Luciano Rossetti
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Luciano Rossetti's AcademicInfluence.com Rankings
Luciano Rossettibiology Degrees
Biology
#12755
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#16253
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Molecular Biology
#2098
World Rank
#2130
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Biochemistry
#2206
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#2351
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Biology
Luciano Rossetti's Degrees
- Masters Molecular Biology Stanford University
Why Is Luciano Rossetti Influential?
(Suggest an Edit or Addition)Luciano Rossetti's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. (2000) (1082)
- Mechanisms of fatty acid-induced inhibition of glucose uptake. (1994) (1021)
- Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. (2001) (910)
- Hypothalamic insulin signaling is required for inhibition of glucose production (2002) (882)
- A nutrient-sensing pathway regulates leptin gene expression in muscle and fat (1998) (869)
- Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. (1987) (789)
- Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. (2003) (763)
- Regulation of Fasted Blood Glucose by Resistin (2004) (725)
- Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats (2002) (684)
- Central administration of oleic acid inhibits glucose production and food intake. (2002) (651)
- SirT1 gain of function increases energy efficiency and prevents diabetes in mice. (2008) (637)
- Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists* (2006) (636)
- Hypothalamic KATP channels control hepatic glucose production (2005) (613)
- Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? (2002) (577)
- Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production (2003) (540)
- Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver. (2007) (537)
- Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. (2003) (536)
- A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. (2004) (528)
- Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice (2003) (515)
- Hypothalamic sensing of fatty acids (2005) (450)
- Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake (2006) (440)
- Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis (2005) (425)
- Surgical removal of visceral fat reverses hepatic insulin resistance. (1999) (392)
- Central melanocortin receptors regulate insulin action. (2001) (368)
- A brain-liver circuit regulates glucose homeostasis. (2005) (367)
- Leptin selectively decreases visceral adiposity and enhances insulin action. (1997) (365)
- Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. (1987) (358)
- Role of resistin in diet-induced hepatic insulin resistance. (2004) (357)
- Overfeeding rapidly induces leptin and insulin resistance. (2001) (348)
- Short Term Effects of Leptin on Hepatic Gluconeogenesis and in Vivo Insulin Action* (1997) (336)
- Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. (1995) (335)
- Regulation of Blood Glucose by Hypothalamic Pyruvate Metabolism (2005) (321)
- Role of the glucosamine pathway in fat-induced insulin resistance. (1997) (316)
- Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms (2008) (307)
- Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance. (2006) (283)
- Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats. (1990) (279)
- In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. (1995) (279)
- Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. (1994) (276)
- Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. (1998) (254)
- Molecular disruption of hypothalamic nutrient sensing induces obesity (2006) (236)
- Intracerebroventricular Leptin Regulates Hepatic but Not Peripheral Glucose Fluxes* (1998) (228)
- Minireview: nutrient sensing and the regulation of insulin action and energy balance. (2003) (220)
- Abnormal glucose homeostasis due to chronic hyperresistinemia. (2004) (216)
- Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. (2006) (214)
- Disulfide-Dependent Multimeric Assembly of Resistin Family Hormones (2004) (213)
- Critical role of STAT3 in leptin's metabolic actions. (2006) (210)
- Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes. (1993) (207)
- Hypothalamic Responses to Long-chain Fatty Acids Are Nutritionally Regulated* (2004) (188)
- Oral Vanadyl Sulfate Improves Insulin Sensitivity in NIDDM but Not in Obese Nondiabetic Subjects (1996) (184)
- Decreased in vivo glucose uptake but normal expression of GLUT1 and GLUT4 in skeletal muscle of diabetic rats. (1991) (183)
- Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. (1991) (174)
- Glucose Regulates in Vivo Glucose-6-phosphatase Gene Expression in the Liver of Diabetic Rats (*) (1996) (173)
- Role of glucokinase and glucose-6-phosphatase in the acute and chronic regulation of hepatic glucose fluxes by insulin. (1993) (171)
- Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats. (2008) (169)
- Central leptin acutely reverses diet-induced hepatic insulin resistance. (2005) (159)
- Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins (2007) (151)
- Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons (2009) (149)
- Leptin resistance during aging is independent of fat mass. (2002) (146)
- Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. (2001) (143)
- Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene (*) (1995) (139)
- The Irs1 Branch of the Insulin Signaling Cascade Plays a Dominant Role in Hepatic Nutrient Homeostasis (2009) (138)
- Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus. (1998) (136)
- In Vivo Insulin Resistance Induced by Amylin Primarily Through Inhibition of Insulin-Stimulated Glycogen Synthesis in Skeletal Muscle (1991) (136)
- Induction of Hepatic Glucose-6-Phosphatase Gene Expression by Lipid Infusion (1997) (131)
- Perspective: Hexosamines and nutrient sensing. (2000) (131)
- The Tissue Concentration of UDP-N-acetylglucosamine Modulates the Stimulatory Effect of Insulin on Skeletal Muscle Glucose Uptake* (1997) (129)
- Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle. (1989) (122)
- Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. (2005) (118)
- Effect of metformin treatment on insulin action in diabetic rats: in vivo and in vitro correlations. (1990) (116)
- Small increases in insulin inhibit hepatic glucose production solely caused by an effect on glycogen metabolism. (2001) (114)
- Melanocortin-independent Effects of Leptin on Hepatic Glucose Fluxes* (2004) (113)
- In vivo glucose metabolism in the awake rat: tracer and insulin clamp studies. (1987) (112)
- Effect of dietary protein on in vivo insulin action and liver glycogen repletion. (1989) (110)
- Hypothalamic resistin induces hepatic insulin resistance. (2007) (107)
- Glucose toxicity: the implications of hyperglycemia in the pathophysiology of diabetes mellitus. (1995) (98)
- Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene. (1997) (96)
- Predominant role of gluconeogenesis in the hepatic glycogen repletion of diabetic rats. (1992) (95)
- Adiponectin Resistance Exacerbates Insulin Resistance in Insulin Receptor Transgenic/Knockout Mice (2007) (94)
- Carbon Flux via the Pentose Phosphate Pathway Regulates the Hepatic Expression of the Glucose-6-phosphatase and Phosphoenolpyruvate Carboxykinase Genes in Conscious Rats* (1998) (92)
- Relationship between changes in body composition and insulin responsiveness in models of the aging rat. (1995) (87)
- Functional analysis of a conditionally transformed pancreatic beta-cell line. (1998) (87)
- The effect of leptin on Lep expression is tissue-specific and nutritionally regulated (1999) (86)
- Quantitative analysis of glycogen repletion by nuclear magnetic resonance spectroscopy in the conscious rat. (1987) (83)
- Identification of a biochemical link between energy intake and energy expenditure. (2002) (81)
- Fructose improves the ability of hyperglycemia per se to regulate glucose production in type 2 diabetes. (2002) (79)
- Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance. (2001) (79)
- Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice. (2005) (72)
- 13C NMR studies of glycogen turnover in the perfused rat liver. (1988) (70)
- Glucosamine-Induced Inhibition of Liver Glucokinase Impairs the Ability of Hyperglycemia to Suppress Endogenous Glucose Production (1996) (69)
- Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production. (1993) (66)
- Hyperglycemia modulates angiotensinogen gene expression. (2001) (65)
- Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects. (2002) (64)
- Prevention of insulin resistance and diabetes in mice heterozygous for GLUT4 ablation by transgenic complementation of GLUT4 in skeletal muscle. (1999) (64)
- Quantitation of glycolysis and skeletal muscle glycogen synthesis in humans. (1993) (64)
- Metabolic Effects of IGF-I in Diabetic Rats (1991) (63)
- Role of Transcription Factor NFAT in Glucose and Insulin Homeostasis (2006) (63)
- Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats (2011) (63)
- Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation. (2000) (62)
- Insulinomimetic Properties of Trace Elements and Characterization of Their In Vivo Mode of Action (1990) (60)
- Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. (2002) (59)
- Physiological Role of Cholecystokinin in Meal-Induced Insulin Secretion in Conscious Rats: Studies With L 364718, A Specific Inhibitor of CCK-Receptor Binding (1987) (58)
- Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus. (1994) (56)
- Hepatic Overexpression of Insulin-like Growth Factor-II in Adulthood Increases Basal and Insulin-stimulated Glucose Disposal in Conscious Mice (*) (1996) (53)
- Identification and characterization of a novel phosphorylation site on the GluR1 subunit of AMPA receptors (2007) (53)
- Normalization of Insulin Sensitivity With Lithium in Diabetic Rats (1989) (53)
- Hypothalamic Protein Kinase C Regulates Glucose Production (2008) (51)
- In vivo insulin action in genetic models of hypertension. (1992) (49)
- Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. (2010) (49)
- Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats. (1996) (49)
- Characterization of the Serum from a Patient with Insulin Resistance and Hypoglycemia: Evidence for Multiple Populations of Insulin Receptor Antibodies with Different Receptor Binding and Insulin-mimicking Activities (1984) (48)
- Erratum: Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects (Diabetes (1996) 45 (659-666)) (1996) (47)
- Increased Hexosamine Availability Similarly Impairs the Action of Insulin and IGF-1 on Glucose Disposal (1996) (47)
- Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action. (1999) (46)
- Intracerebroventricular leptin regulates hepatic cholesterol metabolism. (2004) (46)
- Discordant Effects of Glucosamine on Insulin-stimulated Glucose Metabolism and Phosphatidylinositol 3-Kinase Activity* (1999) (39)
- Hyperglycemia Markedly Enhances Skeletal Muscle Glycogen Synthase Activity in Diabetic, But Not in Normal Conscious Rats (1992) (39)
- Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2 (2008) (38)
- Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. (1997) (36)
- Type 2 diabetes — who is conducting the orchestra? (1998) (36)
- Counterregulation of Hypoglycemia: Skeletal Muscle Glycogen Metabolism During Three Hours of Physiological Hyperinsulinemia in Humans (1995) (35)
- Effects of fasting and glucocorticoids on hepatic gluconeogenesis assessed using two independent methods in vivo. (2002) (34)
- Effect of insulin on renal potassium metabolism. (1987) (34)
- Chronic in vivo hyperglycemia impairs phosphoinositide hydrolysis and insulin release in isolated perifused rat islets. (1990) (34)
- Isocratic high-performance liquid chromatographic determination of the concentration and specific radioactivity of phosphoenolpyruvate and uridine diphosphate glucose in tissue extracts. (1989) (33)
- Multiple metabolic effects of CGRP in conscious rats: role of glycogen synthase and phosphorylase. (1993) (32)
- Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice. (1995) (31)
- Mechanism by which calcitonin gene-related peptide antagonizes insulin action in vivo. (1991) (30)
- Neural and pancreatic influences on net hepatic glucose uptake and glycogen synthesis. (1996) (30)
- Decreased visceral adiposity accounts for leptin effect on hepatic but not peripheral insulin action. (1999) (30)
- Hypothalamic sensing of circulating lactate regulates glucose production (2008) (29)
- Effect of in vivo vanadate treatment on insulin receptor tyrosine kinase activity in partially pancreatectomized diabetic rats. (1990) (27)
- Fructose amplifies counterregulatory responses to hypoglycemia in humans. (2002) (27)
- Circulating anti-insulin receptor antibodies in a patient suffering from lupus nephritis and hypoinsulinemic hypoglycaemia. (1983) (26)
- Aging does not contribute to the decline in insulin action on storage of muscle glycogen in rats. (2000) (26)
- The effect of age-dependent increase in fat mass on peripheral insulin action is saturable. (1998) (24)
- Differential effect of hyperglycemia and hyperinsulinemia on pathways of hepatic glycogen repletion. (1991) (23)
- Effects of fasting on hepatic and peripheral glucose metabolism in conscious rats with near-total fat depletion. (1995) (23)
- Effect of hepatic nerves on disposition of an intraduodenal glucose load. (1993) (23)
- Hyperamylinemia is associated with hyperinsulinemia in the glucose-tolerant, insulin-resistant offspring of two Mexican-American non-insulin-dependent diabetic parents. (1997) (20)
- Red Blood Cell Age, Pyruvate Kinase Activity, and Insulin Receptors: Evidence that Monocytes and RBCs May Behave Differently (1983) (20)
- Insulin resistance and its role in the pathogenesis of type 2 diabetes (2011) (17)
- Influence of the route of glucose administration on hepatic glycogen repletion. (1989) (16)
- Increased insulin sensitivity in the high sodium one-kidney, one figure-8 hypertensive rat. (1992) (13)
- A new piece in the diabetes puzzle (2002) (9)
- Hormone-independent activation of EGP during hypoglycemia is absent in type 1 diabetes mellitus. (2000) (9)
- Did a muscle fuel gauge conquer the brain? (2006) (9)
- Inhibition of insulin and epidermal growth factor (EGF) receptor autophosphorylation by a human polyclonal IgG. (1985) (9)
- Human autoantibodies directed against the human, but not the rat, insulin receptor. (1985) (8)
- Glycogen synthase activity in two rat models of hypertension. (1995) (8)
- Increased lipid oxidation but normal muscle glycogen response to epinephrine in humans with IDDM. (1996) (7)
- Einstein's institute for aging research: collaborative and programmatic approaches in the search for successful aging (2004) (6)
- Characterization of differences in insulin receptors from young and old red blood cells (1987) (4)
- Disruption of one allele of the murine glut 4 gene causes marked resistance to the action of insulin (1996) (4)
- Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats. Diabetes 2011;60:2691–2700 (2017) (2)
- Effects of beta-adrenergic blockade on insulin-mediated glucose disposal in hypertensive and normotensive rats. (1996) (1)
- Hypothalamic Protein Kinase C Regulates Glucose (2008) (1)
- Role of Transcription Factor NFAT in Glucose and Insulin Homeostasis (cid:1) (2006) (0)
- the doxorubicine-induced Cardiorenohepatic syndrome reflects severity of decompensated heart failure and is related with worse prognosis (0)
- 27 LEPTIN REGULATES ADIPOSE TISSUE LIPOGENESIS THROUGH HYPOTHALAMIC PATHWAYS THAT REQUIRE PI3K BUT ARE INDEPENDENT OF STAT3 SIGNALING. (2007) (0)
- Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. (1997) (0)
- Effects of β -adrenergic blockade on insulin-mediated glucose disposal in hypertensive and normotensive rats (1996) (0)
- Prevention of Fat Accretion through Puberty restores Insulin Action on Glycogen Synthesis to Prepubertal Levels in Conscious Rats. † 373 (1997) (0)
- with a disrupted glucokinase allele Abnormal regulation of HGP by hyperglycemia in mice (2016) (0)
- Hypoglycemia reduces insulin sensitivity in the liver (1992) (0)
- Hepatic glycogen signal detection in rats using Gaussian-weighted phase encoding C13 MR spectroscopic imaging (2007) (0)
- Erratum: Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion (Diabetes (1997) 46 (153-157)) (1997) (0)
- Functional MRI of Hypothalamic Responses to Circulating Glucose and Fatty Acids (2005) (0)
- Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol’s Effects on Insulin Action in Rats. Diabetes 2011;60:2691–2700 (2017) (0)
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