Lawrence A Loeb

Q: What Schools Are Affiliated With Lawrence A Loeb

Lawrence A Loeb is affiliated with the following schools: University of California, Berkeley, Yale University, California Institute of Technology, University of Tsukuba, Massachusetts Institute of Technology, Stanford University, University of Washington, University of California, San Francisco

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Lawrence A Loeb

Biology

#2839

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#4434

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Cell Biology

#56

World Rank

#60

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Molecular Biology

#181

World Rank

#185

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Genetics

#184

World Rank

#226

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Biology

Lawrence A Loeb's Degrees

Bachelors Biology University of California, Berkeley
PhD Molecular Biology Stanford University

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Lawrence A Loeb's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. (1992) (1786)
Mutator phenotype may be required for multistage carcinogenesis. (1991) (1407)
Fidelity of HIV-1 reverse transcriptase. (1988) (937)
Mutagenesis by apurinic/apyrimidinic sites. (1986) (866)
A mutator phenotype in cancer. (2001) (809)
Detection of ultra-rare mutations by next-generation sequencing (2012) (775)
Multiple mutations and cancer (2003) (757)
The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. (2001) (624)
Environmental and chemical carcinogenesis. (2004) (602)
The Werner syndrome protein is a DNA helicase (1997) (586)
Microsatellite instability: marker of a mutator phenotype in cancer. (1994) (574)
Errors in DNA replication as a basis of malignant changes. (1974) (513)
Reactive oxygen species in tumorigenesis. (1994) (493)
Fidelity of DNA synthesis. (1982) (444)
Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens. (1976) (432)
Significance of multiple mutations in cancer. (2000) (419)
The mutation rate and cancer. (1998) (417)
Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging (2009) (406)
Human cancers express mutator phenotypes: origin, consequences and targeting (2011) (377)
Human cancers express a mutator phenotype (2006) (377)
Mitochondrial point mutations do not limit the natural lifespan of mice (2007) (363)
Lethal mutagenesis of HIV with mutagenic nucleoside analogs. (1999) (362)
Human Werner Syndrome DNA Helicase Unwinds Tetrahelical Structures of the Fragile X Syndrome Repeat Sequence d(CGG) n * (1999) (362)
Detecting ultralow-frequency mutations by Duplex Sequencing (2014) (327)
The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure. (1994) (320)
Protein tolerance to random amino acid change. (2004) (301)
Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations (2018) (298)
Smoking and lung cancer: an overview. (1984) (291)
Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy. (1996) (289)
Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage (2013) (284)
Advances in chemical carcinogenesis: a historical review and prospective. (2008) (280)
Infidelity of DNA synthesis associated with bypass of apurinic sites. (1983) (267)
DNA polymerases and human disease (2008) (262)
Apurinic sites as mutagenic intermediates (1985) (259)
Mutagenic spectrum resulting from DNA damage by oxygen radicals. (1991) (250)
Induction of microsatellite instability by oxidative DNA damage. (1998) (241)
Animal Cell Dna Polymerases (1986) (235)
Cancer cells exhibit a mutator phenotype. (1998) (231)
The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. (2005) (222)
Viral error catastrophe by mutagenic nucleosides. (2004) (218)
Cancers exhibit a mutator phenotype: clinical implications. (2008) (212)
Interactions between the Werner Syndrome Helicase and DNA Polymerase δ Specifically Facilitate Copying of Tetraplex and Hairpin Structures of the d(CGG) n Trinucleotide Repeat Sequence* (2001) (211)
Accuracy of Next Generation Sequencing Platforms. (2014) (210)
Zinc in DNA polymerases. (1971) (210)
Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. (1998) (209)
Fidelity of HIV-1 reverse transcriptase copying RNA in vitro. (1992) (208)
Werner Syndrome Protein (1998) (206)
On the fidelity of DNA replication: manganese mutagenesis in vitro. (1985) (198)
Endogenous carcinogenesis: molecular oncology into the twenty-first century--presidential address. (1989) (196)
Werner Syndrome Protein (1998) (193)
Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selection. (2001) (189)
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. (1994) (188)
Somatic mutations in aging, cancer and neurodegeneration (2012) (187)
Genomic instability and tumor progression: mechanistic considerations. (1993) (184)
Purification and properties of deoxyribonucleic acid polymerase from nuclei of sea urchin embryos. (1969) (180)
On the fidelity of DNA replication. (1979) (180)
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro (1989) (179)
The influence of subclonal resistance mutations on targeted cancer therapy (2016) (177)
Functional interaction between the Werner Syndrome protein and DNA polymerase delta. (2000) (172)
The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases. (2000) (172)
Mutagenesis by the autoxidation of iron with isolated DNA. (1988) (164)
Depurination causes mutations in SOS-induced cells. (1981) (163)
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I (2003) (163)
Genetic instability in cancer: theory and experiment. (2005) (162)
Tandem double CC-->TT mutations are produced by reactive oxygen species. (1993) (148)
Fidelity of mammalian DNA polymerases. (1981) (148)
Escherichia coli deoxyribonucleic acid polymerase I, a zinc metalloenzyme. Nuclear quadrupolar relaxation studies of the role of bound zinc. (1973) (147)
An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy (2013) (144)
Mutation spectrum of copper-induced DNA damage. (1991) (143)
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice (2008) (139)
Genetic Constraints on Protein Evolution (2007) (132)
The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53* 210 (2002) (130)
The infidelity of avian myeloblastosis virus deoxyribonucleic acid polymerase in polynucleotide replication. (1974) (128)
Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues (2016) (128)
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. (1986) (121)
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. (1989) (119)
On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis. (1979) (118)
ZINC REQUIREMENT FOR DNA REPLICATION IN STIMULATED HUMAN LYMPHOCYTES (1973) (117)
An RNA polymerase mutant with reduced accuracy of chain elongation. (1986) (116)
Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro. (1983) (114)
Identification and purification of sheep platelet phospholipase A2 isoforms. Activation by physiologic concentrations of calcium ion. (1986) (113)
Sequencing small genomic targets with high efficiency and extreme accuracy (2015) (113)
Deregulated DNA polymerase β induces chromosome instability and tumorigenesis (2002) (110)
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. (1991) (110)
Mutation at the Polymerase Active Site of Mouse DNA Polymerase δ Increases Genomic Instability and Accelerates Tumorigenesis (2007) (109)
Unwinding the molecular basis of the Werner syndrome (2001) (109)
A Single Highly Mutable Catalytic Site Amino Acid Is Critical for DNA Polymerase Fidelity* (2001) (109)
Multiple Amino Acid Substitutions Allow DNA Polymerases to Synthesize RNA* (2000) (106)
Mutagenesis during in vitro DNA synthesis. (1978) (105)
Nucleotide sequence preservation of human mitochondrial DNA. (1985) (105)
DNA polymerase delta in dna replication and genome maintenance (2012) (105)
DNA polymerase active site is highly mutable: evolutionary consequences. (2000) (105)
Differential extension of 3' mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-alpha. (1989) (104)
Fidelity of HIV-1 reverse transcriptase copying a hypervariable region of the HIV-1 env gene. (1994) (102)
Current advances in unraveling the function of the Werner syndrome protein. (2005) (101)
Quantification of random genomic mutations (2005) (98)
Human Immunodeficiency Virus Reverse Transcriptase (1996) (98)
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA. (2000) (96)
Mutational heterogeneity in human cancers: origin and consequences. (2010) (93)
Efficiency of carcinogenesis with and without a mutator mutation (2006) (93)
High fidelity and lesion bypass capability of human DNA polymerase delta. (2009) (92)
Metal-induced infidelity during DNA synthesis. (1976) (91)
Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli. (1992) (88)
Optimization of DNA polymerase mutation rates during bacterial evolution (2009) (86)
APOBEC3B mutagenesis in cancer (2013) (86)
DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae. (1994) (85)
Mutations induced by methylene blue plus light in single-stranded M13mp2. (1992) (84)
Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma (2017) (83)
On the fidelity of DNA replication. Effect of the next nucleotide on proofreading. (1981) (83)
Getting a grip on how DNA polymerases function (2001) (82)
Mutator Phenotypes Caused by Substitution at a Conserved Motif A Residue in Eukaryotic DNA Polymerase δ* (2006) (82)
Delayed and reduced cell replication and diminishing levels of DNA polymerase‐α in regenerating liver of aging mice (1984) (80)
Incorporation of the Guanosine Triphosphate Analogs 8-Oxo-dGTP and 8-NH2-dGTP by Reverse Transcriptases and Mammalian DNA Polymerases* (1997) (80)
Sea urchin nuclear DNA polymerase. II. Changing localization during early development. (1969) (79)
Werner Syndrome Protein II . CHARACTERIZATION OF THE INTEGRAL 3 9 3 5 9 DNA EXONUCLEASE * (1998) (78)
Genetic instability and the mutator phenotype. Studies in ulcerative colitis. (1999) (78)
Mutagenic specificity of oxygen radicals produced by human leukemia cells. (1992) (77)
Mutator phenotype in cancer: Timing and perspectives (2005) (77)
On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase. (1977) (76)
Human Cancers Express a Mutator Phenotype: Hypothesis, Origin, and Consequences. (2016) (76)
Effects of arsenic, selenium, and chromium on the fidelity of DNA synthesis. (1980) (75)
An E. coli promoter that regulates transcription by DNA superhelix-induced cruciform extrusion. (1988) (75)
Mutagenesis by metal-induced oxygen radicals. (1994) (75)
Lethal mutagenesis: targeting the mutator phenotype in cancer. (2010) (74)
Promoters selected from random DNA sequences. (1986) (74)
DNA polymerase activity as an index of lymphocyte stimulation: studies in Down's syndrome. (1970) (74)
Mutation of HIV-1 Genomes in a Clinical Population Treated with the Mutagenic Nucleoside KP1461 (2011) (74)
AUSTRALIA ANTIGEN (A HEPATITIS-ASSOCIATED ANTIGEN) PURIFICATION AND PHYSICAL PROPERTIES (1970) (73)
Induction of DNA polymerase in human lymphocytes by phytohemagglutinin. (1968) (73)
Low Fidelity Mutants in the O-Helix of Thermus aquaticus DNA Polymerase I* (1997) (73)
Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs. (2000) (73)
Metal activation of DNA synthesis. (1976) (73)
Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. (2002) (73)
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals. (1972) (72)
I. DNA HELICASE AND DNA EXONUCLEASE RESIDE ON THE SAME POLYPEPTIDE (1998) (72)
Improving enzymes for cancer gene therapy (1999) (72)
Destabilization of tetraplex structures of the fragile X repeat sequence (CGG)n is mediated by homolog-conserved domains in three members of the hnRNP family. (2004) (71)
Thermus aquaticus DNA Polymerase I Mutants with Altered Fidelity (2000) (71)
Cancer genome sequencing--an interim analysis. (2009) (70)
On the fidelity of transcription by Escherichia coli ribonucleic acid polymerase. (1975) (68)
Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure. (1996) (68)
The Werner Syndrome Protein Binds Replication Fork and Holliday Junction DNAs as an Oligomer* (2008) (68)
Effects of depurination on the fidelity of DNA synthesis. (1979) (68)
Multiple mutations in human cancers. (1996) (68)
Sea urchin nuclear DNA polymerase. (1974) (68)
Single-strand binding protein enhances fidelity of DNA synthesis in vitro. (1979) (66)
6. Eucaryotic DNA Polymerases (1974) (66)
A cryptic proofreading 3'----5' exonuclease associated with the polymerase subunit of the DNA polymerase-primase from Drosophila melanogaster. (1987) (65)
Quantification of random mutations in the mitochondrial genome. (2008) (65)
Nickel induces a signature mutation for oxygen free radical damage. (1993) (65)
Copying natural RNAs with E. coli DNA polymerase I. (1973) (65)
Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: analysis of selected mutants in vitro. (1993) (63)
Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha. (1983) (63)
On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase. (1976) (63)
Retroviral reverse transcriptases: error frequencies and mutagenesis. (1992) (62)
Clonal expansions in ulcerative colitis identify patients with neoplasia (2009) (62)
Studies on the mechanism of drug-induced microsomal enzyme activities. V. Phenobarbital stimulation of endogenous messenger RNA and polyuridylic acid-directed L-[14C]-phenylalanine incorporation. (1966) (62)
Lethal mutagenesis of HIV. (2005) (62)
Rapid changes in deoxynucleoside triphosphate pools in mammalian cells treated with mutagens. (1983) (61)
Differential heat sensitivity of mammalian DNA polymerases. (1977) (61)
Errors in DNA synthesis: a source of spontaneous mutations. (1990) (61)
Mechanisms of mutation by oxidative DNA damage: reduced fidelity of mammalian DNA polymerase beta. (1993) (60)
DNA polymerase and DNA replication during lymphocyte transformation. (1970) (60)
Do mutator mutations fuel tumorigenesis? (2013) (60)
Implications of genetic heterogeneity in cancer (2012) (60)
Mutations in human DNA polymerase η motif II alter bypass of DNA lesions (2001) (59)
The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity (2003) (58)
Mutability of DNA polymerase I: implications for the creation of mutant DNA polymerases. (2005) (58)
Mutagenesis in vitro by DNA polymerase from an RNA tumour virus (1979) (58)
Distinctive properties of mammalian DNA polymerases. (1979) (57)
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan. (2019) (57)
Sea urchin nuclear DNA polymerase. I. Localization in nuclei during rapid DNA synthesis. (1969) (57)
Role of depurination in mutagenesis by chemical carcinogens. (1982) (57)
The Enzymatic Activities of the Werner Syndrome Protein Are Disabled by the Amino Acid Polymorphism R834C* (2004) (57)
Mutants generated by the insertion of random oligonucleotides into the active site of the beta-lactamase gene. (1989) (57)
Mutagenic DNA polymerase in human leukemic cells. (1973) (56)
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. (1981) (55)
Microsatellite instability induced by hydrogen peroxide in Escherichia coli. (2000) (55)
Rearrangements of DNA mediated by terminal transferase. (1986) (55)
Microsome-specific stimulation by phenobarbital of amino acid incorporation in vivo. (1965) (54)
On the origin of multiple mutations in human cancers. (1998) (54)
Comparison of the relative mutagenicities of O-alkylthymines site-specifically incorporated into phi X174 DNA. (1987) (53)
Oxygen radical induced mutagenesis is DNA polymerase specific. (1994) (53)
Generation of mutator mutants during carcinogenesis. (2006) (53)
Mutagenesis in vitro by depurination of ΦX174 DNA (1981) (52)
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation. (1975) (51)
Multi-stage proofreading in DNA replication (1993) (51)
On the fidelity of DNA replication. Metal activation of Escherichia coli DNA polymerase I. (1979) (51)
Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase. (2010) (51)
Insertion of the T3 DNA polymerase thioredoxin binding domain enhances the processivity and fidelity of Taq DNA polymerase. (2003) (50)
Werner syndrome protein interacts functionally with translesion DNA polymerases (2007) (50)
The Conserved Active Site Motif A of Escherichia coliDNA Polymerase I Is Highly Mutable* (2001) (50)
Mutagenesis resulting from depurination is an SOS process. (1982) (50)
Permissible amino acid substitutions within the putative nucleoside binding site of herpes simplex virus type 1 encoded thymidine kinase established by random sequence mutagenesis [corrected]. (1992) (50)
Depurination decreases fidelity of DNA synthesis in vitro (1977) (50)
DNA damage and repair in brain: relationship to aging. (1992) (48)
Mutagenicity and pausing of HIV reverse transcriptase during HIV plus- strand DNA synthesis (1994) (48)
Hydrolysis of 3'-terminal mispairs in vitro by the 3' ⇒ 5' exonuclease of DNA polymerase δ permits subsequent extension by DNA polymerase α (1990) (48)
Incorporation of reporter-labeled nucleotides by DNA polymerases. (2005) (48)
The mutator phenotype in cancer: molecular mechanisms and targeting strategies. (2010) (45)
Creating novel enzymes by applied molecular evolution. (1997) (45)
Negative Clonal Selection in Tumor Evolution (2005) (45)
Metal binding to DNA polymerase I, its large fragment, and two 3',5'-exonuclease mutants of the large fragment. (1990) (45)
The mutagenic effect of deoxynucleotide substrate imbalances during DNA synthesis with mammalian DNA polymerases. (1982) (45)
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. (2004) (44)
The Werner Syndrome Protein Is Distinguished from the Bloom Syndrome Protein by Its Capacity to Tightly Bind Diverse DNA Structures (2012) (44)
Distribution of Mutations in Human Thymidylate Synthase Yielding Resistance to 5-Fluorodeoxyuridine* (2002) (44)
Highly Tolerated Amino Acid Substitutions Increase the Fidelity of Escherichia coli DNA Polymerase I* (2007) (43)
Reverse transcriptase: correlation of zinc content with activity. (1974) (43)
Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria. (1996) (43)
On the fidelity of DNA replication. Studies with human placenta DNA polymerases. (1979) (43)
Transient Expression of a Mutator Phenotype in Cancer Cells (1997) (43)
Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli. (1993) (43)
Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis. (1998) (43)
Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers. (2013) (42)
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I. (1975) (42)
RNA-dependent DNA polymerase: presence in normal human cells. (1971) (42)
Metal-induced lethality and mutagenesis: possible role of apurinic intermediates. (1987) (42)
On the fidelity of DNA replication. The accuracy of Escherichia coli DNA polymerase I in copying natural DNA in vitro. (1980) (41)
Oxidative DNA Damage and Mutagenesis (1998) (41)
Why Cockayne syndrome patients do not get cancer despite their DNA repair deficiency (2016) (40)
RNA-dependent DNA polymerase in human lymphocytes during gene activation by phytohaemagglutinin. (1971) (40)
DNA polymerase. Correlation with DNA replication during transformation of human lymphocytes. (1971) (40)
Metal-induced infidelity of DNA synthesis. (1981) (40)
Random Sequence Mutagenesis and Resistance to 5-Fluorouridine in Human Thymidylate Synthases* (1998) (39)
Mutation spectrum of copper-induced DNA damage. (1992) (39)
A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion. (1992) (39)
In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion. (1996) (38)
Werner Syndrome, aging and cancer. (2006) (38)
On the fidelity of DNA replication. Accuracy of Escherichia coli DNA polymerase I. (1979) (38)
Resistance of HeLa cell mitochondrial DNA to mutagenesis by chemical carcinogens. (1988) (38)
The Werner Syndrome Exonuclease Facilitates DNA Degradation and High Fidelity DNA Polymerization by Human DNA Polymerase δ* (2012) (38)
In vivo mutagenesis by Escherichia coli DNA polymerase I. Ile(709) in motif A functions in base selection. (2001) (37)
Manganese as a mutagenic agent during in vitro DNA synthesis. (1975) (37)
Animal cell DNA polymerases in DNA repair. (1990) (37)
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro. (1984) (36)
Extensive subclonal mutational diversity in human colorectal cancer and its significance (2019) (36)
Mutations in the R2 Subunit of Ribonucleotide Reductase That Confer Resistance to Hydroxyurea* (2004) (35)
Tumbling down a different pathway to genetic instability. (2003) (35)
Mutator phenotype in cancer: origin and consequences. (2010) (35)
Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis. (1998) (35)
Zinc in reverse transcriptase. (1974) (35)
S1 nuclease does not cleave DNA at single-base mis-matches. (1981) (35)
Nucleotide sequence preservation of human leukemic mitochondrial DNA. (1985) (35)
On the fidelity of DNA replication. Characterization of polynucleotides with errors in base-pairing synthesized by avian myeloblastosis virus deoxyribonucleic acid polymerase. (1975) (34)
Screening for deficits in DNA repair by the response of irradiated human lymphocytes to phytohemagglutinin. (1977) (33)
DNA sequences of random origin as probes of Escherichia coli promoter architecture. (1988) (33)
Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts. (1990) (33)
Ageing: Mice and mitochondria (2004) (33)
A Mitochondrial view of aging, reactive oxygen species and metastatic cancer (2010) (33)
Erroneous base-pairing induced by a chemical carcinogen during DNA synthesis (1974) (32)
Infidelity of DNA synthesis as related to mutagenesis and carcinogenesis. (1977) (32)
Many mutations in cancers. (1996) (32)
METHYLCHOLANTHRENE-INDUCED CHANGES IN RAT LIVER NUCLEAR RNA. (1964) (32)
Thymidine kinase mutants obtained by random sequence selection. (1993) (32)
Genomic stability and instability: a working paradigm. (1997) (32)
When Pol I Goes into High Gear: Processive DNA Synthesis by Pol I in the Cell (2004) (31)
On the activity and fidelity of chromatin‐associated hepatic DNA polymerase‐β in aging murine species of different life spans (1981) (31)
Dna replication in human lymphocytes during aging (1978) (31)
Creation of human alkyltransferases resistant to O6-benzylguanine. (1997) (31)
Cancer: One cell at a time (2014) (31)
Sea urchin nuclear DNA polymerase. IV. Reversible association of DNA polymerase with nuclei during the cell cycle. (1972) (30)
Increased Sensitivity of Microsomes from Phenobarbital-Treated Rats to Synthetic Messenger RNA (Polyuridylic Acid): Lack of Effect on Ribosomes (1965) (30)
Structure of Drosophila melanogaster dAT replicated in an in vitro system. (1970) (30)
Critical role of R-loops in processing replication blocks. (2005) (30)
Proofreading by the epsilon subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase alpha. (1989) (30)
Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli. (1995) (29)
Fidelity of DNA polymerases isolated from regenerating liver chromatin of aging Mus musculus. (1985) (29)
Detection of Ultra-Rare Mitochondrial Mutations in Breast Stem Cells by Duplex Sequencing (2015) (28)
Apurinic sites as common intermediates in mutagenesis. (1986) (28)
Origin of multiple mutations in human cancers. (1998) (28)
Intracellular migration of DNA polymerase in early developing sea urchin embryos. (1970) (28)
Potential sources of multiple mutations in human cancers. (1995) (27)
Human Ku Antigen Tightly Binds and Stabilizes a Tetrahelical Form of the Fragile X Syndrome d(CGG) n Expanded Sequence* (2000) (27)
Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication (2011) (25)
Site-specific mutagenesis by error-directed DNA synthesis (1982) (25)
Lymphocyte function in normal people with persistent Australia antigen. (1973) (25)
Molecular aspects of somatic hypermutation of immunoglobulin genes. (1999) (25)
On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization. (1981) (24)
On mitochondria, mutations, and methodology. (2009) (24)
On the fidelity of DNA replication. Isolation of high fidelity DNA polymerase-primase complexes by immunoaffinity chromatography. (1987) (24)
Taq DNA Polymerase (2002) (24)
Avian myeloblastosis virus DNA polymerase. Kinetic studies on the incorporation of noncomplementary nucleotides. (1975) (24)
A Rapid Assay for Measuring Nucleotide Excision Repair by Oligonucleotide Retrieval (2014) (24)
Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations (2017) (23)
Studies on the induction of DNA polymerase during transformation of human lymphocytes. (1972) (23)
The role of metal ions in the mechanisms of DNA and RNA polymerases. (1979) (23)
DNA polymerase-α: enzymology, function, fidelity, and mutagenesis (1986) (23)
Specificity of proofreading by the 3'----5' exonuclease of the DNA polymerase-primase of Drosophila melanogaster. (1988) (22)
On the fidelity of DNA synthesis. Pyrophosphate-induced misincorporation allows detection of two proofreading mechanisms. (1986) (22)
Clonal Expansions and Short Telomeres Are Associated with Neoplasia in Early-onset, but not Late-onset, Ulcerative Colitis (2013) (22)
Active Site Mutations in Mammalian DNA Polymerase δ Alter Accuracy and Replication Fork Progression* (2010) (22)
Herpes thymidine kinase mutants with altered catalytic efficiencies obtained by random sequence selection. (1994) (21)
Mitochondrial DNA integrity is not dependent on DNA polymerase-β activity (2006) (21)
Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells (2001) (21)
Infidelity of DNA synthesis by reverse transcriptase. (1973) (21)
Endogenous mutagenesis and cancer. (2002) (21)
On the fidelity of DNA replication: herpes DNA polymerase and its associated exonuclease. (1987) (20)
The three faces of the WS helicase (1998) (20)
Redesigning the substrate specificity of human O(6)-alkylguanine-DNA alkyltransferase. Mutants with enhanced repair of O(4)-methylthymine. (1999) (20)
DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication (1995) (20)
Effects of altered nucleotide concentrations on the fidelity of DNA replication. (1985) (19)
Lymphocyte Transformation and Hepatitis I. Impairment of Thymidine Incorporation and DNA Polymerase Activity 1 (1971) (19)
Detection of tandem CC-->TT mutations induced by oxygen radicals using mutation-specific PCR. (1999) (19)
Fidelity of DNA Polymerase‐β in Neurons from Young and Very Aged Mice (1985) (19)
Single-Molecule Sequencing Reveals Patterns of Preexisting Drug Resistance That Suggest Treatment Strategies in Philadelphia-Positive Leukemias (2018) (19)
Infidelity of DNA synthesis: a general property of RNA tumor viruses. (1974) (19)
Creation of RNA molecules that recognize the oxidative lesion 7,8-dihydro-8-hydroxy-2'-deoxyguanosine (8-oxodG) in DNA. (1998) (19)
Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase. (2001) (19)
Transfer RNA methylases during sea urchin embryogenesis. (1971) (18)
Tolerance of different proteins for amino acid diversity (1996) (18)
Selection of new biological activities from random nucleotide sequences: evolutionary and practical considerations. (1989) (18)
Structure-function relationships in Escherichia coli promoter DNA. (1990) (18)
Human O(6)-alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes. (1999) (18)
Artificial mutants generated by the insertion of random oligonucleotides into the putative nucleoside binding site of the HSV-1 thymidine kinase gene. (1991) (18)
On the association of reverse transcriptase with polynucleotide templates during catalysis. (1976) (18)
Inefficient repair of RNA x DNA hybrids. (1997) (18)
Stimulation of Ammo-acid Incorporation by Nuclear Ribonucleic Acid from Normal and Methylcholanthrene-treated Rats (1963) (17)
The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the malaria parasite Plasmodium falciparum. (2011) (17)
Apparent suicidal inactivation of DNA polymerase by adenosine 2',3'-riboepoxide 5'-triphosphate. (1978) (17)
Metal content of DNA polymerase I purified from overproducing and wild type Escherichia coli. (1983) (17)
Sequence specificity of pausing by DNA polymerases. (1989) (16)
Evolutionary dynamics and significance of multiple subclonal mutations in cancer. (2017) (16)
Metal-induced infidelity of DNA synthesis. (1981) (16)
Functional interaction between the Werner Syndrome protein and DNA polymerase d (2000) (16)
Amino Acid Substitutions at Conserved Tyrosine 52 Alter Fidelity and Bypass Efficiency of Human DNA Polymerase η* (2003) (16)
Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase alpha. (1993) (16)
A random mutation capture assay to detect genomic point mutations in mouse tissue (2011) (16)
A Mutator Phenotype in Cancer 1 (2001) (16)
UV irradiation alters deoxynucleoside triphosphate pools in Escherichia coli. (1984) (16)
On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses. (1976) (16)
Selection of new biologically active molecules from random nucleotide sequences. (1993) (15)
Methylation of transfer RNA during transformation of human lymphocytes by phytohemagglutinin. (1973) (15)
DNA polymerase alpha and models for proofreading (1985) (15)
Priming of DNA polymerase in nuclei of sea urchin embryos by native DNA. (1967) (15)
Mitochondrial mutagenesis induced by tumor-specific radiation bystander effects (2010) (15)
On the fidelity of DNA replication. Lack of primer position effect on the fidelity of mammalian DNA polymerases. (1984) (14)
Effect of DNA-repair enzymes on mutagenesis by oxygen free radicals. (1993) (14)
Restriction of carcinogen-induced error incorporation during in vitro DNA synthesis. (1976) (14)
A Substitution in the Fingers Domain of DNA Polymerase δ Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site* (2013) (14)
Exploring the implications of distinct mutational signatures and mutation rates in aging and cancer (2016) (14)
Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells. (2016) (13)
Mutations in DNA polymerase η are not detected in squamous cell carcinoma of the skin (2006) (13)
Tolerance of 5-fluorodeoxyuridine resistant human thymidylate synthases to alterations in active site residues. (1999) (13)
Infidelity of DNA synthesis as related to mutagenesis and carcinogenesis. (1977) (13)
In vitro production and screening of DNA polymerase eta mutants for catalytic diversity. (2002) (12)
Molecular association of DNA polymase with chromatin in sea urchin embryos. (1970) (12)
Transfection of the DNA polymerase-alpha gene. (1984) (12)
Enzymatic properties of rat DNA polymerase beta mutants obtained by randomized mutagenesis. (2001) (12)
FUNCTIONAL MUTANTS OBTAINED BY RANDOM MUTAGENESIS COUPLED WITH GENETIC SELECTION IN ESCHERICHIA COLI (1996) (12)
Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. (2006) (12)
Effect of hyperthermia on the survival of normal human peripheral blood mononuclear cells. (1983) (12)
LOH-proficient embryonic stem cells: a model of cancer progenitor cells? (2007) (12)
Purification and characterization of cytosolic phospholipase A2 activities from canine myocardium and sheep platelets. (1991) (12)
On the fidelity of DNA replication. Specificity of nucleotide substitution by intercalating agents. (1983) (12)
Mechanisms of neoplastic transformation. (1983) (12)
Mutations in the α8 Loop of Human APE1 Alter Binding and Cleavage of DNA Containing an Abasic Site* (2003) (12)
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase (1995) (11)
Endogenous mutations and cancer. (1991) (11)
Use of Pol I-deficient E. coli for functional complementation of DNA polymerase. (2003) (11)
A comparison of several methods of assay of carbon-14 in protein. (1965) (11)
Factor D is a selective single-stranded oligodeoxythymidine binding protein (1988) (11)
Hydrolysis of 3'-terminal mispairs in vitro by the 3'----5' exonuclease of DNA polymerase delta permits subsequent extension by DNA polymerase alpha. (1990) (10)
Enhanced in vivo repair of O(4)-methylthymine by a mutant human DNA alkyltransferase. (2000) (10)
On the fidelity of DNA replication. Mechanisms of misincorporation by intercalating agents. (1983) (10)
Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells (2006) (9)
Genetic complementation protocols. (2003) (9)
Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype (2017) (9)
On the fidelity of DNA synthesis:effects of steroids and intercalating agents. (1980) (9)
The association of thymidine kinase activity and thymidine transport in Escherichia coli. (1991) (9)
Werner syndrome gene variants in human sarcomas (2010) (9)
Template recognition and chain elongation in DNA synthesis in vitro. (1976) (9)
Sphingosine, a Modulator of Human Translesion DNA Polymerase Activity* (2014) (9)
On the fidelity of DNA replication: use of synthetic oligonucleotide-initiated reactions. (1985) (8)
Proofreading by the £ subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase a ( nudeotide misinsertion / lack of mispair extension / 3 '-5 ' exonuclease / mispair hydrolysis / proofreading mechanism ) (8)
On the fidelity of deoxyribonucleic acid synthesis directed by chromatin-associated deoxyribonucleic acid polymerase beta. (1980) (8)
When Pol I goes into high gear (2004) (8)
DNA Polymerase α-Primase Complexes from Carcinogen-treated Chinese Hamster Ovary Cells (1990) (8)
Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival. (2008) (8)
Reply: Is There Any Genetic Instability in Human Cancer? (2010) (8)
In vitro DNA synthesis in the presence of antibody to homogeneous E. coli DNA polymerase. (1971) (8)
Rare Mutations in Cancer Drug Resistance and Implications for Therapy (2020) (8)
Direct selection of mutations in the human mitochondrial tRNAThr gene: reversion of an 'uncloneable' phenotype. (1988) (8)
MULTIPLE DNA POLYMERASES. DISPLAYED BY ISOELECTRIC FOCUSING * (1973) (8)
Infidelity of DNA synthesis by themperature-sensitive DNA polymerases from RNA tumor viruses. (1977) (7)
Infidelity of DNA synthesis (1977) (7)
Multipotent mutator strain of mouse teratocarcinoma cells (1985) (7)
Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells. (2009) (7)
A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells (2019) (7)
Lymphocyte Transformation and Hepatitis II. Lack of Direct in Vitro Inhibition by Purified Australia Antigen 1 (1971) (7)
Initiation of DNA synthesis in eucaryotes: a model in vitro system. (1970) (7)
Ribonucleic acid dependent deoxyribonucleic acid synthesis by Escherichia coli deoxyribonucleic acid polymerase. I. Characterization of the polymerization reaction. (1974) (7)
Inhibitors of mammalian DNA polymerases: Possible chemotherapeutic approaches (1977) (7)
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. (2003) (7)
Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate. (1997) (7)
Unnatural nucleotide sequences in biopharmaceutics. (1996) (7)
Random sequence mutagenesis for the generation of active enzymes. (1996) (6)
Infidelity of DNA replication as a basis of mutagenesis. (1983) (6)
Erratum: Human cancers express a mutator phenotype (Proceedings of the National Academy of Sciences of the United States of America (November 28, 2006) 103, 48 (18238-18242) DOI: 10.1073/pnas.0607057103) (2006) (6)
Site specific mutagenesis: insertion of single noncomplementary nucleotides at specified sites by error-directed DNA polymerization. (1984) (6)
AUSTRALIA ANTIGEN (A HEPATITIS-ASSOCIATED ANTIGEN) (1970) (6)
Chapter 15 - KINETIC AND MAGNETIC RESONANCE STUDIES OF THE INTERACTION OF Mn 2+ , SUBSTRATES AND TEMPLATES WITH DNA POLYMERASES (1986) (6)
DNA Polymerase I and Klenow Fragment (2002) (5)
DNA Polymerase Activity in Human Serum: Studies with Australia Antigen (1973) (5)
Isolation and characterization of DNA polymerases from eukaryotic cells. (1978) (5)
Depurination of DNA as a possible mutagenic pathway for cells. (1982) (5)
Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase et (5)
Applied Molecular Evolution of Enzymes Involved in Synthesis and Repair of DNA (2003) (5)
Base substitution mutagenesis by terminal transferase: its role in somatic mutagenesis. (1987) (5)
Tobacco Causes Human Cancers--A Concept Founded on Epidemiology and an Insightful Experiment Now Requires Translation Worldwide. (2016) (4)
O-Alkyl deoxythymidines are recognized by DNA polymerase I as deoxythymidine or deoxycytidine. (1987) (4)
Heat mutagenesis of bacteriophage ΦX174 in SOS-induced bacteria (1982) (4)
A High-Resolution Landscape of Mutations in the BCL6 Super-Enhancer in Normal Human B-Cells (2019) (4)
Random oligonucleotide mutagenesis. (2003) (4)
Enzymatic synthesis of site-specifically modified DNA. (1988) (4)
Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2. (1991) (4)
The DNA sequence specificity of stimulation of DNA polymerases by factor D. (1987) (4)
Induction of DNA Polymerase in Mixed Lymphocyte Cultures (1970) (4)
Workshop report from the Division of Research Grants, National Institutes of Health. Site-specific mutagenesis--a Chemical Pathology Study Section Workshop. (1989) (4)
DNA polymerase-alpha: enzymology, function, fidelity, and mutagenesis. (1986) (4)
Mouse teratocarcinoma cells resistant to aphidicolin and arabinofuranosyl cytosine: Isolation and initial characterization (1983) (4)
Assessment of the carcinogenic potential of a proposed food coloring additive, laccaic acid, using short-term assays (1984) (4)
Analysis of the Sub-Clonal Origins of Compound Mutations in Patients with Refractory Ph+ Malignancies Treated with Ponatinib (2016) (3)
FIDELITY OF COPYING NATURAL DNA TEMPLATES (1980) (3)
FIDELITY OF DNA SYNTHESIS DURING AGING (1984) (3)
High Throughput Drug Screening of Leukemia Stem Cells Reveals Resistance to Standard Therapies and Sensitivity to Other Agents in Acute Myeloid Leukemia (2018) (3)
Princess takamatsu symposium on DNA repair and human cancers. (2010) (3)
DNA replication of X-irradiated human lymphocytes. (1981) (3)
The multiplicity of mutations in human cancers. (2005) (3)
Mutations based on viral decay acceleration in the HIV-1 genomes of a clinical population treated with the mutagenic nucleoside KP1461 (2011) (3)
In Vivo Mutagenesis by Escherichia coliDNA Polymerase I (2001) (3)
Lack of microsatellite instability in human prostate-cancer. (1995) (3)
Infidelity of DNA synthesis as a cause of mutagenesis. (1983) (2)
High fidelity taq polymerases for mutation detection (1997) (2)
ON THE FIDELITY OF DNA REPLICATION1 (1978) (2)
On Mutagenic DNA Polymerases and Malignancy (1975) (2)
Fidelity of DNA polymerase-beta in neurons from young and very aged mice. (1985) (2)
Mutational spectra of aflatoxin B (2017) (2)
DNA polymerase 6 is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae [ CDC 2 ( POL 3 ) / DNA polymerase a / DNA polymerase E / DNA replicadon / functional complementationJ (1)
Research Report In Vitro Production and Screening of DNA Polymerase η Mutants for Catalytic Diversity (2002) (1)
DNA polymerase alpha-primase complexes from carcinogen-treated Chinese hamster ovary cells. (1990) (1)
Ultra-sensitive sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan (2018) (1)
Alteration in the fidelity of DNA synthesis by beryllium (1976) (1)
22 DNA Helicases and Human Disease (2006) (1)
Co-Occurring Mutation Clusters Predict Drug Sensitivity in Acute Myeloid Leukemia (2020) (1)
Evidence against DNA polymerase beta as a candidate gene for Werner syndrome. (1994) (1)
Screening for Deficits in DNA Repair Using Human Lymphocytes (1980) (1)
DNA Repair Enzymes (2006) (1)
748 Duplex sequencing reveals the effects of caffeine on reducing UV-induced mutations of cancer-relevant genes (2019) (1)
Aphidicolin-resistant mutator strains of mouse teratocarcinoma (1987) (1)
One small StEP in molecular evolution… (1998) (1)
DNA Helicases and Human Disease (2005) (1)
Mutagenesis in Humans (2002) (1)
Evidence against DNA polymerase β as a candidate gene for Werner syndrome (1994) (1)
Emergence of Sub-Clonal Drug Resistance Mutations during CML Therapy (2015) (1)
Unexpectedly High Subclonal Mutational Diversity in Human Colorectal Cancer and Its Significance (2019) (1)
Lymphocyte function in mothers of patients with Down's syndrome. (1971) (1)
The first US-Japan meeting on error-prone DNA synthesis, Maui, Hawaii, December 20-21, 2004. (2005) (1)
Mutagenic potential of 04-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis (1999) (1)
Targeted mutagenesis in E. coli: A powerful tool for the generation of random mutant libraries. (2003) (1)
Abstract 3041: Duplex Sequencing detects cancer-associated mutations arising during normal aging: Clonal evolution over a century of human lifetime (2017) (1)
Deoxynucleoside [ 1-thioltriphosphates prevent proofreading during in vitro DNA synthesis ( phosphorothioate nucleotides / fidelity of DNA synthesis / DNA polymerases ) (0)
DNA‐Dependent DNA Polymerases (2002) (0)
Chemical Carcinogens Resistance of HeLa Cell Mitochondrial DNA to Mutagenesis by Updated (2006) (0)
Introduction: Avoidance of Spontaneously Occurring Errors in DNA (1986) (0)
Purification and Properties of Deoxyribonucleic Acid Polymerase from Nuclei of Sea Urchin Embryos 4 (2003) (0)
Oxidants and multiple mutations in cancer (1996) (0)
Abstract 2071: Sub-clonal heterogeneity and risk of treatment failure in Philadelphia-positive leukemias (2017) (0)
Creation ofdrug-specific herpes simplex virustype1thymidine kinasemutantsforgenetherapy (1996) (0)
PolyG-DS: An ultrasensitive polyguanine tract–profiling method to detect clonal expansions and trace cell lineage (2021) (0)
Abstract 1776: Loss of estrogen receptor alters drug responsiveness and supports a basal-like phenotype in endocrine-resistant HER2+/ER+ breast cancer (2022) (0)
Mutagenesis based on depurination by chemical carcinogens (1982) (0)
Abstract 5493: Lethal mutagenesis of cancer cells by nucleoside analogs (2011) (0)
Abstract 1789A: Duplex DNA sequencing detects subclonal and ultra-rare mutations in human tumors. (2013) (0)
Innovative funding for cancer research: California's antismoking initiative (1990) (0)
XPG and WRN: An unexpected partnership (2011) (0)
Abstract 4890: Duplex sequencing of AML reveals extensive sub clonal heterogeneity (2015) (0)
Abstract LB-338: Extensive subclonal mutations in human colorectal cancers detected by duplex sequencing (2016) (0)
Abstract 241: A mutant DNA polymerase-delta associated with increased tumor progression causes random deletions in DNA (2010) (0)
A mutator phenotype in human cancers: Origin and consequences. (2006) (0)
My personal thoughts on the recent joint U.S./Japan cancer meeting in Honolulu, Hawaii. (1989) (0)
Abstract LB-283: Human cancers harbor extensive subclonal mutations (2015) (0)
Error Catastrophe and Compounds Against RNA Viruses (2003) (0)
O III A.1 Creation of new mutant DNA repair enzymes (1997) (0)
Infidelity of DNA replication in malignant cells. (1972) (0)
Depurination causes mutations in SOS-induced cells ( chemical carcinogenesis / mutagenesis / fidelity of DNA replication / SOS repair ) (0)
Deregulated DNA Polymerase (cid:1) Induces Chromosome Instability and Tumorigenesis 1 (2002) (0)
Creation of rna molecules that recognize the oxidative biomarker 8-oxodg in DNA (1998) (0)
Heat mutagenesis of bacteriophage phi X174 in SOS-induced bacteria. (1982) (0)
Corrigendum: Detecting ultralow-frequency mutations by Duplex Sequencing (2014) (0)
Heat mutagenesis of bacteriophage phi X174 in SOS-induced bacteria. (1982) (0)
Molecular Errata (1997) (0)
Abstract 2395: Direct assessment of sequence heterogeneity in human cancers by Duplex Sequencing (2016) (0)
Smoking and Lung Cancer : An Overview 1 ' 2 (2006) (0)
Exploring the implications of distinct mutational signatures and mutation rates in aging and cancer (2016) (0)
Limits to the Human Cancer Genome Project? (2007) (0)
Genomic and Chromosomal Instability (2006) (0)
SHORT REPORT Mutations in DNA polymerase g are not detected in squamous cell carcinoma of the skin (2006) (0)
Do mutator mutations fuel tumorigenesis? (2013) (0)
Nucleotide sequence preservation of human mitochondrial DNA ( mutation / evolution / recombinant DNA / DNA sequencing (2003) (0)
Correspondence re: Lawrence A. Loeb et al. Smoking and Lung Cancer: An Overview. Cancer Res., 44: 5940–5958, 1984 — Reply 1 (1986) (0)
Construction of human tumor viruses? (1976) (0)
Forced evolution of O6-methlyguanine DNA methyltransferase to create a more efficient DNA repair protein (1996) (0)
Selection of novel eukaryotic DNA polymerases by mutagenesis and genetic complementation of yeast. (2003) (0)
Abstract 2846: Ultrasensitive detection of actionable subclones in chronic myeloid leukemia (2015) (0)
Procedes et compositions de criblage de medicaments anti-sida (1995) (0)
ENVIRONMENTAL MUTAGEN SOCIETY Thirty-Fourth Annual Meeting Environmental Mutagenesis: From Mechanisms to Risk Assessment (2003) (0)
Abstract 3770: Unexpectedly high subclonal mutational diversity in human colorectal cancer and its significance (2019) (0)
Site-specific mutagenesis by polymerase-catalyzed incorporation of alkyl-deoxyribonucleoside triphosphate (dNTP) adducts into ΦX174 DNA (1985) (0)
Polymerases thermostables presentant une fidelite modifiee (1997) (0)
Abstract A29: Detection of ultra-rare mutations during breast stem cell tumor progression by Duplex Sequencing (2016) (0)
Reactive Oxygen Species in Tumorigenesis 1 (2006) (0)
DNA Polymerase Activity Sphingosine , a Modulator of Human DNA and Chromosomes : (2014) (0)
Accurate detection of subclonal variants in paired diagnosis-relapse acute myeloid leukemia samples by next generation Duplex Sequencing. (2022) (0)
Macrophage Stimulating 1 Receptor (2011) (0)
FUTURE ANNUAL MEETINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (2017) (0)
Abstract AP05: ULTRA–DEEP SEQUENCING DETECTS OVARIAN CANCER CELLS IN PERITONEAL FLUID AND REVEALS SOMATIC TP53 MUTATIONS IN NON–CANCEROUS TISSUES (2017) (0)
P III C.6 A positive selection assay for genomic instability (1997) (0)
Probing the mechanism of radical abstraction of the small subunit of E. coli ribonucleotide reductase (2003) (0)
Correlation of genomic analysis by MyAML with chemotherapy drug sensitivity. (2015) (0)
Resistance of the DNA strand in RNA-DNA hybrids to DNA repair (1997) (0)
Controversies in the Basic Sciences: Is There an Inducible Error-Prone Pathway in Mammalian Cells That Is Responsible for Mutations by Many Chemical Carcinogens? (1985) (0)
Acknowledgement to Reviewers (2004) (0)
Mutation at the Polymerase Active Site of Mouse DNA Polymerase (cid:2) Increases Genomic Instability and Accelerates Tumorigenesis (cid:1) (2007) (0)
Targeted Ultra-Deep High Accuracy Sequencing of Pre-Treatment AML Reveals a Diversity of Mutational Phenotypes and Evidence of Preexisting Relapse-Associated Subclones (2014) (0)
Tumor Promoters: An Editorial Comment (1983) (0)
DNA repair and human cancers : Extended abstracts for the 40th International Symposium of the Princess Takamatsu Cancer Research Fund : November 10-12, 2009 Tokyo, Japan (2010) (0)
Molecular Analysis of Lymphocyte Transformation (2018) (0)
Abstract 445: Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues (2016) (0)
Richmond T. Prehn: In Memoriam (1922-2016). (2017) (0)

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