Lars Siegfried Maier
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Lars Siegfried Maierbiology Degrees
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Developmental Biology
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Molecular Biology
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Biology
Lars Siegfried Maier's Degrees
- PhD Molecular Biology University of California, Berkeley
Why Is Lars Siegfried Maier Influential?
(Suggest an Edit or Addition)Lars Siegfried Maier's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pluripotency of spermatogonial stem cells from adult mouse testis (2006) (888)
- PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock (2017) (614)
- Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells (2008) (500)
- Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. (2006) (499)
- Generation of induced pluripotent stem cells from human cord blood. (2009) (485)
- The &dgr;C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure (2003) (479)
- Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium. (1999) (470)
- Transgenic CaMKII&dgr;C Overexpression Uniquely Alters Cardiac Myocyte Ca2+ Handling: Reduced SR Ca2+ Load and Activated SR Ca2+ Release (2003) (444)
- Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium. (1999) (408)
- Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial (2017) (405)
- The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload (2009) (403)
- CaMKII-Dependent Diastolic SR Ca2+ Leak and Elevated Diastolic Ca2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation (2010) (346)
- Rate Dependence of [Na+]i and Contractility in Nonfailing and Failing Human Myocardium (2002) (322)
- Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart. (2007) (316)
- Influence of the novel inotropic agent levosimendan on isometric tension and calcium cycling in failing human myocardium. (1998) (314)
- Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond. (2002) (307)
- Differential Cardiac Remodeling in Preload Versus Afterload (2010) (276)
- Reactive Oxygen Species–Activated Ca/Calmodulin Kinase II&dgr; Is Required for Late INa Augmentation Leading to Cellular Na and Ca Overload (2011) (271)
- Blocking Late Sodium Current Reduces Hydrogen Peroxide-Induced Arrhythmogenic Activity and Contractile Dysfunction (2006) (269)
- Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation. (2008) (268)
- Altered Na(+) currents in atrial fibrillation effects of ranolazine on arrhythmias and contractility in human atrial myocardium. (2010) (251)
- One‐Year Outcomes after PCI Strategies in Cardiogenic Shock (2018) (249)
- Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial (2018) (239)
- Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation (2013) (239)
- Inhibition of Elevated Ca2+/Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium (2010) (227)
- Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. (2013) (215)
- CaMKIIδ Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses* (2007) (211)
- Increased Sarcoplasmic Reticulum Calcium Leak but Unaltered Contractility by Acute CaMKII Overexpression in Isolated Rabbit Cardiac Myocytes (2006) (204)
- Functional effects of endothelin and regulation of endothelin receptors in isolated human nonfailing and failing myocardium. (1999) (186)
- Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro. (2013) (177)
- Calcium/Calmodulin-Dependent Protein Kinase II Contributes to Cardiac Arrhythmogenesis in Heart Failure (2009) (173)
- Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation (2013) (173)
- Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. (2002) (171)
- RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study. (2013) (170)
- Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts. (2013) (158)
- Redox regulation of sodium and calcium handling. (2013) (139)
- Generation of Functional Cardiomyocytes From Adult Mouse Spermatogonial Stem Cells (2007) (136)
- Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca2+ Leak in Human Cardiac Pathology (2013) (129)
- Differences in Ca(2+)-handling and sarcoplasmic reticulum Ca(2+)-content in isolated rat and rabbit myocardium. (2000) (124)
- Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation. (2020) (123)
- Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents (2009) (123)
- Targets for therapy in sarcomeric cardiomyopathies. (2015) (121)
- Cardiac CaM Kinase II Genes &dgr; and &ggr; Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy (2014) (119)
- Cardiac fibroblasts support cardiac inflammation in heart failure (2014) (118)
- Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. (2013) (116)
- In vivo model with targeted cAMP biosensor reveals changes in receptor–microdomain communication in cardiac disease (2015) (114)
- Empagliflozin reduces Ca/calmodulin‐dependent kinase II activity in isolated ventricular cardiomyocytes (2018) (112)
- Abnormalities of calcium metabolism and myocardial contractility depression in the failing heart (2009) (108)
- CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes. (2011) (107)
- A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy (2010) (107)
- Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials. (2007) (104)
- Unfavourable consequences of chronic cardiac HIF-1α stabilization. (2012) (102)
- Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis. (2015) (100)
- Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδC can be reversed by inhibition of late Na+ current (2010) (100)
- Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death. (2015) (98)
- Influence of mild hypothermia on myocardial contractility and circulatory function (2001) (96)
- Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation. (2010) (95)
- Role of ranolazine in angina, heart failure, arrhythmias, and diabetes. (2012) (95)
- Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes. (2013) (92)
- Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. (2010) (91)
- Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease. (2013) (91)
- The Cardiac CaMKII Genes δ and γ Contribute Redundantly to Adverse Remodeling but Inhibit Calcineurin-Induced Myocardial Hypertrophy (2014) (90)
- Influence of Pyruvate on Contractile Performance and Ca2+ Cycling in Isolated Failing Human Myocardium (2002) (90)
- Effects of mild hypothermia on hemodynamics in cardiac arrest survivors and isolated failing human myocardium (2010) (87)
- Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart (2011) (84)
- Stretch-dependent slow force response in isolated rabbit myocardium is Na+ dependent. (2003) (83)
- Myocyte Nitric Oxide Synthase 2 Contributes to Blunted β-Adrenergic Response in Failing Human Hearts by Decreasing Ca2+ Transients (2004) (81)
- A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway (2017) (79)
- Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy: The RESTYLE-HCM Randomized, Double-Blind, Placebo-Controlled Study (2018) (78)
- Mechanism of action of the new anti-ischemia drug ranolazine (2007) (77)
- Ranolazine in the treatment of atrial fibrillation: Results of the dose-ranging RAFFAELLO (Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion) study. (2015) (75)
- Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility. (2007) (69)
- Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology. (2014) (69)
- Endothelin-1 enhances nuclear Ca2+ transients in atrial myocytes through Ins(1,4,5)P3-dependent Ca2+ release from perinuclear Ca2+ stores (2008) (66)
- CaMKII as a target for arrhythmia suppression. (2017) (65)
- Negative Inotropy of the Gastric Proton Pump Inhibitor Pantoprazole in Myocardium From Humans and Rabbits: Evaluation of Mechanisms (2007) (63)
- A Novel Mechanism for the Treatment of Angina, Arrhythmias, and Diastolic Dysfunction: Inhibition of Late INa Using Ranolazine (2009) (61)
- Mild metabolic acidosis impairs the β-adrenergic response in isolated human failing myocardium (2012) (60)
- Relevance of Brain Natriuretic Peptide in Preload-Dependent Regulation of Cardiac Sarcoplasmic Reticulum Ca2+ ATPase Expression (2006) (58)
- Heart failure with preserved ejection fraction: current management and future strategies (2017) (58)
- Na+ channel function, regulation, structure, trafficking and sequestration (2015) (57)
- Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII (2015) (57)
- Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator. (2015) (56)
- Ranolazine for the Treatment of Heart Failure With Preserved Ejection Fraction: Background, Aims, and Design of the RALI‐DHF Study (2011) (54)
- Na(+)-Ca(2+) exchanger overexpression predisposes to reactive oxygen species-induced injury. (2003) (53)
- Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes. (2004) (53)
- Extracorporeal life support in patients with acute myocardial infarction complicated by cardiogenic shock - Design and rationale of the ECLS-SHOCK trial. (2021) (52)
- Cardiac RKIP induces a beneficial β-adrenoceptor–dependent positive inotropy (2015) (52)
- Frequency-dependent changes in contribution of SR Ca2+ to Ca2+ transients in failing human myocardium assessed with ryanodine. (1998) (51)
- Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium. (1998) (51)
- NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII. (2014) (50)
- Ca(2+) handling in isolated human atrial myocardium. (2000) (50)
- Sarcoplasmic reticulum Ca2+ load in human heart failure (2002) (50)
- Effects of large volume, ice-cold intravenous fluid infusion on respiratory function in cardiac arrest survivors. (2009) (49)
- Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. (2006) (49)
- Role of CaMKII for signaling and regulation in the heart. (2009) (49)
- Empagliflozin inhibits Na+/H+ exchanger activity in human atrial cardiomyocytes (2020) (48)
- Generation of Highly Purified Human Cardiomyocytes from Peripheral Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cells (2015) (48)
- Transgenic CaMKII C Overexpression Uniquely Alters Cardiac Myocyte Ca (2003) (48)
- Influence of stimulation frequency on [Na+]i and contractile function in Langendorff-perfused rat heart. (1997) (47)
- Mitogen-Activated Protein Kinase-Activated Protein Kinases 2 and 3 Regulate SERCA2a Expression and Fiber Type Composition To Modulate Skeletal Muscle and Cardiomyocyte Function (2013) (47)
- Conditional Neuronal Nitric Oxide Synthase Overexpression Impairs Myocardial Contractility (2007) (46)
- Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor. (2018) (46)
- Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. (2014) (46)
- Antiarrhythmic effects of dantrolene in human diseased cardiomyocytes. (2017) (45)
- Ca2+/calmodulin‐dependent protein kinase II equally induces sarcoplasmic reticulum Ca2+ leak in human ischaemic and dilated cardiomyopathy (2014) (45)
- Influence of cyclosporine A on contractile function, calcium handling, and energetics in isolated human and rabbit myocardium. (2000) (44)
- Leptin promotes the mobilization of vascular progenitor cells and neovascularization by NOX2-mediated activation of MMP9. (2012) (43)
- Prediction of mortality benefit based on periodic repolarisation dynamics in patients undergoing prophylactic implantation of a defibrillator: a prospective, controlled, multicentre cohort study (2019) (42)
- Rationale and design of the DIGIT‐HF trial (DIGitoxin to Improve ouTcomes in patients with advanced chronic Heart Failure): a randomized, double‐blind, placebo‐controlled study (2019) (42)
- Reduction in treatment times through formalized data feedback: results from a prospective multicenter study of ST-segment elevation myocardial infarction. (2012) (42)
- Hotline update of clinical trials and registries presented at the German Cardiac Society meeting 2008 (2008) (41)
- Pre- and early in-hospital procedures in patients with acute coronary syndromes: first results of the “German chest pain unit registry” (2012) (41)
- Panel of emerging cardiac biomarkers contributes for prognosis rather than diagnosis in chronic heart failure. (2014) (41)
- Coexistence and outcome of coronary artery disease in Takotsubo syndrome. (2020) (40)
- Gingerol, isoproterenol and ouabain normalize impaired post-rest behavior but not force-frequency relation in failing human myocardium. (2000) (40)
- Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner. (2014) (39)
- Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction. (2014) (39)
- CaMKII regulation of cardiac K channels (2014) (38)
- Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality. (2011) (37)
- Novel aspects of excitation–contraction coupling in heart failure (2013) (37)
- Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure (2017) (37)
- Calmodulin and Ca2+/calmodulin kinases in the heart - physiology and pathophysiology. (2007) (37)
- Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy. (2016) (37)
- Regulation of mitochondrial [NADH] by cytosolic [Ca2+] and work in trabeculae from hypertrophic and normal rat hearts. (1998) (36)
- The late Na current as a therapeutic target: where are we? (2013) (36)
- Targeted disruption of Hspa4 gene leads to cardiac hypertrophy and fibrosis. (2012) (36)
- Hemopexin counteracts systolic dysfunction induced by heme‐driven oxidative stress (2017) (36)
- Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII (2013) (35)
- Hotline Update of Clinical Trials and Registries presented at the German Cardiac Society Meeting 2007 (2007) (35)
- CaMKIIdelta overexpression in hypertrophy and heart failure: cellular consequences for excitation-contraction coupling. (2005) (34)
- The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity. (2018) (33)
- Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats. (2005) (32)
- Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart (2018) (32)
- Age-Related Variations in Takotsubo Syndrome. (2020) (31)
- Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart (2018) (30)
- Dysferlin mediates membrane tubulation and links T-tubule biogenesis to muscular dystrophy (2017) (30)
- Enhanced CaMKII-Dependent Late INa Induces Atrial Proarrhythmic Activity in Patients With Sleep-Disordered Breathing (2020) (30)
- Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation (2017) (29)
- The ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisis (2012) (29)
- Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure. (2017) (28)
- Single Institution Experience With Transcatheter Valve-in-Valve Implantation Emphasizing Strategies for Coronary Protection. (2015) (28)
- Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice (2020) (27)
- Disease distribution and outcome in troponin-positive patients with or without revascularization in a chest pain unit: results of the German CPU-Registry (2013) (27)
- The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies? (2013) (27)
- Argatroban versus heparin in patients without heparin-induced thrombocytopenia during venovenous extracorporeal membrane oxygenation: a propensity-score matched study (2021) (27)
- Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. (2014) (26)
- Modulation of Cardiac Na+ and Ca2+ Currents by CaM and CaMKII (2006) (25)
- Remodeling of excitation-contraction coupling in the heart: Inhibition of sarcoplasmic reticulum Ca2+ leak as a novel therapeutic approach (2007) (25)
- Oxidized-CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms. (2020) (25)
- NT-proBNP Predicts Cardiovascular Death in the General Population Independent of Left Ventricular Mass and Function: Insights from a Large Population-Based Study with Long-Term Follow-Up (2016) (24)
- High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts (2006) (24)
- Adaptive servo-ventilation therapy of central sleep apnoea and its effect on sleep quality (2016) (24)
- ECMO in COVID-19—prolonged therapy needed? A retrospective analysis of outcome and prognostic factors (2021) (23)
- Guideline-adherence and perspectives in the acute management of unstable angina - Initial results from the German chest pain unit registry. (2015) (23)
- CaMKII regulation of voltage-gated sodium channels and cell excitability. (2011) (23)
- C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation (2017) (22)
- Reduction of SR Ca2+ leak and arrhythmogenic cellular correlates by SMP-114, a novel CaMKII inhibitor with oral bioavailability (2017) (22)
- Sex-dependent alterations of Ca2+ cycling in human cardiac hypertrophy and heart failure. (2016) (22)
- Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in the heart. (2012) (22)
- Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure (2018) (22)
- While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice. (2013) (21)
- SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure. (2018) (20)
- First clinical evaluation of a novel capacitive ECG system in patients with acute myocardial infarction (2011) (20)
- Mechanisms of cardiac ethanol toxicity and novel treatment options. (2019) (20)
- RNA-expression of adrenomedullin is increased in patients with severe COVID-19 (2020) (20)
- The functional consequences of sodium channel NaV1.8 in human left ventricular hypertrophy (2018) (20)
- Postoperative complications after elective coronary artery bypass grafting surgery in patients with sleep-disordered breathing (2018) (19)
- Self-referral to chest pain units: results of the German CPU-registry (2012) (19)
- Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium. (1998) (19)
- Impaired Ca2+-handling in HIF-1α+/− mice as a consequence of pressure overload (2009) (19)
- Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation (2020) (19)
- Effects on recovery during acidosis in cardiac myocytes overexpressing CaMKII. (2007) (18)
- Invasive treatment of NSTEMI patients in German Chest Pain Units - Evidence for a treatment paradox. (2018) (18)
- Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy (2020) (18)
- The German CPU Registry: comparison of troponin positive to troponin negative patients. (2013) (18)
- New Treatment Options for Late Na Current, Arrhythmias, and Diastolic Dysfunction (2012) (18)
- Whom are we treating with adaptive servo-ventilation? A clinical post hoc analysis (2017) (18)
- Celecoxib modulates hypertrophic signalling and prevents load‐induced cardiac dysfunction (2008) (18)
- Effects of different proton pump inhibitors on cardiac contractility in isolated human failing myocardium. (2011) (17)
- Prevalence of Sleep-Disordered Breathing-Related Symptoms in Patients with Chronic Heart Failure and Reduced Ejection Fraction. (2015) (16)
- The German CPU Registry: Dyspnea independently predicts negative short-term outcome in patients admitted to German Chest Pain Units. (2015) (16)
- Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction (2016) (16)
- The Role of SR Ca2+-Content in Blunted Inotropic Responsiveness of Failing Human Myocardium (2002) (16)
- The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology. (2016) (16)
- Adaptive servo-ventilation and sleep quality in treatment emergent central sleep apnea and central sleep apnea in patients with heart disease and preserved ejection fraction (2018) (16)
- Enhanced Ca2+ influx through cardiac L-type Ca2+ channels maintains the systolic Ca2+ transient in early cardiac atrophy induced by mechanical unloading (2013) (16)
- Limitations of FKBP12.6-directed treatment strategies for maladaptive cardiac remodeling and heart failure. (2011) (16)
- Late sodium current inhibition: the most promising antiarrhythmic principle in the near future? (2014) (15)
- CaMKII and GLUT1 in heart failure and the role of gliflozins. (2020) (15)
- Association of sleep-disordered breathing and disturbed cardiac repolarization in patients with ST-segment elevation myocardial infarction. (2017) (15)
- Relation Between Obesity, Metabolic Syndrome, Successful Long-Term Weight Reduction, and Right Ventricular Function. (2016) (15)
- 3D vena contracta area after MitraClip© procedure: precise quantification of residual mitral regurgitation and identification of prognostic information (2018) (14)
- CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect (2020) (14)
- Admission heart rate in relation to presentation and prognosis in patients with acute myocardial infarction (2016) (14)
- Coronary Artery Ectasia Are Frequently Observed in Patients With Bicuspid Aortic Valves With and Without Dilatation of the Ascending Aorta (2016) (14)
- Prediction of short‐ and long‐term mortality in takotsubo syndrome: the InterTAK Prognostic Score (2019) (14)
- Role of [Na+]i and the emerging involvement of the late sodium current in the pathophysiology of cardiovascular disease (2006) (14)
- CaMKII-mediated increased lusitropic responses to beta-adrenoreceptor stimulation in ANP-receptor deficient mice. (2007) (14)
- Insights into permanent pacemaker implantation following TAVR in a real-world cohort (2018) (14)
- Hotline update of clinical trials and registries presented at the German Cardiac Society Meeting 2009 (2009) (14)
- Exercise training reverses myocardial dysfunction induced by CaMKIIδC overexpression by restoring Ca2+ homeostasis. (2016) (13)
- Dantrolene reduces CaMKIIδC-mediated atrial arrhythmias. (2020) (13)
- Toward a Long-Term Artificial Lung (2020) (13)
- Combined Inhibition of the Renin-Angiotensin System and Neprilysin Positively Influences Complex Mitochondrial Adaptations in Progressive Experimental Heart Failure (2017) (13)
- Guideline-adherence regarding critical time intervals in the German Chest Pain Unit registry (2020) (13)
- Angiotensin‐converting enzyme inhibitor/angiotensin II receptor blocker treatment and haemodynamic factors are associated with increased cardiac mRNA expression of angiotensin‐converting enzyme 2 in patients with cardiovascular disease (2020) (13)
- Kidney injury molecule-1: potential biomarker of acute kidney injury and disease severity in patients with COVID-19 (2021) (12)
- Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4 (2017) (12)
- RANOLAZINE FOR THE TREATMENT OF DIASTOLIC HEART FAILURE IN PATIENTS WITH PRESERVED EJECTION FRACTION: RESULTS FROM THE RALI-DHF STUDY (2012) (12)
- Patients with acute myocarditis and preserved systolic left ventricular function: comparison of global and regional longitudinal strain imaging by echocardiography with quantification of late gadolinium enhancement by CMR (2021) (12)
- Cooperation Between Hypoxia-Inducible Factor 1α and Activating Transcription Factor 4 in Sleep Apnea-Mediated Myocardial Injury. (2020) (12)
- Empagliflozin enhances human and murine cardiomyocyte glucose uptake by increased expression of GLUT1 (2019) (12)
- Method-related effects of adenovirus-mediated LacZ and SERCA1 gene transfer on contractile behavior of cultured failing human cardiomyocytes. (2005) (12)
- Prognostic significance of emergency department bypass in stable and unstable patients with ST-segment elevation myocardial infarction (2018) (12)
- Targeting altered calcium physiology in the heart: translational approaches to excitation, contraction, and transcription. (2007) (12)
- Effects of Ranolazine on Torsades de Pointes Tachycardias in a Healthy Isolated Rabbit Heart Model (2014) (12)
- Predictors of delirium after cardiac surgery in patients with sleep disordered breathing (2019) (12)
- Visualization of transcoronary ablation of septal hypertrophy in patients with hypertrophic obstructive cardiomyopathy: a comparison between cardiac MRI, invasive measurements and echocardiography (2010) (11)
- Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity (2017) (11)
- The role of SR Ca(2+)-content in blunted inotropic responsiveness of failing human myocardium. (2002) (11)
- Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry (2021) (11)
- The adipo‐fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients (2019) (11)
- Secondary hemophagocytic lymphohistiocytosis and severe liver injury induced by hepatic SARS-CoV-2 infection unmasking Wilson’s disease: Balancing immunosuppression (2021) (11)
- Obstructive sleep apnoea but not central sleep apnoea is associated with left ventricular remodelling after acute myocardial infarction (2020) (11)
- Abnormal P‐wave terminal force in lead V1 is a marker for atrial electrical dysfunction but not structural remodelling (2021) (11)
- Calmodulin and Ca 2+ /calmodulin kinases in the heart — Physiology and pathophysiology (2007) (11)
- The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure (2020) (11)
- Characterization and referral patterns of ST-elevation myocardial infarction patients admitted to chest pain units rather than directly to catherization laboratories. Data from the German Chest Pain Unit Registry. (2017) (10)
- Ca2+/calmodulin-dependent protein kinase II is essential in hyperacute pressure overload. (2019) (10)
- Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart. (2020) (10)
- Glucocorticoid stimulation increases cardiac contractility by SGK1-dependent SOCE-activation in rat cardiac myocytes (2019) (10)
- Multislice computed tomography-based prediction of the implantation plane in transcatheter aortic valve implantation: determination of the line of perpendicularity and the implanter's views. (2015) (9)
- Long-term effects of a standardized feedback-driven quality improvement program for timely reperfusion therapy in regional STEMI care networks. (2020) (9)
- Percutaneous Coronary Intervention in Stable Coronary Heart Disease -Is Less More? (2020) (9)
- Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes (2020) (9)
- Bail-Out Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy in a Patient With Takotsubo Cardiomyopathy-Induced Cardiogenic Shock. (2019) (9)
- Data demonstrating the anti-oxidant role of hemopexin in the heart (2017) (9)
- Loss of CASK Accelerates Heart Failure Development (2021) (9)
- Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID‐19 (2020) (9)
- Acute Renal Graft-Versus-Host Disease in a Murine Model of Allogeneic Bone Marrow Transplantation (2017) (8)
- Central sleep apnea predicts pulmonary complications after cardiac surgery. (2020) (8)
- Impact of Body Mass Index on Outcomes in the Edoxaban Versus Warfarin Therapy Groups in Patients Underwent Cardioversion of Atrial Fibrillation (from ENSURE-AF). (2019) (8)
- Vascular Alterations in a Murine Model of Acute Graft-Versus-Host Disease Are Associated With Decreased Serum Levels of Adiponectin and an Increased Activity and Vascular Expression of Indoleamine 2,3-Dioxygenase. (2016) (8)
- P6168Digitoxin serum concentrations affecting patient safety and potential outcome in patients with HFrEF - analyses of the ongoing DIGIT-HF-trial (2017) (8)
- CaMKII δ overexpression in hypertrophy and heart failure : cellular consequences for excitation-contraction coupling (2005) (8)
- A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction (2020) (7)
- Sleep-disordered breathing is independently associated with reduced atrial connexin 43 expression. (2021) (7)
- induced arrhythmogenic activity and contractile dysfunction (2006) (7)
- Mapping genetic changes in the cAMP-signaling cascade in human atria. (2021) (7)
- Resolution of ST deviation after myocardial infarction in patients with and without sleep-disordered breathing (2018) (7)
- Design of the SILICOFCM study: Effect of sacubitril/valsartan vs lifestyle intervention on functional capacity in patients with hypertrophic cardiomyopathy (2020) (7)
- Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor–dependent positive inotropy (2016) (7)
- Sleep-disordered breathing is associated with disturbed cardiac repolarization in patients with a coronary artery bypass graft surgery. (2018) (7)
- Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure (2021) (6)
- Cardiac iron overload promotes cardiac injury in patients with severe COVID-19 (2021) (6)
- Hotline sessions presented at the American College of Cardiology Congress 2009 (2009) (6)
- Diagnostic value of FDG PET/CT imaging in patients with surgically managed infective endocarditis: results of a retrospective analysis at a tertiary center (2020) (6)
- Contribution of the neuronal sodium channel NaV1.8 to sodium- and calcium-dependent cellular proarrhythmia. (2020) (6)
- Inhibition of PI3K improves contractility in alpha1-adrenergically stimulated myocardium. (2008) (6)
- Cardiac Fibrosis Is a Risk Factor for Severe COVID-19 (2021) (6)
- Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry (2021) (6)
- Distinct regulatory effects of myeloid cell and endothelial cell Nox2 on blood pressure (2017) (5)
- Evaluation of a novel portable capacitive ECG system in the clinical practice for a fast and simple ECG assessment in patients presenting with chest pain: FIDET (Fast Infarction Diagnosis ECG Trial) (2012) (5)
- Large emboli on their way through the heart - first live demonstration of large paradoxical embolisms through a patent foramen ovale. (2007) (5)
- Rationale and design of the CONSIDER AF study (2019) (5)
- Cardiac unloading by LVAD support differentially influences components of the cGMP–PKG signaling pathway in ischemic and dilated cardiomyopathy (2018) (5)
- Toward a Long-Term Artificial Lung. (2020) (5)
- Alterations of the renin angiotensin system in human end-stage heart failure before and after mechanical cardiac unloading by LVAD support (2020) (5)
- Frequency-dependence of the slow force response. (2008) (5)
- Diabetes increases mortality after myocardial infarction by oxidizingCaMKII (2013) (5)
- The role of the tubular biomarkers NAG, kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in patients with chest pain before contrast media exposition. (2019) (5)
- Prevalence of Obstructive Coronary Artery Disease in Ambulatory Patients with Stable Angina Pectoris (2015) (5)
- The detrimental potential of arrhythmia‐induced cardiomyopathy (2018) (4)
- Predictors of functional improvement in the short term after MitraClip implantation in patients with secondary mitral regurgitation (2020) (4)
- Erratum to: Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation (2017) (4)
- Ranolazine for atrial fibrillation: buy one get three beneficial mechanisms! (2012) (4)
- Female Patients With Sleep-Disordered Breathing Display More Frequently Heart Failure With Preserved Ejection Fraction (2021) (4)
- Incidence of early intra-cranial bleeding and ischaemia in adult veno-arterial extracorporeal membrane oxygenation and extracorporeal cardiopulmonary resuscitation patients: a retrospective analysis of risk factors (2020) (4)
- The Effect of Gender and Sex Hormones on Cardiovascular Disease, Heart Failure, Diabetes, and Atrial Fibrillation in Sleep Apnea (2021) (4)
- Long-term effects of a standardized feedback-driven quality improvement program for timely reperfusion therapy in regional STEMI care networks. (2020) (4)
- Proteome changes in CaMKIIδC-overexpressing cardiac myocytes. (2010) (4)
- Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models (2021) (4)
- Small conductance Ca-activated K channel: small but powerful proarrhythmogenic? (2013) (4)
- Outcomes Associated with Respiratory Failure for Patients with Cardiogenic Shock and Acute Myocardial Infarction: A Substudy of the CULPRIT-SHOCK Trial (2020) (4)
- Abstract 422: Ca/calmodulin Kinase II Differentially Modulates Transient Outward Potassium Current in Heart Failure (2006) (4)
- The impact of epicardial adipose tissue in patients with acute myocardial infarction (2021) (4)
- Reduced store‐operated Ca2+ entry impairs mesenteric artery function in response to high external glucose in type 2 diabetic ZDF rats (2020) (4)
- [Pathophysiology of chronic myocardial ischemia]. (2013) (4)
- The German CPU registry: Comparison of smokers and nonsmokers (2018) (3)
- SAR296968, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Ca2+ Handling and Contractile Function in Human Atrial Cardiomyocytes (2022) (3)
- Improvement in Risk Stratification in Transcatheter Aortic Valve Implantation Using a Combination of the Tumor Marker CA125 and the Logistic EuroSCORE. (2017) (3)
- Association of Culprit Lesion Location With Outcomes of Culprit-Lesion-Only vs Immediate Multivessel Percutaneous Coronary Intervention in Cardiogenic Shock: A Post Hoc Analysis of a Randomized Clinical Trial. (2020) (3)
- Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation reveals multisite regulation of surface expression and gating (2020) (3)
- The role of diabetes in cardiomyopathies of different etiologies—Characteristics and 1-year follow-up results of the EVITA-HF registry (2020) (3)
- [Heart failure. Excitation-contraction coupling and novel therapeutic options]. (2011) (3)
- Successful weight loss reduces endothelial activation in individuals with severe obesity participating in a multimodal weight loss program. (2021) (3)
- Clinical care for patients with recurrent myocardial ischemia in Germany-the VOICES trial. (2018) (3)
- Empagliflozin Inhibits Cardiac Late Sodium Current by Ca/Calmodulin-Dependent Kinase II (2022) (3)
- Experimental antiarrhythmic targets: CaMKII inhibition - ready for clinical evaluation? (2014) (3)
- Design and rationale for the “Me & My Heart” (eMocial) study: A randomized evaluation of a new smartphone‐based support tool to increase therapy adherence of patients with acute coronary syndrome (2019) (3)
- SCN10A-Dependent Late INa Current: Never Too Late for Cardiac Conduction? (2018) (3)
- Drug Coated Balloon Is Less Effective for Treatment of DES In-Stent Restenosis Both in Native Coronary Arteries and Saphenous Vein Grafts: Results From a Bicenter Registry. (2016) (3)
- Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites (2021) (3)
- Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry (2021) (3)
- Novel Implantable Cardioverter Defibrillator Programming With High Rate Cut-Off, Long Detection Intervals and Multiple Anti-Tachycardia Pacing Reduces Mortality. (2021) (2)
- Effects of visualization of successful revascularization on chest pain and quality of life in chronic coronary syndrome: study protocol for the multi-center, randomized, controlled PLA-pCi-EBO-pilot-trial (2020) (2)
- Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition (2019) (2)
- Vascular Alterations in a Murine Model of Acute Graft-Versus-Host Disease Are Associated with Decreased Serum Levels of Adiponectin and an Increased Activity and Vascular Expression of Indoleamine 2,3-Dioxygenase. (2016) (2)
- St slow force response in isolated rabbit myocardium (2003) (2)
- N‐acetyl‐b‐D‐glucosaminidase: A potential cardiorenal biomarker with a relevant impact on ICD shock therapies and mortality (2020) (2)
- Atrial Fibrillation Burden Specifically Determines Human Ventricular Cellular Remodeling. (2022) (2)
- EXPRESSION OF LYSYL OXIDASE-LIKE 2 (LOXL2) CORRELATES WITH LEFT ATRIAL SIZE AND FIBROTIC GENE EXPRESSION IN HUMAN ATRIAL FIBRILLATION (2014) (2)
- Dysferlin links excitation-contraction coupling to structure and maintenance of the cardiac transverse-axial tubule system. (2020) (2)
- Obstructive sleep apnoea is associated with the development of diastolic dysfunction after myocardial infarction with preserved ejection fraction. (2022) (2)
- Voltage Sensitive Protein 2.3: A Novel Tool to Study Sarcolemmal Structure and Electrical Activity in Mouse Hearts (2011) (2)
- The positive inotropic effect of endothelin-1 is calcium-dependent but not pH-dependent in rabbit papillary muscle: A-01 (2001) (2)
- Whom are we treating with adaptive servo-ventilation? - a clinical post-hoc analysis (2017) (2)
- Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice (2021) (2)
- Achieving Guideline-Directed Heart Rate ControlEarly Posthospitalization. (2019) (2)
- Transients 2 + Human Hearts by Decreasing Ca-Adrenergic Response in Failing β Myocyte Nitric Oxide Synthase 2 Contributes to Blunted (2004) (1)
- Evaluation of a multimarker panel in chronic heart failure: a 10-year follow-up. (2021) (1)
- P334Identification of suitable reference genes for gene expression studies in normal and pathological human heart tissues (2014) (1)
- P1509Empagliflozin directly improves diastolic function in human heart failure (2018) (1)
- Effects of ON-Hours Versus OFF-Hours Admission on Outcome in Patients With Myocardial Infarction and Cardiogenic Shock (2020) (1)
- Acute renal graft-versus-host disease in a murine model of allogeneic bone marrow transplantation. (2017) (1)
- 080CaMKII oxidation causes increased atrial fibrillation in diabetic mice (2017) (1)
- The Role of Local Ca2+ Release for Ca2+ Alternans and SR-Ca2+ Leak (2017) (1)
- [Extracorporeal pulmonary support procedures in intensive care medicine 2014]. (2014) (1)
- Enhanced Cardiac CaMKII Oxidation and CaMKII-Dependent SR Ca Leak in Patients with Sleep-Disordered Breathing (2022) (1)
- Clinical/Translational Research Inhibition of Elevated Ca 2 /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium (2017) (1)
- [Molecular pathogenesis of heart failure]. (2006) (1)
- Nav1.8 Dysregulates Na and Ca Leading to Arrhythmias in Patients with Sleep-disordered Breathing. (2022) (1)
- Modulation of cardiac function by oxidized type I protein kinase A (2017) (1)
- Emergency coronary artery bypass surgery in the era of the FITT-STEMI project (2012) (1)
- Phosphorylation of RyR2 Ser‐2814 by CaMKII mediates β1‐adrenergic stress induced Ca2+‐leak from the sarcoplasmic reticulum (2021) (1)
- O-GlcNAcylation, oxidation and CaMKII contribute to atrial fibrillation in type 1 and type 2 diabetes by distinct mechanisms (2020) (1)
- Adaptive servo-ventilation in patients with chronic heart failure and sleep disordered breathing: predictors of usage (2020) (1)
- Acquired von Willebrand syndrome and factor VIII in patients with moderate to severe mitral regurgitation undergoing transcatheter mitral valve repair (2020) (1)
- IMPACT OF BODY MASS INDEX AND OBESITY ON CLINICAL OUTCOMES IN THE EDOXABAN VERSUS WARFARIN IN SUBJECTS UNDERGOING CARDIOVERSION OF ATRIAL FIBRILLATION (ENSURE-AF) RANDOMIZED TRIAL (2018) (1)
- Abstract 3838: Reduced Contact-to-Balloon Time in ST Elevation Myocardial Infarction as a Consequence of Formalized Data Analysis and Feedback: One-Year Results of the German Multicenter FITT-STEMI-Trial (2009) (1)
- Na+ channel regulation, structure, trafficking and sequestration (2015) (1)
- Transient hypoglycemia as a rare cause of recurring transient loss of consciousness: a case report (2021) (1)
- Central Sleep Apnea Is Associated with an Abnormal P-Wave Terminal Force in Lead V1 in Patients with Acute Myocardial Infarction Independent from Ventricular Function (2021) (1)
- Effects of Visualization of Revascularization on Symptomatic Outcomes in Patients With Chronic Coronary Syndrome. (2021) (1)
- Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor–dependent positive inotropy (2016) (1)
- CaMKIIδ Met281/282 oxidation is not required for recovery of calcium transients during acidosis. (2021) (1)
- Association of sleep-disordered breathing and disturbed cardiac repolarization in patients with ST-segment elevation myocardial infarction (2015) (1)
- S1. Kir2.1 expression in isolated ventricular cardiomyocytes of WT and KI mice. (2020) (0)
- Abstract 13658: Identification of Two Native Nav1.5 Phosphorylation Sites as Potential Determinants of the Increased Late Na+ Current in Heart Failure (2014) (0)
- Oxidized CaMKII Triggers Atrial Fibrillation Running title : (2013) (0)
- UC Davis Cardiovascular Symposium 2014 Systems Approach to Understanding Cardiac Excitation-Contraction Coupling and Arrhythmias — Na + channel and Na + transport (2014) (0)
- Cellular Reactive Oxygen Species–Activated Ca/Calmodulin Kinase II (cid:1) Is Required for Late I Na Augmentation Leading to Cellular Na and Ca Overload (2011) (0)
- Abstract 18454: Calcium Calmodulin Dependent Protein Kinase II delta Modulates Cardiomyocytes Passive Stiffness by Phosphorylating Titin Spring Elements (2012) (0)
- Erratum (2017) (0)
- Relationship Between Na (cid:49) -Ca 2 (cid:49) –Exchanger Protein Levels and Diastolic Function of Failing Human Myocardium (1999) (0)
- P5703Selective activation of cardiac protein phosphatase 1 is of antiarrhythmic potential in human diseased myocardium (2018) (0)
- The (cid:1) C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure (2003) (0)
- Abstract 183: Improved Ca-cycling by Dexamethasone Preserves Contractility After Ischemia/Reperfusion in Diabetic Rat Cardiomyocytes (2015) (0)
- CaMKII-Dependent Diastolic SR Ca 2 (cid:1) Leak and Elevated Diastolic Ca 2 (cid:1) Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation (2010) (0)
- P1092ROS-dependent store-operated Ca entry does not increase diastolic Ca in isolated ventricular myocytes (2017) (0)
- Clinical Research Prevalence of Sleep-Disordered Breathing-Related Symptoms in Patients with Chronic Heart Failure and Reduced Ejection Fraction (2015) (0)
- Abstract 3310: Therapeutic Hypothermia Improves Myocardial Function and Stabilizes Hemodynamic Parameters in Patients After Cardiac Arrest (2009) (0)
- Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity (2017) (0)
- SCN10A-knock-out improves survival and proarrhythmia in a transgenic heart failure mouse model (2020) (0)
- NEW METHODS IN CARDIOVASCULAR BIOLOGY (2015) (0)
- Abstract 3541: CaMKII Inhibition Improves Contractility in Human Failing Myocardium (2009) (0)
- Increased CaMKII-dependent pro-arrhythmic activity in a novel mouse model of obstructive sleep apnoea (2021) (0)
- Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4 (2017) (0)
- Høydal, M. A. et al. (2016) Exercise training reverses myocardial dysfunction induced by CaMKIIδC overexpression by restoring Ca2+- (2016) (0)
- Distinct phenotype patterns of Ca2+ handling proteins in end-stage failing human hearts (2000) (0)
- Increased NaV1.8 expression in patients with sleep-disordered breathing induces pro-arrhythmic activity (2021) (0)
- Correction to: The impact of epicardial adipose tissue in patients with acute myocardial infarction (2021) (0)
- Calcium/Calmodulin‐Dependent Protein Kinase II (CaMKII)—Modulation of Ion Currents and Potential Role for Arrhythmias (2009) (0)
- Association of sleep-disordered breathing and disturbed cardiac repolarization in patients with coronary artery bypass grafting (2017) (0)
- P3493Dexamethasone improves cardiac contractile force via SOCE activation (2017) (0)
- Predictors of postoperative delirium after elective coronary artery bypass grafting surgery in patients with and without sleep-disordered breathing – a prospective observational study (2019) (0)
- Abstract 2691: Persistent Atrial Fibrillation Causes Remodelling of Na Currents: Impact of INa Inhibition by Ranolazine on Arrhythmias and Contractility (2009) (0)
- 4966Targeting INaL by a neuronal sodium channel isoform improves survival in a CaMKII-transgenic heart failure mouse model (2019) (0)
- Abstract 16181: Ranolazine Reduces the Late Recurrences of Atrial Fibrillation. An Exploratory Analysis of the Raffaello Study (2014) (0)
- Acute kidney injury after elective coronary artery bypass grafting surgery in patients with and without sleep-disordered breathing (2019) (0)
- TCT-549 The “Me & My Heart” (eMocial) Study: A Randomized Evaluation of a New Smartphone-Based Support Tool to Increase Therapy Adherence of ACS patients (2019) (0)
- Subcellular mechanisms of delayed stretch-induced inotropy in rabbit myocardium (2002) (0)
- P5841PP1 activation as novel antiarrhythmic approach in human heart failure (2017) (0)
- Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases (2017) (0)
- In Silico Assessment of the Effect of Ca-Calmodulin Dependent Protein Kinase II (CaMKII) on Rabbit Ventricular Ion Currents and Action Potential (2007) (0)
- Inhibition of the Late Sodium Current with Ranolazine – A New Cardioprotective Mechanism (2008) (0)
- Atrial fibrillation impairs ventricular function by altering excitation-contraction coupling in the human heart (2020) (0)
- 266RBM20-dependent regulation of organized myofilament structure and titin splicing in induced pluripotent stem cell-derived cardiomyocytes from patients with dilative cardiomyopathy (2014) (0)
- Abstract 15993: Ablation of Phosphatase-1-Inhibitor-1 is Detrimental in CaMKII Overexpression Despite Reduction of SR Ca2+ Leak (2011) (0)
- P6283Inhibition of neuronal Na channel NaV1.8 reduces INaL and SR-Ca leak in isolated failing human and mouse ventricular cardiomyocytes (2017) (0)
- Abstract 5305: Knockout of the {delta} Isoform of CaMKII does not Negatively Influence Cardiomyocyte Excitation-Contraction Coupling in Mice (2008) (0)
- P3832Dantrolene reduces CaMKII-mediated arrhythmogenesis (2019) (0)
- Abstract 5324: Endurance Training Abolish Arrhythmogenic Calcium Leak In Cardiomyocytes From Mice With Transgenic Over-expression Of Camkii{delta}C (2008) (0)
- Abstract P186: Large Volume, Ice-cold Intravenous Fluid for Therapeutic Hypothermia Does Not Compromise the Respiratory Situation in Patients after Cardiac Arrest (2008) (0)
- Protected complex percutaneous coronary intervention and transcatheter aortic valve replacement using extracorporeal membrane oxygenation in a high-risk frail patient: a case report (2020) (0)
- Circulation: European Perspectives in Cardiology (2011) (0)
- [Acute Coronary Syndrome - What should the general practitioner do?] (2017) (0)
- Abstract 15705: Disordered Excitation Contraction Coupling as the Basis for Arrhythmogenic and Negative Inotropic Effects of Acute Ethanol Exposure (2016) (0)
- P3508A novel mouse model of sleep-disordered breathing is associated with contractile dysfunction and CaMKII overexpression (2019) (0)
- P4521C-reactive protein as a predictor for diastolic dysfunction in patients with sleep-disordered breathing (2019) (0)
- Abstract 2810: Increased Diastolic Calcium Levels Due to CaMKII-Dependent Sarcoplasmic Reticulum Calcium Leak in Patients With Atrial Fibrillation (2009) (0)
- Abstract 564: Gender Dependent Protective Effects of Melusin Overexpression on Post Myocardial Infarction Remodelling and Survival in Mice (2007) (0)
- Abstract 16339: Mitochondrial Function in Animal and Novel Human Disease Models of Tachycardiomyopathy (2020) (0)
- The adipo-fibrokine Activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in the obese (2019) (0)
- Abstract 521: Generation of Functional Cardiomyocytes from Adult Mouse Spermatogonial Stem Cells (2006) (0)
- An elevated late INa increases the diastolic SR-Ca-leak in atrial cardiomyocytes via a CaMKII-dependent mechanism (2013) (0)
- Titin Isoforms and Titin-Based Stiffness in Diastolic Heart Failure (2010) (0)
- handling in isolated rat myocardium 2+ Effects of left ventricular hypertrophy on force and Ca (2016) (0)
- Abstract 1414: Inhibition of Phosphatidylinositol 3-Kinase (PI3K) Improves Contractility in {alpha}-Adrenergic Stimulated Myocardium (2007) (0)
- Impact of sleep-disordered breathing on sternal wound complications after elective coronary artery bypass grafting surgery (2020) (0)
- Cellular mechanisms of early tachycardia-induced ventricular dysfunction in the human heart (2020) (0)
- Letter by Maier et al regarding article, "Emergency department bypass for ST-segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline Program". (2014) (0)
- Some 'brain' in the heart: a novel microdomain with neuronal Na channels responsible for arrhythmias? (2015) (0)
- P2833Sleep-disordered breathing is associated with enhanced CaMKII-dependent late INa and pro-arrhythmic activity (2018) (0)
- O-GlcNAcylation and oxidation contribute to atrial fibrillation in diabetes by activating CaMKII (2020) (0)
- Inhibition der CaMKII in Rektumkarzinomzellen (2014) (0)
- Endurance Training Abolish Arrhythmogenic Ca2+ Leak In Cardiomyocytes From Mice Over-expressing CaMKII (2009) (0)
- Young ambitious cardiologists and scientific research - reasons to get involved. (2009) (0)
- Rate Dependence of [Na (cid:1) ] i and Contractility in Nonfailing and Failing Human Myocardium (2002) (0)
- 3145Empagliflozin potently reduces sarcoplasmic Ca leak and increases Ca transient amplitude of human failing ventricular cardiomyocytes (2018) (0)
- CaMKII isoforms and calcineurin (2014) (0)
- Pulmonary complications after elective coronary artery bypass grafting surgery in patients with and without sleep-disordered breathing – a prospective observational study (2019) (0)
- CaMKII-Dependent Contractile Dysfunction and Pro-Arrhythmic Activity in a Mouse Model of Obstructive Sleep Apnea (2023) (0)
- Enhanced Heart Failure in Redox‐Dead Cys17Ser PKARIα Knock‐In Mice (2021) (0)
- Abstract 11041: Time Course of Recovery from Left Ventricular Systolic Dysfunction in Patients with Arrhythmia and Newly Diagnosed Heart Failure (2021) (0)
- Increasing mitochondrial Ca2+ uptake capacity enhances heart adaptation to pressure overload (2022) (0)
- Abstract 801: Differential Regulation Of Ca/calmodulin-dependent Protein Kinase II (CaMKII) In Cardiac Hypertrophy In The Mouse: Pressure Overload Versus Volume Overload (2007) (0)
- The proton pump inhibitor pantoprazole impairs contractility of human and rabbit myocardium (2005) (0)
- Current use and clinical benefit of intraaortic balloon support in patients with ST-elevation myocardial infarction complicated by cardiogenic shock (2013) (0)
- 0279: Phosphoproteomic identification of CAMKII- and SGK1-dependent phosphorylation sites on the native cardiac NAV1.5 channel protein in heart failure (2014) (0)
- Abstract 360: Ca/Calmodulin Kinase II (CaMKII) Overexpression Increases Effects of Reactive Oxygen Species to Enhance Late INa and Raise [Na 3]i and [Ca 2+]i (2007) (0)
- Abstract 1172: Inducible and Cardiac Specific Overexpression of the Neuronal NO Synthase (nNOS or NOS1) Enzyme in a New Transgenic Mouse Model (2006) (0)
- Abstract 17739: First Clinical Evaluation of a Novel Capacitive Electrocardiogram-System in Patients With Acute Myocardial Infarction (2010) (0)
- S tretch-dependent slow force response in isolated rabbit myocardium 1 is Na dependent (2003) (0)
- Cardiomyocyte Function Modulate Skeletal Muscle and To Expression and Fiber Type Composition SERCA2a Protein Kinases 2 and 3 Regulate Mitogen-Activated Protein Kinase-Activated (2013) (0)
- Response to Letter Regarding Article, “Differential Cardiac Remodeling in Preload Versus Afterload” (2011) (0)
- Echocardiographic Evaluation of LV Function in Patients with Tachyarrhythmia and Reduced Left Ventricular Function in Response to Rhythm Restoration (2021) (0)
- Irradiation Leads to Disturbed Excitation-Contraction Coupling in Cardiac Myocytes Through ROS-Dependent CaMKII Activation (2011) (0)
- P4711Contribution of neuronal sodium channel isoform Nav1.8 to enhanced proarrhythmic late sodium current in the human failing heart (2018) (0)
- Melusin protects from cardiac rupture and improves functional remodelling in mice after myocardial infarction (2013) (0)
- Results from the “Me & My Heart” (eMocial) Study: a Randomized Evaluation of a New Smartphone-Based Support Tool to Increase Therapy Adherence of Patients with Acute Coronary Syndrome (2022) (0)
- Abstract 19274: Coronary Artery Ectasia Are Frequently Observed in Patients With Bicuspid Aortic Valves With and Without Aneurysm of the Ascending Aorta (2014) (0)
- Abstract 17175: Phoshodiesterase 2 - A New Member Of Proteins Involved In Beta-adrenergic Desensitization (2013) (0)
- Myocyte Nitric Oxide Synthase 2 Contributes to Blunted (cid:1) -Adrenergic Response in Failing Human Hearts by Decreasing Ca 2 (cid:2) Transients (2004) (0)
- Sarcoplasmic Reticulum Ca / Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially (2013) (0)
- Abstract 2809: Knockout of Ca/Calmodulin Kinase IIδ Protects Against ROS-induced Injury (2009) (0)
- P5302SCN10A/NaV1.8 channels play a critical role in cellular electrophysiology and arrhythmogenesis of the failing human heart (2017) (0)
- [Proarrhythmic adverse effects of nonarrhythmic drugs]. (2019) (0)
- Explorer Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction (2017) (0)
- CaMKII delta interaction with neuronal sodium channel Nav1.8 contributes to arrhythmogenic triggers in failing human and mouse cardiomyocytes (2020) (0)
- Abstract 19515: CaMKII Oxidation Causes Increased Atrial Fibrillation in Diabetic Mice (2017) (0)
- Alternative Splicing of Cav1.2 in ARVC Patients (2020) (0)
- P5697Modulation of CaMKII-dependent proarrhythmias by inhibiting Nav1.8 in failing human and mouse ventricular cardiomyocytes (2018) (0)
- Overexpression of CaMKII (cid:1) c in RyR2 R4496C (cid:2) / (cid:3) Knock-In Mice Leads to Altered Intracellular Ca 2 (cid:2) Handling and Increased Mortality (2011) (0)
- 0062 : C-terminal phosphorylation of Nav1.5 channels impairs FGF13-dependent inactivation: potential impact in heart failure (2016) (0)
- Redox-activated protein kinase A Type I (PKA RI) exerts a protective role during pathological pressure overload (2020) (0)
- Abstract 356: CaMKII Cytoplasmic and Nuclear Isoforms Differentially Affect Calcium Handling but Similarly Regulate HDAC/MEF2 Transcriptional Responses (2006) (0)
- Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions (2022) (0)
- P1596Interaction of CaMKII and NaV1.8 modulates cardiac electrophysiology in human heart failure (2019) (0)
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What Schools Are Affiliated With Lars Siegfried Maier?
Lars Siegfried Maier is affiliated with the following schools: