Lowell Paul Hager
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Chemistry Biology
Lowell Paul Hager's Degrees
- PhD Biochemistry University of California, Davis
- Bachelors Chemistry University of California, Davis
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(Suggest an Edit or Addition)Lowell Paul Hager's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Chloroperoxidase. I. Isolation and properties of the crystalline glycoprotein. (1966) (454)
- Chloroperoxidase. II. Utilization of halogen anions. (1966) (392)
- Methyl chloride transferase: a carbocation route for biosynthesis of halometabolites. (1990) (238)
- Mössbauer and electron paramagnetic resonance studies of horseradish peroxidase and its catalytic intermediates. (1984) (178)
- Chloroperoxidase compound I: Electron paramagnetic resonance and Mössbauer studies. (1984) (174)
- Chloroperoxidase. VII. Classical peroxidatic, catalatic, and halogenating forms of the enzyme. (1970) (165)
- Horseradish peroxidase compound I: evidence for spin coupling between the heme iron and a ‘free’ radical (1979) (162)
- Highly enantioselective epoxidation of disubstituted alkenes with hydrogen peroxide catalyzed by chloroperoxidase (1993) (155)
- Halohydrocarbon Synthesis by Bromoperoxidase (1978) (142)
- Chloroperoxidase halogenation reactions. Chemical versus enzymic halogenating intermediates. (1982) (132)
- Highly Enantioselective Epoxidation of 1,1-Disubstituted Alkenes Catalyzed by Chloroperoxidase (1995) (111)
- Spectrum of chloroperoxidase compound I. (1980) (105)
- Electron-nuclear double resonance of horseradish peroxidase compound I. Detection of the porphyrin pi-cation radical. (1981) (104)
- Probing the heme iron coordination structure of pressure-induced cytochrome P420cam. (1996) (101)
- A poly(dT)-stimulated ATPase activity associated with simian virus 40 large T antigen. (1979) (101)
- Chloroperoxidase. 8. Formation of peroxide and halide complexes and their relation to the mechanism of the halogenation reaction. (1970) (100)
- Studies of the ferric forms of cytochrome P-450 and chloroperoxidase by extended x-ray absotption fine structure. Characterization of the iron-nitrogen and iron-sulfur distances (1978) (98)
- Chloroperoxidase, a janus enzyme. (2008) (95)
- CRYSTALLINE CYTOCHROME B1 FROM ESCHERICHIA COLI. (1964) (94)
- The P-450 nature of the carbon monoxide complex of ferrous chloroperoxidase. (1973) (90)
- Chloroperoxidase. IX. The structure of compound I. (1972) (90)
- Ligand and halide binding properties of chloroperoxidase: peroxidase-type active site heme environment with cytochrome P-450 type endogenous axial ligand and spectroscopic properties. (1986) (88)
- Chloroperoxidase as Enantioselective Epoxidation Catalyst: An Efficient Synthesis of (R)-(-)-Mevalonolactone. (1996) (87)
- Biological Chlorination VI. CHLOROPEROXIDASE: A COMPONENT OF THE β-KETOADIPATE CHLORINASE SYSTEM (1961) (84)
- BROMOPEROXIDASES AND HALOGENATED LIPIDS IN MARINE ALGAE 1 (1980) (81)
- Crystalline pyruvate oxidase from Escherichia coli. II. Activation by phospholipids. (1971) (79)
- C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols. (2006) (78)
- Studies on Cytochrome b562 of Escherichia coli I. PURIFICATION AND CRYSTALLIZATION OF CYTOCHROME b562 (1966) (77)
- Oxygen-17 ENDOR of horseradish peroxidase compound I (1981) (76)
- Highly Enantioselective Propargylic Hydroxylations Catalyzed by Chloroperoxidase (1999) (74)
- On the mechanism of inhibition of enzymatic halogenation by antithyroid agents. (1962) (72)
- Chemical nature of the porphyrin pi cation radical in horseradish peroxidase compound I. (1983) (71)
- Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue. (1999) (70)
- 6 – Peroxidases, Catalases, and Chloroperoxidase (1979) (70)
- Crystalline pyruvate oxidase from Escherichia coli. 3. Phospholipid as an allosteric effector for the enzyme. (1971) (67)
- Utilization of peroxide and its relevance in oxygen insertion reactions catalyzed by chloroperoxidase. (2001) (65)
- Mössbauer investigations of chloroperoxidase and its halide complexes. (1973) (65)
- Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical. (2006) (64)
- Purification and properties of bromoperoxidase from Penicillus capitatus. (1981) (63)
- Enantioselective Epoxidation of ω-Bromo-2-methyl-1-alkenes Catalyzed by Chloroperoxidase. Effect of Chain Length on Selectivity and Efficiency (1997) (63)
- Crystalline flavin pyruvate oxidase from Escherichia coli. I. Isolation and properties of the flavoprotein. (1966) (63)
- Chiral synthons via chloroperoxidase catalysis (1998) (63)
- Synthesis of brominated heptanones and bromoform by a bromoperoxidase of marine origin. (1981) (62)
- The reaction of chlorite with horseradish peroxidase and chloroperoxidase. Enzymatic chlorination and spectral intermediates. (1974) (61)
- LIPOIC ACID DEHYDROGENASE: THE FUNCTION OF E. COLI FRACTION B* (1953) (60)
- Chloroperoxidase. IV. Evidence for an ionic electrophilic substitution mechanism. (1967) (59)
- The detection of two electron paramagnetic resonance radical signals associated with chloroperoxidase compound I. (1982) (56)
- Oxidation of horseradish peroxidase compound II to compound I. (1979) (56)
- [55] Purification of chloroperoxidase from Caldariomyces fumago (1978) (55)
- An electron paramagnetic resonance study of the high and low spin forms of chloroperoxidase. (1980) (54)
- Activation of pyruvate oxidase by monomeric and micellar amphiphiles. (1978) (54)
- Expression of Batis maritima methyl chloride transferase in Escherichia coli. (1999) (52)
- Directed Evolution of Chloroperoxidase for Improved Epoxidation and Chlorination Catalysis (2001) (52)
- Mechanism of the chlorination reaction catalyzed by horseradish peroxidase with chlorite. (1979) (51)
- AN ENZYMATIC CHLORINATION REACTION (1959) (51)
- Letter: Chloroperoxidase. Evidence for P-450 type heme environment from magnetic circular dichroism spectroscopy. (1976) (50)
- Mössbauer investigations of high-spin ferrous heme proteins. II. Chloroperoxidase, horseradish peroxidase, and hemoglobin. (1975) (50)
- Examining the Role of Glutamic Acid 183 in Chloroperoxidase Catalysis* (2003) (49)
- Resonance Raman studies of isotopically labeled chloroperoxidase. (1986) (45)
- Biological chlorination. III. beta-Ketoadipate chlorinase: a soluble enzyme system. (1959) (44)
- Transient Heme N-Alkylation of Chloroperoxidase by Terminal Alkenes and Alkynes (1995) (44)
- Identification of the fifth axial heme ligand of chloroperoxidase. (1988) (44)
- cDNA cloning of Batis maritima methyl chloride transferase and purification of the enzyme. (1998) (43)
- Kinetics of two-electron oxidations by the compound I derivative of chloroperoxidase, a model for cytochrome P450 oxidants. (2006) (43)
- Oxidation-reduction potential measurements on chloroperoxidase and its complexes. (1976) (42)
- Preparation and properties of ferrous chloroperoxidase complexes with dioxygen, nitric oxide, and an alkyl isocyanide. Spectroscopic dissimilarities between the oxygenated forms of chloroperoxidase and cytochrome P-450. (1985) (42)
- Chemical modification of chloroperoxidase with diethylpyrocarbonate. Evidence for the presence of an essential histidine residue. (1990) (41)
- Kinetic analysis of compound I formation and the catalatic activity of chloroperoxidase. (1981) (40)
- Cloning and sequencing of chloroperoxidase cDNA. (1986) (40)
- Asymmetric epoxidation of functionalized cis-olefins catalyzed by chloroperoxidase (1999) (39)
- Chloroperoxidase: P-450 type absorption in the absence of sulfhydryl groups. (1975) (39)
- Probing the heme iron coordination structure of alkaline chloroperoxidase. (1996) (39)
- Resonance Raman investigations of chloroperoxidase, horseradish peroxidase, and cytochrome c using Soret band laser excitation. (1979) (38)
- Chloroperoxidase generation of singlet Δ molecular oxygen observed directly by spectroscopy in the 1- to 1.6-μm region (1983) (38)
- BIOLOGICAL CHLORINATION. IV. PEROXIDATIVE NATURE OF ENZYMATIC CHLORINATION1 (1959) (38)
- Engineering chloroperoxidase for activity and stability (2001) (37)
- Occurrence of fatty acid chlorohydrins in jellyfish lipids. (1977) (37)
- BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (36)
- On the mechanism of alpha-oxoglutarate oxidation in Escherichia coli. (1961) (35)
- Single strand DNA binding of simian virus 40 tumor antigen. (1979) (35)
- The reaction of chloroperoxidase with chlorite and chlorine dioxide. (1981) (35)
- 1-Iodo-3,3-dibromo-2-heptanone, 1,1,3,3-tetrabromo-2-heptanone, and related compounds from the red alga Bonnemaisonia hamifera (1975) (34)
- The generation of a hyperporphyrin spectrum upon thiol binding to ferric chloroperoxidase. Further evidence of endogenous thiolate ligation to the ferric enzyme. (1984) (34)
- Epoxidation of indene by chloroperoxidase (2000) (34)
- Role for endonuclease I in the transmission process of colicin E 2 . (1972) (34)
- A resolution of the Escherichia coli pyruvate dehydrogenase complex. (1961) (33)
- Heme sulfuric anhydrides. II. Properties of heme models prepared from mesoheme sulfuric anhydrides. (1970) (33)
- X-ray Absorption Near Edge Studies of Cytochrome P-450-CAM, Chloroperoxidase, and Myoglobin (1995) (33)
- Oxygenated cytochrome P-450-CAM and chloroperoxidase: direct evidence for sulfur donor ligation trans to dioxygen and structural characterization using EXAFS spectroscopy (1986) (32)
- The chloroperoxidase-catalyzed oxidation of thiols and disulfides to sulfenyl chlorides. (1974) (31)
- Characterization of the proteolytic activation of pyruvate oxidase. Control by specific ligands and by the flavin oxidation-reduction state. (1977) (31)
- Chemistry and functions of colicins (1973) (31)
- CHEMISTRY OF PEROXIDASE INTERMEDIATES * (1975) (31)
- Post-translational modifications of chloroperoxidase from Caldariomyces fumago. (1987) (30)
- Molecular iodine as an obligate intermediate in the iodination of tyrosine by chloroperoxidase. (1969) (30)
- Chloroperoxidase-mediated asymmetric epoxidation. Synthesis of (R)-dimethyl 2-methylaziridine-1,2-dicarboxylate—a potential α-methylamino acid synthon (1997) (30)
- Highly Enantioselective Epoxidation of Disubstituted Alkenes with Hydrogen Peroxide Catalyzed by Chloroperoxidase. (1993) (30)
- The ferric-hydroperoxo complex of chloroperoxidase. (2007) (28)
- Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid. (1959) (28)
- Reactivation of the lipid-depleted pyruvate oxidase system from Escherichia coli with cell envelope neutral lipids. (1975) (28)
- Heme sulfuric anhydrides. I. Synthesis and reactions of mesoheme sulfuric anhydride. (1970) (28)
- Characterization of the oxidized states of bromoperoxidase. (1985) (27)
- High-pressure-assisted reconstitution of recombinant chloroperoxidase. (1995) (27)
- The intriguing enhancement of chloroperoxidase mediated one-electron oxidations by azide, a known active-site ligand. (2011) (26)
- Characterization of the catalytic properties of bromoperoxidase (1989) (26)
- Structure of the modified heme in allylbenzene-inactivated chloroperoxidase determined by Q-band CW and pulsed ENDOR (1997) (26)
- Isolation and nucleotide sequence of the chloroperoxidase gene from Caldariomyces fumago (1988) (26)
- Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase* 210 (2003) (25)
- Conversion of α-amino acids and peptides to nitriles and aldehydes by bromoperoxidase (1985) (25)
- Flavoprotein-catalyzed pyruvate oxidation in Lactobacillus delbrueckii. (1954) (24)
- Mössbauer and electron paramagnetic resonance studies of chloroperoxidase following mechanism-based inactivation with allylbenzene. (1996) (24)
- Oxygen-17 nuclear magnetic resonance spectroscopic studies of carbonmonoxyperoxidases. (1988) (24)
- Activation of Escherichia coli pyruvate oxidase enhances the oxidation of hydroxyethylthiamin pyrophosphate. (1991) (24)
- ENDOR determination of heme ligation in chloroperoxidase and comparison with cytochrome P-450Cam (1994) (23)
- Unusual propargylic oxidations catalyzed by chloroperoxidase. (1998) (23)
- Resonance Raman spectra of chloroperoxidase. (1976) (23)
- The amino acid sequence of cytochrome b562 of Escherichiacoli (1968) (22)
- BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (22)
- A colorimetric method for detection and quantification of chlorinating activity of hemeperoxidases. (2006) (22)
- Role of flavin in acetoin production by two bacterial pyruvate oxidases. (1993) (21)
- Role of the divalent metal cation in the pyruvate oxidase reaction. (1982) (21)
- Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron. (1991) (21)
- Isolation of directed evolution mutants of chloroperoxidase resistant to suicide inactivation by primary olefins (2000) (21)
- Method for Determination of Oxygen-18 Content of Inorganic Phosphate (1958) (21)
- A kinetic epoxidation assay for chloroperoxidase. (1999) (21)
- Zero-field splitting of Fe3+ in horseradish peroxidase and of Fe4+ in horseradish peroxidase compound I from electron spin relaxation data. (1983) (21)
- Development of semi-continuous and continuous flow bioreactors for the high level production of chloroperoxidase (1989) (20)
- Broad-line nuclear magnetic resonance studies of chloroperoxidase. (1976) (20)
- Intricenyne and related halogenated compounds from Laurencia intricata (1978) (19)
- The peroxidation of molecular iodine to iodate by chloroperoxidase. (1968) (19)
- Isolation and characterization of horseradish peroxidase compound X. (1982) (19)
- Purification of chloroperoxidase from Caldariomyces fumago. (1978) (18)
- Phosphine binding as a structural probe of the chloroperoxidase active site: spectroscopic evidence for endogenous thiolate ligation to the heme iron (1985) (18)
- Compound X. An intermediate in enzymatic halogenation. (1976) (18)
- Studies on cytochrome b562 of Escherichia coli. II. Reconstitution of cytochrome b562 from apoprotein and hemin. (1967) (18)
- Characterization of the α-peptide released upon protease activation of pyruvate oxidase (1985) (17)
- A rearranged dibromotyrosine metabolite from verongia aurea (1975) (17)
- Reconstitution of native Escherichia coli pyruvate oxidase from apoenzyme monomers and FAD. (1982) (17)
- A Lifetime of Playing with Enzymes (2010) (16)
- The Oxygen Exchange Reaction Catalyzed by the Succinic-thiokinase1 (1957) (16)
- A specific DNA unwinding activity associated with SV40 large T antigen. (1980) (16)
- Isolation and characterization of the protease-activated form of pyruvate oxidase. Evidence for a conformational change in the environment of the flavin prosthetic group. (1983) (16)
- Crystallization and properties of glutamate decarboxylase from Escherichia coli strain w+. (1967) (16)
- A kinetic study of the binding of carbon monoxide to ferrous chloroperoxidase. (1982) (15)
- Protein bromination by bromoperoxidase from Penicillus capitatus. (1984) (15)
- Iodination of zeta protein by lactoperoxidase. Chloroperoxidase and chloramine T. (1976) (15)
- Molecular parameters of 6-methylsalicylic acid synthetase from gel filtration and sucrose density gradient centrifugation. (1968) (15)
- A single-step large-scale purification of pyruvate oxidase. (1987) (14)
- Purification and characterization of culture-derived exoantigens of Plasmodium falciparum. (1985) (14)
- Fructose induces and glucose represses chloroperoxidase mRNA levels. (1986) (13)
- Escherichia coli pyruvate oxidase: interaction of a peripheral membrane protein with lipids. (1982) (12)
- [84] Iodination of tyrosine by chloroperoxidase; preparation of chloroperoxidase (Caldariomyces fumago) (1970) (12)
- Highly Enantioselective Propargylic Hydroxylations Catalyzed by Chloroperoxidase. (1999) (12)
- Isolation of a heme crevice peptide from affinity-labeled horseradish peroxidase. (1980) (12)
- Identification of the high-affinity lipid binding site in Escherichia coli pyruvate oxidase. (1986) (12)
- Characterization of Laurencia Species by Gas Chromatography-Mass Spectrometry (1979) (11)
- Mother Nature likes some halogenated compounds. (1982) (11)
- Crystallographic study of cytochrome b562 from Escherichia coli (1972) (11)
- Molecular structure of acetoxyintricatol: A new bromo compound from . (1974) (11)
- Hypersensitive radical probe studies of chloroperoxidase-catalyzed hydroxylation reactions. (1998) (11)
- [75] Phosphate-linked pyruvic acid oxidase from Lactobacillus delbrückii: (Bacillus acidificans longissimus, Lafar) Pyruvate + P + O2 → Ac∼P -t- CO2 + H2O2 (1955) (10)
- Coupling between phosphorylation and flavin adenine dinucleotide reduction with the pyruvate oxidase of L. delbrueckii enzyme. (1961) (10)
- Inhibition of Colicin E2 Activity by Bacterial Lipopolysaccharide (1970) (10)
- Synthesis of D,L-Caldariomycin1 (1961) (10)
- Systematic trends in the spectroscopic properties of low-spin ferric ligand adducts of cytochrome P-450 and chloroperoxidase : the transition from normal to hyper spectra (1992) (10)
- [67] The preparation and properties of cytochrome b562 from Escherichia coli (1967) (9)
- The active sites of chloroperoxidase and cytochrome P-450-CAM: Comparative spectroscopic and ligand binding properties (1983) (8)
- ACTIVATION OF A FERRICYANIDE LINKED PYRUVATE OXIDASE BY α-TOCOPHEROL ESTERS (1957) (8)
- [66] The preparation of bacterial cytochrome b1 (1967) (8)
- Cytochrome P-450 and peroxidase chemistry. (1994) (8)
- Solubilization and enzymic activity of bacterial cytochrome b. (1960) (7)
- Binding of pyruvate oxidase α-peptide to phospholipid vesicles (1987) (7)
- Biological Chlorination (7)
- [51] Pyruvic (cytochrome b1) dehydrogenase (crystalline) (1966) (6)
- STUDIES ON THE MECHANISM OF ACTION OF COLICIN E2 (1973) (6)
- Reconstitution of the lipid-depleted pyruvate oxidase system of Escherichia coli: the palmitic acid effect. (1984) (6)
- Chloroperoxidase generation of singlet Delta molecular oxygen observed directly by spectroscopy in the 1- to 1.6-mum region. (1983) (6)
- Reconstitution of Colicin E2-Induced Deoxyribonucleic Acid Degradation in Spheroplast Preparations (1973) (6)
- Enantioselective Epoxidation of ω‐Bromo‐2‐methyl‐1‐alkenes Catalyzed by Chloroperoxidase. Effect of Chain Length on Selectivity and Efficiency. (1997) (6)
- Minimum requirements for protease activation of flavin pyruvate oxidase. (1991) (5)
- Characterization of the alpha-peptide released upon protease activation of pyruvate oxidase. (1985) (5)
- A method for the rapid determination of trace organic halogens in lipids. (1977) (5)
- Studies on cytochrome b-562 of Escherichia coli. I. Purification and crystallization of cytochrome b-562. (1966) (5)
- Trypsin activation of a ferricyanide-linked pyruvic acid oxidation. (1957) (5)
- Enzymatic Steps in Alpha-Keto Acid Oxidation (1953) (4)
- The synthesis and assay of high specific acitivty of 14 C-trimethyloxonium tetrafluoroborate. (1971) (4)
- Modification of the Cary Model 14 recording spectrophotometer for low-temperature spectroscopy. (1965) (4)
- Chemical and transient state kinetic studies on the formation and decomposition of horseradish peroxidase compounds XI and XII. (1991) (4)
- Crystallization and preliminary X-ray data for chloroperoxidase. (1982) (4)
- Mechanism of the inhibition of enzymatic halogenation by antithyroid agents. (1966) (4)
- A crystalline flavin pyruvate oxidase. (1961) (3)
- Asymmetric Epoxidation of Functionalized cis‐Olefins Catalyzed by Chloroperoxidase. (1999) (3)
- Application of I mossbauer effect to biological systems: studies with heme models. (1970) (3)
- [120] Glutamate decarboxylase (Escherichia coli) (1970) (3)
- Activation of Pyruvate Oxidase and Interaction with Membrane Components (1982) (3)
- Conversion of alpha-amino acids and peptides to nitriles and aldehydes by bromoperoxidase. (1985) (2)
- The amino acid sequence of cytochrome b562 of Escherichia coli. (1968) (2)
- Highly Enantioselective Epoxidation of 1,1-Disubstituted Alkenes Catalyzed by Chloroperoxidase. (1995) (2)
- Binding of pyruvate oxidase alpha-peptide to phospholipid vesicles. (1987) (2)
- CHEMICAL NATURE AND REACTION OF CHLOROPEROXIDASE COMPOUND I (1972) (2)
- Crystalline Cytochrome b, from Escherichia coZi* (2003) (1)
- Purification of cytochrome b1 from Escherichia coli. (1978) (1)
- Free Radical Nature of Compound I (1982) (1)
- Isolation of the active site of cytochrome c by reverse-phase high-performance liquid chromatography (1990) (1)
- On the Mechanism of et-Oxoglutarate Oxidation in Escherichia coli (2005) (1)
- Affinity labeling of myoglobin with mesoheme sulfuric anhydride. (1970) (1)
- Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase* □ S (2003) (0)
- Phosphine Binding as a Structural Probe of the Chloroperoxidase Active Sitc: Spectroscopic Evidence for Endogenous Thiolate Ligation to the Heme Iron (1986) (0)
- Engineering chloroperoxidase for enhanced catalytic activity (2001) (0)
- Electron-Paramagnetic-Resonance of Allylbenzene-Inactivated Chloroperoxidase and a Possible Intermediate in Reactivation (1995) (0)
- Method for immobilizing antimicrobial emnen (1977) (0)
- Mesoheme sulfuric anhydride as a heme protein structure probe reaction with cytochrome b 562. (1970) (0)
- Crystallographic study of cytochrome b 562 from Escherichia coli. (1972) (0)
- Oxygenated Cytochrome P-450-CAM and Chloroperoxidase: Direct Evidence for Sulfur Donor Ligation trans to Dioxygen and Structural Characterization Using EXAFS Spectroscopy. (1987) (0)
- Mechanism-based inactivation of chloroperoxidase with terminal olefins. Identification of an intermediate in the spontaneous enzyme reactivation (1995) (0)
- Ligands in Heme Iron in Chloroperoxidase: An Electron Paramagnetic Resonance Study (1982) (0)
- MOLECULAR STRUCTURE OF ACETOXYINTRICATOL, A NEW COMPOUND FROM LAURENCIA INTRICATA (1974) (0)
- Inhibition ofColicin E2Activity byBacterial Lipopolysacchari de (1970) (0)
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