Laufey Ámundadóttir
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Icelandic cell biologist and geneticist
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Laufey Ámundadóttirbiology Degrees
Biology
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#19369
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Cell Biology
#888
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#911
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Genetics
#1887
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#2005
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Biology
Why Is Laufey Ámundadóttir Influential?
(Suggest an Edit or Addition)According to Wikipedia, Laufey Thora Ámundadóttir is an Icelandic cell biologist and geneticist who researches pancreatic cancer. She is a senior investigator in the laboratory of translational genomics at the National Cancer Institute. She was head of the division of cancer genetics at deCODE genetics from 1998 to 2007.
Laufey Ámundadóttir's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
- Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer (2009) (618)
- A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33 (2010) (542)
- Detectable clonal mosaicism and its relationship to aging and cancer (2012) (512)
- Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). (2010) (332)
- Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study (2017) (302)
- Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. (2009) (300)
- Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer (2014) (273)
- Identification of a new prostate cancer susceptibility locus on chromosome 8q24 (2009) (245)
- Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. (2010) (237)
- Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer (2015) (210)
- Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer (2018) (146)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. (2015) (133)
- Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (2013) (127)
- Family history of cancer and risk of pancreatic cancer: A pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan) (2010) (126)
- Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue (2014) (119)
- An Absolute Risk Model to Identify Individuals at Elevated Risk for Pancreatic Cancer in the General Population (2013) (116)
- Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer. (2012) (111)
- Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers (2008) (107)
- A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
- Characterization of large structural genetic mosaicism in human autosomes. (2015) (91)
- A population‐based familial aggregation analysis indicates genetic contribution in a majority of renal cell carcinomas (2002) (88)
- Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. (2014) (88)
- Two Susceptibility Loci Identified for Prostate Cancer Aggressiveness (2015) (88)
- Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas (2018) (84)
- Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21 (2016) (83)
- Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data (2016) (83)
- Variant ABO Blood Group Alleles, Secretor Status, and Risk of Pancreatic Cancer: Results from the Pancreatic Cancer Cohort Consortium (2010) (81)
- Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome (2016) (72)
- Genetic polymorphisms in the 9p21 region associated with risk of multiple cancers. (2014) (69)
- Pancreatic Cancer Genetics (2016) (66)
- Genome-wide association study of survival in patients with pancreatic adenocarcinoma (2012) (61)
- Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2019) (55)
- Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels (2011) (55)
- TERT gene harbors multiple variants associated with pancreatic cancer susceptibility (2015) (54)
- Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes (2017) (50)
- Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A. (2014) (46)
- A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer. (2020) (45)
- CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. (2014) (43)
- The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. (2000) (40)
- Large-scale exploration of gene-gene interactions in prostate cancer using a multistage genome-wide association study. (2011) (37)
- Quantifying the Genetic Correlation between Multiple Cancer Types (2017) (37)
- Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 (2017) (37)
- Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies (2010) (37)
- Pancreatic Cancer Risk Associated with Prediagnostic Plasma Levels of Leptin and Leptin Receptor Genetic Polymorphisms. (2016) (37)
- An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer (2013) (36)
- A comprehensive resequence analysis of the KLK15–KLK3–KLK2 locus on chromosome 19q13.33 (2009) (32)
- Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 (2018) (31)
- Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer (2016) (30)
- Circulating Metabolites and Survival Among Patients With Pancreatic Cancer. (2016) (30)
- The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients (2012) (28)
- Epidemiology and Inherited Predisposition for Sporadic Pancreatic Adenocarcinoma. (2015) (28)
- Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer (2020) (27)
- Association of Common Susceptibility Variants of Pancreatic Cancer in Higher-Risk Patients: A PACGENE Study (2016) (25)
- Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction (2013) (25)
- Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues (2017) (24)
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for 13 Cancer Types (2015) (24)
- Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression. (2016) (23)
- Pancreatic cancer risk is modulated by inflammatory potential of diet and ABO genotype: a consortia-based evaluation and replication study (2018) (22)
- CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells (2019) (21)
- Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer. (2018) (18)
- Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry (2012) (15)
- Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population (2020) (15)
- Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP (2014) (15)
- Variants Associated with Susceptibility to Pancreatic Cancer and Melanoma Do Not Reciprocally Affect Risk (2014) (14)
- DNA Methylation Levels at Chromosome 8q24 in Peripheral Blood Are Associated with 8q24 Cancer Susceptibility Loci (2014) (12)
- Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk (2017) (12)
- Prediagnostic Leukocyte Telomere Length and Pancreatic Cancer Survival (2019) (9)
- Impact of Sixteen Established Pancreatic Cancer Susceptibility Loci in American Jews (2017) (7)
- Endogenous Gastrin Collaborates With Mutant KRAS in Pancreatic Carcinogenesis. (2019) (7)
- A Resequence Analysis of Genomic Loci on Chromosomes 1q32.1, 5p15.33, and 13q22.1 Associated With Pancreatic Cancer Risk (2013) (7)
- A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer. (2021) (7)
- Assessing Disease Risk in Genome-wide Association Studies Using Family History (2012) (7)
- Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3 (2021) (6)
- The age-dependent association of risk factors with pancreatic cancer. (2022) (6)
- Hepcidin-regulating Iron-metabolism Genes and Pancreatic Ductal Adenocarcinoma: A Pathway Analysis of Genome-wide Association Studies (2020) (6)
- Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk (2020) (6)
- Genome-Wide Gene–Diabetes and Gene–Obesity Interaction Scan in 8,255 Cases and 11,900 Controls from PanScan and PanC4 Consortia (2020) (5)
- Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer (2011) (5)
- Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals (2021) (5)
- Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4 (2013) (4)
- Mendelian Randomization Analysis of n-6 Polyunsaturated Fatty Acid Levels and Pancreatic Cancer Risk (2020) (4)
- Abstract 1591: Large-scale transcriptome-wide association study (TWAS) identifies novel candidate susceptibility genes for pancreatic cancer (2019) (3)
- A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population (2020) (2)
- Correction: Vitamin D Metabolic Pathway Genes and Pancreatic Cancer Risk (2015) (2)
- A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer (2021) (1)
- Abstract 242: Large pathway and gene set analysis of GWAS data identifies novel associations for pancreatic cancer (2018) (1)
- The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714predict adverse outcome for breast cancer patients (2012) (1)
- Integrating gene expression and epidemiological data for the discovery of genetic interactions associated with cancer risk. (2014) (1)
- Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals (2021) (1)
- Abstract B89: Identification of dysregulated pathways in pancreatic cancer through gene set and subnetwork enrichment analyses of transcriptome and DNA methylome data. (2012) (1)
- Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
- Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) (1)
- Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer (2018) (1)
- Abstract 3461: Expression levels ofTOX3and the risk allele of the associated SNP rs3803662 predict adverse outcome for breast cancer patients. (2013) (1)
- Molecular and Cellular Pathobiology CLPTM 1 L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells (2014) (1)
- Genetic Susceptibility and Risk of Pancreatic Cancer (2014) (1)
- An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer (2013) (1)
- Mo1372 – Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductual Adenocarcinoma: A Pathway Analysis of Genome-Wide Association Studies (2019) (0)
- Abstract 4604: DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk (2015) (0)
- Abstract 2556: Functional characterization of the pancreatic cancer TERT-CLPTM1L risk locus on chr5p15.33. (2013) (0)
- Abstract 164: High-throughput epigenetic analysis of susceptibility loci identified by GWAS in pancreatic cancer (2010) (0)
- Abstract 1442: Analysis ofcis-eQTLs in normal and tumor-derived pancreatic tissues reveals functional insights, including for the 9q34.1ABOpancreatic cancer risk locus (2017) (0)
- Genome-Wide Analyses Characterize Shared Heritability Among Cancers and Identify Novel Cancer Susceptibility Regions. (2023) (0)
- Abstract 4610: Functional characterization of a multicancer risk locus on chr5p15.33 reveals regulation ofTERTby ZNF148 (2015) (0)
- Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression. (2016) (0)
- Abstract 5891: The age-dependent association of risk factors with pancreatic cancer (2022) (0)
- Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry (2012) (0)
- Abstract 1200: Associations between genetically predicted blood protein biomarkers and pancreatic ductal adenocarcinoma risk (2020) (0)
- Abstract 1295: Genomewide gene-diabetes and gene-obesity interaction scan in 7095 cases and 10710 controls from Pancreatic Cancer Cohort Consortium and Pancreatic Cancer Case Control Consortium (2017) (0)
- Abstract B112: Transcriptome analysis in pancreatic cancer reveals a tumor suppressor function for HNF1A (2015) (0)
- Abstract B111: Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects on DIS3 expression with prognostic implications (2015) (0)
- Abstract 287: Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue (2014) (0)
- Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448. (2023) (0)
- Genetic variants associated with PDAC also contribute to chronic pancreatitis susceptibility (2015) (0)
- Role of the Kennedy-phospholipid metabolism pathway in the genetic susceptibility of pancreatic ductal adenocarcinoma (2015) (0)
- Abstract 28: Characterization of SNPs associated with prostate cancer in men of Ashkenazic descent from the set of GWAS identified SNPs: Impact of cancer family history. (2012) (0)
- Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. (2023) (0)
- Abstract 1213: Genome-wide interaction scan identifies gene by smoking interaction at 2q21.3 for pancreatic cancer risk (2020) (0)
- Abstract 288: DNA methylation patterns in peripheral blood and the relationship with cancer susceptibility loci at chromosome 8q24 (2014) (0)
- Transcriptional regulation by NR5A2 couples cell differentiation and inflammation in the pancreas (2017) (0)
- Abstract 1170: MicroRNA gene polymorphisms in cancer susceptibility loci 5p12, 8q24 and 11q13 (2011) (0)
- Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (2012) (0)
- Pancreatic cancer genetics: Fine-mapping and functional characterization of the chr5p15.33/ CLPTM1L/TERT risk locus (2016) (0)
- puBlICatIons du personnel du CIrC 2008-2009 (2009) (0)
- Abstract IA-11: An exception to the rule: A coding functional variant at a pancreatic cancer GWAS locus (2020) (0)
- A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population (2020) (0)
- Novel pancreatic cancer susceptibility loci discovered through genome-wide association studies (2015) (0)
- Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4 (2013) (0)
- Abstract 3137: Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects onDIS3expression. (2013) (0)
- Abstract 1475: Uncovering the functional variants and target genes of the 7q32 pancreatic cancer risk locus (2022) (0)
- A Pathway Analysis of Hereditary Hemochromatosis-related Genes and Pancreatic Ductal Adenocarcinoma Risk (FS11-05-19). (2019) (0)
- Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases (2022) (0)
- Abstract 1194: Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions (2020) (0)
- The association between genetically elevated polyunsaturated fatty acids and risk of cancer (2023) (0)
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What Schools Are Affiliated With Laufey Ámundadóttir?
Laufey Ámundadóttir is affiliated with the following schools:
