Larry E. Overman
#51,161
Most Influential Person
American chemist
Why Is Larry E. Overman Influential?
(Suggest an Edit or Addition)Larry E. Overman is the Distinguished Professor of Chemistry at the University of California at Irvine. He earned a B.A. from Earlham College and a Ph.D. in chemistry from the University of Wisconsin at Madison.
Best known for his Claisen rearrangement of allylic alcohols in order to give allylic trichloroacetamides, known as the Overman rearrangement, Overman has focused on the discovery and development of new chemical reactions. His early work at the comparatively small laboratory at the University of California at Irvine sparked a lifetime love for rearrangement reactions, an interest that has yielded valuable data and strategies for studying catalysis of palladium.
Overman is a member of the American Academy of Arts and Sciences and the United States National Academy of Sciences. He has a number of scientific works to his credit, including “Molecular Rearrangements in the Construction of Complex Molecules”, and “Thermal and mercuric ion catalyzed [3,3]-sigmatropic rearrangement of allylic trichloroacetimidates. 1,3 Transposition of alcohol and amine functions”.
In 2008, Overman was honored with the Tetrahedron Prize for Creativity in Organic Chemistry and in 2015, he was awarded the Ryoji Noyori Prize. He has also been recognized as an Alfred P. Sloan Foundation Fellow (1975-1977) and a Guggenheim Fellow (1993).
Featured in Top Influential Chemists Today
According to Wikipedia, Larry E. Overman is Distinguished Professor of Chemistry at the University of California, Irvine. He was born in Chicago in 1943. Overman obtained a B.A. degree from Earlham College in 1965, and he completed his Ph.D. in chemistry from the University of Wisconsin–Madison in 1969, under Howard Whitlock Jr. Professor Overman is a member of the United States National Academy of Sciences and the American Academy of Arts and Sciences. He was the recipient of the Arthur C. Cope Award in 2003, and he was awarded the Tetrahedron Prize for Creativity in Organic Chemistry for 2008.
Larry E. Overman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- The asymmetric intramolecular Heck reaction in natural product total synthesis. (2003) (1079)
- Catalytic asymmetric synthesis of all-carbon quaternary stereocenters. (2004) (588)
- Catalytic enantioselective synthesis of quaternary carbon stereocentres (2014) (566)
- Total synthesis of complex cyclotryptamine alkaloids: stereocontrolled construction of quaternary carbon stereocenters. (2007) (333)
- An "artificial enzyme" combining a metal catalytic group and a hydrophobic binding cavity. (1970) (255)
- Contiguous stereogenic quaternary carbons: a daunting challenge in natural products synthesis. (2004) (242)
- A general method for the synthesis of amines by the rearrangement of allylic trichloroacetimidates. 1,3 Transposition of alcohol and amine functions (1976) (237)
- Vinylsilane- and alkynylsilane-terminated cyclization reactions (1986) (229)
- Intramolecular alkene arylations for rapid assembly of polycyclic systems containing quaternary centers. A new synthesis of spirooxindoles and other fused and bridged ring systems (1987) (227)
- Mercury(II)‐ and Palladium(II)‐Catalyzed [3,3]‐Sigmatropic Rearrangements [New Synthetic Methods (46)] (1984) (220)
- Catalytic asymmetric intramolecular aminopalladation: enantioselective synthesis of vinyl-substituted 2-oxazolidinones, 2-imidazolidinones, and 2-pyrrolidinones. (2002) (212)
- Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling. (2015) (209)
- A concise synthesis of (-)-aplyviolene facilitated by a strategic tertiary radical conjugate addition. (2012) (201)
- Strategic use of pinacol-terminated Prins cyclizations in target-oriented total synthesis. (2003) (188)
- Catalytic asymmetric rearrangement of allylic trichloroacetimidates. A practical method for preparing allylic amines and congeners of high enantiomeric purity. (2003) (187)
- Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms. (2016) (183)
- Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Investigations of Intramolecular Heck Reactions of (E)-α,β-Unsaturated 2-Haloanilides and Analogues To Form Enantioenriched Spirocyclic Products (1998) (180)
- Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates. (2013) (179)
- Design and in vitro pharmacology of a selective gamma-aminobutyric acidC receptor antagonist. (1996) (176)
- Enantioselective Total Synthesis of (-)-Ptilomycalin A (1995) (171)
- Direct Stereo- and Enantiocontrolled Synthesis of Vicinal Stereogenic Quaternary Carbon Centers. Total Syntheses of meso- and (−)-Chimonanthine and (+)-Calycanthine (1999) (157)
- Total synthesis of the strychnos alkaloid (+)-minfiensine: tandem enantioselective intramolecular Heck-iminium ion cyclization. (2008) (157)
- Allylic and propargylic imidic esters in organic synthesis (1980) (155)
- Catalytic asymmetric synthesis of quaternary carbons bearing two aryl substituents. Enantioselective synthesis of 3-alkyl-3-aryl oxindoles by catalytic asymmetric intramolecular heck reactions. (2003) (152)
- Constructing Quaternary Carbons from N-(Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis. (2015) (145)
- Palladium-catalyzed polyene cyclizations of trienyl triflates (1989) (144)
- Thermal and mercuric ion catalyzed [3,3]-sigmatropic rearrangement of allylic trichloroacetimidates. 1,3 Transposition of alcohol and amine functions (1974) (142)
- Charge as a key component in reaction design. The invention of cationic cyclization reactions of importance in synthesis (1992) (142)
- Asymmetric synthesis of pyrrolidinoindolines. Application for the practical total synthesis of (-)-phenserine. (2004) (141)
- Catalytic asymmetric synthesis of quarternary carbon centers. Palladium-catalyzed formation of either enantiomer of spirooxindoles and related spirocyclics using a single enantiomer of a chiral diphosphine ligand (1992) (139)
- Modeling chemical reactivity. 1. Regioselectivity of Diels-Alder cycloadditions of electron-rich dienes with electron-deficient dienophiles (1986) (134)
- Fragment Coupling with Tertiary Radicals Generated by Visible-Light Photocatalysis. (2016) (130)
- Asymmetric synthesis of either enantiomer of opium alkaloids and morphinans. Total synthesis of (-)- and (+)-dihydrocodeinone and (-)- and (+)-morphine (1993) (130)
- Enantioselective total synthesis of (+)-gliocladine C: convergent construction of cyclotryptamine-fused polyoxopiperazines and a general approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors. (2011) (129)
- Palladium-catalyzed polyene cyclizations of dienyl aryl iodides (1988) (127)
- Catalytic asymmetric rearrangement of allylic N-aryl trifluoroacetimidates. A useful method for transforming prochiral allylic alcohols to chiral allylic amines. (2003) (127)
- Sequential catalytic asymmetric Heck-iminium ion cyclization: enantioselective total synthesis of the Strychnos alkaloid minfiensine. (2005) (122)
- Synthesis applications of cationic aza-Cope rearrangements. 26. Enantioselective total synthesis of (-)-strychnine (1993) (116)
- First total synthesis of scopadulcic acid B (1993) (114)
- Is there no end to the total syntheses of strychnine? Lessons learned in strategy and tactics in total synthesis. (2012) (113)
- Enantioselective total synthesis of quadrigemine C and psycholeine. (2002) (113)
- Application of intramolecular Heck reactions for forming congested quaternary carbon centers in complex molecule total synthesis (1994) (111)
- Terminating Catalytic Asymmetric Heck Cyclizations by Stereoselective Intramolecular Capture of η-Allylpalladium Intermediates: Total Synthesis of (-)-Spirotryprostatin B and Three Stereoisomers. (2000) (109)
- The tethered Biginelli condensation in natural product synthesis. (2004) (108)
- ASYMMETRIC TOTAL SYNTHESES OF (-)- AND (+)-STRYCHNINE AND THE WIELAND-GUMLICH ALDEHYDE (1995) (105)
- Catalytic asymmetric synthesis of chiral allylic amines. Evaluation of ferrocenyloxazoline palladacycle catalysts and imidate motifs. (2005) (104)
- Enantiodivergent Total Syntheses of (+)- and (−)-Scopadulcic Acid A (1999) (104)
- Catalytic asymmetric synthesis of either enantiomer of physostigmine. Formation of quaternary carbon centers with high enantioselection by intramolecular Heck reactions of (Z)-2-butenanilides (1993) (102)
- Total synthesis of (-)-laurenyne. Use of acetal-initiated cyclizations to prepare functionalized eight-membered cyclic ethers (1988) (100)
- Use of the intramolecular Heck reaction for forming congested quaternary carbon stereocenters. Stereocontrolled total synthesis of (+/-)-gelsemine. (2005) (98)
- First total synthesis of Lycopodium alkaloids of the magellanane group. Enantioselective total syntheses of (-)-magellanine and (+)-magellaninone (1993) (96)
- Kinetic and computational analysis of the palladium(II)-catalyzed asymmetric allylic trichloroacetimidate rearrangement: development of a model for enantioselectivity. (2007) (93)
- First Enantioselective Catalyst for the Rearrangement of Allylic Imidates to Allylic Amides (1997) (93)
- Stereocontrolled Total Syntheses of meso-Chimonanthine and meso-Calycanthine via a Novel Samarium Mediated Reductive Dialkylation (1996) (91)
- Total Synthesis of (±)-Actinophyllic Acid (2008) (89)
- Total synthesis of (+/-)- and (-)-actinophyllic acid. (2010) (88)
- High Enantioselection in the Rearrangement of Allylic Imidates with Ferrocenyl Oxazoline Catalysts (1999) (88)
- Enantioselective total syntheses of ditryptophenaline and ent-WIN 64821. (2001) (88)
- Face selectivity in Diels-Alder reactions of chiral dienes containing allylic substituents (1988) (88)
- Construction of quaternary carbon centers by palladium-catalyzed intramolecular alkene insertions. Total synthesis of the Amaryllidaceae alkaloids (.+-.)-tazettine and (.+-.)-6a-epipretazettine (1990) (87)
- Catalytic asymmetric synthesis of chiral allylic esters. (2005) (86)
- Monomeric cobalt oxazoline palladacycles (COP). Useful catalysts for catalytic asymmetric rearrangement of allylic trichloroacetimidates. (2004) (85)
- Total Synthesis of (+)-Laurencin. Use of Acetal-Vinyl Sulfide Cyclizations for Forming Highly Functionalized Eight-Membered Cyclic Ethers (1995) (85)
- Use of aza-Cope rearrangement-Mannich cyclization reactions to achieve a general entry to Melodinus and Aspidosperma alkaloids. Stereocontrolled total syntheses of (.+-.)-deoxoapodine, (.+-.)-meloscine, and (.+-.)-epimeloscine and a formal synthesis of (.+-.)-1-acetylaspidoalbidine (1991) (84)
- Stereocontrolled Synthesis of Trisubstituted Tetrahydropyrans (1999) (80)
- Total synthesis of (+)-sieboldine A. (2010) (80)
- Facile aminolysis of epoxides with diethylaluminum amides (1981) (80)
- Enantioselective Total Synthesis of (-)-7-Deacetoxyalcyonin Acetate. First Synthesis of a Eunicellin Diterpene (1995) (79)
- Enantioselective total synthesis of (+)-gliocladin C. (2007) (79)
- Synthesis studies directed toward gelsemine. Preparation of an advanced pentacyclic intermediate (1988) (79)
- Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction. (2006) (78)
- H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus (2016) (78)
- Iminium ion and acyliminium ion initiated cyclization reactions of vinylsilanes. Regiocontrolled synthesis of tetrahydropyridines and related heterocycles (1987) (76)
- General approach to halogenated tetrahydrofuran natural products from red algae of the genus Laurencia. Total synthesis of (±)-kumausallene and (±)-1-epi-kumausallene (1993) (75)
- Enantiospecific total synthesis of dendrobatid toxin 251D. A short chiral entry to the cardiac-active pumiliotoxin A alkaloids via stereospecific iminium ion-vinylsilane cyclizations (1981) (74)
- Palladium-catalyzed, polyene cyclizations (1992) (74)
- Palladium catalyzed enantioselective rearrangement of allylic imidates to allylic amides (1999) (71)
- Total synthesis of (-)-sarain A. (2007) (71)
- Fragment Coupling and the Construction of Quaternary Carbons Using Tertiary Radicals Generated From tert-Alkyl N-Phthalimidoyl Oxalates By Visible-Light Photocatalysis. (2015) (71)
- Total synthesis of asperazine. (2001) (70)
- Total synthesis of (+/-)-didehydrostemofoline (asparagamine A) and (+/-)-isodidehydrostemofoline. (2003) (70)
- Constructing quaternary stereogenic centers using tertiary organocuprates and tertiary radicals. Total synthesis of trans-clerodane natural products. (2015) (70)
- Scope and facial selectivity of the Prins-pinacol synthesis of attached rings. (2006) (70)
- A general strategy for the synthesis of cladiellin diterpenes: enantioselective total syntheses of 6-acetoxycladiell-7(16),11-dien-3-ol (deacetoxyalcyonin acetate), cladiell-11-ene-3,6,7-triol, sclerophytin A, and the initially purported structure of sclerophytin A. (2001) (70)
- Enantioselective total syntheses of pumiliotoxin B and pumiliotoxin 251D. A general entry to the pumiliotoxin A alkaloids via stereospecific iminium ion-vinylsilane cyclizations (1984) (69)
- Synthesis of tert-Leucine-Derived Cobalt Oxazoline Palladacycles. Reversal of Palladation Diastereoselectivity and Application to the Asymmetric Rearrangement of N-Aryl Trifluoroacetimidates (2005) (69)
- Asymmetric Heck Reactions via Neutral Intermediates: Enhanced Enantioselectivity with Halide Additives Gives Mechanistic Insights (1997) (68)
- General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A. (2013) (68)
- Enantioselective total synthesis of guanacastepene N using an uncommon 7-endo Heck cyclization as a pivotal step. (2006) (67)
- THE FIRST SELECTIVE ANTAGONIST FOR A GABAC RECEPTOR (1996) (67)
- Catalytic asymmetric synthesis of allylic aryl ethers. (2007) (66)
- Stereocontrolled Synthesis of the Tetracyclic Core of the Bisguanidine Alkaloids Palau'amine and Styloguanidine (1997) (66)
- Nucleophilic cleavage of the sulfur-sulfur bond by phosphorus nucleophiles. IV. Kinetic study of the reduction of alkyl disulfides with triphenylphosphine and water (1974) (65)
- Synthetic applications of N-acylamino-1,3-dienes. 10. Importance of allylic interactions and stereoelectronic effects in dictating the steric course of the reaction of iminium ions with nucleophiles. An efficient total synthesis of (.+-.)-gephyrotoxin (1983) (65)
- Forging C(sp3)-C(sp3) Bonds with Carbon-Centered Radicals in the Synthesis of Complex Molecules. (2018) (65)
- Enantioselective total synthesis of batzelladine F: structural revision and stereochemical definition. (2001) (64)
- Total synthesis of (±)-scopadulcic acid A. An illustration of the utility of palladium-catalyzed polyene cyclizations (1993) (62)
- Catalyzed sigmatropic rearrangements. 5. Palladium(II) chloride catalyzed Cope rearrangements of acyclic 1,5-dienes (1980) (62)
- Total syntheses of (+)-geissoschizine, (.+-.)-geissoschizine, and (.+-.)-(Z)-isositsirikine. Stereocontrolled synthesis of exocyclic double bonds by stereospecific iminium ion-vinylsilane cyclizations (1989) (62)
- The first enantioselective total syntheses of the allopumiliotoxin A alkaloids 267A and 339B (1992) (61)
- trans-1-N-Acylamino-1,3-dienes: preparation from dienoic acids (1978) (60)
- Synthesis applications of cationic aza-Cope rearrangements. 24. The aza-Cope-Mannich approach to Strychnos alkaloids. Short stereocontrolled total syntheses of (.+-.)-dehydrotubifoline and (.+-.)-akuammicine (1993) (59)
- Controlling stereoselection in intramolecular heck reactions by tailoring the palladium catalyst (1992) (59)
- Cyclopalladated ferrocenyl amines as enantioselective catalysts for the rearrangement of allylic imidates to allylic amides (1997) (59)
- Enantioselective Total Synthesis of Either Enantiomer of the Antifungal Antibiotic Preussin (L-657,398) from (S)-Phenylalanine (1994) (59)
- Nucleophile-promoted electrophilic cyclization reactions of alkynes (1988) (59)
- Synthetic applications of N-acylamino-1,3-dienes. An efficient stereospecific total synthesis of dl-pumiliotoxin C, and a general entry to cis-decahydroquinoline alkaloids (1978) (58)
- Application of the Tethered Biginelli Reaction for Enantioselective Synthesis of Batzelladine Alkaloids. Absolute Configuration of the Tricyclic Guanidine Portion of Batzelladine B. (1999) (58)
- Preparation of eight-membered cyclic ethers by Lewis acid promoted acetal-alkene cyclizations (1990) (56)
- Enantioselective total synthesis of the cyclotryptamine alkaloid idiospermuline. (2003) (56)
- Palladium (II) - catalyzed rearrangement of allylic acetates (1979) (56)
- A convenient method for obtaining trans-2-aminocyclohexanol and trans-2-aminocyclopentanol in enantiomerically pure form (1985) (56)
- Enantioselective total synthesis of shahamin K. (2001) (56)
- Acetal-initiated cyclizations of vinylsilanes. A general synthesis of allylically unsaturated oxacyclics (1986) (56)
- Carbon-carbon bond formation via directed 2-azonia-[3,3]-sigmatropic rearrangements. A new pyrrolidine synthesis (1979) (54)
- Studies towards the total synthesis of palau'amine. Formation of 4,5-dihydropyrrole-2-carboxylate intermediates by alkene–enamide ring-closing metathesis (2004) (54)
- Chair topology of the palladium dichloride catalyzed Cope rearrangement of acyclic 1,5-dienes (1982) (54)
- On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis. (2007) (54)
- Enantioselective total synthesis of briarellins E and F: the first total syntheses of briarellin diterpenes. (2003) (54)
- Asymmetric construction of rings A-D of daphnicyclidin-type alkaloids. (2009) (53)
- Stereocontrolled preparation of tetrahydrofurans from acid-promoted rearrangements of allylic acetals (1991) (52)
- Synthesis of substituted tetrahydropyridines by cyclizations of silicon-containing iminium ions (1988) (52)
- Formation of .DELTA.4-oxocenes from Lewis acid promoted cyclizations of 5-hexenyl acetals. Evidence for a concerted ene cyclization mechanism (1990) (52)
- Total Syntheses of Pumiliotoxin A and Allopumiliotoxin Alkaloids. Interplay of Pharmacologically Active Natural Products and New Synthetic Methods and Strategies. (1996) (52)
- Mild procedures for interconverting allylic oxygen functionality. Cyclization-induced [3,3] sigmatropic rearrangement of allylic carbamates (1978) (51)
- A convenient synthesis of 4-unsubstituted .beta.-lactams (1985) (51)
- Synthesis applications of cationic aza-Cope rearrangements. Part 18. Scope and mechanism of tandem cationic aza-Cope rearrangement-Mannich cyclization reactions (1988) (51)
- Intramolecular N-(acyloxy)iminium ion-alkyne cycloadditions. A new route to bicyclic .alpha.-amino ketones (1990) (51)
- Complementary use of iminium ion and N-acyl iminium ion cyclization initiators for asymmetric synthesis of both enantiomers of hydroxylated indolizidines (1989) (51)
- Total Synthesis of (+)-Isolaurepinnacin. Use of Acetal-Alkene Cyclizations To Prepare Highly Functionalized Seven-Membered Cyclic Ethers (1997) (50)
- A Practical Entry to the Crambescidin Family of Guanidine Alkaloids. Enantioselective Total Syntheses of Ptilomycalin A, Crambescidin 657 and Its Methyl Ester (Neofolitispates 2), and Crambescidin 800 (2000) (50)
- Synthesis of trichloroacetamido-1,3-dienes. Useful aminobutadiene equivalents for the Diels-Alder reaction (1976) (50)
- General approach to halogenated tetrahydrofuran natural products from red algae of the genus Laurencia. Total synthesis of (.+-.)-trans-kumausyne and demonstration of an asymmetric synthesis strategy (1991) (50)
- Synthesis applications of aza-Cope rearrangements. 12. Applications of cationic aza-Cope rearrangements for alkaloid synthesis. Stereoselective preparation of cis-3a-aryloctahydroindoles and a new short route to Amaryllidaceae alkaloids (1983) (50)
- Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck. (2004) (49)
- Mechanism of the cobalt oxazoline palladacycle (COP)-catalyzed asymmetric synthesis of allylic esters. (2010) (49)
- Synthesis applications of aza-Cope rearrangements. 11. Carbon-carbon bond formation under mild conditions via tandem cationic aza-Cope rearrangement-Mannich reactions. A convenient synthesis of polysubstituted pyrrolidines (1983) (49)
- Enantioselective synthesis of (−)-idiospermuline (2003) (49)
- New approach to Strychnos alkaloids. Stereocontrolled total synthesis of (.+-.)-dehydrotubifoline (1991) (49)
- Synthesis applications of cationic aza-Cope rearrangements. Part 25. Total synthesis of Amaryllidaceae alkaloids of the 5,11-methanomorphanthridine type. Efficient total syntheses of (-)-pancracine and (.+-.)-pancracine (1993) (48)
- Enantioselective total syntheses of the cyclotryptamine alkaloids hodgkinsine and hodgkinsine B. (2003) (48)
- Total synthesis of (+)-nankakurines A and B and (±)-5-epi-nankakurine A. (2010) (48)
- Efficient Total Syntheses of Pumiliotoxins A and B. Applications of Iodide-Promoted Iminium Ion−Alkyne Cyclizations in Alkaloid Construction (1996) (48)
- Catalyzed sigmatropic rearrangements. 10. Mechanism of the palladium dichloride catalyzed Cope rearrangement of acyclic dienes. A substituent effect study (1990) (47)
- Diels-Alder reactions between trans-1-N-acylamino-1,3-dienes and methyl acrylate. A correlation between diene photoelectron ionization potentials and reactivity, stereoselectivity, and regioselectivity (1978) (47)
- Aza-cope rearrangement-mannich cyclizations for the formation of complex tricyclic amines: stereocontrolled total synthesis of (+/-)-gelsemine. (2005) (46)
- Palladium(II)-catalyzed enantioselective synthesis of 2-vinyl oxygen heterocycles. (2012) (46)
- An unexpected product arising from metal alkylidene mediated ring-closing diene metathesis (1997) (46)
- Mannich Biscyclizations. Total Synthesis of (-)-Ajmalicine (1995) (46)
- Total Synthesis of (−)-Crinine. Use of Tandem Cationic Aza-Cope Rearrangement/Mannich Cyclizations for the Synthesis of Enantiomerically Pure Amaryllidaceae Alkaloids†‡ (1985) (46)
- Diels-Alder reactions of 1-(acylamino)-1,3-dienes (1981) (46)
- Molecular Rearrangements in the Construction of Complex Molecules. (2009) (46)
- A Suzuki Coupling Method for Directly Introducing a Protected β-Aminoethyl Group into Arenes and Alkenes. Convenient Synthesis of Phenethyl and Homoallylic Amines (1999) (46)
- Catalytic asymmetric intramolecular aminopalladation: improved palladium(II) catalysts. (2005) (45)
- Construction of epidithiodioxopiperazines by directed oxidation of hydroxyproline-derived dioxopiperazines. (2007) (44)
- Generation of the Methoxycarbonyl Radical by Visible-Light Photoredox Catalysis and Its Conjugate Addition with Electron-Deficient Olefins. (2016) (44)
- Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes (2019) (43)
- Total synthesis of (+)-sarain A. (2006) (43)
- Acid-promoted reaction of cyclic allylic diols with carbonyl compounds. Stereoselective ring-enlarging tetrahydrofuran annulations (1991) (42)
- Preparation and Diels-Alder reactions of 1,3-dienes containing both sulfur and nitrogen substituents. Complete orientational control by the acylamino group (1983) (42)
- The Allylic Trihaloacetimidate Rearrangement (2005) (42)
- Synthesis applications of aza-Cope rearrangements. Part 10. A new approach for the total synthesis of pentacyclic Aspidosperma alkaloids. Total synthesis of dl-16-methoxytabersonine (1983) (41)
- Thwarting β-Hydride Elimination: Capture of the Alkylpalladium Intermediate of an Asymmetric Intramolecular Heck Reaction. (2001) (41)
- Stereocontrolled construction of carbocyclic rings by sequential cationic cyclization-pinacol rearrangements (1989) (41)
- Stereocontrolled synthesis of triazacyclopenta[cd]pentalenes by intramolecular 1,3-dipolar cycloaddition reactions of azomethine imines. (2002) (41)
- Stereoselective total synthesis of (.+-.)-perhydrogephyrotoxin. Synthetic applications of directed 2-azonia-[3,3]-sigmatropic rearrangements (1980) (41)
- Total synthesis of the supposed structure of (-)-sclerophytin A and an improved route to (-)-7-deacetoxyalcyonin acetate. (2000) (41)
- Total Synthesis of (±)-Scopadulcic Acid B (1997) (40)
- Enantioselective total synthesis of batzelladine F and definition of its structure. (2006) (40)
- Total synthesis of (+)-sieboldine a: evolution of a pinacol-terminated cyclization strategy. (2013) (40)
- Efficient preparations of 8- and 9-membered cyclic ethers (1986) (39)
- Thermal rearrangements of propargylic trichloroacetimidates. Synthesis of (trichloroacetamido)-1,3-dienes and -1,2-dienes (1981) (39)
- Chemical behavior of o-bis(phenylethynyl)benzene toward some electrophilic and nucleophilic reagents (1969) (39)
- Iminium ion and acyl iminium ion initiated cyclizations of vinylsilanes. Regiocontrolled construction of unsaturated azacyclics (1983) (39)
- Enantioselective total synthesis of (+)-pumiliotoxin A (1985) (39)
- Studies toward the total synthesis of (+)-ptilomycalin A. Use of a tethered Biginelli condensation for the preparation of an advanced tricyclic intermediate (1993) (38)
- Total Synthesis of (-)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade. (2018) (38)
- Planar-chiral cyclopalladated ferrocenyl amines and imines as enantioselective catalysts for allylic imidate rearrangements (1998) (38)
- Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis. (2021) (38)
- Asymmetric total synthesis of batzelladine D. (1999) (37)
- Golgi-modifying properties of macfarlandin E and the synthesis and evaluation of its 2,7-dioxabicyclo[3.2.1]octan-3-one core (2010) (37)
- Diastereoselection in the formation of spirocyclic oxindoles by the intramolecular Heck reaction. (2006) (37)
- Preparation of seven-membered ring cyclic ethers and 3-alkylidenetetrahydropyrans from the cyclization of oxonium cations derived from unsubstituted and silicon-containing 4-alken-1-ols (1989) (37)
- Inhibition of HIV-1 envelope-mediated fusion by synthetic batzelladine analogues. (2004) (37)
- Versatile Construction of 6-Substituted cis-2,8-Dioxabicyclo[3.3.0]octan-3-ones: Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C. (2017) (37)
- Stereocontrolled preparation of tetrahydrofurans by acid-catalyzed rearrangement of allylic acetals (1987) (36)
- Enantioselective total synthesis of (+)-isolaurepinnacin (1993) (36)
- Synthesis applications of cationic aza-Cope rearrangements. 20. Total synthesis of (.+-.)-meloscine and (.+-.)-epimeloscine (1989) (36)
- Short Enantioselective Total Syntheses of trans-Clerodane Diterpenoids: Convergent Fragment Coupling Using a trans-Decalin Tertiary Radical Generated from a Tertiary Alcohol Precursor. (2016) (36)
- Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration. (2008) (36)
- Synthesis applications of cationic aza-Cope rearrangements. 23. First total synthesis of amaryllidaceae alkaloids of the 5,11-methano morphanthridine type. An efficient total synthesis of (.+-.)-pancracine (1991) (36)
- An enantioselective approach to the synthesis of manzamine A (1994) (36)
- Enantioselective syntheses of authentic sclerophytin A, sclerophytin B, and cladiell-11-ene-3,6,7-triol. (2001) (36)
- New cationic olefin cyclization-pinacol reactions. Ring-expanding cyclopentane annulations that directly install useful functionality in the cyclopentane ring. (2002) (36)
- Facile Preparation of Spirolactones by an Alkoxycarbonyl Radical Cyclization-Cross-Coupling Cascade. (2019) (35)
- Highly stereocontrolled reduction of α′-alkoxyenones to give either the threo or eryhtro allylic 1,2-diol. Assignment of the threo configuration to the C-15, C-16 diol of pumiliotoxin B.1 (1982) (35)
- Stereoselection in the prins-pinacol synthesis of 2,2-disubstituted 4-acyltetrahydrofurans. Enantioselective synthesis of (-)-citreoviral. (2000) (35)
- Palladium(II)-Catalyzed Enantioselective Reactions Using COP Catalysts. (2016) (35)
- Enantioselective total synthesis of streptazolin. The tandem use of iminium ion vinylsilane cyclizations and intramolecular acylations (1987) (35)
- Synthesis of polycyclic guanidines by cyclocondensation reactions of N-amidinyliminium ions. (2001) (34)
- The Intramolecular Mannich and Related Reactions (1991) (34)
- tert-Butyldiphenylsilylamines: A useful protecting group for primary amines☆ (1986) (34)
- Evolution of a strategy for the synthesis of structurally complex batzelladine alkaloids. Enantioselective total synthesis of the proposed structure of batzelladine F and structural revision. (2006) (33)
- Enantioselective Total Synthesis of Hispidospermidin (1998) (33)
- Stereocontrolled synthesis of functionalized cis-cyclopentapyrazolidines by 1,3-dipolar cycloaddition reactions of azomethine imines. (2006) (33)
- Identification of an Unexpected 2-Oxonia[3,3]sigmatropic Rearrangement/Aldol Pathway in the Formation of Oxacyclic Rings. Total Synthesis of (+)-Aspergillin PZ. (2011) (33)
- Total Synthesis of (-)-Chromodorolide B. (2016) (33)
- PREPARATION OF SUBSTITUTED 2-PYRIDONES BY THERMAL REARRANGEMENT OF PROPARGYLIC PYRROLIDINE PSEUDOUREAS (1980) (33)
- Synthesis of 2-Azatricyclo[5.2.1.0(4,10)]decanes and 2,5-Diazatricyclo[5.2.1.0(4,10)]decanes by Intramolecular Azomethine Ylide Cycloadditions. (1996) (33)
- Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)-Allylic Alcohols. (2009) (33)
- Enantioselective Total Syntheses of Allopumiliotoxins 267A, 323B‘, and 339A. Application of Iodide-Promoted Iminium Ion−Alkyne Cyclizations for Forming Allopumiliotoxin A Alkaloids (1996) (32)
- Preparation of opium alkaloids by palladium catalyzed bis-cyclizations. Formal total synthesis of morphine (1994) (32)
- Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C via Convergent Fragment Coupling Using a Tertiary Carbon Radical. (2017) (32)
- ENANTIOSELECTIVE TOTAL SYNTHESIS OF ALLOPUMILIOTOXIN A ALKALOIDS 267A AND 339B (1984) (32)
- Tuning Stereoselection in Tethered Biginelli Condensations. Synthesis of cis- or trans-1-Oxo- and 1-Iminohexahydropyrrolo[1,2-c]pyrimidines. (1999) (32)
- First total synthesis of (+)-allopumiliotoxin 339A. A practical entry to dendrobatid alkaloids of the allopumiliotoxin class (1992) (32)
- Hemiacetal mediated reactions. Directed synthesis of diols and acetals (1974) (31)
- Application of intramolecular Heck reactions to the preparation of steroid and terpene intermediates having cis A-B ring fusions. Model studies for the total synthesis of complex cardenolides. (1994) (31)
- The Reduction of Aryl Disulfides with Triphenylphosphine and Water (1974) (31)
- Absolute configuration of actinophyllic acid as determined through chiroptical data. (2009) (31)
- Total synthesis and properties of the crambescidin core zwitterionic acid and crambescidin 359. (2005) (30)
- Enantioselective synthesis of six-membered palladacycles having metal-bound stereogenic carbons: isolation and reactivity of palladacycles containing readily accessible beta-hydrogens. (2004) (29)
- HALIDE-TERMINATED N-ACYLIMINIUM ION-ALKYNE CYCLIZATIONS: A NEW CONSTRUCTION OF CARBACEPHEM ANTIBIOTICS (1997) (29)
- Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activity. (2007) (29)
- Synthesis applications of cationic aza-Cope rearrangements. Part 17. Transition-state geometry of [3,3]-sigmatropic rearrangements of iminium ions (1988) (29)
- Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space (2018) (29)
- Pumiliotoxin alkaloids: a new class of sodium channel agents. (1990) (29)
- Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes. (2016) (29)
- The importance of vinylsilane stereochemistry and σ - π stabilization in iminium ion-vinylsilane cyclizations. A short total synthesis of the alkaloid (−) −epielwesine. (1984) (28)
- Synthesis and Diels-Alder reactions of 5-alkenyl-1,3-oxathiole 3-oxides. A new class of diheterosubstituted 1,3-dienes (1988) (28)
- Synthesis and anticancer activity of side chain analogs of the crambescidin alkaloids. (2004) (28)
- Stereocontrolled synthesis of substituted cis-cyclopenta[b]pyrrolidines (1985) (28)
- Enantioselective total synthesis of aplyviolene. (2011) (28)
- A Strategy for Total Synthesis of Complex Cardenolides. (1996) (28)
- A new asymmetric synthesis of trans-hydroisoquinolones. (2001) (27)
- A new strategy for synthesis of attached rings (2000) (27)
- Enantioselective total synthesis of plectosphaeroic acid B. (2013) (27)
- Enantioselective total synthesis of the pumiliotoxin A alkaloids via reductive iminium ion-alkyne cyclizations. Total synthesis of (+)-pumiliotoxin A (1988) (27)
- Synthesis applications of aza-Cope rearrangements. Stereoselective synthesis of cis-3a-aryloctahydroindoles and a new short entry to Amaryllidaceae alkaloids (1981) (27)
- A versatile synthesis of unsymmetrical 3,3'-bioxindoles: stereoselective Mukaiyama aldol reactions of 2-siloxyindoles with isatins. (2008) (27)
- A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid A new class of A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid pumiliotoxin B (8-hydroxy-8-methyl-6-alkylidene (1985) (27)
- Stereocontrolled construction of either stereoisomer of 12-oxatricyclo[6.3.1.0(2,7)]dodecanes using Prins-pinacol reactions. (2004) (26)
- Carbonyl participation in the reaction of N-acyl-2-isopropenylpyrrolidines with halogen electrophiles. Stereocontrolled preparation of enantiomerically pure synthons for the synthesis of pumiliotoxin A alkaloids. (1982) (26)
- A New Method for Stereocontrolled Synthesis of Substituted Tetrahydrothiophenes (2000) (26)
- Preparation of functionalized hydroindol-3-ols via tandem aza-Cope rearrangement-Mannich cyclizations. Formal total synthesis of (±)-6a-epipretazettine and related alkaloids (1989) (26)
- Preparation of enantioenriched tetrahydropyridines by iminium ion-vinylsilane cyclizations (1993) (26)
- A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment. (2009) (25)
- Investigation of a dialkylation approach for enantioselective construction of vicinal quaternary stereocenters. (2000) (25)
- Ring-enlarging furan annulations (1987) (25)
- Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes. (2011) (25)
- Asymmetric Construction of the Diazatricyclic Core of the Marine Alkaloids Sarains A−C (1998) (25)
- Enantioselective synthesis of angularly substituted 1-azabicyclic ring systems: dynamic kinetic resolution using aza-Cope rearrangements. (2010) (25)
- Catalytic asymmetric synthesis of allylic thiol derivatives. (2008) (25)
- Total synthesis of (+)-condylocarpine, (+)-isocondylocarpine, and (+)-tubotaiwine. (2011) (24)
- Diastereoselection in the formation of contiguous quaternary carbon stereocenters by the intramolecular Heck reaction. (2006) (24)
- Regioselective opening of terminal epoxides with 2-(trialkylsilyl)allyl organometallic reagents (1994) (24)
- Aloperine: Stereocontrolled Synthesis of Two Stereoisomers and Determination of Absolute Configuration. (1997) (24)
- Stereoselection in the Prins-pinacol synthesis of acyltetrahydrofurans. (2001) (24)
- Nucleophilic cleavage of the sulfur-sulfur bond by phosphorus nucleophiles. III. Kinetic study of the reduction of a series of ethyl aryl disulfides with triphenylphosphine and water (1975) (24)
- Enantioselective synthesis of cardenolide precursors using an intramolecular Heck reaction (1998) (23)
- Medium effects and the nature of the rate-determining step in Mannich-type cyclizations (1987) (23)
- Intramolecular Heck cyclization of α-sulfenyl enol triflates. Asymmetric synthesis of a pentacyclic cardenolide precursor having functionality at C-11 (1998) (23)
- A short stereospecific total synthesis of dl-pumiliotoxin C (1977) (23)
- The cyanomethyl group for nitrogen protection and iminium ion generation in ring-enlarging pyrrolidine annulations. A short synthesis of the amaryllidaceae alkaloid d,1-crinine (1982) (23)
- Pumiliotoxin alkaloids: relationship of cardiotonic activity to sodium channel activity and phosphatidylinositol turnover. (1988) (23)
- STEREOCONTROLLED SYNTHESIS OF EXOCYCLIC TRISUBSTITUTED DOUBLE BONDS BY STEREOSPECIFIC IMINIUM ION-VINYLSILANE CYCLIZATIONS. A SHORT SYNTHETIC ROUTE TO INDOLOQUINOLIZIDINE ALKALOIDS (1982) (23)
- Construction of substituted cyclohexanones by reductive cyclization of 7-oxo-2,8-alkadienyl esters. (2002) (23)
- 1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis. (2018) (23)
- Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists. (1982) (22)
- Synthesis applications of cationic aza-Cope rearrangements. Stereocontrolled synthesis of hexahydro-1H-pyrrolo[2,3-d]carbazoles (1985) (22)
- Asymmetrische Heck‐Reaktionen über neutrale Intermediate: Verstärkung der Enantioselektion durch Halogenid‐Additive und Einblicke in den Mechanismus (1997) (21)
- N-acyl-1-amino-1,3-dienes: 1-amino-1,3-diene synthetic equivalents for the diels-alder reaction (1976) (20)
- Toward an enantioselective total synthesis of sarain A: construction of an advanced intermediate and rearrangement of the sarain A core under mild conditions. (2005) (20)
- Asymmetric construction of quaternary carbon stereocenters: high stereoselection in Mukaiyama aldol reactions of 2-siloxyindoles with chiral aldehydes. (2005) (20)
- Allylic Transposition of Alcohol and Amine Functionality by Thermal or Palladium(II)-Catalyzed Rearrangements of Allylic N-Benzoylbenzimidates. (1997) (20)
- Preparation of 3-amino-4-(hydroxymethyl)azetidin-2-ones from the reaction of glycine enolates with imines of a glycoaldehyde (1991) (20)
- Gas phase acidities of the 2-butenes. The use of organometallics as models for free carbanions (1977) (20)
- Synthesis of allopumiliotoxin A alkaloids via iminium ion-vinylsilane cyclizations (1988) (20)
- Synthesis applications of cationic aza-Cope rearrangements. Part 13. Stereoselective synthesis of cis- and trans-3a-aryl-4-oxodecahydrocyclohepta[b]pyrroles (1983) (20)
- Total synthesis of the reputed structure of alcyonin and reassignment of its structure. (2003) (19)
- A CONVENIENT SYNTHESIS OF UNSYMMETRICAL SECONDARY AMINES. IN SITU FORMATION OF UNSTABLE FORMALDEHYDE IMINES (1984) (19)
- Simple method for controlling stereoselection in Mannich cyclization reactions of aldehydes (1993) (19)
- Palladium dichloride catalyzed cope rearrangements of functionalized acyclic 1,5-dienes☆ (1983) (18)
- Synthesis applications of aza-cope rearrangements : A stereoselective synthesis of 9a-arylhydrolilolidines [and a new approach to the synthesis of aspidosperma] alkaloids (1981) (18)
- Total synthesis of (-)-crambidine and definition of the relative configuration of its unique tetracyclic guanidinium core. (2005) (18)
- Ring-enlarging cyclopentene annulations (1991) (18)
- Origin of stereocontrol in the construction of the 12-oxatricyclo[6.3.1.0(2,7)]dodecane ring system by Prins-pinacol reactions. (2010) (18)
- Mercury(II)-catalyzed 3,3-sigmatropic rearrangements of allylic N,N-dimethylcarbamates. A mild method for allylic equilibrations and contrathermodynamic allylic isomer enrichments (1976) (18)
- The synthesis of indolizidines by intramolecular ene cyclizations. Preparation of (E)-alkylidene analogs of pumiliotoxin A. (1985) (18)
- Synthesis of 2,5-Diaryl-1,5-dienes from Allylic Bromides Using Visible-Light Photoredox Catalysis. (2015) (17)
- Enantioselective synthesis of angularly substituted 1-azabicylic rings: coupled dynamic kinetic epimerization and chirality transfer. (2013) (17)
- Organic syntheses : an annual publication of satisfactory methods for the preparation of organic chemicals (1954) (17)
- Synthesis of 3-acyl-3-alkyloxindoles (1991) (17)
- Prins-pinacol spiroannulations (1997) (17)
- Reaction of Na2Fe(CO)4 with an unsaturated aziridinium ion. Unprecedented rearrangement of an alkyltetracarbonylferrate intermediate (1992) (17)
- Palladacyclic imidazoline-naphthalene complexes: synthesis and catalytic performance in Pd(II)-catalyzed enantioselective reactions of allylic trichloroacetimidates. (2012) (17)
- The First Selective Antagonist for a GABAC Receptor. (1996) (17)
- Tricyclic analogues of epidithiodioxopiperazine alkaloids with promising in vitro and in vivo antitumor activity (2015) (17)
- The Asymmetric Intramolecular Mizoroki–Heck Reaction in Natural Product Total Synthesis (2009) (16)
- Synthetic applications of N-(acylamino)-1,3-dienes. Control of endo stereoselectivity by the acyl substituent. Stereospecific synthesis of the analgesic Tilidine (1979) (16)
- The Asymmetric Intramolecular Heck Reaction in Natural Product Total Synthesis (2003) (16)
- EVALUATION OF STRATEGIES FOR THE SYNTHESIS OF THE GUANIDINE HEMIAMINAL PORTION OF PALAU'AMINE. (2006) (16)
- Forming tertiary organolithiums and organocuprates from nitrile precursors and their bimolecular reactions with carbon electrophiles to form quaternary carbon stereocenters. (2012) (15)
- Studies towards a total synthesis of sarains A-C. Stereospecific condensation of α,β-unsaturated esters with the phenyl oxazoline derivative of threonine (1999) (15)
- Enantioselective total syntheses of plectosphaeroic acids B and C. (2013) (15)
- Synthesis of 3-acyltetrahydrofurans from formaldehyde acetals of allylic diols † (2000) (15)
- Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids. (2015) (15)
- Synthesis studies directed toward gelsemine. A new synthesis of highly functionalized cis-hydroisoquinolines (1988) (15)
- Stereocontrolled synthesis of angularly substituted 1-azabicyclic rings by cationic 2-aza-cope rearrangements. (2005) (15)
- Enantioselective total synthesis of (-)-dehydrobatzelladine C. [structure: see text]. (2004) (14)
- A Convenient Method for the Preparation of 3-Substituted Glutarate Diesters (1994) (14)
- Assembling polycyclic bisguanidine motifs resembling batzelladine alkaloids by double tethered Biginelli condensations. (2003) (14)
- A NEW SYNTHESIS OF 2-PYRIDONES. SOLUTION THERMOLYSIS OF PROPARGYLIC PSEUDOUREAS (1977) (14)
- Origins of stereoselectivities of dihydroxylations of cis-bicyclo[3.3.0]octenes. (2012) (14)
- The preparation of N-trichloroacetamido-1,2-dienes (1979) (14)
- Totalsynthese von (±)‐Gelsemin (1999) (14)
- Stimuli-Responsive Dewetting/Wetting Smart Surfaces and Interfaces (2018) (13)
- Efficient Preparations of 8- and 9-Membered Cyclic Ethers. (1986) (13)
- Synthesis of 1-azaspiro[5.5]undec-7-en-2-one (1975) (13)
- Iodide-promoted aldiminium ion-alkyne cyclizations. A convenient synthesis of substituted tetrahydropyridines and 3-alkylidenepiperidines. (1992) (13)
- Introduction of the 2-(phenylthio)ethyl, 2-(phenylsulfinyl)ethyl, and 2,2-bis(phenylthio)ethyl substituents into cyclic ketones (1993) (13)
- Synthesis applications of aza-cope rearrangements. Stereoselective synthesis of trans-alkyl-cis-3a-aryloctahydroindolones.☆ (1982) (13)
- Ring-Enlarging Cyclohexane Annulations (1997) (12)
- Direct Stereo‐ and Enantiocontrolled Synthesis of Vicinal Stereogenic Quaternary Carbon Centers. Total Syntheses of meso‐ and (‐)‐Chimonanthine and (+)‐Calycanthine. (1999) (12)
- Preparation of rearranged allylic isocyanates from the reaction of allylic alkoxides with cyanogen chloride (1978) (12)
- 4-Methylene-4,5-dihydrooxazoles: isolation, properties, and use for the preparation of substituted oxazoles (1979) (12)
- Total Synrhesis of the Amaryllidaceae Alkaloid (±)-Epielwesine. The Importance of Vinylsilane Stereochemistry in Iminium Ion-Vinylsilane Cyclizations (1993) (11)
- Synthesis applications of aza-cope rearrangements.: Stereocontrolled synthesis of cyclohepta [b]pyroolidines1☆ (1982) (11)
- Synthesis applications of directed 2-azonia-[3,3]-sigmatropic rearrangements. 4. A new method for stereoselective piperidine annulation. Directing the 2-azonia-[3,3]-sigmatropic rearrangement by irreversible hydrolysis (1980) (11)
- Stereoselective synthesis of carbocyclic ring systems by pinacol-terminated Prins cyclizations (2002) (11)
- Diastereoselective lithiation of (eta6-arene)dicarbonyltriphenylphosphane chromium(0) oxazoline complexes--direct preparation of enantiopure complexes having planar chiral fragments of either configuration. (2002) (11)
- Investigations Directed at the Total Synthesis of Ouabain. Lessons Learned fromDegradation Studies (2000) (11)
- A convenient synthesis of Δ1-pyrrolines and Δ1- piperideines (1984) (11)
- Forming Cyclics with the Intramolecular Heck Reaction (1998) (10)
- Ligand-Controlled Diastereoselective 1,3-Dipolar Cycloadditions of Azomethine Ylides with Methacrylonitrile. (2015) (10)
- The Aza‐Cope/Mannich Reaction (2011) (10)
- How important is secondary overlap in determining the regioselectivity of Diels-Alder reactions? (1978) (10)
- The insulin secretory action of novel polycyclic guanidines: discovery through open innovation phenotypic screening, and exploration of structure-activity relationships. (2014) (10)
- Palladium dichloride-promoted cyclizations of 1,5-dienes. A new method for forming cyclohexenes. (1983) (9)
- APROTIC CHLORIDE AND BROMIDE-PROMOTED ALKYNE-IMINIUM ION CYCLIZATIONS (1996) (9)
- Preparation of substituted 2-pyridones by thermal rearrangement of propargylic pseudoureas. Improvements in the 2-pyridone yields by variations of the pseudourea NR2 substituent (1981) (9)
- Stereoselectivities of nucleophilic additions to cycloheptanones. Experimental and theoretical studies and general purpose force field for the prediction of nucleophilic addition stereoselectivities (1998) (9)
- Diastereoselective Coupling of Chiral Acetonide Trisubstituted Radicals with Alkenes. (2016) (9)
- Contiguous Stereogenic Quaternary Carbons: A Daunting Challenge in Natural Products Synthesis (2005) (9)
- Catalytic Enantioselective Synthesis of Quaternary Carbon Stereocenters (2020) (9)
- Pyridinomorphinans: Asymmetric synthesis of either enantiomer and opioid receptor binding selectivity (1997) (9)
- Enantioselective Total Synthesis of (-)-Ptilomycalin A. (1995) (9)
- Dehydrogenase enzyme models. Approximation of an alcohol and a pyridinium ring. (1972) (9)
- Catalytic asymmetric synthesis of chiral allylic esters. (2010) (9)
- NEW SYNTHETIC METHODS. (46). MERCURY(II)- AND PALLADIUM(II)-CATALYZED (3.3)-SIGMATROPIC REARRANGEMENTS (1984) (8)
- Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible-Light Irradiation of EDA Complexes. (2021) (8)
- NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia (2016) (8)
- Preparation of Spirocyclic Polyethers by Intramolecular Heck Reactions (1994) (8)
- Controlling Stereoselection in Aza-Cope-Mannich Reactions (1997) (8)
- A naturally occurring erythro diastereomer of pumiliotoxin b (1988) (8)
- Click Triazoles (2012) (7)
- Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Investigations of Intramolecular Heck Reactions of (E)‐α,β‐Unsaturated 2‐Haloanilides and Analogues to Form Enantioenriched Spirocyclic Products. (1998) (7)
- Solvolytic rearrangements accompanied by multiple alkyl shifts (1971) (7)
- Nucleophile-promoted electrophilic cyclization reactions of alkynes [Erratum to document cited in CA108(7):55853J] (1988) (7)
- Catalytic Asymmetric Synthesis of Quarternary Carbon Centers. Palladium-Catalyzed Formation of Either Enantiomer of Spirooxindoles and Related Spirocyclics Using a Single Enantiomer of a Chiral Diphosphine Ligand. (1993) (6)
- Directed 2-azonia-[3,3]-sigmatropic rearrangements. a convenient preparation of substituted 1-azaspiro[4,5]decanes (1979) (6)
- Preparation of (3S)-N,N-1,7-Bis-tert- butoxycarbonyl-3-hydroxyspermidine in High Enantiomeric Purity (1999) (6)
- Preparation of α-Sulfenyl Enones by Thermal Fragmentation of β-Sulfenyl Enol Triflates (2002) (6)
- New Synthetic Route to Perhydrohistorionicotoxin Using (3Z)-4-Butyl-3-trichloroacetamido-1,3-butadiene (1984) (6)
- Total Synthesis of (+)‐Aloperine. Use of a Nitrogen‐Bound Silicon Tether in an Intramolecular Diels—Alder Reaction. (1999) (6)
- Preparation of Unsaturated Seven and Eight Membered Nitrogen Heterocycles by Iodide-Promoted Alkyne-Iminium Ion Cyclizations (1992) (6)
- Enantioselective Total Synthesis of Macfarlandin C, a Spongian Diterpenoid Harboring a Concave-Substituted cis-Dioxabicyclo[3.3.0]octanone Fragment. (2020) (6)
- Intramolecular delivery of a water equivalent in the oxymercuration reaction. Conversion of an allylic alcohol into a cis- vicinal diol (1972) (6)
- Intramolecular Heck Reactions in Natural Product Chemistry (2007) (6)
- Preparation of (η5‐(S)‐2‐(4‐Methylethyl)‐Oxazolinylcyclopentadienyl)‐(η4‐Tetraphenylcyclo‐Butadiene)cobalt (2007) (6)
- Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer (2019) (5)
- Catalytic Asymmetric Synthesis of Quaternary Carbon Centers by Intramolecular Heck Reaction (2000) (5)
- The enantiomer of strychnine is a weak antagonist of the inhibitory glycine receptor (1995) (5)
- 1‐N‐Acylamino‐1,3‐dienes from 2,4‐Pentadienoic Acids by the Curtius Rearrangement: Benzyl trans‐1,3‐butadiene‐1‐carbamate (2003) (5)
- Use of Sequential Intramolecular Heck Cyclizations for Preparing Bicyclo[3.2.1]octane Fragments of Tetracyclic Stemodane and Stemarane Diterpenes (2001) (5)
- A NEW CLASS OF CARDIOTONIC AGENTS: STRUCTURE-ACTIVITY CORRELATIONS FOR NATURAL AND SYNTHETIC ANALOGS OF THE ALKALOID PUMILIOTOXIN (8-HYDROXY-8-METHYL-6-ALKYLIDENE-1-AZABICYCLO(4.3.0)NONANES) (1985) (5)
- Additions and Corrections - Synthesis of Trichloroacetamido-1,3-dienes. Useful Aminobutadiene Equivalents for the Diels-Alder Reaction (1976) (5)
- High Enantioselection in the Rearrangement of Allylic Imidates with Ferrocenyl Oxazoline Catalysts. (2010) (5)
- Preparation of Seven-Membered Cyclic Ethers Containing Halogenated Side Chains by Acetal-Alkene Cyclizations (2002) (5)
- Discussion Addendum for: Preparation of the COP Catalysts: [( S )‐COP‐OAc] 2 , [( S )‐COP‐Cl] 2 , and ( S )‐COP‐hfacac (2007) (4)
- Enantiodivergent Total Syntheses of (+)- and (-)-Scopadulcic Acid A. (1999) (4)
- Asymmetric Carbon–Carbon Bond‐Forming Reactions: Asymmetric Intramolecular Heck Reactions (2005) (4)
- The preparation of ureas by the thermolysis of allylic pseudoureas (1976) (4)
- Asymmetric Synthesis of Either Enantiomer of Opium Alkaloids and Morphinans. Total Synthesis of (‐)‐ and (+)‐Dihydrocodeinone and (‐)‐ and (+)‐Morphine. (1994) (4)
- Use of the Intramolecular Heck Reaction for Forming Congested Quaternary Carbon Stereocenters. Stereocontrolled Total Synthesis of (.+‐.)‐Gelsemine. (2006) (4)
- Correction to "Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling". (2016) (4)
- Regioselective Synthesis of Tetrahydropyridines: 1-(4-Methoxyphenyl)-1,2,5,6-tetrahydropyridine (2003) (3)
- CATIONIC CYCLIZATION REACTIONS TERMINATED BY PINACOL REARRANGEMENTS (1989) (3)
- Catalytic Asymmetric Synthesis of Quaternary Carbons Bearing Two Aryl Substituents. Enantioselective Synthesis of 3‐Alkyl‐3‐aryl Oxindoles by Catalytic Asymmetric Intramolecular Heck Reactions. (2003) (3)
- First Total Synthesis of Lycopodium Alkaloids of the Magellanane Group. Enantioselective Total Syntheses of (-)-Magellanine and (+)- Magellaninone. (1993) (3)
- Enantioselective Total Synthesis of the Kinesin Motor Protein Inhibitor Adociasulfate 1. (2000) (3)
- Synthesis of a Phenolic Analog of Aphidicolin. Diminished Stereoselection in Intramolecular 6-Exo Heck Reactions of Substrates Having a Hydrocarbon Tether (2000) (3)
- Enantioselective Total Syntheses of 13,14,15‐Isocrambescidin 800 and 13,14,15‐Isocrambescidin 657. (2000) (3)
- Intramolecular Alkene Arylations for Rapid Assembly of Polycyclic Systems Containing Quaternary Centers. A New Synthesis of Spirooxindoles and Other Fused and Bridged Ring Systems. (1988) (3)
- Enantioselective Total Synthesis of 13,14,15-Isocrambescidin 800 (I). (1999) (3)
- THERMAL AND MERCURIC ION CATALYZED (3,3)-SIGMATROPIC REARRANGEMENT OF ALLYLIC TRICHLORACETIMIDATES. THE 1,3 TRANSPOSITION OF ALCOHOL AND AMINE FUNCTIONS (1974) (3)
- Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)‐α,β‐Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates. (1998) (3)
- Visible‐Light Photocatalysis in the Synthesis of Natural Products (2018) (3)
- Fragment Coupling and Formation of Quaternary Carbons by Visible-Light Photoredox Catalyzed Reaction of tert -Alkyl Hemioxalate Salts and Michael Acceptors (2018) (3)
- Intramolecular Heck Cyclization of α‐Sulfenyl Enol Triflates. Asymmetric Synthesis of a Pentacyclic Cardenolide Precursor Having Functionality at C‐11. (1998) (2)
- Asymmetric Rearrangement of Allylic Trichloroacetimidates: Preparation of (S)‐2,2,2‐Trichloro‐N‐(1‐propylallyl)acetamide (2005) (2)
- Construction of Quaternary Carbon Centers by Palladium-Catalyzed Intramolecular Alkene Insertions. Total Synthesis of the Amaryllidaceae Alkaloids (.+-.)-Tazettine and (.+-.)-6a-Epipretazettine. (1990) (2)
- Studies Toward the Total Synthesis of (+)‐Ptilomycalin A. Use of a Tethered Biginelli Condensation for the Preparation of an Advanced Tricyclic Intermediate. (1993) (2)
- Catalytic Asymmetric Synthesis of Either Enantiomer of Physostigmine. Formation of Quaternary Carbon Centers with High Enantioselection by Intramolecular Heck Reactions of (Z)-2-Butenanilides. (1994) (2)
- Construction of Epidithiodioxopiperazines by Directed Oxidation of Hydroxyproline‐Derived Dioxopiperazines. (2008) (2)
- THE IMPORTANCE OF VINYLSILANE STEREOCHEMISTRY AND .SIGMA±PI. STABILIZATION IN IMINIUM ION-VINYLSILANE CYCLIZATIONS. A SHORT TOTAL SYNTHESIS OF THE AMARYLLIDACEAE ALKALOID (.+-.)-EPIELWESINE (1985) (2)
- Silyl ethers of cycloheptene, novel proton pump inhibitors obtained during the total synthesis of the scopadulcic acids (1995) (2)
- ENANTIOSELECTIVE TOTAL SYNTHESES OF PUMILIOTOXIN B AND PUMILIOTOXIN 251D. A GENERAL ENTRY TO THE PUMILIOTOXIN A ALKALOIDS VIA STEREOSPECIFIC IMINIUM ION‐VINYLSILANE CYCLIZATIONS (1984) (2)
- Total Synthesis of (.+-.)-Actinophyllic Acid. (2008) (2)
- Cluster Preface: StereoselectiveSynthesis of Stereogenic Quaternary Carbons: A FormidableChallenge and Remarkable Recent Progress (2010) (2)
- Enantioselective Total Synthesis of (+)‐Isolaurepinnacin. (1994) (2)
- DIELS‐ALDER REACTIONS BETWEEN TRANS‐1‐N‐ACYLAMINO‐1,3‐DIENES AND METHYL ACRYLATE. A CORRELATION BETWEEN DIENE PHOTOELECTRON IONIZATION POTENTIALS AND REACTIVITY, STEREOSELECTIVITY, AND REGIOSELECTIVITY (1978) (2)
- Enantioselective Total Synthesis of (-)-Dehydrobatzelladine C. (2004) (2)
- General Access to Concave-Substituted cis-Dioxabicyclo[3.3.0]octanones: Enantioselective Total Syntheses of Macfarlandin C and Dendrillolide A. (2020) (2)
- Synthesis of All Low‐Energy Stereoisomers of the Tris(pyrrolidinoindoline) Alkaloid Hodgkinsine and Preliminary Assessment of Their Antinociceptive Activity. (2008) (2)
- Stereocontrolled Preparation of Tetrahydrofurans from Acid‐Promoted Rearrangements of Allylic Acetals. (1991) (2)
- Total Synthesis of (.+‐.)‐Scopadulcic Acid B. (1998) (2)
- Erratum: Design and in vitro pharmacology of a selective γ-aminobutyric acidc receptor antagonist (Molecular Pharmacology (1996) 50 (1024-1030)) (2013) (2)
- Total Syntheses of Pumiliotoxin A and Allopumiliotoxin Alkaloids. Interplay of Pharmacologically Active Natural Products and New Synthetic Methods and Strategies (1996) (2)
- Synthesis of dihydroquinolinones angularly-fused to tetrahydrobenzazepinone rings (2006) (2)
- Enantioselective Construction of Vicinal Stereogenic Quaternary Centers by Dialkylation: Practical Total Syntheses of (+)‐ and meso‐Chimonanthine. (2000) (2)
- Correction to "Total Synthesis of (-)-Sarain A". (2018) (2)
- A New Strategy for Synthesis of Attached Rings. (2000) (2)
- A short total synthesis of (.+-.)-perhydrogephyrotoxin (1981) (2)
- Sequential Catalytic Asymmetric Heck—Iminium Ion Cyclization: Enantioselective Total Synthesis of the Strychnos Alkaloid Minfiensine. (2005) (2)
- Enantioselective Synthesis of Cardenolide Precursors Using an Intramolecular Heck Reaction. (1998) (2)
- Studies Towards the Total Synthesis of Palau′amine. Formation of 4,5‐Dihydropyrrole‐2‐carboxylate Intermediates by Alkene—Enamide Ring‐Closing Metathesis. (2005) (2)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 17. Transition-State Geometry of (3,3)-Sigmatropic Rearrangements of Iminium Ions. (1988) (2)
- Total Synthesis of the Amaryllidaceae Alkaloid (.+-.)-Epielwesine. The Importance of Vinylsilane Stereochemistry in Iminium Ion-Vinylsilane Cyclizations. (1993) (2)
- Stereocontrolled Construction of Carbocyclic Rings by Sequential Cationic Cyclization-Pinacol Rearrangements. (1989) (2)
- Stereocontrolled preparation of tetrahydrofurans from acid-promoted rearrangements of allylic acetals. [Erratum to document cited in CA115(13):135825m] (1992) (1)
- Stereocontrolled Synthesis of the Tetracyclic Core of the Bisguanidine Alkaloids Palau′amine and Styloguanidine. (1997) (1)
- Synthesis of 2‐Azatricyclo(5.2.1.04,10)decanes and 2,5‐Diazatricyclo(5. 2.1.04,10)decanes by Intramolecular Azomethine Ylide Cycloadditions. (1997) (1)
- General Approach to Halogenated Tetrahydrofuran Natural Products from Red Algae of the Genus Laurencia. Total Synthesis of (.+-.)-trans- Kumausyne and Demonstration of an Asymmetric Synthesis Strategy. (1991) (1)
- Total Synthesis of (.+-.)- and (-)-Actinophyllic Acid. (2010) (1)
- Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)‐Allylic Alcohols. (2010) (1)
- Total Synthesis of (+)-Isolaurepinnacin. Use of Acetal-Alkene Cyclizations to Prepare Highly Functionalized Seven-Membered Cyclic Ethers. (1997) (1)
- Organic Reactions, Volume 71 (2008) (1)
- SYNTHESIS APPLICATIONS OF AZA‐COPE REARRANGEMENTS. PART 14. TOTAL SYNTHESIS OF (‐)‐CRININE. USE OF TANDEM CATIONIC AZA‐COPE REARRANGEMENT/MANNICH CYCLIZATIONS FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE AMARYLLIDACEAE ALKALOIDS (1985) (1)
- SYNTHESIS APPLICATIONS OF AZA-COPE REARRANGEMENTS. 12. APPLICATIONS OF CATIONIC AZA-COPE REARRANGEMENTS FOR ALKALOID SYNTHESIS. STEREOSELECTIVE PREPARATION OF CIS-3A-ARYLOCTAHYDROINDOLES AND A NEW SHORT ROUTE TO AMARYLLIDACEAE ALKALOI (1984) (1)
- CATALYZED SIGMATROPIC REARRANGEMENTS. 4. PALLADIUM(II)-CATALYZED REARRANGEMENT OF ALLYLIC ACETATES (1979) (1)
- Stereocontrolled Total Syntheses of meso‐Chimonanthine (I) and meso‐ Calycanthine (II) via a Novel Samarium Mediated Reductive Dialkylation. (1996) (1)
- CATALYZED SIGMATROPIC REARRANGEMENTS. 8. PALLADIUM DICHLORIDE-CATALYZED COPE REARRANGEMENTS OF FUNCTIONALIZED ACYCLIC 1,5-DIENES (1983) (1)
- First Total Synthesis of (+)-Allopumiliotoxin 339A. A Practical Entry to Dendrobatid Alkaloids of the Allopumiliotoxin Class. (1992) (1)
- Enantioselective Synthesis of (-)-Idiospermuline. (2003) (1)
- Stereocontrolled Preparation of 3‐Acyltetrahydrofurans from Acid‐Promoted Rearrangements of Allylic Ketals: (2S,3S)‐3‐Acetyl‐8‐Carboethoxy‐2,3‐Dimethyl‐1‐Oxa‐8‐Azaspiro[4.5]Decane (2003) (1)
- Synthesis of (+)-Sieboldine A (2010) (1)
- Ring‐Enlarging Cyclohexane Annulations. (1998) (1)
- A CONVENIENT SYNTHESIS OF 4-UNSUBSTITUTED β-LACTAMS (1985) (1)
- Enantioselective Total Synthesis of (‐)‐7‐Deacetoxyalcyonin Acetate. First Synthesis of a Eunicellin Diterpene. (1996) (1)
- Construction of Substituted Cyclohexanones by Reductive Cyclization of 7‐Oxo‐2,8‐alkadienyl Esters. (2002) (1)
- Synthesis of (±)-Actinophyllic Acid (2008) (1)
- A Suzuki Coupling Method for Directly Introducing a Protected β‐Aminoethyl Group into Arenes and Alkenes. Convenient Synthesis of Phenethyl and Homoallylic Amines. (2000) (1)
- Total Synthesis of (+)-Laurencin. Use of Acetal-Vinyl Sulfide Cyclizations for Forming Highly Functionalized Eight-Membered Cyclic Ethers. (1995) (1)
- tert-Butyldiphenylsilylamines: A Useful Protecting Group for Primary Amines. (1987) (1)
- CATALYZED SIGMATROPIC REARRANGEMENTS. 6. CHAIR TOPOLOGY OF THE PALLADIUM DICHLORIDE CATALYZED COPE REARRANGEMENT OF ACYCLIC 1,5-DIENES (1983) (1)
- Modeling Chemical Reactivity. Part 1. Regioselectivity of Diels-Alder Cycloadditions of Electron-Rich Dienes with Electron-Deficient Dienophiles. (1987) (1)
- Formation of δ4-Oxocenes from Lewis Acid Promoted Cyclizations of 5-Hexenyl Acetals. Evidence for a Concerted Ene Cyclization Mechanism. (1990) (1)
- Catalyzed Sigmatropic Rearrangements. Part 10. Mechanism of the Palladium Dichloride Catalyzed Cope Rearrangement of Acyclic Dienes. A Substituent Effect Study. (1990) (1)
- Efficient Total Syntheses of Pumiliotoxins A and B. Applications of Iodide-Promoted Iminium Ion-Alkyne Cyclizations in Alkaloid Construction. (1997) (1)
- Palladium-Catalyzed Polyene Cyclizations of Dienyl Aryl Iodides. (1988) (1)
- Constructing Saturated Guanidinum Heterocycles by Cycloaddition of N-Amidinyliminium Ions with Indoles. (2021) (1)
- Complementary Use of Iminium Ion and N-Acyliminium Ion Cyclization Initiators for Asymmetric Synthesis of Both Enantiomers of Hydroxylated Indolizidines. (1989) (1)
- A SHORT TOTAL SYNTHESIS OF (.+‐.)‐PERHYDROGEPHYROTOXIN (1981) (1)
- Halide‐Terminated N‐Acyliminium Ion—Alkyne Cyclizations: A New Construction of Carbacephem Antibiotics. (1998) (1)
- Total Synthesis of the Strychnos Alkaloid (+)-Minfiensine: Tandem Enantioselective Intramolecular Heck—Iminium Ion Cyclization. (2008) (1)
- Synthesis Applications of Cationic Aza‐Cope Rearrangements. Part 16. Stereocontrolled Synthesis of Substituted cis‐Cyclopenta[b]pyrrolidines. (1985) (1)
- Enantioselective Total Synthesis of Streptazolin. The Tandem Use of Iminium Ion-Vinylsilane Cyclizations and Intramolecular Acylations. (1988) (1)
- Enantioselective Total Synthesis of Briarellins E (I) and F (II): The First Total Syntheses of Briarellin Diterpenes. (2003) (1)
- Mannich Biscyclizations. Total Synthesis of (‐)‐Ajmalicine. (1995) (1)
- Intramolecular N-(Acyloxy)iminium Ion-Alkyne Cycloadditions. A New Route to Bicyclic α-Amino Ketones. (1990) (1)
- Synthesis of (+)-Asperazine (2007) (1)
- A Versatile Synthesis of Unsymmetrical 3,3′‐Bioxindoles: Stereoselective Mukaiyama Aldol Reactions of 2‐Siloxyindoles with Isatins. (2009) (1)
- NUCLEOPHILIC CLEAVAGE OF THE SULFUR-SULFUR BOND BY PHOSPHORUS NUCLEOPHILES PART 3, KINETIC STUDY OF THE REDUCTION OF A SERIES OF ETHYL ARYL DISULFIDES WITH TRIPHENYLPHOSPHINE AND WATER (1975) (1)
- Stereocontrolled Synthesis of Trisubstituted Tetrahydropyrans. (1999) (1)
- Stereoselectivities of Nucleophilic Additions to Cycloheptanones. Experimental and Theoretical Studies and General Purpose Force Field for the Prediction of Nucleophilic Addition Stereoselectivities. (2010) (1)
- Synthesis of Briarellins E and F (2010) (1)
- Enantioselective Total Syntheses of Allopumiliotoxins 267A, 323B′, and 339A. Application of Iodide‐Promoted Iminium Ion‐Alkyne Cyclizations for Forming Allopumiliotoxin A Alkaloids. (1997) (1)
- (Z)‐4‐(Trimethylsilyl)‐3‐Buten‐1‐ol (2003) (1)
- Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma (2021) (1)
- Vinylsilane- and Allylsilane-Terminated Cyclization Reactions (1987) (0)
- Preparation of Seven‐Membered Cyclic Ethers Containing Halogenated Side Chains by Acetal ‐ Alkene Cyclizations. (1993) (0)
- Preparation of (3S)-N,N-1,7-Bis-tert-butoxycarbonyl-3-hydroxyspermidine in High Enantiomeric Purity. (2000) (0)
- Synthesis of 3-Acyltetrahydrofurans from Formaldehyde Acetals of Allylic Diols. (2001) (0)
- Comprar Organic Reactions, Volume 70 | Larry E. Overman | 9780470254530 | Wiley (2008) (0)
- A CONVENIENT SYNTHESIS OF Δ1-PYRROLINES AND Δ1-PIPERIDINES (1985) (0)
- Synthesis of Substituted Tetrahydropyridines by Cyclizations of Silicon-Containing Iminium Ions. (1988) (0)
- A General Strategy for the Synthesis of Cladiellin Diterpenes: Enantioselective Total Syntheses of 6-Acetoxycladiell-7(16),11-dien-3-ol (Deacetoxyalcyonin Acetate) (I), Cladiell-11-ene-3,6,7-triol (II), Sclerophytin A (III), and the Initially Purported Structure (IV) of Sclerophytin A. (2002) (0)
- Scope and Limitations of the Thionium Ion-Initiated Prins-Pinacol Synthesis of Carbocycles (2004) (0)
- Stereoselective Synthesis of Carbocyclic Ring Systems by Pinacol‐Terminated Prins Cyclizations. (2010) (0)
- Correction to "Total Synthesis of (-)-Chromodorolide B By a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade". (2019) (0)
- Preparation of 3‐Amino‐4‐(hydroxymethyl)azetidin‐2‐ones from the Reaction of Glycine Enolates with Imines of a Glycoaldehyde. (1991) (0)
- Palladium‐Catalyzed Polyene Cyclizations of Trienyl Triflates. (1990) (0)
- A New Method for Stereocontrolled Synthesis of Substituted Tetrahydrothiophenes. (2001) (0)
- Introduction of the 2-(Phenylthio)ethyl, 2-(Phenylsulfinyl)ethyl, and 2,2-Bis(phenylthio)ethyl Substituents into Cyclic Ketones. (1994) (0)
- Synthesis and Diels-Alder Reactions of 5-Alkenyl-1,3-oxathiole 3-Oxides. A New Class of Diheterosubstituted 1,3-Dienes. (1988) (0)
- Total Synthesis of (.+-.)-Scopadulcic Acid A. An Illustration of the Utility of Palladium-Catalyzed Polyene Cyclizations. (2010) (0)
- Synthesis and Anticancer Activity of Side Chain Analogues of the Crambescidin Alkaloids. (2004) (0)
- Synthesis of Nankakurines A and B (2009) (0)
- Stereocontrolled Preparation of Tetrahydrofurans by Acid-Catalyzed Rearrangement of Allylic Acetals. (1987) (0)
- SYNTHESIS OF 1-AZASPIRO(5,5)UNDEC-7-EN-2-ONE (1975) (0)
- Thwarting beta-Hydride Elimination: Capture of the Alkylpalladium Intermediate of an Asymmetric Intramolecular Heck Reaction This research was supported by the National Institutes of Health (grant GM-12389). M.O. thanks the Deutsche Forschungsgemeinschaft (DFG) for an Emmy Noether fellowship (Oe 249 (2001) (0)
- Comprar Organic Reactions, Volume 68 | Organic Reactions, Inc. | 9780470098981 | Wiley (2007) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 25. Total Synthesis of Amaryllidaceae Alkaloids of the 5,11- Methanomorphanthridine Type. Efficient Total Synthesis of (-)- Pancracine (-)-(I) and (.+-.)-Pancracine. (1993) (0)
- A Publication of Reliable Methods for the Preparation of Organic Compounds (2017) (0)
- Allylically Transposed Amines from Allylic Alcohols: 3,7‐Dimethyl‐1,6‐Octadien‐3‐Amine (2003) (0)
- Synthesis of Dihydroquinolinones Angularly-Fused to Tetrahydrobenzazepinone Rings. (2006) (0)
- Preparation of alpha-sulfenyl enones by thermal fragmentation of beta-sulfenyl enol triflates. (2002) (0)
- Enantioselective Total Synthesis of (+)-Pumiliotoxin A. (1986) (0)
- Asymmetric Heck Reactions via Neutral Intermediates: Enhanced Enantioselectivity with Halide Additives Gives Mechanistic Insights. (1997) (0)
- A convinient synthesis of δ1-pyrolines and δ1-piperideines (1985) (0)
- Controlling Stereoselection in Aza‐Cope‐Mannich Reactions (1997) (0)
- Total Synthesis of Complex Cyclotryptamine Alkaloids: Stereocontrolled Construction of Quaternary Carbon Stereocenters (2007) (0)
- Synthesis Applications of Cationic Aza‐Cope Rearrangements. Part 27. Enantioselective Total Synthesis of Either Enantiomer of the Antifungal Antibiotic Preussin (L‐657,398) from (S)‐Phenylalanine. (1995) (0)
- Use of Sequential Intramolecular Heck Cyclizations for Preparing Bicyclo[3.2.1]octane Fragments of Tetracyclic Stemodane and Stemarane Diterpenes. (2001) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 24. Aza-Cope-Mannich Approach to Strychnos Alkaloids. Short Stereocontrolled Total Syntheses of (.+-.)-Dehydrotubifoline and (.+-.) -Akuammicine. (1993) (0)
- Palladium-Catalyzed Enantioselective Synthesis of Allylic Thiol Derivatives (2008) (0)
- Preparation of Unsaturated Seven‐ and Eight‐Membered Nitrogen Heterocycles by Iodide‐Promoted Alkyne‐Iminium Ion Cyclization. (1993) (0)
- Preparation of Spirocyclic Polyethers by Intramolecular Heck Reactions. (1995) (0)
- Correction: Lin et al. Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma. Cancers 2021, 13, 3367 (2021) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangement. Part 24. First Total Synthesis of Amaryllidaceae Alkaloids of the 5,11- Methanomorphanthridine Type. An Efficient Total Synthesis of (.+-.)- Pancracine (I). (1992) (0)
- Asymmetric Intramolecular Heck Reactions (2001) (0)
- A Convenient Method for Obtaining trans-2-Aminocyclohexanol and trans-2- Amino-cyclopentanol in Enantiomerically Pure Forms. (1986) (0)
- N-ACYL-1-AMINO-1,3-DIENES- 1-AMINO-1,3-DIENE SYNTHETIC EQUIVALENTS FOR THE DIELS-ALDER REACTION (1976) (0)
- Total Synthesis of (.+-.)-Didehydrostemofoline (I) (Asparagamine A) and (.+-.)-Isodidehydrostemofoline (II). (2004) (0)
- Scope and Limitations of the Thionium Ion-Initiated Prins—Pinacol Synthesis of Carbocycles. (2004) (0)
- Catalytic Asymmetric Synthesis of Quaternary Carbon Centers by Intramolecular Heck Reaction: Synthetic Developments and Mechanistic Studies (2001) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 22. New Approach to Strychnos Alkaloids. Stereocontrolled Total Synthesis of (.+-.)-Dehydrotubifoline. (1991) (0)
- Comprar Organic Reactions, Volume 71 | Larry E. Overman | 9780470098998 | Wiley (2008) (0)
- Synthesis of Guanacastepene N (2007) (0)
- Regioselective Opening of Terminal Epoxides with 2-(Trialkylsilyl) allyl Organometallic Reagents. (1995) (0)
- DIRECTED 2-AZONIA-(3,3)-SIGMATROPIC REARRANGEMENTS. A CONVENIENT PREPARATION OF SUBSTITUTED 1-AZASPIRO(4,5)DECANES (1980) (0)
- Controlling Stereoselection in Intramolecular Heck Reactions by Tailoring the Palladium Catalyst. (1993) (0)
- SYNTHESIS APPLICATIONS OF AZA-COPE REARRANGEMENTS. PART 7. STEREOSELECTIVE SYNTHESIS OF TRANS-2-ALKYL-CIS-3A-ARYLOCTAHYDROINDOLONES (1982) (0)
- An Unexpected Product Arising from Metal Alkylidene Mediated Ring-Closing Diene Metathesis. (1998) (0)
- Synthesis of (±)-Gelsemine (2006) (0)
- Enantioselective Total Synthesis of Hispidospermidin. (1998) (0)
- Stereocontrolled Synthesis of Angularly Substituted 1‐Azabicyclic Rings by Cationic 2‐Aza‐Cope Rearrangements. (2005) (0)
- Application of Intramolecular Heck Reactions to the Preparation of Steroid and Terpene Intermediates Having cis A‐B Ring Fusions. Model Studies for the Total Synthesis of Complex Cardenolides. (1994) (0)
- Asymmetric Construction of the Diazatricyclic Core of the Marine Alkaloids Sarains A—C. (1999) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 28. Asymmetric Total Syntheses of (-)- and (+)-Strychnine (IX) and the Wieland-Gumlich Aldehyde (VII). (1995) (0)
- Synthesis of (+)-Gliocladin C (2007) (0)
- Corrigendum: A Concise Synthesis of (−)‐Aplyviolene Facilitated by a Strategic Tertiary Radical Conjugate Addition (2014) (0)
- Planar-Chiral Cyclopalladated Ferrocenyl Amines and Imines as Enantioselective Catalysts for Allylic Imidate Rearrangements. (1999) (0)
- Heterocyclization reaction employing vinylsilane terminators (1985) (0)
- HIGHLY STEREOCONTROLLED REDUCTION OF α′-ALKOXYENONES TO GIVE EITHER THE THREO OR ERYTHRO ALLYLIC 1,2-DIOL. ASSIGNMENT OF THE THREO CONFIGURATION TO THE C-15,C-16 DIOL OF PUMILIOTOXIN B (1982) (0)
- Enantioselective Allylic Etherification Using a Novel COPCatalyst (2010) (0)
- Preparation of Enantioenriched Tetrahydropyridines by Iminium Ion‐ Vinylsilane Cyclizations. (1993) (0)
- An Enantioselective Approach to the Synthesis of Manzamine A. (1994) (0)
- Enantioselective Total Syntheses of Plectosphaeroic Acids B (Ia) and C (Ib). (2014) (0)
- First Enantioselective Catalyst for the Rearrangement of Allylic Imidates to Allylic Amides. (1997) (0)
- Synthesis Studies Directed Toward Gelsemine. A New Synthesis of Highly Functionalized cis-Hydroisoquinolines. (1989) (0)
- Enantioselective Syntheses of Authentic Sclerophytin A (Ia), Sclerophytin B (Ib), and Cladiell‐11‐ene‐3,6,7‐triol (II). (2001) (0)
- Total Synthesis of Crambescidins 359 and 431 (2005) (0)
- Total Syntheses of (+)-Geissoschizine, (.+-.)-Geissoschizine, and (.+-.)-(Z)-Isositsirikine. Stereocontrolled Synthesis of Exocyclic Double Bonds by Stereospecific Iminium Ion-Vinylsilane Cyclizations. (1989) (0)
- Total Synthesis of (‐)‐Crambidine (I) and Definition of the Relative Configuration of Its Unique Tetracyclic Guanidinium Core. (2006) (0)
- Cyclopalladated Ferrocenyl Amines as Enantioselective Catalysts for the Rearrangement of Allylic Imidates to Allylic Amides. (1998) (0)
- (E)‐1‐Benzyl‐3‐(1‐Iodoethylidene)Piperidine: Nucleophile‐Promoted Alkyne‐Iminium Ion Cyclizations (2003) (0)
- Catalytic Asymmetric Synthesis of all-Carbon Quaternary Stereocenters (2004) (0)
- Prins‐Pinacol Spiroannulations. (1997) (0)
- Synthesis of a Phenolic Analogue of Aphidicolin. Diminished Stereoselection in Intramolecular 6-Exo Heck Reactions of Substrates Having a Hydrocarbon Tether. (1998) (0)
- SYNTHESIS APPLICATIONS OF AZA-COPE REARRANGEMENTS. A STEREOSELECTIVE SYNTHESIS OF 9A-ARYLHYDROLILOLIDINES AND A NEW APPROACH TO THE SYNTHESIS OF ASPIDOSPERMA ALKALOIDS (1982) (0)
- Preparation of Eight-Membered Cyclic Ethers by Lewis Acid Promoted Acetal-Alkene Cyclizations. (1990) (0)
- Synthesis of Batzelladine F (2006) (0)
- Simple Method for Controlling Stereoselection in Mannich Cyclization Reactions of Aldehydes. (2010) (0)
- CATALYZED SIGMATROPIC REARRANGEMENTS. 7. PALLADIUM DICHLORIDE-PROMOTED CYCLIZATIONS OF 1,5-DIENES. A NEW METHOD FOR FORMING CYCLOHEXENES (1983) (0)
- The Synthesis of Indolizidines by Intramolecular Ene Cyclizations. (1986) (0)
- Iodide-Promoted Aldiminium Ion-Alkyne Cyclizations. A Convenient Synthesis of Substituted Tetrahydropyridines and 3- Alkylidenepiperidines. (1993) (0)
- Ring‐Enlarging Cyclopentene Annulations. (1992) (0)
- CARBONYL PARTICIPATION IN THE REACTION OF N-ACYL-2-ISOPROPENYLPYRROLIDINES WITH HALOGEN ELECTROPHILES. STEREOCONTROLLED PREPARATION OF ENANTIOMERICALLY PURE SYNTHONS FOR THE SYNTHESIS OF PUMILIOTOXIN A ALKALOIDS (1983) (0)
- Aza‐Cope Rearrangement—Mannich Cyclizations for the Formation of Complex Tricyclic Amines: Stereocontrolled Total Synthesis of (.+‐.)‐Gelsemine. (2006) (0)
- A Practical Entry to the Crambescidin Family of Guanidine Alkaloids. Enantioselective Total Syntheses of Ptilomycalin A, Crambescidin 657 and Its Methyl Ester (Neofolitispates 2), and Crambescidin 800. (2000) (0)
- Enantioselective Total Syntheses of the Cyclotryptamine Alkaloids Hodgkinsine (I) and Hodgkinsine B (II). (2003) (0)
- Ring-Enlarging Furan Annulations. (1988) (0)
- 3‐(S)‐[(tert‐Butyldiphenylsilyl)Oxy]‐2‐Butanone (2003) (0)
- A Convenient Method for the Preparation of 3‐Substituted Glutarate Diesters. (1994) (0)
- Total Synthesis of (.+-.)-Gelsemine. (2000) (0)
- Synthesis of (+)-Minfiensine (2008) (0)
- Enantioselective Synthesis of Angularly Substituted 1‐Azabicyclic Rings: Coupled Dynamic Kinetic Epimerization and Chirality Transfer. (2014) (0)
- Dynamic Kinetic Resolution via Aza-Cope Rearrangement (2010) (0)
- Synthesis of Allopumiliotoxin A Alkaloids (VI) via Iminium Ion-Vinylsilane Cyclizations. (1989) (0)
- Stereoselection in the Prins‐Pinacol Synthesis of 2,2‐Disubstituted 4‐Acyltetrahydrofurans. Enantioselective Synthesis of (‐)‐Citreoviral (XII). (2000) (0)
- Face Selectivity in Diels-Alder Reactions of Chiral Dienes Containing Allylic Substituents. (1988) (0)
- Comprar Organic Reactions, Volume 69 | Larry E. Overman | 9780470223970 | Wiley (2007) (0)
- A Naturally Occurring Erythro Diastereomer (Ic) of Pumiliotoxin B (Ia). (1989) (0)
- New Cationic Olefin Cyclization—Pinacol Reactions. Ring‐Expanding Cyclopentane Annulations that Directly Install Useful Functionality in the Cyclopentane Ring. (2003) (0)
- Synthesis Applications of Cationic Aza-Cope Rearrangements. Part 18. Scope and Mechanism of Tandem Cationic Aza-Cope Rearrangement-Mannich Cyclization Reactions. (1988) (0)
- Allylic Transposition of Alcohol and Amine Functionality by Thermal or Palladium(II)-Catalyzed Rearrangements of Allylic N- Benzoylbenzimidates. (1997) (0)
- Preparation of Seven‐Membered Ring Cyclic Ethers and 3‐Alkylidenetetrahydropyrans from the Cyclization of Oxonium Cations Derived from Unsubstituted and Silicon‐Containing 4‐Alken‐1‐ols. (1990) (0)
- Strategic Use of Pinacol‐Terminated Prins Cyclizations in Target‐Oriented Total Synthesis (2004) (0)
- Preparation of Opium Alkaloids by Palladium‐Catalyzed Bis‐Cyclizations. Formal Total Synthesis of Morphine. (1994) (0)
- The Tethered Biginelli Condensation in Natural Product Synthesis (2004) (0)
- Iminium Ion and Acyliminium Ion Initiated Cyclization Reactions of Vinylsilanes. Regiocontrolled Synthesis of Tetrahydropyridines and Related Heterocycles. (1988) (0)
- Medium Effects and the Nature of the Rate-Determining Step in Mannich-Type Cyclizations. (1988) (0)
- Preparation of Functionalized Hydroindol-3-ols via Tandem Aza-Cope Rearrangement-Mannich Cyclizations. Formal Total Synthesis of (.+-.)-6a-Epipretazettine and Related Alkaloids. (1989) (0)
- Works Title Palladium ( II )-Catalyzed Enantioselective Reactions Using COP Catalysts Permalink (2016) (0)
- First Total Synthesis of Scopadulcic Acid B. (1993) (0)
- Aprotic Chloride- and Bromide-Promoted Alkyne-Iminium Ion Cyclizations. (1996) (0)
- Nucleophile-Promoted Electrophilic Cyclization Reactions of Alkynes. (1988) (0)
- Use of Aza-Cope Rearrangement-Mannich Cyclization Reactions to Achieve a General Entry to Melodinus and Aspidosperma Alkaloids. Stereocontrolled Total Syntheses of (.+-.)-Deoxoapodine, (.+-.)- Meloscine, and (.+-.)-Epimeloscine and a Formal Synthesis of (.+-.)-1- Acetylaspidoalbidine. (1991) (0)
- Acid-Promoted Reaction of Cyclic Allylic Diols with Carbonyl Compounds. Stereoselective Ring-Enlarging Tetrahydrofuran Annulations. (1991) (0)
- Synthesis of (-)-Sarain A (2006) (0)
- Synthesis of 3‐Acyl‐3‐alkyloxindoles. (1992) (0)
- Palladium-Catalyzed Polyene Cyclizations (2010) (0)
- Total Synthesis of (‐)‐Laurenyne. Use of Acetal‐Initiated Cyclizations to Prepare Functionalized Eight‐Membered Cyclic Ethers. (1988) (0)
- Applications of Cationic Aza-Cope Rearrangements. Part 26. Enantioselective Total Synthesis of (-)-Strychnine. (1994) (0)
- Correction to "constructing quaternary stereogenic centers using tertiary organocuprates and tertiary radicals. total synthesis of trans-clerodane natural products". (2015) (0)
- P-473 STUDIES TOWARD THE TOTAL SYNTHESIS OF PALAU'AMINE (2006) (0)
- SYNTHESIS APPLICATIONS OF AZA-COPE REARRANGEMENTS. PART 8. STEREOCONTROLLED SYNTHESIS OF CYCLOHEPTA(B)PYRROLIDINES (1982) (0)
- Ligand-Controlled Diastereoselective 1,3-Dipolar Cycloadditions of Ylides with (2015) (0)
- Stereochemistry of the Prins-Pinacol Rearrangement (2010) (0)
This paper list is powered by the following services:
Other Resources About Larry E. Overman
What Schools Are Affiliated With Larry E. Overman?
Larry E. Overman is affiliated with the following schools:
