Lars-Erik Tammelin
Swedish chemist
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Chemistry
Lars-Erik Tammelin's Degrees
- PhD Chemistry Uppsala University
- Masters Chemistry Uppsala University
Why Is Lars-Erik Tammelin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Lars-Erik Tammelin was a Swedish chemist, defence researcher and civil servant. Tammelin served as Director-General of the Swedish National Defence Research Institute from 1984 to 1985. Career Tammelin was born in Stockholm, Sweden, the son of Supreme Court Justice Erik Tammelin and his wife Elsa . Tammelin, who was an organic chemist, was recruited to the Swedish National Defence Research Institute in 1950 for research on nerve gas and nerve gas countermeasures. At this time, FOA had become aware that large quantities of nerve gas, primarily Tabun, had been stockpiled during World War II. The mechanism of action of the nerve gases were found to be linked to their chemical similarity to the neurotransmitter acetylcholine and their ability to block the enzyme cholinesterase. Much of Tammelin's work was therefore focussed on choline esters. In 1958, he defended a Ph.D. thesis based on this work at Stockholm University College. The same year he became Docent in organic chemistry at Stockholm University College.
Lars-Erik Tammelin's Published Works
Published Works
- Dialkoxy-phosphorylthiocholines, Alkoxy-methylphosphorylthiocholines, and Analogous Choline Esters. Synthesis, pKa of Tertiary Homologues, and Cholinesterase Inhibition. (1957) (58)
- An electrometric method for the determination of cholinesterase activity. II. Cholinesterase in brain tissue. (1953) (44)
- Methyl-fluoro-phosphorylcholines. Two Synthetic Cholinergic Drugs and Their Tertiary Homologues. (1957) (28)
- Calibration of an Electrometric Method for the Determination of Cholinesterase Activity. (1951) (21)
- Succinoylcholine Iodide (Celocurin): A Synthetic Drug with a Curare-like Effect. (1953) (19)
- On succinylcholine, a neuromuscular blocking drug, and its synergism with TEPP. (1951) (18)
- Organophosphorus Analogues of Tropic Acid Esters. 2. Tautomerism of Phenyl-diethoxyphosphoryl Acetaldehyde. (1961) (17)
- The action of anesthetics upon interfaces; on the mechanism of anesthesia. (1947) (15)
- Cholinesterase Activity Determined with an Electrometric Method. (1952) (13)
- Isomerisation of omega-Dimethylaminoethyl-diethylthionophosphate. (1957) (12)
- Microquantitative Determination of Calcium as Murexide Complex in the Presence of Magnesium. (1952) (12)
- Organophosphorus Analogues of Tropic Acid Esters. 1. 2-Phenyl-2-diethoxyphosphoryl Ethanol. (1960) (11)
- Synthesis of an Oxime Analogue to Atropin. (1961) (5)
- Syntheses of Choline Esters of Monobasic Carbonic Acids. (1956) (4)
- Acetic, Propionic, and Butyric Esters of 2-Dimethylaminoethanol, 2-Dimethylaminoethanethiol, and 2-Dimethylamino-1-methylethanol. (1957) (4)
- Choline esters : substrate and inhibitors of cholinesterases (1958) (3)
- An electrometric method for the determination of cholinesterase activity. I. Apparatus and cholinesterase in human blood. (1953) (2)
- [LT 1, a synthetic drug with effect similar to curare]. (1951) (1)
- Synthesis of Dimethylhydrazoniumethyl Esters of Aliphatic Dicarboxylic Acids. (1956) (1)
- Apparatus for the detection or discovery of impurities by means mounted on a state display element revolvably (1967) (0)
- Syntheses of p-Dimethylaminobenzyl Alcohol and Esters of its Methiodide. (1956) (0)
- [Eye irritations in pool bathing]. (1951) (0)
- The stability of acetyl-beta-methylcholine iodide (betacholyl) and succinylcholine iodide (celocurin) in solution. (1955) (0)
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