Lowell Paul Hager

Lowell Paul Hager's AcademicInfluence.com Rankings

Lowell Paul Hager

Chemistry

#3086

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#4074

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chemistry Degrees

Lowell Paul Hager

Biology

#8722

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#11847

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Molecular Biology

#1133

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#1159

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Biochemistry

#1285

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#1404

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biology Degrees

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Chemistry
Biology

Lowell Paul Hager's Degrees

PhD Biochemistry University of California, Davis
Bachelors Chemistry University of California, Davis

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Lowell Paul Hager's Published Works

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Published Works

Chloroperoxidase. I. Isolation and properties of the crystalline glycoprotein. (1966) (454)
Chloroperoxidase. II. Utilization of halogen anions. (1966) (392)
Methyl chloride transferase: a carbocation route for biosynthesis of halometabolites. (1990) (238)
Mössbauer and electron paramagnetic resonance studies of horseradish peroxidase and its catalytic intermediates. (1984) (178)
Chloroperoxidase compound I: Electron paramagnetic resonance and Mössbauer studies. (1984) (174)
Chloroperoxidase. VII. Classical peroxidatic, catalatic, and halogenating forms of the enzyme. (1970) (165)
Horseradish peroxidase compound I: evidence for spin coupling between the heme iron and a ‘free’ radical (1979) (162)
Highly enantioselective epoxidation of disubstituted alkenes with hydrogen peroxide catalyzed by chloroperoxidase (1993) (155)
Halohydrocarbon Synthesis by Bromoperoxidase (1978) (142)
Chloroperoxidase halogenation reactions. Chemical versus enzymic halogenating intermediates. (1982) (132)
Highly Enantioselective Epoxidation of 1,1-Disubstituted Alkenes Catalyzed by Chloroperoxidase (1995) (111)
Spectrum of chloroperoxidase compound I. (1980) (105)
Electron-nuclear double resonance of horseradish peroxidase compound I. Detection of the porphyrin pi-cation radical. (1981) (104)
Probing the heme iron coordination structure of pressure-induced cytochrome P420cam. (1996) (101)
A poly(dT)-stimulated ATPase activity associated with simian virus 40 large T antigen. (1979) (101)
Chloroperoxidase. 8. Formation of peroxide and halide complexes and their relation to the mechanism of the halogenation reaction. (1970) (100)
Studies of the ferric forms of cytochrome P-450 and chloroperoxidase by extended x-ray absotption fine structure. Characterization of the iron-nitrogen and iron-sulfur distances (1978) (98)
Chloroperoxidase, a janus enzyme. (2008) (95)
CRYSTALLINE CYTOCHROME B1 FROM ESCHERICHIA COLI. (1964) (94)
The P-450 nature of the carbon monoxide complex of ferrous chloroperoxidase. (1973) (90)
Chloroperoxidase. IX. The structure of compound I. (1972) (90)
Ligand and halide binding properties of chloroperoxidase: peroxidase-type active site heme environment with cytochrome P-450 type endogenous axial ligand and spectroscopic properties. (1986) (88)
Chloroperoxidase as Enantioselective Epoxidation Catalyst: An Efficient Synthesis of (R)-(-)-Mevalonolactone. (1996) (87)
Biological Chlorination VI. CHLOROPEROXIDASE: A COMPONENT OF THE β-KETOADIPATE CHLORINASE SYSTEM (1961) (84)
BROMOPEROXIDASES AND HALOGENATED LIPIDS IN MARINE ALGAE 1 (1980) (81)
Crystalline pyruvate oxidase from Escherichia coli. II. Activation by phospholipids. (1971) (79)
C. fumago chloroperoxidase is also a dehaloperoxidase: oxidative dehalogenation of halophenols. (2006) (78)
Studies on Cytochrome b562 of Escherichia coli I. PURIFICATION AND CRYSTALLIZATION OF CYTOCHROME b562 (1966) (77)
Oxygen-17 ENDOR of horseradish peroxidase compound I (1981) (76)
Highly Enantioselective Propargylic Hydroxylations Catalyzed by Chloroperoxidase (1999) (74)
On the mechanism of inhibition of enzymatic halogenation by antithyroid agents. (1962) (72)
Chemical nature of the porphyrin pi cation radical in horseradish peroxidase compound I. (1983) (71)
Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue. (1999) (70)
6 – Peroxidases, Catalases, and Chloroperoxidase (1979) (70)
Crystalline pyruvate oxidase from Escherichia coli. 3. Phospholipid as an allosteric effector for the enzyme. (1971) (67)
Utilization of peroxide and its relevance in oxygen insertion reactions catalyzed by chloroperoxidase. (2001) (65)
Mössbauer investigations of chloroperoxidase and its halide complexes. (1973) (65)
Rapid freeze-quench ENDOR study of chloroperoxidase compound I: the site of the radical. (2006) (64)
Purification and properties of bromoperoxidase from Penicillus capitatus. (1981) (63)
Enantioselective Epoxidation of ω-Bromo-2-methyl-1-alkenes Catalyzed by Chloroperoxidase. Effect of Chain Length on Selectivity and Efficiency (1997) (63)
Crystalline flavin pyruvate oxidase from Escherichia coli. I. Isolation and properties of the flavoprotein. (1966) (63)
Chiral synthons via chloroperoxidase catalysis (1998) (63)
Synthesis of brominated heptanones and bromoform by a bromoperoxidase of marine origin. (1981) (62)
The reaction of chlorite with horseradish peroxidase and chloroperoxidase. Enzymatic chlorination and spectral intermediates. (1974) (61)
LIPOIC ACID DEHYDROGENASE: THE FUNCTION OF E. COLI FRACTION B* (1953) (60)
Chloroperoxidase. IV. Evidence for an ionic electrophilic substitution mechanism. (1967) (59)
The detection of two electron paramagnetic resonance radical signals associated with chloroperoxidase compound I. (1982) (56)
Oxidation of horseradish peroxidase compound II to compound I. (1979) (56)
[55] Purification of chloroperoxidase from Caldariomyces fumago (1978) (55)
An electron paramagnetic resonance study of the high and low spin forms of chloroperoxidase. (1980) (54)
Activation of pyruvate oxidase by monomeric and micellar amphiphiles. (1978) (54)
Expression of Batis maritima methyl chloride transferase in Escherichia coli. (1999) (52)
Directed Evolution of Chloroperoxidase for Improved Epoxidation and Chlorination Catalysis (2001) (52)
Mechanism of the chlorination reaction catalyzed by horseradish peroxidase with chlorite. (1979) (51)
AN ENZYMATIC CHLORINATION REACTION (1959) (51)
Letter: Chloroperoxidase. Evidence for P-450 type heme environment from magnetic circular dichroism spectroscopy. (1976) (50)
Mössbauer investigations of high-spin ferrous heme proteins. II. Chloroperoxidase, horseradish peroxidase, and hemoglobin. (1975) (50)
Examining the Role of Glutamic Acid 183 in Chloroperoxidase Catalysis* (2003) (49)
Resonance Raman studies of isotopically labeled chloroperoxidase. (1986) (45)
Biological chlorination. III. beta-Ketoadipate chlorinase: a soluble enzyme system. (1959) (44)
Transient Heme N-Alkylation of Chloroperoxidase by Terminal Alkenes and Alkynes (1995) (44)
Identification of the fifth axial heme ligand of chloroperoxidase. (1988) (44)
cDNA cloning of Batis maritima methyl chloride transferase and purification of the enzyme. (1998) (43)
Kinetics of two-electron oxidations by the compound I derivative of chloroperoxidase, a model for cytochrome P450 oxidants. (2006) (43)
Oxidation-reduction potential measurements on chloroperoxidase and its complexes. (1976) (42)
Preparation and properties of ferrous chloroperoxidase complexes with dioxygen, nitric oxide, and an alkyl isocyanide. Spectroscopic dissimilarities between the oxygenated forms of chloroperoxidase and cytochrome P-450. (1985) (42)
Chemical modification of chloroperoxidase with diethylpyrocarbonate. Evidence for the presence of an essential histidine residue. (1990) (41)
Kinetic analysis of compound I formation and the catalatic activity of chloroperoxidase. (1981) (40)
Cloning and sequencing of chloroperoxidase cDNA. (1986) (40)
Asymmetric epoxidation of functionalized cis-olefins catalyzed by chloroperoxidase (1999) (39)
Chloroperoxidase: P-450 type absorption in the absence of sulfhydryl groups. (1975) (39)
Probing the heme iron coordination structure of alkaline chloroperoxidase. (1996) (39)
Resonance Raman investigations of chloroperoxidase, horseradish peroxidase, and cytochrome c using Soret band laser excitation. (1979) (38)
Chloroperoxidase generation of singlet Δ molecular oxygen observed directly by spectroscopy in the 1- to 1.6-μm region (1983) (38)
BIOLOGICAL CHLORINATION. IV. PEROXIDATIVE NATURE OF ENZYMATIC CHLORINATION1 (1959) (38)
Engineering chloroperoxidase for activity and stability (2001) (37)
Occurrence of fatty acid chlorohydrins in jellyfish lipids. (1977) (37)
BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (36)
On the mechanism of alpha-oxoglutarate oxidation in Escherichia coli. (1961) (35)
Single strand DNA binding of simian virus 40 tumor antigen. (1979) (35)
The reaction of chloroperoxidase with chlorite and chlorine dioxide. (1981) (35)
1-Iodo-3,3-dibromo-2-heptanone, 1,1,3,3-tetrabromo-2-heptanone, and related compounds from the red alga Bonnemaisonia hamifera (1975) (34)
The generation of a hyperporphyrin spectrum upon thiol binding to ferric chloroperoxidase. Further evidence of endogenous thiolate ligation to the ferric enzyme. (1984) (34)
Epoxidation of indene by chloroperoxidase (2000) (34)
Role for endonuclease I in the transmission process of colicin E 2 . (1972) (34)
A resolution of the Escherichia coli pyruvate dehydrogenase complex. (1961) (33)
Heme sulfuric anhydrides. II. Properties of heme models prepared from mesoheme sulfuric anhydrides. (1970) (33)
X-ray Absorption Near Edge Studies of Cytochrome P-450-CAM, Chloroperoxidase, and Myoglobin (1995) (33)
Oxygenated cytochrome P-450-CAM and chloroperoxidase: direct evidence for sulfur donor ligation trans to dioxygen and structural characterization using EXAFS spectroscopy (1986) (32)
The chloroperoxidase-catalyzed oxidation of thiols and disulfides to sulfenyl chlorides. (1974) (31)
Characterization of the proteolytic activation of pyruvate oxidase. Control by specific ligands and by the flavin oxidation-reduction state. (1977) (31)
Chemistry and functions of colicins (1973) (31)
CHEMISTRY OF PEROXIDASE INTERMEDIATES * (1975) (31)
Post-translational modifications of chloroperoxidase from Caldariomyces fumago. (1987) (30)
Molecular iodine as an obligate intermediate in the iodination of tyrosine by chloroperoxidase. (1969) (30)
Chloroperoxidase-mediated asymmetric epoxidation. Synthesis of (R)-dimethyl 2-methylaziridine-1,2-dicarboxylate—a potential α-methylamino acid synthon (1997) (30)
Highly Enantioselective Epoxidation of Disubstituted Alkenes with Hydrogen Peroxide Catalyzed by Chloroperoxidase. (1993) (30)
The ferric-hydroperoxo complex of chloroperoxidase. (2007) (28)
Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid. (1959) (28)
Reactivation of the lipid-depleted pyruvate oxidase system from Escherichia coli with cell envelope neutral lipids. (1975) (28)
Heme sulfuric anhydrides. I. Synthesis and reactions of mesoheme sulfuric anhydride. (1970) (28)
Characterization of the oxidized states of bromoperoxidase. (1985) (27)
High-pressure-assisted reconstitution of recombinant chloroperoxidase. (1995) (27)
The intriguing enhancement of chloroperoxidase mediated one-electron oxidations by azide, a known active-site ligand. (2011) (26)
Characterization of the catalytic properties of bromoperoxidase (1989) (26)
Structure of the modified heme in allylbenzene-inactivated chloroperoxidase determined by Q-band CW and pulsed ENDOR (1997) (26)
Isolation and nucleotide sequence of the chloroperoxidase gene from Caldariomyces fumago (1988) (26)
Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase* 210 (2003) (25)
Conversion of α-amino acids and peptides to nitriles and aldehydes by bromoperoxidase (1985) (25)
Flavoprotein-catalyzed pyruvate oxidation in Lactobacillus delbrueckii. (1954) (24)
Mössbauer and electron paramagnetic resonance studies of chloroperoxidase following mechanism-based inactivation with allylbenzene. (1996) (24)
Oxygen-17 nuclear magnetic resonance spectroscopic studies of carbonmonoxyperoxidases. (1988) (24)
Activation of Escherichia coli pyruvate oxidase enhances the oxidation of hydroxyethylthiamin pyrophosphate. (1991) (24)
ENDOR determination of heme ligation in chloroperoxidase and comparison with cytochrome P-450Cam (1994) (23)
Unusual propargylic oxidations catalyzed by chloroperoxidase. (1998) (23)
Resonance Raman spectra of chloroperoxidase. (1976) (23)
The amino acid sequence of cytochrome b562 of Escherichiacoli (1968) (22)
BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN. (1963) (22)
A colorimetric method for detection and quantification of chlorinating activity of hemeperoxidases. (2006) (22)
Role of flavin in acetoin production by two bacterial pyruvate oxidases. (1993) (21)
Role of the divalent metal cation in the pyruvate oxidase reaction. (1982) (21)
Electron paramagnetic resonance investigations of exogenous ligand complexes of low-spin ferric chloroperoxidase: further support for endogenous thiolate ligation to the heme iron. (1991) (21)
Isolation of directed evolution mutants of chloroperoxidase resistant to suicide inactivation by primary olefins (2000) (21)
Method for Determination of Oxygen-18 Content of Inorganic Phosphate (1958) (21)
A kinetic epoxidation assay for chloroperoxidase. (1999) (21)
Zero-field splitting of Fe3+ in horseradish peroxidase and of Fe4+ in horseradish peroxidase compound I from electron spin relaxation data. (1983) (21)
Development of semi-continuous and continuous flow bioreactors for the high level production of chloroperoxidase (1989) (20)
Broad-line nuclear magnetic resonance studies of chloroperoxidase. (1976) (20)
Intricenyne and related halogenated compounds from Laurencia intricata (1978) (19)
The peroxidation of molecular iodine to iodate by chloroperoxidase. (1968) (19)
Isolation and characterization of horseradish peroxidase compound X. (1982) (19)
Purification of chloroperoxidase from Caldariomyces fumago. (1978) (18)
Phosphine binding as a structural probe of the chloroperoxidase active site: spectroscopic evidence for endogenous thiolate ligation to the heme iron (1985) (18)
Compound X. An intermediate in enzymatic halogenation. (1976) (18)
Studies on cytochrome b562 of Escherichia coli. II. Reconstitution of cytochrome b562 from apoprotein and hemin. (1967) (18)
Characterization of the α-peptide released upon protease activation of pyruvate oxidase (1985) (17)
A rearranged dibromotyrosine metabolite from verongia aurea (1975) (17)
Reconstitution of native Escherichia coli pyruvate oxidase from apoenzyme monomers and FAD. (1982) (17)
A Lifetime of Playing with Enzymes (2010) (16)
The Oxygen Exchange Reaction Catalyzed by the Succinic-thiokinase1 (1957) (16)
A specific DNA unwinding activity associated with SV40 large T antigen. (1980) (16)
Isolation and characterization of the protease-activated form of pyruvate oxidase. Evidence for a conformational change in the environment of the flavin prosthetic group. (1983) (16)
Crystallization and properties of glutamate decarboxylase from Escherichia coli strain w+. (1967) (16)
A kinetic study of the binding of carbon monoxide to ferrous chloroperoxidase. (1982) (15)
Protein bromination by bromoperoxidase from Penicillus capitatus. (1984) (15)
Iodination of zeta protein by lactoperoxidase. Chloroperoxidase and chloramine T. (1976) (15)
Molecular parameters of 6-methylsalicylic acid synthetase from gel filtration and sucrose density gradient centrifugation. (1968) (15)
A single-step large-scale purification of pyruvate oxidase. (1987) (14)
Purification and characterization of culture-derived exoantigens of Plasmodium falciparum. (1985) (14)
Fructose induces and glucose represses chloroperoxidase mRNA levels. (1986) (13)
Escherichia coli pyruvate oxidase: interaction of a peripheral membrane protein with lipids. (1982) (12)
[84] Iodination of tyrosine by chloroperoxidase; preparation of chloroperoxidase (Caldariomyces fumago) (1970) (12)
Highly Enantioselective Propargylic Hydroxylations Catalyzed by Chloroperoxidase. (1999) (12)
Isolation of a heme crevice peptide from affinity-labeled horseradish peroxidase. (1980) (12)
Identification of the high-affinity lipid binding site in Escherichia coli pyruvate oxidase. (1986) (12)
Characterization of Laurencia Species by Gas Chromatography-Mass Spectrometry (1979) (11)
Mother Nature likes some halogenated compounds. (1982) (11)
Crystallographic study of cytochrome b562 from Escherichia coli (1972) (11)
Molecular structure of acetoxyintricatol: A new bromo compound from . (1974) (11)
Hypersensitive radical probe studies of chloroperoxidase-catalyzed hydroxylation reactions. (1998) (11)
[75] Phosphate-linked pyruvic acid oxidase from Lactobacillus delbrückii: (Bacillus acidificans longissimus, Lafar) Pyruvate + P + O2 → Ac∼P -t- CO2 + H2O2 (1955) (10)
Coupling between phosphorylation and flavin adenine dinucleotide reduction with the pyruvate oxidase of L. delbrueckii enzyme. (1961) (10)
Inhibition of Colicin E2 Activity by Bacterial Lipopolysaccharide (1970) (10)
Synthesis of D,L-Caldariomycin1 (1961) (10)
Systematic trends in the spectroscopic properties of low-spin ferric ligand adducts of cytochrome P-450 and chloroperoxidase : the transition from normal to hyper spectra (1992) (10)
[67] The preparation and properties of cytochrome b562 from Escherichia coli (1967) (9)
The active sites of chloroperoxidase and cytochrome P-450-CAM: Comparative spectroscopic and ligand binding properties (1983) (8)
ACTIVATION OF A FERRICYANIDE LINKED PYRUVATE OXIDASE BY α-TOCOPHEROL ESTERS (1957) (8)
[66] The preparation of bacterial cytochrome b1 (1967) (8)
Cytochrome P-450 and peroxidase chemistry. (1994) (8)
Solubilization and enzymic activity of bacterial cytochrome b. (1960) (7)
Binding of pyruvate oxidase α-peptide to phospholipid vesicles (1987) (7)
Biological Chlorination (7)
[51] Pyruvic (cytochrome b1) dehydrogenase (crystalline) (1966) (6)
STUDIES ON THE MECHANISM OF ACTION OF COLICIN E2 (1973) (6)
Reconstitution of the lipid-depleted pyruvate oxidase system of Escherichia coli: the palmitic acid effect. (1984) (6)
Chloroperoxidase generation of singlet Delta molecular oxygen observed directly by spectroscopy in the 1- to 1.6-mum region. (1983) (6)
Reconstitution of Colicin E2-Induced Deoxyribonucleic Acid Degradation in Spheroplast Preparations (1973) (6)
Enantioselective Epoxidation of ω‐Bromo‐2‐methyl‐1‐alkenes Catalyzed by Chloroperoxidase. Effect of Chain Length on Selectivity and Efficiency. (1997) (6)
Minimum requirements for protease activation of flavin pyruvate oxidase. (1991) (5)
Characterization of the alpha-peptide released upon protease activation of pyruvate oxidase. (1985) (5)
A method for the rapid determination of trace organic halogens in lipids. (1977) (5)
Studies on cytochrome b-562 of Escherichia coli. I. Purification and crystallization of cytochrome b-562. (1966) (5)
Trypsin activation of a ferricyanide-linked pyruvic acid oxidation. (1957) (5)
Enzymatic Steps in Alpha-Keto Acid Oxidation (1953) (4)
The synthesis and assay of high specific acitivty of 14 C-trimethyloxonium tetrafluoroborate. (1971) (4)
Modification of the Cary Model 14 recording spectrophotometer for low-temperature spectroscopy. (1965) (4)
Chemical and transient state kinetic studies on the formation and decomposition of horseradish peroxidase compounds XI and XII. (1991) (4)
Crystallization and preliminary X-ray data for chloroperoxidase. (1982) (4)
Mechanism of the inhibition of enzymatic halogenation by antithyroid agents. (1966) (4)
A crystalline flavin pyruvate oxidase. (1961) (3)
Asymmetric Epoxidation of Functionalized cis‐Olefins Catalyzed by Chloroperoxidase. (1999) (3)
Application of I mossbauer effect to biological systems: studies with heme models. (1970) (3)
[120] Glutamate decarboxylase (Escherichia coli) (1970) (3)
Activation of Pyruvate Oxidase and Interaction with Membrane Components (1982) (3)
Conversion of alpha-amino acids and peptides to nitriles and aldehydes by bromoperoxidase. (1985) (2)
The amino acid sequence of cytochrome b562 of Escherichia coli. (1968) (2)
Highly Enantioselective Epoxidation of 1,1-Disubstituted Alkenes Catalyzed by Chloroperoxidase. (1995) (2)
Binding of pyruvate oxidase alpha-peptide to phospholipid vesicles. (1987) (2)
CHEMICAL NATURE AND REACTION OF CHLOROPEROXIDASE COMPOUND I (1972) (2)
Crystalline Cytochrome b, from Escherichia coZi* (2003) (1)
Purification of cytochrome b1 from Escherichia coli. (1978) (1)
Free Radical Nature of Compound I (1982) (1)
Isolation of the active site of cytochrome c by reverse-phase high-performance liquid chromatography (1990) (1)
On the Mechanism of et-Oxoglutarate Oxidation in Escherichia coli (2005) (1)
Affinity labeling of myoglobin with mesoheme sulfuric anhydride. (1970) (1)
Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase* □ S (2003) (0)
Phosphine Binding as a Structural Probe of the Chloroperoxidase Active Sitc: Spectroscopic Evidence for Endogenous Thiolate Ligation to the Heme Iron (1986) (0)
Engineering chloroperoxidase for enhanced catalytic activity (2001) (0)
Electron-Paramagnetic-Resonance of Allylbenzene-Inactivated Chloroperoxidase and a Possible Intermediate in Reactivation (1995) (0)
Method for immobilizing antimicrobial emnen (1977) (0)
Mesoheme sulfuric anhydride as a heme protein structure probe reaction with cytochrome b 562. (1970) (0)
Crystallographic study of cytochrome b 562 from Escherichia coli. (1972) (0)
Oxygenated Cytochrome P-450-CAM and Chloroperoxidase: Direct Evidence for Sulfur Donor Ligation trans to Dioxygen and Structural Characterization Using EXAFS Spectroscopy. (1987) (0)
Mechanism-based inactivation of chloroperoxidase with terminal olefins. Identification of an intermediate in the spontaneous enzyme reactivation (1995) (0)
Ligands in Heme Iron in Chloroperoxidase: An Electron Paramagnetic Resonance Study (1982) (0)
MOLECULAR STRUCTURE OF ACETOXYINTRICATOL, A NEW COMPOUND FROM LAURENCIA INTRICATA (1974) (0)
Inhibition ofColicin E2Activity byBacterial Lipopolysacchari de (1970) (0)

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