Leslie Zieve
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Leslie Zievephilosophy Degrees
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Leslie Zievebiology Degrees
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Philosophy Biology
Leslie Zieve's Degrees
- Doctorate Medicine University of California, San Francisco
- PhD Biochemistry University of California, San Francisco
Why Is Leslie Zieve Influential?
(Suggest an Edit or Addition)Leslie Zieve's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Jaundice, hyperlipemia and hemolytic anemia: a heretofore unrecognized syndrome associated with alcoholic fatty liver and cirrhosis. (1958) (350)
- Synergism between mercaptans and ammonia or fatty acids in the production of coma: a possible role for mercaptans in the pathogenesis of hepatic coma. (1974) (248)
- Mercaptans and dimethyl sulfide in the breath of patients with cirrhosis of the liver. Effect of feeding methionine. (1970) (185)
- Psychomotor performance defects in cirrhotic patients without overt encephalopathy. (1980) (174)
- Zinc deficiency: A complication of Crohn's disease (1980) (169)
- The mechanism of hepatic coma (1981) (144)
- Measurement of lecithinase A in serum and other body fluids. (1961) (125)
- Pathogenesis of hepatic coma. (1966) (123)
- An improved method for the determination of urinary coproporphyrin and an evaluation of factors influencing the analysis. (1951) (113)
- Volatile fatty acids in the breath of patients with cirrhosis of the liver. (1970) (104)
- A rapid and sensitive turbidimetric method for serum lipase based upon differences between the lipases of normal and pancreatitis serum. (1963) (89)
- Synergism between ammonia and fatty acids in the production of coma: implications for hepatic coma. (1974) (89)
- Rapid thin-layer chromatographic separation of phospholipids and neutral lipids of serum. (1962) (79)
- Can hepatic coma be caused by a reduction of brain noradrenaline or dopamine? (1977) (79)
- POST-HEPARIN PHOSPHOLIPASE. (1964) (64)
- The incidence of residuals of viral hepatitis. (1953) (64)
- Shunt encephalomyelopathy. II. Occurrence of permanent myelopathy. (1960) (61)
- Comparative value of serum and urinary amylase in the diagnosis of acute pancreatitis. (1957) (61)
- Blood methanethiol in alcoholic liver disease with and without hepatic encephalopathy. (1980) (57)
- INFLUENCE OF MAGNESIUM DEFICIENCY ON THE UTILIZATION OF THIAMINE (1969) (55)
- Quantitative Estimation of Some Phosphatides and Their Hydrolysis Products by Thin Layer Chromatography. (1963) (53)
- Visual Evoked Potentials in Encephalopathy Induced by Galactosamine, Ammonia, Dimethyldisulfide, and Octanoic Acid (2007) (50)
- A LECITHINASE A IN DUODENAL CONTENTS OF MAN. (1960) (49)
- Pathogenesis of hepatic encephalopathy (1987) (48)
- The effect of lactulose on psychomotor performance tests in alcoholic cirrhotics without overt hepatic encephalopathy. (1984) (46)
- Course of hepatic regeneration after 80% to 90% resection of normal rat liver. Comparison with two-lobe and one-lobe hepatectomy. (1985) (46)
- Zinc deficiency: a complication of Crohn's disease. (1980) (46)
- Aging is associated with reduced liver regeneration and diminished thymidine kinase mRNA content and enzyme activity in the rat. (1991) (44)
- Normal and abnormal variations and clinical significance of the one-minute and total serum bilirubin determinations. (1951) (42)
- Determination of volatile free fatty acids of human blood. (1969) (42)
- Hepatic encephalopathy: summary of present knowledge with an elaboration on recent developments. (1979) (41)
- Conditional deficiencies of ornithine or arginine. (1986) (41)
- Normal limits of urinary coproporphyrin excretion determined by an improved method. (1953) (40)
- Post-heparin phospholipase and post-heparin lipase have different tissue origins. (1972) (37)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. II. Normal limits of eleven representative hepatic tests. (1955) (36)
- Pathogenesis of hepatic coma. (1975) (34)
- Amino acids in liver failure. (1979) (34)
- Encephalopathic effect of phenol in rats. (1983) (33)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. III. Relative effectiveness of hepatic tests in cirrhosis. (1955) (33)
- Acetaminophen liver injury: sequential changes in two biochemical indices of regeneration and their relationship to histologic alterations. (1985) (31)
- Action of methanethiol on membrane (Na+ , K+)-ATPase of rat brain. (1976) (31)
- Reversal of ammonia coma in rats by L-dopa: a peripheral effect. (1979) (31)
- Fat infusions. Toxic effects and alterations in fasting serum lipids following prolonged use. (1961) (30)
- Effect of magnesium deficiency on blood and liver transketolase activity and on the recovery of enzyme activity in thiamine-deficient rats receiving thiamine. (1968) (30)
- Brain methanethiol and ammonia concentrations in experimental hepatic coma and coma induced by injections of various combinations of these substances. (1984) (30)
- CLINICAL VALUE OF DETERMINATIONS OF VARIOUS PANCREATIC ENZYMES IN SERUM. (1964) (29)
- Determination of protein-bound radioiodine with an anion exchange resin. (1956) (28)
- Effect of magnesium deficiency on growth response to thiamine of thiamine-deficient rats. (1968) (28)
- Note on the correlation of initial scores with gains. (1940) (27)
- Peptic ulcer and pulmonary emphysema; their association in hospitalized patients. (1956) (27)
- Hemolytic anemia in liver disease. (1966) (27)
- MISINTERPRETATION AND ABUSE OF LABORATORY TESTS BY CLINICIANS (1966) (27)
- Mechanism of arginine protection against ammonia intoxication in the rat. (1984) (26)
- Secretion of pancreatic enzymes. I. Response to secretin and pancreozymin. (1964) (26)
- Measurement of serum lecithin, lysolecithin, and sphingomyelin by a simplified chromatographic technique. (1962) (25)
- Effect of benzedrine on activity (1937) (24)
- Adenylate energy charge: relation to guanylate energy charge and the adenylate kinase equilibrium constant. (1972) (24)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. I. The utilization of multiple measurements in medicine. (1955) (23)
- Ammonia, octanoate and a mercaptan depress regeneration of normal rat liver after partial hepatectomy (1985) (23)
- An improved method for measuring blood mercaptans. (1977) (22)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. VI. Nature of the interrelationships among hepatic tests in viral hepatitis. (1955) (22)
- Alterations in serum content of pancreatic enzymes. (1962) (21)
- Ammonia toxicity: Comparative protective effect of various arginine and ornithine derivatives, aspartate, benzoate, and carbamyl glutamate (1986) (20)
- Hepatic encephalopathy and orotic aciduria associated with hepatocellular carcinoma in a noncirrhotic liver (1988) (19)
- Aging alters ornithine decarboxylase and decreases polyamines in regenerating rat liver but putrescine replacement has no effect. (1992) (19)
- ACTION OF METHANETHIOL ON Na+, K+‐ATPase: IMPLICATIONS FOR HEPATIC COMA (1974) (18)
- Species difference in pancreatic lipolytic and amylotic enzymes. (1963) (18)
- In vivo studies of GABAergic effects in experimental hepatic encephalopathy (1986) (18)
- Methanethiol and fatty acids depress urea synthesis by the isolated perfused rat liver. (1982) (18)
- Effect of fatty acids on the disposition of ammonia. (1976) (17)
- Relationship between acute pancreatitis and hyperlipemia. (1968) (17)
- TURBIDIMETRIC ASSAY FOR PHOSPHOLIPASE A. (1964) (16)
- Hepatic regenerative enzyme activity after pericentral and periportal lobular toxic injury. (1986) (16)
- Effects of magnesium deficiency on protein and nucleic acid synthesis in vivo. (1977) (16)
- What determines blood ammonia (1979) (16)
- Toxicity of a fatty acid and ammonia: interactions with hypoglycemia and Krebs cycle inhibition. (1983) (16)
- Effect of sorbitol on psychomotor function: its use in alcoholic cirrhosis. (1981) (15)
- Shunt encephalomyelopathy. I. Recurrent protein encephalopathy with response to arginine. (1960) (15)
- Studies of liver function tests. III. Dependence of percentage cholesterol esters upon the degree of jaundice. (1953) (15)
- Intracellular distribution of phosphate in the underfed rat developing weakness and coma following total parenteral nutrition. (1976) (15)
- The exchangeable character of accumulated I131 in the thyroid gland of a goitrous cretin. (1957) (14)
- Conversion of Lecithin to Lysolecithin as a Source of Fatty Acids in Incubated Plasma or Serum (1962) (14)
- Turbidimetric serum phospholipase A activity in acute pancreatitis. (1966) (14)
- Artificial Liver Support (1981) (14)
- Measurement of volatile mercaptans in whole blood. (1973) (14)
- Encephalopathy Due to Short- and Medium-Chain Fatty Acids (1985) (14)
- Clinical value of the plasma butanol-extractable (thyroxine) I131 in the diagnosis of hyperthyroidism and myxedema. (1954) (14)
- Weakness, neuropathy, and coma following total parenteral nutrition in underfed or starved rats: relationship to blood hyperosmolarity and brain water loss. (1978) (14)
- Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat. (1985) (13)
- Hepatic regenerative enzyme activity after diffuse injury with galactosamine: relationship to histologic alterations. (1988) (13)
- Ultrastructural study of hepatic regeneration following one-lobe, two-lobe, and subtotal hepatectomy in the rat. (1990) (12)
- Influence of alcohol consumption on hepatic function in healthy gainfully employed men. (1953) (12)
- Comparative value of the basal metabolic rate, chemical protein-bound iodine, and radioactive iodine excretion or uptake in the diagnosis of borderline hyperthyroidism when used individually or in combination. (1955) (11)
- Hepatic Encephalopathy. Management with Lactulose and Related Carbohydrates. Edited by H. O. Conn and J. Bircher, 363 pp. East Lansing, Michigan: Med‐Ed Press, 1988. $49.00 (1989) (11)
- A benzodiazepine antagonist does not alter the course of hepatic encephalopathy or neural γ-aminobutyric acid (GABA) binding (1987) (11)
- Synergism Among Toxic Factors and Other Endogenous Abnormalities in Hepatic Encephalopathy (1981) (11)
- Descriptive characteristics of group of patients with moderate or severe diabetic acidosis; relation to recovery or death. (1953) (11)
- Alterations in thyroid I-131 uptake, basal metabolic rate and serum cholesterol following treatment of hyperthyroidism with radioactive iodine; value in early prediction of success or failure of therapy. (1956) (10)
- Functional hypoglycemia and peptic ulcer. (1966) (10)
- Urea excretion, galactose elimination, and aminopyrine disappearance during normal liver regeneration after partial hepatectomy. Comparison with other function tests reported. (1984) (10)
- Studies of liver function tests. II. Derivation of a correction allowing use of the bromsulfalein test in jaundiced patients. (1951) (10)
- Studies of liver function tests. I. A combined intravenous bromsulphalein-hippuric acid-galactose test. (1950) (9)
- VITAMIN UNRESPONSIVENESS. PROGRESSION OF CLASSIC SIGNS OF NEUROPATHY AND PELLAGRA DURING THERAPY. (1963) (9)
- Secretion of pancreatic enzymes (1967) (9)
- Diseases of the pancreas (1975) (9)
- Encephalopathy Due to Mercaptans and Phenols (1985) (9)
- Discrimination between obstructive and hepatocellular jaundice by means of the commonly used serum tests. (1957) (9)
- Role of Toxins and Synergism in Hepatic Encephalopathy (1989) (9)
- Role of cofactors in the treatment of malnutrition as examplified by magnesium. (1975) (9)
- Comparison of incineration and chloric acid methods for determination of chemical protein-bound iodine. (1954) (8)
- Weight loss after gastrectomy: comparative importance of residual pouch capacity, presence of an innervated pylorus, far excretion, and postoperative symptoms. (1960) (8)
- Inhibition of increases in ornithine decarboxylase and putrescine has no effect on rat liver regeneration. (1992) (8)
- Defective intellectual functionin alcohol ic cirrhotics and nonc irrhotic alcoholics: Relationship to severity of liver disease (1978) (8)
- Phthalate interference in gas-chromatographic determination of long-chain fatty acids in plasma. (1979) (8)
- Effect of carbohydrate load by intravenous infusion in fasted rats on liver glucose-6-phosphate dehydrogenase and malic enzyme. (1974) (8)
- Effects of methanethiol on erythrocyte membrane stabilization and on Na+,K+-adenosine triphosphatase: relevance to hepatic coma. (1984) (8)
- Carotene absorption. A screening test for steatorrhea. (1972) (8)
- Decreased cerebral Uptake of oxygen in coma—a consequence of decreased utilization of ATP (1973) (7)
- JAUNDICE IN CIRRHOSIS. (1965) (6)
- Blood mercaptan and ammonia concentrations in cirrhotics after a protein load. (1978) (6)
- Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat. (1989) (6)
- Studies of liver function tests. IV. Effect of repeated injections of sodium benzoate on the formation of hippuric acid in patients with liver disease. (1953) (6)
- Secretion of pancreatic enzymes (1966) (6)
- Hemolytic Anemia in Cirrhosis (1959) (6)
- Similarities between Postheparin Lipase and Postheparin Phospholipase (1968) (6)
- Alterations in volatile free fatty acids of blood after hepatectomy. (1976) (6)
- Alterations in serum content of pancreatic enzymes. (1962) (5)
- Advances in hepatic encephalopathy and urea cycle diseases (1985) (5)
- Carbamoyl-phosphate synthetase I activity and ureagenesis in regenerating liver of the normal rat. (1985) (5)
- Simplification in the measurement of total fecal fat. (1961) (5)
- The dietary prevention of hepatic coma in eck fistula dogs: Ammonia and the carbohydrate to protein ratio (1987) (5)
- Effects of partial and sham hepatectomy on ornithine decarboxylase and thymidine kinase activities and mRNA contents. (1990) (5)
- Regenerative enzyme activity of the liver after partial hepatectomy or toxic injury depressed by continuous NH4+ infusion. (1989) (4)
- Postsynaptic γ-aminobutyric acid receptors in hepatic coma following portacaval shunt and hepatic artery ligation in the rat (1987) (4)
- Prognosis in moderate or severe diabetic acidosis; effectiveness of various measurements and a derived severity score in predicting the outcome. (1953) (4)
- Two Varieties of Hemolytic Anemia in Cirrhosis (1961) (4)
- Effect of total hepatectomy on selected cerebral substrates and enzymes of the glycolytic pathways and Krebs cycle. (1975) (4)
- Mercaptans in portal systemic encephalopathy (PSE) due to alcoholic liver disease (1978) (4)
- Role of Synergism in the Pathogenesis of Hepatic Encephalopathy (1984) (4)
- Hepatic failure toxins depress liver regenerative enzymes after periportal injury with allyl alcohol in the rat. (1988) (4)
- Relationships between clinical severity of hyperthyroidism and results of thyroid function tests. (1958) (4)
- Duodenal intubation by an improved technique. (1963) (3)
- Secretion of pancreatic enzymes (1966) (3)
- Laboratory notes: Urine Amylase (1961) (3)
- Separation of 32P-labeled inorganic phosphate from rat liver homogenates. (1977) (3)
- Effect of surface-active agents on post-heparin lipase activity. (1968) (3)
- An Improved Substrate Preparation for Postheparin Plasma Lipase (1966) (3)
- ON INTERPRETING VARIATIONS IN LABORATORY TESTS AS ILLUSTRATED BY AN ANALYSIS OF LIVER FUNCTION TESTS. (1964) (3)
- Thyroid clearance, uptake, and rate of uptake of radioiodine in hyperthyroidism: their interrelationships and diagnostic value. (1957) (3)
- Inhibitory neuromodulators do not alter the course of experimental hepatic encephalopathy (1988) (3)
- Ammonia: The Old and the New (1984) (3)
- Splenic protein synthesis in magnesium deficiency: mechanism of the inhibition. (1978) (2)
- Laboratory medicine: On Interpreting Variations in Laboratory Tests: AS ILLUSTRATED BY AN ANALYSIS OF LIVER FUNCTION TESTS (1964) (2)
- Studies of ammonia loading: Effects of rate of delivery and enhanced removal of NH4 on blood levels of ammonia and coma induction (1989) (2)
- What determines blood ammonia? (1979) (2)
- Clinical significance of the urine amylase excretion rate. (1962) (2)
- USE OF TRYPSIN TO ELIMINATE RESIDUAL SNAKE-VENOM PHOSPHOLIPASE A ACTIVITY IN LYSOLECITHIN PREPARED FROM OVOLECITHIN. (1963) (2)
- Methanethiol and derivatives in hepatic failure. (1988) (2)
- Studies of experimental hepatic encephalopathy. (1985) (2)
- Experimental study of visual perception and of Hull's conditioning theory. (1937) (2)
- Etiology of hyperalimentation coma. (1973) (2)
- Clinicopathologic conference: Minneapolis Veterans Administration Hospital. (1962) (1)
- Note on hepatic function one to three decades after an episode of jaundice during childhood. (1955) (1)
- An analysis of total RNA translation products of rat liver during regeneration with a comparison to fetal liver. (1989) (1)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. IV. Nature of the interrelationships among hepatic tests in cirrhosis. (1955) (1)
- Alterations in thyroid I-131 uptake, basal metabolic rate and serum cholesterol following treatment of hyperthyroidisim with radioactive iodine (1956) (1)
- Effects of magnesium deficiency on protein and nucleic acid synthesis in rat tissues (1972) (1)
- Influence of jaundice on turbidimetric measurement of serum lipolytic activity. (1966) (1)
- Biochemistry of Liver Failure (1992) (1)
- Valproic acid induction of coma in rats: Synergism with NH4+ and pentobarbital (1989) (1)
- The hepatic toxicity of amithiozone. (1951) (1)
- Urine amylase. (1961) (1)
- Evolution of clinical enzyme tests. 3. Phospholipase A. (1966) (0)
- Quantiative estimation of some phosphatides and their hydrolysis products by thin layer chromatography. (1963) (0)
- Auto-immunity in thyroid diseases. (1959) (0)
- Chronic schistosomiasis japonica diagnosed by rectal biopsy; report of case. (1948) (0)
- Exchange transfusions in hepatic failure. (1970) (0)
- Zieve’s syndrome, an underdiagnosed entity (2022) (0)
- Laboratory notes: Pathogenesis of Hepatic Coma (1962) (0)
- EFFECT OF HEPARIN ON BLOOD AND TISSUE LIPIDS FOLLOWING CONTINUOUS INFUSIONS OF FAT IN RATS. (1964) (0)
- Evolution of clinical enzyme tests. I. Serum transaminase. (1966) (0)
- [The significance of hepatic function tests]. (1960) (0)
- Interrelationships among hepatic tests (1955) (0)
- The Hepatic Toxicity of Amithiozone1,2,3 (2019) (0)
- Misinterpretation and abuse of laboratory tests. (1968) (0)
- hepatic encephalopathy . liver disease with and without Blood methanethiol in alcoholic (2006) (0)
- Effect of sorbitol on psychomotor function in alcoholic cirrhosis (1978) (0)
- The importance of statistics to the physician. (1954) (0)
- Simplification in the measurement of total fecal fat. (1961) (0)
- Evolution of clinical enzyme tests. 2. Serum lipase. (1966) (0)
- Comparative importance of severity and therapeutic effort in determining the outcome of diabetic acidosis as observed in a representative group of patients. (1954) (0)
- Effect of methanethiol on erythrocyte membrane stabilization and Na+,K+ ATPase activity at 37°C (1976) (0)
- Depression of coproporphyrin excretion by amithiozone. (1953) (0)
- Correspondence (0)
- Invited commentary (1980) (0)
- Effect of endotoxin and immunoglobulin on the course of experimental hepatic encephalopathy (1988) (0)
- An evaluation of factors influencing the discriminative effectiveness of a group of liver function tests. V. Relative effectiveness of hepatic tests in viral hepatitis. (1955) (0)
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