Lawrence S. Kaminsky

Lawrence S. Kaminsky's AcademicInfluence.com Rankings

Biology

#13659

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#17214

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Molecular Biology

#2331

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#2366

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Biochemistry

#2409

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#2560

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Biology

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Lawrence S. Kaminsky's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Cytochrome P450 (1993) (1119)
Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone. (1982) (924)
Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. (2003) (810)
Human P450 metabolism of warfarin. (1997) (746)
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism. (1996) (641)
Characterization of human small intestinal cytochromes P-450. (1999) (358)
Human cytochromes P450 (1999) (303)
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA. (1992) (245)
The small intestine as a xenobiotic-metabolizing organ. (2003) (230)
Small intestinal cytochromes P450. (1991) (222)
Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae. (1990) (205)
Expression of cytochromes P450 in human breast tissue and tumors. (1996) (195)
Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes. (1983) (190)
Optimization of Dnase I removal of contaminating DNA from RNA for use in quantitative RNA-PCR. (1996) (184)
Characterization of purified human recombinant cytochrome P4501A1-Ile462 and -Val462: assessment of a role for the rare allele in carcinogenesis. (1996) (159)
Fluoride: benefits and risks of exposure. (1990) (150)
Purification and characterization of microsomal cytochrome P-450s. (1982) (148)
Correlation of human cytochrome P4502C substrate specificities with primary structure: warfarin as a probe. (1993) (144)
Metabolic characterization of the major human small intestinal cytochrome p450s. (2001) (142)
Effect of metals on polycyclic aromatic hydrocarbon induction of CYP1A1 and CYP1A2 in human hepatocyte cultures. (2001) (129)
Polycyclic aromatic hydrocarbon/metal mixtures: effect on PAH induction of CYP1A1 in human HEPG2 cells. (2001) (125)
Regulation of cytochrome P-450. Immunochemical quantitation of eight isozymes in liver microsomes of rats treated with polybrominated biphenyl congeners. (1983) (122)
Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures (1986) (120)
Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P-450. (1981) (115)
Correlations between polychlorinated biphenyl immunotoxicity, the aromatic hydrocarbon locus, and liver microsomal enzyme induction in C57BL/6 and DBA/2 mice. (1984) (113)
Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation. (1995) (113)
Influence of cytochrome P 450 polymorphisms on drug therapies : Pharmacogenetic , pharmacoepigenetic and clinical aspects (2007) (111)
Gene-Environment Interaction Signatures by Quantitative mRNA Profiling in Exfoliated Buccal Mucosal Cells (2004) (108)
Characterization of rat small intestinal cytochrome P450 composition and inducibility. (1996) (108)
Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe. (1995) (97)
Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors. (2003) (97)
Characterization of mouse small intestinal cytochrome P450 expression. (2003) (95)
[16] Production and application of antibodies to rat liver cytochrome P-450 (1981) (91)
Human cytochrome P-450 metabolism of retinals to retinoic acids. (2000) (88)
CYP1B1 expression in human lung. (2001) (88)
Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice. (2007) (86)
Cytochrome P-450 isozyme/isozyme functional interactions and NADPH-cytochrome P-450 reductase concentrations as factors in microsomal metabolism of warfarin. (1985) (82)
Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite. (2002) (78)
Biochemical applications of a quantitative high-pressure liquid chromatographic assay of warfarin and its metabolites. (1977) (77)
Rat small intestinal cytochromes P450 probed by warfarin metabolism. (1993) (73)
Comparison of different forms of purified cytochrome P-450 from rat liver by immunological inhibition of regio- and stereoselective metabolism of warfarin. (1980) (72)
16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5. (1998) (69)
Comparison of monooxygenase activities and cytochrome P-450 isozyme concentrations in human liver microsomes. (1986) (69)
Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice. (1999) (68)
Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. (2008) (67)
Induction of hepatic microsomal cytochrome P-450 by mirex and kepone. (1978) (65)
Influence of aging and induction of rat liver and kidney microsomal mixed function oxidase systems. (1980) (65)
Transgenic Mice with a Hypomorphic NADPH-Cytochrome P450 Reductase Gene: Effects on Development, Reproduction, and Microsomal Cytochrome P450 (2005) (64)
Regulation of cytochrome P4501A1 expression in rat small intestine. (1997) (64)
The molecular epidemiology of lung cancer. (1997) (62)
Thermodynamic studies of the opening of the heme crevice of ferricytochrome c. (1973) (62)
Regioselective and stereoselective hydroxylation of R and S warfarin by different forms of purified cytochrome P-450 from rabbit liver. (1978) (62)
Quantitative RNA-polymerase chain reaction-DNA analysis by capillary electrophoresis and laser-induced fluorescence. (1995) (61)
Evidence for functional and structural multiplicity of pregnenolone-16 alpha-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes. (1987) (59)
Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin. (1984) (57)
Inhibition of estrone sulfatase in human liver microsomes by quercetin and other flavonoids (1997) (57)
Identification of Cytochrome P450 Oxidoreductase Gene Variants That Are Significantly Associated with the Interindividual Variations in Warfarin Maintenance Dose (2011) (53)
An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine (2009) (51)
Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity. (1994) (48)
Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine (2007) (46)
Comparisons of warfarin metabolism by liver microsomes of rats treated with a series of polybrominated biphenyl congeners and by the component-purified cytochrome P-450 isozymes. (1983) (45)
Metabolism of dichlorobiphenyls by hepatic microsomal cytochrome P-450. (1980) (44)
Characterization of the cytochrome P450 CYP2J4: expression in rat small intestine and role in retinoic acid biotransformation from retinal. (1998) (44)
A Novel Method for the Quantitation of Warfarin and its Metabolites in Plasma (1979) (43)
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo. (1985) (42)
Alternative splicing of CYP2D mRNA in human breast tissue. (1997) (42)
Comparison of different forms of liver, kidney, and lung microsomal cytochrome P-450 by immunological inhibition of regio- and stereoselective metabolism of warfarin. (1979) (42)
Subchronic oral toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the guinea pig: comparisons with a PCB-containing transformer fluid pyrolysate. (1986) (40)
CDNA cloning, heterologous expression, and characterization of rat intestinal CYP2J4. (1997) (40)
Acute toxicity in guinea pigs and rabbits of soot from a polychlorinated biphenyl-containing transformer fire. (1982) (39)
Cholesterol uptake by egg-yolk phosphatidylcholine. (1971) (39)
Methionine sulfoxide cytochrome c. (1976) (37)
Cumene hydroperoxide-supported microsomal hydroxylations of warfarin--a probe of cytochrome P-450 multiplicity and specificity. (1979) (37)
Selective inhibition of warfarin metabolism by diltiazem in humans. (1991) (37)
Fluroxene (2,2,2-trifluoroethyl vinyl ether) mediated destruction of cytochrome P-450 in vitro. (1975) (36)
A new warfarin metabolite: structure and function. (1978) (36)
Phase II metabolism of warfarin in primary culture of adult rat hepatocytes. (1992) (36)
MECHANISMS OF ARSENITE-MEDIATED DECREASES IN BENZO[K]FLUORANTHENE-INDUCED HUMAN CYTOCHROME P4501A1 LEVELS IN HEPG2 CELLS (2005) (35)
The role of cytochrome P-450 in the toxicity of fluroxene (2,2,2-trifluoroethyl vinyl ether) anaesthesia in vivo. (1976) (34)
Composition of cytochrome P-450 isozymes from hepatic microsomes of C57BL/6 and DBA/2 mice assessed by warfarin metabolism, immunoinhibition, and immunoelectrophoresis with anti-(rat cytochrome P-450). (1984) (33)
Dichloromethyl compounds as mechanism-based inactivators of rat liver cytochromes P-450 in vitro. (1986) (32)
Teratology of 2,3,7,8-tetrachlorodibenzo-p-dioxin in a complex environmental mixture from the love canal. (1989) (32)
Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung, olfactory mucosa, and small intestine, but not in the heart. (2000) (32)
A complex of cardiac cytochrome c1 and cytochrome c. (1976) (29)
Determination of theophylline and its metabolites in rat liver microsomes and human urine by capillary electrophoresis. (1995) (29)
Acute toxicity of fluorinated ether anesthetics: role of 2,2,2-trifluoroethanol and other metabolites. (1983) (29)
Circular dichroism studies of the perturbations of cytochrome c by alcohols. (1972) (29)
Chemical and biological investigations of a transformer accident at Binghamton, NY (1985) (29)
Further investigations of the metabolism of fluroxene and the degradation of cytochromes P-450 in vitro. (1977) (28)
Iron ligands in different forms of ferricytochrome c: the 620-nm band as a probe. (1972) (28)
Comparisons of CYP2D messenger RNA splice variant profiles in human lung tumors and normal tissues. (1997) (27)
Some properties of mammalian cardiac cytochrome c1. (1975) (27)
Cytochromes P450 and cancer. (1999) (26)
Warfarin as a probe of cytochromes P-450 function. (1989) (25)
Effect of alcohols on the rate of autoxidation of ferrocytochrome c. (1971) (24)
Intracellular lactate dehydrogenase concentration as an index of cytotoxicity in rat hepatocyte primary culture (1988) (24)
Production and application of antibodies to rat liver cytochrome P-450. (1981) (24)
Analysis of oxidative warfarin metabolites by thermospray high-performance liquid chromatography/mass spectrometry. (1989) (24)
Caffeine based measures of CYP1A2 activity correlate with oral clearance of tacrine in patients with Alzheimer's disease. (1998) (24)
Plasma and cellular markers of 3′‐azido‐3′‐dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs (2007) (23)
The interaction of hepatic microsomal cytochrome P-450 with fluroxene (2,2,2-trifluoroethyl vinyl ether) in vitro. (1976) (23)
Subchronic exposure of mice to Love Canal soil contaminants. (1984) (22)
Effects of organic solvents on the spectrum of cytochrome C. (1969) (22)
Induction of CYP1A by benzo[k]fluoranthene in human hepatocytes: CYP1A1 or CYP1A2? (2001) (21)
The role of cytochrome P-450-inducing agents in potentiaing the toxicity of fluroxene (2,2,2-trifluoroethyl vinyl ether). (1980) (20)
Induction of CYP1A1 by beta-naphthoflavone in IEC-18 rat intestinal epithelial cells and potentiation of induction by dibutyryl cAMP. (1997) (20)
Regioselective hydroxylation of warfarin by cell suspension cultures of Catharanthus roseus (1993) (20)
Quantitation of CYP1A1 and 1B1 mRNA in polycyclic aromatic hydrocarbon-treated human T-47D and HepG2 cells by a modified bDNA assay using fluorescence detection. (2003) (20)
The effects of Love Canal soil extracts on maternal health and fetal development in rats. (1986) (20)
High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice (2009) (19)
Destruction of highly purified cytochromes P-450 associated with metabolism of fluorinated ether anesthetics. (1981) (18)
The Role of Trace Metals in Cytochrome P4501 Regulation (2006) (18)
Investigations of the posttranslational mechanism of arsenite‐mediated downregulation of human cytochrome P4501A1 levels: The role of heme oxygenase‐1 (2009) (18)
Detergents as probes of reconstituted rat liver cytochrome P-450 function. (1987) (18)
Induction of rat small intestinal cytochrome P-450 2J4. (1999) (17)
16 α-Hydroxylation of estrone by human cytochrome P 4503 A 4 / 5 (1998) (17)
Warfarin analog inhibition of human CYP2C9-catalyzed S-warfarin 7-hydroxylation. (1997) (17)
A complex of cytochrome c and mixed mitochondrial phospholipids. (1973) (17)
Fluorescence studies of cytochrome c1 and a cytochrome c1-cytochrome c complex. (1974) (16)
CYP 1 B 1 EXPRESSION IN HUMAN LUNG (2001) (15)
Metabolism of 2,2,2-trifluoroethanol and its relationship to toxicity. (1987) (15)
Potentiation of fluroxene (2,2,2-trifluoroethyl vinyl ether) toxicity with polychlorinated biphenyls. (1979) (14)
Selective inactivation by chlorofluoroacetamides of the major phenobarbital-inducible form(s) of rat liver cytochrome P-450. (1990) (14)
Subchronic oral toxicity in guinea pigs of soot from a polychlorinated biphenyl-containing transformer fire. (1983) (14)
High-performance liquid chromatography of polychlorinated biphenyls (1978) (14)
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. (1992) (14)
Differences in the functional interaction of two purified cytochrome P-450 isozymes with epoxide hydrolase. (1981) (14)
Effects of differential changes in rat hepatic and renal cytochrome P-450 concentrations on hepatotoxicity and nephrotoxicity of chloroform. (1981) (13)
Carbon monoxide as a probe for conformation changes of ferrocytochrome c. (1972) (13)
Azidowarfarin photoaffinity probes of purified rat liver cytochrome P4501A1. (1992) (12)
2,2,2-Trifluoroethanol intestinal and bone marrow toxicity: the role of its metabolism to 2,2,2-trifluoroacetaldehyde and trifluoroacetic acid. (1988) (12)
Binding of R and S warfarin to hepatic microsomal cytochrome P-450. (1977) (11)
Some properties of a cytochrome c-mixed mitochondrial phospholipid complex. (1974) (11)
POLYCYCLIC AROMATIC HYDROCARBON / METAL MIXTURES : EFFECT ON PAH INDUCTION OF CYP 1 A 1 IN HUMAN HEPG 2 CELLS (2001) (11)
Trifluorinated ether anesthetic lethality in rats: the role of bacterial infection. (1983) (10)
Nitrones. Part III. Photolysis of cyclic nitrones (1966) (10)
Fluorescence studies of a cytochrome C mixed phospholipid complex. (1973) (10)
Some properties of particles of egg-yolk phosphatidylcholine and cholesterol (1972) (9)
Role of hepatic microsomal cytochrome P-450 in the toxicity of fluorinated ether anesthetics. (1980) (9)
Effect of chloramphenicol administration in vivo on cytochrome P-450-dependent monooxygenase activities in liver microsomes from uninduced male rats. (1988) (8)
Determination of Metabolic Rates and Enzyme Kinetics (2007) (8)
Nitrones. Part VI. The pyrolysis of oxaziridines derived by photolysis of cyclic nitrones (1967) (8)
INDUCTION OF CYP 1 A 1 AND CYP 1 B 1 IN T-47 D HUMAN BREAST CANCER CELLS BY BENZO [ A ] PYRENE IS DIMINISHED BY ARSENITE (2002) (8)
Molecular orbital studies of epoxide stability of carcinogenic polycyclic aromatic hydrocarbon diol epoxides. (1982) (8)
Effects of organic solvents on cytochrome c (1969) (7)
The photosynthesis of a 2-methyl-1-pyrroline 1-oxide (1965) (7)
Mechanism of toxicity of 2,2,2-trifluoroethanol in rats. (1986) (7)
Metabolism of monochlorobiphenyls by hepatic microsomal cytochrome P-450. (1980) (7)
Fluroxene (2, 2, 2 ‐ Trifluoroethyl Vinyl Ether) Toxicity: A Chemical Aspect (1976) (7)
A thermodynamic comparison of some oxidations of ferrocytochrome C (1971) (6)
REGULATION OF CYTOCHROME P 4501 A 1 EXPRESSION IN RAT SMALL INTESTINE (1997) (6)
Multiple aspects of the toxicity of fluroxene and its metabolite 2,2,2-trifluoroethanol. (1988) (6)
2,2,2-Trifluoroethanol-Induced Enteropathy in Rats: Chemically or Bacterially Mediated Effects (1987) (5)
Nitrones. Part VIII. The ultraviolet absorption of the 1-pyrroline 1-oxides (1968) (5)
The role of environmental matrices and experimental vehicles in chlorinated dibenzodioxin and dibenzofuran toxicity (1985) (5)
Fluorescence probing of the function-specific cysteines of rat microsomal NADPH-cytochrome P-450 reductase. (1986) (5)
Molecular orbital studies of the metabolism of fluroxene and analogous fluorinated ether anesthetics. (1981) (5)
Development of the hepatic mixed-function oxidase system and its metabolism of warfarin in the perinatal rat. (1981) (4)
Applications of theoretical chemistry in the prediction of metabolism (1983) (4)
An investigation into the hepatic cytochrome P-450 catalysed metabolism of the anaesthetic fluroxene (2,2,2-trifluoroethyl vinyl ether). (1975) (4)
Thermodynamic aspects of cytochrome c function. (1971) (3)
An Intestinal Epithelium-Specific Cytochrome P450 Reductase-Knockout Mouse Model: Direct Evidence for A Role of Intestinal Cytochromes P450 in First-pass Clearance of Oral Nifedipine (2008) (3)
A reversal of heme crevice strengths of ferri- and ferrocytochrome c on carboxymethylation. (1972) (3)
Nitrones. Part V. The reaction of a cyclic nitrone with diethyl malonate (1967) (3)
The ascorbate reduction of denatured ferricytochrome c. (1972) (3)
Cytochrome P450 mRNA induction: quantitation by RNA-polymerase chain reaction using capillary electrophoresis. (1996) (3)
The reactivity of conformationally modified cytochrome c. (1974) (2)
Toxicology of atmospheric degradation products of selected hydrochlorofluorocarbons (1990) (2)
2,2,2-Trifluoroethanol Toxicity in Aged Rats (1988) (2)
DIFFERENCES IN THE INTERACTIONS OF R AND S WARFARIN WITH HEPATIC MICROSOMAL CYTOCHROME P-450 (1977) (2)
Synthesis of four tritium‐labelled aminowarfarin methyl ketal regioisomers (1992) (2)
The emulsifying properties of egg yolk phosphatidylcholine (1972) (2)
Fluoride: benefits and risks of exposure. The preparation of a report. (1992) (2)
METABOLISM OF FLUROXENE AND ANALOGOUS FLUORINATED ETHER ANESTHETICS BY HIGHLY PURIFIED CYTOCHROMES P-450 AND THE ASSOCIATED ENZYME DESTRUCTION (1980) (1)
2,2,2-Trifluoroethanol Toxicity in Hamsters (Mesocricetus auratus) (1987) (1)
WARFARIN METABOLISM - A PROBE OF PURIFIED RAT LIVER CYTOCHROMES P-450 (1980) (1)
8 – Chemical Alterations of Volatile Anesthetic Agent-Induced Hepato- and Nephrotoxicity (1990) (1)
Cytochrome P450: Probes of Active Site Residues (1993) (0)
FURTHER STUDIES OF THE FLUROXENE MEDIATED DESTRUCTION OF HEPATIC MICROSOMAL CYTOCHROMES P-450 IN VITRO (1977) (0)
A NEW WARFARIN METABOLITE- STRUCTURE AND FUNCTION (1979) (0)
THE DEVELOPMENT OF HEPATIC MIXED-FUNCTION OXIDASES - WARFARIN METABOLISM AS A PROBE (1980) (0)
The autoxidation of cytochrome c: alcohols as possible models for the hydrophobic mitochondrial environment. (1971) (0)
XII. BIOLOGICAL AND HEALTH EFFECTS (2012) (0)
Substrate specificities and stereoselectivities of 7 purified isozymes of rat liver cytochrome p 450 (1982) (0)
Activation of DNA Damage Signaling Components by Diagnostic Computed Tomography (CT) Scans Detected in Patient Samples Using an Electrochemiluminescence-Based Assay Platform (2017) (0)
Selective inhibition by chloramphenicol of pregnenolone-16. cap alpha. -carbonitrile-inducible rat liver cytochrome P-450 isozymes (1986) (0)
Azidowarfarin as photoaffinity probe of cytochromes P450. (1991) (0)
1495 – POTENTIATION OF FLUROXENE TOXICITY BY POLYCHLORINATED BIPHENYL INDUCED CYTOCHROME P-450 (1978) (0)

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What Schools Are Affiliated With Lawrence S. Kaminsky?

Lawrence S. Kaminsky is affiliated with the following schools:

University at Albany, SUNY

Lawrence S. Kaminsky's Academic­Influence.com Rankings

Why Is Lawrence S. Kaminsky Influential?

Lawrence S. Kaminsky's Published Works

Published Works

What Schools Are Affiliated With Lawrence S. Kaminsky?

Lawrence S. Kaminsky's AcademicInfluence.com Rankings