Lawrence A. Tabak

Lawrence A. Tabak's AcademicInfluence.com Rankings

Lawrence A. Tabak

Medical

#445

World Rank

#611

Historical Rank

#182

USA Rank

Dentistry

#13

World Rank

#25

Historical Rank

USA Rank

medical Degrees

Lawrence A. Tabak

Biology

#2076

World Rank

#3343

Historical Rank

#952

USA Rank

Biochemistry

#356

World Rank

#427

Historical Rank

#140

USA Rank

biology Degrees

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Why Is Lawrence A. Tabak Influential?

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According to Wikipedia, Lawrence A. Tabak is an American dentist and biomedical scientist serving as the principal deputy director of the National Institutes of Health. He served as acting director from 2021 to 2023. Previously he was the director of the National Institute of Dental and Craniofacial Research from 2000 to 2010.

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Lawrence A. Tabak's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Policy: NIH plans to enhance reproducibility (2014) (1038)
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. (2012) (640)
Role of salivary mucins in the protection of the oral cavity. (1982) (489)
All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases. (2003) (451)
In defense of the oral cavity: structure, biosynthesis, and function of salivary mucins. (1995) (368)
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination. (1995) (266)
Structural Aspects of Salivary Glycoproteins (1987) (238)
NIH plans to enhance reproducibility (2014) (221)
Specificity of salivary-bacterial interactions: II. Evidence for a lectin on Streptococcussanguis with specificity for a NeuAcα2,3Ga1β1,3Ga1NAc sequence (1982) (168)
A revolution in biomedical assessment: the development of salivary diagnostics. (2001) (160)
Dynamic Association between the Catalytic and Lectin Domains of Human UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase-2* (2006) (148)
The beginnings of mucin biosynthesis: the crystal structure of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-T1. (2004) (137)
Masticatory lubrication. The role of carbohydrate in the lubricating property of a salivary glycoprotein-albumin complex. (1985) (134)
Reduced chemotactic peptide binding in juvenile periodontitis: a model for neutrophil function. (1981) (133)
Handbook of Glycosyltransferases and Related Genes (2014) (132)
Emerging Paradigms for the Initiation of Mucin-type Protein O-Glycosylation by the Polypeptide GalNAc Transferase Family of Glycosyltransferases* (2011) (130)
Initiation of Protein O Glycosylation by the Polypeptide GalNAcT-1 in Vascular Biology and Humoral Immunity (2007) (121)
Cloning and Expression of a Novel, Tissue Specifically Expressed Member of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Family* (1998) (116)
Purification of a low-molecular-weight, mucin-type glycoprotein from human submandibular-sublingual saliva. (1982) (115)
Structure and function of human salivary mucins. (1990) (112)
Association of Free Arginine and Lysine Concentrations in Human Parotid Saliva with Caries Experience (1995) (111)
Characterization of a UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase That Displays Glycopeptide N-Acetylgalactosaminyltransferase Activity* (1999) (103)
Cloning and Characterization of a Ninth Member of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Family, ppGaNTase-T9* (2001) (102)
Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold. (1999) (101)
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. (2011) (101)
The effect of milk and casein proteins on the adherence of Streptococcus mutans to saliva-coated hydroxyapatite. (1994) (99)
Purification, cloning, and expression of a bovine UDP-GalNAc: polypeptide N-acetyl-galactosaminyltransferase. (1993) (98)
Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. (2004) (93)
cDNA Cloning and Expression of a Novel UDP-N-acetyl-d-galactosamine:PolypeptideN-Acetylgalactosaminyltransferase* (1997) (92)
Adsorption of human salivary mucins to hydroxyapatite. (1985) (90)
Artificial Salivas: Present and Future (1987) (89)
The influence of flanking sequence on the O-glycosylation of threonine in vitro. (1992) (88)
Preliminary characterization of material eluted from the roots of periodontally diseased teeth. (1980) (86)
Age-related Changes in Mucins from Human Whole Saliva (1991) (86)
Weaving a Richer Tapestry in Biomedical Science (2011) (84)
In defense of the oral cavity: the protective role of the salivary secretions. (2006) (75)
The Catalytic and Lectin Domains of UDP-GalNAc:Polypeptide α-N-Acetylgalactosaminyltransferase Function in Concert to Direct Glycosylation Site Selection* (2008) (72)
Properties of Cysteine-containing Phosphoproteins from Human Submandibular-sublingual Saliva (1982) (71)
Adherence of Streptococcus sanguis to salivary mucin bound to glass. (1982) (71)
The role of mucin-type O-glycans in eukaryotic development. (2010) (70)
Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family. (2003) (69)
Immunochemical quantitation of alpha-amylase and secretory IgA in parotid saliva from people of various ages. (1987) (69)
Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. (2000) (69)
Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family. (2016) (67)
UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. (2012) (66)
The Lectin Domain of the Polypeptide GalNAc Transferase Family of Glycosyltransferases (ppGalNAc Ts) Acts as a Switch Directing Glycopeptide Substrate Glycosylation in an N- or C-terminal Direction, Further Controlling Mucin Type O-Glycosylation* (2013) (66)
Characterization of Low-molecular-weight Peptides in Human Parotid Saliva (1995) (65)
Juvenile Periodontitis as a Model for Neutrophil Function: Reduced Binding of the Complement Chemotactic Fragment, C5a (1983) (65)
Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library. (2004) (64)
Influence of milk, lactose-reduced milk, and lactose on caries in desalivated rats. (1991) (64)
Saliva: a significant factor in removable prosthodontic treatment. (1987) (63)
Preparation of a sialic acid-binding protein from Streptococcus mitis KS32AR (1986) (63)
The Association of Basic Proline-rich Peptides from Human Parotid Gland Secretions with Caries Experience (2000) (60)
The influence of flanking sequences on O-glycosylation. (1991) (60)
Guidelines for Saliva Nomenclature and Collection (1993) (58)
Glycopeptide-preferring Polypeptide GalNAc Transferase 10 (ppGalNAc T10), Involved in Mucin-type O-Glycosylation, Has a Unique GalNAc-O-Ser/Thr-binding Site in Its Catalytic Domain Not Found in ppGalNAc T1 or T2* (2009) (56)
Cloning and expression of mouse UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3. (1996) (56)
Cariology for the Nineties (1993) (55)
Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation (2021) (53)
Point‐of‐Care Diagnostics Enter the Mouth (2007) (52)
Charge Distribution of Flanking Amino Acids Influences O-Glycan Acquisition in Vivo(*) (1996) (51)
Molecular characterization of glutamic acid/glutamine-rich secretory proteins from rat submandibular glands. (1987) (49)
Light and electron microscopic immunolocalization of rat submandibular gland mucin glycoprotein and glutamine/glutamic acid-rich proteins. (1989) (49)
Affirming NIH’s commitment to addressing structural racism in the biomedical research enterprise (2021) (49)
Lipid Composition of Submandibular Saliva from Normal and Cystic Fibrosis Individuals (1982) (47)
Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation (2021) (43)
Structure of the carbohydrate chains of the proline-rich glycoprotein from human parotid saliva. (1982) (42)
The Isolation of a Family of Cysteine-containing Phosphoproteins from Human Submandibular-Sublingual Saliva (1982) (41)
Initial characterization of the carbohydrate structure of MCP-1. (1991) (39)
The National Institute of Dental and Craniofacial Research: research for the practicing dentist. (2005) (39)
Molecular cloning of a rat submandibular gland apomucin. (1994) (39)
Changes in lactoferrin and other proteins in a case of chronic recurrent parotitis. (1978) (38)
Examination of rat salivary glands for the presence of the aquaporin CHIP (1994) (38)
Characterization of Cysteine-containing Phosphoproteins from Human Submandibular-Sublingual Saliva (1982) (37)
Isoform-specific O-Glycosylation of Osteopontin and Bone Sialoprotein by Polypeptide N-Acetylgalactosaminyltransferase-1* (2009) (36)
A computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2. (2014) (35)
Galnt1 Is Required for Normal Heart Valve Development and Cardiac Function (2015) (35)
Purification and characterization of monkey salivary mucin. (1979) (35)
Isolation and characterization of a mucin-glycoprotein from rat submandibular glands. (1985) (34)
Kinetic Analysis of a Recombinant UDP-N-acetyl-D-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase (*) (1995) (33)
A molecular switch orchestrates enzyme specificity and secretory granule morphology (2018) (31)
Genetics and its implications for clinical dental practice and education: report of panel 3 of the Macy study. (2008) (31)
Artificial Salivas: Present and Future (1987) (31)
Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding (2019) (30)
Substrate-induced conformational changes and dynamics of UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase-2. (2007) (30)
Charge distribution of flanking amino acids inhibits O-glycosylation of several single-site acceptors in vivo. (1997) (30)
A Framework for Decisions About Research with HPAI H5N1 Viruses (2013) (29)
Isoform-specific O-glycosylation by murine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3, in vivo. (1998) (28)
Specificity of O-glycosylation by bovine colostrum UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferase using synthetic glycopeptide substrates (1996) (27)
Limulus Lysate Activity of Lipoteichoic Acids (1977) (27)
Studies in plaque pathogenicity. I. Plaque collection and limulus lysate screening of adherent and loosely adherent plaque. (1978) (26)
Specificity of salivary-bacterial interactions: II. Evidence for a lectin on Streptococcus sanguis with specificity for a NeuAc alpha 2, 3Ga1 beta 1, 3Ga1NAc sequence. (1982) (26)
Basic science: Bedrock of progress. (2016) (25)
A Comparison of Serine and Threonine O-Glycosylation by UDP-GaINAc:Polypeptide N-Acetylgalactosaminyltransferase (1993) (25)
Identification of essential histidine residues in UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T1. (1997) (25)
Analysis of isoproterenol-induced changes in parotid gland gene expression. (2002) (25)
Studies in plaque pathogenicity. II. A technique for the specific detection of endotoxin in plaque samples using the limulus lysate assay. (1978) (24)
Role of saliva (pellicle), diet, and nutrition on plaque formation (1989) (22)
A call for increased education in genetics for dental health professionals. (2004) (22)
Opinion: The Next Generation Researchers Initiative at NIH (2017) (22)
Circular dichroism and fluorescence spectroscopic analyses of a proline-rich glycoprotein from human parotid saliva. (2009) (20)
A new assessment in vitro of human salivary lubrication using a compliant substrate. (1990) (20)
ARPA-H: Accelerating biomedical breakthroughs (2021) (20)
The effect of chronic propranolol treatment on salivary composition and caries in the rat. (1990) (19)
An Inhibitor of O-Glycosylation Induces Apoptosis in NIH3T3 Cells and Developing Mouse Embryonic Mandibular Tissues* (2004) (19)
Functional expression of the rat anion exchanger AE2 in insect cells by a recombinant baculovirus. (1993) (18)
A view of the future: dentistry and oral health in America. (2009) (18)
Establishment and characterization of 12S adenoviral E1A immortalized rat submandibular gland epithelial cells. (1990) (17)
Expression of glutamine/glutamic acid-rich proteins in rat submandibular glands. (1990) (16)
Global Oral Health Inequalities (2011) (16)
The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function (2019) (15)
Secretagogue-coupled changes in the expression of glutamine/glutamic acid-rich proteins (GRPs). Isoproterenol induces changes in GRP transcript expression and changes in isoforms secreted. (1991) (15)
NIH Roadmap Interdisciplinary Research Initiatives (2005) (14)
Neuraminidase Activity: A Biochemical Marker to Distinguish Streptococcus mitis from Streptococcus sanguis (1984) (14)
Rapid evolution of variants in a rodent multigene family encoding salivary proteins. (1989) (14)
Oral health research at the crossroads: translate we must! (2004) (14)
cDNA Cloning and Expression of a Novel UDP- N -acetyl- D -galactosamine:Polypeptide N -Acetylgalactosaminyltransferase* (1997) (14)
Biomedical research: strength from diversity. (2013) (13)
The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1 (2004) (13)
Facilitated DNA transfer to rat submandibular gland in vivo and GRP-Ca gene regulation. (1995) (13)
The GalNAc-T Activation Pathway (GALA) is not a general mechanism for regulating mucin-type O-glycosylation (2017) (12)
Characterization of sulphated monosaccharides from stumptail monkey (Macaca arctoides) salivary mucin. (1981) (12)
The Effect of Chronic Atropine Treatment on Salivary Composition and Caries in Rats (1989) (12)
Cloning and sequence homology of a rat UDP-GalNAc:polypeptideN-acetylgalactosaminyltransferase (1995) (11)
Members of the GalNAc-T family of enzymes utilize distinct Golgi localization mechanisms (2018) (11)
The US National Institutes of Health approach to inclusive excellence (2021) (11)
Separation of glycopeptides from in vitro O-glycosylation reactions using C18 cartridges. (1993) (10)
Cloning and sequence homology of a rat UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase. (1995) (9)
Beyond the "omics": translating science into improved health. (2008) (9)
Isolation and characterization of tracheobronchial mucin from a laryngectomee. (1984) (9)
UDP-N-acetyl-α-D-galactosamine: Polypeptide N-acetylgalactosaminyltransferases: Completion of the family tree(Glycobiology (2012) 22: 6 (768-777) DOI:10.1093/glycob/cwr183) (2015) (8)
Dentistry on the road(map). (2004) (8)
Characterization of a pentasaccharide in salivary mucin from the stumptail monkey, Macaca arctoides. (1982) (8)
The Partnership for Accelerating Cancer Therapies (2018) (8)
Dental, Oral, and Craniofacial Research: the View from the NIDCR (2004) (7)
Biosynthesis of a low-molecular-mass rat submandibular gland mucin glycoprotein in COS7 cells. (1997) (7)
Characterization of the gene encoding the salivary Gln/Glu-rich C-terminal variant A protein. (1991) (7)
Isolation and partial characterization of a genus common antigen and species specific antigen of Capnocytophaga. (1982) (7)
Structure-Function Analysis of the UDP-N-acetyl-d-galactosamine:PolypeptideN-acetylgalactosaminyltransferase (1999) (6)
Columbia, Salivary Research, plus Irwin Mandel Equal a Special Combination for Dentistry (1997) (6)
National Institutes of Health efforts on sexual and gender minority health research. (2014) (6)
An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues. (2008) (5)
Expression of a functional rat salivary cystatin S polypeptide in Escherichia coli. (1995) (5)
Chromosomal organization and expression analysis of two distinct genes encoding glutamine/glutamic acid-rich proteins. (1997) (5)
Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos (2017) (5)
Genetic regulation of salivary proteins in rodents. (1991) (5)
Precision Health: Bringing Oral Health into the Context of Overall Health (2019) (4)
Improved online LC-MS/MS identification of O-glycosites by EThcD fragmentation, chemoenzymatic reaction, and SPE enrichment (2020) (4)
Polypeptide N-Acetylgalactosaminyltransferases (2002) (4)
Genetic Control of Salivary Mucin Formation1 (1991) (4)
Affinity chromatography of antiserum to a gram negative organism. (1977) (3)
Improvement of oral health in the postgenomic era: opportunities for government/industry partnerships. (2001) (3)
Conducting and putting science into practice: the future of oral health research, dental education, and dental practice. (2002) (3)
Structures of the O-glycosidic Units of a Mucin-gycoprotein from Rat Submandibular Glands (1982) (3)
Reproducibility in Biomedical Research (2019) (3)
Race Disparity in Grants: Oversight at Home—Response (2011) (2)
Research Opportunities to Address Nutrition Insecurity and Disparities. (2022) (2)
Differential splicing of the lectin domain of an O-glycosyltransferase modulates both peptide and glycopeptide preferences (2020) (2)
Foreign Influences on Research Integrity (2018) (2)
A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis (2022) (2)
Response to: "Rescuing the NIH before it is too late". (2006) (2)
Immunochemistry of Monkey Salivary Mucin (1982) (2)
Molecular cloning and characterization of the gene encoding rat submandibular gland apomucin,Mucsmg (1996) (1)
O‐glycosylation of the novel SARS‐CoV‐2 coronavirus spike protein influences furin cleavage (2021) (1)
Response (2019) (1)
Moving Beyond the Cheshire Cat: Research in Oral Health Behavior (2008) (1)
Erratum: UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. (2015) (1)
Aab Institute of Biomedical Sciences (1999) (1)
Clinical Science (1982) (1)
Facing the Future: the NIDCR Celebrates its 60th Anniversary (2008) (1)
All in the family: the role of the UDP N‐acetylgalactosamine polypeptide: alpha‐N‐acetylgalactosaminyltransferases (ppGalNAc T’s) in development and disease in the craniofacial complex (2006) (0)
Preface (1998) (0)
Growth Factors do not regulate Golgi Complex-to-ER relocation of GalNAc-Ts in HeLa cells (2016) (0)
Molecular biology of protein secretion in exocrine cells (1994) (0)
New directions in dentistry--the role of the National Institute of Dental and Craniofacial Research. (2003) (0)
Memoriam on the Life of Dr. William Bowen (2017) (0)
Acetylgalactosaminyltransferase-1 N Polypeptide Osteopontin and Bone Sialoprotein by-Glycosylation of O Isoform-specific Glycobiology and Extracellular Matrices : (2009) (0)
Summary (1993) (0)
Mouth to mouth (2004) (0)
In Memoriam: Irwin D. Mandel, the Ninth President of the AADR (2011) (0)
Looking forward. (2022) (0)
Salivary gland biogenesis and function (1998) (0)
The Role of Periodontics for Hospital and Geriatric Medicine (2009) (0)
The Crisis in Clinical Research: Panel Discussion III (2010) (0)
Proline and Threonine Analogues Fail to Alter the Glycosylatin of Rat Submandibular Gland Mucin (1983) (0)
Maximizing Investigators' Research Awards: An experiment to promote a more productive, efficient and sustainable biomedical research enterprise (2014) (0)
Chemotactic Fragment, C5a Juvenile Periodontitis as a Model for Neutrophil Function: Reduced Binding of the Complement (2011) (0)
Crystal Structure of the Drosophila Melanogaster Polypeptide N-Acetylgalactosaminyl Transferase PGANT9B (2018) (0)
Crystal Structure of the Drosophila Melanogaster Polypeptide N-Acetylgalactosaminyl Transferase PGANT9A in Complex with UDP and Mn2+ (2018) (0)
Guest Editorial: A Modest Proposal to Help Ameliorate a Problem in the American Dental Profession (1990) (0)
Salivary Mucin Secretion (2011) (0)
sanguis Neuraminidase Activity: A Biochemical Marker to Distinguish Streptococcus mitis from Streptococcus (2011) (0)
Characterization of the Salivary Glutamine/Glutamic Acid Rich Protein Gene Encoding the Isoproterenol Repressible GRP Variant Ca (GRP-Ca) Transcript. L.F. COOPER* and L.A. TABAK (Department of Dental Research, University of Rochester, Rochester, NY, USA) (1991) (0)
Human oral microbiology is at a crossroads. (2010) (0)
PRACTICE-BASED RESEARCH: Author's response (2005) (0)
In Real Life (2014) (0)
Oral care products (1995) (0)
Saliva Characterization of Cysteine-containing Phosphoproteins from Human Submandibular-Sublingual (2011) (0)
In a World of Global Positioning System, Why a Roadmap? and Is Translational Research a 2-Way Street? (2010) (0)
Series : Molecular Medicine Institutions Aab Institute of Biomedical Sciences (2007) (0)
A molecular switch orchestrates enzyme specificity and secretory granule morphology (2018) (0)

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University of Rochester

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Published Works

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Lawrence A. Tabak's AcademicInfluence.com Rankings