straight proximal tubules of rat kidney by the lectin-gold complex technic]. (1983) (0)
[On some structural and ultrastructural aspects of the human hepatic cell in diabetes]. (1966) (0)
What a Book on Cell Ultrastructure Should Not Be (1989) (0)
[Physiology of insulin secretion. 2. Further interpretations]. (1972) (0)
Transports of delight (1996) (0)
[Activity of somatostatin-containing cells of the Ilets of Langerhans in experimental diabetes]. (1975) (0)
Co-localization of t 2 l-Epidermal Growth Factor and Ferritin-low Density Lipoprotein in Coated Pits : A Quantitative Electron Microscopic Study in Normal Mutant Human Fibroblasts and (2003) (0)
125 I-insulin binding to cultured human lymphocytes . Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography (2018) (0)
[Morphological aspects of the interaction of insulin with its target cell]. (1980) (0)
Correction (1994) (0)
[Evidence for existence of pores in intramembranous particles revealed by freeze fracturing]. (1976) (0)
[Organoculture of rat fetal pancreas: morphologic study and insulin liberation in vitro]. (1969) (0)
In vivo insulin secretion dynamics in rodents with spontaneous or acquired obesity or diabetes. Abstr. (1971) (0)
Microtubules and the biosynthesis, conversion and release of (pro)insulin (1976) (0)
Cargo selection and vesicle budding (1997) (0)
Vesículas y transporte intracelular (1996) (0)
A new look at the metabolism of the arterial wall. (1976) (0)
[Asymmetrical distribution of clathrin in the Golgi apparatus of polypeptide-secreting cells]. (1984) (0)
Guest Lecture: Intracellular events underlying secretion of insulin by the beta cell (1978) (0)
Symposium: obese-hyperglycaemic mice (1972) (0)
Membrane recycling in the pancreatic beta cell (1972) (0)
Proinsulin in the Same Secretory Vesicle (2002) (0)
EXOCYTOSIS-ENDOCYTOSIS IN MORPHOLOGICAL PERSPECTIVE (1981) (0)
Proinsulin Conversion Site (1988) (0)
Morphologic Study of Glucagon Release (1977) (0)
Interpretation of Freeze-Etch Replicas (1975) (0)
Proteolytic balance and capillary morphogenesis in vitro (1991) (0)
[Morphological and physiological lesions in the complex syndrome of spiny mice (Acomys cahirinus)]. (1968) (0)
[Ultrastructural visualization of binding and internalization of cholera and tetanuts toxins]. (1981) (0)
(Pro)insulin associates withGolgi membranes ofpancreatic B cells (Golgi complex/conversion/sorting out/secretory po!ypeptides/immunocytochemistry) (1984) (0)
Microfilamentous-microtubular system, motile events and insulin release in the pancreatic B-cell (1978) (0)
Insulin Interaction with Target Cells Morpho-Functional Aspects (1986) (0)
The Interaction of '251-Insulin with Cultured 3T3-L1 Adipocytes: (1983) (0)
Great Britain PORE-LIKE STRUCTURES IN BIOLOGICAL MEMBRANES (2005) (0)
Electron Microscopy to Examine the Effect of the Anti-GOS-28 Antibody on Vesicular Transport (2002) (0)
[Histomorphological and phase contrast findings in tissue ultrasections in pancreatic lesions following a perforating gastric ulcer]. (1965) (0)
THE MORPHOLOGY OF INTRACELLULAR PROTEIN TRANSPORT (1995) (0)
during Uncoupling of Rat Insulin-producing Cells (1990) (0)
Seventh Annual Meeting of the European Association for the Study of Diabetes (1972) (0)
[Reticulo-endothelial cells of the liver and Disse's space]. (1967) (0)
Adequate Connexin-mediated Is Required for Proper Insulin Production (1995) (0)
Proceedings: The freeze-etching approach to the study of islet pathophysiology in diabetes. (1974) (0)
[Phase-contrast microscopic studies of so-called "osmotic nephrosis caused by saccharose" in the mouse]. (1967) (0)
[Changes induced by local and neurolytic analgesic agents on the peripheral nerves. Electron microscope observations]. (1962) (0)
THE TOPOGRAPHY OF ELECTRICAL SYNCHRONY AMONG f-CELLSINTHE MOUSE ISLETOF (2011) (0)
[Three-dimensional reconstruction of capillary pericytes in muscles]. (1969) (0)
Colchicine Administration to Mice: A Metabolic and Ultrastructural Study (1975) (0)
[Experimental studies on the ultrastructure of rat epiphysis]. (1969) (0)
Effect of colchicine and vincristine upon insulin secretion by the isolated perfused rat pancreas (1972) (0)
THE REGULATION OF METABOLISM (1978) (0)
Participation of microtubules and microfilaments in the dynamics of insulin secretion by the isolated perfused rat pancreas (1972) (0)
Modulation of an early and lethal autoimmune diabetes in transgenic mice by IL-4 overexpression and treatment with anti-IFN-γ antibody (1999) (0)
Control of fuel fluxes by polypeptides. (1980) (0)
Binding , Internalization , and Lysosomal Association of 125 I-Glucagon in Isolated Rat Hepatocytes (2013) (0)
Clinical Medicine Esterase and Acid Phosphatase in the Identification of Cell Type in Leukaemia (0)
招待講演1 The morphology of interactions underlying insulin secretion (1984) (0)
Microstructure and function of cells. Electron micrographs of cell ultrastructure. Ellis horwood series in life sciences By Andreas Bubel. New York: John Wiley & Sons, Inc. (1989). 271 pp. $69.95 (1989) (0)
Motile events in islet cells: role of microtubules and microfilaments (1976) (0)
[Immunocytochemical identification of the glucagon-secreting cells in gastric mucosa]. (1976) (0)
TT Proinsulin in the Same Secretory Vesicle (1994) (0)

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