Lawrence I Grossman
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Engineering Computer Science
Lawrence I Grossman's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Lawrence I Grossman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Brain ischemia and reperfusion: molecular mechanisms of neuronal injury (2000) (795)
- Metabolic costs and evolutionary implications of human brain development (2014) (383)
- Evolution of increased glia–neuron ratios in the human frontal cortex (2006) (322)
- Evolution of the mammalian placenta revealed by phylogenetic analysis. (2006) (297)
- Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo (2003) (291)
- Proapoptotic BAX and BAK Modulate the Unfolded Protein Response by a Direct Interaction with IRE1a (2006) (270)
- Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles. (2004) (238)
- Regulation of mitochondrial respiration and apoptosis through cell signaling: cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation. (2012) (232)
- Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. (2013) (218)
- cAMP-dependent Tyrosine Phosphorylation of Subunit I Inhibits Cytochrome c Oxidase Activity* (2005) (194)
- A primate subfamily of galectins expressed at the maternal–fetal interface that promote immune cell death (2009) (187)
- Accelerated evolution of the electron transport chain in anthropoid primates. (2004) (184)
- Mammalian subunit IV isoforms of cytochrome c oxidase. (2001) (179)
- Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity (2017) (176)
- Genomics, biogeography, and the diversification of placental mammals (2007) (168)
- Comparative analysis of encephalization in mammals reveals relaxed constraints on anthropoid primate and cetacean brain scaling (2012) (140)
- Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2 (2013) (138)
- Nuclear genes for cytochrome c oxidase. (1997) (122)
- Cytochrome c oxidase of mammals contains a testes‐specific isoform of subunit VIb—the counterpart to testes‐specific cytochrome c? (2003) (117)
- Global brain ischemia and reperfusion. (1996) (115)
- Tissue‐specific regulation of cytochrome c by post‐translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis (2018) (114)
- MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. (2015) (113)
- Mitochondrial genetics and human disease (1996) (107)
- Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease. (2012) (104)
- Moving primate genomics beyond the chimpanzee genome. (2005) (101)
- Evolution of nuclear- and mitochondrial-encoded subunit interaction in cytochrome c oxidase. (2001) (100)
- Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase. (1987) (97)
- New prospects for an old enzyme: mammalian cytochrome c is tyrosine-phosphorylated in vivo. (2006) (96)
- Cytochrome c oxidase: evolution of control via nuclear subunit addition. (2012) (94)
- Molecular evolution of aerobic energy metabolism in primates. (2001) (86)
- Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease (2017) (84)
- Dolphin genome provides evidence for adaptive evolution of nervous system genes and a molecular rate slowdown (2012) (83)
- Adaptive evolution of cytochrome c oxidase subunit VIII in anthropoid primates (2003) (83)
- Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing (2017) (79)
- Aerobic glycolysis in the primate brain: reconsidering the implications for growth and maintenance (2014) (77)
- Phylogenomic analyses reveal convergent patterns of adaptive evolution in elephant and human ancestries (2009) (74)
- Emergence of hormonal and redox regulation of galectin-1 in placental mammals: Implication in maternal–fetal immune tolerance (2008) (74)
- Rapid electrostatic evolution at the binding site for cytochrome c on cytochrome c oxidase in anthropoid primates. (2005) (74)
- Developmental changes in the transcriptome of human cerebral cortex tissue: long noncoding RNA transcripts. (2014) (70)
- Cytochrome c oxidase subunit 4 isoform 2‐knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology (2012) (68)
- Molecular evolution of cytochrome c oxidase subunit I in primates: is there coevolution between mitochondrial and nuclear genomes? (2000) (62)
- Transcription of mammalian cytochrome c oxidase subunit IV‐2 is controlled by a novel conserved oxygen responsive element (2007) (62)
- Molecular Evolution of Cytochrome c Oxidase Subunit IV: Evidence for Positive Selection in Simian Primates (1997) (61)
- Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis. (2020) (59)
- Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase. (1992) (59)
- Tissue-specific genes for respiratory proteins. (1989) (58)
- Cytochrome c Oxidase Subunit VIIa Liver Isoform (1996) (55)
- A third isoform of cytochrome c oxidase subunit VIII is present in mammals. (2003) (55)
- Structural Organization and Promoter Analysis of the Bovine Cytochrome c Oxidase Subunit VIIc Gene (1997) (54)
- Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution (2008) (51)
- Molecular evolution of the cytochrome c oxidase subunit 5A gene in primates (2008) (48)
- Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury (2018) (48)
- Molecular evolution of the COX7A gene family in primates. (1999) (46)
- Cytochrome c oxidase subunit VIIa isoforms. Characterization and expression of bovine cDNAs. (1991) (45)
- Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors (2019) (44)
- A Primate Genome Project Deserves High Priority (2000) (41)
- Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney (2016) (40)
- Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase. (1989) (39)
- Dynamic Gene Expression in the Human Cerebral Cortex Distinguishes Children from Adults (2012) (38)
- Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy. (2012) (37)
- Coadaptive evolution in cytochrome c oxidase: 9 of 13 subunits show accelerated rates of nonsynonymous substitution in anthropoid primates. (2004) (36)
- Isolation and characterization of a cDNA clone for bovine cytochrome c oxidase subunit IV. (1984) (36)
- The human progesterone receptor shows evidence of adaptive evolution associated with its ability to act as a transcription factor. (2008) (36)
- COX7AR is a Stress-inducible Mitochondrial COX Subunit that Promotes Breast Cancer Malignancy (2016) (35)
- The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction (2018) (35)
- Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis (2015) (34)
- Mitochondrial DNA in sickness and in health. (1990) (34)
- Two bovine genes for cytochrome c oxidase subunit IV: a processed pseudogene and an expressed gene. (1987) (33)
- Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation (2019) (32)
- Molecular evolution of cytochrome c oxidase: rate variation among subunit VIa isoforms. (1997) (31)
- HIF-1α regulates IL-1β and IL-17 in sarcoidosis (2019) (31)
- Deletion of heart‐type cytochrome c oxidase subunit 7a1 impairs skeletal muscle angiogenesis and oxidative phosphorylation (2012) (30)
- Sequence of a cDNA specifying subunit VIIc of human cytochrome c oxidase. (1990) (29)
- The brown and brite adipocyte marker Cox7a1 is not required for non-shivering thermogenesis in mice (2015) (26)
- Current relaxation of selection on the human genome: tolerance of deleterious mutations on olfactory receptors. (2013) (26)
- Rapid evolution of the human gene for cytochrome c oxidase subunit IV. (1992) (25)
- Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV. (1990) (23)
- Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration. (2017) (23)
- Evolution of the couple cytochrome c and cytochrome c oxidase in primates. (2012) (23)
- Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms (2020) (21)
- Studies of the protein synthesis system in the brain cortex during global ischemia and reperfusion. (1993) (21)
- Brain nuclear DNA survives cardiac arrest and reperfusion. (1991) (21)
- Mitochondrial mutations and human disease (1995) (21)
- Episodic positive selection in ape cytochrome c oxidase subunit IV. (2002) (20)
- Nucleotide sequence of a cDNA for bovine cytochrome c oxidase subunit VIIa. (1989) (20)
- The 5′ region of the COX4 gene contains a novel overlapping gene, NOC4 (1999) (20)
- Synaptosomal Lactate Dehydrogenase Isoenzyme Composition Is Shifted toward Aerobic Forms in Primate Brain Evolution (2014) (19)
- Amino acid replacement is rapid in primates for the mature polypeptides of COX subunits, but not for their targeting presequences. (2002) (19)
- Mitochondrial DNAs of Suillus: three fold size change in molecules that share a common gene order (2004) (19)
- Brain Mitochondrial DNA Is Not Damaged by Prolonged Cardiac Arrest or Reperfusion (1992) (19)
- Tissue-specific expression and mapping of the Cox7ah gene in mouse. (1998) (18)
- MNRR1, a Biorganellar Regulator of Mitochondria (2017) (18)
- Structural organization and evolution of the liver isoform gene for bovine cytochrome c oxidase subunit VIIa. (1993) (17)
- Serine‐47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase‐3 activity (2016) (17)
- Mitochondrial autoimmunity and MNRR1 in breast carcinogenesis (2019) (17)
- The cDNA for the heart/muscle isoform of bovine cytochrome c oxidase subunit VIa encodes a presequence. (1991) (16)
- Cloning, sequence analysis, and expression of a mouse cDNA encoding cytochrome c oxidase subunit VIa liver isoform. (1995) (15)
- Genomic organization and promoter regulation of human cytochrome c oxidase subunit VII heart/muscle isoform (COX7AH). (2002) (14)
- Retention of a Duplicate Gene Through Changes in Subcellular Targeting: An Electron Transport Protein Homologue Localizes to the Golgi (2003) (14)
- Isolation and sequence of the human cytochrome c oxidase subunit VIIaL gene. (2000) (14)
- Transcriptional regulation of mammalian cytochrome c oxidase genes (1998) (13)
- Silencing, Positive Selection and Parallel Evolution: Busy History of Primate Cytochromes c (2011) (13)
- Cytochrome c Oxidase Subunit VIIa Liver Isoform CHARACTERIZATION AND IDENTIFICATION OF PROMOTER ELEMENTS IN THE BOVINE GENE* (1996) (13)
- OCPAT: an online codon-preserved alignment tool for evolutionary genomic analysis of protein coding sequences (2007) (12)
- Nucleotide sequence of a mouse cDNA for subunit IV of cytochrome c oxidase. (1990) (11)
- Nucleotide sequence of a cDNA for mouse cytochrome c oxidase subunit VIIc. (1990) (8)
- Divergent lactate dehydrogenase isoenzyme profile in cellular compartments of primate forebrain structures (2017) (8)
- Rapid Nonsynonymous Evolution of the Iron-Sulfur Protein in Anthropoid Primates (2005) (8)
- Nucleotide sequence of cDNA encoding subunit VIIa of rat liver cytochrome c oxidase. (1990) (8)
- Regulation of cytochrome c in respiration, apoptosis, neurodegeneration and cancer: The good, the bad and the ugly (2014) (6)
- Regulation of COX Assembly and Function by Twin CX9C Proteins—Implications for Human Disease (2021) (6)
- Characterization of human cortical gene expression in relation to glucose utilization (2013) (6)
- Characterization and expression of a cDNA specifying subunit VIIc of bovine cytochrome c oxidase. (1991) (6)
- Mitochondrial respiration is controlled by Allostery, Subunit Composition and Phosphorylation Sites of Cytochrome c Oxidase: A trailblazer's tale - Bernhard Kadenbach. (2021) (6)
- Structure and organization of the heart isoform gene for bovine cytochrome c oxidase subunit VIIa. (1992) (5)
- Human testis-specific genes are under relaxed negative selection (2014) (5)
- Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines (2015) (5)
- Publisher Correction: Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury (2018) (4)
- Mitogroup: continent-specific clusters of mitochondrial OXPHOS complexes based on nuclear non-synonymous polymorphisms. (2012) (4)
- Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1nmf164. (2019) (4)
- Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy. (2021) (4)
- A rapid protocol to isolate DNA fragments from low melting temperature agarose. (1991) (4)
- Fetal and maternal NLRP3 signaling is required for preterm labor and birth (2022) (3)
- Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review (2020) (3)
- High‐throughput RNA sequencing reveals structural differences of orthologous brain‐expressed genes between western lowland gorillas and humans (2016) (2)
- Author response: HIF-1α regulates IL-1β and IL-17 in sarcoidosis (2019) (2)
- Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway (2022) (2)
- Potential Role of Growth Factors in Global Brain Ischemia and Reperfusion: Observation of Insulin‐Driven Tyrosine Phosphorylation of a 90‐kDa Protein during Reperfusion a (1993) (2)
- Chapter X. Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease (2013) (1)
- Lipopolysaccharide induces placental mitochondrial dysfunction by reducing MNRR1 levels via a TLR4-independent pathway (2021) (1)
- Reply to Skoyles: Decline in growth rate, not muscle mass, predicts the human childhood peak in brain metabolism (2014) (1)
- Antisense inhibition of nuclear-encoded cytochrome c oxidase subunits IV and VIIc activity in the pre-implantation embryo. (1993) (1)
- Erratum: Tissue-specific expression and mapping of the Cox7ah gene in mouse (Genomics (1998) 49:3 (363-370)) (1998) (1)
- Nucleotide sequence of a cDNA for bovine cytochrome c oxidase subunit VIIc. (1989) (1)
- Supplementary Material for: Synaptosomal Lactate Dehydrogenase Isoenzyme Composition Is Shifted toward Aerobic Forms in Primate Brain Evolution (2017) (1)
- CHCHD2, a bi-genomic regulator of mitochondrial metabolism (2013) (1)
- Corrigendum to "Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1nmf164" [Mitochondrion 51 (2019) 15-21]. (2021) (1)
- Regulation of Cytochrome C by Phosphorylation: Mitochondrial Respiration and Apoptosis (2017) (1)
- Insulin Induces Tyrosine Phosphorylation of a 90-kDa Protein during Postischemic Brain Reperfusion (1993) (1)
- Human testis-specific genes are under relaxed negative selection (2013) (0)
- Evidence for the participation of CHCHD2/MNRR1, a mitochondrial protein, in spontaneous labor at term and in preterm labor with intra-amniotic infection. (2023) (0)
- MNRR1 is a driver of ovarian cancer progression (2023) (0)
- Oxygen regulation of cytochrome oxidase subunit 4–2 (2011) (0)
- Essential Role of Mitochondrial Cytochrome c Oxidase Subunit 4 Isoform 2 (Cox4i2) for Acute Pulmonary Oxygen Sensing (2022) (0)
- Aerobic glycolysis in the primate brain: reconsidering the implications for growth and maintenance (2013) (0)
- CX9C proteins: Stress-responsive IMS regulators and disease modifiers (2015) (0)
- The COX7A gene family: Organization, evolution, and function (1998) (0)
- Adaptive evolution of cis‐regulatory regions among genes dynamically expressed in the juvenile human cortex (89.8) (2014) (0)
- The high metabolic costs of human brain development help explain the unusually slow body growth of human childhood (2015) (0)
- Cytochrome c is phosphorylated by AMP kinase in mammalian kidney, leading to controlled electron transport chain flux (2016) (0)
- Accelerated evolution of genes and neocortical expansion in mammalian lineages (2005) (0)
- The role of Mitochondrial Superoxide Release in Acute and Chronic Hypoxia Sensing and Signaling of the Pulmonary vasculature (2018) (0)
- MNRR1 activation by nitazoxanide abrogates lipopolysaccharide-induced preterm birth in mice (2023) (0)
- Non-invasive modulation of cytochrome c oxidase activity with specific infrared light for the treatment of reperfusion injury (2012) (0)
- Subunit coevolution of cytochrome c oxidase in primates (1997) (0)
- Mitochondrial autoimmunity and MNRR1 in breast carcinogenesis (2019) (0)
- Inhalation Exposure to Airborne PM2.5Induces Integrated Organelle Stress Response in the Liver (2022) (0)
- The role of cytochrome c oxidase subunit 4 isoform 2 (Cox4i2) in chronic hypoxia induced pulmonary hypertension (2016) (0)
- YME1L1 and MNRR1 (CHCHD2): Stress responsive regulation of an OxPhos regulator (2016) (0)
- Wolbachia: Interactions with Mitochondria Inside the Cell (2017) (0)
- Non-coding regions of nuclear-DNA-encoded mitochondrial genes and intergenic sequences are targeted by autoantibodies in breast cancer (2023) (0)
- Control of Electron Transport Chain Flux by Cytochrome c Threonine 28 phosphorylation in Kidney: Implications for AMP Kinase (2016) (0)
- Gene regulation of cytochrome c oxidase subunit 4 isoform 2: A tale of three factors (2012) (0)
- Publisher Correction: Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury (2018) (0)
- Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury (2018) (0)
- Functional genetic differences among humans, chimpanzees, and their closest relatives (2002) (0)
- CX9C proteins as new stress-responsive bi-organellar regulators and disease modifiers (2015) (0)
- Intraperitoneal Triamcinolone Reduces Postoperative Adhesions, Possibly through Alteration of Mitochondrial Function (2022) (0)
- Mitochondrial oxygen sensing of acute hypoxia in specialized cells - is there an unifying mechanism? (2022) (0)
- 07.03CX9C isoform proteins as bi-organellar modifiers of mitochondrial function and stress response (2016) (0)
- Abstract 26: Role of Cytochrome c Oxidase Subunit 4- Isoform 2 in Neuronal Susceptibility to Lethal Ischemia/Reperfusion-Induced Injury (2012) (0)
- DAVID output (top 5% dN/dS) (2009) (0)
- An explanation for the decreased severity of liver malfunction in Niemann-Pick C1 disease with age (2022) (0)
- Transcriptional patterns of ATP-synthase subunits in rat liver and muscle tissues during development (2012) (0)
- Brain DNA survives ischemia and reperfusion (1990) (0)
- Letter by Hüttemann et al Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction". (2019) (0)
- Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis (2015) (0)
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What Schools Are Affiliated With Lawrence I Grossman?
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