Chen Lan-bo
#126,417
Most Influential Person Now
Taiwanese biotechnologist
Chen Lan-bo's AcademicInfluence.com Rankings
Chen Lan-bobiology Degrees
Biology
#8505
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#11596
Historical Rank
Biotechnology
#197
World Rank
#199
Historical Rank
Genetics
#1272
World Rank
#1374
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Molecular Biology
#1621
World Rank
#1649
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Biology
Chen Lan-bo's Degrees
- PhD Biotechnology National Taiwan University
- Masters Biotechnology National Taiwan University
- Bachelors Biotechnology National Taiwan University
Why Is Chen Lan-bo Influential?
(Suggest an Edit or Addition)According to Wikipedia, Chen Lan-bo is a Taiwanese biotechnologist. He was a professor of pathology at Harvard Medical School between 1977 and 2004 and is the author of over 250 publications. He is also a member of Boston's Dana-Farber Cancer Institute in the department of cancer and biology and a member of the Academia Sinica of Taiwan.
Chen Lan-bo's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Localization of mitochondria in living cells with rhodamine 123. (1980) (1451)
- Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. (1991) (1432)
- Mitochondrial membrane potential in living cells. (1988) (970)
- J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. (1991) (969)
- Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy (1981) (898)
- Mitochondrial membrane potential monitored by JC-1 dye. (1995) (642)
- Microtubules and the endoplasmic reticulum are highly interdependent structures (1986) (622)
- Mitogenic activity of blood components. I. Thrombin and prothrombin. (1975) (454)
- Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells. (1985) (385)
- Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. (1994) (384)
- Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system. (1991) (353)
- Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells. (1982) (349)
- Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. (2000) (282)
- Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29). (1996) (242)
- Selective toxicity of rhodamine 123 in carcinoma cells in vitro. (1983) (238)
- Presence of an SH2 domain in the actin-binding protein tensin. (1991) (220)
- Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye. (1983) (218)
- Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation. (1987) (213)
- The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. (1998) (202)
- Correlation between tumor induction and the large external transformation sensitive protein on the cell surface. (1976) (190)
- BCR/ABL induces multiple abnormalities of cytoskeletal function. (1997) (188)
- Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein. (1988) (183)
- Probing mitochondria in living cells with rhodamine 123. (1982) (182)
- MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation. (1996) (177)
- Interactions of tensin with actin and identification of its three distinct actin-binding domains (1994) (166)
- Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro. (1982) (165)
- Construction of the endoplasmic reticulum (1989) (156)
- Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. (1995) (156)
- Increased rhodamine 123 uptake by carcinoma cells. (1985) (155)
- Analysis of MHC class II presentation of particulate antigens of B lymphocytes. (1996) (148)
- Detection of the large external transformation-sensitive protein on some epithelial cells. (1977) (138)
- Selective damage to carcinoma mitochondria by the rhodacyanine MKT-077. (1996) (134)
- Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria. (1984) (129)
- Control of a cell surface major glycoprotein by epidermal growth factor. (1977) (125)
- Effect of microtubules and intermediate filaments on mitochondrial distribution. (1983) (125)
- Two differentially expressed genes in normal human prostate tissue and in carcinoma. (1996) (121)
- The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cells. (1982) (116)
- Fluorescent labeling of mitochondria. (1989) (108)
- Detection of phosphotyrosine-containing 34,000-dalton protein in the framework of cells transformed with Rous sarcoma virus. (1981) (107)
- Mitogenicity of thrombin and surface alterations on mouse splenocytes. (1976) (99)
- The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha. (1999) (98)
- A phosphotyrosyl-protein phosphatase activity associated with acid phosphatase from human prostate gland. (1984) (97)
- Increased expression of human ribosomal phosphoprotein P0 messenger RNA in hepatocellular carcinoma and colon carcinoma. (1992) (96)
- Several endoplasmic reticulum stress proteins, including ERp72, interact with thyroglobulin during its maturation. (1994) (95)
- Structure-activity of novel rhodacyanine dyes as antitumor agents. (1998) (94)
- The significance of carbonic anhydrase expression in human colorectal cancer. (1993) (89)
- Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus. (1975) (89)
- Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system. (2000) (85)
- Expression of keratin and vimentin intermediate filaments in rabbit bladder epithelial cells at different stages of benzo[a]pyrene-induced neoplastic progression (1981) (84)
- Expression of a Mr 32,000 laminin-binding protein messenger RNA in human colon carcinoma correlates with disease progression. (1990) (83)
- Selective killing of carcinoma cells "in vitro" by lipophilic-cationic compounds: a cellular basis. (1985) (82)
- AA1, a newly synthesized monovalent lipophilic cation, expresses potent in vivo antitumor activity. (1994) (78)
- Molecular characterization of human tensin. (2000) (77)
- Detection of individual fluorescently labeled reovirions in living cells. (1990) (72)
- Ubiquitin-ribosomal protein S27a gene overexpressed in human colorectal carcinoma is an early growth response gene. (1993) (70)
- Gastric and hepatocellular carcinomas do not overexpress the same ribosomal protein messenger RNAs as colonic carcinoma. (1993) (70)
- Specific disruption of vimentin filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin A, and cycloheximide. (1980) (64)
- Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2. (1996) (63)
- BAX expression is associated with enhanced intracellular accumulation of paclitaxel: a novel role for BAX during chemotherapy-induced cell death. (1998) (62)
- Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement. (2001) (60)
- Nuclear localization of nucleoside diphosphate kinase type B (nm23-H2) in cultured cells. (1996) (59)
- Aberrant mitochondria in two human colon carcinoma cell lines. (1989) (58)
- Serum level of the periostin, a homologue of an insect cell adhesion molecule, in thymoma patients. (2001) (53)
- Characterization of a phosphotyrosyl protein phosphatase activity associated with a phosphoseryl protein phosphatase of Mr = 95,000 from bovine heart. (1983) (53)
- HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma. (1999) (53)
- Induction of cytoskeleton-associated proteins during differentiation of human myeloid leukemic cell lines. (1982) (52)
- Behavior of cells seeded in isolated fibronectin matrices (1983) (52)
- Binding and internalization of thrombin by normal and transformed chick cells. (1977) (51)
- Photosensitization by 3,3'-dihexyloxacarbocyanine iodide: specific disruption of microtubules and inactivation of organelle motility. (1995) (51)
- Association of the mammalian helicase MAH with the pre-mRNA splicing complex. (1997) (50)
- In vivo administration of MKT-077 causes partial yet reversible impairment of mitochondrial function. (1996) (49)
- Inhibition of rodent protein kinase C by the anticarcinoma agent dequalinium. (1990) (49)
- Increased expression of the epidermal growth factor receptor on human colon carcinoma cells. (1986) (48)
- Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts. (1975) (46)
- Inhibition of rat colon tumor isograft growth with dequalinium chloride. (1986) (46)
- Transcriptional inactivation of secreted frizzled-related protein 1 by promoter hypermethylation as a potential biomarker for non-small cell lung cancer. (2010) (45)
- Synthesis and evaluation of chalcogenopyrylium dyes as potential sensitizers for the photodynamic therapy of cancer. (1999) (45)
- Possible role of fibronectin in malignancy. (1979) (43)
- Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity. (1997) (42)
- Cytoskeleton-associated proteins of human lung cancer cells. (1983) (42)
- The prognostic significance of proliferating cell nuclear antigen in clinical gastric cancer. (1993) (40)
- Association of phenotypic reversion of transformed cells induced by interferon with morphological and biochemical changes in the cytoskeleton. (1981) (39)
- Photoactivation enhances the mitochondrial toxicity of the cationic rhodacyanine MKT-077. (1998) (37)
- Prothymosin-alpha mRNA expression correlates with that of c-myc in human colon cancer. (1993) (35)
- Cytotoxic effect of thiacarbocyanine dyes on human colon carcinoma cells and inhibition of bovine heart mitochondrial NADH-ubiquinone reductase activity via a rotenone-type mechanism by two of the dyes. (1993) (34)
- 2-Methoxyestardiol and bortezomib/proteasome-inhibitor overcome dexamethasone-resistance in multiple myeloma cells by modulating Heat Shock Protein-27 (2004) (32)
- Binding of 2-hydroxybenzo(a)pyrene to estrogen receptors in rat cytosol. (1986) (32)
- Direct effect of gossypol on TR-ST cells: perturbation of rhodamine 123 accumulation in mitochondria. (1984) (30)
- Studies of fibronectin matrices in living cells with fluoresceinated gelatin (1980) (27)
- Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine. (1996) (27)
- The bis-azo compound FP-21399 inhibits HIV-1 replication by preventing viral entry. (1998) (26)
- Treatment of Ras-induced cancers by the F-actin cappers tensin and chaetoglobosin K, in combination with the caspase-1 inhibitor N1445. (1999) (24)
- A fusion inhibitor (FP-21399) for the treatment of human immunodeficiency virus infection: a phase I study. (2000) (24)
- Ubiquitin fusion proteins are overexpressed in colon cancer but not in gastric cancer. (1995) (24)
- Ubiquitin hybrid protein gene expression during human colon cancer progression. (1991) (19)
- Cell types associated with fibronectin in long-term mouse bone marrow cultures. (1982) (18)
- A monoclonal antibody recognizing a keratin filament protein in a subset of transitional and glandular epithelia. (1984) (17)
- Overexpression of Hrad17 gene in non-small cell lung cancers correlated with lymph node metastasis. (2001) (17)
- Distribution of cell surface LETS protein in co-cultures of normal and transformed cells. (1977) (16)
- Measurement of apoptosis in heterogenous cell populations. (1997) (16)
- Loss of hIRH mRNA expression from premalignant adenomas and malignant cell lines. (1996) (16)
- Anticarcinoma activity of a novel drug, 3-ethyl-3'-methyl-thiatelluracarbocyanine iodide (Te), a tellurium-containing cyanine targeted at mitochondria. (1996) (15)
- Overexpression of HRad17 mRNA in human breast cancer: correlation with lymph node metastasis. (2001) (15)
- Quantitative differential effects of rhodamine 123 on normal cells and human colon cancer cells by magnetic resonance spectroscopy. (1993) (14)
- Nucleotide and deduced amino acid sequence of human ribosomal protein L18. (1993) (14)
- Differences in messenger RNA expression of carcinoembryonic antigen in surgical specimens of colorectal carcinoma. (1992) (13)
- 13C- and 31P-NMR studies of human colon cancer in-vitro and in-vivo. (1993) (12)
- Electron microscopic studies of the endoplasmic reticulum in whole-mount cultured cells fixed with potassium permanganate. (1991) (12)
- Alterations of gene expression in human colorectal cancer. Biological implications. (1990) (11)
- Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. (1994) (11)
- Localization of a Mr 52,000 keratin in basal epithelial cells of the mouse bladder and expression throughout neoplastic progression. (1982) (11)
- Photoelectron microscopy and immunofluorescence microscopy of cytoskeletal elements in the same cells. (1983) (10)
- Significance of the feline oncornavirus-associated cell-membrane antigen (FOCMA) in the natural history of feline leukemia. (1980) (8)
- Inhibition of bovine heart mitochondrial and Paracoccus denitrificans NADH----ubiquinone reductase by dequalinium chloride and three structurally related quinolinium compounds. (1989) (7)
- A cell surface glycoprotein expressed by colorectal carcinomas including poorly differentiated, noncarcinoembryonic antigen-producing colorectal tumors. (1988) (6)
- Motility and construction of the endoplasmic reticulum in living cells. (1993) (6)
- Removal of carcinoma cells from contaminated bone marrow using the lipophilic cation rhodamine 123. (1995) (4)
- F-actin inhibits protein kinase activity associated with the src-gene product. (1980) (4)
- Mitogenic response of cells in tissue culture to thrombin. (1978) (2)
- Rhodamine-123: Radioiodination and evaluation as an agent for imaging and radiotherapy of certain tumors (1985) (2)
- Correlation between permeability of membranes and germination rate of rice seeds. (1990) (1)
- Studies on the expression condition of male-sterile genes and fertility changes in An-NongS-1 (indica type) male-sterile rice. (1990) (1)
- Distribution of Cold Insoluble Globulin on Surface of Adenovirus-Transformed Rat Embryo Fibroblasts (1976) (0)
- Study on fertility of Annong s-1 photoperiod and temperature sensitive genic male-sterile rice. I. Investigation on anther and pollen by scanning electron-microscope. (1990) (0)
- Determination of MKT-077, a novel antineoplastic agent, in plasma samples by high-performance liquid chromatography and its application to pharmacokinetics in rats. (1999) (0)
- Microtubule motility driven construction of the endoplasmic reticulum in living cells (1988) (0)
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Chen Lan-bo is affiliated with the following schools:
