Lars Farde
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Researcher ORCID ID = 0000-0003-1297-0816
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(Suggest an Edit or Addition)Lars Farde's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. (1992) (1360)
- Quantitative analysis of D2 dopamine receptor binding in the living human brain by PET. (1986) (854)
- Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers (1999) (733)
- The correlative triad among aging, dopamine, and cognition: Current status and future prospects (2006) (683)
- Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs. (1988) (663)
- Changes in Cortical Dopamine D1 Receptor Binding Associated with Cognitive Training (2009) (545)
- Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients (1993) (518)
- D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride. (1990) (515)
- A PET study of (2000) (515)
- Age-related cognitive deficits mediated by changes in the striatal dopamine system. (2000) (469)
- Kinetic Analysis of Central [11C]Raclopride Binding to D2-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis (1989) (463)
- Distribution of D1- and D2-Dopamine Receptors, and Dopamine and Its Metabolites in the Human Brain (1994) (399)
- Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain (2000) (365)
- D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients. (1995) (340)
- Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography. (1985) (307)
- No D2 receptor increase in PET study of schizophrenia. (1987) (297)
- Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]WAY-100635 (1997) (287)
- Transplantation in Parkinson's disease: Two cases of adrenal medullary grafts to the putamen (1987) (274)
- Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients. (1999) (253)
- The role of the striatal dopamine transporter in cognitive aging (2005) (251)
- PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease. (1997) (246)
- Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding. (2006) (230)
- Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors. (1995) (229)
- Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: Association between striatal dopamine markers and motor hyperactivity (2005) (228)
- D2 dopamine receptors and personality traits (1997) (225)
- Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes. (1997) (223)
- Meta-analysis of cognitive performance in drug-naïve patients with schizophrenia (2014) (217)
- The serotonin system and spiritual experiences. (2003) (214)
- Common brain disorders are associated with heritable patterns of apparent aging of the brain (2019) (213)
- Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia. (2002) (200)
- Clinical Validation of 18F-AZD4694, an Amyloid-β–Specific PET Radioligand (2012) (193)
- Imaging of neurotransmitter receptors in the living human brain. (1986) (192)
- Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT (2009) (189)
- A PET-study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients (1997) (188)
- Pet study of [11C] β‐CIT binding to monoamine transporters in the monkey and human brain (1994) (181)
- Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography. (1986) (174)
- Imaging of [11C]-labelled Ro 15-1788 binding to benzodiazepine receptors in the human brain by positron emission tomography. (1985) (174)
- Quantification of [11C]FLB 457 Binding to Extrastriatal Dopamine Receptors in the Human Brain (1999) (173)
- Variability in D2‐dopamine receptor density and affinity: A PET study with [11C]raclopride in man (1995) (173)
- PET study of D(1) dopamine receptor binding in neuroleptic-naive patients with schizophrenia. (2002) (173)
- Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy (2004) (172)
- Autoradiographic localization of extrastriatal D2‐dopamine receptors in the human brain using [125I]epidepride (1996) (169)
- Comparison of the Transient Equilibrium and Continuous Infusion Method for Quantitative PET Analysis of [11C]Raclopride Binding (1998) (167)
- Using positron emission tomography to facilitate CNS drug development. (2006) (159)
- Positron Emission Tomography Studies on D2 and 5‐HT2 Receptor Binding in Risperidone‐Treated Schizophrenic Patients (1995) (158)
- Antipsychotic Occupancy of Dopamine Receptors in Schizophrenia (2011) (156)
- Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. (2015) (154)
- Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain. (2001) (153)
- D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics (2004) (151)
- PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride (2004) (150)
- D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. (1995) (146)
- No elevated D2 dopamine receptors in neuroleptic-naive schizophrenic patients revealed by positron emission tomography and [11C]N-methylspiperone (1995) (145)
- A PET Study of 5-HT2 and D2 Dopamine Receptor Occupancy Induced by Olanzapine in Healthy Subjects (1997) (138)
- Preparation of 11C-labelled Raclopride, a new potent dopamine receptor antagonist: preliminary PET studies of cerebral dopamine receptors in the monkey. (1985) (137)
- PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907. (1998) (134)
- Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man. (1998) (133)
- Visualization of the Dopamine Transporter in the Human Brain Postmortem with the New Selective Ligand [125I]PE2I (1999) (129)
- Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors. (1998) (128)
- Characterization of AZD4694, a novel fluorinated Aβ plaque neuroimaging PET radioligand (2010) (126)
- Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907 (1996) (126)
- Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia. (2004) (125)
- Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: a PET study with [11C]FLB 457. (2003) (121)
- AZD2184: a radioligand for sensitive detection of β‐amyloid deposits (2009) (121)
- PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain (2004) (119)
- Brain radioligands--state of the art and new trends. (2001) (118)
- Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson’s disease (2000) (116)
- Autoradiographic localization of 5‐HT2A receptors in the human brain using [3H]M100907 and [11C]M100907 (2000) (115)
- Performance Evaluation of the Small-Animal nanoScan PET/MRI System (2013) (115)
- Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride (2006) (114)
- Chemical brain anatomy in schizophrenia (1995) (114)
- Raclopride, a new selective ligand for the dopamine-D2 receptors (1988) (112)
- Effect of reserpine‐induced depletion of synaptic dopamine on [11C]Raclopride binding to D2‐dopamine receptors in the monkey brain (1997) (112)
- Thinking Outside a Less Intact Box: Thalamic Dopamine D2 Receptor Densities Are Negatively Related to Psychometric Creativity in Healthy Individuals (2010) (111)
- Dopamine D1 receptors and age differences in brain activation during working memory (2011) (110)
- Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans. (2009) (110)
- Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET. (1999) (104)
- Extrastriatal dopamine D2 receptor binding modulates intraindividual variability in episodic recognition and executive functioning (2009) (104)
- Test–retest reproducibility of [11C]PBR28 binding to TSPO in healthy control subjects (2015) (103)
- Dopamine and cognitive functioning: brain imaging findings in Huntington's disease and normal aging. (2001) (102)
- Comparison of the In Vitro Receptor Binding Properties of N‐[3H]Methylspiperone and [3H]Raclopride to Rat and Human Brain Membranes (1990) (102)
- Potentials and Pitfalls Using High Affinity Radioligands in PET and SPET Determinations on Regional Drug Induced D2 Receptor Occupancy—A Simulation Study Based on Experimental Data (2001) (102)
- PET studies with carbon-11 radioligands in neuropsychopharmacological drug development. (2001) (101)
- No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457. (2001) (101)
- Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28 (2017) (100)
- Differentiation of extrastriatal dopamine D2 receptor density and affinity in the human brain using PET (2004) (99)
- Quantification of 11C-MADAM binding to the serotonin transporter in the human brain. (2005) (99)
- The advantage of using positron emission tomography in drug research (1996) (98)
- Stereoselective binding of 11C-raclopride in living human brain — a search for extrastriatal central D2-dopamine receptors by PET (2004) (97)
- PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor (2005) (96)
- Individual differences in the proneness to have flow experiences are linked to dopamine D2-receptor availability in the dorsal striatum (2013) (96)
- [11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography. (1996) (96)
- PET Analysis Indicates Atypical Central Dopamine Receptor Occupancy in Clozapine-Treated Patients (1992) (96)
- Saturation analysis of specific 11C Ro 15‐1788 binding to the human neocortex using positron emission tomography (1989) (94)
- Time course of D2-dopamine receptor occupancy examined by PET after single oral doses of haloperidol (2005) (93)
- Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling. (1998) (93)
- 5-HT2 and D2 dopamine receptor occupancy in the living human brain (1993) (91)
- Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease (1997) (91)
- Lack of apparent antipsychotic effect of the D1-dopamine recepotr antagonist SCH39166 in acutely ill schizophrenic patients (1995) (91)
- Measurement of Methylphenidate-Induced Change in Extrastriatal Dopamine Concentration using [11C]FLB 457 PET (2007) (90)
- D1-, D2-, and 5-HT2-receptor occupancy in clozapine-treated patients. (1994) (90)
- Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET. (1996) (88)
- Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method. (2011) (88)
- Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique. (1999) (88)
- [11C] beta-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations. (1993) (87)
- Radioligand Disposition and Metabolism — Key Information in Early Drug Development (1995) (87)
- Imaging the living human brain: magnetic resonance imaging and positron emission tomography. (1997) (86)
- Detection of amyloid in Alzheimer’s disease with positron emission tomography using [11C]AZD2184 (2009) (85)
- A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey. (2005) (85)
- Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects (2012) (85)
- Workshop on schizophrenia, PET, and dopamine D2 receptors in the human neostriatum. (1988) (84)
- Changes in striatal D2‐receptor density following chronic treatment with amphetamine as assessed with pet in nonhuman primates (1999) (84)
- The immune response of the human brain to abdominal surgery (2017) (82)
- [11C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain (2003) (82)
- [11C]AZ10419369: A selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain (2008) (79)
- [11C]β‐CIT‐FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography (1996) (79)
- Effect of a single dose of escitalopram on serotonin concentration in the non-human and human primate brain. (2013) (77)
- Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER. (2003) (77)
- Plasma prolactin and central D2 receptor occupancy in antipsychotic drug-treated patients. (1998) (77)
- Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum (2008) (77)
- PET-characterization of [carbonyl-11C]WAY-100635 binding to 5-HT1A receptors in the primate brain (1997) (76)
- Whole hemisphere autoradiography of the postmortem human brain. (1998) (76)
- Iodine-123 labeled nor-β-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography (1997) (74)
- Quantitative Analysis of [11C]AZ10419369 Binding to 5-HT1B Receptors in Human Brain (2011) (74)
- PET analysis of central [11 C]raclopride binding in healthy young adults and schizophrenic patients—reliability and age effects (1992) (74)
- Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man (1995) (74)
- Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography (2006) (74)
- The role of dopamine systems in cognitive aging (2005) (73)
- [11C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET (2005) (71)
- Nigrostriatal dopamine transporter availability in early Parkinson's disease (2018) (70)
- Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy. (2005) (70)
- [18F]Flumazenil binding to central benzodiazepine receptor studies by PET – Quantitative analysis and comparisons with [11C]flumazenil – (2009) (69)
- Reproducibility of [11C]FLB 457 binding in extrastriatal regions (2001) (69)
- A comparative PET-study of five carbon-11 or fluorine-18 labelled salicylamides. Preparation and in vitro dopamine D-2 receptor binding. (1991) (68)
- Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study (2006) (68)
- Wavelet-Aided Parametric Mapping of Cerebral Dopamine D2 Receptors Using the High Affinity PET Radioligand [11C]FLB 457 (2002) (68)
- Measurement of Striatal and Extrastriatal Dopamine Transporter Binding with High-Resolution PET and [11C]PE2I: Quantitative Modeling and Test—Retest Reproducibility (2008) (68)
- PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects (2002) (67)
- [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations. (1995) (66)
- PET Mapping of Extrastriatal D2-like Dopamine Receptors in the Human Brain Using an Anatomic Standardization Technique and [11C]FLB 457 (1999) (66)
- Dopamine D1 receptor associations within and between dopaminergic pathways in younger and elderly adults: links to cognitive performance. (2011) (65)
- Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2 (2006) (64)
- Positron Emission Tomography of in-vivo Binding Characteristics of Atypical Antipsychotic Drugs (1996) (63)
- Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2 (2005) (62)
- Effect of amphetamine on extrastriatal D2 dopamine receptor binding in the primate brain: A PET study (2000) (62)
- Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study (2010) (62)
- A PET study of D1-like dopamine receptor ligand binding (1999) (61)
- Simulating Neurocognitive Aging: Effects of a Dopaminergic Antagonist on Brain Activity During Working Memory (2010) (61)
- Positron emission tomography finding of a high striatal D2 receptor occupancy in olanzapine-treated patients. (1998) (60)
- An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET (2004) (60)
- Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs (2020) (59)
- Reduced 5-HT1B receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder (2014) (58)
- High 5HT2A receptor occupancy in M100907-treated schizophrenic patients (2000) (58)
- [18F]β-CIT-FP is superior to [11C]β-CIT-FP for quantitation of the dopamine transporter (1997) (58)
- Fenfluramine‐induced serotonin release decreases [11C]AZ10419369 binding to 5‐HT1B‐receptors in the primate brain (2010) (58)
- Application of cross-species PET imaging to assess neurotransmitter release in brain (2015) (58)
- Human dopamine receptor subtypes—in vitro binding analysis using3H-SCH 23390 and3H-raclopride (2005) (57)
- [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo (1998) (57)
- Pharmacological Characterization ofN,N-Dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a Ligand of the Serotonin Transporter with High Affinity and Selectivity (2003) (56)
- Genetic Variation in Brain-Derived Neurotrophic Factor Is Associated with Serotonin Transporter but Not Serotonin-1A Receptor Availability in Men (2009) (56)
- Delayed normalization of central D2 dopamine receptor availability after discontinuation of haloperidol decanoate. Preliminary findings. (1997) (56)
- Association between a promoter dopamine D2 receptor gene variant and the personality trait detachment (2003) (55)
- PET analysis of [11C]flumazenil binding to benzodiazepine receptors in chronic alcohol-dependent men and healthy controls (1993) (55)
- A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635 (2006) (55)
- [11C]Vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies (2005) (53)
- Metabolism of the PET ligand [11C]SCH 23390. Identification of two radiolabelled metabolites with HPLC (1994) (53)
- Distribution of remoxipride to the human brain and central D2‐ dopamine receptor binding examined in vivo by PET (1990) (52)
- In vitro and in vivo characterisation of nor-β-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain (1997) (52)
- QTc interval prolongation and antipsychotic drug treatments: focus on sertindole. (2005) (52)
- Measurement of serotonin transporter binding with PET and [11C]MADAM: A test–retest reproducibility study (2006) (51)
- Dopamine D1 receptor number — a sensitive PET marker for early brain degeneration in Huntington's disease (2005) (50)
- Radioligands for the study of brain 5-HT(1A) receptors in vivo--development of some new analogues of way. (2000) (49)
- NURR1 promoter polymorphisms: Parkinson's disease, schizophrenia, and personality traits (2003) (49)
- Maps of receptor binding parameters in the human brain — a kinetic analysis of PET measurements (2004) (49)
- Dopamine D2 receptor density in the limbic striatum is related to implicit but not explicit movement sequence learning (2010) (49)
- Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability (2010) (49)
- Central D1- and D2-receptor occupancy during antipsychotic drug treatment (1990) (48)
- Pindolol binding to 5-HT1A receptors in the human brain confirmed with positron emission tomography (1999) (48)
- PET measurement of serotonin transporter occupancy: a comparison of escitalopram and citalopram. (2007) (48)
- Brain imaging of schizophrenia—the dopamine hypothesis (1997) (47)
- Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET. (1990) (47)
- High 5-HT2 receptor occupancy in clozapine treated patients demonstrated by PET (2005) (47)
- Diurnal and seasonal variation of the brain serotonin system in healthy male subjects (2015) (47)
- In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects (2016) (47)
- Low striatal and extra-striatal D2 receptor occupancy during treatment with the atypical antipsychotic sertindole (2002) (46)
- A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635 (2006) (46)
- Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study (2019) (46)
- Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain. (1998) (45)
- Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine (2002) (44)
- PET imaging of [11C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding (2018) (44)
- The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain. (2002) (44)
- Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET study (2003) (43)
- Selective D1- and D2-dopamine receptor blockade both induces akathisia in humans — a PET study with [11C]SCH 23390 and [11C]raclopride (2005) (43)
- Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging (1998) (43)
- CSF GABA is reduced in first-episode psychosis and associates to symptom severity (2017) (42)
- Dopamine D1-receptor binding in the living human brain. (1986) (42)
- A PET study on regional coexpression of 5-HT1A receptors and 5-HTT in the human brain (2007) (42)
- Error Analysis for Quantification of [11C]FLB 457 Binding to Extrastriatal D2 Dopamine Receptors in the Human Brain (2001) (42)
- [125I]β-CIT-FE and [125I]β-CIT-FP are superior to [125I]β-CIT for dopamine transporter visualization: Autoradiographic evaluation in the human brain (1997) (42)
- Implications of brain imaging for the management of schizophrenia (1998) (42)
- A PET study of D(1)-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain. (1999) (41)
- Dopamine D2/3 receptor occupancy of apomorphine in the nonhuman primate brain—A comparative PET study with [11C]raclopride and [11C]MNPA (2009) (41)
- Modeling of PET data in CNS drug discovery and development (2013) (41)
- Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder (2012) (40)
- Test-retest reliability of central [11C]raclopride binding at high D2 receptor occupancy. A PET study in haloperidol-treated patients (1996) (40)
- Modulation of striatal dopamine D1 binding by cognitive processing (2009) (39)
- A Comparison of Gray Matter Density in Restless Legs Syndrome Patients and Matched Controls Using Voxel‐Based Morphometry (2010) (39)
- Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development. (2000) (38)
- Quantification of serotonin transporter availability with [11C]MADAM — A comparison between the ECAT HRRT and HR systems (2010) (38)
- [11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey. (1993) (37)
- Synthesis of carbon-11 labelled SCH 39166, a new selective dopamine D-1 receptor ligand, and preliminary PET investigations. (1991) (37)
- Applications of a computerized adjustable brain atlas in positron emission tomography. (1986) (37)
- Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [11C]PBR28 HRRT PET study (2019) (37)
- Confirmation of Fenfluramine Effect on 5-HT1B Receptor Binding of [11C]AZ10419369 using an Equilibrium Approach (2012) (35)
- Quantification of serotonin transporter availability with [11C]MADAM — A comparison between the ECAT HRRT and HR systems (2010) (35)
- Dopamine D1 receptor availability is related to social behavior: A positron emission tomography study (2014) (35)
- Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates (2015) (34)
- Clozapine binds preferentially to cortical D1-like dopamine receptors in the primate brain: a PET study (2006) (34)
- PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain. (2008) (34)
- Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data (2017) (34)
- GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models (2018) (34)
- Non-equipotent doses partly explain differences among antipsychotics – implications of PET studies (2000) (33)
- Muscle biopsy findings, conduction velocity and refractory period of single motor nerve fibres in schizophrenia. (1987) (33)
- Brain Uptake and Plasma Metabolism of [11C]Vinpocetine: A Preliminary PET Study in a Cynomolgus Monkey (1999) (33)
- Comparison of D2 dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects (2011) (32)
- [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. (2003) (32)
- Mapping of Central D2Dopamine Receptors in Man Using [11C]Raclopride: PET with Anatomic Standardization Technique (1999) (31)
- Pharmacokinetics and dopamine d2 and serotonin 5-ht2a receptor occupancy of paliperidone in healthy subjects: two open-label, single-dose studies (PAL-115) (2007) (31)
- Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter — Application to juvenile myoclonic epilepsy (2012) (31)
- Radiosynthesis of the candidate β‐amyloid radioligand [11C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys (2010) (31)
- PIII‐57 (2006) (31)
- An open clinical and biochemical study of ritanserin in acute patients with schizophrenia (1994) (31)
- Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain (2019) (30)
- Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [ 11 C ]RGH-1756 in the monkey brain (2004) (30)
- PET study of the M1-agonists [11C]xanomeline and [11C]butylthio-TZTP in monkey and man. (1996) (30)
- Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain (2003) (30)
- A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer (2020) (30)
- Preparation of [76Br]FLB 457 and [76Br]FLB 463 for examination of striatal and extrastriatal dopamine D-2 receptors with PET. (1996) (29)
- Test–retest reliability of [11C]AZ10419369 binding to 5-HT1B receptors in human brain (2014) (28)
- Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study. (2020) (28)
- Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR. (2013) (28)
- Decreased thalamic D 2 / D 3 receptor binding in drug-naive patients with schizophrenia : a PET study with [ 11 C ] FLB 457 (2003) (28)
- Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds. (2011) (28)
- Quantitative Analysis of 18F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4′-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease (2015) (28)
- Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369 (2011) (28)
- The International Journal of Neuropsychopharmacology. (1998) (27)
- Effect of clozapine and risperidone on 5-HT2 and D2-dopamine receptor binding in the post-mortem human brain. An autoradiographic study (1995) (27)
- Search for correlations between serotonin 5-HT1A receptor expression and cognitive functions—a strategy in translational psychopharmacology (2006) (27)
- Radiosynthesis and autoradiographic evaluation of [11C]NAD-299, a radioligand for visualization of the 5-HT1A receptor. (1999) (27)
- Extrastriatal dopamine D2 receptor binding in Huntington's disease (2011) (27)
- [11C]Ro 15-4513, a ligand for visualization of benzodiazepine receptor binding (1992) (27)
- Evaluation of Two Automated Methods for PET Region of Interest Analysis (2014) (26)
- Quantification of Blood Flow-Dependent Component in Estimates of Beta-Amyloid Load Obtained Using Quasi-Steady-State Standardized Uptake Value Ratio (2015) (26)
- Improved mapping and quantification of serotonin transporter availability in the human brainstem with the HRRT (2012) (26)
- Quantitative analysis of 18F-FE-PE2I binding to the dopamine transporter in Parkinson’s disease (2015) (26)
- New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey. (2001) (26)
- PET examination of central D2 dopamine receptor occupancy in relation to extrapyramidal syndromes in patients being treated with neuroleptic drugs. (1993) (26)
- Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease (2014) (25)
- Identification of positron emission tomography (PET) tracer candidates by prediction of the target-bound fraction in the brain (2014) (25)
- Relationship of dopamine D1 receptor binding in striatal and extrastriatal regions to cognitive functioning in healthy humans (2011) (25)
- PET imaging of neuroreceptors in schizophrenia (1995) (25)
- Arterial Input Function Derived from Pairwise Correlations Between PET-image Voxels (2013) (25)
- D2 occupancy, extrapyramidal side effects and antipsychotic drug treatment: a pilot study with sertindole in healthy subjects (1997) (25)
- PET-Determination of Robalzotan (NAD-299) Induced 5-HT1A Receptor Occupancy in the Monkey Brain (2000) (25)
- Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain (2017) (25)
- SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study (2013) (24)
- Ligand metabolites in plasma during PET‐studies with the 11C‐labelled dopamine antagonists, raclopride, SCH 23390 and N‐methylspiroperidol (1992) (24)
- Lipophilic metabolite of [123I]β‐CIT in human plasma may obstruct quantitation of the dopamine transporter (1995) (24)
- Characterization of C‐11 or I‐123 Labelled β‐CIT‐FP and β‐CIT‐FE Metabolism Measured in Monkey and Human Plasma. Identification of Two Labelled Metabolites with HPLC (1996) (24)
- Characterization of bromine-76-labelled 5-bromo-6-nitroquipazine for PET studies of the serotonin transporter. (1999) (24)
- PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter. (1999) (24)
- Effects of amphetamine on the human brain opioid system – a positron emission tomography study (2012) (24)
- Dopamine receptors in schizophrenia (1996) (24)
- Test-retest reproducibility of dopamine D2/3 receptor binding in human brain measured by PET with [11C]MNPA and [11C]raclopride (2013) (23)
- GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans (2016) (23)
- Central 5-HT2A and D2 dopamine receptor occupancy after sublingual administration of ORG 5222 in healthy men (1997) (23)
- Brain Dopaminergic Systems: Imaging with Positron Tomography (2012) (23)
- Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors. (1999) (22)
- Test-retest reliability and convergent validity of (R)-[11C]PK11195 outcome measures without arterial input function (2018) (22)
- Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography. (2000) (22)
- D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients (2019) (22)
- A PET study of [11C]β-CIT-FE binding to the dopamine transporter in the monkey and human brain (2000) (22)
- Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits (2003) (22)
- Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. (2015) (22)
- Brain neuroreceptor density and personality traits: towards dimensional biomarkers for psychiatric disorders (2018) (22)
- Age-related loss of olfactory sensitivity: Association to dopamine transporter binding in putamen (2009) (22)
- Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane. (1994) (21)
- 18F-MCL-524, an 18F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study (2014) (21)
- Quantitative PET Analysis of the Dopamine D2 Receptor Agonist Radioligand 11C-(R)-2-CH3O-N-n-Propylnorapomorphine in the Human Brain (2009) (21)
- Reliability of volumetric and surface-based normalisation and smoothing techniques for PET analysis of the cortex: A test-retest analysis using [11C]SCH-23390 (2017) (21)
- Utilization of radioligands in schizophrenia research. (1995) (21)
- Palladium mediated ¹¹C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [¹¹C]AZD9272. (2013) (20)
- The genetic architecture of human brainstem structures and their involvement in common brain disorders (2019) (20)
- PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter. (2002) (20)
- Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer’s disease patients (2013) (20)
- PET Studies on Brain Energy Metabolism and Dopamine Receptors in Schizophrenic Patients and Monkeys (1985) (20)
- The new selective D2-dopamine receptor antagonist raclopride--pharmacokinetics, safety and tolerability in healthy males. (1989) (20)
- Quantitative Analysis of Amyloid Deposition in Alzheimer Disease Using PET and the Radiotracer 11C-AZD2184 (2014) (20)
- Brain exposure of the ATM inhibitor AZD1390 in humans - a positron emission tomography (PET) study. (2020) (20)
- D(2)- and 5-HT(2) receptor occupancy in high-dose neuroleptic-treated patients. (1998) (20)
- Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET (2003) (20)
- 5‐HT1B receptor imaging and cognition: A positron emission tomography study in control subjects and parkinson's disease patients (2015) (20)
- The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo. (2004) (19)
- Transcription factor AP-2β genotype, striatal dopamine D2 receptor density and cerebrospinal fluid monoamine metabolite concentrations in humans (2004) (19)
- Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: A PET study in nonhuman primate brain using ( S , S )-[18F]FMeNER-D2 (2006) (19)
- Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using 18F-FE-PE2I in Healthy Controls and Parkinson Disease Patients (2016) (19)
- PET studies of D2‐receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans (2010) (19)
- 11C-carbonylation reactions using gas–liquid segmented microfluidics (2015) (19)
- Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions. (1999) (19)
- PET STUDIES OF DOPAMINE RECEPTORS IN RELATION TO ANTIPSYCHOTIC DRUG TREATMENT (1992) (19)
- N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists. (2005) (18)
- Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder (2016) (18)
- Support for limited brain availability of tyrosine in patients with schizophrenia. (2005) (18)
- Oral administration of NNC 756 — a placebo controlled PET study of D1-dopamine receptor occupancy and pharmacodynamics in man (1995) (18)
- Amphetamine Decreases α2C-Adrenoceptor Binding of [11C]ORM-13070: A PET Study in the Primate Brain (2015) (18)
- Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. (2007) (18)
- Serotonin transporter availability in adults with autism—a positron emission tomography study (2020) (18)
- A cross-validation study on the relationship between central D2 receptor occupancy and serum perphenazine concentration (2004) (17)
- Synthesis and Positron Emission Tomography Evaluation of Three Norepinephrine Transporter Radioligands: [C-11]Desipramine, [C-11]Talopram and [C-11]Talsupram (2005) (17)
- The MINDVIEW project: First results (2018) (17)
- NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo (2011) (17)
- Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756 (2005) (17)
- Positron Emission Tomography in Schizophrenia (1990) (16)
- Central D2 receptor occupancy and effects of zuclopenthlxol acetate in humans (1995) (16)
- Neurotransmitter receptor imaging in Alzheimer's disease. (1987) (16)
- Synthesis of ([(11)C]carbonyl)raclopride and a comparison with ([(11)C]methyl)raclopride in a monkey PET study. (2015) (16)
- Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [11C]PBR28 positron emission tomography (2019) (16)
- The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass (2018) (16)
- Distinct regional age effects on [11C]AZ10419369 binding to 5-HT1B receptors in the human brain (2014) (16)
- New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey. (2004) (15)
- Positron Emission Tomography Studies on Dopamine Receptors in Schizophrenia (1995) (15)
- Distinct binding of amyloid imaging ligands to unique amyloid‐β deposited in the presubiculum of Alzheimer's disease (2015) (15)
- Synthesis and PET evaluation of (R)‐[S‐methyl‐11C]thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters (2006) (15)
- Effect of risperidone on high-affinity state of dopamine D2 receptors: a PET study with agonist ligand [11C](R)-2-CH3O-N-n-propylnorapomorphine. (2011) (15)
- Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study. (2002) (15)
- Positron emission tomography--examination of chemical transmission in the living human brain. Development of radioligands. (1992) (15)
- Syntheses of [123I]-, [125I]- and unlabelled (S)-3-iodo-5,6-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]salicylamide (NCQ 298), selective ligands for the study of dopamine D-2 receptors. (1990) (15)
- [18F] beta-CIT-FP is superior to [11C] beta-CIT-FP for quantitation of the dopamine transporter. (1997) (15)
- 11C-SCH 39166, a selective ligand for visualization of dopamine-D1 receptor binding in the monkey brain using PET (2005) (15)
- Recent developments in PET scan imaging of neuroreceptors in schizophrenia. (1995) (15)
- Age-related diurnal effect on D2 receptor binding: a preliminary PET study. (2008) (15)
- P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects (2008) (14)
- Remoxipride — a new potential antipsychotic drug (1988) (14)
- PET scanning--a new tool in clinical psychopharmacology. (1988) (14)
- Increased number of monocytes and plasma levels of MCP‐1 and YKL‐40 in first‐episode psychosis (2018) (14)
- Preparation and preliminary positron emission tomography studies of 11C-Ro 15-1788, a selective benzodiazepine receptor antagonist. (1984) (14)
- Serotonin concentration enhancers at clinically relevant doses reduce [11C]AZ10419369 binding to the 5-HT1B receptors in the nonhuman primate brain (2018) (13)
- Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer’s disease (2000) (13)
- Occupancy of the central benzodiazepine receptors during benzodiazepine treatment determined by PET (1991) (13)
- Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate. (2013) (13)
- Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M1 and M2 muscarinic acetylcholine receptors in Alzheimer’s disease (1999) (13)
- Pharmacokinetics of Raclopride Formulations (1992) (13)
- [11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey. (1996) (13)
- Evaluation of SCH 39166 as PET ligand for central D1 dopamine receptor binding and occupancy in man (1995) (13)
- [11C]beta-CIT-FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography. (1996) (13)
- Preparation of [1-11C]dopamine, [1-11C]p-tyramine and [1-11C]m-tyramine. Autoradiography and PET examination of [1-11C]dopamine in primates. (1993) (12)
- 11C- and 76Br-labelled NNC 22-0010, selective dopamine D1 receptor radioligands for PET. (1996) (12)
- Quantitative analysis of ( 11 C)AZ10419369 binding to 5-HT 1B receptors in human brain (2011) (12)
- Development of 123I-labelled NNC 13-8241 as a radioligand for SPECT visualization of benzodiazepine receptor binding. (1996) (12)
- Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain (2016) (12)
- Central Benzodiazepine Receptor Binding Studied with 11-C Labelled Ro 15-1788 and Positron Emission Tomography (1986) (12)
- SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP (2001) (12)
- Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11C]PBR28 and Machine Learning Analysis (2021) (12)
- Investigation of the Metabolites of (S,S)-[11C]MeNER in Humans, Monkeys and Rats (2008) (12)
- A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers (2013) (12)
- The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain (2018) (11)
- Guidelines for biological Treatment of Schizophrenia, : Part 1: Acute Treatment of Schizophrenia and Part 2: Long-term Treatment of Schizophrenia (2005) (11)
- 505 D1-Dopamine receptors in schizophrenia examined by pet (1997) (11)
- Bromine-76 and carbon-11 labelled NNC 13-8199, metabolically stable benzodiazepine receptor agonists as radioligands for positron emission tomography (PET) (1997) (11)
- The dopamine D1 receptor agonist (S)‐[11C]N‐methyl‐NNC 01‐0259 is not sensitive to changes in dopamine concentration—a positron emission tomography examination in the monkey brain (2013) (11)
- ドーパミンD‐2受容体の研究のための選択的リガンドである,(S)‐3‐ヨウ化‐5,6‐ジメトキシ‐N‐[(1‐エチル‐2‐ピロリジニル)メチル]サリチルアミド(NCQ298)と,その〔123I〕,〔125I〕ラベル化物の合成 (1990) (10)
- The relevance of serotonergic mechanisms in the treatment of schizophrenia has not been confirmed (1997) (10)
- A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates (2016) (10)
- Radiochemical labelling of the dopamine D3 receptor ligand RGH‐1756 (2000) (10)
- Short communication Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-( 18 F)FMeNER-D 2 (2005) (10)
- Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [18F]FDG-μPET Study (2017) (10)
- P.1.c.022 PET-measured D2, 5-HT2, and norepinephrine transporter (NET) occupancy by quetiapine and N-desalkyl-quetiapine in non-human primates (2007) (10)
- Synthesis of [ethyl‐18F]fluororaclopride for the in vivo study of dopamine D2 receptors using PET (1989) (10)
- Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [11C]AZD4694 in Nonhuman Primates (2014) (10)
- Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator (2019) (10)
- PET-determination of benzodiazepine receptor binding in studies on alcoholism. (1994) (10)
- Stereoselective binding of 11C‐labelled piquindone (Ro 22–1319) to dopamine‐D2 receptors in the living human brain (1987) (10)
- [125I] beta-CIT-FE and [125I] beta-CIT-FP are superior to [125I] beta-CIT for dopamine transporter visualization: autoradiographic evaluation in the human brain. (1997) (9)
- Xanomeline, A Specific M1 Agonist: Early Clinical Studies (1994) (9)
- PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor. (2002) (9)
- [11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis (2018) (9)
- Imaging of dopamine receptors using PET and SPECT (1992) (9)
- The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans (2020) (9)
- Radiosynthesis and evaluation of new α1-adrenoceptor antagonists as PET radioligands for brain imaging. (2013) (9)
- Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [11C]MADAM PET study (2015) (9)
- Mesial temporal lobe epilepsy is associated with limbic reductions in serotonin 5HT1A receptor binding (2001) (9)
- Synthesis of 2β‐carbomethoxy‐3β‐(4‐[76Br]bromophenyl)tropane ([76Br]β‐CBT), a pet tracer for in vivo imaging of the dopamine uptake sites (1995) (9)
- Kinfitr – an open source tool for reproducible PET modelling: validation and evaluation of test-retest reliability (2020) (8)
- Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor. (2016) (8)
- High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson’s disease cohort (2020) (8)
- Effects of cocaine on [11C]norepinephrine and [11C]β-CIT uptake in the primate peripheral organs measured by PET (1996) (8)
- [11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors. (2008) (8)
- Characterization of [11C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain (2016) (8)
- Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: Validation using postmortem autoradiography data (2016) (8)
- Development of radioligands for the dopamine transporter (1996) (8)
- Brain Dopamine Receptors in Schizophrenia: PET Problems-Reply (1988) (8)
- Initial human studies with single-photon emission tomography using iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine (NNC 13-8241) (1996) (8)
- The metabolite pattern of [123I]β-CIT determined with a gradient HPLC method (1995) (8)
- Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with11C-labelled osimertinib (2018) (8)
- Clinical melperone treatment blocks D2‐dopamine receptors in the human brain as determined by PET (1989) (8)
- Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: A PET study of within-subject correlations with [11C]FLB 457 (2020) (8)
- [11C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors. (2017) (8)
- Joint explorative analysis of neuroreceptor subsystems in the human brain: application to receptor–transporter correlation using PET data (2004) (7)
- Half-life of receptor occupancy--a meaningless concept. (2005) (7)
- Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain. (2002) (7)
- Quantitative determination of D2 dopamine receptor characteristics in healthy human subjects and psychiatric patients. (1987) (7)
- Fluorine-18-labelled NCQ 115, a selective dopamine D-2 receptor ligand. Preparation and positron emission tomography. (1994) (7)
- Two C-Methyl Derivatives of [11C]WAY-100635 – Effects of an Amido α-Methyl Group on Metabolism and Brain 5-HT1A Receptor Radioligand Behavior in Monkey* (2005) (7)
- Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients (2018) (7)
- Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain (2019) (7)
- Short Communication Fenfluramine-Induced Serotonin Release Decreases ( 11 C)AZ10419369 Binding to 5-HT 1B -Receptors in the Primate Brain (2010) (7)
- Recent advances in psychiatric brain imaging. (1990) (7)
- STUDIES OF SCHIZOPHRENIA WITH POSITRON CT (1984) (7)
- Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study (2017) (7)
- [11C]NNC 22-0215, a metabolically stable dopamine D1 radioligand for PET. (1998) (6)
- PET for drug development. (2004) (6)
- Use of graphical techniques for error evaluation (1987) (6)
- Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo (2020) (6)
- Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis (2021) (6)
- Influence of rate of administration of raclopride on akathisia and prolactin response (1994) (6)
- Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain (2019) (6)
- Positron emission tomography shows high specific uptake of racemic carbon-11 labelled norepinephrine in the primate heart (1994) (6)
- P76.72 A PET and MRI Study Exploring Osimertinib Brain Exposure and Efficacy in EGFRm NSCLC CNS Metastases (2021) (6)
- Evaluation and metabolite studies of 125I- and 123I-labelled E-(R,R)-IQNP: potential radioligands for visualization of M1 muscarinic acetylcholine receptors in brain. (1998) (5)
- Synthesis of nor-β-CIT, β-CIT and trimethylstannyl-β-CT (1995) (5)
- Dopamine D2/D3 receptor occupancy of apomorphine evaluated with the agonist radioligand [11C]MNPA and the antagonist radioligand [11C]Raclopride. A PET evaluation in the non-human primate brain (2006) (5)
- NCQ 298, a new selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors (2005) (5)
- β-Amyloid binding in elderly subjects with declining or stable episodic memory function measured with PET and [11C]AZD2184 (2015) (5)
- [11C]raclopride positron emission tomography study of dopamine‐D2/3 receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects (2020) (5)
- Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT. (1998) (5)
- Autoradiographic comparison of [125I]epidepride and [125I]NCQ 298 binding to human brain extrastriated dopamine receptors. (1997) (5)
- Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung — a test-retest PET study in control subjects (2020) (5)
- PET analysis of alcohol interaction with the brain disposition of [11C]flumazenil (2005) (5)
- Kinfitr — an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability (2020) (5)
- AZD4694: Fluorinated Positron Emission Tomography (PET) radioligand for detection of β-amyloid deposits (2009) (5)
- Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [11C]Raclopride in Non-human Primates (2017) (4)
- Dopamine Receptor Occupancy and Plasma Haloperidol Levels-Reply (1989) (4)
- Dose-dependent binding of AZD3783 to brain 5-HT 1B receptors in non-human primates and human subjects: a positron emission tomography study (2011) (4)
- Dr. Talvik and Colleagues Reply (2002) (4)
- [Cerebral uptake and regional distribution of [11C]-vinpocetin after intravenous administration to healthy men: a PET study]. (2002) (4)
- Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process? (2019) (4)
- PET in Neuropsychiatric Drug Development (1995) (4)
- Drug interaction studies with remoxipride (1990) (4)
- Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676 (2016) (4)
- The potential of positron-emission tomography for pharmacokinetic and pharmacodynamic studies of neuroleptics. (1989) (4)
- PET-Determination of Central D1- and D2-Dopamine Receptor Occupancy in Neuroleptic Treated Schizophrenics (1987) (4)
- Scatchard Analysis of the D2 Receptor Agonist [C-11]MNPA in the Monkey Brain Using PET (2005) (3)
- PET evaluation of the partial dopamine D1 receptor agonist radioligands R- and S-[11C]N-Methyl-NNC 01-0259 (2006) (3)
- Synthesis of nor-beta-CIT, beta-CIT and trimethylstannyl-beta-CT. (1995) (3)
- COMT inhibition prevents the formation of lipophilic radiometabolites of catechols, — An example with (S)-[11C]N-methyl-NNC 01-0259 (2008) (3)
- Interaction study between remoxipride and biperiden (2005) (3)
- Potential for imaging the high-affinity state of the 5-HT1B receptor: a comparison of three PET radioligands with differing intrinsic activity (2019) (3)
- Positron emission tomography studies on dopamine receptors in Schizophrenia. Discussion (1995) (3)
- Preparation of a potential positron emission tomographic radioligand for the dopamine transporter (1994) (3)
- RESEARCH ARTICLE Investigation of the Metabolites of (S,S)-( 11 C) MeNER in Humans, Monkeys and Rats (2009) (3)
- New radioligands for pet-examination of central muscarinic receptors (1994) (3)
- TSPO binding may also represent ‘resting’ microglia (2015) (3)
- A PET study of [ 11 C ] β-CIT-FE binding to the dopamine transporter in the monkey and human brain (2000) (2)
- S.26.03 A PET-study of extrastriatal D2-dopamine receptors (1997) (2)
- Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B (2020) (2)
- Dopamine D2/3 receptor occupancy of apomorphine in the non-human primate brain does not support the existence of two affinity states in vivo (2008) (2)
- [11C]AZ10419369: A selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET); Characterization in cynomolgus monkey brain (2008) (2)
- [Cerebral uptake and metabolism of (11C) Vinpocetine in monkeys: PET studies]. (1999) (2)
- Advancement in PET quantification using 3D-OP-OSEM PSF reconstruction with the HRRT (2008) (2)
- Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain (2010) (2)
- Quantitative analyses of [11C]AZ10419369 binding to 5-HT1B receptors in the human brain (2008) (2)
- In response to the letter “[11C]raclopride and extrastriatal binding to D2/3 receptors” (2019) (2)
- Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: 18F-AZD9272 (2020) (2)
- Decreased D1-dopamine receptor binding in drug naive schizophrenic patients examined by pet (1995) (2)
- Radioactive metabolites of the 5-HT1A receptor pet radioligand, [carbonyl-11C]way-100635, measured in human plasma samples (2001) (2)
- Test-retest variability of [C-11]raclopride in rat using PET/MRI (2012) (2)
- Confirmation of fenfluramine effect on 5-HT1B binding of [11C]AZ10419369 using an equilibrium approach (2010) (2)
- Serotonin 5-HT1A receptor binding and self-transcendence in healthy control subjects - a replication study using Bayesian hypothesis testing (2017) (2)
- LIGAND SELECTION FOR PET STUDIES OF D1 DOPAMINE RECEPTORS. RELATIONSHIP BETWEEN DISTRIBUTION OF BINDING SITES AND mRNA FOR DAARPP32 IN THE HUMAN BRAIN (1992) (2)
- Positron Emission Tomography (PET) Studies with Ligands for Cholinergic Receptors in the Human Brain (1995) (2)
- Dopamine and Serotonin Receptor Occupancy in Patients Treated with Antipsychotics (1996) (2)
- Visualization of Neuroreceptor Functions in the Living Human Brain (1989) (2)
- Clozapine and dopamine D2 blockade. Authors' reply (2002) (1)
- D-Amphetamine decreases 5-HT1B receptor binding of [11C]AZ10419369 in the monkey brain (2011) (1)
- [18F]Flumazenil for central benzodiazepine receptor imaging and its comparison with [11C] in human brain (2007) (1)
- Long-time persistence of D2 dopamine receptor occupancy after discontinuation of haloperidol decanoate (1996) (1)
- Comparisons of central benzodiazepine receptor mapping tracers [18F]Flumazenil and [11C]Flumazenil presentation (2006) (1)
- Pharmacokinetic analysis of plasma curves obtained after i.v. injection of the PET radioligand [11C] raclopride provides a likely explanation for rapid radioligand metabolism (2012) (1)
- Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694 (2010) (1)
- Serotonin 5-HT1A receptor binding and self-transcendence in healthy control subjects—a replication study using Bayesian hypothesis testing (2018) (1)
- An HPLC-method for determination of ligand metabolism during PET studies with [11C]metaraminol and [11C]norepinephrine. (1995) (1)
- P-4-61 Autoradiographic comparison of D2- and D3-dopamine receptor localization in the post mortem human brain using [125I]epidepride and [3H]PD 128907 (1995) (1)
- Effect of amphetamine on dopamine D2 receptor binding in the primate brain with the agonist ligand [11C]MNPA (2005) (1)
- Radiosynthesis of [11C]MNPA from the precursor (R)-(−)-2-hydroxy-10,11-acetonide-NPA and a preliminary test–retest PET analysis in monkey brain (2008) (1)
- AZD4694: Fluorinated Positron Emission Tomography (PET) radioligand for detection of β-amyloid deposits (2009) (1)
- Dopamine and cognitive aging: A strong relationship (2007) (1)
- [18F]6FPWAY — a prospective 5-HT1A receptor radioligand — radiolabeling and pet examination in monkey — comparison with [11C]6FPWAY (2001) (1)
- [18F]MCL-524, an 18F-labeled dopamine D2/D3 receptors agonist radioligand with higher binding signal than [11C]MNPA (2012) (1)
- A comparison of amphetamine induced changes in agonist and antagonist radioligand binding potential on the dopamine D2 receptor in primate brain (2005) (1)
- D2- and 5-HT2 receptor occupancy in “mega-dose” treated schizophrenic patients (1996) (1)
- No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis (2021) (1)
- Quantitative analysis of dopamine D2 receptor binding in human brain using PET with an agonist radioligand [11C]MNPA (2008) (1)
- COMT inhibition is a method for avoidance of lipophilic radiometabolites of catechols, exemplified with (S)-[C-11]N-methyl-NNC 01-0259 (2007) (1)
- PET determination of robalzotan occupancy of 5-HT1A receptors in the monkey brain (1998) (1)
- PET Studies in the Early Clinical Development of a New Antipsychotic (1995) (1)
- 145. Translocator protein (TSPO) as a biomarker of microglia activation: PET imaging using [11C]PBR28 in Parkinson’s disease (2013) (1)
- Synthesis of [11C]2β-carbomethoxy-3β-(3′-iodo-4′-methyl, -ethyl and isopropyl phenyl)nortropane as potential radiotracers for examination of the serotonin transporter with positron emission tomography (2000) (1)
- P2.14-33 An Open-Label PET-MRI Study to Determine Brain Exposure of Osimertinib in Patients with EGFR Mutant NSCLC and CNS Metastases (2019) (1)
- A novel principle of radiotracer administration in human brain mapping: pet studies on brain uptake and distribution of orally and intravenously administered [11C]vinpocetine (2001) (1)
- PET studies of D1 and D2 dopamine receptors in drug naive schizophrenic patients (1991) (1)
- Preparation and Examination of Labelled Stereoisomers in Vivo by Pet (1995) (1)
- Synthesis of five benzamide analogs. Comparison with positron emission tomography. (1991) (1)
- PET Examination of Central D2 dopamine and 5‐HT2 Receptor Occupancy by Risperidone (1992) (1)
- Striatai and extrastriatal D2-dopamine receptor occupancy during haloperidol and ciozapine treatment (1998) (1)
- Comparison of beta-amyloid imaging using congo red and thioflavin T derivatives (2012) (1)
- PET AND AUTORADIOGRAPHY OF BENZODIAZEPINE RECEPTOR BINDING WITH RADIOLABELLED FLUMAZENIL AND RO 15‐4513. (1992) (1)
- Synthesis and binding properties of [3H]NNC 12-0781, a new radioligand for the dopamine reuptake system. (1995) (1)
- Current concepts in schizophrenia: international symposia report new standards for assessment and treatment. Part I: Pathophysiology research prompts assessment updates. (1995) (1)
- GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans (2016) (1)
- [Swedish research in frontline. Positron emission tomography shows the brain's receptor functions in psychiatric diseases]. (1984) (1)
- Radiolabeling, preliminary biological evaluation and pet examination in monkey of 5‐methyl‐6‐nitroquipazine — a potential serotonin transporter radioligand (2001) (1)
- Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness (2018) (1)
- Cognitive Performance in Drug-naÏve First Episode Schizophrenia (FES) Patients (2015) (1)
- Neurokinin-3 Receptor Binding in Guinea Pig, Monkey, and Human Brain: In Vitro and in Vivo Imaging Using the Novel Radioligand, [18F]Lu AF10628 (2016) (1)
- Attenuation correction in PET-transmission vs. contour finding in the study of [/sup 11/C]raclopride binding (1993) (1)
- Low convergent validity of FLB 457 (2020) (0)
- Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Pet Study Using [ 11C ] PBR28 and Machine Learning Enhanced Analysis (2021) (0)
- Evaluation of Two Automated Methods for PET Region of Interest Analysis (2014) (0)
- Dr. Nordström and Colleagues Reply (1996) (0)
- Synthesis of 11C-labeled (S,S)-CFMME and (R)-OHDMI and their evaluation as candidate radioligands for imaging norepinephrine transporters with PET (2006) (0)
- PET STUDIES OF ATYPICAL ANTIPSYCHOTICS (2000) (0)
- Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers. (2023) (0)
- Dopamine transporter binding in patients with juvenile myoclonic epilepsy using [11C]PE2I and PET (2010) (0)
- IMAGING DRUG DELIVERY TO THE CNS USING TRANSLATIONAL POSITRON EMISSION TOMOGRAPHY STUDIES (2013) (0)
- The novel mGluR5 radioligand [ 11 C]AZ11696415: Palladium mediated 11 C-cyanation and initial in vivo characterization in the cynomolgus monkey brain using positron emission tomography (PET) (2010) (0)
- Visualizing the central 5-HT1B receptor with PET in rats (2012) (0)
- Dopamine transporter binding using [11C]PE2I and PET corrected for tissue heterogeneity and partial volume effect (2007) (0)
- The dopamine hypothesis of schizophrenia : The role of pet (2004) (0)
- P.2.115 PET examinations or thalamic D2 receptors in schizophrenic patients (2003) (0)
- Development of PET Radioligands for the Quantitation of Serotonin Receptors in the Human Brain (1998) (0)
- S-52-1 Pet-studies on the dopamine system in vivo (1996) (0)
- On the pathophysiology of schizophrenia (2003) (0)
- A radiopharmaceutical agent useful in benzodiazine radioiodinated benzodiazepine derivatives and their use in the diagnosis (1996) (0)
- S.03.02 PET studies on the dopamine system in vivo (1996) (0)
- Distribution of Serotonin Receptor Subtypes in the Post-Mortem Human Brain (1998) (0)
- Extra-striatal dopamine receptors studied with [125I]epideprideIn VITRO and [[11C]FLB 457in vivo (1995) (0)
- GLUTAMATERGIC NEUROTRANSMISSION IN PSYCHIATRIC DISORDERS (2016) (0)
- Synthesis of [(CO)-C-11]Raclopride and a Comparison with [(CH3)-C-11]Raclopride in a Monkey PET Study (2015) (0)
- Evaluation of Errors Using Graphical Techniques (1987) (0)
- P.1.06 Limbic dopamine D2-receptor binding and social desirability (2009) (0)
- Positron emission tomography shows high specific uptake of racemic carbon-11 labelled norepinephrine in the primate heart (2004) (0)
- Effect of amphetamine on dopamine D2 receptors binding in the primate brain with the new agonist ligand [C-11]MNPA (2004) (0)
- Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: A template-based analysis (2014) (0)
- A Voxelwise Analysis of the Relationship between White Matter Integrity and Impulsivity in Men with Schizophrenia (2004) (0)
- [ 18 F]AZD4694 — A new PET radioligand for sensitive detection of β-amyloid deposits (2010) (0)
- PET and antipsychotic drugs — background (2002) (0)
- Decreased 5‐HT1A binding in mild Alzheimer's disease—A positron emission tomography study (2022) (0)
- A new quantitative approach to estimate binding parameters reducing the effect of radiometabolites using three steps of kinetic analysis (2013) (0)
- Editorial Board (2009) (0)
- PET SCANNING OF DOPAMINE RECEPTORS AND PSYCHOSIS (1992) (0)
- P.3.24 Lower 5-HT1A receptor binding in patients with borderline personality disorder: a PET study using [11C]WAY100635 (2008) (0)
- DOPAMINERECEPTORS ANDNEUROLOGICALSIDE EFFECTS (2010) (0)
- P.1.e.021 In vivo assessment of changes in serotonin release in the non-human primate brain using PET and [11C]AZ10419369 (2010) (0)
- PET examination of the monkey heart with high specific radioactivity [11C]norepinephrine and [11C]metaraminol. (1995) (0)
- Changes in cortical D1 receptor binding associated with training-induced changes in working memory capacity. (2009) (0)
- 5-HT1B receptor imaging in Parkinson's disease with 11C-AZ10419369 and positron emission tomography (2012) (0)
- PET in the Development of Dopamine D1 Antagonists as New Potential Antipsychotic Drugs (1995) (0)
- PET imaging of brain neurotransmission (2002) (0)
- The application of positron emission tomography in psychiatry (1988) (0)
- No "ceiling effect" observed with the exogenous dopamine agonist apomorphine - A PET study with the dopamine D-2 receptor agonist radioligand [C-11]MNPA and antagonist radioligand [C-11]Raclopride (2006) (0)
- Detailed mapping of dopamine D2 receptors in the human limbic system using FLB 457 binding analysis in wavelet space (2001) (0)
- Synthesis and Preclinical Evaluation of [11C]AZ11895530 for PET Imaging of the Serotonin 1A Receptor. (2022) (0)
- Image derived input function using a multivariate analysis method based on pair-wise correlation between PET-image voxels (2012) (0)
- TOBACCO SMOKING IN PSYCHIATRIC PATIENTS-A HARMFUL SELF-MEDICATION WITH NICOTINE? (2014) (0)
- Microdosing of radiolabeled CNS drugs in non-human primates. Assessment of brain exposure and dose dependent effects on brain exposure using positron emission tomography (2012) (0)
- Stabilizing the dopamine-serotonin system: a new goal in the management of schizophrenia (2002) (0)
- Two new halogenated analogues of WAY-100635 as potential PET radioligands for the study of 5-HT1A receptors. (2000) (0)
- PET D1-Receptor Studies in Schizophrenia (1996) (0)
- Pet-Studies Using 11C-TZTP Derivatives for the Visualization of Muscarinic Receptors in the Human Brain (1997) (0)
- Regional distribution of high and low affinity states of dopamine D2/3 receptor binding in humans: A PET study using [11C]MNPA and [11C]raclopride (2010) (0)
- M7. LOWER THALAMIC DOPAMINE D2-RECEPTOR BINDING IN DRUG-NAIVE PATIENTS WITH PSYCHOSIS – A REPLICATION STUDY USING POSITRON EMISSION TOMOGRAPHY (2020) (0)
- Effect of fenfluramine on 5-HT1B binding of [11C]AZ10419369 in the primate brain (2009) (0)
- Low effect of amphetamine on the binding of the partial dopamine D-1 receptor agonist radioligand [C-11] N-methyl-NNC 01-0259 (2006) (0)
- Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [11C]MADAM PET study (2015) (0)
- S-18-2 Role of serotonin in psychosis (1995) (0)
- Dr. Borg and Colleagues Reply (2004) (0)
- Brain exposure of osimertinib in patients with EGFRm NSCLC and brain metastases: a PET and MRI study. (2023) (0)
- PL01. 1 The interface between neuroscience and psychiatry (2000) (0)
- P.3.004 Amphetamine-opioid interactions in the human brain reward system – a PET study using [11C]carfentanil (2012) (0)
- Evaluation of two C-methyl derivatives of C-11-WAY-100635 as potential radioligands for 5-HT1A receptors. (2002) (0)
- P.3.02 Molecular imaging of the 5-HT1A receptor and 5-HTT in relation to cognitive functions in man (2008) (0)
- Is the 5-HT2-Receptor a Target for Antipsychotic Drug Action? PET Studies on Dopamine (D2 and Serotonin (5-HT2) Receptor Occupancy in Patients and Healthy Subjects (1995) (0)
- Welcome and introduction (2002) (0)
- Radiofarmaseutika of the preparations were radiojoderade bentsodiatsepinanaloger Science deras anvaendning i diaknostik (1996) (0)
- Amyloid PET imaging using AZD4694 and unusually brief radiotracer uptake and scanning periods (2012) (0)
- O-27-9 Reduced D1-dopamine receptor binding in schizophrenia — Relation to psychopathology (1996) (0)
- Application of cross-species PET imaging to assess neurotransmitter release in brain (2015) (0)
- Amyloid PET imaging using AZD4694 and unusually brief radiotracer uptake and scanning periods (2012) (0)
- Modeling of PET data in CNS drug discovery and development (2013) (0)
- Glia Imaging Shows Clinical Utility in Differentiating Parkinson's Disease from Multiple System Atrophy (2022) (0)
- Effect of ligand mass dose on binding of the β-amyloid specific radioligand [18F]AZD4694 (NAV4694) (2013) (0)
- Decrease of D1-dopamine receptor binding in the frontal cortex of neuroleptic naive schizophrenic patients measured by PET (1996) (0)
- P.1.g.069 Relationship between dose, plasma concentration and GABA-A receptor occupancy by partial GABA-A receptor modulators (2015) (0)
- Molecular Imaging (2020) (0)
- The Central Role of Molecular Imaging in Clinical Neuroscience (2008) (0)
- Dopamine transporter in the nigrostriatal system of adolescents with ADHD and neurocognitive performance (2003) (0)
- The authors reply (1996) (0)
- P.1.i.053 Associations between central chemokine levels and glial activation in first episode psychosis – a positron emission tomography study (2017) (0)
- Abstract # 1847 Cross-sectional and longitudinal associations between immune cells in blood and brain – A TSPO PET study in healthy control subjects (2016) (0)
- D1- and D2-dopamine receptor occupancy during treatment with classical and atypical neurpleptics (1990) (0)
- P.1.e.030 In vivo monoamine transporter occupancy by venlafaxine and milnacipran in non-human primates (2011) (0)
- O-27-5 Autoradiographic localization of 5-HT1A-receptors in the human brain (1996) (0)
- GABA(A) Receptors in Autism - a Multicenter Positron Emission Tomography Study (2015) (0)
- S-45-2 Distribution of dopamine receptor subtypes in the post-mortem human brain (1996) (0)
- Beta-amyloid binding of [3]AZD4694 and [3H]AV45 in vitro (2011) (0)
- Radioiodination of SB 207710 as a prospective radioligand for imaging 5-HT4 receptors in vivo-autoradiography of [125I] SB 207710 against human brain tissue (1999) (0)
- The metabolite pattern of [123I]beta-CIT determined with a gradient HPLC method. (1995) (0)
- Kinetic analysis of receptor binding with positron emission tomography. (1991) (0)
- Automated system for parametric image analysis in neuroreceptor binding studies with PET (2008) (0)
- Neuroimaging in Psychiatric Drug Development and Radioligand Development for New Targets (2020) (0)
- The dopamine hypothesis of schizophrenia (2004) (0)
- Common brain disorders are associated with heritable patterns of apparent aging of the brain (2019) (0)
- European Association of Nuclear Medicine Congress 26–30 August 1995, Brussels, Belgium (2004) (0)
- (18)F6FPWAY-synthesis and initial investigation as a prospective 5-HT1A receptor radioligand in vivo. (2001) (0)
- Quantitative analysis of F-FE-PE2I binding to the dopamine transporter in Parkinson’s disease (2015) (0)
- Dopamine transporter binding corrected for tissue heterogeneity and partial volume effect using [11C]PE2I and PET (2006) (0)
- Proof of lung muscarinic receptor occupancy by tiotropium: Translational Positron Emission Tomography studies in non-human primates and humans (2023) (0)
- D2 and 5-HT2 receptor occupancy in antipsychotic drug treated patients (1994) (0)
- The Future of Psychopharmacology and Positron Emission Tomography (1990) (0)
- Amyloid PET imaging using AZD4694 and unusually brief radiotracer uptake and scanning periods (2012) (0)
- Increasing the accuracy of in vivo quantification of dopamine-D2/D3 receptor binding in the human brain by partial volume effect correction (2006) (0)
- [C]PBB3 binding in Aβ(-) or Aβ(+) Corticobasal syndrome. (2023) (0)
- PET Studies of Patients Treated with Antipsychotic Drugs (1989) (0)
- D2-density, personality traits, and negative symptoms of schizophrenia (1998) (0)
- PET evaluation of the dopamine D2 receptor agonist (2004) (0)
- Optimal acquisition time window for quantification of dopamine transporter availability with [18F]FE-PE2I in controls and PD patients (2015) (0)
- Useful in the radiopharmaceutical in the radioiodinated benzodiazepine derivatives and their use in the diagnosis (1996) (0)
- A new quantitative approach for dopamine transporter binding using [11C]PE2I and PET allowing BBB-penetrating radiolabeled metabolite (2011) (0)
- P-13-2 In vivo examination of the Pre- and postsynaptic dopamine neurons in huntington's disease (1996) (0)
- P.1.j.040 Social cognition in autism spectrum disorder is associated with brain serotonin transporter availability (2017) (0)
- SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study (2012) (0)
- The characteristics of the relationships between D2 receptor occupancy, antipsychotic effect and plasma prolactin (1999) (0)
- 11 Early clinical development of amyloid-beta specific PET radioligand [18F]AZD4694 (2012) (0)
- [I-123]SB 207710 exhibits 5-HT4 receptor-selective binding in monkey brain in vivo. (2000) (0)
- Dopamine Receptors and Neurological Side Effects (1996) (0)
- 16-4 PET studies of serotonergic mechanisms in the treatment of schizophrenia (1997) (0)
- Glutamate 5 receptor availability differences in twins discordant for autism and controls, do shared genetics matter (2023) (0)
- S.06.03 Is dopamine a variable in PET-studies on drug induced receptor occupancy? (2003) (0)
- Two new C-methyl analogues of WAY-100635-preparation, labeling with carbon-11 and evaluation as PET radioligands for brain 5-HT1A receptors in monkey (2002) (0)
- Abstract 2641: AZD4635 A2Areceptor occupancy in cynomolgus monkey using PET and its application to an oncology clinical development program (2017) (0)
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What Schools Are Affiliated With Lars Farde?
Lars Farde is affiliated with the following schools: