Lara Mahal
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American chemist
Lara Mahal's AcademicInfluence.com Rankings
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Chemistry
Lara Mahal's Degrees
- Bachelors Chemistry University of California, Berkeley
Why Is Lara Mahal Influential?
(Suggest an Edit or Addition)According to Wikipedia, Lara K. Mahal is an American chemist who is the Canada Excellence Research Chair in Glycomics at the University of Alberta in Edmonton, Alberta, Canada. She is also a Professor of Chemistry at the University of Alberta. She is notable both for her pioneering work establishing lectin microarrays as a new technology for glycomics, her work on miRNA regulation of glycosylation and her graduate work with Carolyn R. Bertozzi on unnatural carbohydrate incorporation. Work in her laboratory focuses on understanding the role of carbohydrates in human health using systems- and chemical biology-based approaches
Lara Mahal's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- FINO2 Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation (2018) (345)
- miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. (2011) (325)
- Development of a Lectin Microarray for the Rapid Analysis of Protein Glycopatterns (2005) (260)
- Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus (2012) (234)
- Identification of a conserved glycan signature for microvesicles. (2011) (224)
- Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins (2002) (218)
- Analyzing the dynamic bacterial glycome with a lectin microarray approach (2006) (217)
- A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis. (2017) (199)
- Dectin-1 Activation on Macrophages by Galectin-9 Promotes Pancreatic Carcinoma and Peritumoral Immune-Tolerance (2017) (197)
- A ratiometric lectin microarray approach to analysis of the dynamic mammalian glycome (2007) (183)
- Deciphering the glycocode: the complexity and analytical challenge of glycomics. (2007) (162)
- HIV-1 and microvesicles from T-cells share a common glycome, arguing for a common origin (2009) (160)
- Metabolic Delivery of Ketone Groups to Sialic Acid Residues (1998) (155)
- Glycomic analysis: an array of technologies. (2009) (122)
- New technologies for glycomic analysis: toward a systematic understanding of the glycome. (2011) (119)
- Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19 (2020) (108)
- Control of cell adhesion and growth with micropatterned supported lipid membranes (2001) (104)
- A lectin microarray approach for the rapid analysis of bacterial glycans (2006) (102)
- Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I (2002) (100)
- Cross-platform comparison of glycan microarray formats. (2014) (100)
- Complex N-Linked Glycans Serve as a Determinant for Exosome/Microvesicle Cargo Recruitment* (2014) (99)
- A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells (2001) (91)
- Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2 (2021) (81)
- Engineering Novel Cell Surface Receptors for Virus-mediated Gene Transfer* (1999) (75)
- A simple strategy for the creation of a recombinant lectin microarray. (2008) (69)
- Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode (2014) (64)
- Dot by dot: analyzing the glycome using lectin microarrays. (2013) (61)
- Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins. (2015) (57)
- Multi-level regulation of cellular glycosylation: from genes to transcript to enzyme to structure. (2016) (50)
- Differential Effects of Unnatural Sialic Acids on the Polysialylation of the Neural Cell Adhesion Molecule and Neuronal Behavior* (2002) (48)
- Transduction of glycan-lectin binding using near-infrared fluorescent single-walled carbon nanotubes for glycan profiling. (2011) (47)
- SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors (2021) (46)
- Low-temperature preparations of unimolecular nitroxide initiators for living free radical polymerizations (1997) (46)
- A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities (2021) (44)
- Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate affinity to modulate specific galectin-1/glycan lattice interactions (2015) (43)
- Sweet tasting chips: microarray-based analysis of glycans. (2009) (39)
- Glycomics: towards bioinformatic approaches to understanding glycosylation. (2008) (38)
- NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods* (2019) (38)
- Lectin microarrays for glycoprotein analysis. (2007) (38)
- A Cellular FRET-Based Sensor for β-O-GlcNAc, A Dynamic Carbohydrate Modification Involved in Signaling (2006) (37)
- Advances in Lectin Microarray Technology: Optimized Protocols for Piezoelectric Print Conditions (2013) (36)
- miRNA proxy approach reveals hidden functions of glycosylation (2015) (36)
- Combining 3D structure with glycan array data provides insight into the origin of glycan specificity. (2016) (35)
- Targeted in Vivo O-GlcNAc Sensors Reveal Discrete Compartment-specific Dynamics during Signal Transduction* (2010) (32)
- Human Milk Bacterial and Glycosylation Patterns Differ by Delivery Mode (2016) (31)
- Current Protocols in Chemical Biology (2009) (31)
- XBP1s activation can globally remodel N-glycan structure distribution patterns (2018) (30)
- Insights into miRNA regulation of the human glycome. (2014) (28)
- Impact of Bacterial Vaginosis, as Assessed by Nugent Criteria and Hormonal Status on Glycosidases and Lectin Binding in Cervicovaginal Lavage Samples (2015) (27)
- Training the next generation of biomedical investigators in glycosciences. (2016) (26)
- A Totally Radical Approach to the Control of Stereochemistry: Coupling of Prochiral Radicals with Chiral Nitroxyl Radicals (1997) (26)
- MicroRNA-424 Predicts a Role for β-1,4 Branched Glycosylation in Cell Cycle Progression* (2015) (24)
- Studying the Effects of Reproductive Hormones and Bacterial Vaginosis on the Glycome of Lavage Samples from the Cervicovaginal Cavity (2015) (24)
- Fabrication of an oriented lectin microarray. (2010) (24)
- Characterization of a high-affinity sialic acid-specific CBM40 from Clostridium perfringens and engineering of a divalent form. (2016) (22)
- O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites (2018) (21)
- NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. (2020) (21)
- The N-glycome regulates the endothelial-to-hematopoietic transition (2019) (18)
- Two-Photon, Ratiometric, Quantitative Fluorescent Probe Reveals Fluctuation of Peroxynitrite Regulated by Arginase 1. (2021) (18)
- Sweet Control: MicroRNA Regulation of the Glycome. (2020) (17)
- A One-Step Synthesis of Azide-Tagged Carbohydrates: Versatile Intermediates for Glycotechnology (2006) (17)
- A cellular FRET-based sensor for beta-O-GlcNAc, a dynamic carbohydrate modification involved in signaling. (2006) (15)
- Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis (2021) (15)
- Ratiometric lectin microarray analysis of the mammalian cell surface glycome. (2011) (15)
- Carbohydrate sulfation as a mechanism for fine-tuning Siglec ligands (2021) (15)
- Orientation of GST-tagged lectins via in situ surface modification to create an expanded lectin microarray for glycomic analysis. (2011) (14)
- Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity (2020) (14)
- Submicron Emitters Enable Reliable Quantification of Weak Protein-Glycan Interactions by ESI-MS. (2021) (14)
- Post-translation modifications. (2009) (13)
- SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation (2022) (12)
- Glycomic analysis of host-response reveals high mannose as a key mediator of influenza severity (2020) (11)
- Integrated Systems Analysis of the Murine and Human Pancreatic Cancer Glycomes Reveals a Tumor-Promoting Role for ST6GAL1 (2021) (9)
- Recombinant lectin microarrays for glycomic analysis. (2011) (9)
- Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility. (2018) (9)
- Sweet systems: technologies for glycomic analysis and their integration into systems biology (2021) (9)
- Age-Dependent Glycomic Response to the 2009 Pandemic H1N1 Influenza Virus and Its Association with Disease Severity (2020) (9)
- Catching bacteria with sugar. (2004) (8)
- The host glycomic response to pathogens. (2021) (7)
- Quantifying Biomolecular Interactions Using Slow Mixing Mode (SLOMO) Nanoflow ESI-MS (2022) (6)
- Prevaccination Glycan Markers of Response to an Influenza Vaccine Implicate the Complement Pathway (2022) (5)
- O-linked α2,3 sialylation defines stem cell populations in breast cancer (2022) (4)
- O-fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites (2018) (3)
- Metabolism and global protein glycosylation are differentially expressed in healthy and osteoarthritic equine carpal synovial fluid. (2020) (2)
- Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
- High-Throughput Analysis Reveals miRNA Upregulating α-2,6-Sialic Acid through Direct miRNA–mRNA Interactions (2022) (2)
- Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology (2012) (2)
- Mass Spectrometry-Based Shotgun Glycomics Using Labeled Glycan Libraries. (2022) (2)
- Author Correction: Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance (2021) (2)
- High-Throughput miRFluR Platform Identifies miRNA Regulating B3GLCT That Predict Peters' Plus Syndrome Phenotype, Supporting the miRNA Proxy Hypothesis. (2021) (2)
- Correction for Kurcon et al., miRNA proxy approach reveals hidden functions of glycosylation (2015) (1)
- Lectin Microarrays: Simple Tools for the Analysis of Complex Glycans (2010) (1)
- Sex-specific glycosylation of secreted immunomodulatory proteins in the filarial nematode Brugia malayi (2021) (1)
- Impact of Microbicide Formulation on Glycosylation and Innate Immunity in Cervicovaginal Fluid (2016) (1)
- Mass spectrometry-based shotgun glycomics for discovery of natural ligands of glycan-binding proteins. (2022) (1)
- Correction: miRNA proxy approach reveals hidden functions of glycosylation (Proceedings of the National Academy of Sciences of the United States of America (2015) 112, 23 (7327-7332) DOI: 10.1073/pnas.1502076112) (2015) (1)
- α2,6-Sialylation is Upregulated in Severe COVID-19 Implicating the Complement Cascade (2022) (1)
- Glycomic Analysis Reveals a Conserved Response to Bacterial Sepsis Induced by Different Bacterial Pathogens (2020) (1)
- Glycomic Analysis Identifies Pre-Vaccination Markers of Response to Influenza Vaccine, Implicating the Complement Pathway (2022) (0)
- HIV-1 interaction with an O-glycan-specific bacterial lectin enhances virus infectivity and cell-to-cell viral transfer (2023) (0)
- High‐throughput Assay and In Vivo Screen Identify α‐2,3‐sialylation of CD98 by ST3GAL1 and ST3GAL2 as Essential to Melanoma Survival (2022) (0)
- Deep learning explains the biology of branched glycans from single-cell sequencing data (2022) (0)
- α2,6-Sialylation Is Upregulated in Severe COVID-19, Implicating the Complement Cascade (2022) (0)
- Biological Consequences of HIV‐1 Interactions with Bacteria (2022) (0)
- Abstract 1915: Overturning the Paradigm of miRNA Regulation: Upregulation as a common mechanism of miRNA action (2023) (0)
- A Total Radical Approach to the Control of Stereochemistry: Coupling of Prochiral Radicals with Chiral Nitroxyl Radicals. (1997) (0)
- Polychlorinated Biphenyls Inhibit Amyloid Fibril Formation (2004) (0)
- Abstract 1985: SARS-CoV-2 infection alters the breast milk glycomic profile (2023) (0)
- Identification of melanoma-specific alterations in cell surface glycosylation. (2012) (0)
- miRNA Regulation of α‐2,6‐ Sialylation: Comprehensive Analysis of ST6GAL1 & 2 (2022) (0)
- Systems‐Based Analysis of the Pancreatic Cancer‐Specific Glycome Reveals ST6GAL1 as a Driver of Human and Murine Disease (2021) (0)
- Sweet Patterns:Decoding glycan control mechanisms using systems‐based approaches. (106.2) (2014) (0)
- Faculty Opinions recommendation of Sulfation patterns of glycosaminoglycans encode molecular recognition and activity. (2006) (0)
- Faculty Opinions recommendation of A fluid membrane-based soluble ligand-display system for live-cell assays. (2006) (0)
- Uncovering regulatory nodes in miRNA‐mediated regulation of glycome (608.7) (2014) (0)
- Cargo Recruitment Determinant for Exosome / Microvesicle Complex N-linked Glycans Serve as a Glycobiology and Extracellular Matrices (2014) (0)
- Sweet Packets: What Glycomics can tell us about Viruses and Microvesicles. (2010) (0)
- Characterization of a novel CBM from Clostridium perfringens (2016) (0)
- Discovery of Glycomimetic Ligands via Genetically-encoded Library of Phage displaying Mannose-peptides (2015) (0)
- Cracking the Glycocode: Finding the Signal in the Noise (2018) (0)
- Comprehensive Analysis of miRNA Regulation of MGAT3 Using the miRFluR Assay (2022) (0)
- Quantifying Carbohydrate-Active Enzyme Activity with Glycoprotein Substrates Using Electrospray Ionization Mass Spectrometry and Center-of-Mass Monitoring. (2021) (0)
- Integrated Systems-Analysis of the Human and Murine Pancreatic Cancer Glycomes Reveal a Tumor Promoting Role for ST6GAL1 (2021) (0)
- Elucidating the regulation and dynamics of O‐GlcNAc during signal transduction (2010) (0)
- Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket (2023) (0)
- Glycomic Profiling Unveils Association Between Serum Glycosylation and Antibody Responses to Influenza Vaccines (2021) (0)
- High-throughput analysis of B3GLCT regulation predicts phenotype of Peters’ Plus Syndrome in line with the miRNA Proxy Hypothesis (2021) (0)
- Synthesis of glucose‐β‐1,3‐fucose‐α‐O‐threonine/serine to identify critical epitope in Peters‐plus syndrome (792.1) (2014) (0)
- CORRECTION (2017) (0)
- N-Glycome regulation limits the transdifferentiation of endothelial cells into hematopoietic stem cells (2019) (0)
- An Integrated Systems Approach to Deconstructing Glycosylation (2011) (0)
- Faculty Opinions recommendation of The repertoire of glycan determinants in the human glycome. (2009) (0)
- Reduced inflammatory response and promoted multiciliated cell differentiation in mice protected by defective interfering influenza virus (2022) (0)
- microRNA define the glycocode: identification of critical glycogenes that shape the cell (788.6) (2014) (0)
- Molecular imaging via novel application of fluorescent lectins permits rapid endoscopic identification of dysplasia in barrett's oesophagus (2011) (0)
- CBM40_CPF0721-6'SL (2016) (0)
- Faculty Opinions recommendation of Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. (2007) (0)
- miRNA upregulate protein and glycan expression via direct activation in proliferating cells (2022) (0)
- Molecular Imaging via Novel Application of Fluorescent Lectins Permits Rapid Endoscopic Identification of Dysplasia in Barrett's Esophagus (2011) (0)
- Microvesicles from various sources display a common glycomic signature (2011) (0)
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