Laurinda Jaffe
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American biologist
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Laurinda Jaffebiology Degrees
Biology
#14222
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#17922
Historical Rank
#2809
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Genetics
#1632
World Rank
#1740
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#314
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Molecular Biology
#2448
World Rank
#2486
Historical Rank
#258
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Biology
Laurinda Jaffe's Degrees
- Bachelors Biology University of California, Berkeley
- Masters Genetics Stanford University
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Why Is Laurinda Jaffe Influential?
(Suggest an Edit or Addition)According to Wikipedia, Laurinda A. Jaffe is an American biologist who is a Professor and chair at the University of Connecticut. Her research considers the physiological mechanisms that regulate oocyte cell and fertilisation. She was elected to the National Academy of Sciences in 2021.
Laurinda Jaffe's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte (2009) (458)
- Fast block to polyspermy in sea urchin eggs is electrically mediated (1976) (432)
- Egg activation at fertilization: where it all begins. (2002) (369)
- The Gs-Linked Receptor GPR3 Maintains Meiotic Arrest in Mammalian Oocytes (2004) (331)
- Electrical properties of egg cell membranes. (1979) (271)
- Meiotic Arrest in the Mouse Follicle Maintained by a Gs Protein in the Oocyte (2002) (241)
- Organization of the sea urchin egg endoplasmic reticulum and its reorganization at fertilization (1991) (237)
- Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption (2008) (230)
- Fertilization increases the polyphosphoinositide content of sea urchin eggs (1984) (200)
- Regulation of cortical vesicle exocytosis in sea urchin eggs by inositol 1,4,5-trisphosphate and GTP-binding protein (1986) (189)
- Calcium accumulations within the growing tips of pollen tubes (1975) (186)
- Reorganization of the endoplasmic reticulum during meiotic maturation of the mouse oocyte. (1995) (183)
- Actin, microvilli, and the fertilization cone of sea urchin eggs (1980) (169)
- Calcium Release at Fertilization in Starfish Eggs Is Mediated by Phospholipase Cγ (1997) (153)
- Development of calcium release mechanisms during starfish oocyte maturation. (1990) (147)
- 6 – Polyspermy-Preventing Mechanisms (1985) (137)
- Regulation of Mammalian Oocyte Meiosis by Intercellular Communication Within the Ovarian Follicle. (2017) (136)
- Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes. (2012) (135)
- SH2 domain-mediated activation of phospholipase Cgamma is not required to initiate Ca2+ release at fertilization of mouse eggs. (1998) (133)
- Electrically mediated fast polyspermy block in eggs of the marine worm, Urechis caupo (1979) (125)
- Fertilization events induced by neurotransmitters after injection of mRNA in Xenopus eggs. (1988) (125)
- Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles (2015) (123)
- Absence of an electrical polyspermy block in the mouse. (1983) (119)
- Structural change of the endoplasmic reticulum during fertilization: evidence for loss of membrane continuity using the green fluorescent protein. (1996) (110)
- Calcium Release at Fertilization of Xenopus Eggs Requires Type I IP3 Receptors, but Not SH2 Domain-Mediated Activation of PLCγ or Gq-Mediated Activation of PLCβ (1999) (109)
- Identification of PLCγ-Dependent and -Independent Events during Fertilization of Sea Urchin Eggs☆ (1999) (103)
- Stimulation of Xenopus oocyte maturation by inhibition of the G-protein alpha S subunit, a component of the plasma membrane and yolk platelet membranes (1995) (102)
- Electrical regulation of sperm-egg fusion. (1986) (102)
- Evidence for both tyrosine kinase and G-protein-coupled pathways leading to starfish egg activation. (1994) (99)
- Epidermal growth factor receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to LH. (2010) (97)
- Evidence that Gq family G proteins do not function in mouse egg activation at fertilization. (1998) (96)
- Requirement of a Src Family Kinase for Initiating Calcium Release at Fertilization in Starfish Eggs* 210 (1999) (96)
- Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein (2005) (95)
- Sperm extract injection into ascidian eggs signals Ca(2+) release by the same pathway as fertilization. (2000) (92)
- Structural changes in the endoplasmic reticulum of starfish oocytes during meiotic maturation and fertilization. (1994) (91)
- Maintenance of meiotic prophase arrest in vertebrate oocytes by a Gs protein-mediated pathway. (2004) (89)
- Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes (2014) (89)
- Ionic mechanism of the fertilization potential of the marine worm, Urechis caupo (Echiura) (1979) (88)
- The time course of cortical vesicle fusion in sea urchin eggs observed as membrane capacitance changes. (1978) (86)
- Ca2+ signalling during fertilization of echinoderm eggs. (2001) (85)
- Oocyte maturation in starfish is mediated by the beta gamma-subunit complex of a G-protein (1993) (84)
- Quantitative microinjection of oocytes, eggs, and embryos. (2004) (83)
- Membrane potential of the unfertilized sea urchin egg. (1978) (83)
- Pertussis toxin inhibits 1-methyladenine-induced maturation in starfish oocytes. (1989) (81)
- Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog, Xenopus laevis. (1991) (77)
- Evidence That Fertilization Activates Starfish Eggs by Sequential Activation of a Src-like Kinase and Phospholipase Cγ* (2000) (76)
- First messengers at fertilization. (1990) (73)
- Studies of the voltage-dependent polyspermy block using cross-species fertilization of amphibians. (1983) (72)
- A cholera toxin-sensitive G-protein stimulates exocytosis in sea urchin eggs. (1987) (69)
- Fertilization‐induced ionic conductances in eggs of the frog, Rana pipiens. (1985) (67)
- Evidence that phospholipase C from the sperm is not responsible for initiating Ca(2+) release at fertilization in mouse eggs. (2001) (64)
- Hormonal Coordination of Natriuretic Peptide Type C and Natriuretic Peptide Receptor 3 Expression in Mouse Granulosa Cells1 (2013) (59)
- Oocyte maturation in starfish is mediated by the βγ-subunit complex of a G-protein (1993) (55)
- Studies of the mechanism of the electrical polyspermy block using voltage clamp during cross-species fertilization (1982) (55)
- Structural changes of the endoplasmic reticulum of sea urchin eggs during fertilization. (1993) (51)
- Function of a sea urchin egg Src family kinase in initiating Ca2+ release at fertilization. (2003) (51)
- Evidence that the voltage-dependent component in the fertilization process is contributed by the sperm. (1989) (50)
- Propagating potassium and chloride conductances during activation and fertilization of the egg of the frog, Rana pipiens. (1985) (49)
- Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone. (2016) (48)
- SH2 domain-mediated activation of an SRC family kinase is not required to initiate Ca2+ release at fertilization in mouse eggs. (2005) (47)
- ELECTRICAL POLYSPERMY BLOCK IN SEA URCHINS: NICOTINE AND LOW SODIUM EXPERIMENTS 1 (1980) (46)
- Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta. (1999) (44)
- SH 2 Domain-Mediated Activation of Phospholipase C g Is Not Required to Initiate Ca 2 1 Release at Fertilization of Mouse Eggs (1998) (44)
- Egg Membranes during Fertilization (1996) (41)
- Meiotic resumption in response to luteinizing hormone is independent of a Gi family G protein or calcium in the mouse oocyte. (2006) (40)
- Imaging endoplasmic reticulum in living sea urchin eggs. (1993) (40)
- Activation by serotonin of starfish eggs expressing the rat serotonin 1c receptor. (1990) (38)
- Voltage sensitive phosphoinositide phosphatases of Xenopus: Their tissue distribution and voltage dependence (2011) (38)
- Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis (2016) (37)
- 12 – G-Proteins and the Regulation of Oocyte Maturation and Fertilization (1989) (35)
- Proteases stimulate fertilization-like responses in starfish eggs. (1995) (32)
- A receptor linked to a Gi-family G-protein functions in initiating oocyte maturation in starfish but not frogs. (2003) (31)
- A Gs-linked receptor maintains meiotic arrest in mouse oocytes, but luteinizing hormone does not cause meiotic resumption by terminating receptor-Gs signaling (2007) (30)
- Fertilization potential and polyspermy prevention in the egg of the nemertean, Cerebratulus lacteus. (1985) (30)
- Initiation of the Meiotic Prophase‐to‐Metaphase Transition in Mammalian Oocytes (2010) (30)
- A calcium-activated sodium conductance contributes to the fertilization potential in the egg of the nemertean worm Cerebratulus lacteus. (1986) (27)
- Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor (2017) (27)
- Microinjection of follicle-enclosed mouse oocytes. (2009) (27)
- G-proteins and egg activation. (1988) (27)
- Identification of PLCgamma-dependent and -independent events during fertilization of sea urchin eggs. (1999) (26)
- Localization of electrical excitability in the early embryo of Dentalium. (1981) (24)
- Dephosphorylation is the mechanism of fibroblast growth factor inhibition of guanylyl cyclase-B. (2017) (23)
- Electrical properties of vertebrate oocyte membranes. (1984) (20)
- A G(s)-linked receptor maintains meiotic arrest in mouse oocytes, but luteinizing hormone does not cause meiotic resumption by terminating receptor-G(s) signaling. (2007) (19)
- Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis. (2018) (18)
- Labeling of cell membranes and compartments for live cell fluorescence microscopy. (2004) (16)
- Receptors, G-proteins, and activation of the amphibian egg (1990) (15)
- Multiple cAMP Phosphodiesterases Act Together to Prevent Premature Oocyte Meiosis and Ovulation. (2018) (15)
- A calcium‐activated sodium conductance produces a long‐duration action potential in the egg of a nemertean worm. (1986) (14)
- Increased Expression of αqFamily G-proteins during Oocyte Maturation and Early Development ofXenopus laevis (1996) (13)
- The fast block to polyspermy: New insight into a century-old problem (2018) (13)
- Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles† (2019) (11)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (10)
- Cellular heterogeneity of the LH receptor and its significance for cyclic GMP signaling in mouse preovulatory follicles. (2020) (10)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (10)
- Receptors, G-Proteins, and Egg Activation (1989) (9)
- Regulation of Cortical Vesicle Exocytosis in Sea Urchin Eggs (1988) (9)
- The role of Src family kinases in starfish egg fertilisation (1999) (7)
- Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth (2021) (5)
- Kisspeptin-54 injection induces a physiological luteinizing hormone surge and ovulation in mice (2021) (4)
- Cellular heterogeneity of the LH receptor and its significance for cyclic GMP signaling in mouse preovulatory follicles (2020) (4)
- Increased Expression of a q Family G-proteins during Oocyte Maturation and Early Development of Xenopus laevis (1996) (3)
- Dating Weathering of Organic-rich Shales with U-Series Disequilibrium (2001) (2)
- Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian follicles† (2021) (2)
- The First Historical Eruption of Anatahan Volcano, Mariana Islands (2003) (2)
- Increased expression of alphaq family G-proteins during oocyte maturation and early development of Xenopus laevis. (1996) (2)
- Preparing for Fertilization: Intercellular Signals for Oocyte Maturation (2018) (1)
- Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase regulates oocyte meiotic resumption (2015) (1)
- Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles (2013) (1)
- A Voltage Sensitive Phosphatase from Xenopus Laevis Testis (2009) (1)
- The phosphatase inhibitor LB-100 acts synergistically with the NPR2 agonist BMN-111 to improve bone growth (2020) (1)
- Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles1 (2019) (1)
- Cyclic GMP from the somatic cells of the mouse ovarian follicle regulates cyclic AMP and meiosis in the oocyte (2009) (1)
- Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases (2022) (1)
- Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase regulates oocyte meiotic resumption (2015) (1)
- A calcium-activated sodium conductance contributes to the fertilization potential in the egg of the nemertean worm, Cerebratulus lacteus. (1986) (1)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (0)
- Dephosphorylation is the Mechanism of Fibroblast Growth Factor Inhibition of Guanylyl Cyclase-B (2017) (0)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (0)
- Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles (2013) (0)
- EGF Receptor Kinase Activity Is Required For Gap Junction Closure And For Part Of The Decrease In Ovarian Follicle cGMP In Response To Luteinizing Hormone (2017) (0)
- Author response: Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor (2017) (0)
- Shedding light on spawning in jellyfish (2018) (0)
- Luteinizing hormone stimulates ingression of granulosa cells within the mouse preovulatory follicle (2023) (0)
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