Leon w. Hoyer
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Leon w. Hoyerphilosophy Degrees
Philosophy
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#13088
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Logic
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#8010
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Leon w. Hoyerbiology Degrees
Biology
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Cell Biology
#714
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#729
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Molecular Biology
#2168
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#2202
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Biochemistry
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#2406
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Philosophy Biology
Leon w. Hoyer's Degrees
- PhD Biochemistry University of California, Berkeley
- Doctorate Medicine Stanford University
Why Is Leon w. Hoyer Influential?
(Suggest an Edit or Addition)Leon w. Hoyer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Synthesis of antihemophilic factor antigen by cultured human endothelial cells. (1973) (1250)
- Synthesis of von Willebrand factor by cultured human endothelial cells. (1974) (468)
- Quantitative assay of a plasma factor deficient in von Willebrand's disease that is necessary for platelet aggregation. Relationship to factor VIII procoagulant activity and antigen content. (1973) (424)
- Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease. (1977) (423)
- Antihemophilic factor antigen. Localization in endothelial cells by immunofluorescent microscopy. (1973) (422)
- The factor VIII complex: structure and function. (1981) (239)
- Determination of the von Willebrand's disease antigen (factor VIII-related antigen) in plasma by quantitative immunoelectrophoresis. (1975) (201)
- The factor VIII complex: structure and function. (1981) (198)
- Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid. (1989) (182)
- Immunologic studies of antihemophilic factor (AHF, factor VIII). IV. Radioimmunoassay of AHF antigen. (1972) (180)
- Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene. (1991) (173)
- Response of patients with mild and moderate hemophilia A and von Willebrand's disease to treatment with desmopressin. (1985) (161)
- Immunoradiometric measurement of the factor VIII procoagulant antigen. (1978) (156)
- Inactivation of factor VIII coagulant activity by two different types of human antibodies. (1982) (155)
- Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene, second edition. (1994) (150)
- Moderation of hemophilia A phenotype by the factor V R506Q mutation. (1996) (145)
- Von Willebrand Factor: Dissociation from Antihemophilic Factor Procoagulant Activity (1973) (141)
- Transgenic pigs produce functional human factor VIII in milk (1997) (137)
- Inhibitor Antibody Development and T Cell Response to Human Factor VIII in Murine Hemophilia A (1999) (137)
- Residues 484-508 Contain a Major Determinant of the Inhibitory Epitope in the A2 Domain of Human Factor VIII (*) (1995) (136)
- Tissue factor activity in lymphocyte cultures from normal individuals and patients with hemophilia A. (1973) (107)
- Immunologic studies of antihemophilic factor (AHF, factor VIII). V. Immunologic properties of AHF subunits produced by salt dissociation. (1973) (106)
- Partial correction of a severe molecular defect in hemophilia A, because of errors during expression of the factor VIII gene. (1997) (104)
- Von Willebrand factor multimer patterns in von Willebrand's disease (1983) (91)
- The effect of thrombin on human factor VIII. Cleavage of the factor VIII procoagulant protein during activation. (1981) (90)
- Mechanism of the Immune Response to Human Factor VIII in Murine Hemophilia A (2001) (88)
- The incidence of factor VIII inhibitors in patients with severe hemophilia A. (1995) (79)
- Factor VIII inhibitors: structure and function in autoantibody and hemophilia A patients. (1994) (79)
- Role of CD154 in the secondary immune response: the reduction of pre‐existing splenic germinal centers and anti‐factor VIII inhibitor titer (2000) (77)
- Direct characterization of factor VIII in plasma: detection of a mutation altering a thrombin cleavage site (arginine-372----histidine). (1989) (76)
- Synthesis and Release of Factor VIII by Cultured Human Endothelial Cells (1981) (72)
- von Willebrand factor abnormalities in primary pulmonary hypertension. (1987) (66)
- The effects of epinephrine infusion in patients with von Willebrand's disease. (1976) (66)
- Immunochemical characterization of factor VIII inhibitors. (1984) (65)
- The properties of factor VIII coagulant activity prepared by immunoadsorbent chromatography. (1979) (59)
- von Willebrand's disease and hemorrhagic telangiectasia: association of two complex disorders of hemostasis resulting in life-threatening hemorrhage. (1977) (58)
- Immunofluorescent localization of antihemophilic factor antigen and fibrinogen in human renal diseases. (1974) (55)
- Spectrum of mutations in CRM-positive and CRM-reduced hemophilia A. (1993) (53)
- A Soluble Recombinant Factor VIII Fragment Containing the A2 Domain Binds to Some Human Anti-Factor VIII Antibodies that Are not Detected by Immunoblotting (1992) (52)
- WHY DO SO MANY HAEMOPHILIA A PATIENTS DEVELOP AN INHIBITOR? (1995) (49)
- Hemophilia A due to mutations that create new N-glycosylation sites. (1992) (48)
- Standard Nomenclature for Factor VIII and von Willebrand Factor: A Recommendation by the International Committee on Thrombosis and Haemostasis (1985) (45)
- The significance of erythrocyte antigen site density. I. Hemagglutination. (1970) (42)
- STUDIES ON POSTTRANSFUSION AND DISSOCIATED FACTOR VIII AND IN PATIENTS WITH VON WILLEBRAND'S DISEASE (1977) (41)
- The effect of 1‐deamino 8 D‐arginine vasopressin (DDAVP) in a nonhaemophilic patient with an acquired type II factor VIII inhibitor (1985) (39)
- EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: THE EFFECT OF 6-MERCAPTOPURINE (1962) (37)
- Thrombin Activation of Factor VIII: the Effect of Inhibitors (1977) (36)
- THE EFFECT OF 6-MERCAPTOPURINE ON DELAYED HYPERSENSITIVITY IN GUINEA PIGS (1962) (36)
- Histocompatibility antigen patterns in haemophilic patients with factor VIII antibodies (1990) (36)
- Characterization of a thrombin cleavage site mutation (Arg 1689 to Cys) in the factor VIII gene of two unrelated patients with cross-reacting material-positive hemophilia A. (1990) (35)
- Molecular pathology and immunology of factor VIII (hemophilia A and factor VIII inhibitors). (1987) (35)
- Amegakaryocytic thrombocytopenia in systemic lupus erythematosus. (1970) (32)
- The properties of immune complexes formed by human antibodies to factor VIII. (1977) (29)
- Inhibitors to Coagulation Factors (1995) (29)
- Activation of low molecular weight fragment of antihaemophilic factor (factor VIII) by thrombin (1974) (28)
- von Willebrand factor and platelet function. (1986) (28)
- Nomenclature of Quantities and Units in Thrombosis and Haemostasis (Recommendation 1993) (1994) (26)
- Multicenter Comparison of von Willebrand Factor Multimer Sizing Techniques (1985) (26)
- HETEROGENEITY OF RABBIT IGM ANTIBODY AS DETECTED BY C'1a FIXATION (1968) (26)
- Molecular weight of human factor VIII procoagulant activity. (1975) (25)
- Prevention of Experimental Allergic Encephalomyelitis with 6-Mercaptopurine.∗ (1960) (23)
- Factor VIII coagulant antigen in factor IX complex concentrates. (1979) (23)
- Thrombin Activation of Factor VIII (1978) (22)
- Factor VIII inhibitors (1995) (22)
- The significance of erythrocyte antigen site density. II. Hemolysis. (1971) (20)
- The idiotypic characteristics of human antibodies to factor VIII. (1984) (19)
- Coagulation Activities in Perfused Organs: Regulation by Addition of Animal Plasmas (1974) (19)
- Specificity of precipitating antibodies in immunological identification of antihaemophilic factor. (1973) (17)
- Mild hemophilia A associated with a cryptic donor splice site mutation in intron 4 of the factor VIII gene. (1988) (17)
- Immunologic studies of antihemophilic factor (AHF, VIII:C). VI. Characterization of antigenic determinants using human antibodies. (1982) (16)
- Cultured endothelial cells derived from the human iliac arteries (1982) (14)
- Factor VIII-East Hartford (arginine 1689 to cysteine) has procoagulant activity when separated from von Willebrand factor. (1992) (13)
- IMPLICATIONS OF IMMUNOLOGIC METHODS FOR MEASURING ANTIHEMOPHILIC FACTOR (FACTOR VIII) * (1975) (13)
- Immunoradiometric assays for factor VIII antigens: coagulant protein (antihemophilic factor) and factor VIII-related protein (von Willebrand factor). (1982) (12)
- The Factor VIII Complex (1982) (11)
- Cysteamine enhances the procoagulant activity of Factor VIII-East Hartford, a dysfunctional protein due to a light chain thrombin cleavage site mutation (arginine-1689 to cysteine). (1992) (11)
- Future approaches to factor VIII inhibitor therapy. (1991) (10)
- Antibody elution from hapten-cellulose immunoadsorbents: the effects of hapten structure, pH and salt concentration. (1968) (10)
- Characterization of the immune response to factor VIII using hemophilia A* mice. (2000) (9)
- Hemophilia A in a female: use of factor 8 antigen levels as a diagnostic aid. (1974) (9)
- Recombinant Technology in Hemostasis and Thrombosis (2012) (9)
- Allelic light chain allotype distribution in purified IgG and IgM rabbit antibodies. (1967) (9)
- The dental management of patients with spontaneous acquired factor VIII inhibitors. (1986) (8)
- Report of the Subcommittee on Factor VIII Activities (1980) (7)
- AND PLATELET FUNCTION (1986) (6)
- Immunologic properties of antihemophilic factor. (1973) (6)
- Characterization of dysfunctional factor VIII molecules. (1993) (5)
- PRODUCTION OF HUMAN THERAPEUTIC PROTEINS IN TRANSGENIC ANIMALS (1994) (5)
- Factor VIII inhibitors: a continuing problem. (1993) (5)
- Molecular Biology of Factor VIII/von Willebrand Factor (1978) (4)
- Immunofluorescent localization of factor VIII-related antigen and fibrinogen in hyperacute xenograft rejection and in the Shwartzman reaction in the rat. (1978) (4)
- Rabbit factor VIII: identification of size heterogeneity. (1977) (4)
- Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene, second edition. (1994) (4)
- Erratum: Haemophilia A: Database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene, second edition (Nucleic Acids Research (1994) 22 (3511-3533)) (1994) (2)
- Factor VIII: new perspectives. (1987) (2)
- Stabilization of the Antihemophilic Factor (VIII :AHF) by the Von Willebrand Factor (VIII :VWF): A Possible Model for Von Willebrand’s Disease (1977) (2)
- The Critical Role of the Factor VIII/von Willebrand Factor Complex in Hemostasis (1987) (2)
- New alternatives and strategies in the treatment of inhibitors. (1984) (1)
- WHY DO SO MANY HEMOPHILIA A PATIENTS DEVOLOP INHIBITORS (1995) (1)
- The Significance of Erythrocyte Antigen Site Density (2013) (1)
- Molecular Defects in Hemophilia A (1991) (1)
- Factor VIII — structure and function (1982) (1)
- Mixed mononuclear cell cultures do not elaborate factor VIII. (1980) (1)
- Development of an inhibitor specific to factor VIII: coagulant activity in a patient with platelet-type von Willebrand's disease. (1983) (1)
- Response of protein C and protein C inhibitor to warfarin therapy in patient with combined deficiency of Factors V and VIII. (1984) (1)
- Dental treatment for a hemophilia A patient with circulating antibodies to factor VIII. (1978) (1)
- Von Willebrand's disease. (1976) (1)
- In Vitro Studies of Synthesis and Release of Factor VIII Related Protein by Endothelial Cells (1977) (1)
- DDAVP (desmopressin) in the dental management of patients with mild or moderate hemophilia and von Willebrand's disease. (1985) (1)
- Factor VIII subunits. (1975) (0)
- Factor VIII inhibitors. Proceedings of an international symposium held in Farmington, Connecticut, November 3-5, 1983. (1984) (0)
- Immunologic Approach to the Study of Factor VIII (1977) (0)
- CalciumDoes Not Interferewith Measurementof (1987) (0)
- Structure-Function Relationships of Human Coagulation Proteins (1991) (0)
- DISCUSSION PAPER: FACTOR VIII SUBUNITS (1975) (0)
- The Future of Research in Transfusion Medicine: Can We Make Blood Transfusion Safer and More Effective? (1992) (0)
- Panel discussion on the development of inhibitors: Who and why? (1995) (0)
- Factor VilI-East Hartford ( Arginine 1689 to Cysteine ) Has Procoagulant Activity When Separated from von Willebrand Factor (0)
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