Laimonis Laimins
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Laimonis Laimins's Degrees
- PhD Microbiology University of California, San Francisco
- Masters Immunology Harvard University
- Bachelors Biology Stanford University
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Why Is Laimonis Laimins Influential?
(Suggest an Edit or Addition)According to Wikipedia, Laimonis A. Laimins is an American microbiologist currently the Guy and Anne Youmans Professor at Northwestern University and an Elected Fellow of the American Association for the Advancement of Science.
Laimonis Laimins's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Human papillomavirus oncoproteins: pathways to transformation (2010) (1464)
- Pathogenesis of Human Papillomaviruses in Differentiating Epithelia (2004) (678)
- Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. (1992) (459)
- Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. (1982) (409)
- Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. (1988) (392)
- Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation (2009) (358)
- Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity (2006) (355)
- Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53 (1993) (343)
- Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target (1992) (341)
- Microarray Analysis Identifies Interferon-Inducible Genes and Stat-1 as Major Transcriptional Targets of Human Papillomavirus Type 31 (2000) (307)
- Persistence of human papillomavirus infection: keys to malignant progression. (2011) (301)
- Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes (1992) (291)
- Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation (1991) (287)
- Human papillomavirus life cycle: active and latent phases. (1999) (285)
- Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation (2003) (283)
- Osmotic control of kdp operon expression in Escherichia coli. (1981) (274)
- Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53‐mediated repression of transcription. (1992) (271)
- Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus (1984) (264)
- Telomerase Activation by Human Papillomavirus Type 16 E6 Protein: Induction of Human Telomerase Reverse Transcriptase Expression through Myc and GC-Rich Sp1 Binding Sites (2001) (248)
- Inhibition of p53 DNA binding by human papillomavirus E6 proteins (1994) (234)
- In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression. (1996) (210)
- Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes. (1999) (205)
- Human Papillomavirus Type 31 E5 Protein Supports Cell Cycle Progression and Activates Late Viral Functions upon Epithelial Differentiation (2003) (205)
- Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers (2012) (191)
- Transcriptional "silencer" element in rat repetitive sequences associated with the rat insulin 1 gene locus. (1986) (187)
- The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells (1987) (179)
- Human Papillomaviruses Modulate Expression of MicroRNA 203 upon Epithelial Differentiation to Control Levels of p63 Proteins (2010) (177)
- Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus (2019) (176)
- c-Myc induces the expression and activity of ornithine decarboxylase. (1993) (172)
- The Binding of Histone Deacetylases and the Integrity of Zinc Finger-Like Motifs of the E7 Protein Are Essential for the Life Cycle of Human Papillomavirus Type 31 (2004) (168)
- Identification of human papillomavirus type 18 transforming genes in immortalized and primary cells (1989) (167)
- Human papillomavirus E7 oncoproteins bind a single form of cyclin E in a complex with cdk2 and p107. (1996) (159)
- Human Papillomavirus Oncoproteins E6 and E7 Independently Abrogate the Mitotic Spindle Checkpoint (1998) (156)
- Role of the E1∧E4 Protein in the Differentiation-Dependent Life Cycle of Human Papillomavirus Type 31 (2005) (155)
- Role of the PDZ Domain-Binding Motif of the Oncoprotein E6 in the Pathogenesis of Human Papillomavirus Type 31 (2004) (155)
- The E8^E2C Protein, a Negative Regulator of Viral Transcription and Replication, Is Required for Extrachromosomal Maintenance of Human Papillomavirus Type 31 in Keratinocytes (2000) (146)
- Binding of the human papillomavirus E1 origin-recognition protein is regulated through complex formation with the E2 enhancer-binding protein. (1994) (145)
- Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding (1993) (134)
- Nuclear Accumulation of the Papillomavirus E1 Helicase Blocks S-Phase Progression and Triggers an ATM-Dependent DNA Damage Response (2011) (130)
- Activation of Papillomavirus Late Gene Transcription and Genome Amplification upon Differentiation in Semisolid Medium Is Coincident with Expression of Involucrin and Transglutaminase but Not Keratin-10 (1998) (124)
- Human papillomavirus E7 enhances hypoxia-inducible factor 1-mediated transcription by inhibiting binding of histone deacetylases. (2011) (119)
- Potassium transport in Escherichia coli: diverse systems with common control by osmotic forces (1980) (118)
- Roles of the E6 and E7 Proteins in the Life Cycle of Low-Risk Human Papillomavirus Type 11 (2004) (113)
- Histone deacetylase 3 localizes to the plasma membrane and is a substrate of Src (2006) (111)
- Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification (2007) (111)
- Multiple enhancer domains in the 3' terminus of the Prague strain of Rous sarcoma virus. (1984) (110)
- The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro (1991) (108)
- Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses. (2009) (108)
- Transactivation by the E2 Protein of Oncogenic Human Papillomavirus Type 31 Is Not Essential for Early and Late Viral Functions (1998) (107)
- Differential Requirements for Conserved E2 Binding Sites in the Life Cycle of Oncogenic Human Papillomavirus Type 31 (1998) (103)
- A keratinocyte-specific transcription factor, KRF-1, interacts with AP-1 to activate expression of human papillomavirus type 18 in squamous epithelial cells. (1991) (103)
- Suppression of STAT-1 Expression by Human Papillomaviruses Is Necessary for Differentiation-Dependent Genome Amplification and Plasmid Maintenance (2011) (98)
- The role of the E1 and E2 proteins in the replication of human papillomavirus type 31b. (1994) (97)
- In vitro systems for the study and propagation of human papillomaviruses. (1994) (93)
- The biology of human papillomaviruses: from warts to cancer. (1993) (92)
- Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates (1997) (90)
- The full-length E1E4 protein of human papillomavirus type 18 modulates differentiation-dependent viral DNA amplification and late gene expression. (2007) (89)
- Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18 (1988) (89)
- Differentiation-induced changes in promoter usage for transcripts encoding the human papillomavirus type 31 replication protein E1. (1999) (88)
- Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4. (2007) (86)
- Differentiation of HPV-containing cells using organotypic "raft" culture or methylcellulose. (2005) (83)
- Human Papillomavirus Genotype 31 Does Not Express Detectable MicroRNA Levels during Latent or Productive Virus Replication (2006) (82)
- Human papillomaviruses: shared and distinct pathways for pathogenesis. (2015) (82)
- The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation (2013) (82)
- Human papillomavirus type 31b late gene expression is regulated through protein kinase C-mediated changes in RNA processing (1995) (81)
- Human Papillomaviruses Modulate MicroRNA 145 Expression To Directly Control Genome Amplification (2013) (80)
- Bap31 Is a Novel Target of the Human Papillomavirus E5 Protein (2008) (79)
- Expression of AP1 during cellular differentiation determines human papillomavirus E6/E7 expression in stratified epithelial cells. (1997) (79)
- Human papillomavirus oncoproteins alter differentiation-dependent cell cycle exit on suspension in semisolid medium. (1998) (74)
- Differentiation-Dependent Chromatin Rearrangement Coincides with Activation of Human Papillomavirus Type 31 Late Gene Expression (2001) (70)
- Human papillomaviruses and the interferon response. (2009) (70)
- Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity (1997) (70)
- Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector (1989) (69)
- Human papillomaviruses target the double-stranded RNA protein kinase pathway. (2006) (69)
- Functional organization of the kdp genes of Escherichia coli K-12 (1978) (67)
- Cellular Changes Induced by Low-Risk Human Papillomavirus Type 11 in Keratinocytes That Stably Maintain Viral Episomes (2001) (67)
- The role of human papillomaviruses in oncogenesis. (2014) (66)
- DNA Replication of Human Papillomavirus Type 31 Is Modulated by Elements of the Upstream Regulatory Region That Lie 5′ of the Minimal Origin (1999) (65)
- STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication (2015) (65)
- E6 protein of human papillomavirus type 18 binds zinc. (1989) (64)
- Identification of the structural proteins of an ATP-driven potassium transport system in Escherichia coli. (1978) (64)
- The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes (2015) (63)
- Regulation of human papillomavirus type 31 gene expression during the differentiation-dependent life cycle through histone modifications and transcription factor binding. (2008) (63)
- Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator. (1992) (63)
- In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions. (1990) (60)
- Mechanisms regulating expression of the HPV 31 L1 and L2 capsid proteins and pseudovirion entry (2007) (56)
- Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification (2018) (56)
- Induction of the Human Papillomavirus Type 31 Late Promoter Requires Differentiation but Not DNA Amplification (2005) (55)
- Corrigendum: Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription (The EMBO Journal(1992)11(3045-3052)) (1992) (55)
- The Fanconi Anemia Pathway Limits Human Papillomavirus Replication (2012) (54)
- Nuclear Export of Human Papillomavirus Type 31 E1 Is Regulated by Cdk2 Phosphorylation and Required for Viral Genome Maintenance (2010) (54)
- Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication (2017) (53)
- Differentiation-dependent expression of E1--E4 proteins in cell lines maintaining episomes of human papillomavirus type 31b. (1995) (53)
- Long-Term Effect of Interferon on Keratinocytes That Maintain Human Papillomavirus Type 31 (2002) (53)
- Activation of human papillomavirus type 18 gene expression by herpes simplex virus type 1 viral transactivators and a phorbol ester (1989) (53)
- Early Polyadenylation Signals of Human Papillomavirus Type 31 Negatively Regulate Capsid Gene Expression (2001) (51)
- An Interaction between Human Papillomavirus 16 E2 and TopBP1 Is Required for Optimum Viral DNA Replication and Episomal Genome Establishment (2012) (51)
- p63 Is Necessary for the Activation of Human Papillomavirus Late Viral Functions upon Epithelial Differentiation (2011) (51)
- Regulation of Human Papillomavirus Type 31 Polyadenylation during the Differentiation-Dependent Life Cycle (1999) (50)
- Transcriptional activity of human papillomavirus type 31b enhancer is regulated through synergistic interaction of AP1 with two novel cellular factors. (1995) (50)
- Cooperative binding of the E2 protein of bovine papillomavirus to adjacent E2-responsive sequences (1991) (50)
- Human Papillomaviruses Activate and Recruit SMC1 Cohesin Proteins for the Differentiation-Dependent Life Cycle through Association with CTCF Insulators (2015) (49)
- Human Papillomavirus E1 Helicase Interacts with the WD Repeat Protein p80 To Promote Maintenance of the Viral Genome in Keratinocytes (2007) (48)
- The E7 Open Reading Frame Acts in cis and in trans To Mediate Differentiation-Dependent Activities in the Human Papillomavirus Type 16 Life Cycle (2011) (47)
- Regulation of the life cycle of HPVs by differentiation and the DNA damage response. (2013) (47)
- Human Papillomavirus Type 31 Replication Modes during the Early Phases of the Viral Life Cycle Depend on Transcriptional and Posttranscriptional Regulation of E1 and E2 Expression (2002) (45)
- Manipulation of the innate immune response by human papillomaviruses. (2017) (45)
- The 5' region of the human papillomavirus type 31 upstream regulatory region acts as an enhancer which augments viral early expression through the action of YY1. (1997) (44)
- Growth and differentiation of human papillomavirus type 31b positive human cervical cell lines. (1993) (44)
- A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK-cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression. (2011) (43)
- Human papillomaviruses target differentiating epithelia for virion production and malignant conversion (1996) (42)
- The Acetyltransferase Tip60 Is a Critical Regulator of the Differentiation-Dependent Amplification of Human Papillomaviruses (2015) (42)
- Human Papillomavirus E6 Proteins Mediate Resistance to Interferon-Induced Growth Arrest through Inhibition of p53 Acetylation (2007) (39)
- Long interspersed repeated DNA (LINE) causes polymorphism at the rat insulin 1 locus (1985) (36)
- Human papilloma viruses and cervical tumours: mapping of integration sites and analysis of adjacent cellular sequences (2002) (32)
- Differential effects of the splice acceptor at nucleotide 3295 of human papillomavirus type 31 on stable and transient viral replication (1997) (30)
- Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle (2016) (30)
- Human Papillomavirus Type 31 Replication Modes during the Early Phases of the Viral Life Cycle Depend on Transcriptional and Posttranscriptional Regulation of E1 and E2 Expression (2002) (29)
- FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication (2017) (29)
- Human papillomavirus type 31 life cycle: methods for study using tissue culture models. (2005) (28)
- Differentiation-Dependent Changes in Levels of C/EBPβ Repressors and Activators Regulate Human Papillomavirus Type 31 Late Gene Expression (2012) (25)
- The differentiation-dependent life cycle of human papillomaviruses in keratinocytes (2007) (24)
- Atypical squamous cells. A case-series study of the association between papanicolaou smear results and human papillomavirus DNA genotype. (1991) (24)
- The Life Cycle of Human Papillomaviruses (2009) (22)
- Analysis of the roles of E6 binding to E6TP1 and nuclear localization in the human papillomavirus type 31 life cycle. (2007) (22)
- Human papillomaviruses: research priorities for the next decade. (2016) (21)
- Interferon-Inducible Genes Are Major Targets of Human Papillomavirus Type 31: Insights from Microarray Analysis (2002) (21)
- E6 and E7 expression from the HPV 18 LCR: development of genital hyperplasia and neoplasia in transgenic mice. (1995) (20)
- Human papillomavirus E5 oncoproteins bind the A4 endoplasmic reticulum protein to regulate proliferative ability upon differentiation. (2014) (20)
- Mechanisms of Potassium Transport in Bacteria (1982) (19)
- p38MAPK and MK2 Pathways Are Important for the Differentiation-Dependent Human Papillomavirus Life Cycle (2014) (18)
- Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors (2020) (16)
- Suppression of MicroRNA 424 Levels by Human Papillomaviruses Is Necessary for Differentiation-Dependent Genome Amplification (2017) (16)
- HPV-16 viral transcripts in vulvar neoplasia: preliminary studies. (1991) (14)
- Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally. (1991) (13)
- Regulation of Transcription and Replication by Human Papillomaviruses (1998) (13)
- EBNA1 and E2: a new paradigm for origin-binding proteins? (1996) (13)
- Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection (2021) (10)
- Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway (2020) (9)
- Expression of HPV-induced DNA Damage Repair Factors Correlates With CIN Progression (2019) (9)
- Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV positive cells for genome amplification upon epithelial differentiation (2018) (8)
- Activation of DNA damage repair factors in HPV positive oropharyngeal cancers. (2020) (8)
- Viral transformation of epithelial cells. (2013) (8)
- Regulation of human papillomavirus gene expression in the vegetative life cycle (2002) (6)
- Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication (2021) (5)
- CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits. (2014) (5)
- Human Papillomavirus E 6 Proteins Mediate Resistance to Interferon-Induced Growth Arrest through Inhibition of p 53 Acetylation (2007) (5)
- Tumor and Stem Cell Biology Human Papillomavirus E 7 Enhances Hypoxia-Inducible Factor 1 – Mediated Transcription by Inhibiting Binding of Histone Deacetylases (2011) (5)
- High-Risk Human Papillomaviruses and DNA Repair. (2021) (4)
- Virology under the Microscope—a Call for Rational Discourse (2023) (4)
- The Molecular Pathogenesis of Human Papillomavirus-Associated Cancer (2004) (3)
- Human papillomaviruses sensitize cells to DNA damage induced apoptosis by targeting the innate immune sensor cGAS (2022) (3)
- Osmotic control ofkdpoperon expression inEscherichia coli (1981) (2)
- Introduction: Viruses in human cancers (1996) (2)
- Tumor and Stem Cell Biology CD 66 þ Cells in Cervical Precancers Are Partially Differentiated Progenitors with Neoplastic Traits (2014) (2)
- Author Correction: Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus (2019) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Modulation of epithelial differentiation by the E6 and E7 oncoproteins of human papillomaviruses (1995) (1)
- Virology under the Microscope—a Call for Rational Discourse (2023) (1)
- Genomic Instability and DNA Damage Repair Pathways Induced by Human Papillomaviruses (2021) (1)
- Observations associated with non-linear voltage-current characteristics of type II superconductors (1973) (0)
- Author Correction: Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus (2022) (0)
- The Action of E6 and E7 of Human Papillomaviruses in Cellular Immortalization and Transformation (2001) (0)
- Biology: Oncoproteins and malignancy (2004) (0)
- 3H-labeled subgenomic mRNA probes can demonstrate subtle differences in human papilloma virus expression in preinvasive and invasive vulvar cancers (1991) (0)
- 133 Translation and transforming activity of a circular RNA from human papillomavirus (2019) (0)
- Osmotic control of kdp operon expr (potassium transport/lac fusion/turgor pressure) (2016) (0)
- Mechanical regulation of gene expression osmotic control of the kdp system of escherichia coli (1980) (0)
- Microarray Analysis of Human Papillomavirus Pathogenesis (2002) (0)
- Identification of HPV 31B in human cervical cells grown on raised collagen gel rafts (1991) (0)
- Histone Deacetylases Mediated Transcription by Inhibiting Binding of - Factor 1 Human Papillomavirus E7 Enhances Hypoxia-Inducible (2011) (0)
- Correlation of human papillomavirus DNA type and presence of atypical squamous cells in Pap smears (1989) (0)
- Establishmentand Episomal Genome Required for Optimum Viral DNA Papillomavirus 16 E2 and TopBP1 Is An Interaction between Human (2014) (0)
- G102 Activation of differentiation-dependent human papillomavirus life cycle through the ATM DNA damage pathway (2013) (0)
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