Lars Eckmann
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Computer Science
Lars Eckmann's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Lars Eckmann's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. (2009) (1888)
- IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer (2004) (1782)
- A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. (1995) (1280)
- Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth (2012) (1060)
- Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface (2008) (907)
- Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing (2005) (753)
- Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry (1993) (692)
- Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. (1999) (684)
- Epithelial cells as sensors for microbial infection. (1997) (631)
- Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells (2006) (611)
- Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. (1993) (567)
- Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. (1997) (559)
- Ulcerative colitis (2012) (546)
- Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis (2007) (512)
- Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. (2005) (432)
- A NOD2–NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide (2008) (399)
- The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4 (2004) (393)
- NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ (2007) (375)
- NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria. (1999) (365)
- Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease (2019) (365)
- Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells. (1997) (364)
- NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. (2007) (312)
- Cell Differentiation Is a Key Determinant of Cathelicidin LL-37/Human Cationic Antimicrobial Protein 18 Expression by Human Colon Epithelium (2002) (305)
- Apoptosis of human intestinal epithelial cells after bacterial invasion. (1998) (300)
- Cytokines in host defense against Salmonella. (2001) (287)
- Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. (2001) (249)
- Cathelicidin Mediates Innate Intestinal Defense against Colonization with Epithelial Adherent Bacterial Pathogens1 (2005) (240)
- Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. (2003) (231)
- Mucosal defences against Giardia (2003) (228)
- Chemokine receptor expression by human intestinal epithelial cells. (1999) (228)
- Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells. (2001) (216)
- How bile acids confer gut mucosal protection against bacteria. (2006) (211)
- Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production. (1997) (207)
- Clearance of Citrobacter rodentium Requires B Cells but Not Secretory Immunoglobulin A (IgA) or IgM Antibodies (2004) (207)
- Central Importance of Immunoglobulin A in Host Defense against Giardia spp (2002) (205)
- Analysis by High Density cDNA Arrays of Altered Gene Expression in Human Intestinal Epithelial Cells in Response to Infection with the Invasive Enteric BacteriaSalmonella * (2000) (205)
- NOD2 contributes to cutaneous defense against Staphylococcus aureus through α-toxin-dependent innate immune activation (2009) (204)
- Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. (1994) (199)
- Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intercellular adhesion molecule-1 (ICAM)-1) expression and neutrophil adhesion. (1996) (188)
- NOD2 and Crohn's disease: loss or gain of function? (2005) (181)
- Nitric Oxide Production by Human Intestinal Epithelial Cells and Competition for Arginine as Potential Determinants of Host Defense Against the Lumen-Dwelling Pathogen Giardia lamblia1 (2000) (179)
- IκB-kinaseβ-dependent NF-κB activation provides radioprotection to the intestinal epithelium (2004) (176)
- IL-6-Dependent Mucosal Protection Prevents Establishment of a Microbial Niche for Attaching/Effacing Lesion-Forming Enteric Bacterial Pathogens1 (2008) (174)
- Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells. (2008) (169)
- Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. (2002) (166)
- Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells. (1998) (165)
- Intestinal Epithelial Cell Apoptosis following Cryptosporidium parvum Infection (2000) (153)
- Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines (1997) (153)
- Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation (2011) (151)
- Opposing functions of IKKβ during acute and chronic intestinal inflammation (2008) (151)
- Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2 (2003) (150)
- Nuclear factor-kappa B in intestinal protection and destruction (2009) (145)
- Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha. (1995) (145)
- The regulation and functional consequence of proinflammatory cytokine binding on human intestinal epithelial cells. (1998) (143)
- Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice (2015) (142)
- Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts. (2001) (136)
- Gut-liver axis at the frontier of host-microbial interactions. (2017) (127)
- Intestinal epithelial cells as watchdogs for the natural immune system. (1995) (119)
- A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia (2013) (116)
- Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells (2007) (115)
- Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion. (1997) (113)
- Innate immune defenses in the intestinal tract (2007) (113)
- Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella‐induced apoptosis in intestinal epithelial cells (2002) (112)
- Cyclic AMP Promotes cAMP-responsive Element-binding Protein-dependent Induction of Cellular Inhibitor of Apoptosis Protein-2 and Suppresses Apoptosis of Colon Cancer Cells through ERK1/2 and p38 MAPK* (2004) (111)
- Genetically resistant (Ityr) and susceptible (Itys) congenic mouse strains show similar cytokine responses following infection with Salmonella dublin. (1996) (111)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells (1993) (105)
- IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium. (2004) (105)
- D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways. (1997) (104)
- Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia. (2011) (103)
- Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches (2009) (98)
- A Bioadhesive Nanoparticle-Hydrogel Hybrid System for Localized Antimicrobial Drug Delivery. (2016) (96)
- Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion (1997) (94)
- Polymeric Immunoglobulin Receptor in Intestinal Immune Defense against the Lumen-Dwelling Protozoan Parasite Giardia1 (2006) (91)
- Regulated production of the chemokine CCL28 in human colon epithelium. (2004) (91)
- Human Intestinal Epithelial Cells Respond toCryptosporidium parvum Infection with Increased Prostaglandin H Synthase 2 Expression and Prostaglandin E2and F2α Production (1998) (90)
- Nuclear factor-κB activation promotes restitution of wounded intestinal epithelial monolayers (2003) (89)
- Microbiota Protects Mice Against Acute Alcohol-Induced Liver Injury. (2015) (88)
- Animal Models of Inflammatory Bowel Disease (2006) (87)
- Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells (1996) (87)
- An Important Role for Polymeric Ig Receptor-Mediated Transport of IgA in Protection against Streptococcus pneumoniae Nasopharyngeal Carriage1 (2004) (86)
- Human Milk Oligosaccharides Protect Against Enteropathogenic Escherichia coli Attachment In Vitro and EPEC Colonization in Suckling Mice (2014) (85)
- CXCR2-Dependent Mucosal Neutrophil Influx Protects against Colitis-Associated Diarrhea Caused by an Attaching/Effacing Lesion-Forming Bacterial Pathogen1 (2009) (84)
- Sensor molecules in intestinal innate immunity against bacterial infections (2005) (83)
- Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. (1994) (83)
- Ubiquitous production of macrophage migration inhibitory factor by human gastric and intestinal epithelium. (2002) (82)
- Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. (2011) (82)
- Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes (2017) (80)
- Cholera toxin and cholera toxin B subunit induce IgA switching through the action of TGF-beta 1. (1998) (79)
- The effect of stem cell proliferation regulators demonstrated with an in vitro assay. (1988) (79)
- Pathogenesis of Cryptosporidium parvum infection. (1999) (78)
- GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen. (2010) (77)
- IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia. (2015) (74)
- Innate immunity and mucosal bacterial interactions in the intestine (2004) (73)
- Production of MDC/CCL22 by human intestinal epithelial cells. (2001) (71)
- Use of Recombinant Entamoeba histolytica Cysteine Proteinase 1 To Identify a Potent Inhibitor of Amebic Invasion in a Human Colonic Model (2007) (68)
- Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production (2010) (67)
- Characterization of Candidate Live Oral Salmonella typhi Vaccine Strains Harboring Defined Mutations inaroA, aroC, and htrA (1999) (65)
- Defence molecules in intestinal innate immunity against bacterial infections (2005) (64)
- TLR3, TRIF, and Caspase 8 Determine Double-Stranded RNA-Induced Epithelial Cell Death and Survival In Vivo (2013) (63)
- Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids (2016) (63)
- The lymphotoxin-beta receptor is critical for control of murine Citrobacter rodentium-induced colitis. (2004) (63)
- Modulation of chloride secretory responses and barrier function of intestinal epithelial cells by the Salmonella effector protein SigD. (2004) (63)
- Chemokine secretion of human cells in response to Toxoplasma gondii infection. (1999) (62)
- Role of alphabeta and gammadelta T cells in the host response to Salmonella infection as demonstrated in T-cell-receptor-deficient mice of defined Ity genotypes (1997) (61)
- A Surface Amebic Cysteine Proteinase Inactivates Interleukin-18 (2003) (60)
- A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro. (2010) (60)
- Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia. (2009) (59)
- Impaired Parasite Attachment as Fitness Cost of Metronidazole Resistance in Giardia lamblia (2011) (58)
- A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target* (2010) (58)
- Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. (2014) (57)
- Should We Divide Crohn's Disease Into Ileum-Dominant and Isolated Colonic Diseases? (2019) (57)
- Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia (2015) (56)
- Nod2 Mediates Susceptibility to Yersinia pseudotuberculosis in Mice (2008) (55)
- Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells. (2005) (55)
- Adaptive Immunity-Dependent Intestinal Hypermotility Contributes to Host Defense against Giardia spp (2006) (54)
- Intestinal mucosal responses to microbial infection (2005) (54)
- Role of αβ and γδ T Cells in the Host Response toSalmonella Infection as Demonstrated in T-Cell-Receptor-Deficient Mice of Defined Ity Genotypes (1998) (54)
- New approaches to the treatment of giardiasis (2011) (52)
- Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity (2013) (52)
- Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets. (2012) (51)
- Α1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model. (2011) (50)
- Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis. (2015) (49)
- Prolonged interferon-gamma exposure decreases ion transport, NKCC1, and Na+-K+-ATPase expression in human intestinal xenografts in vivo. (2004) (49)
- Microbes and microbial toxins: paradigms for microbial-mucosal interactions I. Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogen Giardia lamblia. (2001) (49)
- Synergistic interactions allow colony formation in vitro by murine haemopoietic stem cells. (1990) (48)
- Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia (2016) (47)
- Treatment of Giardiasis: Current Status and Future Directions (2014) (45)
- Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis (2016) (45)
- Epithelial Cell IκB-Kinase β Has an Important Protective Role in Clostridium difficile Toxin A-Induced Mucosal Injury1 (2006) (44)
- Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer (2015) (43)
- STAT3 and its activators in intestinal defense and mucosal homeostasis (2010) (42)
- Intestinal Epithelial Cells (1996) (42)
- Phosphorylation of eIF2&agr; Is Dispensable for Differentiation but Required at a Posttranscriptional Level for Paneth Cell Function and Intestinal Homeostasis in Mice (2014) (41)
- Importance of interleukin-10 in genetic susceptibility of mice to Coccidioides immitis. (1998) (41)
- Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites (2015) (41)
- Expression of Epstein–Barr virus‐induced gene 3 and other interleukin‐12‐related molecules by human intestinal epithelium (2004) (40)
- Protection against colitis by CD100 dependent modulation of intraepithelial γδ T lymphocyte function (2013) (39)
- Analysis of host responses to microbial infection using gene expression profiling. (2001) (39)
- Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production (2022) (37)
- Hsp90 Inhibitors as New Leads To Target Parasitic Diarrheal Diseases (2014) (37)
- Tumor promotion by caspase-resistant retinoblastoma protein (2005) (36)
- Trp53 Deficiency Protects against Acute Intestinal Inflammation (2013) (36)
- Entamoeba histolytica Induces Intestinal Cathelicidins but Is Resistant to Cathelicidin-Mediated Killing (2011) (35)
- IL-8 secreted by epithelial cells invaded by bacteria. (1993) (35)
- Salmonella Infection Induces a Hypersecretory Phenotype in Human Intestinal Xenografts by Inducing Cyclooxygenase 2 (2003) (33)
- The fecal mycobiome in non-alcoholic fatty liver disease (2021) (32)
- Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury. (2006) (31)
- Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. (2001) (30)
- Interleukin (IL)-21 in Inflammation and Immunity During Parasitic Diseases (2019) (30)
- Complex Network of NKT Cell Subsets Controls Immune Homeostasis in Liver and Gut (2018) (30)
- Rapid detachment of Giardia lamblia trophozoites as a mechanism of antimicrobial action of the isoflavone formononetin. (2010) (29)
- Nuclear factor-kappa B activation promotes restitution of wounded intestinal epithelial monolayers. (2003) (28)
- CYP2E1 expression in human lymphocytes from various ethnic populations. (1999) (28)
- Attenuation of Intestinal Inflammation in Interleukin-10-Deficient Mice Infected with Citrobacter rodentium (2014) (28)
- Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo. (2016) (28)
- ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection (2017) (27)
- Murine models of vaginal trichomonad infections. (2011) (26)
- Human intestinal epithelial cells express receptors for platelet-activating factor. (1999) (23)
- Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts (2018) (22)
- Adaptive immune response in symptomatic and asymptomatic enteric protozoal infection: evidence for a determining role of parasite genetic heterogeneity in host immunity to human giardiasis. (2016) (22)
- Nuclear Expression of β-Catenin Promotes RB Stability and Resistance to TNF-Induced Apoptosis in Colon Cancer Cells (2013) (21)
- Importance of Interleukin-10 in Genetic Susceptibility of Mice to Coccidioides immitis (1998) (20)
- Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity (2008) (20)
- Innate immune defence: NOD2 and autophagy in the pathogenesis of Crohn's disease. (2010) (20)
- Cytokine-induced differentiation of IgA B cells: studies using an IgA expressing B-cell lymphoma. (1992) (20)
- Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes (2021) (19)
- Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera (2018) (19)
- β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells (2019) (19)
- Engulfment and Cell Motility Protein 1 (ELMO1) Has an Essential Role in the Internalization of Salmonella Typhimurium Into Enteric Macrophages That Impact Disease Outcome (2015) (19)
- Voltammetry of nitrobenzene with cysteine and other acids in DMSO. Implications for the biological reactivity of reduced nitroaromatics with thiols (2013) (18)
- Sphingosine 1-phosphate modulation and immune cell trafficking in inflammatory bowel disease (2022) (17)
- Increased transcription and coordinate stabilization of mRNAs for secreted immunoglobulin alpha heavy chain and kappa light chain following stimulation of immunoglobulin A expressing B cells. (1994) (17)
- The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites (2019) (17)
- Lack of the programmed death‐1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules (2016) (16)
- Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia (2019) (16)
- NF-κB and mucosal homeostasis. (2011) (16)
- Composite Thermoresponsive Hydrogel with Auranofin‐Loaded Nanoparticles for Topical Treatment of Vaginal Trichomonad Infection (2019) (15)
- Immunization of Mice with Lactobacillus casei Expressing a Beta-Intimin Fragment Reduces Intestinal Colonization by Citrobacter rodentium (2011) (15)
- A novel in vitro assay for murine haematopoietic stem cells. (1988) (13)
- 20S Proteasome as a Drug Target in Trichomonas vaginalis (2019) (13)
- Therapy for Clostridium difficile infection – any news beyond Metronidazole and Vancomycin? (2017) (12)
- Coordinate Down-regulation of Adenylyl Cyclase Isoforms and the Stimulatory G Protein (Gs) in Intestinal Epithelial Cell Differentiation* (2010) (12)
- Visualizing the enteric nervous system using genetically engineered double reporter mice: Comparison with immunofluorescence (2017) (12)
- T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling. (2021) (11)
- Validated gene expression biomarker analysis for biopsy‐based clinical trials in ulcerative colitis (2014) (10)
- Chemokine Secretion of Human Cells in Response toToxoplasma gondii Infection (1999) (10)
- Metabolomics activity screening of T cell–induced colitis reveals anti-inflammatory metabolites (2021) (10)
- Microbiota and Alcoholic Liver Disease. (2016) (9)
- Colesevelam ameliorates non-alcoholic steatohepatitis and obesity in mice (2022) (8)
- Validation of Gene Expression Biomarker Analysis for Biopsy-based Clinical Trials in Crohn's Disease (2015) (8)
- Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study (2017) (8)
- Validation of Babesia proteasome as a drug target (2018) (8)
- Lesion-Forming Bacterial Pathogen Diarrhea Caused by an Attaching/Effacing Influx Protects against Colitis-Associated CXCR2-Dependent Mucosal Neutrophil (2009) (7)
- Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions. (2014) (7)
- Differential Interleukin-8 and Nitric Oxide Production in Epithelial Cells Induced by Mucosally Invasive and Noninvasive Trypanosoma cruzi Trypomastigotes (2003) (7)
- Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis. (2021) (7)
- Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. (2020) (7)
- Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators. (2019) (6)
- TLR3 signaling is downregulated by a MAVS isoform in epithelial cells. (2016) (6)
- Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics (2022) (6)
- Co-Delivery of Antigens and Adjuvant in Polymeric Nanoparticles Coated with Native Parasite Membranes Induces Protective Mucosal Immunity against Giardia lamblia. (2022) (6)
- Implementation of Mass Cytometry as a Tool for Mechanism of Action Studies in Inflammatory Bowel Disease. (2018) (6)
- Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis (2020) (6)
- Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter (2021) (5)
- Production of MDC / CCL 22 by human intestinal epithelial cells (2001) (5)
- Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis. (2021) (5)
- Small bowel infections (2002) (5)
- Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells (2020) (4)
- Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia (2017) (4)
- CHAPTER 42 – Innate Immunity (2006) (4)
- Perspectives Series: Host/Pathogen Interactions (1997) (3)
- Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1 (2021) (3)
- Chemokine receptor CCR 6 transduces signals that activate p 130 Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells (2004) (3)
- Perturbations of multiple hemopoietic lineages in retrovirus-induced murine malignant histiocytosis. (1995) (3)
- Human intestinal epithelial cells express receptors for platelet-activating factor. (1999) (2)
- B cell dependent and independent host defenses against Giardia (2000) (2)
- IgG "detoxes" the intestinal mucosa. (2015) (2)
- Conserved metabolic enzymes as vaccine antigens for giardiasis (2022) (2)
- Cyclic AMP promotes CREB-dependent induction of the cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK (2004) (2)
- Toxin A-Induced Mucosal Injury difficile Clostridium Important Protective Role in Has an β B-Kinase κ Epithelial Cell (2006) (2)
- S1724 P53 Deficiency is Protective Against Acute Intestinal Damage Through Increased Interleukin-6 Production in a Mouse Model of Acute Colitis (2010) (2)
- Giardiasis and balantidiasis (2020) (1)
- The role of IL-6 and IL-23 in colitis associated cancer (2009) (1)
- Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation (2012) (1)
- Human intestinal xenografts as a new model for ion transport studies (2000) (1)
- PTPN2 is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice (2023) (1)
- Skin microbiome regulates SCF level in Keratinocytes and defines mast cell maturation (2018) (1)
- Human colon epithelial cells produce macrophage migration inhibitory factor, a novel regulator of inflmmation and cell growth (2001) (1)
- Regulated production of the TH2-lymphocyte chemoattractant macrophage derived chemokine (MDC) by human intestinal epithelial cells (2000) (1)
- Martin F. Kagnoff, MD: 1941–2014 (2015) (1)
- Giardia lamblia infection of human intestinal epithelial cell cultures inhibits epithelial nitric oxide production (1998) (1)
- Epithelial cell-intrinsic IKKbeta expression regulates innate and adaptive immunity in the gut (2007) (1)
- Colon epithelial cell lines express multiple chemokines (1995) (1)
- Author Correction: Sphingosine 1-phosphate modulation and immune cell trafficking in inflammatory bowel (2022) (1)
- Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia (2021) (1)
- 21 Caspase 8 Maintains Epithelial Cell Adhesion and Intestinal Homeostasis In Vivo Through Regulation of Clathrin-Dependent Endocytosis and Autophagy (2013) (1)
- Interferon (IFN)-Γ regulated production of chemoattractants specific for CD4+ memory T cells by human intestinal epithelial cells (2000) (0)
- P050 Centrally-determined standardization of flow cytometry methods reduces inter-laboratory variation in a prospective multicenter study. (2017) (0)
- Sa2045 Excitatory and Inhibitory Motor Neurons of the Esophageal Myenteric Plexus: A Study Using Genetically Altered Double Reporter Mice (2014) (0)
- The role of interleukin 23 in colitis-associated and spontaneous colon cancer: P-194. (2011) (0)
- Screening Analysis of Novel 5-Nitroimidazole Derivatives Targeting Trichomonas vaginalis Revealed Different Resistance Types (2015) (0)
- 4 Caspase 8 maintains epithelial cell adhesion and intestinal homeostasis in vivo through regulation of clathrin-dependent endocytosis and autophagy (2013) (0)
- Intestinal epithelial cells as for the natural immune watchdogs system (1995) (0)
- Attaching / Effacing Lesion-Forming Enteric Establishment of a Microbial Niche for IL-6-Dependent Mucosal Protection Prevents and (2008) (0)
- 557 Microbiome controls mast cell differentiation in the skin (2017) (0)
- Regulated and polarized nitric oxide release by human colon epithelial cells (1998) (0)
- Decreased ion transport and NKCC-1 levels in interferon-gamma treated human intestinal xenografts (2001) (0)
- Non-inflammatory small bowel infection induces colitis in mouse models of inflammatory bowel disease: O-19. (2011) (0)
- targeting of gut bacterium attenuates alcoholic liver disease. (2019) (0)
- Abstract 1438: Opposing influence of activin and TGFβ on PI3K and MEK/ERK signaling in colon cancer (2015) (0)
- Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells. (1998) (0)
- Mucosal immune system (2022) (0)
- [Hematopoietic stem cells (CFU-S) in retrovirus-induced murine malignant histiocytosis]. (1990) (0)
- Human Intestinal Epithelial Cells of Proinflammatory Cytokine Binding on The Regulation and Functional Consequence (1998) (0)
- Nasopharyngeal Carriage Streptococcus pneumoniae Protection against Receptor-Mediated Transport of IgA in An Important Role for Polymeric Ig (2004) (0)
- Notice of duplicate publication (1995) (0)
- PTPN2 Dysfunction Exacerbates C. rodentium Infection and Prevents Bacterial Clearance in a Cell‐Type Specific Manner (2020) (0)
- Cell Cycle and Senescence Nuclear Expression of b-Catenin Promotes RB Stability and Resistance to TNF-Induced Apoptosis in Colon Cancer Cells (2015) (0)
- A method of processing polyhalite for the purpose of production of langbeinite, potassium sulfate and liquid fertilizer (2007) (0)
- 149 - Gastrointestinal Microbes Enhance the Accumulation of Reactive Oxygen Species (ROS) and Dna Damage that are Regulated by Apurinic/Apyrimidinic Endonuclease 1 (APE1) (2018) (0)
- Gnas ablation in CD11c+ cells prevents high-fat diet-induced obesity by elevating adipose tissue catecholamine levels and thermogenesis (2022) (0)
- Regulated expression of a unique antimicrobial peptide, cathelicidin LL-37, by human colon epithelium (2001) (0)
- In Vivo 129 Murine Model of Salmonella Infection is a Powerful Tool to Examine Human Clinical Isolates (2012) (0)
- Epidermal growth factor receptor (EGFR) and NF-ϰB regulate intestinal epithelial restitution in a novel motogenic cascade (2003) (0)
- Sa127 AN IBD-RISK VARIANT IN PTPN2 PROMOTES CELLULAR UPTAKE OF SARS-COV-2, WHICH IS MITIGATED BY THE JAK INHIBITOR TOFACITINIB (2021) (0)
- Martin F. Kagnoff, MD, January 19, 1941--November 16, 2014. (2015) (0)
- Increased ion transport is due to upregulated cyclooxygenase activity in Salmonella infected human intestinal xenografts (2001) (0)
- Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer (2015) (0)
- 31 Development of Functional Microfold (M) Cells From Intestinal Stem Cells in Primary Human Enteroids (2016) (0)
- HT-29 human intestinal epithelial cells express mRNA and protein for tumor necrosis factor receptors I and II* (1998) (0)
- Giardia lamblia Against the Lumen-Dwelling Pathogen as Potential Determinants of Host Defense ArginineEpithelial Cells and Competition for Nitric Oxide Production by Human Intestinal (2000) (0)
- The role of IL-6 and IL-23 in colitis associated cancer (88.30) (2009) (0)
- Large Intestine Role in Maintaining Mucosal Homeostasis in the Mammalian Mediated Immune Interactions Play a Critical − Class Ib MHC (2021) (0)
- Olfactory receptor 2 (Olfr2) and its human ortholog OR6A2 expressed in macrophages drive NLRP3 inflammasome activation and exacerbate atherosclerosis in mice (2020) (0)
- permeability in mouse Peyer ' s patches by modulating T cell function and epithelial regulates the host response towards microflora Nod 2 (0)
- Notice of Duplicate Publication (2000) (0)
- Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease (2019) (0)
- Development of subunit selective substrates for Trichomonas vaginalis proteasome (2023) (0)
- Induction of chronic colitis by a protozoan non-inflammatory small bowel infection. (2011) (0)
- Against the Lumen-Dwelling Pathogen as Potential Determinants of Host Defense Arginine Epithelial Cells and Competition for Nitric Oxide Production by Human Intestinal (2000) (0)
- A novel hypomorphic Apex1 mouse model implicates apurinic-apyrimidinic endonuclease 1 in oxidative DNA damage repair in gastric epithelial cells. (2022) (0)
- Analysis using high-density CDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasiveenteric bacteria Salmonella (2000) (0)
- Centrally-Determined Standardization of Flow Cytometry Methods Reduces Inter-Laboratory Variation in a Prospective Multicenter Study (2017) (0)
- Giardia Lumen-Dwelling Protozoan Parasite Intestinal Immune Defense against the Polymeric Immunoglobulin Receptor in Svärd (2006) (0)
- Additional file 4: Table S1. of Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer (2015) (0)
- Proinflammatory functions of the receptors for thromboxane A2 and prostacyclin in experimental colitis (2001) (0)
- S1726 Cxcr2-Targeted Chemokines Are Critical Regulators of Host Defense Against the Attaching/Effecing Lesion-Forming Pathogen Citrobacter rodentium (2008) (0)
- Apoptosis of human intestinal epithelial cells induced by enteroinvasive bacteria requires bacterial entry and replication/protein synthesis but not epithelial fas expression (1998) (0)
- Acute Small Bowel Infection Induces Colitis Via CD103(‐) Antigen Presenting Cells and Th1 Responses: P‐195 (2012) (0)
- Human milk oligosaccharides reduce EPEC attachment in vitro and EPEC colonization in mice (2013) (0)
- Tu1841 Epithelial Cell Signaling as Target for Antimicrobial Therapy Against Diarrheagenic Escherichia coli - New Role for Kinase Inhibitors in Blocking Infections With Enteropathogenic E. coli (2012) (0)
- Adherent Bacterial Pathogens Defense against Colonization with Epithelial Cathelicidin Mediates Innate Intestinal (2005) (0)
- Regulated production of CCL28 by human intestinal epithelial cells (2003) (0)
- Tu1661 Activin and TGFβ Use Diverging Mitogenic Signaling in Advanced Colon Cancer (2014) (0)
- Novel model of colitis induced by a non-inflammatory small bowel infection (166.10) (2011) (0)
- Sa528 PTPN2 DYSFUNCTION EXACERBATES C. RODENTIUM INFECTION AND PREVENTS BACTERIAL CLEARANCE IN A CELL-TYPE SPECIFIC MANNER (2021) (0)
- Class Ib MHC–Mediated Immune Interactions Play a Critical Role in Maintaining Mucosal Homeostasis in the Mammalian Large Intestine (2021) (0)
- Human intestinal epithelium expresses EBI3, a potential modulator of the IL-12 response (2001) (0)
- Thromboxane A2 receptor regulates the severity of experimental murine colitis (94.30) (2009) (0)
- Epithelial cell-intrinsic IKKβ expression regulates innate and adaptive immunity in the gut (42.4) (2007) (0)
- Su1858 Motor Neurons of Gut Myenteric Plexus: Visualization by Genetic and Immunohistochemical Method (2015) (0)
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What Schools Are Affiliated With Lars Eckmann?
Lars Eckmann is affiliated with the following schools:
