Leonhard S. Wolfe
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Leonhard S. Wolfeengineering Degrees
Engineering
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Electrical Engineering
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Engineering
Why Is Leonhard S. Wolfe Influential?
(Suggest an Edit or Addition)Leonhard S. Wolfe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Arachidonic Acid Cascade and Signal Transduction (1990) (583)
- Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon‐20 Unsaturated Fatty Acids (1982) (561)
- Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease). (1992) (363)
- Isolation of plasma membranes from rat brain. (1971) (300)
- Progressive myoclonus epilepsies: specific causes and diagnosis. (1986) (295)
- The role of prostaglandins in the central nervous system. (1979) (238)
- Kufs' disease: a critical reappraisal. (1988) (210)
- Inhibition of prostaglandin synthesis by oleic, linoleic and linolenic acids. (1968) (189)
- Effect of nerve stimulation on prostaglandin formation and release from the rat stomach. (1967) (186)
- Gangliosides in Isolated Neurons and Glial Cells (1967) (165)
- Experimental vasoconstriction of cerebral arteries by prostaglandins. (1972) (145)
- A novel prostaglandin derivative formed from arachidonic acid by rat stomach homogenates. (1971) (144)
- High Levels of Brain Dolichols in Neuronal Ceroid‐Lipofuscinosis and Senescence (1983) (135)
- Endogenous formation of the prostaglandin endoperoxide metabolite, thromboxane B2, by brain tissue. (1976) (121)
- Specific storage of subunit c of mitochondrial ATP synthase in lysosomes of neuronal ceroid lipofuscinosis (Batten's disease). (1992) (119)
- The endogenous biosynthesis of prostaglandins by brain tissue in vitro. (1976) (115)
- Late infantile systemic lipidosis Major monosialogangliosidosis Delineation of two types (1968) (106)
- Lysosomal storage of the DCCD reactive proteolipid subunit of mitochondrial ATP synthase in human and ovine ceroid lipofuscinoses. (1989) (103)
- GM1‐gangliosidosis without chondrodystrophy or visceromegaly (1970) (101)
- Biosynthesis of Prostacyclin in Rat Cerebral Microvessels and the Choroid Plexus (1981) (98)
- Origin of the arachidonic acid released post-mortem in rat forebrain. (1979) (98)
- Dolichols in brain and urinary sediment in neuronad ceroid lipofuscinosis (1983) (94)
- Identification of retinoyl complexes as the autofluorescent component of the neuronal storage material in Batten disease (1977) (89)
- Lipofuscin: characteristics and significance. (1986) (88)
- On the action of prostaglandin E1 and prostaglandins from brain on the isolated rat stomach. (1966) (88)
- Measurement of prostaglandin F2α levels in human cerebrospinal fluid in normal and pathological conditions (1975) (82)
- Gangliosides in developing rat brain. Isolation and composition of subcellular membranes enriched in gangliosides. (1967) (81)
- The structures of oligosaccharides accumulating in the liver of G-M1-gangliosidosis, type I. (1974) (80)
- Ceramide trihexosidosis (fabry's disease) without skin lesions. (1971) (77)
- STUDIES ON BRAIN GANGLIOSIDES. 3. EVIDENCE FOR THE LOCATION OF GANGLIOSIDES SPECIFICALLY IN NEURONES. (1964) (75)
- Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. (1978) (72)
- PROSTAGLANDINS IN BRAIN AND THE RELEASE OF PROSTAGLANDIN-LIKE COMPOUNDS FROM THE CAT CEREBELLAR CORTEX. (1965) (71)
- Effects of Indomethacin and Ibuprofen on Cerebral Metabolism and Blood Flow in Traumatized Brain (1983) (71)
- The biosynthesis of prostaglandins by brain tissue in vitro. (1976) (67)
- Specific Delay of Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis (Batten Disease) (1995) (67)
- Enzyme replacement therapy by renal allotransplantation in Fabry's disease. (1972) (64)
- Possible Roles of Prostaglandins in the Nervous System (1975) (64)
- GM1 gangliosidosis in skin fibroblast culture: enzymatic differences between types 1 and 2 and observations on a third variant. (1974) (61)
- Biosynthesis of prostaglandins E2 and F2-alpha from tritium-labelled arachidonic acid by rat stomach homogenates. (1970) (60)
- Long-term changes of synaptic transmission induced by arachidonic acid in the CA1 subfield of the rat hippocampus (1990) (59)
- A type of juvenile cerebromacular degeneration characterized by granular osmiophilic deposits. (1973) (58)
- Hermansky-Pudlak syndrome in a Swiss population. (1993) (57)
- N-butylboronate derivatives of the F prostaglandins. Resolution of prostaglandins of the E and F series by gas-liquid chromatography. (1971) (56)
- Genetic variants of Tay-Sachs disease: Tay-Sachs disease and Sandhoff's disease in French Canadians, juvenile Tay-Sachs disease in Lebanese Canadians, and a Tay-Sachs screening program in the French-Canadian population. (1977) (55)
- RAISED LEVELS OF CEREBRAL CORTEX DOLICHOLS IN ALZHEIMER'S DISEASE (1982) (53)
- Urinary sediment dolichols in the diagnosis of neuronal ceroid‐lipofuscinosis (1986) (51)
- THE EFFECT OF VINCRISTINE ON SKELETAL MUSCLE IN THE RAT: A Correlative Histochemical, Ultrastructural and Chemical Study (1972) (49)
- Extracellular matrix regulates proliferation and phospholipid turnover in glomerular epithelial cells. (1990) (45)
- Juvenile progressive dystonia: A new phenotype of GM2 Gangliosidosis (1984) (44)
- Elevated urinary dolichol excretion in the Hermansky-Pudlak syndrome. Indicator of lysosomal dysfunction. (1987) (42)
- Evidence for a terminal -D-galactopyranosyl residue in galactosylgalactosylglucosylceramide from human kidney. (1971) (40)
- Hexosaminidase-A deficiency presenting as atypical juvenile-onset spinal muscular atrophy. (1985) (39)
- Oligosaccharides accumulating in the liver from a patient with GM2-gangliosidosis variant O (Sandhoff-Jatzkewitz disease). (1974) (39)
- Infantile sialidosis: a phenocopy of type 1 GM1 gangliosidosis distinguished by genetic complementation and urinary oligosaccharides. (1979) (39)
- Juvenile dystonic lipidosis (1977) (39)
- EFFECT OF ALPHA‐PARTICLE IRRADIATION ON BRAIN GLYCOGEN IN THE RAT (1962) (38)
- Action myoclonus-renal failure syndrome: a previously unrecognized neurological disorder unmasked by advances in nephrology. (1986) (38)
- Adult onset motor neuronopathy in the juvenile type of hexosaminidase A and B deficiency (1988) (37)
- Abnormal degradative pathway of mitochondrial ATP synthase subunit c in late infantile neuronal ceroid-lipofuscinosis (Batten disease). (1995) (36)
- Specific Delay in the Degradation of Mitochondrial ATP Synthase Subunit c in Late Infantile Neuronal Ceroid Lipofuscinosis Is Derived from Cellular Proteolytic Dysfunction Rather than Structural Alteration of Subunit c (1996) (36)
- Presence of Abnormal Amounts of Dolichols in the Urinary Sediment of Batten Disease Patients (1982) (34)
- Preparation of radiolabeled GM2 and GA2 gangliosides. (1979) (34)
- Diagnostic value of kidney biopsy in heterozygous Fabry's disease. (1985) (34)
- Virus‐like filaments and phospholipid accumulation in skeletal muscle (1970) (34)
- Some Further Studies on Vasogenic Edema (1976) (33)
- Isolation and characterization of keratan sulfates from the liver of a patient with GM1-gangliosidosis type I. (1970) (32)
- High-performance liquid chromatographic analysis of oligosaccharides and glycopeptides accumulating in lysosomal storage disorders. (1980) (31)
- Kufs disease: clinical features and forms. (1988) (31)
- A peculiar polysaccharide accumulation in muscle in a case of cardioskeletal myopathy (1969) (30)
- Infantile neuronal ceroid lipofuscinosis (1982) (30)
- Release of arachidonic acid by NMDA-receptor activation in the rat hippocampus (1991) (29)
- Therapeutic abortion with the use of prostaglandin F2α (1972) (28)
- Characterization of oligosaccharides and glycopeptides excreted in the urine of GMl-gangliosidosis patients. (1975) (25)
- Metabolism of prostaglandin F1α by the rat stomach (1970) (25)
- Arachidonic Acid Metabolites in the Rat and Human Brain New Findings on the Metabolism of Prostaglandin D2 and Lipoxygenase Products a (1989) (25)
- CELL MEMBRANE CONSTITUENTS CONCERNED WITH TRANSPORT MECHANISMS. (1964) (24)
- Effect of Drugs on Local Cerebral Glucose Utilization in Traumatized Brain: Mechanisms of Action of Steroids Revisited (1984) (23)
- The Newfoundland aggregate of neuronal ceroid-lipofuscinosis. (1988) (22)
- Dolichol and dolichyl phosphate in the neuronal ceroid-lipofuscinoses and other diseases. (1988) (21)
- Effect of Hypoxia on Brain Gangliosides (1963) (20)
- STUDIES ON BRAIN GANGLIOSIDES. I. THE ISOLATION AND COMPOSITION OF A TRISIALOGANGLIOSIDE. (1964) (20)
- Sanfilippo syndrome type D. (1987) (20)
- Multiple peripheral nerve entrapments. An unusual phenotypical variant of the Hunter syndrome (mucopolysaccharidosis II) in a family. (1974) (20)
- STUDIES ON BRAIN GANGLIOSIDES. IV. THE EFFECT OF HYPERCAPNIA ON GANGLIOSIDES IN VIVO. (1964) (19)
- Phosphatidylcholine and 4-methylumbelliferyl phosphorylcholine hydrolysis by purified placental sphingomyelinase. (1985) (19)
- THE EFFECT OF CATIONS ON THE EXTRACTABILITY OF GANGLIOSIDES FROM BRAIN (1967) (19)
- Functional disturbances in brain following injury (2004) (19)
- G M1 -gangliosidosis (Type II): studies on a fibroblast cell strain. (1970) (19)
- Involvement of arachidonic acid metabolites in experimental brain injury. Identification of lipoxygenase products in brain. Clinical studies on prostacyclin infusion in acute cerebral ischemia. (1985) (17)
- Methods for Separation and Determination of Gangliosides (1972) (15)
- The effect of dolichol phosphate on the synthesis of lipid bound sugars in embryonic chick brain (1973) (15)
- Metabolism of Prostaglandin D2 by Human Cerebral Cortex into 9α, 11β‐Prostaglandin F2 by an Active NADPH‐Dependent 11‐Ketoreductase (1989) (14)
- THE STRUCTURE OF BRAIN POLYISOPRENOLS 1 (1973) (14)
- Effect of PGF2alpha and 15(S)-15-methyl-PGE2 methyl ester on feline generalized penicillin epilepsy. (1975) (14)
- Dolichols are elevated in brain tissue from Alzheimer's disease, but not in urinary sediment from Alzheimer's disease and Down's syndrome. (1985) (14)
- Urticaria due to drugs of the digitalis series. (1953) (12)
- Evidence for the use of a pool of the free arachidonic acid in rat cerebral cortex tissue for prostaglandin F2alpha synthesis in vitro. (1979) (12)
- Decreased lysosomal subunit c-degrading activity in fibroblasts from patients with late infantile neuronal ceroid lipofuscinosis. (1997) (12)
- Formation of 12-lipoxygenase metabolites in rat cerebral cortical slices: stimulation by calcium ionophore, glutamate and N-methyl-D-aspartate. (1990) (12)
- Ca2+ depletion-induced disconnection of tight junctions in isolated rat brain microvessels (2004) (11)
- Disappearance of prostaglandin F2alpha from human amniotic fluid after intraamniotic injection. (1972) (11)
- Urinary excretion of a novel hexasaccharide and glycopeptide analogue in fucosidosis. (1979) (11)
- THE PRODUCTION OF ANTISERA TO GANGLIOSIDES FROM HUMAN NERVOUS TISSUE. (1964) (11)
- STUDIES ON BRAIN GANGLIOSIDES. II. ANALYSIS OF HUMAN BRAIN GANGLIOSIDE FRACTIONS OBTAINED BY PREPARATIVE THIN-LAYER CHROMATOGRAPHY. (1964) (10)
- Polyhydroxylated by-products of the enzymatic conversion of tritiated arachidonic acid into prostaglandins by sheep seminal vesicles (1970) (10)
- Tay-Sachs disease in Quebec: evidence for a geographic aggregate in the French-Canadian population and identification of a new retardation syndrome with possible linkage to the Tay-Sachs gene. (1973) (9)
- INVOLVEMENT OF MANNOSYL‐PHOSPHORYL‐DOLICHOLS IN MANNOSE TRANSFER TO BRAIN GLYCOPROTEINS (1974) (9)
- Structure of the minor oligosaccharides in the liver of a patient with GM2-gangliosidosis variant O (Sandhoff-Jatzkewitz disease). (1978) (8)
- Ganglioside analyses of serial cryostat sections through Ammon's horn and cerebellar folia (2004) (7)
- Defect of proteolysis of mitochondrial ATP synthase subunit C in neuronal ceroid lipofuscinosis. (1995) (7)
- Effects of prostaglandins on cerebral blood flow. (1971) (7)
- Retinoyl Complexes in Batten Disease (1977) (7)
- Glutamate induces 12 hete synthesis through nmda receptor activation in rat cerebral cortex (1988) (7)
- Biochemical Studies on GM1-Gangliosidosis and Ceramide Trihexosidosis (1972) (7)
- ENZYME MANIPULATION: EVALUATION OF ORAL ZnSO4 SUP-PLEMENTATION IN MANNOSIDOSIS TYPE II (1977) (6)
- Brain hepoxilins: formation and action. (1989) (6)
- Neurochemical Sequelae of Brain Damage and Their Role in Functional Disturbances (1986) (6)
- The hydrolysis of p-acetoxyphenylethylamines by insect cholinesterase. (1958) (6)
- Synthesis and functions of cyclooxygenase and lipoxygenase products in brain: new findings and an appraisal. (1989) (6)
- New insight into lysosomal protein storage disease: Delayed catabolism of ATP synthase subunit c in batten disease (1995) (5)
- STUDIES ON THE METABOLIC EFFECTS OF A SUBSTANCE FOUND IN PERIPHERAL NERVE (1962) (5)
- Measurement of prostaglandin F2alpha levels in human cerebrospinal fluid in normal and pathological conditions. (1975) (5)
- Cerebromacular Degeneration: Progress and prospects in the search for the elusive biochemical defect (1979) (4)
- Letter: Shuddering attacks in children: essential tremor and monosodium glutamate. (1976) (4)
- Storage and excretion of oligosaccharides and glycopeptides in the gangliosidoses. (1976) (3)
- Batten disease: new research findings on the biochemical defect. (1982) (3)
- Lipid-protein complexes in membranes of nervous tissue. (1962) (3)
- The biosynthesis of prostaglandins and thromboxanes by nervous tissue. (1977) (3)
- Virus like filaments and phospholipid accumulations in a case of chronic myopathy. (1971) (3)
- A prostanoic acid derivative formed in the enzymatic conversion of tritiated arachidonic acid into prostaglandins by rat stomach homogenates (1970) (3)
- Therapeutic abortion in the second trimester by intra-amniotic prostaglandin F2 alpha . (1972) (3)
- Induction of abortion by intraamniotic PGF2alpha: a comparison of dose schedules. (1973) (3)
- Involvement of arachidonic acid metabolites in functional disturbances following brain injury. (1983) (2)
- Effect of PGF2 alpha and 15(S)-15-methyl PGE2 methyl ester on feline generalized penicillin epilepsy. (1975) (2)
- Lysosomal Proteinosis Based on Decreased Degration of a Specific Protein, Mitochondrial ATP Synthase Subunit C (1996) (2)
- Some facts and thoughts on the biosynthesis of prostaglandins and thromboxanes in brain. (1978) (2)
- Molecular basis of lysosomal accumulation of subunit c of mitochondrial ATP synthase in neuronal ceroid-lipofuscinosis (1993) (2)
- Therapeutic abortion with the use of prostaglandin F 2 . A study of efficacy, tolerance, and plasma levels with intravenous administration. (1972) (2)
- List of Key Words (1995) (1)
- Lysosomal proteinosis based on decreased degradation of a specific protein, mitochondrial ATP synthase subunit C: Batten disease. (1996) (1)
- Expression of GM1-gangliosidosis Types I and II in Fibroblast Cell Culture (1970) (1)
- Biologically Active Lipids (1970) (1)
- Structure of oligo saccharides accumulating in the liver of g m1 gangliosidosis type i (1973) (0)
- Infantile neuroaxonal dystrophy with urinary oligosaccharide excretion not due to defective α-N- acetylgalactosaminidase activity (1994) (0)
- Farm glossary : definitions of words and phrases usually encountered in reading literature dealing with agriculture and its allied sciences (1948) (0)
- Theodore Lionel Sourkes: an appreciation (1990) (0)
- Contents, Vol. 6, 1971 / Foreword (1971) (0)
- Skin Fibroblast Culture: Enzymatic Differences between Types 1 and 2 and Observations (2006) (0)
- Chemical studies on brain gangliosides in normal and pathological states. (1964) (0)
- THE CURVILINEAR BODIES OF LATE INFANTILE BATTENʼS DISEASE-ISOLATION AND CHEMICAL AND ULTRASTRUCTURAL CHARACTERIZATION: 90 (1976) (0)
- Metabolism of prostaglandin D2 by human cerebral cortex into 9 alpha, 11 beta-prostaglandin F2 by an active NADPH-dependent 11-ketoreductase. (1989) (0)
- Introductory comments (1989) (0)
- Familial Adult-onset Motor Neuronopathy Due to a β-Locus Hexosaminidase Mutation (1987) (0)
- Experimental vincristine myopathy--a histochemical, ultrastructural and biochemical study. (1971) (0)
- Diseases of the Homeless (1985) (0)
- Contents, Vol. 187, 1993 (1993) (0)
- Book Review:Prostaglandins and the Cardiovascular System. John A. Oates, Bengt Samuelson, Rodolfo Paoletti (1984) (0)
- NITRIC OXIDE IN HEALTH AND DISEASE. 1997. Edited by: Jill Lincoln, Charles H.V. Hoyle and Geoffrey Burnstock. Published by Cambridge University Press. 363 pages. $C51.94 approx. (1998) (0)
- Inhibition and Reversal of Prostaglandin-Induced Cerebral Vasospasm (1975) (0)
- GANGLIOSIDE ANALYSES OF SERIAL SECTIONS THROUGH BRAIN REGIONS AND OF ISOLATED NEURONES (1969) (0)
- Prostaglandin research. (1977) (0)
- [Prostaglandin presence in and liberation by the rat stomach]. (1967) (0)
- Title Page / Table of Contents, Supplement 2, 1995 (1995) (0)
- THE ISOLATION AND COMPOSITION OF A GANGLIOSIDE-RICH MEMBRANE FRACTION FROM NEW-BORN RAT BRAIN (1966) (0)
- In Memoriam: Kenneth Allan Caldwell Elliott 1903–1986 (1986) (0)
- 5.5 – PROSTAGLANDINS (1971) (0)
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