Lars Bertram
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(Suggest an Edit or Addition)Lars Bertram's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database (2007) (1775)
- Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective (2005) (1770)
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease (2014) (1591)
- A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
- Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria (2016) (1163)
- Genome-wide association study identifies 74 loci associated with educational attainment (2016) (1114)
- Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database (2008) (1064)
- The Genetics of Alzheimer Disease: Back to the Future (2010) (805)
- Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD (2005) (765)
- Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses (2008) (739)
- Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses (2016) (563)
- The genetic epidemiology of neurodegenerative disease. (2005) (561)
- Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database (2012) (546)
- Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. (2000) (521)
- New Frontiers in Alzheimer's Disease Genetics (2001) (463)
- Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. (2008) (455)
- Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (421)
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (417)
- Results of a high-resolution genome screen of 437 Alzheimer's disease families. (2003) (362)
- Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans (2010) (360)
- Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) (2015) (328)
- PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study (2017) (283)
- Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism (2015) (276)
- Genome-wide analysis identifies 12 loci influencing human reproductive behavior (2016) (250)
- New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
- Dysfunctional nitric oxide signalling increases risk of myocardial infarction (2013) (234)
- Family-based association between Alzheimer's disease and variants in UBQLN1. (2005) (233)
- Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. (2004) (225)
- Genome-wide association studies in Alzheimer's disease. (2009) (221)
- Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis (2010) (219)
- Alzheimer's disease: one disorder, too many genes? (2004) (209)
- The future of Alzheimer's disease: The next 10 years (2011) (203)
- Cohort profile: The Berlin Aging Study II (BASE-II). (2014) (201)
- Genotype‐Phenotype Relations for the Parkinson's Disease Genes Parkin, PINK1, DJ1: MDSGene Systematic Review (2018) (170)
- Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study (2013) (155)
- Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers (2013) (153)
- The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease (2015) (151)
- Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases (2009) (144)
- Directional dominance on stature and cognition in diverse human populations (2015) (144)
- The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. (2009) (142)
- The current status of Alzheimer's disease genetics: what do we tell the patients? (2004) (138)
- Nomenclature of genetic movement disorders: Recommendations of the international Parkinson and movement disorder society task force (2016) (135)
- Large-scale replication and heterogeneity in Parkinson disease genetic loci (2012) (133)
- The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects. (2010) (132)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (127)
- Nomenclature of genetic movement disorders: Recommendations of the International Parkinson and Movement Disorder Society task force (2017) (122)
- Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity (2017) (117)
- Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. (2011) (111)
- Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020. (2014) (108)
- A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants (2012) (105)
- NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases (2015) (104)
- Inflammatory biomarkers in Alzheimer's disease plasma (2019) (104)
- Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation (2016) (104)
- The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels. (2011) (97)
- Association of GSK3B with Alzheimer disease and frontotemporal dementia. (2008) (96)
- Keeping up with genetic discoveries in amyotrophic lateral sclerosis: The ALSoD and ALSGene databases (2011) (91)
- Ubiquilin 1 Modulates Amyloid Precursor Protein Trafficking and Aβ Secretion* (2006) (89)
- Decreased Catalytic Activity of the Insulin-degrading Enzyme in Chromosome 10-Linked Alzheimer Disease Families* (2007) (86)
- Family-based Association Analyses of Imputed Genotypes Reveal Genome-Wide Significant Association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3 (2015) (84)
- Rare autosomal copy number variations in early-onset familial Alzheimer’s disease (2014) (82)
- Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals (2022) (80)
- Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin. (2003) (79)
- Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum (2019) (74)
- Role of common and rare APP DNA sequence variants in Alzheimer disease (2012) (73)
- Alzheimer's Disease‐Associated Ubiquilin‐1 Regulates Presenilin‐1 Accumulation and Aggresome Formation (2011) (72)
- Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid (2019) (72)
- Assessment of Alzheimer’s disease case–control associations using family-based methods (2009) (71)
- Evidence of Altered Posteromedial Cortical fMRI Activity in Subjects at Risk for Alzheimer Disease (2010) (70)
- A QTL genome scan of the metabolic syndrome and its component traits (2003) (68)
- The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics (2018) (66)
- Dancing in the dark? (2001) (66)
- Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. (2010) (66)
- Aging magnifies the effects of dopamine transporter and D2 receptor genes on backward serial memory (2013) (65)
- Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining (2012) (65)
- New insights into the genetics of X-linked dystonia-parkinsonism (XDP, DYT3) (2015) (65)
- Paternal age is a risk factor for Alzheimer disease in the absence of a major gene (1998) (64)
- Alzheimer's disease genetics current status and future perspectives. (2009) (63)
- Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies (2000) (62)
- MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. (2013) (61)
- Towards unveiling the genetics of neurodegenerative diseases. (2011) (59)
- A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort (2019) (57)
- Editorial (2016) (57)
- PLD3 gene variants and Alzheimer's disease (2015) (57)
- The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. (2010) (55)
- No Association between CALHM1 and Alzheimer's Disease Risk (2008) (55)
- Alzheimer disease risk genes: 29 and counting (2019) (54)
- Quantifying Selective Reporting and the Proteus Phenomenon for Multiple Datasets with Similar Bias (2011) (53)
- Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer’s Disease biomarker discovery cohort (2019) (53)
- Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. (2007) (53)
- TREM 2 and Neurodegenerative Disease (2013) (53)
- Meta‐analyses identify differentially expressed microRNAs in Parkinson's disease (2019) (51)
- GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. (2009) (49)
- MicroRNA-138 is a potential regulator of memory performance in humans (2014) (48)
- MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study (2018) (48)
- Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics (2019) (48)
- Gene-environment interactions linking air pollution and inflammation in Parkinson's disease. (2016) (47)
- Insulin-degrading enzyme is genetically associated with Alzheimer’s disease in the Finnish population (2007) (45)
- PCSK 9 genetic variants and risk of type 2 diabetes : a mendelian randomisation study (2020) (45)
- Launching the movement disorders society genetic mutation database (MDSGene) (2016) (45)
- Healthy minds 0–100 years: Optimising the use of European brain imaging cohorts (“Lifebrain”) (2018) (44)
- Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease. (2008) (43)
- Impact of Parkinson's disease risk loci on age at onset (2015) (43)
- Alzheimer disease: New light on an old CLU (2010) (42)
- Chapter 9 Alzheimer's Disease Genetics (2009) (41)
- Emerging role of Alzheimer's disease-associated ubiquilin-1 in protein aggregation. (2010) (41)
- Alzheimer’s Genetics in the GWAS Era: A Continuing Story of ‘Replications and Refutations’ (2011) (40)
- Genetic research in schizophrenia: new tools and future perspectives. (2008) (40)
- Dopaminergic Gene Polymorphisms Affect Long-term Forgetting in Old Age: Further Support for the Magnification Hypothesis (2013) (40)
- Distinguishing true from false positives in genomic studies: p values (2013) (39)
- Aging and KIBRA/WWC1 genotype affect spatial memory processes in a virtual navigation task (2013) (39)
- COMT polymorphism and memory dedifferentiation in old age. (2014) (39)
- The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk (2014) (38)
- Lower baseline performance but greater plasticity of working memory for carriers of the val allele of the COMT Val¹⁵⁸Met polymorphism. (2015) (38)
- Individual variations in ‘brain age’ relate to early-life factors more than to longitudinal brain change (2021) (37)
- Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database. (2015) (37)
- Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk (2013) (36)
- Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium (2009) (36)
- Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women (2020) (35)
- Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay (2019) (35)
- Genome-wide significant association with seven novel multiple sclerosis risk loci (2015) (35)
- Alzheimer's disease: The latest suspect (2008) (35)
- Correction: Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study (2013) (34)
- Of replications and refutations: The status of Alzheimer’s disease genetic research (2001) (33)
- The Val/Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene predicts decline in perceptual speed in older adults. (2014) (33)
- Cysteine 27 Variant of the δ-Opioid Receptor Affects Amyloid Precursor Protein Processing through Altered Endocytic Trafficking (2011) (33)
- No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease (2001) (32)
- Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects (2012) (31)
- Gene-Environment Interaction in Parkinson's Disease: Coffee, ADORA2A, and CYP1A2 (2016) (31)
- Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease. (2016) (29)
- Educational attainment does not influence brain aging (2021) (29)
- Disentangling the genetics of lean mass. (2019) (28)
- Effects of Ubiquilin 1 on the Unfolded Protein Response (2009) (28)
- Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset (2019) (28)
- Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score. (2016) (27)
- Dopamine and glutamate receptor genes interactively influence episodic memory in old age (2014) (27)
- Relationship between genetic risk factors and markers for Alzheimer's disease pathology. (2012) (27)
- Family-Based Association between Alzheimer ’ s Disease and Variants in UBQLN 1 (2005) (26)
- Independent replication of STAT3 association with multiple sclerosis risk in a large German case–control sample (2012) (26)
- Lack of Replication of the GRIN2A-by-Coffee Interaction in Parkinson Disease (2014) (26)
- The role of genetics for biomarker development in neurodegeneration (2011) (26)
- Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9 (2018) (25)
- Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data (2020) (25)
- Meta-analyses identify differentially expressed microRNAs in Parkinson’s disease (2018) (24)
- Genomic mechanisms in Alzheimer's disease (2020) (24)
- Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development (2021) (23)
- Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (22)
- Effects of aging and dopamine genotypes on the emergence of explicit memory during sequence learning (2013) (22)
- Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease. (2013) (22)
- Exploring candidate gene associations with neuropsychological performance (2007) (21)
- Genome-wide study identifies 611 loci associated with risk tolerance and risky behaviors (2018) (21)
- Dopamine modulates attentional control of auditory perception: DARPP-32 (PPP1R1B) genotype effects on behavior and cortical evoked potentials (2013) (20)
- Association of UBQLN1 mutation with Brown–Vialetto–Van Laere syndrome but not typical ALS (2012) (20)
- Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan (2020) (19)
- APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease (2020) (19)
- The LDLR locus in alzheimer's disease: A family-based study and meta-analysis of case-control data (2007) (18)
- PEN2 is not a genetic risk factor for Alzheimer’s disease in a large family sample (2004) (18)
- Family‐based association test for time‐to‐onset data with time‐dependent differences between the hazard functions (2006) (18)
- Is α-T catenin (VR22) an Alzheimer’s disease risk gene? (2006) (17)
- Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients (2000) (16)
- Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin (2017) (16)
- Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development (2020) (15)
- Cohort profile: follow-up of a Berlin Aging Study II (BASE-II) subsample as part of the GendAge study (2021) (15)
- Assessment of microRNA-related SNP effects in the 3′ untranslated region of the IL22RA2 risk locus in multiple sclerosis (2014) (15)
- TREM2 and neurodegenerative disease. (2013) (14)
- Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach (2021) (14)
- Association of GSK 3 B With Alzheimer Disease and Frontotemporal Dementia (2008) (14)
- Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer’s Disease Multimodal Biomarker Discovery Cohort (2020) (14)
- Further evidence for LBP-1c/CP2/LSF association in Alzheimer’s disease families (2005) (14)
- Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using integrative bioinformatics. (2018) (14)
- CALHM1 P86L polymorphism does not alter amyloid-β or tau in cerebrospinal fluid (2010) (14)
- No association between a previously reported OLR1 3′ UTR polymorphism and Alzheimer’s disease in a large family sample (2004) (13)
- Is alpha-T catenin (VR22) an Alzheimer's disease risk gene? (2007) (13)
- Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples. (2006) (13)
- Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360) (2017) (12)
- Healthy minds 0–100 years: Optimising the use of European brain imaging cohorts (“Lifebrain”) (2018) (12)
- Follow‐up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort (2007) (12)
- Genetic risk for Alzheimer’s disease predicts hippocampal volume through the lifespan (2019) (11)
- Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients (2016) (11)
- Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation (2011) (11)
- Next Generation Sequencing in Alzheimer's Disease. (2016) (11)
- Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (11)
- A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools (2014) (11)
- Clinico-genetic findings in 509 frontotemporal dementia patients (2021) (11)
- Self-reported Sleep Problems Related to Amyloid Deposition in Cortical Regions with High HOMER1 Gene Expression. (2019) (11)
- Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE-ε4/TOMM40 long poly-T repeat allele variants (2019) (11)
- Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families (2015) (10)
- Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers (2022) (10)
- New insights into the genetics of X-linked dystonia-parkinsonism ( XDP , DYT 3 ) (2015) (10)
- Mutation spectrum and polygenic score in German patients with familial hypercholesterolemia (2020) (10)
- TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels (2021) (9)
- Ubiquilin-1 modulates γ-secretase-mediated ε-site cleavage in neuronal cells. (2013) (9)
- Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS (2015) (9)
- Vitamin D supplementation is associated with slower epigenetic aging (2021) (9)
- Replication study of plasma proteins relating to Alzheimer's pathology (2021) (8)
- Relationship between Lipoprotein (a) and cognitive function – Results from the Berlin Aging Study II (2020) (8)
- Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation (2010) (8)
- Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II) (2016) (8)
- Obesity and the brain: a possible genetic link (2010) (8)
- Plasma Proteomic Biomarkers Relating to Alzheimer’s Disease: A Meta-Analysis Based on Our Own Studies (2021) (8)
- Relationship between five Epigenetic Clocks, Telomere Length and Functional Capacity assessed in Older Adults: Cross-sectional and Longitudinal Analyses (2021) (8)
- Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (8)
- Genome sequencing identifies a novel mutation in ATP1A3 in a family with dystonia in females only (2014) (8)
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (7)
- Field synopsis and systematic meta-analyses of genetic association studies in isolated dystonia. (2018) (7)
- Relationship between five Epigenetic Clocks, Telomere Length and Functional Capacity assessed in Older Adults: Cross-sectional and Longitudinal Analyses. (2022) (7)
- Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort (2021) (7)
- Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity (2017) (7)
- Seven-CpG DNA Methylation Age Determined by Single Nucleotide Primer Extension and Illumina’s Infinium MethylationEPIC Array Provide Highly Comparable Results (2021) (7)
- Aging and a genetic KIBRA polymorphism interactively affect feedback- and observation-based probabilistic classification learning (2018) (7)
- Genetic risk scores and hallucinations in patients with Parkinson disease (2020) (6)
- Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2 (2021) (6)
- Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer’s disease CSF profile of neuronal injury and inflammation (2022) (6)
- Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer’s disease CSF profile of neuronal injury and inflammation (2022) (6)
- Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019) (6)
- Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests (2009) (6)
- On the Meta-Analysis of Genome-Wide Association Studies: A Robust and Efficient Approach to Combine Population and Family-Based Studies (2012) (6)
- Differential microRNA expression analyses across two brain regions in Alzheimer’s disease (2022) (6)
- Developing the “next generation” of genetic association databases for complex diseases (2012) (5)
- ACAT1 is not associated with Alzheimer's disease in two independent family-based samples (2005) (5)
- Most Pathways Can Be Related to the Pathogenesis of Alzheimer’s Disease (2022) (5)
- TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer’s disease biomarker levels (2020) (5)
- Genetic variants in PSEN2 and correlation to CSF β-amyloid42 levels in AD (2012) (5)
- Call for participation in the neurogenetics consortium within the Human Variome Project (2011) (4)
- Associations of circulating C-reactive proteins, APOE ε4, and brain markers for Alzheimer’s disease in healthy samples across the lifespan (2021) (4)
- A metabolite-based machine learning approach to diagnose Alzheimer’s-type dementia in blood: Results from the European Medical Information Framework for Alzheimer’s Disease biomarker discovery cohort (2019) (4)
- Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset (2022) (4)
- No association between CTNNBL1 and episodic memory performance (2014) (4)
- Self-reported sleep relates to microstructural hippocampal decline in ß-amyloid positive Adults beyond genetic risk (2021) (3)
- The hSNM1B/Apollo variant rs11552449 is associated with cellular sensitivity towards mitomycin C and ionizing radiation. (2018) (3)
- Probing the exome in Alzheimer disease and other neurodegenerative disorders. (2015) (3)
- Cohort Profile Update: GendAge and Berlin Aging Study II (BASE-II) (2020) (3)
- “Brain age” relates to early life factors but not to accelerated brain aging (2021) (3)
- Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer’s Disease Pathology (2020) (3)
- MICRORNA EXPRESSION IN ALZHEIMER DISEASE: A SYSTEMATIC REVIEW OF THE LITERATURE AND META-ANALYSIS (2017) (3)
- Neurodegenerative Diseases: Genetics of Alzheimer's disease (2005) (3)
- Probing the epigenome by EWAS: A new era in brain disease research (2015) (3)
- Databases for neurogenetics: Introduction, overview, and challenges (2012) (3)
- BDNF serum concentrations in 2053 participants of the Berlin Aging Study II (2021) (3)
- Large-scale genetic study of risk tolerance and risky behaviors identifies new loci and reveals shared genetic influences (2017) (3)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (3)
- Epigenetic aging and perceived psychological stress in old age (2022) (3)
- CSF Proteomic Alzheimer’s Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals (2021) (3)
- Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated in two separate birth cohorts (2022) (3)
- Family‐Based Tests of Association in the Presence and Absence of Known Linkage (2001) (3)
- Genome-wide analysis furthers decoding of Alzheimer disease genetics (2022) (3)
- Correspondence to Sand et al. “Critical Reappraisal of a Catechol-O-Methyltransferase Transversion Variant in Schizophrenia” (2010) (2)
- Self-Reported Sleep Relates to Microstructural Hippocampal Decline in β-Amyloid Positive Adults Beyond Genetic Risk (2020) (2)
- Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates (2022) (2)
- Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease (2021) (2)
- Taking genomics research to the next level: The Genotype‐Tissue expression project (2018) (2)
- Genetics of Neurodegenerative Diseases (2012) (2)
- No association between marker D10S1423 and Alzheimer's disease (2003) (2)
- Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition (2022) (2)
- A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples (2021) (2)
- New light on an old CLU (2010) (2)
- A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging (2021) (2)
- Multiomics profiling of human plasma and CSF reveals ATN derived networks and highlights causal links in Alzheimer's disease (2022) (1)
- Candidate genes showing no evidence of association with Alzheimer disease — Results of the Nimh-Alzheimer disease genetics initiative (2000) (1)
- S2-01-01 Systematic meta-analysis of Alzheimer’s disease genetic association studies - the AlzGene database (2006) (1)
- MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study (2018) (1)
- Bioinformatics meets biology: Predicting the role of DNA-sequence variants on micro-RNA function (2013) (1)
- Reply letter to Jinnah “Locus pocus” and Albanese “Complex dystonia is not a category in the new 2013 consensus classification”: Necessary evolution, no magic! (2016) (1)
- GENOMICS AND EPIGENOMICS ANALYSES IN THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY (2018) (1)
- Candidate Genes Showing No Evidence of Association with Alzheimer's Disease: Results of the NIMH‐AD Genetics Initiative (2002) (1)
- 14 Alzheimer’s Disease: Genetics, Pathogenesis, Models, and Experimental Therapeutics (2008) (1)
- DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN AND ALZHEIMER’S DISEASE PROGRESSION (2018) (1)
- Predicting AT(N) pathologies in Alzheimer’s disease from blood-based proteomic data using neural networks (2022) (1)
- Rare variants in IFFO1, DTNB and NLRC3 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation (2021) (1)
- Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data (2020) (1)
- Alzheimer's disease risk SNPs show no strong effect on miRNA expression in human lymphoblastoid cell lines (2020) (1)
- Genetic Risk Factors: Their Function and Comorbidities in Alzheimer's Disease (2011) (1)
- Genetic associations with learning over 100 days of practice (2022) (1)
- Erratum to “Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Approach” (2022) (1)
- Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non‐Alzheimer's disease pathophysiology (2022) (1)
- Field synopsis and systematic meta-analyses of genetic association studies in isolated dystonia (2018) (1)
- Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults (2021) (1)
- EUROPEAN MEDICAL INFORMATION FRAMEWORK FOR ALZHEIMER’S DISEASE (EMIF-AD): THE BIOMARKER DISCOVERY STUDY (2017) (1)
- Assessment of Alzheimer's disease risk genes with CSF-biomarker levels (2013) (1)
- Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using genome-wide analyses (2018) (1)
- Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men. (2022) (1)
- DNA Methylation Age Acceleration, Type 2 Diabetes, and its Complications: Cross-Sectional and Longitudinal Data from the Berlin Aging Study II (BASE-II) (2022) (1)
- INCF Workshop on Genetic Disease Models of Psychiatric and Neurological Diseases (2018) (0)
- A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, fluid biomarkers, cognition and clinical status (2013) (0)
- Sex-specific metabolic pathways associate with Alzheimer's Disease (AD) endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery (EMIF-AD MBD) cohort (2021) (0)
- P1-354 Cross sectional and longitudinal analysis of Alzheimer’s disease quantitative phenotypes (2006) (0)
- Chapter 85 – Alzheimer’s Disease (2013) (0)
- Alzheimer’s disease risk SNPs show no strong effect on miRNA expression in human lymphoblastoid cell lines (2018) (0)
- Common signatures of differential microRNA expression in Parkinson’s and Alzheimer’s disease brains (2022) (0)
- A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets (2022) (0)
- DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER\textquotesingleS DISEASE PATHOLOGY AND PROGRESSION (2017) (0)
- PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER’S DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT (2018) (0)
- Sleep duration and brain structure – phenotypic associations and genotypic covariance (2022) (0)
- Genetic associations with learning over 100 days of practice (2022) (0)
- RETRACTED: Genome-wide assessment of copy number variations in early-onset Alzheimer's disease (2011) (0)
- Examining the shared genetic architecture of risk tolerance and related behaviors (2017) (0)
- Edinburgh Research Explorer Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2018) (0)
- Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer’s disease (2023) (0)
- Biology meets bioinformatics: Validating the predicted role of Alzheimer's GWAS SNPs on micro-RNA function (2013) (0)
- Multiomics machine learning identifies sleep and inflammation molecular pathways in prodromal Alzheimer's Disease (2023) (0)
- Title Gene-Environment Interaction in Parkinson ' s Disease : Coffee , ADORA 2 A , and CYP 1 A 2 Permalink (2017) (0)
- Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- GMNC risk alleles in individuals with Alzheimer’s disease are associated with cerebrospinal fluid concentrations of proteins involved in neuronal plasticity and blood brain barrier function (2022) (0)
- Contents Vol. 47, 2016 (2017) (0)
- Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers (2013) (0)
- Meta-Analysis Evaluation of the Potential Excess of Statistically Significant Findings in Published Genetic Association Studies : Application to Alzheimer ’ s Disease (2008) (0)
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (0)
- Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease. (2023) (0)
- Genes for Well-Being, Depression, and Neuroticism: No Need to Worry—We Are Largely Responsible for our own Happiness (2016) (0)
- Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- Significant association of coding (Missense) SNPs with familial LOAD based on a functional genome-wide association screen (2011) (0)
- large family sample 3 ' UTR polymorphism and Alzheimer ’ s disease in a OLR 1 No association between a previously reported (2004) (0)
- FC9 Comprehensive review and field synopsis of genetic associations in cutaneous melanoma (2010) (0)
- RELATIONSHIP BETWEEN METABOLIC HEALTH AND 5 EPIGENETIC CLOCKS IN THE BERLIN AGING STUDY II (BASE-II) (2022) (0)
- P1-281 Genetic association analysis of BACE2 with Alzheimer’s disease (2006) (0)
- Exome‐wide rare variant analysis of Alzheimer’s disease biomarkers: The EMIF‐AD multimodal biomarker discovery study (2021) (0)
- The genetic basis of episodic memory performance in the elderly: Is there a link to micro-RNAs? (2013) (0)
- A ROUTINE BLOOD PARAMETER BIOLOGICAL AGE COMPOSITE IS ASSOCIATED WITH FRAILTY IN THE BERLIN AGING STUDY II (BASE-II) (2022) (0)
- ASSOCIATIONS BETWEEN CEREBROSPINAL FLUID NEURODEGENERATIVE MARKERS, NEUROFILAMENT-LIGHT AND TOTAL TAU AND CEREBROVASCULAR IMAGING MARKERS (2019) (0)
- ASSOCIATION OF CSF TAU WITH HYPERPLASTICITY IN ALZHEIMER’S DISEASE (2019) (0)
- Supplementary Material for%3A Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II) (2016) (0)
- TO JMG No association between a previously reported OLR 1 3 9 UTR polymorphism and Alzheimer ’ s disease in a large family sample (2004) (0)
- [P1–291]: WITHDRAWN (2017) (0)
- Assessment of microRNA-related SNP effects in the 3′ untranslated region of the IL22RA2 risk locus in multiple sclerosis (2014) (0)
- RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT-LIGHT AND YKL-40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY (2018) (0)
- MRI PREDICTORS OF AMYLOID PATHOLOGY: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY (2018) (0)
- Alzheimer disease DNA sequence variants in APP Role of common and rare (2012) (0)
- New Zealand Applied Neurosciences Conference. Auckland, New Zealand, November 24-26, 2016: Abstracts (2016) (0)
- The genetics of Alzheimer's disease. (2008) (0)
- P4-102 Functional analysis of the insulin degrading enzyme in genetically-associated AD families (2004) (0)
- P4-119 Genetic association of UBQLN1 and Alzheimer's disease in multiple independent study populations (2004) (0)
- Correction: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses (2016) (0)
- Correction: Individual variations in ‘Brain Age’ relate to early-life factors more than to longitudinal brain change (2022) (0)
- Assessment and Genetic Associations of the 2d:4d Finger-Length Ratio within the Berlin Aging Study Ii (Base-Ii) (2012) (0)
- Genome-wide association study of Alzheimer's disease brain imaging biomarkers and neuropsychological phenotypes in the EMIF-AD Multimodal Biomarker Discovery dataset (2021) (0)
- INCREASED CSF AMYLOID-β 1-38 AND 1-40 CONCENTRATIONS IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT WITH TAU BUT WITHOUT AMYLOID PATHOPHYSIOLOGY (2018) (0)
- P1-204 Effects of ubiquilin-1 RNA interference (RNA1) on APP processing (2004) (0)
- Differential expression of microRNAs in Alzheimer’s disease brain, blood and cerebrospinal fluid: a systematic review and meta-analysis (2018) (0)
- P3-262: Assessment of Alzheimer's disease case-control association findings in a large collection of family-based samples (2008) (0)
- DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT (2017) (0)
- Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease (2020) (0)
- Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals (2018) (0)
- Comprehensive Research Synopsis and Systematic Meta-Analyses in ALS Genetics: The ALSGene Database (P01.095) (2012) (0)
- Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease (2022) (0)
- Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (0)
- Alzheimer's disease genetics: Current status and future perspectives (2009) (0)
- Reply to Neupane et al.: Replication study of AD‐associated rare variants (2022) (0)
- DNA methylation differences associated with peripheral biomarkers in the EMIF‐AD cohort (2020) (0)
- Modemagazine in Japan (2009) (0)
- Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning (2022) (0)
- Allele-specific miRNA mediated regulation of APP expression (2012) (0)
- Sleep Efficiency Relates to Hippocampal Integrity Decline in β-Amyloid Positive Adults (2020) (0)
- identifies 148 independent genetic loci influencing general cognitive function Permalink (2018) (0)
- ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology (2013) (0)
- PREDICTING COGNITIVE DECLINE THROUGH STRUCTURAL MRI BIOMARKERS: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY (2018) (0)
- 6 THE GENETICS OF NEURODEGENERATIVE DISEASE (2012) (0)
- Relationship between Lipoprotein (a) and cognitive function – Results from the Berlin Aging Study II (2020) (0)
- Genome‐wide association study on Alzheimer’s disease CSF profiles in the EMIF‐AD MBD and ADNI datasets (2022) (0)
- microRNA-mediated regulation of APP expression (2010) (0)
- Thirty years of Alzheimer's genetics: what's new and what's next? (2010) (0)
- Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans (2022) (0)
- A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, fluid biomarkers, cognition and clinical status (2013) (0)
- Is it real? the short history of genome-wide association findings in Alzheimer's disease (2010) (0)
- FEELING YOUNGER, BEING YOUNGER: ASSOCIATIONS BETWEEN BIOLOGICAL AGE AND SUBJECTIVE AGE IN OLDER ADULTS (2019) (0)
- Independent replication of STAT3 association with multiple sclerosis risk in a large German case–control sample (2011) (0)
- CSF Proteome Changes Depend on APOE Genotype in Prodromal AD (2022) (0)
- Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. (2022) (0)
- Author response for "Mutation spectrum and polygenic score in German patients with familial hypercholesterolemia" (2020) (0)
- P1-274 In search of novel Alzheimer’s disease genes on chromosome 19 (2006) (0)
- DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION (2017) (0)
- EFFECT OF A COMMON UMOD VARIANT ON RENAL FUNCTION, BLOOD PRESSURE, AND FITNESS IN A COMMUNITY-BASED COHORT OF ELDERLY SUBJECTS (2021) (0)
- DNA methylation age acceleration is associated with risk of diabetes complications (2023) (0)
- Field synopsis of genetic association studies in Schizophrenia (2010) (0)
- IC-P-071 The effect of APOE-4 on fMRI deactivation in older controls, MCI subjects and AD patients (2006) (0)
- Assessment of Alzheimer’s disease polygenic risk score on longitudinal amyloid accumulation in cognitively intact older adults (2021) (0)
- PROTEIN QUANTITATIVE TRAIT LOCI (PQTL) MAPPING OF THE CEREBROSPINAL FLUID PROTEOME (2022) (0)
- VITAMIN D DEFICIENCY AND FASTER EPIGENETIC AGING: RESULTS FROM THE BERLIN AGING STUDY II (BASE-II) (2022) (0)
- O4-01-02 The effect of APOE-4 on fMRI deactivation in older controls, MCI subjects and AD patients (2006) (0)
- Identification of plasma proteome signatures associated with ATN framework using SOMAscan (2020) (0)
- P045. The MelGene database: A field synopsis of genetic association studies in cutaneous melanoma (2011) (0)
- The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics (2018) (0)
- High Air Pollution and Extrinsic Skin Aging: Results from a Population-Based Cohort (2018) (0)
- Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease implicates mediation through GPX3 (2022) (0)
- Alzheimer’s disease genetic risk variants show brain cell type‐specific associations with protein levels in cerebrospinal fluid (2021) (0)
- Cerebrospinal fluid tau levels indicate aberrant neuronal plasticity in Alzheimer disease (2020) (0)
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What Schools Are Affiliated With Lars Bertram?
Lars Bertram is affiliated with the following schools:
